homovanillic acid has been researched along with MS (Multiple Sclerosis) in 12 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ventricular fluid concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA), the respective metabolites of dopamine and serotonin, were measured in 57 patients undergoing thalamotomy for relief of movement disorders." | 7.66 | Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders. ( Sharpless, NS; Tabaddor, K; Wolfson, LI, 1978) |
| "Homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 4-hydroxy-3-methoxyphenylglycol (HMPG) were measured in the cerebrospinal fluid from patients with multiple sclerosis and from healthy volunteers." | 3.66 | Monoamine metabolites in successive samples of spinal fluid. A comparison between healthy volunteers and patients with multiple sclerosis. ( Andersen, O; Johansson, BB; Svennerholm, L, 1981) |
| "Ventricular fluid concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA), the respective metabolites of dopamine and serotonin, were measured in 57 patients undergoing thalamotomy for relief of movement disorders." | 3.66 | Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders. ( Sharpless, NS; Tabaddor, K; Wolfson, LI, 1978) |
| "The concentrations of homovanillic acid (HVA), 5-hydroxyindolylacetic acid (5-HIAA), and 4-hydroxy, 3-methoxyphenylethylene glycol (MHPG) were estimated in the lumbar cerebrospinal fluid (CSF) of control subjects and in some patients who probably, and others who definitely, suffered from multiple sclerosis (MS)." | 3.65 | Monoamine metabolites in cerebrospinal fluid in multiple sclerosis. ( Davidson, D; Kinloch, N; Mawdsley, C; Pullar, IA; Yates, CM, 1977) |
| "Homovanillic acid levels were significantly lower only in the PRMS group, with a negative correlation to duration of illness, and a strong negative correlation to EDSS score, but not to MSSS." | 1.35 | Relationship of CSF neurotransmitter metabolite levels to disease severity and disability in multiple sclerosis. ( Evangelopoulos, ME; Karahalios, G; Koutsis, G; Mandellos, D; Markianos, M; Sfagos, C, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (91.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Markianos, M | 1 |
| Koutsis, G | 1 |
| Evangelopoulos, ME | 1 |
| Mandellos, D | 1 |
| Karahalios, G | 1 |
| Sfagos, C | 1 |
| Andersen, O | 1 |
| Johansson, BB | 1 |
| Svennerholm, L | 1 |
| Perry, TL | 1 |
| Ito, M | 1 |
| Jones, K | 1 |
| Hansen, S | 1 |
| Cook, A | 1 |
| Nidzgorski, F | 1 |
| Hurwic, M | 1 |
| Winsberg, B | 1 |
| Klutch, A | 1 |
| Moskowitz, MA | 1 |
| Wurtman, RJ | 1 |
| Tabaddor, K | 1 |
| Wolfson, LI | 2 |
| Sharpless, NS | 2 |
| Davidson, D | 1 |
| Pullar, IA | 1 |
| Mawdsley, C | 1 |
| Kinloch, N | 1 |
| Yates, CM | 1 |
| Hyyppä, MT | 1 |
| Jolma, T | 1 |
| Riekkinen, P | 2 |
| Rinne, UK | 2 |
| Thal, LJ | 1 |
| Curzon, G | 2 |
| Sonninen, V | 1 |
| Claveria, LE | 1 |
| Harrison, MJ | 1 |
| Kantamaneni, BD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Examination of Potential Neurochemical and Cognitive Mediators of the Relationship Between Mindfulness and Emotion Regulation in Individuals With Multiple Sclerosis: An Internet Based Self-Guided Pilot Study.[NCT02391298] | 26 participants (Actual) | Interventional | 2014-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for homovanillic acid and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Catecholamines and neurologic diseases (second of two parts).
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Brain Diseases; Catecholamines; Cereb | 1975 |
1 trial available for homovanillic acid and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Effects of L-tryptophan treatment on central indoleamine metabolism and short-lasting neurologic disturbances in multiple sclerosis.
Topics: Adult; Benserazide; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Multiple Scler | 1975 |
10 other studies available for homovanillic acid and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Relationship of CSF neurotransmitter metabolite levels to disease severity and disability in multiple sclerosis.
Topics: Adolescent; Adult; Disability Evaluation; Disease Progression; Female; Homovanillic Acid; Humans; Hy | 2009 |
Monoamine metabolites in successive samples of spinal fluid. A comparison between healthy volunteers and patients with multiple sclerosis.
Topics: Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglyc | 1981 |
Elevation of gamma-aminobutyric acid in human brain may increase dopaminergic neuronal function.
Topics: Brain; Brain Chemistry; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Huntington Dis | 1984 |
Monoamine accumulation among sclerotic patients receiving dorsal-column stimulation.
Topics: Amyotrophic Lateral Sclerosis; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Multiple Scleros | 1978 |
Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders.
Topics: Adult; Aged; Cerebral Palsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Middle A | 1978 |
Monoamine metabolites in cerebrospinal fluid in multiple sclerosis.
Topics: Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglyc | 1977 |
Diminished levels of ventricular fluid norepinephrine metabolite and somatostatin in childhood-onset dystonia.
Topics: Adolescent; Adult; Age Factors; Cerebral Palsy; Child; Child, Preschool; Dystonia; Homovanillic Acid | 1988 |
Involuntary movements other than Parkinsonism: biochemical aspects.
Topics: Acute Disease; Animals; Athetosis; Basal Ganglia; Brain; Dopamine; Fecal Incontinence; Homovanillic | 1973 |
Acid monoamine metabolites in cerebrospinal fluid in multiple sclerosis.
Topics: Acute Disease; Adult; Brain; Chronic Disease; Demyelinating Diseases; Female; Homovanillic Acid; Hum | 1973 |
Amine metabolites in the cerebrospinal fluid of patients with disseminated sclerosis.
Topics: Cerebellar Diseases; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Multiple Sclerosis; Phenyl | 1974 |