Page last updated: 2024-10-21

homovanillic acid and MS (Multiple Sclerosis)

homovanillic acid has been researched along with MS (Multiple Sclerosis) in 12 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Research Excerpts

ExcerptRelevanceReference
"Ventricular fluid concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA), the respective metabolites of dopamine and serotonin, were measured in 57 patients undergoing thalamotomy for relief of movement disorders."7.66Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders. ( Sharpless, NS; Tabaddor, K; Wolfson, LI, 1978)
"Homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 4-hydroxy-3-methoxyphenylglycol (HMPG) were measured in the cerebrospinal fluid from patients with multiple sclerosis and from healthy volunteers."3.66Monoamine metabolites in successive samples of spinal fluid. A comparison between healthy volunteers and patients with multiple sclerosis. ( Andersen, O; Johansson, BB; Svennerholm, L, 1981)
"Ventricular fluid concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA), the respective metabolites of dopamine and serotonin, were measured in 57 patients undergoing thalamotomy for relief of movement disorders."3.66Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders. ( Sharpless, NS; Tabaddor, K; Wolfson, LI, 1978)
"The concentrations of homovanillic acid (HVA), 5-hydroxyindolylacetic acid (5-HIAA), and 4-hydroxy, 3-methoxyphenylethylene glycol (MHPG) were estimated in the lumbar cerebrospinal fluid (CSF) of control subjects and in some patients who probably, and others who definitely, suffered from multiple sclerosis (MS)."3.65Monoamine metabolites in cerebrospinal fluid in multiple sclerosis. ( Davidson, D; Kinloch, N; Mawdsley, C; Pullar, IA; Yates, CM, 1977)
"Homovanillic acid levels were significantly lower only in the PRMS group, with a negative correlation to duration of illness, and a strong negative correlation to EDSS score, but not to MSSS."1.35Relationship of CSF neurotransmitter metabolite levels to disease severity and disability in multiple sclerosis. ( Evangelopoulos, ME; Karahalios, G; Koutsis, G; Mandellos, D; Markianos, M; Sfagos, C, 2009)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Markianos, M1
Koutsis, G1
Evangelopoulos, ME1
Mandellos, D1
Karahalios, G1
Sfagos, C1
Andersen, O1
Johansson, BB1
Svennerholm, L1
Perry, TL1
Ito, M1
Jones, K1
Hansen, S1
Cook, A1
Nidzgorski, F1
Hurwic, M1
Winsberg, B1
Klutch, A1
Moskowitz, MA1
Wurtman, RJ1
Tabaddor, K1
Wolfson, LI2
Sharpless, NS2
Davidson, D1
Pullar, IA1
Mawdsley, C1
Kinloch, N1
Yates, CM1
Hyyppä, MT1
Jolma, T1
Riekkinen, P2
Rinne, UK2
Thal, LJ1
Curzon, G2
Sonninen, V1
Claveria, LE1
Harrison, MJ1
Kantamaneni, BD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Examination of Potential Neurochemical and Cognitive Mediators of the Relationship Between Mindfulness and Emotion Regulation in Individuals With Multiple Sclerosis: An Internet Based Self-Guided Pilot Study.[NCT02391298]26 participants (Actual)Interventional2014-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for homovanillic acid and MS (Multiple Sclerosis)

ArticleYear
Catecholamines and neurologic diseases (second of two parts).
    The New England journal of medicine, 1975, Aug-14, Volume: 293, Issue:7

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Brain Diseases; Catecholamines; Cereb

1975

Trials

1 trial available for homovanillic acid and MS (Multiple Sclerosis)

ArticleYear
Effects of L-tryptophan treatment on central indoleamine metabolism and short-lasting neurologic disturbances in multiple sclerosis.
    Journal of neural transmission, 1975, Volume: 37, Issue:4

    Topics: Adult; Benserazide; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Multiple Scler

1975

Other Studies

10 other studies available for homovanillic acid and MS (Multiple Sclerosis)

ArticleYear
Relationship of CSF neurotransmitter metabolite levels to disease severity and disability in multiple sclerosis.
    Journal of neurochemistry, 2009, Volume: 108, Issue:1

    Topics: Adolescent; Adult; Disability Evaluation; Disease Progression; Female; Homovanillic Acid; Humans; Hy

2009
Monoamine metabolites in successive samples of spinal fluid. A comparison between healthy volunteers and patients with multiple sclerosis.
    Acta neurologica Scandinavica, 1981, Volume: 63, Issue:4

    Topics: Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglyc

1981
Elevation of gamma-aminobutyric acid in human brain may increase dopaminergic neuronal function.
    Neuroscience letters, 1984, Sep-07, Volume: 50, Issue:1-3

    Topics: Brain; Brain Chemistry; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Huntington Dis

1984
Monoamine accumulation among sclerotic patients receiving dorsal-column stimulation.
    Lancet (London, England), 1978, Jan-07, Volume: 1, Issue:8054

    Topics: Amyotrophic Lateral Sclerosis; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Multiple Scleros

1978
Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders.
    Neurology, 1978, Volume: 28, Issue:12

    Topics: Adult; Aged; Cerebral Palsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Middle A

1978
Monoamine metabolites in cerebrospinal fluid in multiple sclerosis.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:8

    Topics: Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglyc

1977
Diminished levels of ventricular fluid norepinephrine metabolite and somatostatin in childhood-onset dystonia.
    Advances in neurology, 1988, Volume: 50

    Topics: Adolescent; Adult; Age Factors; Cerebral Palsy; Child; Child, Preschool; Dystonia; Homovanillic Acid

1988
Involuntary movements other than Parkinsonism: biochemical aspects.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:9

    Topics: Acute Disease; Animals; Athetosis; Basal Ganglia; Brain; Dopamine; Fecal Incontinence; Homovanillic

1973
Acid monoamine metabolites in cerebrospinal fluid in multiple sclerosis.
    Neurology, 1973, Volume: 23, Issue:7

    Topics: Acute Disease; Adult; Brain; Chronic Disease; Demyelinating Diseases; Female; Homovanillic Acid; Hum

1973
Amine metabolites in the cerebrospinal fluid of patients with disseminated sclerosis.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:6

    Topics: Cerebellar Diseases; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Multiple Sclerosis; Phenyl

1974