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homovanillic acid and Cognition Disorders

homovanillic acid has been researched along with Cognition Disorders in 23 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"In this study we investigated the cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in Alzheimer (AD) patients (n=75), patients with mild cognitive impairment (MCI, n=9) and patients with depression (n=7)."7.725-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment. ( Ganzer, S; Müller-Thomsen, T; Stuerenburg, HJ, 2004)
" In the present study, we examined the association between blood levels of 3-methoxy-4-hydroxyphenylglycol (MHPG), homovanillic acid (HVA), or brain-derived neurotrophic factor (BDNF) and scores on the Wisconsin Card Sorting Test (WCST) in patients with early-stage schizophrenia."3.75Associations between plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) and negative symptoms or cognitive impairments in early-stage schizophrenia. ( Goto, N; Hayashi, K; Hori, H; Ikenouchi-Sugita, A; Kakeda, S; Korogi, Y; Moriya, J; Nakamura, J; Ueda, N; Umene-Nakano, W; Yoshimura, R, 2009)
"In this study we investigated the cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in Alzheimer (AD) patients (n=75), patients with mild cognitive impairment (MCI, n=9) and patients with depression (n=7)."3.725-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment. ( Ganzer, S; Müller-Thomsen, T; Stuerenburg, HJ, 2004)
"Lewy body disorders, including Parkinson's disease (PD), Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), are characterized by profound central and peripheral monoaminergic dysfunction."1.48Monoaminergic Markers Across the Cognitive Spectrum of Lewy Body Disease. ( Aerts, T; De Deyn, PP; Fransen, E; Gerritsen, MJ; Spikman, JM; Van Dam, D; van der Zee, S; van Laar, T; Vermeiren, Y, 2018)
"Schizophrenia is associated with multiple cognitive deficits which in turn may be related to abnormal dopamine (DA) function."1.29Neuropsychological correlates of central monoamine function in chronic schizophrenia: relationship between CSF metabolites and cognitive function. ( Apter, S; Davidson, M; Davis, KL; Harvey, PD; Kahn, RS; Keefe, RS; Mohs, RC; Neale, JM, 1994)
"In patients with Parkinson's disease the levels of somatostatin-like immunoreactivity were lower than in controls (P less than ."1.28Somatostatin-like immunoreactivity in the cerebrospinal fluid of aged patients with Parkinson's disease. The effect of dopatherapy. ( Cramer, H; Kuntzmann, F; Masson, H; Popescu, I; Strubel, D, 1990)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19907 (30.43)18.7374
1990's6 (26.09)18.2507
2000's6 (26.09)29.6817
2010's4 (17.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van der Zee, S1
Vermeiren, Y1
Fransen, E1
Van Dam, D1
Aerts, T1
Gerritsen, MJ1
Spikman, JM1
van Laar, T1
De Deyn, PP1
Evers, LJ1
Curfs, LM1
Bakker, JA1
Boot, E1
da Silva Alves, F1
Abeling, N1
Bierau, J1
Drukker, M1
van Amelsvoort, TA1
Aguiar, AS1
Lopes, SC1
Tristão, FS1
Rial, D1
de Oliveira, G1
da Cunha, C1
Raisman-Vozari, R1
Prediger, RD1
Goto, N1
Yoshimura, R1
Kakeda, S1
Moriya, J1
Hayashi, K1
Ikenouchi-Sugita, A1
Umene-Nakano, W1
Hori, H1
Ueda, N1
Korogi, Y1
Nakamura, J1
Kumar, AM1
Ownby, RL1
Waldrop-Valverde, D1
Fernandez, B1
Kumar, M1
Pomara, N1
Willoughby, LM1
Hashim, A1
Sershen, H1
Sidtis, JJ1
Wesnes, K1
Greenblatt, DJ1
Lajtha, A1
Stuerenburg, HJ1
Ganzer, S1
Müller-Thomsen, T1
Castner, SA1
Vosler, PS1
Goldman-Rakic, PS1
Leckman, JF1
Cohen, DJ1
Shaywitz, BA1
Caparulo, BK1
Heninger, GR1
Bowers, MB1
McEntee, WJ1
Mair, RG1
Langlais, PJ1
Mann, JJ1
Stanley, M1
Neophytides, A1
de Leon, MJ1
Ferris, SH1
Gershon, S2
Kahn, RS1
Harvey, PD1
Davidson, M1
Keefe, RS1
Apter, S1
Neale, JM1
Mohs, RC1
Davis, KL1
Gilbertson, MW1
Yao, JK1
van Kammen, DP1
Sheline, YI1
Miller, K1
Bardgett, ME1
Csernansky, JG1
Poirier, MF1
Heim, C1
Zhang, J1
Lan, J1
Sieklucka, M1
Kurz, T1
Riederer, P1
Gerlach, M1
Sontag, KH1
del Ser, T1
Masson, H1
Popescu, I1
Strubel, D1
Cramer, H1
Kuntzmann, F1
Hildebrand, J1
Bourgeois, F1
Buyse, M1
Przedborski, S1
Goldman, S1
Mayeux, R1
Stern, Y1
Sano, M1
Cote, L1
Williams, JB1
Palmer, AM1
Francis, PT1
Bowen, DM1
Benton, JS1
Neary, D1
Mann, DM1
Snowden, JS1
Portin, R1
Rinne, UK1
Angrist, B1
Sathananthan, G1
Wilk, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00004325]200 participants Observational1988-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for homovanillic acid and Cognition Disorders

ArticleYear
[Biological approaches to acute psychoses].
    L'Encephale, 1999, Volume: 25 Spec No 3

    Topics: Acute Disease; Antipsychotic Agents; Brain; Cognition Disorders; Homovanillic Acid; Humans; Magnetic

