Page last updated: 2024-10-21

homovanillic acid and Obesity

homovanillic acid has been researched along with Obesity in 11 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"We examined whether reductions in body fat stores and insulin resistance in Syrian hamsters induced by bromocriptine are associated with reductions in daily norepinephrine (NE) and serotonin activities as indicated by their extracellular metabolite levels in the ventromedial hypothalamus (VMH)."7.70Bromocriptine reduces obesity, glucose intolerance and extracellular monoamine metabolite levels in the ventromedial hypothalamus of Syrian hamsters. ( Cincotta, AH; Luo, S; Meier, AH, 1998)
"When the hypothalamic ventromedial nucleus and arcuate nucleus were destroyed in rats by treatment with monosodium glutamate in the neonatal stage, increase in the Lee index (body weight 1/3/body length) and in retroperitoneal fat as well as decreases in spontaneous motor activity, food consumption and growth hormone secretion function associated with hypothalamic low body length obesity (monosodium glutamate-treated obesity; MSG-OB) were observed as these rats grew."7.70Effects of chronic administration of sibutramine on body weight, food intake and motor activity in neonatally monosodium glutamate-treated obese female rats: relationship of antiobesity effect with monoamines. ( Gomita, Y; Nakagawa, T; Ohyama, T; Okamura, H; Ukai, K, 2000)
" high protein (HP) breakfast leads to alterations in food cravings and plasma homovanillic acid (HVA), which is an index of central dopamine production, in overweight/obese 'breakfast skipping' late-adolescent young women."5.19A randomized crossover, pilot study examining the effects of a normal protein vs. high protein breakfast on food cravings and reward signals in overweight/obese "breakfast skipping", late-adolescent girls. ( Hoertel, HA; Leidy, HJ; Will, MJ, 2014)
"We examined whether reductions in body fat stores and insulin resistance in Syrian hamsters induced by bromocriptine are associated with reductions in daily norepinephrine (NE) and serotonin activities as indicated by their extracellular metabolite levels in the ventromedial hypothalamus (VMH)."3.70Bromocriptine reduces obesity, glucose intolerance and extracellular monoamine metabolite levels in the ventromedial hypothalamus of Syrian hamsters. ( Cincotta, AH; Luo, S; Meier, AH, 1998)
"When the hypothalamic ventromedial nucleus and arcuate nucleus were destroyed in rats by treatment with monosodium glutamate in the neonatal stage, increase in the Lee index (body weight 1/3/body length) and in retroperitoneal fat as well as decreases in spontaneous motor activity, food consumption and growth hormone secretion function associated with hypothalamic low body length obesity (monosodium glutamate-treated obesity; MSG-OB) were observed as these rats grew."3.70Effects of chronic administration of sibutramine on body weight, food intake and motor activity in neonatally monosodium glutamate-treated obese female rats: relationship of antiobesity effect with monoamines. ( Gomita, Y; Nakagawa, T; Ohyama, T; Okamura, H; Ukai, K, 2000)
"The effect of obesity and tyrosine (tyr) supplements on catecholamine metabolism in 12 normal weight and nine obese adult women was studied."3.66Obesity and precursor availability affect urinary catecholamine metabolite production in women. ( Anderson, GH; Johnston, JL; Warsh, JJ, 1983)
"Severe obesity is a major problem in patients suffering from craniopharyngioma (CP), a benign tumor located in pituitary and hypothalamic regions."1.34Reduced sympathetic metabolites in urine of obese patients with craniopharyngioma. ( Gebhardt, U; Hunneman, DH; Müller, HL; Reinehr, T; Roth, CL; Stoffel-Wagner, B, 2007)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoertel, HA1
Will, MJ1
Leidy, HJ1
Roth, CL1
Hunneman, DH1
Gebhardt, U1
Stoffel-Wagner, B1
Reinehr, T1
Müller, HL1
Cramer, H1
Warter, JM1
Renaud, B1
Krieger, J1
Marescaux, CH1
Hammers, R1
Johnston, JL1
Warsh, JJ1
Anderson, GH1
Strömbom, U1
Krotkiewski, M1
Blennow, K1
Månsson, JE2
Ekman, R2
Björntorp, P1
Luo, S1
Meier, AH1
Cincotta, AH1
Akefeldt, A1
Gillberg, C1
Nakagawa, T1
Ukai, K1
Ohyama, T1
Gomita, Y1
Okamura, H1
Kishi, E1
Takahashi, A1
Ishimaru, H1
Ikarashi, Y1
Maruyama, Y1
Dawson, R1
Callahan, MF1
Annau, Z1
Orosco, M1
Trouvin, JH1
Cohen, Y1
Jacquot, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of a High Protein Breakfast on Appetite and Sleep in Young Adults[NCT03031132]13 participants (Actual)Interventional2016-06-30Suspended (stopped due to Transferring study to another University)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for homovanillic acid and Obesity

