Page last updated: 2024-08-25

honokiol and Breast Neoplasms

honokiol has been researched along with Breast Neoplasms in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (16.67)29.6817
2010's16 (53.33)24.3611
2020's9 (30.00)2.80

Authors

AuthorsStudies
Cai, D; Guan, S; Li, D; Liu, D; Wang, J; Xing, G; Yue, L; Zhang, Q1
Lu, X; Lv, H; Yang, P; Zhang, Z1
Cai, D; Guan, S; Li, D; Li, H; Li, X; Liu, D; Wang, J; Xing, G; Yue, L; Zhang, Q; Zhu, W1
Abbasi, SW; Akbar, A; Jahangir, M; Mehnaz, S; Raza, RZ; Riasat, A; Shahid, I; Shoaib, M1
Hardisty, S; Kerr, K; McAlister, K; McCullough, I; Thulasiraman, P; Wistner, A1
He, K; Jiang, M; Li, J; Liu, Q; Qiu, T; Sun, J; Yang, M; Zhan, S; Zhang, X1
Hafiz, AA; Haggag, YA; Ibrahim, RR1
Cai, D; Fan, L; Guan, S; Liu, D; Wang, J; Zhang, Q; Zhu, W1
Lou, L; Wang, J; Xiong, J; Yi, X; Zhou, S1
Chen, Y; Hu, X; Li, J; Li, Y; Qu, J; Wang, D; Wang, Z; Xia, M; Yuan, R; Zhang, H; Zhang, Y1
Afthinos, A; Arbiser, JL; Begum, A; Bonner, MY; Cho, S; Győrffy, B; Huang, CY; Konstantopoulos, K; Korangath, P; Kuppusamy, P; Lanoue, D; Marignani, PA; Matsui, W; Merino, VF; Mistriotis, P; Muniraj, N; Nagalingam, A; Saxena, NK; Sengupta, S; Sharma, D; Shriver, M; Sukumar, S1
Deng, Y; He, C; Jin, Y; Li, X; Liu, Y; Qu, X; Wang, D; Wang, Z; Zhou, Y; Zou, Y1
Cheng, L; Ju, RJ; Li, CQ; Li, XT; Liu, S; Peng, XM; Qiu, X; Song, XL; Wang, T1
Guo, Y; Han, M; Liu, B; Wang, X; Yu, R; Zou, Y1
Chen, SZ; Li, Y; Shang, Y; Wang, WD1
Arbiser, JL; Avtanski, DB; Bonner, MY; Nagalingam, A; Saxena, NK; Sharma, D2
Arbiser, JL; Avtanski, DB; Bonner, MY; Kuppusamy, P; Nagalingam, A; Saxena, NK; Sharma, D1
Alitongbieke, G; Cai, L; Chen, QC; Jiang, F; Liu, J; Meng, M; Ren, A; Shi, X; Su, Y; Wang, G; Wang, J; Xie, L; Xu, Y; Zeng, Z; Zhang, X; Zhang, XK; Zhou, H; Zhou, Y1
Johnson, AB; Thulasiraman, P1
Gong, C; He, T; Nie, S; Song, L; Wang, N; Wang, Z; Wu, Q; Yang, S; Yang, X; Yi, C1
Chen, L; Chen, X; Hou, W; Hu, J; Jiang, Q; Tang, M; Wang, X; Wei, Y; Wen, J; Yang, G; Yuan, Y; Zhong, Z; Zhou, H1
Elstner, E; Emde, A; Eucker, J; Kühnl, A; Liu, H; Planas-Silva, MD; Possinger, K; Rosche, M; Schulz, CO; Zang, C1
Bae, K; Chung, HJ; Hong, JY; Hung, TM; Kang, SS; Kang, YJ; Kim, YS; Lee, SK; Min, HY; Park, EJ; Youn, UJ1
Katiyar, SK; Singh, T1
Arbiser, JL; Bonner, MY; Nagalingam, A; Saxena, NK; Sharma, D1
Deng, Y; He, H; Li, L; Sun, J; Tian, W; Xu, D1
Chen, Q; Hou, X; Wang, S; Yuan, X; Zhang, B1
Hu, X; Lu, Q; Xu, D1
Amblard, F; Arbiser, JL; Karlan, BY; Koeffler, HP; Nguyen, A; O'Kelly, J; Wakimoto, N; Wolf, I1

Other Studies

30 other study(ies) available for honokiol and Breast Neoplasms

ArticleYear
Tumor-targeted delivery of honokiol via polysialic acid modified zein nanoparticles prevents breast cancer progression and metastasis.
    International journal of biological macromolecules, 2022, Apr-01, Volume: 203

    Topics: Animals; Biphenyl Compounds; Breast Neoplasms; Drug Carriers; Female; Humans; Lignans; Mice; Nanoparticles; Particle Size; Sialic Acids; Tissue Distribution; Zein

2022
Honokiol nanosuspensions loaded thermosensitive hydrogels as the local delivery system in combination with systemic paclitaxel for synergistic therapy of breast cancer.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2022, Aug-01, Volume: 175

