homovanillic acid has been researched along with Pain in 16 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to investigate the discriminative power of a series of variables (including determination of depressive symptomatology by means of a visual analogue scale, determination of personality traits by means of the Karolinska Scales of Personality, determination of monoamine metabolites in CSF, platelet MAO activities, serum cortisol before and after dexamethasone suppression and urinary melatonin) in differentiating chronic pain patients from healthy subjects, and patients with idiopathic pain syndromes from patients with neurogenic pain syndromes." | 7.67 | Discrimination of idiopathic pain syndromes from neurogenic pain syndromes and healthy volunteers by means of clinical rating, personality traits, monoamine metabolites in CSF, serum cortisol, platelet MAO and urinary melatonin. ( Almay, BG; Häggendal, J; Johansson, F; Oreland, L; von Knorring, L; Wetterberg, L, 1986) |
| "A quantitative method for measuring the efficiency of pungent agents of capsaicin-type by the pain reaction elicited on the eye of rats is described." | 7.65 | Sensory effects of capsaicin congeners I. Relationship between chemical structure and pain-producing potency of pungent agents. ( Jancsó-Gábor, A; Szolcsányi, J, 1975) |
| "The aim of the present study was to investigate the discriminative power of a series of variables (including determination of depressive symptomatology by means of a visual analogue scale, determination of personality traits by means of the Karolinska Scales of Personality, determination of monoamine metabolites in CSF, platelet MAO activities, serum cortisol before and after dexamethasone suppression and urinary melatonin) in differentiating chronic pain patients from healthy subjects, and patients with idiopathic pain syndromes from patients with neurogenic pain syndromes." | 3.67 | Discrimination of idiopathic pain syndromes from neurogenic pain syndromes and healthy volunteers by means of clinical rating, personality traits, monoamine metabolites in CSF, serum cortisol, platelet MAO and urinary melatonin. ( Almay, BG; Häggendal, J; Johansson, F; Oreland, L; von Knorring, L; Wetterberg, L, 1986) |
| "Patients with idiopathic pain syndromes were compared with healthy volunteers and with patients suffering from chronic pain syndromes of neurogenic origin, with respect to the concentrations of the metabolites 5-hydroxy-indole-acetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF)." | 3.67 | 5-HIAA and HVA in CSF in patients with idiopathic pain disorders. ( Almay, BG; Häggendal, J; Oreland, L; von Knorring, L, 1987) |
| "The characteristic insensitivity of sensory nerve endings to chemically induced pain brought about by capsaicin could be reproduced on the rat's eye by pungent vanillylamides, homovanilloyl-alkylamides and piperine, while homovanilloyl-cycloalkylamides, -azacycloalkylamides, - alkylesters, -alkyl-homovanillylamides, undecenoyl-3-aminopropranololand zingerone were practically ineffective in this respect." | 3.65 | Sensory effects of capsaicin congeners. Part II: Importance of chemical structure and pungency in desensitizing activity of capsaicin-type compounds. ( Jancsó-Gábor, A; Szolcsányi, J, 1976) |
| "A quantitative method for measuring the efficiency of pungent agents of capsaicin-type by the pain reaction elicited on the eye of rats is described." | 3.65 | Sensory effects of capsaicin congeners I. Relationship between chemical structure and pain-producing potency of pungent agents. ( Jancsó-Gábor, A; Szolcsányi, J, 1975) |
| "In headache sufferers, Ac-beta-EP levels were always detectable and their mean value was significantly higher than that of healthy subjects (11." | 1.28 | Evidence of alpha-N-acetyl beta-endorphin in human cerebrospinal fluid. ( Facchinetti, F; Genazzani, AR; Martignoni, E; Nappi, G; Pagani, I; Sances, G, 1992) |
| "Among Parkinson's disease (PD) patients complaining of pain, 10 with pain not associated with a motor fluctuation or L-dopa therapy were evaluated." | 1.28 | The threshold of pain and neurotransmitter's change on pain in Parkinson's disease. ( Matsushima, E; Nishikawa, S; Sano, K; Takahashi, K; Takao, T; Urakami, K, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Almay, BG | 4 |
| Johansson, F | 4 |
| von Knorring, L | 5 |
| Sedvall, G | 1 |
| Terenius, L | 2 |
| Jhamandas, K | 1 |
| Yaksh, TL | 1 |
| Harty, G | 1 |
| Szolcsanyi, J | 3 |
| Go, VL | 1 |
| McCann, UD | 1 |
| Ridenour, A | 1 |
| Shaham, Y | 1 |
| Ricaurte, GA | 1 |
| Kääriäinen, I | 1 |
| Ahtee, L | 1 |
| Jancsó-Gábor, A | 2 |
| Facchinetti, F | 1 |
| Sances, G | 1 |
| Martignoni, E | 1 |
| Pagani, I | 1 |
| Nappi, G | 1 |
| Genazzani, AR | 1 |
