homovanillic acid has been researched along with Hepatolenticular Degeneration in 7 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with tetrabenazine did not significantly alter the metabolite levels in patients in whom it produced either improvement, or side effects." | 1.26 | CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders. ( Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SANKOFF, I | 1 |
| SOURKES, TL | 1 |
| Nyberg, P | 1 |
| Gottfries, CG | 1 |
| Holmgren, G | 1 |
| Persson, S | 1 |
| Roos, BE | 1 |
| Winblad, B | 1 |
| Barkhatova, VP | 1 |
| Saito, T | 1 |
| Nagao, T | 1 |
| Okabe, M | 1 |
| Saito, K | 1 |
| Davidson, DL | 1 |
| Yates, CM | 1 |
| Mawdsley, C | 1 |
| Pullar, IA | 1 |
| Wilson, H | 1 |
| Nijeholt, JL | 1 |
| Korf, J | 1 |
| Gelmers, HJ | 1 |
| Troost, J | 1 |
| Willemse, J | 1 |
7 other studies available for homovanillic acid and Hepatolenticular Degeneration
| Article | Year |
|---|---|
Determination by thin-layer chromatography of urinary homovanillic acid in normal and disease states.
Topics: Chorea; Chromatography, Thin Layer; Ganglioneuroma; Hepatolenticular Degeneration; Homovanillic Acid | 1963 |
Advanced catecholaminergic disturbances in the brain in a case of Wilson's disease.
Topics: Adolescent; Brain; Catecholamines; Dopamine; Female; Hepatolenticular Degeneration; Homovanillic Aci | 1982 |
[Role of catecholamines in the biochemical mechanisms of the pathogenesis of hepatocerebral dystrophy].
Topics: Adolescent; Adult; Catecholamines; Copper; Dopamine; Dopamine beta-Hydroxylase; Epinephrine; Hepatol | 1982 |
Neurochemical and histochemical evidence for an abnormal catecholamine metabolism in the cerebral cortex of the Long-Evans Cinnamon rat before excessive copper accumulation in the brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Copper; Dopamine; Hepatolenticular | 1996 |
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; | 1977 |
Wilson's disease and monoamines.
Topics: Adult; Hepatolenticular Degeneration; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Pen | 1978 |
Wilson's disease: modification by L-DOPA.
Topics: Adolescent; Chelating Agents; Copper; Dihydroxyphenylalanine; Evaluation Studies as Topic; Hepatolen | 1973 |