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homovanillic acid and Epilepsy, Temporal Lobe

homovanillic acid has been researched along with Epilepsy, Temporal Lobe in 7 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).

Research Excerpts

ExcerptRelevanceReference
"Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)."7.65Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975)
"Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)."3.65Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975)
"Homovanillic acid accumulation was decreased in this group."1.26Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology. ( Peters, JG, 1979)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rocha, L1
Alonso-Vanegas, M1
Villeda-Hernández, J1
Mújica, M1
Cisneros-Franco, JM1
López-Gómez, M1
Zavala-Tecuapetla, C1
Frías-Soria, CL1
Segovia-Vila, J1
Borsodi, A1
Fukuda, M1
Niwa, SI1
Kumagai, N1
Nagakubo, S1
Shirayama, Y1
Hashimoto, O1
Hata, A1
Kameyama, T1
Anzai, N1
Peters, JG1
Shaywitz, BA1
Cohen, DJ1
Bowers, MB1
Kobayashi, K1
Ebara, Y1
Hosokawa, K1
Oku, Y1
Riekkinen, PJ1
Pitkänen, A1
Halonen, T1
Lehtinen, M1
Ylinen, A1
Sivenius, J1
Garelis, E1
Sourkes, TL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822]550 participants (Anticipated)Observational2022-02-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for homovanillic acid and Epilepsy, Temporal Lobe

ArticleYear
Effect of gamma-vinyl GABA treatment on cholinergic and aminergic neurotransmission and on cyclic nucleotides in human complex partial epilepsy--a CSF study.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:1

    Topics: Acetylcholinesterase; Adult; Aminocaproates; Anticonvulsants; Brain; Epilepsy, Temporal Lobe; Female

1988

Other Studies

6 other studies available for homovanillic acid and Epilepsy, Temporal Lobe

ArticleYear
Dopamine abnormalities in the neocortex of patients with temporal lobe epilepsy.
    Neurobiology of disease, 2012, Volume: 45, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Dopamine; Epilepsy, Temporal Lobe; Female; Homovanillic Acid;

2012
Compensatory function of central dopaminergic system for suppressing psychic seizures--repeated plasma homovanillic acid measurement in refractory temporal lobe epilepsy.
    Epilepsy research, 1993, Volume: 14, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Epilepsy, Temporal Lobe; Female; Hallucinations; Homova

1993
Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology.
    European neurology, 1979, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Child; Dopamine; Epilepsy, Temporal Lobe; Homovanillic Acid; Humans; Hydroxyindol

1979
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
    Neurology, 1975, Volume: 25, Issue:1

    Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy

1975
[Homovanillic acid concentration of the cerebrospinal fluid in epilepsy].
    No to shinkei = Brain and nerve, 1976, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Ab

1976
Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Brain Diseases; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovani

1974