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homovanillic acid and Hepatolenticular Degeneration

homovanillic acid has been researched along with Hepatolenticular Degeneration in 7 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.

Research Excerpts

ExcerptRelevanceReference
"Treatment with tetrabenazine did not significantly alter the metabolite levels in patients in whom it produced either improvement, or side effects."1.26CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders. ( Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM, 1977)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SANKOFF, I1
SOURKES, TL1
Nyberg, P1
Gottfries, CG1
Holmgren, G1
Persson, S1
Roos, BE1
Winblad, B1
Barkhatova, VP1
Saito, T1
Nagao, T1
Okabe, M1
Saito, K1
Davidson, DL1
Yates, CM1
Mawdsley, C1
Pullar, IA1
Wilson, H1
Nijeholt, JL1
Korf, J1
Gelmers, HJ1
Troost, J1
Willemse, J1

Other Studies

7 other studies available for homovanillic acid and Hepatolenticular Degeneration

ArticleYear
Determination by thin-layer chromatography of urinary homovanillic acid in normal and disease states.
    Canadian journal of biochemistry and physiology, 1963, Volume: 41

    Topics: Chorea; Chromatography, Thin Layer; Ganglioneuroma; Hepatolenticular Degeneration; Homovanillic Acid

1963
Advanced catecholaminergic disturbances in the brain in a case of Wilson's disease.
    Acta neurologica Scandinavica, 1982, Volume: 65, Issue:1

    Topics: Adolescent; Brain; Catecholamines; Dopamine; Female; Hepatolenticular Degeneration; Homovanillic Aci

1982
[Role of catecholamines in the biochemical mechanisms of the pathogenesis of hepatocerebral dystrophy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:7

    Topics: Adolescent; Adult; Catecholamines; Copper; Dopamine; Dopamine beta-Hydroxylase; Epinephrine; Hepatol

1982
Neurochemical and histochemical evidence for an abnormal catecholamine metabolism in the cerebral cortex of the Long-Evans Cinnamon rat before excessive copper accumulation in the brain.
    Neuroscience letters, 1996, Oct-04, Volume: 216, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Copper; Dopamine; Hepatolenticular

1996
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:12

    Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans;

1977
Wilson's disease and monoamines.
    Archives of neurology, 1978, Volume: 35, Issue:9

    Topics: Adult; Hepatolenticular Degeneration; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Pen

1978
Wilson's disease: modification by L-DOPA.
    Neuropadiatrie, 1973, Volume: 4, Issue:4

    Topics: Adolescent; Chelating Agents; Copper; Dihydroxyphenylalanine; Evaluation Studies as Topic; Hepatolen

1973