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homovanillic acid and Schizophrenia

homovanillic acid has been researched along with Schizophrenia in 410 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
" We investigated the effects of aripiprazole and blonanserin on clinical symptoms and plasma levels of homovanillic acid (pHVA) and 3-methoxy-4hydroxyphenylglycol in the switching strategy of schizophrenia."9.19Switching antipsychotics to aripiprazole or blonanserin and plasma monoamine metabolites levels in patients with schizophrenia. ( Kanno-Nozaki, K; Katsumi, A; Mashiko, H; Miura, I; Niwa, S; Shiga, T; Yabe, H, 2014)
" We examined the effects of the Taq1A polymorphism on the plasma monoamine metabolites during the treatment of schizophrenia with aripiprazole, a DRD2 partial agonist."9.16Effects of aripiprazole and the Taq1A polymorphism in the dopamine D2 receptor gene on the clinical response and plasma monoamine metabolites level during the acute phase of schizophrenia. ( Kanno, K; Katsumi, A; Mashiko, H; Miura, I; Mori, A; Niwa, S; Numata, Y; Takeuchi, S; Yang, Q, 2012)
"We investigated the effects of aripiprazole on plasma levels of brain-derived neurotrophic factor (BDNF) and catecholamine metabolites in first-episode untreated schizophrenia patients."9.16Aripiprazole altered plasma levels of brain-derived neurotrophic factor and catecholamine metabolites in first-episode untreated Japanese schizophrenia patients. ( Atake, K; Hayashi, K; Hori, H; Ikenouchi-Sugita, A; Katsuki, A; Nakamura, J; Tomita, M; Umene-Nakano, W; Yoshimura, R, 2012)
"In the treatment of acute schizophrenia, risperidone and aripiprazole are both placed the first line antipsychotics."9.16Effect of switching to risperidone after unsuccessful treatment with aripiprazole on plasma monoamine metabolites level in the treatment of acute schizophrenia. ( Kanno, K; Katsumi, A; Mashiko, H; Miura, I; Niwa, S; Takeuchi, S; Watanabe, K, 2012)
"This study tested the hypothesis that plasma homovanillic acid (pHVA) levels, a peripheral measure of central dopaminergic activity, would predict the change in memory performance in patients with schizophrenia treated with clozapine."9.11Prediction of changes in memory performance by plasma homovanillic acid levels in clozapine-treated patients with schizophrenia. ( Jayathilake, K; Kim, CH; Lee, MA; Meltzer, HY; Roy, A; Sumiyoshi, C; Sumiyoshi, T, 2004)
"An open-label study was performed to investigate the clinical efficacy and mechanisms of risperidone liquid in ameliorating positive symptoms in the acute phase of schizophrenia."9.11An open study of risperidone liquid in the acute phase of schizophrenia. ( Egami, H; Goto, M; Kaji, K; Kakihara, S; Kohara, K; Maeda, H; Nakamura, J; Ninomiya, H; Shinkai, K; Ueda, N; Yamada, Y; Yoshimura, R, 2005)
"We have previously reported that risperidone might improve negative symptoms in schizophrenia by influencing noradrenergic neurons."9.10Plasma levels of homovanillic acid and the response to risperidone in first episode untreated acute schizophrenia. ( Nakamura, J; Shinkai, K; Ueda, N; Yoshimura, R, 2003)
"We have investigated plasma homovanillic acid (pHVA) and 3-methoxy-4-hydroxyphenylglycol (pMHPG) concentrations in 34 DSM-III-R neuroleptic-treated schizophrenic patients who were classified into deficit (n = 14) and nondeficit (n = 20) forms of schizophrenia."9.08Plasma 3-methoxy-4-hydroxyphenylglycol and homovanillic acid measurements in deficit and nondeficit forms of schizophrenia. ( Dollfus, S; Dourmap, N; Ménard, JF; Petit, M; Ribeyre, JM; Thibaut, F, 1998)
"The introduction of the atypical neuroleptic, clozapine, has had widespread influence not only on the treatment of the seriously mentally ill patient, but also on new drug development and on hypotheses of the pathophysiology of schizophrenia."9.07Predictors of clozapine response in schizophrenia. ( Hsiao, JK; Litman, RE; Owen, RR; Pickar, D; Su, TP, 1994)
"Twenty-one patients with schizophrenia who met criteria for neuroleptic treatment resistance or intolerance participated in a crossover, placebo-controlled, double-blind comparison of long-term typical neuroleptic and clozapine treatment."9.07Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine. ( Gutierrez, R; Konicki, E; Litman, RE; Owen, RR; Pickar, D; Rapaport, MH, 1992)
"Plasma homovanillic acid (HVA) levels were measured hourly for a 24-hour period in 10 patients with schizophrenia during treatment with placebo and fluphenazine."9.06Circadian variation of plasma homovanillic acid levels is attenuated by fluphenazine in patients with schizophrenia. ( Doran, AR; Douillet, P; Labarca, R; Pickar, D; Roy, A; Wolkowitz, OM, 1990)
"Previous studies have variably reported the efficacy of apomorphine in treatment of schizophrenia and tardive dyskinesia."9.05Apomorphine and schizophrenia. Treatment, CSF, and neuroendocrine responses. ( Davis, BM; Davis, KL; Horvath, TB; Kendler, KS; Levy, MI; Mathé, AA; Mohs, RC; Trigos, G, 1984)
"Aripiprazole has been reported to exert variable effects on cognitive function in patients with schizophrenia."7.85Blood Biomarkers Predict the Cognitive Effects of Aripiprazole in Patients with Acute Schizophrenia. ( Atake, K; Beppu, H; Hori, H; Igata, R; Katsuki, A; Konishi, Y; Tominaga, H; Yoshimura, R, 2017)
"To study the role of dopamine neurotransmission in schizophrenia and its drug treatment by assessing the relationship of plasma homovanillic acid (pHVA), a major central dopamine metabolite to various clinical parameters in schizophrenic patients."7.71Relationship of symptomatology, gender, and antipsychotic drug treatment with plasma homovanillic acid in schizophrenia. ( Peet, M; Ramchand, C; Reynolds, GP; Shah, S; Zhang, ZJ, 2001)
"To examine plasma homovanillic acid (pHVA) levels in first-episode schizophrenia, to compare pHVA levels in patients and controls, and to assess the association of pHVA levels with psychopathology and treatment response."7.69Plasma homovanillic acid levels in first-episode schizophrenia. Psychopathology and treatment response. ( Alvir, J; Amin, F; Chakos, M; Cooper, T; Koreen, AR; Lieberman, J; Loebel, A; Mayerhoff, D, 1994)
"Increased noradrenergic activity during chronic dopamine blockade may be an episode marker and may predict relapse within 6 weeks following haloperidol withdrawal in schizophrenia."7.69Noradrenergic activity and prediction of psychotic relapse following haloperidol withdrawal in schizophrenia. ( Agren, H; Gurklis, J; O'Connor, DT; Peters, JL; van Kammen, DP; Yao, JK, 1994)
"In the week prior to discontinuation of haloperidol treatment, global behavioral ratings and a lumbar puncture for cerebrospinal fluid monoamine metabolities were obtained in 88 patients with chronic schizophrenia."7.69Behavioral vs biochemical prediction of clinical stability following haloperidol withdrawal in schizophrenia. ( Gilbertson, MW; Gurklis, JA; Kelley, ME; Peters, JL; van Kammen, DP; Yao, JK, 1995)
"Plasma homovanillic acid concentration was assessed in 60 young schizophrenic patients, with and without first-degree relatives with schizophrenia, before treatment, and 3 days after starting haloperidol treatment."7.69Schizophrenia: gender, family risk, and plasma homovanillic acid. ( Andía, I; Basterreche, E; Dávila, R; Friedhoff, AJ; González-Torres, MA; Guimón, J; Zamalloa, MI; Zumárraga, M, 1995)
"In a series of studies tyrosine transport was investigated in patients with schizophrenia."7.69Tyrosine transport as an indicator of cell membrane dysfunction in schizophrenia. ( Bjerkenstedt, L; Wiesel, FA, 1996)
"The dopamine hypotheses of schizophrenia and antipsychotic drug action suggest that the dopamine metabolite homovanillic acid (HVA) should change with drug withdrawal and change in clinical state."7.69Dopamine turnover in schizophrenia before and after haloperidol withdrawal. CSF, plasma, and urine studies. ( Beuger, M; Kelley, ME; van Kammen, DP; Yao, J, 1996)
"The efficacy of mianserin as a supplement in treating chronic schizophrenia was tested in 20 inpatients with schizophrenia who were receiving fixed doses of neuroleptics."7.68Effects of mianserin on negative symptoms in schizophrenia. ( Imai, T; Kai, S; Kajimura, N; Kaneyuki, H; Mizuki, Y; Suetsugi, M; Yamada, M, 1990)
"Measurement of plasma prolactin (PRL) concentration and plasma homovanillic acid (HVA) concentration was performed in 24 patients with schizophrenia during maintenance haloperidol treatment."7.68Plasma prolactin and homovanillic acid as markers for psychopathology and abnormal movements during maintenance haloperidol treatment in male patients with schizophrenia. ( Csernansky, JG; Newcomer, JW; Riney, SJ; Vinogradov, S, 1992)
"Large doses (960 to 3200 mg/day) of propranolol were taken by eight patients with chronic schizophrenia in a double-blind therapeutic trial."7.67Effect of propranolol on monoamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia. ( Linnoila, M; Ninan, PT; Scheinin, M; van Kammen, DP, 1984)
"Schizophrenic patients with high ventricle brain ratios and cortical brain atrophy, as shown by computerized tomography, had decreased spinal fluid concentrations of homovanillic acid and dopamine-beta-hydroxylase activity."7.66Dopamine-beta-hydroxylase activity and homovanillic acid in spinal fluid of schizophrenics with brain atrophy. ( Linnoila, M; Mann, LS; Marder, SR; Ninan, PT; Rieder, RO; Scheinin, M; Sternberg, DE; van Kammen, DP; van Kammen, WB, 1983)
"1."5.29Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia. ( Inanaga, K; Kuniyoshi, M; Miura, C; Nakamura, J, 1994)
"Raclopride was well tolerated."5.27An open label trial of raclopride in acute schizophrenia. Confirmation of D2-dopamine receptor occupancy by PET. ( Farde, L; Jansson, P; Sedvall, G; Uppfeldt, G; Wahlen, A; Wiesel, FA, 1988)
" In neither patient, the increase in haloperidol dosage affected paranoid symptoms."5.26[Use of haloperidol in high doses in schizophrenia. Clinical, biochemical and pharmacokinetic study]. ( Bianchetti, G; Cuche, H; Loo, H; Morselli, PL; Scatton, B; Zarifian, E, 1982)
" We investigated the effects of aripiprazole and blonanserin on clinical symptoms and plasma levels of homovanillic acid (pHVA) and 3-methoxy-4hydroxyphenylglycol in the switching strategy of schizophrenia."5.19Switching antipsychotics to aripiprazole or blonanserin and plasma monoamine metabolites levels in patients with schizophrenia. ( Kanno-Nozaki, K; Katsumi, A; Mashiko, H; Miura, I; Niwa, S; Shiga, T; Yabe, H, 2014)
"In the treatment of acute schizophrenia, risperidone and aripiprazole are both placed the first line antipsychotics."5.16Effect of switching to risperidone after unsuccessful treatment with aripiprazole on plasma monoamine metabolites level in the treatment of acute schizophrenia. ( Kanno, K; Katsumi, A; Mashiko, H; Miura, I; Niwa, S; Takeuchi, S; Watanabe, K, 2012)
"We investigated the effects of aripiprazole on plasma levels of brain-derived neurotrophic factor (BDNF) and catecholamine metabolites in first-episode untreated schizophrenia patients."5.16Aripiprazole altered plasma levels of brain-derived neurotrophic factor and catecholamine metabolites in first-episode untreated Japanese schizophrenia patients. ( Atake, K; Hayashi, K; Hori, H; Ikenouchi-Sugita, A; Katsuki, A; Nakamura, J; Tomita, M; Umene-Nakano, W; Yoshimura, R, 2012)
" We examined the effects of the Taq1A polymorphism on the plasma monoamine metabolites during the treatment of schizophrenia with aripiprazole, a DRD2 partial agonist."5.16Effects of aripiprazole and the Taq1A polymorphism in the dopamine D2 receptor gene on the clinical response and plasma monoamine metabolites level during the acute phase of schizophrenia. ( Kanno, K; Katsumi, A; Mashiko, H; Miura, I; Mori, A; Niwa, S; Numata, Y; Takeuchi, S; Yang, Q, 2012)
"An open-label study was performed to investigate the clinical efficacy and mechanisms of risperidone liquid in ameliorating positive symptoms in the acute phase of schizophrenia."5.11An open study of risperidone liquid in the acute phase of schizophrenia. ( Egami, H; Goto, M; Kaji, K; Kakihara, S; Kohara, K; Maeda, H; Nakamura, J; Ninomiya, H; Shinkai, K; Ueda, N; Yamada, Y; Yoshimura, R, 2005)
"This study tested the hypothesis that plasma homovanillic acid (pHVA) levels, a peripheral measure of central dopaminergic activity, would predict the change in memory performance in patients with schizophrenia treated with clozapine."5.11Prediction of changes in memory performance by plasma homovanillic acid levels in clozapine-treated patients with schizophrenia. ( Jayathilake, K; Kim, CH; Lee, MA; Meltzer, HY; Roy, A; Sumiyoshi, C; Sumiyoshi, T, 2004)
"Previous work suggests that individuals with schizophrenia display an altered homovanillic acid (HVA) response to metabolic stress."5.11Abnormal response to metabolic stress in schizophrenia: marker of vulnerability or acquired sensitization? ( Cavalier, E; Delespaul, P; Gielen, J; Marcelis, M; Van Os, J, 2004)
"We have previously reported that risperidone might improve negative symptoms in schizophrenia by influencing noradrenergic neurons."5.10Plasma levels of homovanillic acid and the response to risperidone in first episode untreated acute schizophrenia. ( Nakamura, J; Shinkai, K; Ueda, N; Yoshimura, R, 2003)
"We have investigated plasma homovanillic acid (pHVA) and 3-methoxy-4-hydroxyphenylglycol (pMHPG) concentrations in 34 DSM-III-R neuroleptic-treated schizophrenic patients who were classified into deficit (n = 14) and nondeficit (n = 20) forms of schizophrenia."5.08Plasma 3-methoxy-4-hydroxyphenylglycol and homovanillic acid measurements in deficit and nondeficit forms of schizophrenia. ( Dollfus, S; Dourmap, N; Ménard, JF; Petit, M; Ribeyre, JM; Thibaut, F, 1998)
"Ketamine (1) produced behaviors similar to the positive and negative symptoms of schizophrenia; (2) elicited alterations in perception; (3) impaired performance on tests of vigilance, verbal fluency, and the Wisconsin Card Sorting Test; (4) evoked symptoms similar to dissociative states; and (5) preferentially disrupted delayed word recall, sparing immediate recall and postdistraction recall."5.07Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. ( Bowers, MB; Bremner, JD; Charney, DS; Delaney, R; Freeman, GK; Heninger, GR; Karper, LP; Krystal, JH; Seibyl, JP, 1994)
"Twenty-one patients with schizophrenia who met criteria for neuroleptic treatment resistance or intolerance participated in a crossover, placebo-controlled, double-blind comparison of long-term typical neuroleptic and clozapine treatment."5.07Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine. ( Gutierrez, R; Konicki, E; Litman, RE; Owen, RR; Pickar, D; Rapaport, MH, 1992)
"Plasma prolactin concentration (pPRL), plasma homovanillic acid concentration (pHVA), and symptomatology were measured in 24 male subjects with schizophrenia during maintenance haloperidol treatment."5.07Plasma prolactin and homovanillic acid as markers for psychopathology and abnormal movements after neuroleptic dose decrease. ( Csernansky, JG; Newcomer, JW; Riney, SJ; Vinogradov, S, 1992)
"The introduction of the atypical neuroleptic, clozapine, has had widespread influence not only on the treatment of the seriously mentally ill patient, but also on new drug development and on hypotheses of the pathophysiology of schizophrenia."5.07Predictors of clozapine response in schizophrenia. ( Hsiao, JK; Litman, RE; Owen, RR; Pickar, D; Su, TP, 1994)
"Plasma homovanillic acid (HVA) levels were measured hourly for a 24-hour period in 10 patients with schizophrenia during treatment with placebo and fluphenazine."5.06Circadian variation of plasma homovanillic acid levels is attenuated by fluphenazine in patients with schizophrenia. ( Doran, AR; Douillet, P; Labarca, R; Pickar, D; Roy, A; Wolkowitz, OM, 1990)
"Previous studies have variably reported the efficacy of apomorphine in treatment of schizophrenia and tardive dyskinesia."5.05Apomorphine and schizophrenia. Treatment, CSF, and neuroendocrine responses. ( Davis, BM; Davis, KL; Horvath, TB; Kendler, KS; Levy, MI; Mathé, AA; Mohs, RC; Trigos, G, 1984)
"Four patients with chronic schizophrenia of stationary character were studied in order to titrate the lowest dose of thioridazine necessary for symptomatic control when the drug is given in combination with the inhibitor of catecholamine synthesis, metyrosine."5.04Potentiation by metyrosine of thioridazine effects in chronic schizophrenics. A long-term trial using double-blind crossover technique. ( Carlsson, A; Roos, BE; Skott, A; Wålinder, J, 1976)
"Metabolism of the monoamines dopamine, serotonin and noradrenaline, is altered in the central nervous system of people with schizophrenia, and their major metabolites homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (MHPG), respectively, have been intensively studied as indirect measures of these neurotransmitters in cerebrospinal fluid (CSF)."3.88No major influence of regular tobacco smoking on cerebrospinal fluid monoamine metabolite concentrations in patients with psychotic disorder and healthy individuals. ( Agartz, I; Andreou, D; Hjärpe, J; Jönsson, EG; Sedvall, GC; Söderman, E, 2018)
"Aripiprazole has been reported to exert variable effects on cognitive function in patients with schizophrenia."3.85Blood Biomarkers Predict the Cognitive Effects of Aripiprazole in Patients with Acute Schizophrenia. ( Atake, K; Beppu, H; Hori, H; Igata, R; Katsuki, A; Konishi, Y; Tominaga, H; Yoshimura, R, 2017)
" In the present study, we examined the association between blood levels of 3-methoxy-4-hydroxyphenylglycol (MHPG), homovanillic acid (HVA), or brain-derived neurotrophic factor (BDNF) and scores on the Wisconsin Card Sorting Test (WCST) in patients with early-stage schizophrenia."3.75Associations between plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) and negative symptoms or cognitive impairments in early-stage schizophrenia. ( Goto, N; Hayashi, K; Hori, H; Ikenouchi-Sugita, A; Kakeda, S; Korogi, Y; Moriya, J; Nakamura, J; Ueda, N; Umene-Nakano, W; Yoshimura, R, 2009)
"This study evaluates the relationship between plasma homovanillic acid (pHVA) levels, which have been used to study the role of central dopamine in schizophrenia, and the positive/negative syndrome in first episode schizophrenic patients before and after antipsychotic treatment."3.75Plasma homovanillic acid differences in clinical subgroups of first episode schizophrenic patients. ( Baeza, I; Bernardo, M; Castro-Fornieles, J; de la Serna, E; Deulofeu, R; Goti, J; Salvà, J, 2009)