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Hydrogels; Lignans; Mice; Nanoparticles; Paclitaxel

2022
Polysialic acid-functionalized liposomes for efficient honokiol delivery to inhibit breast cancer growth and metastasis.
    Drug delivery, 2023, Volume: 30, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Humans; Liposomes; Mice

2023
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:12

    Topics: Biphenyl Compounds; Breast Neoplasms; Female; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Serine-Threonine Kinases

2023
Neuraminidase 1 regulates proliferation, apoptosis and the expression of Cadherins in mammary carcinoma cells.
    Molecular and cellular biochemistry, 2019, Volume: 462, Issue:1-2

    Topics: Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Proliferation; Female; Humans; Lignans; N-Acetylneuraminic Acid; Neuraminidase

2019
Tuning mPEG-PLA/vitamin E-TPGS-based mixed micelles for combined celecoxib/honokiol therapy for breast cancer.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2020, Apr-15, Volume: 146

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Celecoxib; Lignans; Mice; Mice, Inbred BALB C; Polyesters; Polyethylene Glycols; Vitamin E

2020
Design, Formulation and in vivo Evaluation of Novel Honokiol-Loaded PEGylated PLGA Nanocapsules for Treatment of Breast Cancer.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Drug Delivery Systems; Female; Humans; Lignans; MCF-7 Cells; Mice; Micelles; Nanocapsules; Polyethylene Glycols; Polyglactin 910; Solubility; Xenograft Model Antitumor Assays

2020
Targeted delivery of honokiol by zein/hyaluronic acid core-shell nanoparticles to suppress breast cancer growth and metastasis.
    Carbohydrate polymers, 2020, Jul-15, Volume: 240

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cell Movement; Cell Proliferation; Drug Carriers; Drug Screening Assays, Antitumor; Female; Hyaluronic Acid; Lignans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nanoparticles; Tumor Cells, Cultured; Zein

2020
Honokiol antagonizes doxorubicin resistance in human breast cancer via miR-188-5p/FBXW7/c-Myc pathway.
    Cancer chemotherapy and pharmacology, 2021, Volume: 87, Issue:5

    Topics: Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; F-Box-WD Repeat-Containing Protein 7; Female; Gene Expression Regulation, Neoplastic; Humans; Lignans; MicroRNAs; Proto-Oncogene Proteins c-myc; Signal Transduction

2021
Augment the efficacy of eradicating metastatic lesions and tumor proliferation in breast cancer by honokiol-loaded pH-sensitive targeted lipid nanoparticles.
    Colloids and surfaces. B, Biointerfaces, 2021, Volume: 207

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Hydrogen-Ion Concentration; Lignans; Lipids; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nanoparticles

2021
Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.
    Oncogene, 2017, 10-12, Volume: 36, Issue:41

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Female; Humans; Lignans; Mice; Neoplastic Stem Cells; Protein Serine-Threonine Kinases; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2017
Concurrently suppressing multidrug resistance and metastasis of breast cancer by co-delivery of paclitaxel and honokiol with pH-sensitive polymeric micelles.
    Acta biomaterialia, 2017, 10-15, Volume: 62

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Breast Neoplasms; Drug Delivery Systems; Female; Humans; Lignans; MCF-7 Cells; Neoplasm Metastasis; Paclitaxel

2017
Hyaluronic acid modified daunorubicin plus honokiol cationic liposomes for the treatment of breast cancer along with the elimination vasculogenic mimicry channels.
    Journal of drug targeting, 2018, Volume: 26, Issue:9

    Topics: Animals; Biphenyl Compounds; Breast Neoplasms; Cations; Daunorubicin; Female; Humans; Hyaluronic Acid; Lignans; Liposomes; MCF-7 Cells; Mice; Neovascularization, Pathologic

2018
Surface modification of pH-sensitive honokiol nanoparticles based on dopamine coating for targeted therapy of breast cancer.
    Colloids and surfaces. B, Biointerfaces, 2019, May-01, Volume: 177

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Breast Neoplasms; Cell Proliferation; Drug Carriers; Drug Screening Assays, Antitumor; Female; Folic Acid; Hydrogen-Ion Concentration; Indoles; Lignans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nanoparticles; Optical Imaging; Particle Size; Polymers; Surface Properties

2019
Honokiol inhibits breast cancer cell metastasis by blocking EMT through modulation of Snail/Slug protein translation.
    Acta pharmacologica Sinica, 2019, Volume: 40, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Humans; Lignans; Lung Neoplasms; Mice, Inbred BALB C; Snail Family Transcription Factors

2019
Honokiol inhibits epithelial-mesenchymal transition in breast cancer cells by targeting signal transducer and activator of transcription 3/Zeb1/E-cadherin axis.
    Molecular oncology, 2014, Volume: 8, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast; Breast Neoplasms; Cadherins; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Homeodomain Proteins; Humans; Lignans; Magnolia; Signal Transduction; STAT3 Transcription Factor; Transcription Factors; Zinc Finger E-box-Binding Homeobox 1

