homovanillic acid has been researched along with Nervous System Diseases in 38 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we explored the relationship between aggressiveness (as measured by the Overt Aggression Scale), cognitive performance (as measured by the Mini Mental State Examination), and biochemical markers of dopamine neurotransmission (homovanillic acid, HVA) and nitric oxide synthesis (nitrite plus nitrate, NO(x)) in cerebrospinal fluid from 70 patients with acute brain disorders, mainly brain infections." | 3.76 | Imbalance between nitric oxide and dopamine may underly aggression in acute neurological patients. ( Abundes-Corona, A; Montes, S; Nente, F; Perez-Neri, I; Ramirez-Abascal, M; Ramírez-Bermudez, J; Rios, C; Soto-Hernandez, JL, 2010) |
| "Maturation of monoamine neuronal systems was studied by measuring cerebrospinal fluid metabolites of dopamine (homovanillic acid) and serotonin (5-hydroxyindoleacetic acid) in 38 children with epilepsy and other neurological disorders, to whom probenecid had previously been administered." | 3.66 | Ontogeny of dopamine and serotonin metabolites in the cerebrospinal fluid of children with neurological disorders. ( Bowers, MB; Cohen, DJ; Leckman, JF; Shaywitz, BA; Young, JG, 1980) |
| "A prospective clinical and biochemical study on the effects of treatment with haloperidol has been performed in seven patients with Tourette syndrome." | 3.66 | Dopaminergic dsyfunction in Tourette syndrome. ( Butler, IJ; Coyle, JT; Seifert, WE; Singer, HS; Tune, LE, 1982) |
| "Sixteen patients with chronic congestive heart failure (CHF) and 6 patients with pure autonomic failure (PAF) were also studied to investigate possible effects of sympathetic nervous system overactivity and underactivity on peripheral HVA production and plasma HVA concentration." | 1.29 | Regional homovanillic acid production in humans. ( Eisenhofer, G; Esler, MD; Jennings, GL; Lambert, GW, 1993) |
| " Although not statistically significant, the VMA excretion was also noted to be moderately elevated; however, it is recognized that the present study was unable to establish a highly significant dose-response relationship between lead exposure and HVA excretion, as has been reported earlier in lead-poisoned children." | 1.28 | Neurochemical effect of lead exposure: a study on catecholamine metabolism. ( Chia, KS; Koh, D; Ong, CN; Saijoh, K, 1989) |
| "The striatal concentration of dopamine (DA), norepinephrine (NE), and homovanillic acid (HVA) was assessed in adult male rabbits exposed to styrene vapours or dosed with mandelic acid (MA), phenylglyoxylic acid (PGA) and phenylglycine (PG)." | 1.27 | Styrene metabolism and striatal dopamine depletion in rabbits. ( Falzoi, M; Franchini, I; Lucertini, S; Mutti, A; Romanelli, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (57.89) | 18.7374 |
| 1990's | 8 (21.05) | 18.2507 |
| 2000's | 2 (5.26) | 29.6817 |
| 2010's | 4 (10.53) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Vilanakis, E | 3 |