" Effects of metabolic perturbation on plasma homovanillic acid in schizophrenia."3.73Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia. ( Bullmore, E; Hofman, P; Marcelis, M; Suckling, J; van Os, J; Woodruff, P, 2006)
"To study the role of dopamine neurotransmission in schizophrenia and its drug treatment by assessing the relationship of plasma homovanillic acid (pHVA), a major central dopamine metabolite to various clinical parameters in schizophrenic patients."3.71Relationship of symptomatology, gender, and antipsychotic drug treatment with plasma homovanillic acid in schizophrenia. ( Peet, M; Ramchand, C; Reynolds, GP; Shah, S; Zhang, ZJ, 2001)
"In this study, plasma obtained from monozygotic twin pairs discordant for schizophrenia (n = 10) or major affective disorder (n = 3) was assayed for epinephrine, norepinephrine, dihydroxyphenylacetic acid, homovanillic acid, adrencorticotropin hormone, and cortisol."3.71Plasma hormones and catecholamine metabolites in monozygotic twins discordant for psychosis. ( Bonsall, R; Walder, DJ; Walker, EF, 2002)
"The concentration of dopamine (DA) metabolite-homovanillic acid (HVA) in cerebrospinal fluid (CSF) of 40 patients with schizophrenia 27 with epilepsy and 15 controls without disorders of CNS was reported."3.70[Study on dopamine metabolite in cerebrospinal fluid of schizophrenics and epilepsics]. ( Chen, X; Jiang, S; Liao, W, 1998)
"Plasma homovanillic acid (HVA), the major DA metabolite and an indicator of brain DA activity, was measured in nonpsychotic, physically healthy first-degree relatives (n = 55) of schizophrenic probands and in normal subjects (n = 20) without a family history of schizophrenia."3.70Genetic antecedents of dopamine dysfunction in schizophrenia. ( Amin, F; Davis, KL; Knott, PJ; Siever, LJ; Silverman, JM; Smith, CJ, 1999)
"To examine plasma homovanillic acid (pHVA) levels in first-episode schizophrenia, to compare pHVA levels in patients and controls, and to assess the association of pHVA levels with psychopathology and treatment response."3.69Plasma homovanillic acid levels in first-episode schizophrenia. Psychopathology and treatment response. ( Alvir, J; Amin, F; Chakos, M; Cooper, T; Koreen, AR; Lieberman, J; Loebel, A; Mayerhoff, D, 1994)
"The dopamine hypotheses of schizophrenia and antipsychotic drug action suggest that the dopamine metabolite homovanillic acid (HVA) should change with drug withdrawal and change in clinical state."3.69Dopamine turnover in schizophrenia before and after haloperidol withdrawal. CSF, plasma, and urine studies. ( Beuger, M; Kelley, ME; van Kammen, DP; Yao, J, 1996)
"In a series of studies tyrosine transport was investigated in patients with schizophrenia."3.69Tyrosine transport as an indicator of cell membrane dysfunction in schizophrenia. ( Bjerkenstedt, L; Wiesel, FA, 1996)
"The relationship between pretreatment levels of plasma homovanillic acid (pHVA) and the outcome of clozapine treatment was studied in 18 male patients with schizophrenia who were resistant to treatment with conventional neuroleptics."3.69Prediction of short-term changes in symptom severity by baseline plasma homovanillic acid levels in schizophrenic patients receiving clozapine. ( Hasegawa, M; Jayathilake, K; Meltzer, HY; Sumiyoshi, T, 1997)
"In order to investigate the biological mechanisms underlying the clinical efficacy of clozapine, 200 mg/day of clozapine was added to the drug regimens of 19 patients with chronic, anti-psychotic-resistant schizophrenia, and the plasma homovanillic acid (HVA), clozapine concentrations, anti-dopamine D2 and anti-serotonin 5-HT2 receptor activities were measured."3.69Improvement of schizophrenic symptoms and changes in plasma HVA concentrations, plasma anti-D2 and anti-5-HT2 receptor activities with clozapine. ( Asai, M; Fang, YY; Kanba, S; Nibuya, M; Suzuki, E; Wang, ZC; Yagi, G; Yamada, K; Yan, HG, 1996)
"Plasma homovanillic acid concentration was assessed in 60 young schizophrenic patients, with and without first-degree relatives with schizophrenia, before treatment, and 3 days after starting haloperidol treatment."3.69Schizophrenia: gender, family risk, and plasma homovanillic acid. ( Andía, I; Basterreche, E; Dávila, R; Friedhoff, AJ; González-Torres, MA; Guimón, J; Zamalloa, MI; Zumárraga, M, 1995)
"Increased noradrenergic activity during chronic dopamine blockade may be an episode marker and may predict relapse within 6 weeks following haloperidol withdrawal in schizophrenia."3.69Noradrenergic activity and prediction of psychotic relapse following haloperidol withdrawal in schizophrenia. ( Agren, H; Gurklis, J; O'Connor, DT; Peters, JL; van Kammen, DP; Yao, JK, 1994)
"In the week prior to discontinuation of haloperidol treatment, global behavioral ratings and a lumbar puncture for cerebrospinal fluid monoamine metabolities were obtained in 88 patients with chronic schizophrenia."3.69Behavioral vs biochemical prediction of clinical stability following haloperidol withdrawal in schizophrenia. ( Gilbertson, MW; Gurklis, JA; Kelley, ME; Peters, JL; van Kammen, DP; Yao, JK, 1995)
"The dopamine metabolite, 3,4-dihydroxyphenylacetic acid (DOPAC), was found to be decreased in the anterior cingulate cortex of individuals with schizophrenia compared with normal controls."3.69Decreased DOPAC in the anterior cingulate cortex of individuals with schizophrenia. ( Casanova, MF; Karoum, F; Wyatt, RJ, 1995)
"In order to investigate the biological characteristics of deficit syndrome in schizophrenia (Carpenter et al 1988), we examined cerebroventricular ratios (CVRs) and plasma concentrations of homovanillic acid (HVA) in a group of schizophrenic inpatients with deficit syndrome (n = 20) and in a control group of age- and sex-matched schizophrenic inpatients without deficit syndrome (n = 20)."3.69Schizophrenic patients with deficit syndrome have higher plasma homovanillic acid concentrations and ventricular enlargement. ( Asai, M; Kanba, S; Kinoshita, N; Matsuo, Y; Nibuya, M; Sekiya, U; Shintani, F; Suzuki, E; Yagi, G, 1995)
"The concentrations of serum tyrosine, phenylalanine and tryptophan have been determined in 23 male neuroleptic-free patients with schizophrenia and 28 male healthy control subjects."3.69Low concentrations of serum tyrosine in neuroleptic-free schizophrenics with an early onset. ( Hemmings, GP; Ramchand, CN; Wei, J; Xu, H, 1995)
"Eleven acutely psychotic patients with schizophrenia or schizoaffective disorder underwent a 5-7 day drug-washout period (with lorazepam allowed) prior to participating in a 6-week controlled dose haloperidol trial."3.68Haloperidol response and plasma catecholamines and their metabolites. ( Alam, MY; Boshes, RA; Fitzgibbon, ME; Green, AI; Pappalardo, KM; Schildkraut, JJ; Tsuang, MT; Waternaux, C, 1993)
"Twenty recently admitted patients with mood-incongruent psychoses underwent 1) interviews with the Schedule for Affective Disorders and Schizophrenia for diagnostic evaluation and symptom profiles, 2) drug-free baseline measurements of CSF neurotensin and homovanillic acid, and 3) close monitoring of a therapeutic trial of haloperidol to determine latency of antipsychotic response."3.68Relation of CSF neurotensin concentrations to symptoms and drug response of psychotic patients. ( Bissette, G; Garver, DL; Nemeroff, CB; Yao, JK, 1991)
"Lateral ventricle enlargement in schizophrenia has been positively correlated with poor premorbid competence, negative symptoms, and poor treatment response and negatively correlated with concentrations of homovanillic acid (HVA), a dopaminergic metabolite."3.68Lateral ventricle-brain ratio and balance between CSF HVA and 5-HIAA in schizophrenia. ( Caudle, J; Eccard, M; Jewart, RD; Lewine, RR; Pollard, W; Risby, E; Risch, SC; Stipetic, M, 1991)
"The efficacy of mianserin as a supplement in treating chronic schizophrenia was tested in 20 inpatients with schizophrenia who were receiving fixed doses of neuroleptics."3.68Effects of mianserin on negative symptoms in schizophrenia. ( Imai, T; Kai, S; Kajimura, N; Kaneyuki, H; Mizuki, Y; Suetsugi, M; Yamada, M, 1990)
"In 8 cases of typical neuroleptic malignant syndrome (NMS), homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA), noradrenaline (NA), and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) levels in the cerebrospinal fluid (CSF) were assayed during both the active phase of NMS and after recovery."3.68Neuroleptic malignant syndrome: a study of CSF monoamine metabolism. ( Ishiguro, T; Nisijima, K, 1990)
"Measurement of plasma prolactin (PRL) concentration and plasma homovanillic acid (HVA) concentration was performed in 24 patients with schizophrenia during maintenance haloperidol treatment."3.68Plasma prolactin and homovanillic acid as markers for psychopathology and abnormal movements during maintenance haloperidol treatment in male patients with schizophrenia. ( Csernansky, JG; Newcomer, JW; Riney, SJ; Vinogradov, S, 1992)
"Plasma homovanillic acid (pHVA) levels were measured in 16 chronically ill patients with schizophrenia who also suffered from tardive dyskinesia, and in a group of 14 chronically ill patients with schizophrenia who did not have tardive dyskinesia."3.68Plasma HVA, tardive dyskinesia and psychotic symptoms in long-term drug-free inpatients with schizophrenia. ( Barbato, G; de Bartolomeis, A; Monteleone, P; Muscettola, G; Pickar, D, 1990)
" Lumbar cerebrospinal fluid (CSF) neurotransmitter metabolite levels for homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), and 3-methoxy-4-hydroxyphenyl glycol (MHPG) were determined in patients with schizophrenia and Alzheimer's disease."3.67Seasonal variations of human lumbar CSF neurotransmitter metabolite concentrations. ( Davis, KL; Losonczy, MF; Mohs, RC, 1984)
"Large doses (960 to 3200 mg/day) of propranolol were taken by eight patients with chronic schizophrenia in a double-blind therapeutic trial."3.67Effect of propranolol on monoamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia. ( Linnoila, M; Ninan, PT; Scheinin, M; van Kammen, DP, 1984)
"In 16 patients with chronic schizophrenia, cerebrospinal fluid (CSF) concentrations of homovanillic acid (HVA) showed a significant negative correlation with computed tomographic measures of brain third ventricle size."3.67Cerebrospinal fluid HVA, central brain atrophy, and clinical state in schizophrenia. ( Bowden, CL; Contreras, SA; Houston, JP; Javors, MA; Maas, JW; McIntyre, KL, 1986)
"5-Hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were measured in the lumbar cerebrospinal fluid of 57 drug-free female patients with DSM-III diagnoses of major unipolar or bipolar depression (n = 14), schizophrenic disorder (n = 18), alcohol dependence (n = 13) and a group of other disorders (n = 12)."3.66Amine metabolites and neuroendocrine responses related to depression and suicide. ( Arató, M; Banki, CM, 1983)
"5-Hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were measured in the spinal fluid of 45 women hospitalized in a psychiatric department for major depression (14 cases), schizophrenia (18 cases) and alcohol dependence (13 cases)."3.66Relationship between cerebrospinal fluid amine metabolites, neuroendocrine findings and personality dimensions (Marke-Nyman scale factors) in psychiatric patients. ( Arató, M; Banki, CM, 1983)
"Schizophrenic patients with high ventricle brain ratios and cortical brain atrophy, as shown by computerized tomography, had decreased spinal fluid concentrations of homovanillic acid and dopamine-beta-hydroxylase activity."3.66Dopamine-beta-hydroxylase activity and homovanillic acid in spinal fluid of schizophrenics with brain atrophy. ( Linnoila, M; Mann, LS; Marder, SR; Ninan, PT; Rieder, RO; Scheinin, M; Sternberg, DE; van Kammen, DP; van Kammen, WB, 1983)
"Baseline concentrations of homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA) and MHPG in the cerebrospinal fluid (CSF) were determined in 67 lobotomized and 30 non-lobotomized patients with chronic schizophrenia."3.66Monoamine metabolite levels in cerebrospinal fluid and brain atrophy in lobotomized schizophrenic patients. ( Hyyppä, S; Kampman, R; Myllylä, V; Ranta, P; Rimón, R; Roos, BE, 1979)
"The authors report cerebrospinal fluid (CSF) concentrations of five monoamine metabolites before and after probenecid administration in normal subjects and patients with depression and schizophrenia."3.66CSF monoamine metabolites in depression and schizophrenia. ( Anderson, PJ; Barchas, JD; Berger, PA; Davis, KL; Faull, KF; Kilkowski, J; Kraemer, H, 1980)
"The metabolites of serotonin, dopamine, and norepinephrine, 5-hydroxyindoleacetic acid (5HIAA), homovanillic acid (HVA), and 3-methoxy-4-hydroxy-phenylethylene glycol (MHPG), respectively, were studied in cerebrospinal fluid of patients with acute schizophrenia."3.65Cerebrospinal fluid amine metabolites in acute schizophrenia. ( Carpenter, WT; Fink, E; Goodwin, FK; Post, RM, 1975)
"26 patients with a paranoid-hallucinatory syndrome were treated with a fixed daily dose of haloperidol."3.65Clinical and biochemical parameters during neuroleptic treatment. I. Investigations with haloperidol. ( Ackenheil, M; Eben, E; Hippius, H; Rüther, E; Schilkrut, R, 1976)
"Treatment with olanzapine for 8 weeks improved both positive and negative symptoms of schizophrenia."2.73Effects of olanzapine on plasma levels of catecholamine metabolites, cytokines, and brain-derived neurotrophic factor in schizophrenic patients. ( Hori, H; Ida, Y; Ikenouchi, A; Mitoma, M; Nakamura, J; Yamada, Y; Yoshimura, R, 2007)
"D-cycloserine was readily absorbed and did not induce side-effects or changes in vital signs and mood scores."2.69The partial NMDA agonist D-cycloserine stimulates LH secretion in healthy volunteers. ( Blankenstein, MA; Gispen-de Wied, C; Kahn, RS; Lipsch, C; van Berckel, BN; van Ree, JM; Wynne, HJ, 1998)
"Treatment with haloperidol caused initial increases in urinary homovanillic acid (HVA) output that returned toward baseline by the 5th week."2.67Studies of catecholamine metabolism in schizophrenia/psychosis--II. ( Berman, N; Bowden, CL; Contreras, SA; Javors, MA; Maas, JW; Miller, AL; Seleshi, E; Weintraub, SE, 1993)
"Sulpiride was administered in three different daily dosages (starting with 400, 800 or 1200 mg) according to a double blind randomized administration schedule."2.66Monoamine metabolites and amino acids in serum from schizophrenic patients before and during sulpiride treatment. ( Alfredsson, G; Wiesel, FA, 1989)
" The plasma RHAL:HAL ratios on days 6 and 7 were higher than and positively correlated with those at Tmax after a single dose of HAL and were negatively correlated with the HAL:RHAL ratios at Tmax after a single dose of RHAL."2.66Pharmacodynamics and pharmacokinetics of haloperidol and reduced haloperidol in schizophrenic patients. ( Chang, WH; Chen, CT; Chen, TY; Hu, WH; Jann, MW; Lam, YW; Lin, SK; Yeh, EK, 1989)
"Sulpiride-treated patients with extrapyramidal side effects had significantly higher drug concentrations in serum."2.65Relationships between drug concentrations in serum and CSF, clinical effects and monoaminergic variables in schizophrenic patients treated with sulpiride or chlorpromazine. ( Alfredsson, G; Bjerkenstedt, L; Edman, G; Härnryd, C; Oxenstierna, G; Sedvall, G; Wiesel, FA, 1984)
"Schizophrenia is probably ascribed to perinatal neurodevelopmental deficits, and its onset might be affected by environmental factors."1.62Preventive role of regular low-intensity exercise during adolescence in schizophrenia model mice with abnormal behaviors. ( Hata, T; Hiraga, T; Koizumi, H; Mouri, A; Nabeshima, T; Oharomari, LK; Okamoto, M; Shima, T; Soya, H; Yook, JS, 2021)
"Some individuals with schizophrenia present with a dopamine supersensitivity state (DSS) induced by a long-term administration of excessive antipsychotics; this is recognized as dopamine supersensitivity psychosis (DSP)."1.62Reduction of dopamine and glycogen synthase kinase-3 signaling in rat striatum after continuous administration of haloperidol. ( Hashimoto, K; Hirose, Y; Iyo, M; Kanahara, N; Kimura, H; Kimura, M; Nangaku, M; Niitsu, T; Oda, Y; Shirayama, Y, 2021)
"Patients with schizophrenia have higher rates of mortality than the general population."1.37Early death and CSF monoamine metabolites in schizophrenia spectrum psychosis. ( Carlborg, A; Jokinen, J; Jönsson, EG; Nordström, AL; Nordström, P, 2011)
" Dosage of concurrent neuroleptics was fixed at least 3 weeks prior to the trial and was unchanged throughout the study period."1.29B-HT 920, a dopamine D2 agonist, in the treatment of negative symptoms of chronic schizophrenia. ( Inoue, T; Koyama, T; Matsubara, S; Ohmori, T; Yamashita, I, 1993)
"Schizophrenia is associated with multiple cognitive deficits which in turn may be related to abnormal dopamine (DA) function."1.29Neuropsychological correlates of central monoamine function in chronic schizophrenia: relationship between CSF metabolites and cognitive function. ( Apter, S; Davidson, M; Davis, KL; Harvey, PD; Kahn, RS; Keefe, RS; Mohs, RC; Neale, JM, 1994)
"1."1.29Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia. ( Inanaga, K; Kuniyoshi, M; Miura, C; Nakamura, J, 1994)
"These 85 subjects with nonorganic psychoses had been previously studied with respect to their response to neuroleptic treatment."1.28Characteristics of psychotic inpatients with high or low HVA levels at admission. ( Bowers, MB, 1991)
"Raclopride was well tolerated."1.27An open label trial of raclopride in acute schizophrenia. Confirmation of D2-dopamine receptor occupancy by PET. ( Farde, L; Jansson, P; Sedvall, G; Uppfeldt, G; Wahlen, A; Wiesel, FA, 1988)
"Debrisoquin is a drug that suppresses the peripheral formation of homovanillic acid without affecting the central formation."1.27Effects of debrisoquin and haloperidol on plasma homovanillic acid concentration in schizophrenic patients. ( Davidson, M; Davis, BM; Davis, KL; Freed, LB; Lesser, JC; Losonczy, MF; Mohs, RC; Mykytyn, VV; Powchik, P, 1987)
"Homovanillic acid accumulation was decreased in this group."1.26Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology. ( Peters, JG, 1979)
" In neither patient, the increase in haloperidol dosage affected paranoid symptoms."1.26[Use of haloperidol in high doses in schizophrenia. Clinical, biochemical and pharmacokinetic study]. ( Bianchetti, G; Cuche, H; Loo, H; Morselli, PL; Scatton, B; Zarifian, E, 1982)
"Thioridazine was administered to 14 patients diagnosed as within the "schizophrenic spectrum" with the result that substantial improvement in psychotic symptoms was achieved while significant extrapyramidal side effects occurred in only 1 patients."1.25Thioridazine: central dopamine turnover and clinical effects of antipsychotic drugs. ( Bowers, MB, 1975)