| Houvenagel, E | 1 |
| Forzy, G | 1 |
| Leloire, O | 1 |
| Gallois, P | 1 |
| Hary, S | 1 |
| Hautecoeur, P | 1 |
| Convain, L | 1 |
| Henniaux, M | 1 |
| Vincent, G | 1 |
| Dhondt, JL | 1 |
| Urakami, K | 1 |
| Takahashi, K | 1 |
| Matsushima, E | 1 |
| Sano, K | 1 |
| Nishikawa, S | 1 |
| Takao, T | 1 |
| Boutelle, MG | 1 |
| Zetterström, T | 1 |
| Pei, Q | 1 |
| Svensson, L | 1 |
| Fillenz, M | 1 |
| Sakurada, T | 1 |
| del Ser, T | 1 |
| Franch, O | 1 |
| Portera, A | 1 |
| Muradas, V | 1 |
| Yebenes, JG | 1 |
| Oreland, L | 3 |
| Häggendal, J | 3 |
| Magnusson, T | 1 |
| Almay, B | 1 |
| Wetterberg, L | 1 |
| France, RD | 1 |
| Urban, BJ | 1 |
| Pelton, S | 1 |
| Kilts, CD | 1 |
| Hong, JS | 1 |
| Nemeroff, CB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hypoalgesic Effects of Specific vs Non-specific Cervical Manipulation in Healthy Subjects[NCT03541538] | 21 participants (Actual) | Interventional | 2018-06-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for homovanillic acid and Pain
| Article | Year |
|---|---|
Serotonin neurotoxicity after (+/-)3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Analysis of Variance; Female; Homovanillic Acid; Humans; Hydro | 1994 |
15 other studies available for homovanillic acid and Pain
| Article | Year |
|---|---|
Relationships between CSF levels of endorphins and monoamine metabolites in chronic pain patients.
Topics: Adult; Aged; Biogenic Amines; Chronic Disease; Endorphins; Female; Homovanillic Acid; Humans; Hydrox | 1980 |
Action of intrathecal capsaicin and its structural analogues on the content and release of spinal substance P: selectivity of action and relationship to analgesia.
Topics: Animals; Capsaicin; Cholecystokinin; Homovanillic Acid; Injections, Spinal; Male; Pain; Phenylacetat | 1984 |
Effect of narcotic analgesics on the striatal homovanillic acid content in mice; relation to antinociceptive effect.
Topics: Analgesics, Opioid; Animals; Body Temperature; Corpus Striatum; Cyclazocine; Haloperidol; Homovanill | 1976 |
Sensory effects of capsaicin congeners. Part II: Importance of chemical structure and pungency in desensitizing activity of capsaicin-type compounds.
Topics: Animals; Capsaicin; Condiments; Fatty Acids, Unsaturated; Homovanillic Acid; Pain; Rats; Sensory Rec | 1976 |
Sensory effects of capsaicin congeners I. Relationship between chemical structure and pain-producing potency of pungent agents.
Topics: Animals; Butanones; Capsaicin; Condiments; Dose-Response Relationship, Drug; Fatty Acids, Unsaturate | 1975 |
Evidence of alpha-N-acetyl beta-endorphin in human cerebrospinal fluid.
Topics: Adult; Aged; beta-Endorphin; Chromatography, High Pressure Liquid; Chronic Disease; Female; Headache | 1992 |
[Cerebrospinal fluid monoamines in primary fibromyalgia].
Topics: Adult; Chronic Disease; Dopamine; Female; Fibromyalgia; Homovanillic Acid; Humans; Hydroxyindoleacet | 1990 |
The threshold of pain and neurotransmitter's change on pain in Parkinson's disease.
Topics: Aged; beta-Endorphin; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydr | 1990 |
In vivo neurochemical effects of tail pinch.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Brain Chemistry; Chromatography, High Pressu | 1990 |
Long-term high frequency transcutaneous electrical nerve stimulation (hi-TNS) in chronic pain. Clinical response and effects on CSF-endorphins, monoamine metabolites, substance P-like immunoreactivity (SPLI) and pain measures.
Topics: Adult; Aged; Chronic Disease; Electric Stimulation Therapy; Endorphins; Female; Follow-Up Studies; G | 1985 |
Neurotransmitter changes in cerebrospinal fluid in the Spanish toxic oil syndrome: human clinical findings and experimental results in mice.
Topics: Anilides; Animals; Brain Chemistry; Brassica; Catecholamines; Disease Models, Animal; Foodborne Dise | 1986 |
Relationship between platelet MAO activity and concentrations of 5-HIAA and HVA in cerebrospinal fluid in chronic pain patients.
Topics: Age Factors; Blood Platelets; Body Height; Chronic Disease; Female; Homovanillic Acid; Humans; Hydro | 1986 |
Discrimination of idiopathic pain syndromes from neurogenic pain syndromes and healthy volunteers by means of clinical rating, personality traits, monoamine metabolites in CSF, serum cortisol, platelet MAO and urinary melatonin.
Topics: Adult; Chronic Disease; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydrocortisone; Hydr | 1986 |
5-HIAA and HVA in CSF in patients with idiopathic pain disorders.
Topics: Adult; Age Factors; Aged; Body Weight; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydro | 1987 |
CSF monoamine metabolites in chronic pain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Back Pain; Biogenic Amines; Chronic Disease; Depressive | 1987 |