| Papakonstantinou, E | 3 |
| Paramera, E | 3 |
| Argyri, I | 3 |
| Drakou, E | 3 |
| Kokkinou, E | 3 |
| Zouvelou, V | 3 |
| Outsika, C | 3 |
| Pons, R | 4 |
| Grabska-Kobylecka, I | 1 |
| Kaczmarek-Bak, J | 1 |
| Figlus, M | 1 |
| Prymont-Przyminska, A | 1 |
| Zwolinska, A | 1 |
| Sarniak, A | 1 |
| Wlodarczyk, A | 1 |
| Glabinski, A | 1 |
| Nowak, D | 1 |
| Molero-Luis, M | 1 |
| Serrano, M | 2 |
| Ormazábal, A | 2 |
| Pérez-Dueñas, B | 2 |
| García-Cazorla, A | 2 |
| Artuch, R | 1 |
| Kurian, MA | 1 |
| Ramírez-Bermudez, J | 1 |
| Perez-Neri, I | 1 |
| Montes, S | 1 |
| Ramirez-Abascal, M | 1 |
| Nente, F | 1 |
| Abundes-Corona, A | 1 |
| Soto-Hernandez, JL | 1 |
| Rios, C | 1 |
| Shi, X | 1 |
| Zhang, L | 1 |
| Fu, S | 1 |
| Li, N | 1 |
| González, V | 1 |
| Pineda, M | 1 |
| Fernández-Alvarez, E | 1 |
| Campistol, JM | 1 |
| Artuch, RM | 1 |
| Bottiglieri, T | 1 |
| Lim, CK | 1 |
| Peters, TJ | 1 |
| Shaywitz, BA | 1 |
| Cohen, DJ | 1 |
| Leckman, JF | 1 |
| Young, JG | 1 |
| Bowers, MB | 1 |
| Van Woert, MH | 1 |
| Magnussen, I | 1 |
| Lowe, YH | 1 |
| Hwang, EC | 1 |
| Singer, HS | 1 |
| Butler, IJ | 1 |
| Tune, LE | 1 |
| Seifert, WE | 1 |
| Coyle, JT | 1 |
| Gagnieu, MC | 1 |
| Menouni-Foray, V | 1 |
| Guardiola, P | 1 |
| Quincy, C | 1 |
| Renaud, B | 1 |
| Hornykiewicz, O | 1 |
| Shekim, WO | 1 |
| Daniel, AE | 1 |
| Koresko, RL | 1 |
| Dekirmenjian, H | 1 |
| Candito, M | 1 |
| Nagatsu, T | 1 |
| Chambon, P | 1 |
| Chatel, M | 1 |
| Vizuete, ML | 1 |
| Steffen, V | 1 |
| Machado, A | 1 |
| Cano, J | 1 |
| Oishi, T | 1 |
| Hasegawa, E | 1 |
| Murai, Y | 1 |
| Lambert, GW | 1 |
| Eisenhofer, G | 1 |
| Jennings, GL | 1 |
| Esler, MD | 1 |
| Wakata, N | 1 |
| Araki, Y | 1 |
| Sugimoto, H | 1 |
| Iguchi, H | 1 |
| Kinoshita, M | 1 |
| Moskowitz, MA | 2 |
| Wurtman, RJ | 2 |
| Askenasy, JJ | 1 |
| Samuel, D | 1 |
| Streifler, M | 1 |
| Christie, DL | 1 |
| Knauss, TA | 1 |
| Zeman, J | 1 |
| Böswart, J | 1 |
| Davis, BA | 1 |
| Durden, DA | 1 |
| O'Reilly, RL | 1 |
| Naudin, B | 1 |
| Saligaut, C | 1 |
| Costentin, J | 1 |
| Carr, LA | 1 |
| Rowell, PP | 1 |
| Ichikawa, N | 1 |
| Fuller, RW | 1 |
| Hemrick-Luecke, SK | 1 |
| Scheinin, M | 1 |
| Ong, CN | 1 |
| Chia, KS | 1 |
| Koh, D | 1 |
| Saijoh, K | 1 |
| Hippius, H | 1 |
| Ackenheil, M | 1 |
| Müller-Spahn, F | 1 |
| Mutti, A | 1 |
| Romanelli, A | 1 |
| Falzoi, M | 1 |
| Lucertini, S | 1 |
| Franchini, I | 1 |
| Corsini, GU | 1 |
| Pintus, S | 1 |
| Chiueh, CC | 1 |
| Weiss, JF | 1 |
| Kopin, IJ | 1 |
| Youngster, SK | 1 |
| Sonsalla, PK | 1 |
| Heikkila, RE | 2 |
| Curzon, G | 1 |
| Mrochek, JE | 1 |
| Dinsmore, SR | 1 |
| Ohrt, DW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00004325] | 200 participants | Observational | 1988-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for homovanillic acid and Nervous System Diseases
| Article | Year |
|---|---|
Catecholamines and neurologic diseases (second of two parts).