2014
Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA-34a dependent manner.
    Oncotarget, 2015, Jun-30, Volume: 6, Issue:18

    Topics: Animals; Antineoplastic Agents, Phytogenic; beta Catenin; Biphenyl Compounds; Breast Neoplasms; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Drugs, Chinese Herbal; Female; Histone Deacetylases; Humans; Leptin; Lignans; Magnolia; MCF-7 Cells; Mice; Mice, Nude; Mice, Obese; MicroRNAs; Neoplasm Invasiveness; Obesity; Phosphorylation; Plant Extracts; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Spheroids, Cellular; STAT3 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Wnt1 Protein; Xenograft Model Antitumor Assays

2015
Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer.
    Oncotarget, 2015, Oct-06, Volume: 6, Issue:30

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Blotting, Western; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Leptin; Lignans; MCF-7 Cells; Mice; MicroRNAs; Microscopy, Confocal; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Xenograft Model Antitumor Assays

2015
Honokiol sensitizes breast cancer cells to TNF-α induction of apoptosis by inhibiting Nur77 expression.
    British journal of pharmacology, 2016, Volume: 173, Issue:2

    Topics: Animals; Apoptosis; Biphenyl Compounds; Breast Neoplasms; Drugs, Chinese Herbal; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Hep G2 Cells; Humans; Lignans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nuclear Receptor Subfamily 4, Group A, Member 1; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays

2016
Regulation of Mucin 1 and multidrug resistance protein 1 by honokiol enhances the efficacy of doxorubicin-mediated growth suppression in mammary carcinoma cells.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Breast Neoplasms; Down-Regulation; Doxorubicin; Drug Synergism; Female; Gene Expression; Humans; Lignans; MCF-7 Cells; Mucin-1; Multidrug Resistance-Associated Proteins; RNA, Small Interfering; Transfection

2016
Biodegradable polymeric micelles coencapsulating paclitaxel and honokiol: a strategy for breast cancer therapy in vitro and in vivo.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biocompatible Materials; Biphenyl Compounds; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Liberation; Endocytosis; Female; HEK293 Cells; Humans; Immunohistochemistry; Lignans; Mice, Inbred BALB C; Micelles; Paclitaxel; Particle Size; Polymers

2017
Synergistic antitumor effects of liposomal honokiol combined with adriamycin in breast cancer models.
    Phytotherapy research : PTR, 2008, Volume: 22, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Drugs, Chinese Herbal; Female; Lignans; Liposomes; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Xenograft Model Antitumor Assays

2008
Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer.
    European journal of pharmacology, 2008, Sep-04, Volume: 591, Issue:1-3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Lapatinib; Lignans; Magnolia; Medicine, Chinese Traditional; Quinazolines; Signal Transduction; Sirolimus; Time Factors

2008
Down-regulation of c-Src/EGFR-mediated signaling activation is involved in the honokiol-induced cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells.
    Cancer letters, 2009, May-18, Volume: 277, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; CSK Tyrosine-Protein Kinase; Down-Regulation; ErbB Receptors; Female; Humans; Lignans; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Tumor Suppressor Proteins

2009
Honokiol, a phytochemical from Magnolia spp., inhibits breast cancer cell migration by targeting nitric oxide and cyclooxygenase-2.
    International journal of oncology, 2011, Volume: 38, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Movement; Cyclooxygenase 2; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Female; Humans; Lignans; Magnolia; Mice; Models, Biological; Molecular Targeted Therapy; Nitric Oxide; Phytotherapy

2011
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.
    Breast cancer research : BCR, 2012, Feb-21, Volume: 14, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Biphenyl Compounds; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Enzyme Activation; Female; Gene Expression; Humans; Lignans; Mice; Mice, Nude; Neoplasm Invasiveness; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Spheroids, Cellular; TOR Serine-Threonine Kinases; Tumor Burden; Xenograft Model Antitumor Assays

2012
Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death.
    International journal of oncology, 2013, Volume: 42, Issue:2

    Topics: Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cyclophilins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Lignans; MCF-7 Cells; Peptidyl-Prolyl Isomerase F

2013
Screening active anti-breast cancer compounds from Cortex Magnolia officinalis by 2D LC-MS.
    Journal of separation science, 2013, Volume: 36, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; Humans; Lignans; Magnolia; Mass Spectrometry

2013
Down-regulation of P-glycoprotein expression in MDR breast cancer cell MCF-7/ADR by honokiol.
    Cancer letters, 2006, Nov-18, Volume: 243, Issue:2

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Drugs, Chinese Herbal; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Lignans; Magnolia; Rhodamine 123; RNA, Messenger; Time Factors

2006
Honokiol, a natural biphenyl, inhibits in vitro and in vivo growth of breast cancer through induction of apoptosis and cell cycle arrest.
    International journal of oncology, 2007, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biphenyl Compounds; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Doxorubicin; Drug Synergism; Female; Humans; Hydroxamic Acids; In Vitro Techniques; Lignans; Mice; Mice, Nude; Paclitaxel; Tamoxifen; Vorinostat

2007