Page last updated: 2024-10-21

homovanillic acid and Myoclonic Jerk

homovanillic acid has been researched along with Myoclonic Jerk in 14 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Research Excerpts

ExcerptRelevanceReference
"To study the purported role of central monoamine disturbances in the pathophysiology of the opsoclonus-myoclonus syndrome, the serotonin metabolite 5-hydroxyindoleacetic acid and the dopamine metabolite homovanillic acid were measured in cerebrospinal fluid samples from 27 affected children and 47 age- and gender-matched control subjects by high-pressure liquid chromatography with electrochemical detection."9.08Cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in the pediatric opsoclonus-myoclonus syndrome. ( Banasiak, K; Gospe, SM; Huang, Y; Noetzel, MJ; Pranzatelli, MR; Stanley, M; Tate, E, 1995)
"To study the purported role of central monoamine disturbances in the pathophysiology of the opsoclonus-myoclonus syndrome, the serotonin metabolite 5-hydroxyindoleacetic acid and the dopamine metabolite homovanillic acid were measured in cerebrospinal fluid samples from 27 affected children and 47 age- and gender-matched control subjects by high-pressure liquid chromatography with electrochemical detection."5.08Cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in the pediatric opsoclonus-myoclonus syndrome. ( Banasiak, K; Gospe, SM; Huang, Y; Noetzel, MJ; Pranzatelli, MR; Stanley, M; Tate, E, 1995)
"Three patients with postanoxic intention myoclonus, two patients with intention tremor, and one patient with cerebral palsy were administered L-5-hydroxytryptophan (L-5HTP), the precursor of serotonin, in combination with MK 486, a peripheral amino acid decarboxylase inhibitor."3.65Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486. ( Sethy, VH; Van Woert, MH, 1975)
"In 6 patients with intention myoclonus, the cerebrospinal fluid concentration of 5-hydroxyindoleacetic acid, a metabolite of serotonin was found to be significantly decreased."2.64Serotonin and myoclonus. ( Bowers, MB; Jutkowitz, R; Rosenbaum, D; Van Woert, MH, 1976)
"Children with the opsoclonus-myoclonus syndrome (OMS) usually respond to corticotropin (adrenocorticotrophic hormone, ACTH) treatment but the mechanism of benefit is unknown."1.30Monoaminergic effects of high-dose corticotropin in corticotropin-responsive pediatric opsoclonus-myoclonus. ( Goldstein, DS; Goldstein, EM; Holmes, CS; Huang, YY; Ketner, K; Kinast, M; Lange, BM; Pranzatelli, MR; Sanz, A; Shevell, MI; Stanford, RE; Taff, IP; Tate, E, 1998)
"5-Hydroxyindoleacetic acid was significantly lower in patients with myoclonic DAT as compared to patients with nonmyoclonic DAT, but not significantly lower than in control subjects."1.27Cerebrospinal fluid neurochemistry in the myoclonic subtype of Alzheimer's disease. ( Atack, JR; Beal, MF; Daly, E; Friedland, RP; Kaufman, S; Kaye, JA; May, C; Milstien, S; Rapoport, SI; Sweeney, DL, 1988)
"The neurochemical basis of myoclonus responding to 5HT precursors and clonazepam is discussed."1.26Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam. ( Chadwick, D; Hallett, M; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH, 1977)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's5 (35.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Van Woert, MH3
Magnussen, I1
Lowe, YH1
Hwang, EC1
Koh, PS1
Raffensperger, JG1
Berry, S1
Larsen, MB1
Johnstone, HS1
Chou, P1
Luck, SR1
Hammer, M1
Cohn, SL1
Pranzatelli, MR2
Huang, Y1
Tate, E2
Stanley, M1
Noetzel, MJ1
Gospe, SM1
Banasiak, K1
Huang, YY1
Goldstein, DS1
Holmes, CS1
Goldstein, EM1
Ketner, K1
Kinast, M1
Lange, BM1
Sanz, A1
Shevell, MI1
Stanford, RE1
Taff, IP1
Chadwick, D1
Hallett, M1
Harris, R1
Jenner, P1
Reynolds, EH1
Marsden, CD1
Jankovic, J1
Rivera, VM1
McMillen, BA1
Isaac, L1
Jutkowitz, R1
Rosenbaum, D1
Bowers, MB1
Sethy, VH1
Thal, L1
Sharpless, N1
Wolfson, L1
Engel, J1
Katzman, R1
Nagata, R1
Izumi, K1
Iwata, S1
Shimizu, T1
Fukuda, T1
Mitchell, WG1
Snodgrass, SR1
Kaye, JA1
May, C1
Atack, JR1
Daly, E1
Sweeney, DL1
Beal, MF1
Kaufman, S1
Milstien, S1
Friedland, RP1
Rapoport, SI1
Guilleminault, C1
Tharp, BR1
Cousin, D1