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Brain Diseases; Catecholamines; Cereb | 1975 |
Monoamine metabolites in human cerebrospinal fluid: indicators of neuronal activity?
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Biogenic Amines; Brain Diseases; Glycols; Homo | 1985 |
Neuroendocrinological and biochemical effects of chronic neuroleptic treatment.
Topics: Adult; Antipsychotic Agents; Apomorphine; beta-Endorphin; Drug Tolerance; Endocrine System Diseases; | 1985 |
35 other studies available for homovanillic acid and Nervous System Diseases
| Article | Year |
|---|---|
Cerebrospinal Fluid Concentrations of Neurotransmitters in a Greek Pediatric Reference Population.
Topics: Biogenic Amines; Child; Greece; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Nervous | 2023 |
Cerebrospinal Fluid Concentrations of Neurotransmitters in a Greek Pediatric Reference Population.
Topics: Biogenic Amines; Child; Greece; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Nervous | 2023 |
Cerebrospinal Fluid Concentrations of Neurotransmitters in a Greek Pediatric Reference Population.
Topics: Biogenic Amines; Child; Greece; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Nervous | 2023 |
Cerebrospinal Fluid Concentrations of Neurotransmitters in a Greek Pediatric Reference Population.
Topics: Biogenic Amines; Child; Greece; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Nervous | 2023 |
The Presence of Caffeic Acid in Cerebrospinal Fluid: Evidence That Dietary Polyphenols Can Cross the Blood-Brain Barrier in Humans.
Topics: Adult; Blood-Brain Barrier; Caffeic Acids; Chromatography, High Pressure Liquid; Diet, Western; Fema | 2020 |
Homovanillic acid in cerebrospinal fluid of 1388 children with neurological disorders.
Topics: Adolescent; Algorithms; Asphyxia Neonatorum; Brain; Central Nervous System Infections; Child; Child, | 2013 |
What is the role of dopamine in childhood neurological disorders?
Topics: Female; Homovanillic Acid; Humans; Male; Nervous System Diseases | 2013 |
Imbalance between nitric oxide and dopamine may underly aggression in acute neurological patients.
Topics: Acute Disease; Adult; Aggression; Cognition; Dopamine; Female; Homovanillic Acid; Humans; Male; Nerv | 2010 |
Co-involvement of psychological and neurological abnormalities in infertility with polycystic ovarian syndrome.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anxiety; Checklist; Depression; Diagnostic Self Evaluation; Dopamine | 2011 |
Secondary abnormalities of neurotransmitters in infants with neurological disorders.
Topics: 5-Hydroxytryptophan; Atrophy; Brain; Electroencephalography; Epilepsy; Female; Homovanillic Acid; Hu | 2007 |
Isocratic analysis of 3-methoxy-4-hydroxyphenyl glycol, 5-hydroxyindole-3-acetic acid and 4-hydroxy-3-methoxyphenylacetic acid in cerebrospinal fluid by high-performance liquid chromatography with amperometric detection.
Topics: Buffers; Chromatography, High Pressure Liquid; Depressive Disorder; Glycols; Homovanillic Acid; Huma | 1984 |
Ontogeny of dopamine and serotonin metabolites in the cerebrospinal fluid of children with neurological disorders.
Topics: Adolescent; Child; Child, Preschool; Dopamine; Epilepsy; Female; Homovanillic Acid; Humans; Hydroxyi | 1980 |
Study of serotonin in neuropsychiatric disorders.
Topics: 5-Hydroxytryptophan; Carbidopa; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetic | 1982 |
Dopaminergic dsyfunction in Tourette syndrome.
Topics: Adolescent; Dopamine; Female; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male | 1982 |
Liquid chromatographic determination of homovanillic acid, 5-hydroxyindoleacetic acid and probenecid levels in human cerebrospinal fluid during probenecid test.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Electrochemistry; Homovanillic Acid; Humans | 1984 |
Imbalance of brain monoamines and clinical disorders.