Research

Studies (410)

TimeframeStudies, this research(%)All Research%
pre-1990203 (49.51)18.7374
1990's146 (35.61)18.2507
2000's35 (8.54)29.6817
2010's20 (4.88)24.3611
2020's6 (1.46)2.80

Authors

AuthorsStudies
Wang, XP1
Zhang, YY1
Lu, TL1
Lu, Z1
Kang, ZW1
Sun, YY1
Yue, WH1
Hori, H8
Yoshimura, R12
Katsuki, A4
Atake, K4
Takase, M1
Kimura, H2
Kanahara, N2
Nakata, Y1
Iyo, M2
Shiga, T3
Horikoshi, S3
Kanno, K3
Kanno-Nozaki, K4
Hikita, M1
Itagaki, S2
Miura, I7
Yabe, H5
Koizumi, H1
Hiraga, T1
Oharomari, LK1
Hata, T1
Shima, T1
Yook, JS1
Okamoto, M1
Mouri, A1
Nabeshima, T2
Soya, H1
Kimura, M1
Oda, Y1
Nangaku, M1
Hirose, Y1
Niitsu, T1
Shirayama, Y1
Hashimoto, K1
Hatakeyama, T1
Kunii, Y1
Kono, S1
Oshima, S1
Nozaki, K1
Suzuki, R1
Hjärpe, J1
Söderman, E2
Andreou, D2
Sedvall, GC3
Agartz, I2
Jönsson, EG4
da Silva Alves, F1
Bakker, G1
Schmitz, N1
Abeling, N1
Hasler, G1
van der Meer, J1
Nederveen, A1
de Haan, L1
Linszen, D1
van Amelsvoort, T1
Katsumi, A3
Mashiko, H5
Niwa, S6
Hino, M1
Ota, T1
Watanabe, K2
Igata, R2
Konishi, Y2
Nakamura, J11
Comasco, E1
Vumma, R1
Toffoletto, S1
Johansson, J1
Flyckt, L1
Lewander, T1
Oreland, L2
Bjerkenstedt, L10
Terenius, L3
Venizelos, N1
Beppu, H1
Tominaga, H1
Winter, C1
Djodari-Irani, A1
Sohr, R1
Morgenstern, R1
Feldon, J1
Juckel, G1
Meyer, U1
Baeza, I1
Castro-Fornieles, J1
Deulofeu, R1
de la Serna, E1
Goti, J1
Salvà, J1
Bernardo, M1
Arrúe, A4
Dávila, R13
Zumárraga, M11
Basterreche, N4
González-Torres, MA4
Goienetxea, B1
Zamalloa, MI3
Anguiano, JB3
Guimón, J6
Goto, N2
Kakeda, S2
Moriya, J2
Hayashi, K3
Ikenouchi-Sugita, A4
Umene-Nakano, W4
Ueda, N7
Korogi, Y2
Nikisch, G2
Baumann, P2
Kiessling, B2
Reinert, M1
Wiedemann, G2
Kehr, J2
Mathé, AA6
Piel, M1
Roesch, F1
Weisser, H2
Schneider, P1
Hertel, A2
Carlborg, A1
Jokinen, J1
Nordström, AL1
Nordström, P1
Yoshitake, T1
Dávila, W1
Inchausti, L1
Pérez-Cabeza, L1
Fernández-Rivas, A1
Bustamante, S1
Takeuchi, S2
Mori, A1
Yang, Q1
Numata, Y1
Tomita, M1
Kucinski, A1
Syposs, C1
Wersinger, S1
Bencherif, M1
Stachowiak, MK2
Stachowiak, EK2
Aymard, N3
Viala, A2
Clement, MN1
Jacquot, M1
Vacheron, MN1
Gauillard, J1
Caroli, F2
Oranje, B1
Gispen-de Wied, CC2
Verbaten, MN1
Kahn, RS15
Oades, RD2
Klimke, A1
Henning, U1
Rao, ML2
Kurachi, M5
Shinkai, K4
Kaneda, Y1
Ohmori, T2
Elman, I1
Lukas, S1
Shoaf, SE1
Rott, D1
Adler, C1
Breier, A14
van der Heijden, FM1
Tuinier, S1
Fekkes, D1
Sijben, AE1
Verhoeven, WM4
Sumiyoshi, T7
Roy, A12
Kim, CH1
Jayathilake, K3
Lee, MA1
Sumiyoshi, C1
Meltzer, HY3
Marcelis, M2
Cavalier, E1
Gielen, J1
Delespaul, P1
Van Os, J4
Kakihara, S2
Matsumoto, C1
Goto, M2
Kaji, K2
Yamada, Y3
Ohmori, O1
Kohara, K1
Ninomiya, H1
Egami, H1
Maeda, H1
Jacobsen, JP1
Rodriguiz, RM1
Mørk, A1
Wetsel, WC1
Duncan, E3
Bollini, AM1
Sanfilipo, M3
Wieland, S3
Angrist, B4
Cooper, TB4
Rotrosen, J4
Klejbor, I1
Myers, JM1
Hausknecht, K1
Corso, TD1
Gambino, AS1
Morys, J1
Maher, PA1
Hard, R1
Richards, J1
Suckling, J1
Hofman, P1
Woodruff, P1
Bullmore, E1
Ikenouchi, A1
Mitoma, M1
Ida, Y1
Zabalo, MJ2
Brunelin, J2
D'amato, T2
Dalery, J1
Suaud-Chagny, MF2
Saoud, M2
Cochet, A1
Toru, M4
Ichikawa, H1
Chen, YF2
DeLisi, LE1
Mirsky, AF1
Buchsbaum, MS1
van Kammen, DP19
Berman, KF2
Caton, C1
Kafka, MS1
Ninan, PT5
Phelps, BH1
Karoum, F7
Krupenina, LB1
Vinogradov, MV1
Lideman, RR1
Zlobina, GP1
Mukhin, AG1
Bowers, MB20
Heninger, GR6
Joseph, MH1
Waddington, JL1
Haracz, JL1
Owen, F3
Baker, HF1
Ridley, RM1
Cross, AJ2
Crow, TJ5
Tripodianakis, J1
Markianos, M3
Garelis, E2
Mann, LS2
Sternberg, DE2
Scheinin, M6
Marder, SR3
van Kammen, WB6
Rieder, RO1
Linnoila, M15
Domino, EF1
Leckman, JF2
Cohen, DJ2
Shaywitz, BA2
Caparulo, BK1
Wode-Helgodt, B5
Sedvall, G19
Gomes, UC1
Shanley, BC1
Potgieter, L1
Roux, JT1
Sturges, JS1
Gamaleia, NB2
Misionzhnik, EIu1
Vertogradova, OP1
Krasnov, VN1
Salenko, BB1
Nemtsov, AV1
Kalinin, VV1
Wood, PL1
Etienne, P1
Lal, S1
Gauthier, S1
Cajal, S1
Nair, NP1
King, DJ2
Cooper, SJ2
Liddle, J1
Banki, CM5
Arató, M7
Papp, Z4
Kurcz, M1
Levy, MI3
Davis, BM8
Mohs, RC12
Trigos, GC1
Davis, KL22
Magnusson, O1
Fowler, CJ1
Ross, SB2
Schulman, A2
Wetterberg, L1
Bartfai, A2
Levander, SE2
Nybäck, H3
Berggren, BM1
Hindmarsh, T1
Wiesel, FA12
Waters, RN1
Chang, WH8
Bartko, J1
Cowdry, RW1
Ebert, MH1
Post, RM6
Goodwin, FK7
Javaid, JI8
Liu, TS1
Maas, JW9
Davis, JM8
Alfredsson, G2
Edman, G3
Härnryd, C5
Oxenstierna, G3
Gullberg, B4
Jeste, DV2
Doongaji, DR1
van Ree, JM2
Westenberg, HG4
Krul, JM1
Brouwer, GJ1
Thijssen, JH1
de Wied, D1
van Praag, HM2
Ceulemans, DL1
Schalling, D1
Losonczy, MF5
Iselius, L1
Gerner, RH1
Fairbanks, L1
Anderson, GM1
Young, JG1
Hare, TA1
Zimmer, R1
Teelken, AW1
Cramer, H1
Ackenheil, M5
Zander, KJ1
Fischer, H1
Kendler, KS4
Trigos, G2
Horvath, TB5
Pickar, D26
Labarca, R7
Hommer, D2
Everett, D1
Paul, SM7
Charney, DS3
Karson, CN1
Kleinman, J1
Johns, CA2
Swigar, ME1
Jatlow, PI4
Goicoechea, N1
Lautin, A1
Stanley, M3
Gershon, S3
Heckl, K1
Karobath, M1
Anokhina, IP2
Kogan, BM1
Cutler, NR1
Wyatt, RJ6
Scatton, B1
Zarifian, E1
Bianchetti, G1
Cuche, H1
Loo, H3
Morselli, PL1
Kobayashi, K2
Koide, Y1
Shohmori, T3
Schiff, SR1
Shibuya, H1
Nishikawa, T1
Semba, J1
Mataga, N1
Takashima, M1
Berger, PA2
Faull, KF9
Kilkowski, J2
Anderson, PJ2
Kraemer, H2
Barchas, JD2
Andía, I7
Basterreche, E1
Friedhoff, AJ5
Faustman, WO6
Ringo, DL2
Agren, H2
Yao, JK8
O'Connor, DT2
Gurklis, J1
Peters, JL4
Harvey, PD3
Davidson, M20
Keefe, RS2
Apter, S8
Neale, JM1
de las Cuevas Castresana, C1
González de Rivera, JL1
Kuniyoshi, M1
Miura, C1
Inanaga, K1
Breslin, NA1
Suddath, RL1
Bissette, G2
Nemeroff, CB2
Lowrimore, P1
Weinberger, DR3
Owen, RR3
Litman, RE3
Hsiao, JK3
Su, TP1
Szymanski, S2
Lieberman, J3
Pollack, S2
Munne, R1
Safferman, A1
Kane, J3
Kronig, M1
Cooper, T5
Kitaichi, K1
Yamada, K3
Hasegawa, T1
Furukawa, H1
Risch, SC4
Csernansky, JG9
Newcomer, JW3
Jackson, K1
Lombrozo, L2
Zipursky, R1
Pfefferbaum, A2
Kelley, ME4
Gurklis, JA2
Gilbertson, MW3
Casanova, MF1
Nibuya, M5
Kanba, S6
Sekiya, U2
Suzuki, E5
Matsuo, Y1
Kinoshita, N3
Shintani, F3
Yagi, G6
Asai, M5
Elliott, PJ1
Knott, P5
Stern, RG4
Colison, J2
Bartko, JJ1
Doran, AR10
Konicki, PE4
Potter, WZ5
Manji, HK1
Lewine, RR3
Lieberman, JA2
Alvir, JM1
Mayerhoff, D2
Loebel, A2
Geisler, S2
Chakos, M2
Koreen, A1
Jody, D1
Wei, J3
Xu, H1
Ramchand, CN2
Hemmings, GP3
Amin, F5
Schmeidler, J1
Stern, R1
Knott, PJ2
Seiler, W1
Wetzel, H1
Hillert, A1
Schöllnhammer, G1
Benkert, O1
Hiemke, C1
Alvir, J2
Ramos-Lorenzi, J1
Woerner, M1
Novacenko, H1
Kane, JM1
Wolkin, A2
Röpcke, B1
Eggers, C1
Möller, HJ1
Adachi, S1
Koreen, AR1
Ribeyre, JM4
Lesieur, P2
Varoquaux, O2
Dollfus, S4
Pays, M1
Petit, M4
Lin, SK5
Chung, MC1
Lam, YW2
Jann, MW3
Waldo, MC1
Cawthra, E2
Adler, LE5
Dubester, S1
Staunton, M2
Nagamoto, H3
Baker, N3
Madison, A1
Simon, J1
Scherzinger, A1
Koyama, T1
Inoue, T1
Matsubara, S1
Yamashita, I1
Xu, HM1
Sharma, RP5
Janicak, PG4
Faull, K3
Miller, AL4
Contreras, S1
Seleshi, E6
True, JE1
Bowden, C1
Castiglioni, J1
Rapaport, MH2
Wolkowitz, O2
Kelsoe, JR1
Pato, C1
Krystal, JH1
Karper, LP1
Seibyl, JP1
Freeman, GK1
Delaney, R1
Bremner, JD1
Tuckwell, HC1
Koziol, JA1
Hwu, HG1
Chen, TY5
Lung, FW3
Chen, H1
Lin, WL4
Hu, WH5
Lin, HN1
Chien, CP1
Risby, ED1
Jewart, RD2
Stipetic, M2
McDaniel, JS1
Caudle, J2
Whelton, CL1
Gupta, RN1
Cleghorn, JM1
Ballagh, SR1
Davis, OR1
Buchanan, RW1
Moricle, LA1
Munson, RC1
Magliozzi, JR1
Gietzen, DW1
Olson, AM1
Maclin, EL1
Tuason, VB1
Green, AI2
Alam, MY2
Boshes, RA1
Waternaux, C2
Pappalardo, KM2
Fitzgibbon, ME1
Tsuang, MT1
Schildkraut, JJ2
Steinberg, JL1
Garver, DL6
Moeller, FG1
Raese, JD1
Orsulak, PJ1
Silva, H1
Jerez, S1
Ruiz, A1
Forray, MI1
Gysling, K1
Andres, ME1
Bustos, G1
Castillo, Y1
Hono, J1
Contreras, SA6
Berman, N3
Bowden, CL7
Javors, MA4
Weintraub, SE1
Weintraub, S1
Sobieraj, JT1
Salzman, C1
Schatzberg, AF1
Hirschowitz, J2
Juang, DJ1
Chen, LC1
Yang, CH1
Lane, HY1
Gonzalez, MA1
Silva, RR1
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Tsuchida, K1
Kanzaki, A1
Ujike, H1
Hamamura, T1
Kondo, K1
Mutoh, S1
Miyanagi, K1
Kuroda, S1
Otsuki, S2
Stein, I1
Prell, GD1
Green, JP1
Elkashef, AM1
Khandelwal, JK1
Lawson, WB1
Jaeger, AC1
Kaufmann, CA1
Kirch, DG3
Fukuda, M1
Hiramatsu, K1
Hata, A1
Nakagome, K1
Iwanami, A1
Honda, H1
Beuger, M2
Yao, J4
Northoff, G1
Wenke, J1
Demisch, L1
Eckert, J1
Gille, B1
Pflug, B1
Epstein, JI1
Roitman, SL1
Inosaka, T1
Saito, H1
Sato, M2
Koshikawa, H2
Donnelly, CL1
McEvoy, JP1
Wilson, WH1
Narasimhachari, N2
Hasegawa, M2
Funderburg, LG1
Weintraub, ST1
Thibaut, F2
Dourmap, N2
Meloni, R1
Laurent, C1
Campion, D1
Ménard, JF3
Mallet, J1
Ottong, SE1
Ohnishi, K1
Ashikari, I1
Wang, ZC1
Fang, YY1
Yan, HG1
Brown, AS1
Gewirtz, G1
Harkavy-Friedman, J1
Brébion, G1
Amador, XF1
Malaspina, D1
Gorman, JM1
Bulbena, A1
Galinowski, A2
Poirier, MF2
Leyris, A1
Beauverie, P1
Bourdel, MC1
Geijer, T1
Gyllander, A1
van Berckel, BN1
Lipsch, C1
Gispen-de Wied, C1
Wynne, HJ1
Blankenstein, MA1
Hatzimanolis, J1
Lykouras, L1
Oulis, P1
Wieselgren, IM2
Lindström, LH5
Nagamoto, HT1
McRae, KA1
Huettl, P1
Gerhardt, G2
Hea, R1
Griffith, J1
Saitoh, O2
Yotsutsuji, T2
Itoh, H3
Kurokawa, K2
Silverman, JM1
Siever, LJ1
Smith, CJ1
Soares, JC1
Innis, RB1
Jiang, S1
Chen, X1
Liao, W1
Uehara, T2
Tanii, Y1
Chotai, J1
Salander Renberg, E1
Kullgren, G1
Asberg, M1
Kim, YK1
Kim, L1
Lee, MS1
Holcomb, JA1
Christensen, JD1
Balla, A1
Koneru, R1
Smiley, J1
Sershen, H1
Javitt, DC1
Scheepers, FE1
Zhang, ZJ1
Reynolds, GP2
Ramchand, C1
Peet, M1
Shah, S1
Walker, EF1
Bonsall, R1
Walder, DJ1
Curzon, G2
Kantamaneni, BD2
Bartlett, JR2
Bridges, PK2
Watanabe, S1
Kaneno, S1
Lindström, L1
Johnstone, EC3
Longden, A3
Bacopoulos, NC1
Spokes, EG2
Bird, ED2
Roth, RH1
Nagao, T1
Ohshimo, T1
Mitsunobu, K1
Deakin, JF1
Westerink, BH1
Korf, J1
Wilk, S3
Clow, A1
Jenner, P1
Theodorou, A1
Marsden, CD1
Angrist, BM1
Aronson, M1
Gruen, P1
Sachar, EJ1
Denning, RK1
Matthysse, S3
Grimm, VE1
Roccatagliata, G1
Albano, C1
Cocito, L1
Maffini, M1
Moore, D1
Tarsy, D1
Study, RE1
Bunney, W1
Gillin, JC1
Jimerson, D1
Van Kammen, D2
Peters, JG1
Rimón, R1
Roos, BE4
Kampman, R1
Hyyppä, S1
Ranta, P1
Myllylä, V1
Winblad, B1
Bucht, G1
Gottfries, CG2
Iversen, LL1
Mackay, AV1
Riley, GJ1
Shimizu, T1
Murphy, DL1
Bunney, WE2
Wålinder, J3
Skott, A2
Carlsson, A3
Wallin, L1
Fyrö, B3
Hoehn, MM1
Crowley, TJ1
Rutledge, CO1
Kirstein, L1
Heninger, G1
Rüther, E1
Schilkrut, R1
Eben, E1
Hippius, H2
Sepping, P1
Zabrodin, GD1
Turova, ZG1
Gerlach, J2
Thorsen, K1
Fog, R1
Subrahmanyam, S1
Fink, E1
Carpenter, WT1
Jimerson, DC1
Gordon, EK1
Bilder, RM1
Keefe, R1
Webster, L1
Whiteford, HA1
Stedman, TJ1
Welham, J1
Pond, SM1
Ohlund, LS1
Ohman, A1
Konicki, E1
Gutierrez, R1
Botsis, A1
Arvanitis, Y1
Heritch, AJ1
Volavka, J1
Douyon, R1
Convit, A1
Czobor, P1
Waldo, M3
Drebing, C3
Adler, L1
Freedman, R4
Mazure, CM3
Nelson, JC3
Riney, SJ2
Vinogradov, S2
Pandey, GN2
Powchik, P4
Warne, P1
Kaminsky, R3
Jaff, S2
Baker, NJ2
Bell, J1
Hattox, S1
Murphy, R1
Ishizuki, T1
Kohno, H1
Nakaki, T1
Ko, G1
Peters, J4
Neylan, T2
Shaw, D1
Nisijima, K1
Ishiguro, T1
Degrell, I2
Nagy, E1
Wolkowitz, OM11
Pato, CN1
Mizuki, Y1
Kajimura, N1
Imai, T1
Suetsugi, M1
Kai, S1
Kaneyuki, H1
Yamada, M1
King, RJ2
Moses, JA3
Poscher, ME1
Klockhoff, I1
Svedberg, A1
Jibson, M1
Risby, E1
Eccard, M1
Pollard, W1
Wik, G1
Pontius, E1
Gregoire, A1
Cooper, M1
DuMont, K1
Benson, KL1
Zarcone, VP1
Den Boer, JA2
Ravelli, DP1
Huisman, J1
Ohrvik, J1
Khan, RS1
Goldstein, M2
Kerman, B1
Easton, M1
Kaminski, R1
Powchick, P2
Warne, PA1
McQueeney, RT1
Petrie, EC1
Muscettola, G1
Barbato, G1
de Bartolomeis, A1
Monteleone, P1
Beinfeld, MC1
Yeh, EK4
Gerhardt, GA2
Franks, R1
Douillet, P2
Ninan, P1
Mazonson, A1
Hagenfeldt, L1
Jennings, WS1
Schulz, SC1
Hamer, RM1
Friedel, RO1
Imazu, Y1
Kawabata, M1
Song, IS1
Saito, T1
Ishizawa, H1
Tsuchiya, F1
Ozawa, H1
Takahata, N1
Besev, G1
Gunne, LM1
Brown, GL1
Doran, A2
Parnetti, L1
Gottfries, J1
Karlsson, I1
Långström, G1
Svennerholm, L1
Swahn, CG1
Leahey, W1
Green, DF1
Widerlöv, E1
Lu, RB1
Ko, HC1
Lin, YT1
Ho, SL1
Rosen, J1
McAdam, D1
Nugent, A1
Goetz, KL1
Johns, C1
Rubinow, DR1
Glazer, WM1
Lee, CF2
Lee, TC1
Frecska, E4
Bagdy, G4
Perenyi, A4
Mogyorosy, Z1
Vojnik, M1
Balla, KZ1
Boronow, J2
Révai, K3
Fekete, MI1
Ko, GN1
Zhang, LD1
Yan, WW1
Manero, E2
Retuerto, F1
Barcena, B1
Garcia, A1
Guicheney, P1
Mignot, E1
Meyer, P1
Sharma, R2
Janicak, P2
Comaty, J2
Chen, CT1
Van Putten, T1
Aravagiri, M1
Chabert, N1
Mintz, J1
Rapaport, M1
Ferrier, IN1
Johnson, JA1
Owens, DG1
Poulter, M1
Awad, AG1
Müller-Spahn, F1
Zemlan, FP1
Hitzemann, RJ1
Syvälahti, EK1
Hietala, J2
Huupponen, R1
Pihlajamäki, K1
Seppälä, OP1
Säkö, E1
Morimasa, T1
Jaskiw, G1
Kelsoe, J1
Heh, CW1
Potkin, SG1
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Herrera, J1
Sramek, J1
DeMet, E1
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Uppfeldt, G1
Wahlen, A1
Schweitzer, JW1
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Hoffmann, G2
Markianos, E2
Nyström, I1
Raese, J2
Sathananthan, G1
Fri, CG2
Rosenblatt, S1
Leighton, WP1
Chanley, JD1
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Greil, W1

Clinical Trials (15)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Lurasidone Vs Olanzapine on Neurotrophic Biomarkers and Cardiometabolic Parameters in First Episode Untreated Schizophrenia: A Randomized, Open Label, Active Controlled Study[NCT03304457]Phase 4100 participants (Actual)Interventional2017-08-25Completed
Prematurity as Predictor of Children's Cardiovascular-renal Health (PREMATCH)[NCT02147457]180 participants (Actual)Observational2014-10-31Completed
[NCT00004325]200 participants Observational1988-12-31Completed
Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776]Phase 254 participants (Actual)Interventional2017-08-07Completed
A Randomized Trial Administering Estradiol Patch vs. Placebo Patch as add-on to Antipsychotics in Female Patients Above the Age of 38 With Schizophrenia, Schizoaffective or Schizophreniform Disorder[NCT04093518]Phase 3100 participants (Anticipated)Interventional2019-12-02Recruiting
Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder[NCT03748446]Early Phase 120 participants (Anticipated)Interventional2019-12-05Recruiting
Efficacy of Rapid-Acting NMDA Antagonist for Treatment of Adolescent Depression and Anxiety Disorders[NCT02579928]Phase 417 participants (Actual)Interventional2015-10-31Completed
Measurement of GABA and Neurosteroid Levels in Women With Menopausal Major Depression Before and After Treatment With Estrogen Alone, Fluoxetine Alone, or Estrogen and Fluoxetine and Normal Controls Before and After Treatment With Estrogen[NCT00626340]Phase 418 participants (Actual)Interventional1999-07-31Completed
Changes of the Short Portable Mental Status Questionnaire (SPMSQ-E) After Ketamine Administration on Ophthalmic Surgery in Geriatric Population.[NCT02049411]Phase 280 participants (Actual)Interventional2013-06-30Completed
Biomarkers of Conversion Risk and Treatment Response in Early-Stage Schizophrenia[NCT03323437]Phase 447 participants (Actual)Interventional2017-09-15Completed
Ketamine for Severe Adolescent Depression: Intermediate-term Safety and Efficacy[NCT03889756]Phase 2/Phase 33 participants (Actual)Interventional2019-07-17Terminated (stopped due to No more funding available to continue since we could not recruit throughout the pandemic.)
Clozapine Response and Biogenic Amines in Schizophrenia[NCT00169039]Phase 466 participants Interventional1994-12-31Terminated
Efficacy of Quetiapine in Treating Patients With Active Substance Use Disorder and Schizophrenia[NCT00156715]Phase 423 participants (Actual)Interventional2004-03-31Completed
Aripiprazole Effects on Reward Processing in Deficit Syndrome Schizophrenia[NCT00209027]20 participants (Actual)Interventional2005-04-30Terminated (stopped due to difficulty with technical aspect of fMRI, resources to complete the study ran out)
Risperidone Long-Acting for Alcohol and Schizophrenia Treatment (R-LAST)[NCT00130923]Phase 495 participants (Actual)Interventional2005-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Prefrontal GABA+ Concentrations

Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine3.90
Gabapentin3.93
Placebo Oral Tablet3.73

Prefrontal Glx Concentrations

Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine21.59
Gabapentin21.69
Placebo Oral Tablet22.25

Montgomery-Asberg Depression Rating Scale Score 1 Day After Infusion

"Depressive symptoms (measured by Montgomery-Asberg Depression Rating Scale, revised (MADRS) score) on 1 day after infusion, for the cohort of subjects enrolled in the MDD arm of this trial.~Higher MADRS score indicates more severe depression, and each item yields a score of 0 to 6. The overall score ranges from 0 to 60.~Usual cutoff points are:~0 to 6 - normal /symptom absent. 7 to 19 - mild depression. 20 to 34 - moderate depression. >34 - severe depression." (NCT02579928)
Timeframe: 1 day after the infusion

Interventionunits on a scale (Mean)
Ketamine15.44
Midazolam24.13

Comparison of Cortical GABA Levels in 4 Groups of Subjects Using Estrogen Alone, Fluoxetine Alone, Estrogen and Fluoxetine Combined in Pre and Post 4.0T Magnetic Resonance Spectroscopy Sessions.

