homovanillic acid has been researched along with Epilepsy, Temporal Lobe in 7 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 7.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 3.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| "Homovanillic acid accumulation was decreased in this group." | 1.26 | Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology. ( Peters, JG, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rocha, L | 1 |
| Alonso-Vanegas, M | 1 |
| Villeda-Hernández, J | 1 |
| Mújica, M | 1 |
| Cisneros-Franco, JM | 1 |
| López-Gómez, M | 1 |
| Zavala-Tecuapetla, C | 1 |
| Frías-Soria, CL | 1 |
| Segovia-Vila, J | 1 |
| Borsodi, A | 1 |
| Fukuda, M | 1 |
| Niwa, SI | 1 |
| Kumagai, N | 1 |
| Nagakubo, S | 1 |
| Shirayama, Y | 1 |
| Hashimoto, O | 1 |
| Hata, A | 1 |
| Kameyama, T | 1 |
| Anzai, N | 1 |
| Peters, JG | 1 |
| Shaywitz, BA | 1 |
| Cohen, DJ | 1 |
| Bowers, MB | 1 |
| Kobayashi, K | 1 |
| Ebara, Y | 1 |
| Hosokawa, K | 1 |
| Oku, Y | 1 |
| Riekkinen, PJ | 1 |
| Pitkänen, A | 1 |
| Halonen, T | 1 |
| Lehtinen, M | 1 |
| Ylinen, A | 1 |
| Sivenius, J | 1 |
| Garelis, E | 1 |
| Sourkes, TL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for homovanillic acid and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Effect of gamma-vinyl GABA treatment on cholinergic and aminergic neurotransmission and on cyclic nucleotides in human complex partial epilepsy--a CSF study.
Topics: Acetylcholinesterase; Adult; Aminocaproates; Anticonvulsants; Brain; Epilepsy, Temporal Lobe; Female | 1988 |
6 other studies available for homovanillic acid and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Dopamine abnormalities in the neocortex of patients with temporal lobe epilepsy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Dopamine; Epilepsy, Temporal Lobe; Female; Homovanillic Acid; | 2012 |
Compensatory function of central dopaminergic system for suppressing psychic seizures--repeated plasma homovanillic acid measurement in refractory temporal lobe epilepsy.
Topics: Adult; Chromatography, High Pressure Liquid; Epilepsy, Temporal Lobe; Female; Hallucinations; Homova | 1993 |
Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology.
Topics: Adolescent; Adult; Child; Dopamine; Epilepsy, Temporal Lobe; Homovanillic Acid; Humans; Hydroxyindol | 1979 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy | 1975 |
[Homovanillic acid concentration of the cerebrospinal fluid in epilepsy].
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Ab | 1976 |
Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man.
Topics: Adolescent; Adult; Brain Diseases; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovani | 1974 |