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homovanillic acid and Neuroleptic Malignant Syndrome

homovanillic acid has been researched along with Neuroleptic Malignant Syndrome in 10 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research Excerpts

ExcerptRelevanceReference
"Homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) levels in the cerebrospinal fluid (CSF) were determined twice in nine cases of neuroleptic malignant syndrome (NMS) during the active phase."7.68Does dantrolene influence central dopamine and serotonin metabolism in the neuroleptic malignant syndrome? A retrospective study. ( Ishiguro, T; Nisijima, K, 1993)
"Homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) levels in the cerebrospinal fluid (CSF) were determined twice in nine cases of neuroleptic malignant syndrome (NMS) during the active phase."3.68Does dantrolene influence central dopamine and serotonin metabolism in the neuroleptic malignant syndrome? A retrospective study. ( Ishiguro, T; Nisijima, K, 1993)
"In 8 cases of typical neuroleptic malignant syndrome (NMS), homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA), noradrenaline (NA), and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) levels in the cerebrospinal fluid (CSF) were assayed during both the active phase of NMS and after recovery."3.68Neuroleptic malignant syndrome: a study of CSF monoamine metabolism. ( Ishiguro, T; Nisijima, K, 1990)
"In nine typical cases and five mild cases of neuroleptic malignant syndrome (NMS), homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and noradrenaline (NA) and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) levels in the cerebrospinal fluid (CSF) were assayed both during the active phase of NMS and after recovery."3.67[Clinical course and CSF monoamine metabolism in neuroleptic malignant syndrome--a study of nine typical cases and five mild cases]. ( Ishiguro, T; Nishijima, K, 1989)
"To determine susceptibility to neuroleptic malignant syndrome (NMS) in patients with PD in relation to central monoamine metabolism."1.30Susceptibility to neuroleptic malignant syndrome in Parkinson's disease. ( Hamamoto, M; Katayama, Y; Miyazaki, T; Nagayama, H; Nito, C; Otsubo, K; Terashi, A; Ueda, M, 1999)
"A 79-year-old male suffering from Shy-Drager syndrome was treated with a daily dosage of 300 mg of L-threo-3,4-dihydroxyphenylserine (L-DOPS)."1.29[Monoamine imbalance of the central nervous system in a case of Shy-Drager syndrome with recurrent attacks of a neuroleptic malignant syndrome]. ( Hamamoto, M; Miyazaki, T; Otsubo, K; Terashi, A; Ueda, M, 1996)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's7 (70.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nisijima, K3
Ishiguro, T4
Oyafuso, K1
Shimada, T1
Hosino, H1
Ueda, M3
Hamamoto, M3
Otsubo, K2
Miyazaki, T2
Terashi, A2
Nagayama, H2
Nito, C1
Katayama, Y2
Okubo, S1
Amemiya, S1
Komatsu, H1
Nishimura, A1
Okano, S1
Miyanomae, Y1
Takeuchi, Y1
Sawada, T1
Goekoop, JG1
Knoppert-van der Klein, EA1
Nishijima, K1
Verhoeven, WM1
Elderson, A1
Westenberg, HG1

Reviews

1 review available for homovanillic acid and Neuroleptic Malignant Syndrome

ArticleYear
[Current developments related to the neuroleptic malignant syndrome].
    Nederlands tijdschrift voor geneeskunde, 1990, Feb-24, Volume: 134, Issue:8

    Topics: Calcium; Depressive Disorder; Fever; Homovanillic Acid; Humans; Muscle Contraction; Neuroleptic Mali

1990

Other Studies

9 other studies available for homovanillic acid and Neuroleptic Malignant Syndrome

ArticleYear
Does dantrolene influence central dopamine and serotonin metabolism in the neuroleptic malignant syndrome? A retrospective study.
    Biological psychiatry, 1993, Jan-01, Volume: 33, Issue:1

    Topics: Adult; Dantrolene; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Midd

1993
Cerebrospinal fluid monoamine metabolism in a case of neuroleptic malignant syndrome improved by electroconvulsive therapy.
    Biological psychiatry, 1996, Mar-01, Volume: 39, Issue:5

    Topics: Antidepressive Agents; Antipsychotic Agents; Depressive Disorder; Electroconvulsive Therapy; Female;

1996
[Monoamine imbalance of the central nervous system in a case of Shy-Drager syndrome with recurrent attacks of a neuroleptic malignant syndrome].
    Rinsho shinkeigaku = Clinical neurology, 1996, Volume: 36, Issue:5

    Topics: Aged; Homovanillic Acid; Humans; Male; Methoxyhydroxyphenylglycol; Neuroleptic Malignant Syndrome; S

1996
Susceptibility to neuroleptic malignant syndrome in Parkinson's disease.
    Neurology, 1999, Mar-10, Volume: 52, Issue:4

    Topics: Aged; Aged, 80 and over; Disease Susceptibility; Female; Homovanillic Acid; Humans; Hydroxyindoleace

1999
Biochemical alterations during medication withdrawal in Parkinson's disease with and without neuroleptic malignant-like syndrome.
    Journal of neurology, neurosurgery, and psychiatry, 2001, Volume: 71, Issue:1

    Topics: Aged; Analysis of Variance; Female; Homovanillic Acid; Humans; Male; Neuroleptic Malignant Syndrome;

2001
Neuroleptic malignant syndrome-like state in a patient with Down syndrome and basal ganglia calcification.
    Brain & development, 1992, Volume: 14, Issue:6

    Topics: Adolescent; Basal Ganglia Diseases; Calcinosis; Down Syndrome; Homovanillic Acid; Humans; Hydroxyind

1992
Neuroleptic malignant syndrome: a study of CSF monoamine metabolism.
    Biological psychiatry, 1990, Feb-01, Volume: 27, Issue:3

    Topics: Adult; Biogenic Monoamines; Bipolar Disorder; Depressive Disorder; Female; Homovanillic Acid; Humans

1990
[Clinical course and CSF monoamine metabolism in neuroleptic malignant syndrome--a study of nine typical cases and five mild cases].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1989, Volume: 91, Issue:6

    Topics: Adult; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphe

1989
Neuroleptic malignant syndrome: successful treatment with bromocriptine.
    Biological psychiatry, 1985, Volume: 20, Issue:6

    Topics: Adolescent; Basal Ganglia Diseases; Bromocriptine; Creatine Kinase; Haloperidol; Homovanillic Acid;

1985