"This study was conducted at Yale University almost two decades ago. Our group at the University of Pennsylvania only has very basic information about this study. This includes the number of participants, which was 18, and the fact that no adverse events occurred. Staff members at the University of Pennsylvania do not have access to any additional study data. The contact person who initially entered this study protocol information is no longer at the University of Pennsylvania and we are unable to contact for additional information.~We only know that 18 participants completed, but as far as we know data was never analyzed for these 18 participants." (NCT00626340)
Timeframe: Healthy controls will undergo scans pre and post 3 weeks of estrogen treatment. Women with depression will undergo scans pre and post 6 weeks of treatment with estrogen alone, estrogen and fluoxetine, or fluoxetine alone

Intervention ()
All Participants0

Efficacy of a Multiple-dosing Ketamine Infusion Paradigm (2 Infusions Per Week for 3 Weeks) Compared to Midazolam in Adolescents With Treatment Resistant Depression Using the Children's Depression Rating Scale (CDRS)

Establish if repeated ketamine will be efficacious medically and psychiatrically, as measured by a significant reduction in CDRS score in those treated with ketamine at the end of the dosing paradigm. The Children's Depression Rating Scale (CDRS) is a clinician-rated instrument with 17 items scored on a 1 to 5 or 1 to 7 scale. A rating of 1 indicates normal, thus the minimum score is 17. The maximum score is 113. Scores of 20-30 suggest borderline depression. Scores of 40-60 indicate moderate depression. (NCT03889756)
Timeframe: Day 18

Interventionscore on a scale (Mean)
Ketamine42
Midazolam62

Tolerability of a Multiple-dosing Ketamine Infusion Paradigm (2 Infusions Per Week for 3 Weeks) Compared to Midazolam in Adolescents With Treatment Resistant Depression

Establish if repeated ketamine will be tolerated as measured by drop-out counts. (NCT03889756)
Timeframe: Day 18

InterventionParticipants (Count of Participants)
Ketamine0
Midazolam0

Clinical Symptoms

The main outcome measure of clinical symptoms was the Positive and Negative Symptoms Scale. This is a 30 item scale for assessing patients diagnosed with schizophrenia. Each item is rated on a 1 (absent) to 7 (extreme) scale. The minimum total score is 30 and the maximum is 210. (NCT00156715)
Timeframe: 12 Weeks

InterventionUnits on a scale (Mean)
QUET65.5

Mean Number of Drinking Days Per Week

Timeline Follow-back (TLFB) procedure was used at screening and baseline to establish current substance use, and it was also used weekly during the course of the study to assess continued alcohol and other substance use. TLFB cosisted of using a calendar and sasking participants to report alcohol and other drug use since last visit. At the screening visit, the TLFB was done for the four weeks prior to the visit. (NCT00156715)
Timeframe: 12 Weeks

InterventionDrinking Days per Week (Mean)
QUET2.7

Average Over Time of Frequency of Drinking Days (Used to Evaluate Treatment Efficacy)

Frequency of drinking days is obtained each week retrospectively as the number of drinking days during the prior week (assessed using the Timeline Followback). Mixed models are used to obtain estimates of efficacy from the partial data provided by each subject while adherent to assigned treatment (under the 'missing at random' assumption). The 'explanatory' estimands (target of the mixed model estimation) are defined in terms of population quantities that would have occurred had all subjects remained on assigned treatment throughout the study. The point estimate for each arm is reported under Number. (NCT00130923)
Timeframe: 6 months

Interventiondrinking days per week (Number)
Risperidone Long Acting Injectable (LAI)2.84
Oral Risperidone Aka Risperdal3.46

Average Over Time of Global Functioning (Used to Evaluate Treatment Efficacy)

A rater assesses social, occupational and psychological functioning on a hypothetical continuum of mental health - illness (using Global Assessment of Functioning); scores range from 100 to 1, where higher values represent a better outcome. Mixed models are used to obtain estimates of efficacy from the partial data provided by each subject while adherent to assigned treatment (under the 'missing at random' assumption). The 'explanatory' estimands (target of the mixed model estimation) are defined in terms of population quantities that would have occurred had all subjects remained on assigned treatment throughout the study. The point estimate for each arm is reported under Number. (NCT00130923)
Timeframe: 6 months

Interventionordinal severity of impairment (Number)
Risperidone Long Acting Injectable (LAI)50.8
Oral Risperidone Aka Risperdal49.9

Average Over Time of Positive and Negative Symptoms (Used to Evaluate Treatment Efficacy)

A rater assesses positive and negative symptoms of schizophrenia using a 30-item scale (Positive and Negative Symptom Score) Scores range from 30 to 210, where higher values represent a worse outcome. Mixed models are used to obtain estimates of efficacy from the partial data provided by each subject while adherent to assigned treatment (under the 'missing at random' assumption). The 'explanatory' estimands (target of the mixed model estimation) are defined in terms of population quantities that would have occurred had all subjects remained on assigned treatment throughout the study. The point estimate for each arm is reported under Number. (NCT00130923)
Timeframe: 6 months

Interventionordinal severity of symptoms (Number)
Risperidone Long Acting Injectable (LAI)78.2
Oral Risperidone Aka Risperdal75.5

Average Over Time of Severity of Illness and Global Improvement (Used to Evaluate Treatment Efficacy)

A rater assesses the severity of illness and global impression using a scale from 1 to 7 (Clinical Global Impression), where higher values represent a worse outcome. Mixed models are used to obtain estimates of efficacy from the partial data provided by each subject while adherent to assigned treatment (under the 'missing at random' assumption). The 'explanatory' estimands (target of the mixed model estimation) are defined in terms of population quantities that would have occurred had all subjects remained on assigned treatment throughout the study. The point estimate for each arm is reported under Number. (NCT00130923)
Timeframe: 6 months

Interventionordinal unit of severity (Number)
Risperidone Long Acting Injectable (LAI)4.02
Oral Risperidone Aka Risperal3.96

Change Over Time in Frequency of Heavy Drinking Days (Used to Evaluate Treatment Efficacy)

Frequency of heavy drinking days is obtained each week retrospectively as the number of heavy drinking days during the prior week (assessed by the Timeline Followback Scale). A heavy drinking day is defined as 4 or more drinks per day for a female and 5 or more drinks per day for a male. Mixed models are used to obtain estimates of efficacy from the partial data provided by each subject while adherent to assigned treatment (under the 'missing at random' assumption). The 'explanatory' estimands (target of the mixed model estimation) are defined in terms of population quantities that would have occurred had all subjects remained on assigned treatment throughout the study. The point estimate for each arm is reported under Number. (NCT00130923)
Timeframe: 6 months

Interventionheavy drinking days per week (Number)
Risperidone Long Acting Injectable (LAI)-.11
Oral Risperidone Aka Risperal.68

Number of Participants With Medication Adherence

Number of participants with medication adherence (defined as taking medication at least 75% of the days in the treatment period). (NCT00130923)
Timeframe: 6 months

InterventionParticipants (Count of Participants)
Risperidone Long Acting Injectable (LAI)43
Oral Risperidone Aka Risperdal28

Reviews

31 reviews available for homovanillic acid and Schizophrenia

ArticleYear
Pathogenesis of schizophrenia: Part II. Temporo-frontal two-step hypothesis.
    Psychiatry and clinical neurosciences, 2003, Volume: 57, Issue:1

    Topics: Amygdala; Animals; Disease Models, Animal; Dopamine; Entorhinal Cortex; Frontal Lobe; Homovanillic A

2003
[Neurotransmitters and neuropeptides in schizophrenia].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1984, Volume: 29, Issue:14

    Topics: Acetylcholine; Brain Chemistry; Endorphins; Enkephalins; Homovanillic Acid; Humans; Hydroxyindoleace

1984
[Problem of neuronal reception and the dopamine hypothesis of schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:5

    Topics: Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Apomorphine; Blood Platelets; Brain; Bro

1980
[Biological methods of predicting the effectiveness of psychopharmacologic treatment of schizophrenia (review)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:8

    Topics: Antipsychotic Agents; Apomorphine; Cyclic AMP; Drug Evaluation; Electroencephalography; Evoked Poten

1981
Cerebrospinal fluid probenecid studies: a reinterpretation.
    Biological psychiatry, 1983, Volume: 18, Issue:11

    Topics: Biological Transport; Brain; Depressive Disorder; Dopamine; Homovanillic Acid; Humans; Hydroxyindole

1983
Genetic studies of CSF monoamine metabolites.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Biogenic Amines; Blood Platelets; Dopamine beta-Hydroxylase; Female; Homovanillic Acid; Humans; Hydr

1984
[Etiology of schizophrenia: neurochemical aspects].
    Neurologia (Barcelona, Spain), 1994, Volume: 9, Issue:2

    Topics: Antipsychotic Agents; Dopamine Antagonists; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mon

1994
Biochemical findings of negative symptoms in schizophrenia and their putative relevance to pharmacologic treatment. A review.
    Neuropsychobiology, 1994, Volume: 30, Issue:4

    Topics: Antidepressive Agents; Antipsychotic Agents; Brain; Dopamine; Homovanillic Acid; Humans; Monoamine O

1994
Predictors of response to neuroleptic treatment in schizophrenia.
    The Psychiatric clinics of North America, 1993, Volume: 16, Issue:2

    Topics: Antipsychotic Agents; Brain; Electroencephalography; Homovanillic Acid; Humans; Neuropsychological T

1993
A meta-analysis of homovanillic acid concentrations in schizophrenia.
    The International journal of neuroscience, 1993, Volume: 73, Issue:1-2

    Topics: Dopamine; Female; Homovanillic Acid; Humans; Male; Schizophrenia

1993
Clozapine response and plasma catecholamines and their metabolites.
    Psychiatry research, 1993, Volume: 46, Issue:2

    Topics: Adult; Brain; Catecholamines; Clozapine; Dose-Response Relationship, Drug; Female; Homovanillic Acid

1993
Clozapine response and plasma catecholamines and their metabolites.
    Psychiatry research, 1993, Volume: 46, Issue:2

    Topics: Adult; Brain; Catecholamines; Clozapine; Dose-Response Relationship, Drug; Female; Homovanillic Acid

1993
Clozapine response and plasma catecholamines and their metabolites.
    Psychiatry research, 1993, Volume: 46, Issue:2

    Topics: Adult; Brain; Catecholamines; Clozapine; Dose-Response Relationship, Drug; Female; Homovanillic Acid

1993
Clozapine response and plasma catecholamines and their metabolites.
    Psychiatry research, 1993, Volume: 46, Issue:2

    Topics: Adult; Brain; Catecholamines; Clozapine; Dose-Response Relationship, Drug; Female; Homovanillic Acid

1993
Neurochemical brain imaging investigations of schizophrenia.
    Biological psychiatry, 1999, Sep-01, Volume: 46, Issue:5

    Topics: Aspartic Acid; Brain; Corpus Striatum; Dopamine; Glutamic Acid; Homovanillic Acid; Humans; Magnetic

1999
[Biological approaches to acute psychoses].
    L'Encephale, 1999, Volume: 25 Spec No 3

    Topics: Acute Disease; Antipsychotic Agents; Brain; Cognition Disorders; Homovanillic Acid; Humans; Magnetic

1999
[Dopamine hypothesis in schizophrenia--recent findings in limbic system abnormality].
    Nihon rinsho. Japanese journal of clinical medicine, 1978, Volume: 36, Issue:1

    Topics: Antipsychotic Agents; Dopamine; Homovanillic Acid; Humans; Limbic System; Receptors, Dopamine; Schiz

1978
[Schizophrenia and dopamine (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1978, Volume: 23, Issue:4

    Topics: Amphetamines; Animals; Antipsychotic Agents; Brain; Dopamine; Dopamine Antagonists; Extrapyramidal T

1978
Dopamine and schizophrenia.
    Advances in biochemical psychopharmacology, 1978, Volume: 19

    Topics: Amphetamines; Antipsychotic Agents; Brain; Dopamine; Glutamate Decarboxylase; Homovanillic Acid; Hum

1978
[Current biochemical conceptions of mental disorders. I. Biogenic amines in the pathogenesis of schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:8

    Topics: Animals; Biogenic Amines; Blood Platelets; Brain Chemistry; Catechol O-Methyltransferase; Disease Mo

1979
Studies of amine metabolites in affective illness and in schizophrenia: a comparative analysis.
    Research publications - Association for Research in Nervous and Mental Disease, 1975, Volume: 54

    Topics: 3,4-Dihydroxyphenylacetic Acid; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depressio

1975
Structure-function relations in schizophrenia: brain morphology and neuropsychology.
    Progress in experimental personality & psychopathology research, 1992, Volume: 15

    Topics: Brain; Cerebral Ventricles; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Psych

1992
Homovanillic acid measurement in clinical research: a review of methodology.
    Schizophrenia bulletin, 1992, Volume: 18, Issue:1

    Topics: Body Fluids; Brain Diseases; Female; Homovanillic Acid; Humans; Male; Schizophrenia

1992
Dopamine in schizophrenia: a review and reconceptualization.
    The American journal of psychiatry, 1991, Volume: 148, Issue:11

    Topics: Animals; Antipsychotic Agents; Brain; Cognition; Dopamine; Frontal Lobe; Homovanillic Acid; Humans;

1991
Dopamine in schizophrenia: a review and reconceptualization.
    The American journal of psychiatry, 1991, Volume: 148, Issue:11

    Topics: Animals; Antipsychotic Agents; Brain; Cognition; Dopamine; Frontal Lobe; Homovanillic Acid; Humans;

1991
Dopamine in schizophrenia: a review and reconceptualization.
    The American journal of psychiatry, 1991, Volume: 148, Issue:11

    Topics: Animals; Antipsychotic Agents; Brain; Cognition; Dopamine; Frontal Lobe; Homovanillic Acid; Humans;

1991
Dopamine in schizophrenia: a review and reconceptualization.
    The American journal of psychiatry, 1991, Volume: 148, Issue:11

    Topics: Animals; Antipsychotic Agents; Brain; Cognition; Dopamine; Frontal Lobe; Homovanillic Acid; Humans;

1991
Measurement of plasma homovanillic acid concentrations in schizophrenic patients.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:3

    Topics: Biomarkers; Circadian Rhythm; Diet; Homovanillic Acid; Humans; Physical Exertion; Schizophrenia

1990
Cerebrospinal fluid studies of monoamine metabolism in schizophrenia.
    The Psychiatric clinics of North America, 1986, Volume: 9, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Antipsychotic Agents; Catecholamines; Cyclic AMP; Dopamine; Dopamine

1986
A critical appraisal of CSF monoamine metabolite studies in schizophrenia.
    Annals of the New York Academy of Sciences, 1988, Volume: 537

    Topics: 3,4-Dihydroxyphenylacetic Acid; Biogenic Monoamines; Dopamine; Homovanillic Acid; Humans; Hydroxyind

1988
Dopaminergic balance and subtypes of schizophrenia.
    The British journal of psychiatry. Supplement, 1989, Issue:4

    Topics: Brain; Dopamine; Homovanillic Acid; Humans; Schizophrenia; Schizophrenic Psychology

1989
Beyond the dopamine hypothesis. The neurochemical pathology of schizophrenia.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 155

    Topics: Brain; Dopamine; Homovanillic Acid; Humans; Limbic System; Receptors, Dopamine; Schizophrenia

1989
Neuroendocrinological and biochemical effects of chronic neuroleptic treatment.
    Advances in biochemical psychopharmacology, 1985, Volume: 40

    Topics: Adult; Antipsychotic Agents; Apomorphine; beta-Endorphin; Drug Tolerance; Endocrine System Diseases;

1985
Perspectives on a time-dependent model of neuroleptic action.
    Schizophrenia bulletin, 1988, Volume: 14, Issue:2

    Topics: Antipsychotic Agents; Brain; Homovanillic Acid; Humans; Methoxyhydroxyphenylglycol; Receptors, Dopam

1988
Plasma homovanillic acid as an index of central dopaminergic activity: studies in schizophrenic patients.
    Annals of the New York Academy of Sciences, 1988, Volume: 537

    Topics: Animals; Antipsychotic Agents; Brain; Cerebral Cortex; Debrisoquin; Dopamine; Homovanillic Acid; Hum

1988
Implications of catecholamine systems of the brain in schizophrenia.
    Research publications - Association for Research in Nervous and Mental Disease, 1974, Volume: 53

    Topics: Amphetamine; Brain; Catecholamines; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Histamine H1 A

1974
Antipsychotic drug actions: a clue to the neuropathology of schizophrenia?
    Federation proceedings, 1973, Volume: 32, Issue:2

    Topics: Animals; Basal Ganglia Diseases; Brain; Butyrophenones; Cognition; Dogs; Dopamine; Haplorhini; Homov

1973

Trials

81 trials available for homovanillic acid and Schizophrenia

ArticleYear
Dopaminergic modulation of the reward system in schizophrenia: a placebo-controlled dopamine depletion fMRI study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013, Volume: 23, Issue:11

    Topics: Adult; alpha-Methyltyrosine; Anticipation, Psychological; Brain; Brain Mapping; Dopamine; Double-Bli

2013
Switching antipsychotics to aripiprazole or blonanserin and plasma monoamine metabolites levels in patients with schizophrenia.
    Human psychopharmacology, 2014, Volume: 29, Issue:2

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Chromatography, High Pressure Liquid; Female; Homovanilli

2014
Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine.
    Journal of psychiatric research, 2010, Volume: 44, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antipsychotic Agents; Benzamides; Biogenic Monoamines; Brain

2010
Effects of aripiprazole and the Taq1A polymorphism in the dopamine D2 receptor gene on the clinical response and plasma monoamine metabolites level during the acute phase of schizophrenia.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:1

    Topics: Acute Disease; Adult; Alleles; Antipsychotic Agents; Aripiprazole; Female; Genetic Carrier Screening

2012
Aripiprazole altered plasma levels of brain-derived neurotrophic factor and catecholamine metabolites in first-episode untreated Japanese schizophrenia patients.
    Human psychopharmacology, 2012, Volume: 27, Issue:1

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Brain-Derived Neurotrophic Factor; Case-Control Studies;

2012
Effect of switching to risperidone after unsuccessful treatment with aripiprazole on plasma monoamine metabolites level in the treatment of acute schizophrenia.
    Human psychopharmacology, 2012, Volume: 27, Issue:5

    Topics: Acute Disease; Adult; Antipsychotic Agents; Aripiprazole; Chromatography, High Pressure Liquid; Fema

2012
Modulating sensory gating in healthy volunteers: the effects of ketamine and haloperidol.
    Biological psychiatry, 2002, Nov-01, Volume: 52, Issue:9

    Topics: Adult; Antipsychotic Agents; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electroencepha

2002
Plasma levels of homovanillic acid and the response to risperidone in first episode untreated acute schizophrenia.
    International clinical psychopharmacology, 2003, Volume: 18, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Mal

2003
Impact of risperidone medication on quality of life and gonadal axis hormones in schizophrenia male patients with acute exacerbation.
    The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:3

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Gonadal Steroid Hormones; Homovanillic Acid; Hu

2003
Atypical antipsychotics and the relevance of glutamate and serotonin.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2004, Volume: 14, Issue:3

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Case-Control Studies; Chromatography, High Pressu

2004
Prediction of changes in memory performance by plasma homovanillic acid levels in clozapine-treated patients with schizophrenia.
    Psychopharmacology, 2004, Volume: 177, Issue:1-2

    Topics: Adult; Clozapine; Homovanillic Acid; Humans; Male; Memory; Predictive Value of Tests; Psychomotor Pe

2004
Abnormal response to metabolic stress in schizophrenia: marker of vulnerability or acquired sensitization?
    Psychological medicine, 2004, Volume: 34, Issue:6

    Topics: Adolescent; Adult; Antimetabolites; Blood Glucose; Case-Control Studies; Deoxyglucose; Female; Genet

2004
An open study of risperidone liquid in the acute phase of schizophrenia.
    Human psychopharmacology, 2005, Volume: 20, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Chromatography, High Pressure Liquid;

2005
Effects of olanzapine on plasma levels of catecholamine metabolites, cytokines, and brain-derived neurotrophic factor in schizophrenic patients.
    International clinical psychopharmacology, 2007, Volume: 22, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain-Derived Neurotrophic Factor; Catecholamines; Cyt

2007
Serotonergic response to stress: a protective factor against abnormal dopaminergic reactivity in schizophrenia?
    European psychiatry : the journal of the Association of European Psychiatrists, 2007, Volume: 22, Issue:6

    Topics: Adult; Antimetabolites; Arousal; Cross-Over Studies; Deoxyglucose; Dopamine; Double-Blind Method; Fe

2007
The effect of propranolol on CSF amine metabolites in psychiatric patients.
    British journal of clinical pharmacology, 1983, Volume: 15, Issue:3

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Female; Glycols; Homovanillic Acid; Humans; Hydrox

1983
Relationships between drug concentrations in serum and CSF, clinical effects and monoaminergic variables in schizophrenic patients treated with sulpiride or chlorpromazine.
    Acta psychiatrica Scandinavica. Supplementum, 1984, Volume: 311

    Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Female; Homovanill

1984
Clinical, biochemical, and hormonal aspects of treatment with Des-tyr1-gamma-endorphin in schizophrenia.
    Psychiatry research, 1984, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Endorphins; Female; Growth Hormone

1984
Apomorphine and schizophrenia. Treatment, CSF, and neuroendocrine responses.
    Archives of general psychiatry, 1984, Volume: 41, Issue:5

    Topics: Adult; Apomorphine; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Growth Hormone; Homovanillic

1984
Lithium prevents adaptation of brain dopamine systems to haloperidol in schizophrenic patients.
    Psychiatry research, 1983, Volume: 10, Issue:2

    Topics: Adult; Brain; Drug Therapy, Combination; Drug Tolerance; Female; Haloperidol; Homovanillic Acid; Hum

1983
Apomorphine and schizophrenia.
    Psychopharmacology bulletin, 1984,Winter, Volume: 20, Issue:1

    Topics: Adult; Apomorphine; Dyskinesia, Drug-Induced; Homovanillic Acid; Hormones; Humans; Male; Middle Aged

1984
Sodium valproate in schizophrenia: some biochemical correlates.
    The British journal of psychiatry : the journal of mental science, 1980, Volume: 137

    Topics: Adult; Clinical Trials as Topic; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Male; Methoxyhy

1980
Low-dose apomorphine reduces serum homovanillic acid concentrations in schizophrenic patients.
    Life sciences, 1982, Mar-01, Volume: 30, Issue:9

    Topics: Adult; Apomorphine; Female; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Male; P

1982
Predictors of clozapine response in schizophrenia.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl B

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Double-Blind Method; Female; Fluphen

1994
The dopamine-serotonin relationship in clozapine response.
    Psychopharmacology, 1993, Volume: 112, Issue:1 Suppl

    Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Dopamine; Drug Resistance; Dyskinesia, Drug-Indu

1993
Effects of raclopride treatment on plasma and CSF HVA: relationships with clinical improvement in male schizophrenics.
    Psychopharmacology, 1994, Volume: 116, Issue:3

    Topics: Adult; Dopamine Antagonists; Double-Blind Method; Homovanillic Acid; Humans; Hydroxyindoleacetic Aci

1994
Plasma levels of benperidol, prolactin, and homovanillic acid after intravenous versus two different kinds of oral application of the neuroleptic in schizophrenic patients.
    Experimental and clinical endocrinology, 1994, Volume: 102, Issue:4

    Topics: Administration, Oral; Adult; Benperidol; Cross-Over Studies; Female; Homovanillic Acid; Humans; Inje

1994
Methylphenidate response, psychopathology and tardive dyskinesia as predictors of relapse in schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1994, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Blinking; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Follow-Up Studie

1994
Acute effects of neuroleptics on unmedicated schizophrenic patients and controls.
    Biological psychiatry, 1993, Aug-01, Volume: 34, Issue:3

    Topics: Adult; Antipsychotic Agents; Brain; Debrisoquin; Dopamine; Haloperidol; Homovanillic Acid; Humans; M

1993
Beneficial effects of nalmefene augmentation in neuroleptic-stabilized schizophrenic patients.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Hom

1993
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Blood Pressure; Cognition; Dissociative Disorders; Dose-Response Relationship, Drug; Double-B

1994
Memory and plasma HVA changes in schizophrenia: are they episode markers?
    Biological psychiatry, 1994, Feb-01, Volume: 35, Issue:3

    Topics: Adult; Biomarkers; Cognition Disorders; Double-Blind Method; Haloperidol; Homovanillic Acid; Humans;

1994
Plasma homovanillic acid and treatment response in a large group of schizophrenic patients.
    Schizophrenia research, 1993, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Flupenthi

1993
Plasma homovanillic acid in neuroleptic responsive and nonresponsive schizophrenics.
    Biological psychiatry, 1993, Oct-15, Volume: 34, Issue:8

    Topics: Adult; Analysis of Variance; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloper

1993
Effects of metabolic perturbation on plasma homovanillic acid in schizophrenia. Relationship to prefrontal cortex volume.
    Archives of general psychiatry, 1993, Volume: 50, Issue:7

    Topics: Adult; Blood Pressure; Deoxyglucose; Dopamine; Double-Blind Method; Female; Frontal Lobe; Heart Rate

1993
Differential effects of haloperidol on negative symptoms in drug-naive schizophrenic patients: effects on plasma homovanillic acid.
    Schizophrenia research, 1993, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Affect; Arousal; Attention; Brain; Dose-Response Relationship, Drug; Double-Blind

