homovanillic acid has been researched along with Macular Edema in 1 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Macular Edema: Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)
| Excerpt | Relevance | Reference |
|---|---|---|
| " This indicates the following metabolic derangements in DME: (a) a higher amount of oxidized fatty acids but a lower amount of endogenous antioxidants (oxidative stress); (b) higher levels of β-glucose and homocysteine but a lower level of sorbitol (hyperglycemia); (c) a higher amount of prostaglandin metabolites (inflammation); (d) higher amounts of acylcarnitines, odd-numbered fatty acids, and 7,8-diaminononanoate (respiration deterioration); (e) a higher amount of neurotransmitter metabolites and homovanillic acid (neuronal damage); (f) a lower amount of extracellular matrix (ECM) constituents (ECM deterioration); and (g) a higher amount of di-amino peptides (microvascular damage)." | 4.12 | Untargeted metabolomic analysis of aqueous humor in diabetic macular edema. ( Bakthavatsalam, M; Brelen, ME; Chan, KP; Chan, TI; Chu, KO; Pang, CP; Wang, CC; Yip, YW, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, KO | 1 |
| Chan, TI | 1 |
| Chan, KP | 1 |
| Yip, YW | 1 |
| Bakthavatsalam, M | 1 |
| Wang, CC | 1 |
| Pang, CP | 1 |
| Brelen, ME | 1 |
1 other study available for homovanillic acid and Macular Edema
| Article | Year |
|---|---|
Untargeted metabolomic analysis of aqueous humor in diabetic macular edema.
Topics: Antioxidants; Aqueous Humor; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Fatty Acids; Glucose; | 2022 |