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homovanillic acid and Spasms, Infantile

homovanillic acid has been researched along with Spasms, Infantile in 7 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)

Research Excerpts

ExcerptRelevanceReference
"The 18 patients had either West syndrome (12 patients) or Lennox-Gastaut syndrome (6 patients), which was intractable to antiepileptic drug therapy and to adrenocorticotrophic hormone."1.29Thyrotropin-releasing hormone in treatment of intractable epilepsy: neurochemical analysis of CSF monoamine metabolites. ( Kawase, S; Matsuo, S; Mitsufuji, N; Nishimura, A; Sawada, T; Takeuchi, Y; Tominaga, M; Yamazoe, I, 1995)
"1) Only one of 27 children with West syndrome and related disorders pretreated using high-dose PAL-P alone before ACTH showed a clinically excellent response."1.28Combination treatment of high-dose pyridoxal phosphate and low-dose ACTH in children with West syndrome and related disorders. ( Seki, T, 1990)
"Homovanillic acid levels were significantly increased in these patients, while 3-methoxy-4-hydroxyphenylethylene glycol and 5-hydroxyindoleacetic acid were not significantly altered, as compared with controls."1.26Elevated homovanillic acid in cerebrospinal fluid of children with infantile spasms. ( Ito, M; Mikawa, H; Okuno, T; Osumi, Y, 1980)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ito, M1
Okuno, T1
Mikawa, H1
Osumi, Y1
Silverstein, F1
Johnston, MV1
Takeuchi, Y1
Tominaga, M1
Mitsufuji, N1
Yamazoe, I1
Kawase, S1
Nishimura, A1
Matsuo, S1
Sawada, T1
Airaksinen, E1
Tuomisto, L1
Riikonen, R1
Seki, T2
Kimiya, S1
Maezawa, M1
Yamada, T1
Tachibana, Y1
Sugie, H1
Sugie, Y1
Kato, N1
Fukuyama, Y1

Other Studies

7 other studies available for homovanillic acid and Spasms, Infantile

ArticleYear
Elevated homovanillic acid in cerebrospinal fluid of children with infantile spasms.
    Epilepsia, 1980, Volume: 21, Issue:4

    Topics: Adrenocorticotropic Hormone; Age Factors; Child, Preschool; Dopamine; Homovanillic Acid; Humans; Hyd

1980
Cerebrospinal fluid monoamine metabolites in patients with infantile spasms.
    Neurology, 1984, Volume: 34, Issue:1

    Topics: Adolescent; Child; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylacetates

1984
Thyrotropin-releasing hormone in treatment of intractable epilepsy: neurochemical analysis of CSF monoamine metabolites.
    Pediatric neurology, 1995, Volume: 12, Issue:2

    Topics: Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Homovanillic Acid; Humans; Hydrox

1995
The concentrations of GABA, 5-HIAA and HVA in the cerebrospinal fluid of children with infantile spasms and the effects of ACTH treatment.
    Brain & development, 1992, Volume: 14, Issue:6

    Topics: Adolescent; Adrenocorticotropic Hormone; Analysis of Variance; Child; Child, Preschool; gamma-Aminob

1992
Combination treatment of high-dose pyridoxal phosphate and low-dose ACTH in children with West syndrome and related disorders.
    The Japanese journal of psychiatry and neurology, 1990, Volume: 44, Issue:2

    Topics: Child, Preschool; Cosyntropin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug

1990
Analysis of monamine metabolism in cerebrospinal fluid in childhood epilepsies.
    The Japanese journal of psychiatry and neurology, 1989, Volume: 43, Issue:3

    Topics: Adolescent; Brain Damage, Chronic; Child; Child, Preschool; Epilepsies, Myoclonic; Epilepsy; Epileps

1989
A patient with infantile spasms and low homovanillic acid levels in cerebrospinal fluid: L-dopa dependent seizures?
    European journal of pediatrics, 1989, Volume: 148, Issue:7

    Topics: Dopamine; Female; Homovanillic Acid; Humans; Infant; Levodopa; Pyridoxine; Spasms, Infantile

1989