1993
Studies of catecholamine metabolism in schizophrenia/psychosis--II.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Catecholamines; Circadian Rhythm; Haloperidol; Homovanillic Acid;

1993
Studies of catecholamine metabolism in schizophrenia/psychosis--I.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Blood Platelets; Catecholamines; Debrisoquin; Double-Blind Method

1993
Plasma homovanillic acid levels and therapeutic outcome in schizophrenics: comparisons of neuroleptic-naive first-episode patients and patients with disease exacerbation due to neuroleptic discontinuance.
    Biological psychiatry, 1995, Nov-15, Volume: 38, Issue:10

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Brief Psychiatric Rating Scale; Female; Fluphenaz

1995
Pharmacoclinical correlations in schizophrenic patients treated with haloperidol decanoate: clinical evaluations, concentrations of plasma and red blood cell haloperidol and its reduced metabolite, and plasma homovanillic acid.
    Progress in neuro-psychopharmacology & biological psychiatry, 1995, Volume: 19, Issue:7

    Topics: Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Erythrocytes; Female; Haloperidol; Homo

1995
Catatonia: short-term response to lorazepam and dopaminergic metabolism.
    Psychopharmacology, 1995, Volume: 122, Issue:2

    Topics: Acute Disease; Adult; Anti-Anxiety Agents; Anxiety; Catatonia; Depressive Disorder; Dopamine; Dyskin

1995
Predicting haloperidol treatment response in chronic schizophrenia.
    Psychiatry research, 1996, Aug-30, Volume: 64, Issue:1

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Haloperidol; Homovanillic Acid; Humans; Male; Methoxyh

1996
A study of the potential confounding effects of diet, caffeine, nicotine and lorazepam on the stability of plasma and urinary homovanillic acid levels in patients with schizophrenia.
    Biological psychiatry, 1996, Dec-15, Volume: 40, Issue:12

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Diet; Drug Interactions; GABA Modulators; Homova

1996
Effects of clozapine on plasma catecholamines and relation to treatment response in schizophrenia: a within-subject comparison with haloperidol.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 17, Issue:5

    Topics: Aged; Analysis of Variance; Antipsychotic Agents; Clozapine; Haloperidol; Homovanillic Acid; Humans;

1997
Differential effect of haloperidol and clozapine on plasma homovanillic acid in elderly schizophrenic patients with or without tardive dyskinesia.
    Biological psychiatry, 1998, Jan-01, Volume: 43, Issue:1

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Clozapine; Dyskinesia, Drug-Induced; Female; Haloperi

1998
Plasma 3-methoxy-4-hydroxyphenylglycol and homovanillic acid measurements in deficit and nondeficit forms of schizophrenia.
    Biological psychiatry, 1998, Jan-01, Volume: 43, Issue:1

    Topics: Aged; Female; Homovanillic Acid; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephri

1998
The partial NMDA agonist D-cycloserine stimulates LH secretion in healthy volunteers.
    Psychopharmacology, 1998, Volume: 138, Issue:2

    Topics: Adult; Affect; Antipsychotic Agents; Behavior; Blood Pressure; Body Temperature; Brief Psychiatric R

1998
Pretreatment plasma homovanillic acid in schizophrenia and schizoaffective disorder: the influence of demographic variables and the inpatient drug-free period.
    Biological psychiatry, 1998, Sep-15, Volume: 44, Issue:6

    Topics: Adult; Age of Onset; Brief Psychiatric Rating Scale; Female; Homovanillic Acid; Humans; Male; Psycho

1998
Auditory P50 in schizophrenics on clozapine: improved gating parallels clinical improvement and changes in plasma 3-methoxy-4-hydroxyphenylglycol.
    Neuropsychobiology, 1999, Volume: 39, Issue:1

    Topics: Adult; Antipsychotic Agents; Clozapine; Electroencephalography; Evoked Potentials, Auditory; Female;

1999
Differential effects of mental stress on plasma homovanillic acid in schizophrenia and normal controls.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Homovanillic Acid; Humans; Male; Reference Values; Schizophrenia; Schizophrenic P

1999
The effect of olanzapine treatment on monoamine metabolite concentrations in the cerebrospinal fluid of schizophrenic patients.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; M

2001
Monoamine metabolite levels in cerebrospinal fluid of psychotic women treated with melperone or thiothixene.
    Archiv fur Psychiatrie und Nervenkrankheiten, 1977, Oct-11, Volume: 224, Issue:2

    Topics: Antipsychotic Agents; Butyrophenones; Clinical Trials as Topic; Double-Blind Method; Female; Glycols

1977
Tardive dyskinesia: a clinical test of the supersensitivity hypothesis.
    Psychopharmacology, 1979, Mar-22, Volume: 61, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Cyclic AMP; Depression; Dyskinesia, Drug-Induced; Female; Hom

1979
Potentiation by metyrosine of thioridazine effects in chronic schizophrenics. A long-term trial using double-blind crossover technique.
    Archives of general psychiatry, 1976, Volume: 33, Issue:4

    Topics: Aged; Chronic Disease; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female;

1976
Effect of chlorpromazine treatment on monoamine metabolite levels in cerebrospinal fluid of psychotic patients.
    Acta psychiatrica Scandinavica, 1977, Volume: 56, Issue:2

    Topics: Adult; Aged; Chlorpromazine; Ethylene Glycols; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti

1977
Extrapyramidal reactions and amine metabolites in cerebrospinal fluid during haloperidol and clozapine treatment of schizophrenic patients.
    Psychopharmacologia, 1975, Volume: 40, Issue:4

    Topics: Adult; Aged; Basal Ganglia Diseases; Clinical Trials as Topic; Clozapine; Dibenzazepines; Haloperido

1975
Placebo-controlled, double-blind study of the effects of proglumide in the treatment of schizophrenia.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:5

    Topics: Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administrat

1992
Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine.
    Archives of general psychiatry, 1992, Volume: 49, Issue:5

    Topics: Adult; Antipsychotic Agents; Clozapine; Dopamine; Double-Blind Method; Female; Fluphenazine; Homovan

1992
Neuroleptic treatment, symptoms of schizophrenia, and plasma homovanillic acid concentrations revisited.
    Archives of general psychiatry, 1992, Volume: 49, Issue:12

    Topics: Acute Disease; Haloperidol; Homovanillic Acid; Humans; Placebos; Psychiatric Status Rating Scales; S

1992
Plasma prolactin and homovanillic acid as markers for psychopathology and abnormal movements after neuroleptic dose decrease.
    Psychopharmacology bulletin, 1992, Volume: 28, Issue:1

    Topics: Adult; Aged; Biomarkers; Dose-Response Relationship, Drug; Double-Blind Method; Dyskinesia, Drug-Ind

1992
Behavioral and biochemical effects of methylphenidate in schizophrenic and nonschizophrenic patients.
    Biological psychiatry, 1991, Sep-01, Volume: 30, Issue:5

    Topics: Adult; Brain; Depressive Disorder; Double-Blind Method; Female; Growth Hormone; Homovanillic Acid; H

1991
Plasma homovanillic acid, serum anti-D1 and anti-D2 receptor activity, and psychopathology in chronic schizophrenia.
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1991, Volume: 11, Issue:1

    Topics: Antipsychotic Agents; Benzazepines; Chronic Disease; Haloperidol; Homovanillic Acid; Humans; Male; M

1991
Double blind comparative study of remoxipride and haloperidol in acute schizophrenic patients.
    Psychopharmacology, 1990, Volume: 102, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Benzamides; Delayed-Action Preparations; Dou

1990
Pharmacological effects of methylphenidate on plasma homovanillic acid and growth hormone.
    Psychiatry research, 1990, Volume: 32, Issue:1

    Topics: Adult; Affective Disorders, Psychotic; Blood Pressure; Brain; Double-Blind Method; Female; Growth Ho

1990
Cholecystokinin, dopamine and schizophrenia.
    Psychopharmacology bulletin, 1990, Volume: 26, Issue:3

    Topics: Adult; Cholecystokinin; Dopamine; Female; Haloperidol; Homovanillic Acid; Humans; Male; Neurons; Sch

1990
Circadian variation of plasma homovanillic acid levels is attenuated by fluphenazine in patients with schizophrenia.
    Archives of general psychiatry, 1990, Volume: 47, Issue:6

    Topics: Adult; Circadian Rhythm; Depression, Chemical; Dopamine; Female; Fluphenazine; Homovanillic Acid; Hu

1990
Hemodialysis in the treatment of a group of schizophrenic patients.
    Acta psychiatrica Scandinavica. Supplementum, 1985, Volume: 321

    Topics: Adult; Cholesterol, HDL; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; H

1985
Clonidine treatment of schizophrenia: can we predict treatment response?
    Psychiatry research, 1989, Volume: 27, Issue:3

    Topics: Adult; Clinical Trials as Topic; Clonidine; Growth Hormone; Homovanillic Acid; Humans; Hydroxyindole

1989
Melperone in the treatment of schizophrenia.
    Acta psychiatrica Scandinavica. Supplementum, 1989, Volume: 352

    Topics: Antipsychotic Agents; Butyrophenones; Diazepam; Double-Blind Method; Drug Therapy, Combination; Homo

1989
Monoamine metabolites and amino acids in serum from schizophrenic patients before and during sulpiride treatment.
    Psychopharmacology, 1989, Volume: 99, Issue:3

    Topics: Adolescent; Adult; Amino Acids; Biogenic Monoamines; Female; Glutamates; Glutamine; Homovanillic Aci

1989
A.E. Bennett award paper. Experimental approaches to human stress research: assessment of neurobiological mechanisms of stress in volunteers and psychiatric patients.
    Biological psychiatry, 1989, Volume: 26, Issue:5

    Topics: Adrenocorticotropic Hormone; Adult; Arousal; beta-Endorphin; Blood Glucose; Clinical Trials as Topic

1989
Fluphenazine treatment reduces CSF somatostatin in patients with schizophrenia: correlations with CSF HVA.
    Biological psychiatry, 1989, Feb-15, Volume: 25, Issue:4

    Topics: Adult; Brain; Clinical Trials as Topic; Female; Fluphenazine; Homovanillic Acid; Humans; Male; Schiz

1989
Clozapine in China: a review and preview of US/PRC collaboration.
    Psychopharmacology, 1989, Volume: 99 Suppl

    Topics: Adult; China; Chlorpromazine; Clozapine; Dibenzazepines; Double-Blind Method; Female; Homovanillic A

1989
Pharmacodynamics and pharmacokinetics of haloperidol and reduced haloperidol in schizophrenic patients.
    Biological psychiatry, 1989, Volume: 26, Issue:3

    Topics: Adult; Biological Availability; Brain; Chronic Disease; Haloperidol; Homovanillic Acid; Humans; Male

1989
Metabolic stress effects in normal volunteers and schizophrenic patients.
    Psychopharmacology bulletin, 1988, Volume: 24, Issue:3

    Topics: Adrenocorticotropic Hormone; Deoxyglucose; Endorphins; Female; Homovanillic Acid; Humans; Hydrocorti

1988
Plasma amine metabolites before and after withdrawal from neuroleptic treatment in chronic schizophrenic inpatients.
    Psychiatry research, 1988, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Antipsychotic Agents; Brain; Catecholamines; Clinical Trials as Topic; Double-Bli

1988
Urine and plasma levels of dopamine metabolites in response to apomorphine and neuroleptics in schizophrenics.
    Biological psychiatry, 1988, Volume: 24, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Apomorphine; Chronic Disease; Clinical Trials as Topic; Diben

1988
Clinical and biochemical effects of verapamil administration to schizophrenic patients.
    Archives of general psychiatry, 1987, Volume: 44, Issue:2

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Emotions; Female; Homovanillic Acid; Hostility

1987
Longitudinal measurement of plasma homovanillic acid levels in schizophrenic patients. Correlation with psychosis and response to neuroleptic treatment.
    Archives of general psychiatry, 1986, Volume: 43, Issue:7

    Topics: Adult; Dopamine; Female; Fluphenazine; Homovanillic Acid; Humans; Male; Middle Aged; Psychiatric Sta

1986
Clozapine and haloperidol in a single-blind cross-over trial: therapeutic and biochemical aspects in the treatment of schizophrenia.
    Acta psychiatrica Scandinavica, 1974, Volume: 50, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dibenzazepi

1974
The effect of chlorpromazine on homovanillic acid levels in cerebrospinal fluid of schizophrenic patients.
    Psychopharmacologia, 1974, Mar-09, Volume: 35, Issue:4

    Topics: Adult; Chlorpromazine; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Humans; Male; Ma

1974

Other Studies

298 other studies available for homovanillic acid and Schizophrenia

ArticleYear
[Variations in fecal microbiota of first episode schizophrenia associated with clinical assessment and serum metabolomics].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2022, Oct-18, Volume: 54, Issue:5

    Topics: Antipsychotic Agents; Feces; Homovanillic Acid; Humans; Metabolomics; Methionine; Microbiota; Prolin

2022
Plasma levels of 3-methoxy-4-hydroxyphenylglycol levels, number of hospitalization and cognitive function predicts the cognitive effect of atypical antipsychotic monotherapy in patients with acute schizophrenia.
    International clinical psychopharmacology, 2020, Volume: 35, Issue:2

    Topics: Adult; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Cognition; Female; Homovanillic Acid

2020
Plasma monoamines change under dopamine supersensitivity psychosis in patients with schizophrenia: A comparison with first-episode psychosis.
    Journal of psychopharmacology (Oxford, England), 2020, Volume: 34, Issue:5

    Topics: Adult; Aged; Antipsychotic Agents; Dopamine; Female; Homovanillic Acid; Humans; Male; Methoxyhydroxy

2020
Plasma levels of dopamine metabolite correlate with mismatch negativity in patients with schizophrenia.
    Psychiatry and clinical neurosciences, 2020, Volume: 74, Issue:5

    Topics: Adult; Dopamine; Electroencephalography; Evoked Potentials; Evoked Potentials, Auditory; Female; Hom

2020
Preventive role of regular low-intensity exercise during adolescence in schizophrenia model mice with abnormal behaviors.
    Biochemical and biophysical research communications, 2021, 01-01, Volume: 534

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Behavior, Animal; Disease Models, Animal; Dopa

2021
Reduction of dopamine and glycogen synthase kinase-3 signaling in rat striatum after continuous administration of haloperidol.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 202

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Corpus Striatum; Dopamine; Glycogen S

2021
Dynamic changes in near-infrared spectroscopy (NIRS) findings in first-episode schizophrenia: a case report.
    Fukushima journal of medical science, 2017, Apr-28, Volume: 63, Issue:1

    Topics: Acute Disease; Adolescent; Antipsychotic Agents; Biomarkers; Blood Volume; Cerebrovascular Circulati

2017
No major influence of regular tobacco smoking on cerebrospinal fluid monoamine metabolite concentrations in patients with psychotic disorder and healthy individuals.
    Psychiatry research, 2018, Volume: 263

    Topics: Adolescent; Adult; Biogenic Monoamines; Biomarkers; Female; Homovanillic Acid; Humans; Hydroxyindole

2018
Influence of -141C Ins/Del Polymorphism in DRD2 Gene on Clinical Symptoms and Plasma Homovanillic Acid Levels in the Treatment of Schizophrenia With Aripiprazole.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:3

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Female; Homovanillic Acid; Humans; INDEL Mutation; Male;

2015
Associations between five-factor model of the Positive and Negative Syndrome Scale and plasma levels of monoamine metabolite in patients with schizophrenia.
    Psychiatry research, 2015, Dec-15, Volume: 230, Issue:2

    Topics: Adult; Antipsychotic Agents; Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Humans

2015
Relationships between serum brain-derived neurotrophic factor, plasma catecholamine metabolites, cytokines, cognitive function and clinical symptoms in Japanese patients with chronic schizophrenia treated with atypical antipsychotic monotherapy.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2017, Volume: 18, Issue:5

    Topics: Adult; Antipsychotic Agents; Biomarkers; Brain-Derived Neurotrophic Factor; Case-Control Studies; Ch

2017
Genetic and Functional Study of L-Type Amino Acid Transporter 1 in Schizophrenia.
    Neuropsychobiology, 2016, Volume: 74, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cells, Cultured; Female; Fibroblasts; Genetic

2016
Blood Biomarkers Predict the Cognitive Effects of Aripiprazole in Patients with Acute Schizophrenia.
    International journal of molecular sciences, 2017, Mar-06, Volume: 18, Issue:3

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Biomarkers; Brain-Derived Neurotrophic Factor; Cognition;

2017
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia.
    The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Press

2009
Plasma homovanillic acid differences in clinical subgroups of first episode schizophrenic patients.
    Psychiatry research, 2009, Jul-30, Volume: 168, Issue:2

    Topics: Adult; Antipsychotic Agents; Dopamine; Female; Follow-Up Studies; Homovanillic Acid; Humans; Male; P

2009
GABA and homovanillic acid in the plasma of Schizophrenic and bipolar I patients.
    Neurochemical research, 2010, Volume: 35, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Bipolar Disorder; Dopamine; Female; gamma-Aminobutyric Acid; Homovani

2010
Associations between plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) and negative symptoms or cognitive impairments in early-stage schizophrenia.
    Human psychopharmacology, 2009, Volume: 24, Issue:8

    Topics: Adolescent; Adult; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Cognition Disorders; Fem

2009
Different patterns of longitudinal changes in plasma levels of catecholamine metabolites and brain-derived neurotrophic factor after administration of atypical antipsychotics in first episode untreated schizophrenic patients.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2010, Volume: 11, Issue:2 Pt 2

    Topics: Adolescent; Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brain-Derived Neurotrophic F

2010
Comparison of brain N-acetylaspartate levels and serum brain-derived neurotrophic factor (BDNF) levels between patients with first-episode schizophrenia psychosis and healthy controls.
    European psychiatry : the journal of the Association of European Psychiatrists, 2011, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Brain Chemistry; Brain-Derived Neurotrophic Factor;

2011
Early death and CSF monoamine metabolites in schizophrenia spectrum psychosis.
    Nordic journal of psychiatry, 2011, Volume: 65, Issue:2

    Topics: Adult; Age Factors; Cause of Death; Cerebrospinal Fluid; Female; Follow-Up Studies; Homovanillic Aci

2011
Quetiapine and norquetiapine in plasma and cerebrospinal fluid of schizophrenic patients treated with quetiapine: correlations to clinical outcome and HVA, 5-HIAA, and MHPG in CSF.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Biomarkers; Dibenzothiazepines; Female; Homovanillic Acid; Humans; Hydroxyindolea

2010
Variability of plasma homovanillic acid over 13 months in patients with schizophrenia; relationship with the clinical response and the Wisconsin card sort test.
    Neurochemical research, 2011, Volume: 36, Issue:8

    Topics: Adult; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Male; Neuropsychological Tests; Psyc

2011
α7 neuronal nicotinic receptor agonist (TC-7020) reverses increased striatal dopamine release during acoustic PPI testing in a transgenic mouse model of schizophrenia.
    Schizophrenia research, 2012, Volume: 136, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Animals; Chromatography, High Pressure Liquid;

2012
Long-term pharmacoclinical follow-up in schizophrenic patients treated with risperidone. Plasma and red blood cell concentrations of risperidone and its 9-hydroxymetabolite and their relationship to whole blood serotonin and tryptophan, plasma homovanilli
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Biomarkers; Female; Follow-Up Studies; Homovanillic Acid; Humans;

2002
Relations of clinical features, subgroups and medication to serum monoamines in schizophrenia.
    Human psychopharmacology, 2002, Volume: 17, Issue:1

    Topics: Adult; Antipsychotic Agents; Biogenic Monoamines; Dopamine; Female; Homovanillic Acid; Humans; Hydro

2002
Effects of acute metabolic stress on the peripheral vasopressinergic system in schizophrenia.
    Journal of psychopharmacology (Oxford, England), 2003, Volume: 17, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Behavior; Female; Homovanillic Acid; Humans; Hydrocortisone; Hyd

2003
Prediction of response to risperidone treatment with respect to plasma concencentrations of risperidone, catecholamine metabolites, and polymorphism of cytochrome P450 2D6.
    International clinical psychopharmacology, 2005, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Caffeine; Catecholamines; Cen

2005
Monoaminergic dysregulation in glutathione-deficient mice: possible relevance to schizophrenia?
    Neuroscience, 2005, Volume: 132, Issue:4

    Topics: Amphetamine; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Glutathione; Hallucinog

2005
Diurnal variation in plasma homovanillic acid in patients with schizophrenia and healthy controls.
    Schizophrenia research, 2006, Jan-31, Volume: 81, Issue:2-3

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Circadian Rhythm; Female; Homovanillic Acid; Huma

2006
Fibroblast growth factor receptor signaling affects development and function of dopamine neurons - inhibition results in a schizophrenia-like syndrome in transgenic mice.
    Journal of neurochemistry, 2006, Volume: 97, Issue:5

    Topics: Animals; Cell Differentiation; Cell Enlargement; Disease Models, Animal; Dopamine; Dopamine Plasma M

2006
Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia.
    Schizophrenia research, 2006, Volume: 86, Issue:1-3

    Topics: Adolescent; Adult; Deoxyglucose; Female; Homovanillic Acid; Humans; Image Processing, Computer-Assis

2006
Inter- and intra-individual variability in the levels of plasma homovanillic acid in schizophrenic patients.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Apr-13, Volume: 31, Issue:3

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Individuality;

2007
Valproic acid improves psychotic agitation without influencing plasma risperidone levels in schizophrenic patients.
    Pharmacopsychiatry, 2007, Volume: 40, Issue:1

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Drug Interactions; Female; Homovanillic Acid; Humans;

2007
Plasma homovanillic acid levels in schizophrenic patients: correlation with negative symptoms.
    Psychiatry research, 2007, May-30, Volume: 151, Issue:1-2

    Topics: Adolescent; Adult; Antipsychotic Agents; Depression; Dopamine; Female; Hallucinations; Haloperidol;

2007
Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizophrenia, their unaffected siblings and controls.
    Schizophrenia research, 2008, Volume: 100, Issue:1-3

    Topics: Adrenocorticotropic Hormone; Adult; Control Groups; Cross-Over Studies; Deoxyglucose; Dopamine; Doub

2008
[The probenecid test and its application to research in schizophrenia].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1984, Volume: 17, Issue:4

    Topics: Biogenic Amines; Brain; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylgly

1984
[Changes in the CSF levels of monoamine metabolites in 102 chronic schizophrenic patients following probenecid before and after neuroleptic medication].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1984, Volume: 17, Issue:5

    Topics: Adult; Antipsychotic Agents; Biogenic Amines; Chronic Disease; Female; Homovanillic Acid; Humans; Hy