Trials

3 trials available for homovanillic acid and Myoclonic Jerk

ArticleYear
Long-term outcome in children with opsoclonus-myoclonus and ataxia and coincident neuroblastoma.
    The Journal of pediatrics, 1994, Volume: 125, Issue:5 Pt 1

    Topics: Abdominal Neoplasms; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Ataxia; Biomarkers; Child

1994
Cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in the pediatric opsoclonus-myoclonus syndrome.
    Annals of neurology, 1995, Volume: 37, Issue:2

    Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Chromatography, High Pressure Liquid; Electrochemi

1995
Serotonin and myoclonus.
    Monographs in neural sciences, 1976, Volume: 3

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clinical Trials as Topic; Epilepsy; Female; Homov

1976

Other Studies

11 other studies available for homovanillic acid and Myoclonic Jerk

ArticleYear
Study of serotonin in neuropsychiatric disorders.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1982, Volume: 30, Issue:8

    Topics: 5-Hydroxytryptophan; Carbidopa; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetic

1982
Monoaminergic effects of high-dose corticotropin in corticotropin-responsive pediatric opsoclonus-myoclonus.
    Movement disorders : official journal of the Movement Disorder Society, 1998, Volume: 13, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenocorticotropic Hormone; Catecholamines; Child, Preschool; Dihyd

1998
Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.
    Brain : a journal of neurology, 1977, Volume: 100, Issue:3

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzodiazepinones; Carbidopa; Child, Preschool; Clonaz

1977
Hereditary myoclonus and progressive distal muscular atrophy.
    Annals of neurology, 1979, Volume: 6, Issue:3

    Topics: Adult; Aged; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Muscular Atrophy; My

1979
Relationship between kindled myoclonic seizures and feline brain dopamine metabolism.
    Brain research, 1978, Jul-14, Volume: 150, Issue:2

    Topics: Animals; Brain; Cats; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Female; Homovanil

1978
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
    Neurology, 1975, Volume: 25, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cer

1975
Clinical and metabolic observations on the treatment of myoclonus with L-5-HTP and carbidopa.
    Transactions of the American Neurological Association, 1976, Volume: 101

    Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Homovanillic Acid; Humans; Hydrazines; Hydro

1976
Mechanisms of veratramine-induced 5-HT syndrome in mice.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Aci

1991
Opsoclonus-ataxia due to childhood neural crest tumors: a chronic neurologic syndrome.
    Journal of child neurology, 1990, Volume: 5, Issue:2

    Topics: Abdominal Neoplasms; Cerebellar Ataxia; Child, Preschool; Diagnosis, Differential; Eye Movements; Fe

1990
Cerebrospinal fluid neurochemistry in the myoclonic subtype of Alzheimer's disease.
    Annals of neurology, 1988, Volume: 24, Issue:5

    Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Analysis of Variance; Biopterins; Female; Homovanilli

1988
HVA and 5HIAA CSF measurements and 5HTP trials in some patients with involuntary movements.
    Journal of the neurological sciences, 1973, Volume: 18, Issue:4

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Chorea; Dopamine; Dystonia Musculorum Deformans; Femal

1973