homovanillic acid has been researched along with Rett Syndrome in 5 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The metabolites of dopamine (homovanillic acid-HVA), noradrenaline (4-hydroxy-3-methoxy-phenylglycol-HMPG), and serotonin (5-hydroxyindoleacetic acid-5-HIAA) were measured in cerebrospinal fluid (CSF) from 38 patients and urine from 36 patients with typical Rett syndrome (RS) and compared with controls of similar age." | 3.68 | CSF and urine biogenic amine metabolites in Rett syndrome. ( Hagberg, B; Holmberg, B; Lekman, A; Percy, A; Svennerholm, L; Witt-Engerström, I, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Humphreys, P | 1 |
| Barrowman, N | 1 |
| Temudo, T | 1 |
| Rios, M | 1 |
| Prior, C | 1 |
| Carrilho, I | 1 |
| Santos, M | 1 |
| Maciel, P | 1 |
| Sequeiros, J | 1 |
| Fonseca, M | 1 |
| Monteiro, J | 1 |
| Cabral, P | 1 |
| Vieira, JP | 1 |
| Ormazabal, A | 1 |
| Artuch, R | 1 |
| Nielsen, JB | 2 |
| Bertelsen, A | 1 |
| Lou, HC | 2 |
| Lekman, A | 1 |
| Witt-Engerström, I | 1 |
| Holmberg, B | 1 |
| Percy, A | 1 |
| Svennerholm, L | 1 |
| Hagberg, B | 1 |
| Andresen, J | 1 |
2 trials available for homovanillic acid and Rett Syndrome
| Article | Year |
|---|---|
Evaluation of CSF neurotransmitters and folate in 25 patients with Rett disorder and effects of treatment.
Topics: Administration, Oral; Child; Child, Preschool; DNA Mutational Analysis; Female; Fluoxetine; Folic Ac | 2009 |
Biochemical and clinical effects of tyrosine and tryptophan in the Rett syndrome.
Topics: Adolescent; Child; Dopamine; Double-Blind Method; Female; Homovanillic Acid; Humans; Hydroxyindoleac | 1990 |
3 other studies available for homovanillic acid and Rett Syndrome
| Article | Year |
|---|---|
The Incidence and Evolution of Parkinsonian Rigidity in Rett Syndrome: A Pilot Study.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Indoles; Male; Methyl | 2016 |
Low CSF HVA levels in the Rett syndrome: a reflection of restricted synapse formation?
Topics: Adolescent; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Ma | 1992 |
CSF and urine biogenic amine metabolites in Rett syndrome.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Creatinine; Dopamine; Female; Glycols; Homo | 1990 |