1984
The Genain Quadruplets 25 years later: a diagnostic and biochemical followup.
    Psychiatry research, 1984, Volume: 13, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Cyclic AMP; Dopamine beta-Hydroxylase; Environment; Female; Follow-U

1984
[State of the adrenergic and cholinergic systems of schizophrenic patients during the process of psychopharmacotherapy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:5

    Topics: Acetylcholine; Acetylcholinesterase; Adult; Antipsychotic Agents; Catecholamines; Dihydroxyphenylala

1980
Cerebrospinal fluid homovanillic acid patterns during neuroleptic treatment.
    Psychiatry research, 1981, Volume: 4, Issue:3

    Topics: Adult; Antipsychotic Agents; Chlorpromazine; Female; Haloperidol; Homovanillic Acid; Humans; Male; P

1981
"Tolerance" to neuroleptic-induced CSF HVA rise in schizophrenic patients in relation to clinical response.
    Psychiatry research, 1982, Volume: 7, Issue:1

    Topics: Antipsychotic Agents; Drug Tolerance; Homovanillic Acid; Humans; Phenylacetates; Schizophrenia

1982
The dopamine hypothesis: an overview of studies with schizophrenic patients.
    Schizophrenia bulletin, 1982, Volume: 8, Issue:3

    Topics: Adenylyl Cyclases; Brain; Catechol O-Methyltransferase; Dextroamphetamine; Dopa Decarboxylase; Dopam

1982
Effect of chronic amphetamine administration on dopaminergic systems in the vervet brain: relationship to findings in the brains of schizophrenics.
    Biochemical Society transactions, 1983, Volume: 11, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Brain; Chlorocebus aethiops; Dopa Decarboxyla

1983
Neurochemical studies on tardive dyskinesia. I. Urinary homovanillic acid and plasma prolactin.
    Biological psychiatry, 1983, Volume: 18, Issue:3

    Topics: Aged; Antipsychotic Agents; Dopamine; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Male; Mid

1983
Dopamine-beta-hydroxylase activity and homovanillic acid in spinal fluid of schizophrenics with brain atrophy.
    Science (New York, N.Y.), 1983, May-27, Volume: 220, Issue:4600

    Topics: Adolescent; Adult; Aged; Animals; Antipsychotic Agents; Atrophy; Brain; Dopamine; Dopamine beta-Hydr

1983
Urinary acid metabolites of biogenic amines in schizophrenic patients.
    Schizophrenia bulletin, 1980, Volume: 6, Issue:2

    Topics: Biogenic Amines; Blood Platelets; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Indoleacetic

1980
CSF monoamine metabolites in child and adult psychiatric patients. A developmental perspective.
    Archives of general psychiatry, 1980, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Autistic Disorder; Bipolar Disorder; Child; Child, Preschool;

1980
Aberrant monoamine metabolite levels in CSF and family history of schizophrenia. Their relationships in schizophrenic patients.
    Archives of general psychiatry, 1980, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Metho

1980
Concentrations of monoamine metabolites and chlorpromazine in cerebrospinal fluid for prediction of therapeutic response in psychotic patients treated with neuroleptic drugs.
    Progress in biochemical pharmacology, 1980, Volume: 16

    Topics: Antipsychotic Agents; Chlorpromazine; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid;

1980
Noradrenergic overactivity in chronic schizophrenia: evidence based on cerebrospinal fluid noradrenaline and cyclic nucleotide concentrations.
    The British journal of psychiatry : the journal of mental science, 1980, Volume: 137

    Topics: Adult; Chronic Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Ag

1980
Relationship between estimated premorbid adjustment and CSF homovanillic acid and 5-hydroxyindoleacetic acid levels.
    The American journal of psychiatry, 1981, Volume: 138, Issue:4

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Female; Homovanillic Acid; Humans; Hydroxyi

1981
[Catecholamine and indoleamine metabolism in groups of patients with paranoid and simple forms of schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:5

    Topics: Adult; Biogenic Amines; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Mal

1981
[Changes in the levels of adrenergic and serotoninergic indices in patients with depressive states].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:4

    Topics: Adolescent; Adult; Biogenic Amines; Depression; Dihydroxyphenylalanine; Dopamine; Epinephrine; Homov

1981
Reduced lumbar CSF somatostatin levels in Alzheimer's disease.
    Life sciences, 1982, Nov-08, Volume: 31, Issue:19

    Topics: Aged; Alcohol Amnestic Disorder; Alzheimer Disease; Dementia; Female; Homovanillic Acid; Humans; Hyd

1982
Relationship between cerebrospinal fluid amine metabolites, neuroendocrine findings and personality dimensions (Marke-Nyman scale factors) in psychiatric patients.
    Acta psychiatrica Scandinavica, 1983, Volume: 67, Issue:4

    Topics: Alcoholism; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans;

1983
Amine metabolites and neuroendocrine responses related to depression and suicide.
    Journal of affective disorders, 1983, Volume: 5, Issue:3

    Topics: Alcoholism; Depression; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; Hydro

1983
The effect of dexamethasone on cerebrospinal fluid monoamine metabolites and cortisol in psychiatric patients.
    Pharmacopsychiatria, 1983, Volume: 16, Issue:3

    Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Homovanillic

1983
Gamma-hydroxybutyrate in the treatment of schizophrenia.
    Psychiatry research, 1983, Volume: 9, Issue:1

    Topics: Adult; Double-Blind Method; Homovanillic Acid; Humans; Hydroxybutyrates; Hydroxyindoleacetic Acid; M

1983
Concentrations of 5-hydroxyindoleacetic acid and homovanillic acid in the cerebrospinal fluid of chronic therapy-resistant schizophrenics before and after hemodialysis therapy.
    Artificial organs, 1983, Volume: 7, Issue:3

    Topics: Adult; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Homovanillic Acid; Humans;

1983
Smooth pursuit eye movements, clinical symptoms, CSF metabolites, and skin conductance habituation in schizophrenic patients.
    Biological psychiatry, 1983, Volume: 18, Issue:9

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Eye Movements; Female; Galvanic Skin Response; Habitua

1983
Cerebrospinal fluid biochemical examinations: do they reflect clinical or biological differences?
    Biological psychiatry, 1983, Volume: 18, Issue:9

    Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Calcium; Depressive Disorder; Dexamethasone; Female; Homo

1983
Cerebroventricular size and cerebrospinal fluid monoamine metabolites in schizophrenic patients and healthy volunteers.
    Psychiatry research, 1983, Volume: 9, Issue:4

    Topics: Adult; Age Factors; Cerebral Ventriculography; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti

1983
Reliability of norepinephrine and major monoamine metabolite measurements in CSF of schizophrenic patients.
    Archives of general psychiatry, 1983, Volume: 40, Issue:12

    Topics: Adult; Chronic Disease; Female; Glycols; Homovanillic Acid; Hospitalization; Humans; Hydroxyindoleac

1983
Measurement of 3-methoxy-4-hydroxyphenylacetic acid (HVA) in plasma by high-performance liquid chromatography with electrochemical detector (HPLC-EC).
    Analytical biochemistry, 1983, Volume: 135, Issue:2

    Topics: Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Electrochemistry; Female; Homov

1983
Time course for effects of sulpiride and chlorpromazine on monoamine metabolite and prolactin levels in cerebrospinal fluid from schizophrenic patients.
    Acta psychiatrica Scandinavica. Supplementum, 1984, Volume: 311

    Topics: Adolescent; Adult; Cerebrospinal Fluid Proteins; Chlorpromazine; Dopamine Antagonists; Female; Homov

1984
Elevated cerebrospinal fluid noradrenaline in tardive dyskinesia.
    The British journal of psychiatry : the journal of mental science, 1984, Volume: 144

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Antipsychotic Agents; Dyskinesia, Drug-Induced; Homovan

1984
Effect of propranolol on monoamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:1

    Topics: Adult; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Evaluation; Female; Homovanil

1984
Bilateral skin conductance activity, clinical symptoms and CSF monoamine metabolite levels in unmedicated schizophrenics, differing in rate of habituation.
    Biological psychology, 1984, Volume: 18, Issue:3

    Topics: Adult; Biogenic Amines; Female; Galvanic Skin Response; Habituation, Psychophysiologic; Homovanillic

1984
Seasonal variations of human lumbar CSF neurotransmitter metabolite concentrations.
    Psychiatry research, 1984, Volume: 12, Issue:1

    Topics: Adult; Alzheimer Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxy

1984
CSF neurochemistry in depressed, manic, and schizophrenic patients compared with that of normal controls.
    The American journal of psychiatry, 1984, Volume: 141, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Calcium; Choline; Depressive Disorder; Femal

1984
Short- and long-term effects of GABA and dopamine neurons during treatment with sulpiride.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Cyclic AMP; Cyclic GMP; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Neurons; Prola

1980
Neuroleptic-induced decrease in plasma homovanillic acid and antipsychotic activity in schizophrenic patients.
    Science (New York, N.Y.), 1984, Aug-31, Volume: 225, Issue:4665

    Topics: Adult; Dopamine; Female; Fluphenazine; Homovanillic Acid; Humans; Male; Phenylacetates; Schizophreni

1984
Seasonal variation in human central dopamine activity.
    Psychiatry research, 1984, Volume: 11, Issue:2

    Topics: Adult; Blinking; Brain Chemistry; Dopamine; Female; Homovanillic Acid; Humans; Hypothalamus; Male; M

1984
Plasma catecholamine metabolites and early response to haloperidol.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Female; Glycols; Haloperidol; Homovanillic Acid; Hospitalization;

1984
[Various features of dopamine metabolism in schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:9

    Topics: Dihydroxyphenylalanine; Dopamine; Epinephrine; Homovanillic Acid; Humans; Norepinephrine; Schizophre

1981
[Use of haloperidol in high doses in schizophrenia. Clinical, biochemical and pharmacokinetic study].
    L'Encephale, 1982, Volume: 8, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Haloperidol; Homovanillic

1982
Determination of p-hydroxyphenylacetic acid in cerebrospinal fluid by high-performance liquid chromatography with electrochemical detection.
    Clinica chimica acta; international journal of clinical chemistry, 1982, Aug-04, Volume: 123, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Aged; Child; Child, Preschool; Chromatography, Ge

1982
Conditioned dopaminergic activity.
    Biological psychiatry, 1982, Volume: 17, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Conditioning, Classical; Cues; Dextroamphet

1982
[Biochemical analysis of dopaminergic nerve terminals of post-mortem brain from schizophrenic patients (author's transl)].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1981, Volume: 83, Issue:7

    Topics: Adult; Aged; Brain Chemistry; Dopamine; Female; Homovanillic Acid; Humans; Male; Middle Aged; Nerve

1981
CSF monoamine metabolites in depression and schizophrenia.
    The American journal of psychiatry, 1980, Volume: 137, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mal

1980
Schizophrenia: gender, family risk, and plasma homovanillic acid.
    American journal of medical genetics, 1995, Apr-24, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Family; Female; Haloperidol; Homovanillic Acid; Humans; Male; Risk Factors; Schiz

1995
An association between low levels of 5-HIAA and HVA in cerebrospinal fluid and early mortality in a diagnostically mixed psychiatric sample.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 163

    Topics: Adult; Aged; Cause of Death; Depressive Disorder; Follow-Up Studies; Homovanillic Acid; Hospital Rec

1993
Noradrenergic activity and prediction of psychotic relapse following haloperidol withdrawal in schizophrenia.
    The American journal of psychiatry, 1994, Volume: 151, Issue:3

    Topics: Adult; Chromogranin A; Chromogranins; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac

1994
Neuropsychological correlates of central monoamine function in chronic schizophrenia: relationship between CSF metabolites and cognitive function.
    Schizophrenia research, 1994, Volume: 11, Issue:3

    Topics: Adult; Cerebral Cortex; Cognition Disorders; Discrimination Learning; Dopamine; Homovanillic Acid; H

1994
Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:2

    Topics: Adult; Biogenic Monoamines; Chronic Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic

1994
CSF concentrations of neurotensin in schizophrenia: an investigation of clinical and biochemical correlates.
    Schizophrenia research, 1994, Volume: 12, Issue:1

    Topics: Adult; Female; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydrox

1994
Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid;

1994
Clozapine therapy and increases in homovanillic acid.
    Archives of general psychiatry, 1995, Volume: 52, Issue:3

    Topics: Chromatography, High Pressure Liquid; Clozapine; Dopamine; Homovanillic Acid; Humans; Hydroxyindolea

1995
Behavioral vs biochemical prediction of clinical stability following haloperidol withdrawal in schizophrenia.
    Archives of general psychiatry, 1995, Volume: 52, Issue:8

    Topics: Adult; Age of Onset; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Logistic Mode

1995
Decreased DOPAC in the anterior cingulate cortex of individuals with schizophrenia.
    Biological psychiatry, 1995, Jul-01, Volume: 38, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Age Factors; Aged; Antipsychotic Agents; Autopsy; Female; Gas

1995
Schizophrenic patients with deficit syndrome have higher plasma homovanillic acid concentrations and ventricular enlargement.
    Biological psychiatry, 1995, Jul-01, Volume: 38, Issue:1

    Topics: Adult; Cerebral Ventricles; Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Humans;

1995
CSF 5-HIAA and atmospheric pressure: failure to replicate.
    Biological psychiatry, 1993, Jan-01, Volume: 33, Issue:1

    Topics: Atmospheric Pressure; Body Height; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacet

1993
Effect of neuroleptic medication on cerebrospinal fluid monoamine metabolite concentrations in schizophrenia. Serotonin-dopamine interactions as a target for treatment.
    Archives of general psychiatry, 1993, Volume: 50, Issue:8

    Topics: Adult; Dopamine; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Psychiatric

1993
Monoamine neurotransmitter interactions in drug-free and neuroleptic-treated schizophrenics.
    Archives of general psychiatry, 1993, Volume: 50, Issue:8

    Topics: Adult; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Meth

1993
Are monoamine metabolites in cerebrospinal fluid worth measuring?
    Archives of general psychiatry, 1993, Volume: 50, Issue:8

    Topics: Animals; Brain; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Met

1993
Low cerebrospinal fluid homovanillic acid-5-hydroxyindoleacetic acid ratio predicts clozapine efficacy: a replication.
    Archives of general psychiatry, 1993, Volume: 50, Issue:8

    Topics: Clozapine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Prospective Studies; Psychiatric Sta

1993
Gender differences in onset of illness, treatment response, course, and biologic indexes in first-episode schizophrenic patients.
    The American journal of psychiatry, 1995, Volume: 152, Issue:5

    Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Chronic Disease; Female; Follow-Up Studies; H

1995
Low concentrations of serum tyrosine in neuroleptic-free schizophrenics with an early onset.
    Schizophrenia research, 1995, Volume: 14, Issue:3

    Topics: Adult; Age of Onset; Brain; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Male; M

1995
Assessment of the central dopaminergic index of plasma HVA in schizophrenia.
    Schizophrenia bulletin, 1995, Volume: 21, Issue:1

    Topics: Brain; Debrisoquin; Dopamine; Homovanillic Acid; Humans; Male; Methoxyhydroxyphenylglycol; Neurons;

1995
Persistent psychosis after reduction in pre- and post-synaptic dopaminergic function.
    Journal of neural transmission. General section, 1994, Volume: 95, Issue:1

    Topics: Adult; alpha-Methyltyrosine; Antipsychotic Agents; Basal Ganglia Diseases; Dopamine; Drug Resistance

1994
Monoamine activity reflected in urine of young patients with obsessive compulsive disorder, psychosis with and without reality distortion and healthy subjects: an explorative analysis.
    Journal of neural transmission. General section, 1994, Volume: 96, Issue:2

    Topics: Adolescent; Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Creatinine; Dopamine; Epine

1994
Longitudinal changes in symptoms and plasma homovanillic acid levels in chronically medicated schizophrenic patients.
    Biological psychiatry, 1994, Nov-15, Volume: 36, Issue:10

    Topics: Adult; Antipsychotic Agents; Arousal; Chronic Disease; Homovanillic Acid; Hospitalization; Humans; L

1994
Plasma homovanillic acid levels in first-episode schizophrenia. Psychopathology and treatment response.
    Archives of general psychiatry, 1994, Volume: 51, Issue:2

    Topics: Adult; Antipsychotic Agents; Confidence Intervals; Female; Homovanillic Acid; Humans; Male; Psychiat

1994
A comparison of plasma homovanillic acid in the deficit and nondeficit subtypes of schizophrenia.
    Biological psychiatry, 1994, Aug-15, Volume: 36, Issue:4

    Topics: Adult; Arousal; Female; Homovanillic Acid; Humans; Male; Psychiatric Status Rating Scales; Schizophr

1994
Disposition of clozapine and desmethylclozapine in schizophrenic patients.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:4

    Topics: Adult; Chronic Disease; Clozapine; Dextromethorphan; Half-Life; Homovanillic Acid; Humans; Male; Met

1994
Auditory sensory gating, hippocampal volume, and catecholamine metabolism in schizophrenics and their siblings.
    Schizophrenia research, 1994, Volume: 12, Issue:2

    Topics: Acoustic Stimulation; Adult; Amygdala; Arousal; Attention; Catecholamines; Chronic Disease; Dopamine

1994
B-HT 920, a dopamine D2 agonist, in the treatment of negative symptoms of chronic schizophrenia.
    Biological psychiatry, 1993, May-15, Volume: 33, Issue:10

    Topics: Arousal; Azepines; Brain; Dopamine Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induce

1993
Studies on neurochemical heterogeneity in healthy parents of schizophrenic patients.
    Schizophrenia research, 1993, Volume: 10, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Male; Middle Aged; Norepinephr

1993
Homovanillic acid in the cerebrospinal fluid: patterns of response after four weeks of neuroleptic treatment.
    Biological psychiatry, 1993, Aug-01, Volume: 34, Issue:3

    Topics: Adult; Age of Onset; Antipsychotic Agents; Brain; Dopamine; Drug Tolerance; Female; Glutamates; Homo

1993
Psychotic patients with increased plasma HVA and MHPG or increased HVA alone.
    Biological psychiatry, 1993, Oct-15, Volume: 34, Issue:8

    Topics: Adult; Arousal; Female; Homovanillic Acid; Humans; Male; Methoxyhydroxyphenylglycol; Psychiatric Sta

1993
An association between increased concentrations of cerebrospinal fluid dopamine sulfate and higher negative symptom scores in patients with schizophrenia and schizoaffective disorder.
    Biological psychiatry, 1993, Nov-01, Volume: 34, Issue:9

    Topics: Chronic Disease; Dopamine; Homovanillic Acid; Humans; Psychiatric Status Rating Scales; Psychotic Di

1993
Influence of renal clearance on peripheral homovanillic acid measurements in healthy subjects and schizophrenic patients.
    Schizophrenia research, 1993, Volume: 11, Issue:1

    Topics: Adult; Brain; Creatinine; Dopamine; Glomerular Filtration Rate; Homovanillic Acid; Humans; Male; Met

1993
Effects of single dose haloperidol administration on plasma homovanillic acid levels in normal subjects.
    Psychiatry research, 1993, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Circadian Rhythm; Dopamine; Haloperidol; Homovanillic Acid; Humans; Male; Schizop

1993
Haloperidol response and plasma catecholamines and their metabolites.
    Schizophrenia research, 1993, Volume: 10, Issue:1

    Topics: Adult; Catecholamines; Dopamine; Female; Haloperidol; Homovanillic Acid; Humans; Longitudinal Studie

1993
Haloperidol response and plasma catecholamines and their metabolites.
    Schizophrenia research, 1993, Volume: 10, Issue:1

    Topics: Adult; Catecholamines; Dopamine; Female; Haloperidol; Homovanillic Acid; Humans; Longitudinal Studie

1993
Haloperidol response and plasma catecholamines and their metabolites.
    Schizophrenia research, 1993, Volume: 10, Issue:1

    Topics: Adult; Catecholamines; Dopamine; Female; Haloperidol; Homovanillic Acid; Humans; Longitudinal Studie

1993
Haloperidol response and plasma catecholamines and their metabolites.
    Schizophrenia research, 1993, Volume: 10, Issue:1

    Topics: Adult; Catecholamines; Dopamine; Female; Haloperidol; Homovanillic Acid; Humans; Longitudinal Studie

1993
Serum homovanillic acid levels in schizophrenic patients and normal control subjects.
    Psychiatry research, 1993, Volume: 48, Issue:2

    Topics: Adult; Homovanillic Acid; Humans; Male; Psychiatric Status Rating Scales; Reference Values; Schizoph

1993
On the value of measuring dopamine, norepinephrine and their metabolites in schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:2

    Topics: Dopamine; Homovanillic Acid; Humans; Norepinephrine; Schizophrenia

1993
Treatment with clozapine and its effect on plasma homovanillic acid and norepinephrine concentrations in schizophrenia.
    Psychiatry research, 1993, Volume: 46, Issue:2

    Topics: Adult; Clozapine; Dopamine; Female; Homovanillic Acid; Humans; Male; Norepinephrine; Receptors, Adre

1993
Effects of haloperidol decanoate on plasma homovanillic acid in chronic schizophrenic patients.
    Biological psychiatry, 1993, Apr-01, Volume: 33, Issue:7

    Topics: Adult; Brain; Chronic Disease; Delayed-Action Preparations; Female; Haloperidol; Homovanillic Acid;

1993
Plasma prolactin and plasma homovanillic acid: predictors of clinical response in schizophrenia.
    Biological psychiatry, 1995, Aug-15, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Female; Haloperidol; Homovanillic Acid; Humans; Male; Prola

1995
The relationship between urine excretion and biogenic amines and their metabolites in cerebrospinal fluid of schizophrenic patients.
    Schizophrenia research, 1996, Volume: 19, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Biogenic Amines; Chronic Disease; Drinking; Female; Histamine

1996
Exaggerated responsivity of brain dopaminergic system activity in schizophrenia: a preliminary finding of increased variance of plasma homovanillic acid level in a chronic patient.
    Schizophrenia research, 1996, Volume: 20, Issue:1-2

    Topics: Adult; Brain; Chronic Disease; Dopamine; Female; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyi

1996
Dopamine turnover in schizophrenia before and after haloperidol withdrawal. CSF, plasma, and urine studies.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1996, Volume: 15, Issue:1

    Topics: Adult; Dopamine; Haloperidol; Homovanillic Acid; Humans; Male; Schizophrenia

1996
Impact of neuroleptic medications on continuous performance test measures in schizophrenia.
    Biological psychiatry, 1996, May-15, Volume: 39, Issue:10

    Topics: Adult; Antipsychotic Agents; Attention; Female; Homovanillic Acid; Humans; Male; Middle Aged; Schizo

1996
Tyrosine transport as an indicator of cell membrane dysfunction in schizophrenia.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 55, Issue:1-2