1999
[Clinical manifestation of frontotemporal dementia].
    Neurologia (Barcelona, Spain), 2000, Volume: 15 Suppl 1

    Topics: Alzheimer Disease; Atrophy; Cognition Disorders; Diagnosis, Differential; Frontal Lobe; Homovanillic

2000

Trials

2 trials available for homovanillic acid and Cognition Disorders

ArticleYear
Effects of acute lorazepam administration on aminergic activity in normal elderly subjects: relationship to performance effects and apolipoprotein genotype.
    Neurochemical research, 2004, Volume: 29, Issue:7

    Topics: Aged; Analysis of Variance; Anti-Anxiety Agents; Apolipoprotein E4; Apolipoproteins; Apolipoproteins

2004
Memory and plasma HVA changes in schizophrenia: are they episode markers?
    Biological psychiatry, 1994, Feb-01, Volume: 35, Issue:3

    Topics: Adult; Biomarkers; Cognition Disorders; Double-Blind Method; Haloperidol; Homovanillic Acid; Humans;

1994

Other Studies

19 other studies available for homovanillic acid and Cognition Disorders

ArticleYear
Monoaminergic Markers Across the Cognitive Spectrum of Lewy Body Disease.
    Journal of Parkinson's disease, 2018, Volume: 8, Issue:1

    Topics: Aged; Biogenic Monoamines; Biomarkers; Cognition Disorders; Cognitive Dysfunction; Diagnosis, Differ

2018
Serotonergic, noradrenergic and dopaminergic markers are related to cognitive function in adults with 22q11 deletion syndrome.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:8

    Topics: 22q11 Deletion Syndrome; Adult; Biomarkers; Case-Control Studies; Cognition Disorders; Dopamine; Fem

2014
Exercise Improves Cognitive Impairment and Dopamine Metabolism in MPTP-Treated Mice.
    Neurotoxicity research, 2016, Volume: 29, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catale

2016
Associations between plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) and negative symptoms or cognitive impairments in early-stage schizophrenia.
    Human psychopharmacology, 2009, Volume: 24, Issue:8

    Topics: Adolescent; Adult; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Cognition Disorders; Fem

2009
Human immunodeficiency virus infection in the CNS and decreased dopamine availability: relationship with neuropsychological performance.
    Journal of neurovirology, 2011, Volume: 17, Issue:1

    Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Brain; Cognition Disorders; Dopamine; Female; HI

2011
5-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment.
    Neuro endocrinology letters, 2004, Volume: 25, Issue:6

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Depression; Dopamine; Female; Homovanillic Acid; Human

2004
Amphetamine sensitization impairs cognition and reduces dopamine turnover in primate prefrontal cortex.
    Biological psychiatry, 2005, Apr-01, Volume: 57, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Centra

2005
CSF monoamine metabolites in child and adult psychiatric patients. A developmental perspective.
    Archives of general psychiatry, 1980, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Autistic Disorder; Bipolar Disorder; Child; Child, Preschool;

1980
Neurochemical pathology in Korsakoff's psychosis: implications for other cognitive disorders.
    Neurology, 1984, Volume: 34, Issue:5

    Topics: Alcohol Amnestic Disorder; Cognition Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacet

1984
Central amine metabolism in Alzheimer's disease: in vivo relationship to cognitive deficit.
    Neurobiology of aging, 1981,Spring, Volume: 2, Issue:1

    Topics: Aged; Alzheimer Disease; Blood Platelets; Cognition Disorders; Dementia; Glycols; Homovanillic Acid;

1981
Neuropsychological correlates of central monoamine function in chronic schizophrenia: relationship between CSF metabolites and cognitive function.
    Schizophrenia research, 1994, Volume: 11, Issue:3

    Topics: Adult; Cerebral Cortex; Cognition Disorders; Discrimination Learning; Dopamine; Homovanillic Acid; H

1994
Higher cerebrospinal fluid MHPG in subjects with dementia of the Alzheimer type. Relationship with cognitive dysfunction.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1998,Spring, Volume: 6, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Female; Homovanillic Acid; Humans;

1998
Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies.
    The European journal of neuroscience, 2000, Volume: 12, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carotid Stenosis; Cognition Disorders; Corpu

2000
Somatostatin-like immunoreactivity in the cerebrospinal fluid of aged patients with Parkinson's disease. The effect of dopatherapy.
    Journal of the American Geriatrics Society, 1990, Volume: 38, Issue:1

    Topics: Aged; Aged, 80 and over; Benserazide; Bromocriptine; Cognition Disorders; Female; Homovanillic Acid;

1990
Reproducibility of monoamine metabolite measurements in human cerebrospinal fluid.
    Acta neurologica Scandinavica, 1990, Volume: 81, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Cognition Disorders; Female; G

1990
Clinical and biochemical correlates of bradyphrenia in Parkinson's disease.
    Neurology, 1987, Volume: 37, Issue:7

    Topics: Aged; Alzheimer Disease; Arousal; Attention; Biogenic Amines; Cognition Disorders; Homovanillic Acid

1987
Catecholaminergic neurones assessed ante-mortem in Alzheimer's disease.
    Brain research, 1987, Jun-30, Volume: 414, Issue:2

    Topics: Adult; Aged; Alzheimer Disease; Catecholamines; Cerebral Cortex; Choline O-Acetyltransferase; Cognit

1987
Predictive factors for cognitive deterioration and dementia in Parkinson's disease.
    Advances in neurology, 1987, Volume: 45

    Topics: Cognition Disorders; Dementia; Electroencephalography; Homovanillic Acid; Humans; Levodopa; Parkinso

1987
Amphetamine psychosis: behavioral and biochemical aspects.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Adolescent; Adult; Affect; Alcoholism; Amphetamine; Brain; Cognition Disorders; Delusions; Depressio

1974