ArticleYear
A randomized crossover, pilot study examining the effects of a normal protein vs. high protein breakfast on food cravings and reward signals in overweight/obese "breakfast skipping", late-adolescent girls.
    Nutrition journal, 2014, Aug-06, Volume: 13

    Topics: Adolescent; Body Mass Index; Breakfast; Craving; Cross-Over Studies; Diet; Dietary Proteins; Energy

2014

Other Studies

10 other studies available for homovanillic acid and Obesity

ArticleYear
Reduced sympathetic metabolites in urine of obese patients with craniopharyngioma.
    Pediatric research, 2007, Volume: 61, Issue:4

    Topics: Adolescent; Adult; Craniopharyngioma; Dopamine; Epinephrine; Female; Homovanillic Acid; Humans; Male

2007
Cerebrospinal fluid adenosine 3',5'-monophosphate, 5-hydroxyindoleacetic acid and homovanillic acid in patients with sleep apnoea syndrome.
    Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:12

    Topics: Cyclic AMP; Disorders of Excessive Somnolence; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti

1981
Obesity and precursor availability affect urinary catecholamine metabolite production in women.
    The American journal of clinical nutrition, 1983, Volume: 38, Issue:3

    Topics: Adult; Amino Acids; Body Composition; Catecholamines; Circadian Rhythm; Dietary Proteins; Dopamine;

1983
The concentrations of monoamine metabolites and neuropeptides in the cerebrospinal fluid of obese women with different body fat distribution.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1996, Volume: 20, Issue:4

    Topics: Adipose Tissue; Adult; beta-Endorphin; Biogenic Monoamines; Body Composition; Body Constitution; Bod

1996
Bromocriptine reduces obesity, glucose intolerance and extracellular monoamine metabolite levels in the ventromedial hypothalamus of Syrian hamsters.
    Neuroendocrinology, 1998, Volume: 68, Issue:1

    Topics: Adipose Tissue; Animals; Biogenic Monoamines; Body Composition; Bromocriptine; Chromatography, High

1998
Cerebrospinal fluid monoamines in Prader-Willi syndrome.
    Biological psychiatry, 1998, Dec-15, Volume: 44, Issue:12

    Topics: Adolescent; Adult; Age Factors; Autistic Disorder; Birth Weight; Body Mass Index; Child; Child, Pres

1998
Effects of chronic administration of sibutramine on body weight, food intake and motor activity in neonatally monosodium glutamate-treated obese female rats: relationship of antiobesity effect with monoamines.
    Experimental animals, 2000, Volume: 49, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adipose Tissue; Animals; Animals, Newborn; Appetite Depressants; Arc

2000
Development of obesity and neurochemical backing in aurothioglucose-treated mice.
    Autonomic neuroscience : basic & clinical, 2001, Sep-17, Volume: 92, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Antineoplastic Combined Chemotherapy Protoco

2001
Hypothalamic monoamine metabolism in mice: evaluation of drug challenges and neurotoxic insult.
    Pharmacology, 1986, Volume: 32, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Animals, Newborn; Dopamine; Female; G

1986
Ontogeny of brain monoamines in lean and obese female Zucker rats.
    Physiology & behavior, 1986, Volume: 36, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Biogenic Amines; Brain Chemistry; Dopamine; Fe

1986