    Topics: Amino Acids; Biological Transport; Biopsy; Carbon Radioisotopes; Female; Fibroblasts; Homovanillic A

1996
Negative symptoms in nondeficit syndrome respond to neuroleptic treatment with changes in plasma homovanillic acid concentrations.
    Journal of psychiatry & neuroscience : JPN, 1996, Volume: 21, Issue:3

    Topics: Adult; Aged; Antipsychotic Agents; Depression; Dopamine D2 Receptor Antagonists; Dose-Response Relat

1996
Sex differences in plasma homovanillic acid levels in schizophrenia and normal controls: relation to neuroleptic resistance.
    Biological psychiatry, 1997, Mar-01, Volume: 41, Issue:5

    Topics: Antipsychotic Agents; Female; Homovanillic Acid; Humans; Male; Prolactin; Psychiatric Status Rating

1997
Schizophrenia, psychosis, and cerebral spinal fluid homovanillic acid concentrations.
    Schizophrenia bulletin, 1997, Volume: 23, Issue:1

    Topics: Adult; Aged; Brain; Dopamine; Homovanillic Acid; Humans; Male; Middle Aged; Psychiatric Status Ratin

1997
Association of DNA polymorphism in the first intron of the tyrosine hydroxylase gene with disturbances of the catecholaminergic system in schizophrenia.
    Schizophrenia research, 1997, Feb-28, Volume: 23, Issue:3

    Topics: Adult; Analysis of Variance; Case-Control Studies; Catecholamines; Chi-Square Distribution; Female;

1997
A biomodal distribution of plasma HVA/MHPG in the psychoses.
    Psychiatry research, 1997, Mar-24, Volume: 69, Issue:2-3

    Topics: Adult; Female; Homovanillic Acid; Humans; Male; Methoxyhydroxyphenylglycol; Psychotic Disorders; Sch

1997
Prediction of short-term changes in symptom severity by baseline plasma homovanillic acid levels in schizophrenic patients receiving clozapine.
    Psychiatry research, 1997, Mar-24, Volume: 69, Issue:2-3

    Topics: Adult; Antipsychotic Agents; Clozapine; Homovanillic Acid; Humans; Male; Schizophrenia; Treatment Ou

1997
Changes in symptoms and plasma homovanillic acid with amantadine hydrochloride in chronic schizophrenia.
    Biological psychiatry, 1997, May-15, Volume: 41, Issue:10

    Topics: Adult; Aged; Amantadine; Chronic Disease; Dopamine Agents; Dose-Response Relationship, Drug; Drug Ad

1997
Improvement of schizophrenic symptoms and changes in plasma HVA concentrations, plasma anti-D2 and anti-5-HT2 receptor activities with clozapine.
    Psychiatry and clinical neurosciences, 1996, Volume: 50, Issue:5

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Clozapine; Dopamine; Homovanillic Acid; Humans; Male;

1996
Evolution of plasma homovanillic acid (HVA) in chronic schizophrenic patients treated with haloperidol.
    Acta psychiatrica Scandinavica, 1998, Volume: 97, Issue:6

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Dopamine Antagonists; Dose-Response Relationship,

1998
Failure to replicate an association between a rare allele of a tyrosine hydroxylase gene microsatellite and schizophrenia.
    European archives of psychiatry and clinical neuroscience, 1998, Volume: 248, Issue:2

    Topics: Alleles; Gene Expression Regulation, Enzymologic; Gene Frequency; Homovanillic Acid; Humans; Hydroxy

1998
Neurochemical variables in schizophrenic patients during switching from neuroleptics to clozapine.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:7

    Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Clozapine; Homovanillic Acid; Humans; Hydro

1998
CSF levels of HVA and 5-HIAA in drug-free schizophrenic patients and healthy controls: a prospective study focused on their predictive value for outcome in schizophrenia.
    Psychiatry research, 1998, Nov-16, Volume: 81, Issue:2

    Topics: Adolescent; Adult; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid

1998
Plasma catecholamine metabolites as markers for psychosis and antipsychotic response in schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:6

    Topics: Adult; Antipsychotic Agents; Biomarkers; Bipolar Disorder; Catecholamines; Homovanillic Acid; Humans

1999
Genetic antecedents of dopamine dysfunction in schizophrenia.
    Biological psychiatry, 1999, May-01, Volume: 45, Issue:9

    Topics: Adult; Chromatography, High Pressure Liquid; Dopamine; Female; Homovanillic Acid; Humans; Male; Midd

1999
[Study on dopamine metabolite in cerebrospinal fluid of schizophrenics and epilepsics].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 1998, Volume: 23, Issue:2

    Topics: Adult; Dopamine; Epilepsy; Female; Homovanillic Acid; Humans; Male; Middle Aged; Schizophrenia

1998
Plasma homovanillic acid in the prodromal phase of schizophrenia.
    Biological psychiatry, 2000, Mar-01, Volume: 47, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Biomarkers; Case-Control Studies; Dopamine; Homovanillic Acid; Hum

2000
Neonatal lesions of the left entorhinal cortex affect dopamine metabolism in the rat brain.
    Brain research, 2000, Mar-31, Volume: 860, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Animals, Newborn; Brain; Caudate Nucleus; Disease

2000
Season of birth variations in dimensions of functioning evaluated by the diagnostic interview for borderline patients.
    Neuropsychobiology, 2000, Volume: 41, Issue:3

    Topics: Anxiety Disorders; Biogenic Monoamines; Birth Certificates; Borderline Personality Disorder; Homovan

2000
Relationships between interleukins, neurotransmitters and psychopathology in drug-free male schizophrenics.
    Schizophrenia research, 2000, Sep-01, Volume: 44, Issue:3

    Topics: Adult; Antipsychotic Agents; Dopamine; Enzyme-Linked Immunosorbent Assay; Haloperidol; Homovanillic

2000
Schizophrenia and plasma homovanillic acid in response to mental stress: methodological considerations.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:3

    Topics: Circadian Rhythm; Homovanillic Acid; Humans; Schizophrenia; Stress, Psychological

2000
Heterogeneity of response to antipsychotics from multiple disorders in the schizophrenia spectrum.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:12

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Biomarkers; Cerebral Ventricles; Child; Family; Homov

2000
Continuous phencyclidine treatment induces schizophrenia-like hyperreactivity of striatal dopamine release.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Central Nervous System Stimulants; Corpus Stri

2001
Relationship of symptomatology, gender, and antipsychotic drug treatment with plasma homovanillic acid in schizophrenia.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:1

    Topics: Adult; Antipsychotic Agents; Chlorpromazine; Female; Homovanillic Acid; Humans; Male; Middle Aged; S

2001
Plasma hormones and catecholamine metabolites in monozygotic twins discordant for psychosis.
    Neuropsychiatry, neuropsychology, and behavioral neurology, 2002, Volume: 15, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adrenocorticotropic Hormone; Adult; Bipolar Disorder; Ca

2002
Transmitter precursors and metabolites in human ventricular cerebrospinal fluid.
    Journal of neurochemistry, 1976, Volume: 26, Issue:3

    Topics: Cerebral Ventricles; Frontal Lobe; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Neurotic Dis

1976
Clinical assessment of dopamine receptor blockade.
    Life sciences, 1978, Aug-07, Volume: 23, Issue:5

    Topics: Antipsychotic Agents; Homovanillic Acid; Humans; Methoxyhydroxyphenylglycol; Prolactin; Receptors, D

1978
Antipsychotic drug action in schizophrenic patients: effect on cortical dopamine metabolism after long-term treatment.
    Science (New York, N.Y.), 1979, Sep-28, Volume: 205, Issue:4413

    Topics: 3,4-Dihydroxyphenylacetic Acid; Antipsychotic Agents; Brain; Cerebral Cortex; Dopamine; Homovanillic

1979
Cerebrospinal fluid monoamine metabolites and cyclic nucleotides in chronic schizophrenic patients with tardive dyskinesia or drug-induced tremor.
    Biological psychiatry, 1979, Volume: 14, Issue:3

    Topics: Adult; Chronic Disease; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Ho

1979
The dopamine hypothesis of schizophrenia revisited.
    Psychoneuroendocrinology, 1979, Volume: 4, Issue:1

    Topics: Antipsychotic Agents; Cerebral Cortex; Corpus Striatum; Dopamine; Dopamine beta-Hydroxylase; gamma-A

1979
Dopamine and schizophrenia.
    Lancet (London, England), 1976, Sep-11, Volume: 2, Issue:7985

    Topics: Animals; Chlorpromazine; Corpus Striatum; Dopamine; Dopamine Antagonists; Fluphenazine; Homovanillic

1976
Dopamine and schizophrenia.
    Lancet (London, England), 1976, Oct-02, Volume: 2, Issue:7988

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Homovanillic Acid; Humans; Rats;

1976
Dopamine and schizophrenia.
    Lancet (London, England), 1977, Jan-08, Volume: 1, Issue:8002

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Corpus Striatum; Drug Evaluation; Hom

1977
Brain biochemistry in schizophrenia.
    Lancet (London, England), 1978, Jan-07, Volume: 1, Issue:8054

    Topics: Brain; Dopamine; Glutamate Decarboxylase; Homovanillic Acid; Humans; Schizophrenia

1978
Neuroleptic drugs and the dopamine hypothesis.
    Lancet (London, England), 1979, Apr-28, Volume: 1, Issue:8122

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Limbi

1979
Relationships between clinical and biochemical effects of melperone and thiothixene in psychotic women.
    Archiv fur Psychiatrie und Nervenkrankheiten, 1979, Volume: 227, Issue:3

    Topics: Butyrophenones; Diazepam; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydrox

1979
Thiethylperazine; clinical antipsychotic efficacy and correlation with potency in predictive systems.
    Archives of general psychiatry, 1978, Volume: 35, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Corpus Striatum; Dopamine; Dopamine Anta

1978
Reduction of MOPEG levels in cerebrospinal fluid of psychotic women after electroconvulsive treatment.
    Psychopharmacology, 1979, Aug-08, Volume: 64, Issue:2

    Topics: Biogenic Amines; Electroconvulsive Therapy; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindol

1979
Interactions between central monoaminergic systems: dopamine-serotonin.
    Journal of neurology, neurosurgery, and psychiatry, 1979, Volume: 42, Issue:12

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depression; Dopamine; Dyskinesia, Drug-Induced; Female; H

1979
Cerebrospinal fluid cyclic AMP and acid monoamine metabolites following probenecid: studies in psychiatric patients.
    Psychopharmacology, 1979, Mar-29, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Biogenic Amines; Chlorpromazine; Cyclic AMP; Depression; Female; Homovanill

1979
Effect of probenecid on the concentration of the lumbar cerebrospinal fluid acidic metabolites of tyramine, octopamine, dopamine and norepinephrine.
    Biochemical pharmacology, 1977, Apr-01, Volume: 26, Issue:7

    Topics: Dopamine; Female; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Male; Norepinephr

1977
Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology.
    European neurology, 1979, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Child; Dopamine; Epilepsy, Temporal Lobe; Homovanillic Acid; Humans; Hydroxyindol

1979
Monoamine metabolite levels in cerebrospinal fluid and brain atrophy in lobotomized schizophrenic patients.
    Annals of clinical research, 1979, Volume: 11, Issue:1

    Topics: Atrophy; Brain Diseases; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

1979
Monoamines and monoamine metabolites in brains from demented schizophrenics.
    Acta psychiatrica Scandinavica, 1979, Volume: 60, Issue:1

    Topics: Brain; Brain Chemistry; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

1979
Dopamine and homovanillic acid concentrations in the post-mortem brain in schizophrenia [proceedings].
    The Journal of physiology, 1979, Volume: 293

    Topics: Brain; Caudate Nucleus; Dopamine; Homovanillic Acid; Humans; Nucleus Accumbens; Phenylacetates; Puta

1979
Pathophysiological studies on schizophrenia with special reference to homovanillic acid concentration in cerebrospin fluid.
    Bulletin of the Osaka Medical School, 1979, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Female; Haloperidol; Homovanillic Acid; Humans; Male; Phenylacetates; Schizophren

1979
Lithium: clinical effects and cerebrospinal fluid acid monoamine metabolites.
    Communications in psychopharmacology, 1977, Volume: 1, Issue:2

    Topics: Adult; Affective Symptoms; Aged; Biogenic Amines; Bipolar Disorder; Depression; Electroencephalograp

1977
MAO activity, csf amine metabolites, and drug-free improvement in schizophrenia.
    The American journal of psychiatry, 1978, Volume: 135, Issue:5

    Topics: Adolescent; Adult; Blood Platelets; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mal

1978
CSF acid monoamine metabolites in psychotic syndromes: what might they signify?
    Biological psychiatry, 1978, Volume: 13, Issue:3

    Topics: Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Prognosis; Psychotic Disorders;

1978
Effect of baclofen on cerebrospinal-fluid levels of 5-hydroxyindoleacetic acid and homovanillic acid.
    The New England journal of medicine, 1977, Feb-24, Volume: 296, Issue:8

    Topics: Adult; Aminobutyrates; Baclofen; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

1977
The significance of dopamine for the mode of action of neuroleptics and the pathogenesis of schizophrenia.
    The British journal of psychiatry : the journal of mental science, 1977, Volume: 130

    Topics: Dopamine; Homovanillic Acid; Humans; Probenecid; Schizophrenia; Tranquilizing Agents

1977
Nonstriatal dopaminergic neurons: Section XI. Dopaminergic neurons and mental diseases: Introduction: dopaminergic neurons and mental diseases.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: Apomorphine; Bromocriptine; Catecholamines; Depression; Dopamine; Homovanillic Acid; Humans; Levodop

1977
The Parkinsonian syndrome and its dopamine correlates.
    Advances in experimental medicine and biology, 1977, Volume: 90

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Dopamine; Extrapyramidal Tracts; Female; Homovanillic A

1977
CSF amine metabolites, clinical symptoms, and body movement in psychiatric patients.
    Biological psychiatry, 1976, Volume: 11, Issue:4

    Topics: Adult; Anger; Anxiety; Arousal; Brain; Depression; Female; Homovanillic Acid; Humans; Hydroxyindolea

1976
CSF acid monoamine metabolities as a possible reflection of central MAO activity in chronic schizophrenia.
    Biological psychiatry, 1976, Volume: 11, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Bipolar Disorder; Chronic Disease; Female; Homovanillic Acid; Huma

1976
Clinical and biochemical parameters during neuroleptic treatment. I. Investigations with haloperidol.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1976, Volume: 9, Issue:1

    Topics: Adult; Female; Hallucinations; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mal

1976
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
    Psychological medicine, 1976, Volume: 6, Issue:3

    Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanilli

1976
[Differences in serotonin and dopamine metabolism in psychopathy and sluggish schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:11

    Topics: Adult; Antisocial Personality Disorder; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Aci

1976
Thioridazine: central dopamine turnover and clinical effects of antipsychotic drugs.
    Clinical pharmacology and therapeutics, 1975, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Midd

1975
Role of biogenic amines in certain pathological conditions.
    Brain research, 1975, Apr-11, Volume: 87, Issue:2-3

    Topics: Acute Disease; Adult; Aggression; Biogenic Amines; Bipolar Disorder; Chlorpromazine; Chronic Disease

1975
Cerebrospinal fluid amine metabolites in acute schizophrenia.
    Archives of general psychiatry, 1975, Volume: 32, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Amines; Bipolar Disorder; Dopamine; Homovanillic Acid; Humans; Hyd

1975
Time-dependent effects of phenothiazines on dopamine turnover in psychiatric patients.
    Science (New York, N.Y.), 1975, Oct-31, Volume: 190, Issue:4213

    Topics: Bipolar Disorder; Brain; Chlorpromazine; Dopamine; Homovanillic Acid; Humans; Schizophrenia; Thiorid

1975
Central noradrenergic function in man: vanillylmandelic acid in CSF.
    Brain research, 1975, Dec-05, Volume: 99, Issue:2

    Topics: Acute Disease; Affective Symptoms; Bipolar Disorder; Depression; Homovanillic Acid; Humans; Hydroxyi

1975
Cerebrospinal fluid amine metabolites in affective illness and schizophrenia: clinical and pharmacological studies.
    Psychopharmacology communications, 1975, Volume: 1, Issue:6

    Topics: Affective Symptoms; Amines; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipram

1975
Relationship of plasma HVA and treatment response in a large series of patients with schizophrenia.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Antipsychotic Agents; Homovanillic Acid; Humans; Prolactin; Psychiatric Status Rating Scales; Schizo

1992
Measurements of plasma homovanillic acid in schizophrenic patients.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Antipsychotic Agents; Homovanillic Acid; Humans; Schizophrenia

1992
Studies on concentrations of NA and HVA and activity of DBH in the serum from schizophrenic patients, first-degree relatives and normal subjects.
    Schizophrenia research, 1992, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Dopamine beta-Hydroxylase; Female; Ho

1992
Electrodermal orienting response and central nervous system dopamine and serotonin activity in schizophrenia.
    The Journal of nervous and mental disease, 1992, Volume: 180, Issue:5

    Topics: Acoustic Stimulation; Acute Disease; Adolescent; Adult; Brain; Dopamine; Galvanic Skin Response; Hom

1992
Biogenic amine metabolites in plasma of drug-naive schizophrenic patients: associations with symptomatology.
    Biological psychiatry, 1992, Aug-01, Volume: 32, Issue:3

    Topics: Adult; Arousal; Chromatography, High Pressure Liquid; Homovanillic Acid; Hospitalization; Humans; Hy

1992
Dopamine in schizophrenia.
    The American journal of psychiatry, 1992, Volume: 149, Issue:11

    Topics: Dopamine; Frontal Lobe; Homovanillic Acid; Humans; Limbic System; Schizophrenia; Schizophrenic Psych

1992
Auditory sensory gating and catecholamine metabolism in schizophrenic and normal subjects.
    Psychiatry research, 1992, Volume: 44, Issue:1

    Topics: Acoustic Stimulation; Adult; Arousal; Attention; Auditory Pathways; Cerebral Cortex; Electroencephal

1992
Lithium in combination with perphenazine: effect on plasma monoamine metabolites.
    Biological psychiatry, 1992, Dec-15, Volume: 32, Issue:12

    Topics: Adult; Aged; Bipolar Disorder; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Lithium

1992
Plasma homovanillic acid and other predictors of clozapine response.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Clozapine; Fluphenazine; Homovanillic Acid; Humans; Schizophrenia

1992
Plasma prolactin and homovanillic acid as markers for psychopathology and abnormal movements during maintenance haloperidol treatment in male patients with schizophrenia.
    Psychiatry research, 1992, Volume: 41, Issue:3

    Topics: Adult; Aged; Apomorphine; Brain; Dyskinesia, Drug-Induced; Haloperidol; Homovanillic Acid; Humans; M

1992
Changes in plasma homovanillic acid concentrations in schizophrenic patients following neuroleptic discontinuation.
    Archives of general psychiatry, 1991, Volume: 48, Issue:1

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Dopamine; Homovanillic Acid; Humans; Psychiatric Statu

1991
Characteristics of psychotic inpatients with high or low HVA levels at admission.
    The American journal of psychiatry, 1991, Volume: 148, Issue:2

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Female; Gas Chromatography-Mass Spectrometry; Homovan

1991
Plasma homovanillic acid and prognosis in schizophrenia.
    Biological psychiatry, 1991, Jan-15, Volume: 29, Issue:2

    Topics: Antipsychotic Agents; Follow-Up Studies; Homovanillic Acid; Hospitalization; Humans; Outcome and Pro

1991
Norepinephrine in acute exacerbations of chronic schizophrenia. Negative symptoms revisited.
    Archives of general psychiatry, 1990, Volume: 47, Issue:2

    Topics: Acute Disease; Adult; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methox

1990
Neuroleptic malignant syndrome: a study of CSF monoamine metabolism.
    Biological psychiatry, 1990, Feb-01, Volume: 27, Issue:3

    Topics: Adult; Biogenic Monoamines; Bipolar Disorder; Depressive Disorder; Female; Homovanillic Acid; Humans

1990
Concentration gradients for HVA, 5-HIAA, ascorbic acid, and uric acid in cerebrospinal fluid.
    Biological psychiatry, 1990, Apr-15, Volume: 27, Issue:8

    Topics: Adult; Aged; Alcohol Amnestic Disorder; Ascorbic Acid; Brain; Dementia; Female; Homovanillic Acid; H

1990
Cerebrospinal fluid and plasma monoamine metabolites and their relation to psychosis. Implications for regional brain dysfunction in schizophrenia.
    Archives of general psychiatry, 1990, Volume: 47, Issue:7

    Topics: Adult; Brain; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhyd

1990
Effects of mianserin on negative symptoms in schizophrenia.
    International clinical psychopharmacology, 1990, Volume: 5, Issue:2

    Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Brain; Chronic Disease; Drug Therapy, Combination

1990
5-HIAA in cerebrospinal fluid and deficit schizophrenic characteristics.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 156

    Topics: Adult; Cognition; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Psychiatric Status Rating Sca

1990
Relationship between abnormal brainstem auditory-evoked potentials and subnormal CSF levels of HVA and 5-HIAA in first-episode schizophrenic patients.
    Biological psychiatry, 1990, Sep-01, Volume: 28, Issue:5

    Topics: Adult; Brain Stem; Evoked Potentials, Auditory, Brain Stem; Female; Homovanillic Acid; Humans; Hydro

1990
Intercorrelations among monoamine metabolite concentrations in human lumbar CSF are not due to a shared acid transport system.
    Biological psychiatry, 1990, Oct-01, Volume: 28, Issue:7

    Topics: Acid-Base Equilibrium; Administration, Oral; Blood-Brain Barrier; Depressive Disorder; Dose-Response

1990
Lateral ventricle-brain ratio and balance between CSF HVA and 5-HIAA in schizophrenia.
    The American journal of psychiatry, 1991, Volume: 148, Issue:9

    Topics: Adult; Age Factors; Bipolar Disorder; Body Height; Body Weight; Brain; Brain Chemistry; Cerebral Ven

1991
Regional brain glucose metabolism: correlations to biochemical measures and anxiety in patients with schizophrenia.
    Psychiatry research, 1991, Volume: 40, Issue:2

    Topics: Adult; Anxiety; Arousal; Blood Glucose; Brain; Brain Mapping; Dominance, Cerebral; Energy Metabolism

1991
CSF chromogranin A-like immunoreactivity in schizophrenia. Assessment of clinical and biochemical relationships.
    Schizophrenia research, 1991, Volume: 6, Issue:1

    Topics: Adult; Arousal; Atrophy; Brain; Chromogranin A; Chromogranins; Haloperidol; Homovanillic Acid; Human

1991
[Plasma homovanillic acid level inpatients with deficit forms of schizophrenics].
    Presse medicale (Paris, France : 1983), 1991, Nov-23, Volume: 20, Issue:39