Topics: Biogenic Amines; Brain; Depressive Disorder; Dopamine; Homovanillic Acid; Humans; Nervous System Dis | 1982 |
Catecholamine metabolites in congenital sensory neuropathy with anhydrosis.
Topics: Body Temperature Regulation; Catecholamines; Child; Homovanillic Acid; Humans; Hyperkinesis; Hypesth | 1980 |
High-performance liquid chromatographic measurement of cerebrospinal fluid tetrahydrobiopterin, neopterin, homovanillic acid and 5-hydroxindoleacetic acid in neurological diseases.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aged, 80 and over; Biopterins; Chromatography, High | 1994 |
1-Methyl-4-phenylpyridinium has greater neurotoxic effect after selenium deficiency than after vitamin E deficiency in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Dopamine; Eating; Free Radicals; Glutathione P | 1994 |
Sulfhydryl drugs reduce neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striat | 1993 |
Regional homovanillic acid production in humans.
Topics: Adolescent; Adult; Aged; Autonomic Nervous System; Central Nervous System; Heart Failure; Hemodynami | 1993 |
IDPN-induced monoamine and hydroxyl radical changes in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Dopamine; Homovanillic Acid; Hy | 2000 |
Catecholamines and neurologic diseases (first of two parts).
Topics: Animals; Brain; Catecholamines; Cerebrospinal Fluid; Disease Models, Animal; Homovanillic Acid; Huma | 1975 |
A new approach to the study of neurological diseases using stable isotopes.
Topics: Animals; Biogenic Amines; Brain Chemistry; Gas Chromatography-Mass Spectrometry; Haplorhini; Homovan | 1977 |
Gastrointestinal manifestations of "acquired dysautonomic" syndrome.
Topics: Autonomic Nervous System; Child, Preschool; Diarrhea; Esophagogastric Junction; Esophagus; Female; G | 1979 |
[Metabolites of neurotransmitters in the cerebrospinal fluid in children].
Topics: Adolescent; Child; Child, Preschool; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; In | 1991 |
The effect of age, sex, weight and height on the plasma concentrations in healthy subjects of the acidic metabolites of some biogenic monoamines involved in psychiatric and neurological disorders.
Topics: Adult; Aged; Aging; Biogenic Monoamines; Body Height; Body Weight; Female; Homovanillic Acid; Humans | 1991 |
Influence of oxygen availability on the neurotoxic effect of 6-hydroxydopamine on nigro-striatal dopaminergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atmospheric Pressure; Chromatography, High Pressure Liquid; | 1991 |
Attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity by tobacco smoke.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striat | 1990 |
Study on monoamine metabolite contents of cerebrospinal fluid in patients with neurodegenerative diseases.
Topics: Adult; Aged; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydr | 1986 |
A high dose of MPTP overcomes the protective effect of selegiline against dopaminergic neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striat | 1989 |
Neurochemical effect of lead exposure: a study on catecholamine metabolism.
Topics: Adult; Cross-Sectional Studies; Female; Homovanillic Acid; Humans; Lead Poisoning; Male; Middle Aged | 1989 |
Styrene metabolism and striatal dopamine depletion in rabbits.
Topics: Animals; Corpus Striatum; Dopamine; Glycine; Glyoxylates; Homovanillic Acid; Male; Mandelic Acids; N | 1985 |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amin | 1985 |
Evaluation of the biological activity of several analogs of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus | 1987 |
Differential neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Swiss-Webster mice from different sources.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemist | 1985 |
Involuntary movements other than Parkinsonism: biochemical aspects.
Topics: Acute Disease; Animals; Athetosis; Basal Ganglia; Brain; Dopamine; Fecal Incontinence; Homovanillic | 1973 |
Monitoring phenylalanine-tyrosine metabolism by high-resolution liquid chromatography of urine.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autistic Disorder; Carbidopa; Catechols; Child; Chroma | 1973 |