    Topics: Homovanillic Acid; Humans; Immunologic Deficiency Syndromes; Schizophrenia

1991
Effects of neuroleptic treatment on symptoms of schizophrenia and plasma homovanillic acid concentrations.
    Archives of general psychiatry, 1991, Volume: 48, Issue:10

    Topics: Administration, Oral; Adult; Chronic Disease; Depression, Chemical; Dopamine; Dopamine Antagonists;

1991
Plasma free homovanillic acid (HVA) as a predictor of clinical response in acute psychosis.
    Biological psychiatry, 1991, Sep-01, Volume: 30, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Bipolar Disorder; Chromatography, High Pressure Liquid; Depressive

1991
MMPI measures of impulsivity and depression correlate with CSF 5-HIAA and HVA in depression but not schizophrenia.
    Journal of affective disorders, 1991, Volume: 22, Issue:4

    Topics: Adult; Depressive Disorder; Homovanillic Acid; Humans; Impulsive Behavior; Male; Middle Aged; MMPI;

1991
Psychotogenic drug use and neuroleptic response.
    Schizophrenia bulletin, 1990, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Haloperidol; Homovan

1990
Psychotogenic drug use and neuroleptic response.
    Schizophrenia bulletin, 1990, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Haloperidol; Homovan

1990
Psychotogenic drug use and neuroleptic response.
    Schizophrenia bulletin, 1990, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Haloperidol; Homovan

1990
Psychotogenic drug use and neuroleptic response.
    Schizophrenia bulletin, 1990, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Haloperidol; Homovan

1990
Increments in plasma homovanillic acid concentrations after neuroleptic discontinuation are associated with worsening of schizophrenic symptoms.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:6

    Topics: Adult; Antipsychotic Agents; Drug Administration Schedule; Homovanillic Acid; Humans; Male; Schizoph

1990
Relation of CSF neurotensin concentrations to symptoms and drug response of psychotic patients.
    The American journal of psychiatry, 1991, Volume: 148, Issue:4

    Topics: Adult; Female; Haloperidol; Homovanillic Acid; Humans; Lithium; Male; Middle Aged; Neurotensin; Psyc

1991
The acute effects of central- and peripheral-acting dopamine antagonists on plasma HVA in schizophrenic patients.
    Life sciences, 1991, Volume: 48, Issue:14

    Topics: Adult; Debrisoquin; Domperidone; Female; Fluphenazine; Homovanillic Acid; Humans; Male; Receptors, D

1991
Plasma norepinephrine in chronic schizophrenia.
    The American journal of psychiatry, 1990, Volume: 147, Issue:11

    Topics: Adult; Chronic Disease; Female; Homovanillic Acid; Humans; Male; Norepinephrine; Posture; Psychiatri

1990
Correlates of rapid neuroleptic response in male patients with schizophrenia.
    Psychiatry research, 1990, Volume: 33, Issue:2

    Topics: Adult; Haloperidol; Homovanillic Acid; Humans; Male; Neuropsychological Tests; Psychiatric Status Ra

1990
Plasma HVA, tardive dyskinesia and psychotic symptoms in long-term drug-free inpatients with schizophrenia.
    Psychiatry research, 1990, Volume: 33, Issue:3

    Topics: Aged; Chronic Disease; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Male; Middle Aged; Neuro

1990
Plasma HVA in psychiatric patients: longitudinal studies.
    Psychopharmacology bulletin, 1990, Volume: 26, Issue:3

    Topics: Homovanillic Acid; Humans; Longitudinal Studies; Psychiatric Status Rating Scales; Schizophrenia; Sc

1990
Plasma catecholamine metabolites in schizophrenics: evidence for the two-subtype concept.
    Biological psychiatry, 1990, Mar-01, Volume: 27, Issue:5

    Topics: Adult; Female; Glycols; Haloperidol; Homovanillic Acid; Humans; Male; Methoxyhydroxyphenylglycol; Mi

1990
Sensory gating deficits in psychiatric inpatients: relation to catecholamine metabolites in different diagnostic groups.
    Biological psychiatry, 1990, Mar-01, Volume: 27, Issue:5

    Topics: Adult; Arousal; Attention; Bipolar Disorder; Brain; Catecholamines; Depressive Disorder; Evoked Pote

1990
Sensory physiology and catecholamines in schizophrenia and mania.
    Psychiatry research, 1990, Volume: 31, Issue:3

    Topics: Adult; Arousal; Bipolar Disorder; Dopamine; Electroencephalography; Evoked Potentials, Auditory; Fem

1990
Low HVA and normal 5HIAA CSF levels in drug-free schizophrenic patients compared to healthy volunteers: correlations to symptomatology and family history.
    Psychiatry research, 1985, Volume: 14, Issue:4

    Topics: Adult; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylacetates;

1985
CSF monoamine metabolites in chronic schizophrenic patients who attempt suicide.
    Psychological medicine, 1985, Volume: 15, Issue:2

    Topics: Adult; Chronic Disease; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

1985
Plasma amino acids in relation to cerebrospinal fluid monoamine metabolites in schizophrenic patients and healthy controls.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 147

    Topics: Adult; Amino Acids; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydrox

1985
Brain ventricular size and CSF monoamine metabolites in an adolescent inpatient population.
    Psychiatry research, 1985, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Age Factors; Cerebral Ventricles; Child; Dilatation, Pathologic; Female; Homovani

1985
[Monoamine metabolite levels in cerebrospinal fluid of schizophrenic patients].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1985, Volume: 87, Issue:9

    Topics: Adolescent; Adult; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; S

1985
Correlates of lateral ventricular size in chronic schizophrenia, II: biological measures.
    The American journal of psychiatry, 1986, Volume: 143, Issue:9

    Topics: Adult; Apomorphine; Brain; Cerebral Ventricles; Chronic Disease; Growth Hormone; Homovanillic Acid;

1986
Neurochemical findings in the cerebrospinal fluid of schizophrenic patients with tardive dyskinesia and neuroleptic-induced parkinsonism.
    The Japanese journal of psychiatry and neurology, 1986, Volume: 40, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Catecholamines; Dopamine; Dyskinesia, Drug-Induced; Epinephrine;

1986
CSF levels of receptor-active endorphins in schizophrenic patients: correlations with symptomatology and monoamine metabolites.
    Psychiatry research, 1986, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Antipsychotic Agents; Endorphins; Female; Homovanillic Acid; Humans; Hydroxyindol

1986
Cerebrospinal fluid correlates of suicide attempts and aggression.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Aggression; Animals; Bipolar Disorder; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindole

1986
Suicide and aggression in schizophrenia. Neurobiologic correlates.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Aggression; Brain; Cerebral Ventricles; Dexamethasone; Homovanillic Acid; Humans; Hydrocortisone; Hy

1986
Monoamines and their metabolites in cerebrospinal fluid of patients with senile dementia of Alzheimer type using high performance liquid chromatography and gas chromatography-mass spectrometry.
    Acta psychiatrica Scandinavica, 1987, Volume: 75, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biogenic Amines; Chromatography, High Pressure Liquid; G

1987
CSF creatinine in schizophrenia.
    Biological psychiatry, 1988, Mar-15, Volume: 23, Issue:6

    Topics: Adult; Blood-Brain Barrier; Creatinine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid;

1988
The effect of electroconvulsive therapy on CSF amine metabolites in schizophrenic patients.
    The British journal of psychiatry : the journal of mental science, 1988, Volume: 152

    Topics: Adult; Aged; Electroconvulsive Therapy; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleace

1988
Seasonal changes of CSF monoamine metabolites in psychiatric patients: what is the source?
    Psychiatry research, 1988, Volume: 25, Issue:3

    Topics: Bipolar Disorder; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mental D

1988
Corrections to a 1980 article on CSF monoamine metabolites.
    The American journal of psychiatry, 1989, Volume: 146, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic

1989
CSF neurochemical study of tardive dyskinesia.
    Biological psychiatry, 1989, Mar-15, Volume: 25, Issue:6

    Topics: Acetylcholinesterase; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid;

1989
CSF norepinephrine in schizophrenia is elevated prior to relapse after haloperidol withdrawal.
    Biological psychiatry, 1989, Volume: 26, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Chronic Disease; Haloperidol; Homovanillic Acid; Humans

1989
Clozapine pharmacology and tardive dyskinesia.
    Psychopharmacology, 1989, Volume: 99 Suppl

    Topics: Adolescent; Adult; Clozapine; Dibenzazepines; Dyskinesia, Drug-Induced; Epinephrine; Female; Homovan

1989
Plasma HVA, neuroleptics, and dopaminergic plasticity.
    Biological psychiatry, 1989, Volume: 25, Issue:1

    Topics: Antipsychotic Agents; Brain; Chronic Disease; Homovanillic Acid; Humans; Neuronal Plasticity; Recept

1989
Persistence of cyclicity of the plasma dopamine metabolite, homovanillic acid, in neuroleptic treated schizophrenic patients.
    Life sciences, 1989, Volume: 44, Issue:16

    Topics: Adolescent; Adult; Antipsychotic Agents; Circadian Rhythm; Dopamine; Homovanillic Acid; Humans; Hydr

1989
The effect of neuroleptic discontinuation on psychopathology, involuntary movements, and biochemical measures in patients with persistent tardive dyskinesia.
    Biological psychiatry, 1989, Volume: 26, Issue:3

    Topics: Antipsychotic Agents; Brain; Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; F

1989
Plasma homovanillic acid in schizophrenics: supportive evidence for the two-subtype hypothesis.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1989, Volume: 88, Issue:6

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Male; Schizoph

1989
Multivariate analysis of monoamine indices in patients with chronic schizophrenia.
    The Journal of neuropsychiatry and clinical neurosciences, 1989,Summer, Volume: 1, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Brain; Dopamine; Dopamine beta-Hydroxylase; Dyskinesia,

1989
Cerebrospinal fluid magnesium and calcium related to amine metabolites, diagnosis, and suicide attempts.
    Biological psychiatry, 1985, Volume: 20, Issue:2

    Topics: Adjustment Disorders; Adult; Aged; Calcium; Depressive Disorder; Dexamethasone; Female; Homovanillic

1985
Atrophy limited to the third ventricle in chronic schizophrenic patients. Report of a controlled series.
    Archives of general psychiatry, 1985, Volume: 42, Issue:3

    Topics: Adult; Atrophy; Brain; Cerebellum; Cerebral Cortex; Cerebral Ventricles; Female; Homovanillic Acid;

1985
Decrease in dopamine, its metabolites and noradrenaline in cerebrospinal fluid of schizophrenic patients after withdrawal of long-term neuroleptic treatment.
    Psychopharmacology, 1985, Volume: 85, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antipsychotic Agents; Chronic Disease; Dopamine; Female; Halo

1985
Free and conjugated plasma homovanillic acid in schizophrenic patients.
    Biological psychiatry, 1989, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Humans; Male; Mi

1989
Plasma and CSF HVA before and after pharmacological treatment.
    Psychiatry research, 1989, Volume: 28, Issue:1

    Topics: Adult; Brain; Desipramine; Female; Homovanillic Acid; Humans; Lithium; Male; Psychiatric Status Rati

1989
Plasma homovanillic acid as a predictor of response to fluphenazine treatment.
    Psychopharmacology bulletin, 1989, Volume: 25, Issue:1

    Topics: Adult; Fluphenazine; Homovanillic Acid; Humans; Male; Middle Aged; Schizophrenia

1989
Specificity of plasma HVA response to dexamethasone in psychotic depression.
    Psychiatry research, 1989, Volume: 29, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female;

1989
Chemical and structural changes in the brain in patients with movement disorder.
    Psychopharmacology. Supplementum, 1985, Volume: 2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Antipsychotic Agents; Brain; Choline O-Acetyltransfer

1985
Prediction of response to neuroleptic drug therapy in schizophrenia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1985, Volume: 30, Issue:4

    Topics: Antipsychotic Agents; Electroencephalography; Genetic Variation; Homovanillic Acid; Humans; Kinetics

1985
Down-regulation of central dopamine receptors in schizophrenia.
    The American journal of psychiatry, 1985, Volume: 142, Issue:11

    Topics: Adolescent; Adult; Antipsychotic Agents; Apomorphine; Female; Growth Hormone; Homovanillic Acid; Hum

1985
Effects of apomorphine on blood levels of homovanillic acid, growth hormone and prolactin in medicated schizophrenics and healthy control subjects.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:4

    Topics: Adult; Antipsychotic Agents; Apomorphine; Growth Hormone; Homovanillic Acid; Humans; Male; Prolactin

1985
CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment.
    Psychiatry research, 1985, Volume: 16, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antipsychotic Agents; Brain; Chronic Disease; Dopamine; Femal

1985
Changes in mental condition, hyperkinesias and biochemical parameters after withdrawal of chronic neuroleptic treatment.
    Acta psychiatrica Scandinavica, 1985, Volume: 72, Issue:5

    Topics: Adult; Antipsychotic Agents; Dopamine beta-Hydroxylase; Dyskinesia, Drug-Induced; Female; Homovanill

1985
Neuroleptics, dopamine, and schizophrenia.
    The Psychiatric clinics of North America, 1986, Volume: 9, Issue:1

    Topics: Adult; Animals; Antipsychotic Agents; Brain; Dopamine; Fluphenazine; Homovanillic Acid; Humans; Male

1986
Remoxipride in schizophrenia. A preliminary report.
    Acta psychiatrica Scandinavica, 1986, Volume: 74, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzamides; Female; Homovanillic Acid; Humans; Male; Middle Aged; Pilot

1986
[Physiopathologic chemistry of the schizophrenic brain].
    Nihon rinsho. Japanese journal of clinical medicine, 1987, Volume: 45, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Brain; Dopamine; Female; Homovanillic Acid; Humans; Male; Middle Age

1987
Serum homovanillic acid concentrations in carbamazepine-treated chronic schizophrenics.
    Biological psychiatry, 1989, Mar-01, Volume: 25, Issue:5

    Topics: Adult; Carbamazepine; Chronic Disease; Homovanillic Acid; Humans; Male; Receptors, Dopamine; Schizop

1989
An open label trial of raclopride in acute schizophrenia. Confirmation of D2-dopamine receptor occupancy by PET.
    Psychopharmacology, 1988, Volume: 94, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Female; Hemodynamics; Homovanillic Acid; Humans; Male; Middle Aged

1988
Effect of trifluoperazine on CSF and plasma HVA levels in schizophrenic subjects.
    The American journal of psychiatry, 1988, Volume: 145, Issue:11

    Topics: Adult; Dopamine; Female; Homovanillic Acid; Humans; Male; Schizophrenia; Schizophrenic Psychology; T

1988
Dopamine metabolism and disposition in schizophrenic patients. Studies using debrisoquin.
    Archives of general psychiatry, 1988, Volume: 45, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Blood Platelets; Brain; Debrisoquin; Dopamine; Homovani

1988
A comparison of plasma homovanillic acid concentrations in schizophrenic patients and normal controls.
    Archives of general psychiatry, 1988, Volume: 45, Issue:6

    Topics: Adult; Brain; Chronic Disease; Circadian Rhythm; Dopamine; Homovanillic Acid; Hospitalization; Human

1988
Plasma homovanillic acid as a predictor of response to neuroleptics.
    Archives of general psychiatry, 1988, Volume: 45, Issue:6

    Topics: Adult; Dopamine; Female; Haloperidol; Homovanillic Acid; Humans; Male; Probability; Psychiatric Stat

1988
Plasma homovanillic acid levels and subtyping of schizophrenia.
    Psychiatry research, 1988, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Female; Haloperidol; Homovanillic Acid; Humans; Male; Middle Aged; Prognosis; Sch

1988
Effects of debrisoquin on plasma homovanillic acid concentration in schizophrenic patients.
    Psychopharmacology bulletin, 1987, Volume: 23, Issue:3

    Topics: Adult; Debrisoquin; Homovanillic Acid; Humans; Isoquinolines; Male; Schizophrenia

1987
Effects of debrisoquin and haloperidol on plasma homovanillic acid concentration in schizophrenic patients.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1987, Volume: 1, Issue:1

    Topics: Adult; Debrisoquin; Drug Therapy, Combination; Haloperidol; Homovanillic Acid; Humans; Isoquinolines

1987
Structural brain pathology in schizophrenia revisited. Prefrontal cortex pathology is inversely correlated with cerebrospinal fluid levels of homovanillic acid.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1987, Volume: 1, Issue:1

    Topics: Adult; Atrophy; Cerebral Cortex; Cerebral Ventricles; Cerebral Ventriculography; Female; Homovanilli

1987
Elevation of plasma homovanillic acid level can be detected within four hours after initiation of haloperidol treatment.
    Archives of general psychiatry, 1987, Volume: 44, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Female; Haloperidol; Homovanillic Acid; Humans; Male; Prolact

1987
Increase in human urine homovanillic acid concentration after neuroleptic treatment is the same with or without debrisoquin administration.
    Archives of general psychiatry, 1987, Volume: 44, Issue:12

    Topics: Brain; Debrisoquin; Dopamine; Haloperidol; Homovanillic Acid; Humans; Isoquinolines; Male; Schizophr

1987
Dopamine metabolism in the cerebrospinal fluid of drug-free schizophrenic patients with and without cortical atrophy.
    Archives of general psychiatry, 1986, Volume: 43, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Atrophy; Cerebral Cortex; Dopamine; Female; Homov

1986
Cerebrospinal fluid HVA, central brain atrophy, and clinical state in schizophrenia.
    Psychiatry research, 1986, Volume: 19, Issue:3

    Topics: Adult; Atrophy; Brain; Cerebral Ventricles; Chronic Disease; Female; Homovanillic Acid; Humans; Male

1986
Short-term haloperidol administration acutely elevates human plasma homovanillic acid concentration.
    Archives of general psychiatry, 1987, Volume: 44, Issue:2

    Topics: Brain; Dopamine; Haloperidol; Homovanillic Acid; Humans; Schizophrenia; Time Factors

1987
Central catecholamines, cognitive impairment, and affective state in elderly schizophrenics and controls.
    Biological psychiatry, 1987, Volume: 22, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Affect; Aged; Catecholamines; Cognition; Homovanillic Acid; Humans;

1987
Biochemical alterations produced by neuroleptics in man: studies of plasma homovanillic acid in schizophrenic patients.
    Psychopharmacology series, 1987, Volume: 3

    Topics: Adult; Female; Fluphenazine; Genetic Variation; Homovanillic Acid; Humans; Male; Schizophrenia; Time

1987
Apomorphine has no effect on plasma homovanillic acid in schizophrenic patients.
    Psychiatry research, 1985, Volume: 16, Issue:2

    Topics: Adult; Apomorphine; Haloperidol; Homovanillic Acid; Humans; Male; Middle Aged; Psychotic Disorders;

1985
Neuroendocrine aspects in monitoring of dopaminergic drugs in man.
    Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:8

    Topics: Apomorphine; Bromocriptine; Growth Hormone; Homovanillic Acid; Humans; Levodopa; Male; Metoclopramid

1985
Plasma homovanillic acid concentration and the severity of schizophrenic illness.
    Science (New York, N.Y.), 1985, Mar-29, Volume: 227, Issue:4694

    Topics: Adult; Haloperidol; Homovanillic Acid; Humans; Male; Phenylacetates; Schizophrenia

1985
Evidence for a daily rhythm of plasma HVA in normal controls but not in schizophrenic patients.
    Psychopharmacology bulletin, 1985, Volume: 21, Issue:3

    Topics: Adult; Circadian Rhythm; Female; Homovanillic Acid; Humans; Male; Phenylacetates; Schizophrenia; Tim

1985
Postmortem central catecholamines and antemortem cognitive impairment in elderly schizophrenics and controls.
    Neuropsychobiology, 1985, Volume: 14, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Brain Chemistry; Catecholamines; Cognition; Dementia; Dopamine

1985
Further studies on the mechanism of antipsychotic action: potentiation by alpha-methyltyrosine of thioridazine effects in chronic schizophrenics.
    Journal of neural transmission, 1973, Volume: 34, Issue:2

    Topics: Chronic Disease; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hyd

1973
Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Brain Diseases; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovani

1974
[Effect of clozapine on the excretion of 3-methoxy-4-hydroxy-phenylglycol, homovanillic acid and 5-hydroxy-indole acetic acid in urine and cerebrospinal fluid].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:7

    Topics: Azepines; Bipolar Disorder; Dopamine beta-Hydroxylase; Glycols; Homovanillic Acid; Humans; Hydroxyin

1974
Amphetamine psychosis: behavioral and biochemical aspects.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Adolescent; Adult; Affect; Alcoholism; Amphetamine; Brain; Cognition Disorders; Delusions; Depressio

1974
Mass fragmentometric determination of homovanillic acid in lumbar cerebrospinal fluid of schizophrenic patients during treatment with antipsychotic drugs.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Adult; Age Factors; Bipolar Disorder; Brain; Chlorpromazine; Chromatography, Gas; Deuterium; Dopamin

1974
Simultaneous quantification of homovanillic acid and 5-hydroxyindoleacetic acid in cerebrospinal fluid by mass fragmentography.
    Life sciences, 1974, Jun-16, Volume: 14, Issue:12

    Topics: Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Schizophr

1974
Dopamine-beta-hydroxylase: evidence for increased activity in sympathetic neurons during psychotic states.
    Science (New York, N.Y.), 1973, Nov-20, Volume: 182, Issue:4115

    Topics: Bipolar Disorder; Dopamine; Dopamine beta-Hydroxylase; Homovanillic Acid; Humans; Male; Methoxyhydro

1973
[Pharmacological and neurochemical effects of clozapine (Leponex): new aspects in the drug therapy of schizophrenia].
    Schweizerische medizinische Wochenschrift, 1973, Dec-01, Volume: 103, Issue:48

    Topics: Animals; Brain Stem; Caudate Nucleus; Corpus Striatum; Dibenzazepines; Dibenzoxazepines; Dopamine; E

1973
Mass fragmentographic analysis of homovanillic acid and its homoiso analogue in cerebrospinal fluid using the alpha-dideutero acid as internal standard.
    Psychopharmacologia, 1974, Mar-09, Volume: 35, Issue:4

    Topics: Deuterium; Homovanillic Acid; Humans; Isomerism; Mass Spectrometry; Methods; Phenylacetates; Schizop

1974
Central dopamine turnover in schizophrenic syndromes.
    Archives of general psychiatry, 1974, Volume: 31, Issue:1

    Topics: Affective Symptoms; Chlorpromazine; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic

1974
Antipsychotic efficacy of clozapine in correlation to changes in catecholamine metabolism in man.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Bipolar Disorder; Carbon Radioisotopes; Catecholamines; Chromatography, Gas; Dibenzazepines; Dopamin

1974