homovanillic acid has been researched along with Cerebral Ischemia in 26 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In rats with cerebral ischemia, a low dose (10 mg/kg, i." | 5.27 | Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia. ( Kakihana, M; Nagai, Y; Nagaoka, A; Nagawa, Y; Narumi, S; Yamazaki, N, 1985) |
| "During 30 minutes of global forebrain ischemia in rats, striatal intracellular levels of dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) increase at the same time extracellular levels, measured by microdialysis, decrease." | 3.69 | Ischemia increases tissue and decreases extracellular levels of acid dopamine metabolites in the rat striatum: further evidence for active transport of metabolites. ( Clemens, JA; Mincy, RE; Phebus, LA, 1995) |
| "For understanding of the role of monoamines in cerebral ischemia, 3-methoxy-4-hydroxyphenylglycol (MHPG), hydroxyindoleacetic acid (5HIAA) homovanillic acid (HVA) the three major monoamine metabolites in CSF of 33 patients and 18 controls were measured with high-performance liquid chromatography." | 3.68 | [The changes of monoamine metabolites in CSF of patients with cerebral stroke]. ( Tang, HZ, 1991) |
| "Rat striatal extracellular fluid levels of dopamine, serotonin, 3-methoxytyramine (3-MT), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) were measured before, during and after transient, global cerebral ischemia in awake rats using in vivo brain microdialysis." | 3.67 | Effects of transient, global, cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites. ( Clemens, JA; Phebus, LA, 1989) |
| "To clarify the rule of monoamine in cerebral ischemia, 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF) of 33 patients and 18 controls were measured with high performance liquid chromatography." | 3.67 | Monoamine metabolites in cerebrospinal fluid during acute cerebral ischemia. ( Huang, YQ; Lu, XF; Ou, YS; Tang, HZ; Wang, KJ, 1989) |
| " In time course and dose-response experiments with ET-1 and in comparisons with ET-3, the volume of the lesions has been determined based mainly on the disappearance of striatal nerve cells, using a computer assisted morphometrical analysis." | 1.28 | Involvement of local ischemia in endothelin-1 induced lesions of the neostriatum of the anaesthetized rat. ( Agnati, LF; Cintra, A; Fuxe, K; Goiny, M; Hallström, A; Kurosawa, N; Rosén, L; Ungerstedt, U, 1992) |
| "In rats with cerebral ischemia, a low dose (10 mg/kg, i." | 1.27 | Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia. ( Kakihana, M; Nagai, Y; Nagaoka, A; Nagawa, Y; Narumi, S; Yamazaki, N, 1985) |
| "The homovanillic acid (HVA) content was decreased significantly at 12 h after occlusion." | 1.27 | Changes in the content of dopamine and its metabolites in the basal ganglia following right middle cerebral artery occlusion and reflow in monkeys. ( Abraham, J; Cherian, R; Kuruvilla, A; Theodore, D, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (46.15) | 18.7374 |
| 1990's | 10 (38.46) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, MS | 1 |
| Fang, C | 1 |
| Xu, J | 1 |
| Zhang, GF | 1 |
| Ge, LB | 1 |
| Okuyama, S | 1 |
| Tashiro, K | 1 |
| Lam, NV | 1 |
| Hatakeyama, T | 1 |
| Terashima, T | 1 |
| Yokogoshi, H | 1 |
| Goyagi, T | 1 |
| Bhardwaj, A | 2 |
| Koehler, RC | 1 |
| Traystman, RJ | 1 |
| Hurn, PD | 1 |
| Kirsch, JR | 1 |
| Jellinger, K | 1 |
| Riederer, P | 1 |
| Stelmasiak, Z | 1 |
| Strasser, A | 1 |
| Yasuma, Y | 1 |
| McCarron, RM | 1 |
| Ishii, H | 1 |
| Stanimirovic, D | 1 |
| Spatz, M | 1 |
| Phebus, LA | 2 |
| Mincy, RE | 1 |
| Clemens, JA | 2 |
| Pastuszko, P | 1 |
| Wilson, DF | 1 |
| Lei, B | 1 |
| Adachi, N | 2 |
| Nagaro, T | 1 |
| Arai, T | 2 |
| Lesser, JB | 1 |
| Koorn, R | 1 |
| Vloka, JD | 1 |
| Kuroda, MM | 1 |
| Thys, DM | 1 |
| Terao, K | 1 |
| Otsuka, R | 1 |
| Luthman, J | 1 |
| Lindqvist, E | 1 |
| Dell'Anna, E | 1 |
| Kojima, H | 1 |
| Shiotani, T | 1 |
| Tachizawa, H | 1 |
| Olson, L | 1 |
| Fuxe, K | 1 |
| Kurosawa, N | 1 |
| Cintra, A | 1 |
| Hallström, A | 1 |
| Goiny, M | 1 |
| Rosén, L | 1 |
| Agnati, LF | 1 |
| Ungerstedt, U | 1 |
| Heyes, MP | 1 |
| Nowak, TS | 1 |
| Tang, HZ | 2 |
| Brannan, T | 1 |
| Weinberger, J | 3 |
| Ferrarese, C | 1 |
| Bassi, S | 1 |
| Frattola, L | 1 |
| Locatelli, P | 1 |
| Piolti, R | 1 |
| Trabucchi, M | 1 |
| Nieves-Rosa, J | 1 |
| Lu, XF | 1 |
| Wang, KJ | 1 |
| Ou, YS | 1 |
| Huang, YQ | 1 |
| Narumi, S | 1 |
| Nagai, Y | 1 |
| Kakihana, M | 1 |
| Yamazaki, N | 1 |
| Nagaoka, A | 1 |
| Nagawa, Y | 1 |
| Matsumoto, T | 1 |
| Obrenovitch, TP | 1 |
| Sarna, GS | 1 |
| Symon, L | 1 |
| Oishi, R | 1 |
| Itoh, Y | 1 |
| Nishibori, M | 1 |
| Watanabe, T | 1 |
| Nishi, H | 1 |
| Saeki, K | 1 |
| Slivka, A | 1 |
| Brannan, TS | 1 |
| Knott, PJ | 1 |
| Cohen, G | 1 |
| Kuruvilla, A | 2 |
| Cherian, R | 2 |
| Theodore, D | 1 |
| Abraham, J | 2 |
| Theodore, DR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers[NCT01086696] | Early Phase 1 | 6 participants (Actual) | Interventional | 2010-03-09 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
26 other studies available for homovanillic acid and Cerebral Ischemia
| Article | Year |
|---|---|
[Dynamic changes of dopamine and its metabolite levels in the rat striatum after cerebral ischemia-reperfusion and electroacupuncture].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Dopamine; Electroacupuncture; Extracellular | 2009 |
Effect of the edible mushroom Mycoleptodonoides aitchisonii on transient global ischemia-induced monoamine metabolism changes in rat cerebral cortex.
Topics: Agaricales; Animals; Biological Products; Brain Ischemia; Carotid Artery Injuries; Cerebral Cortex; | 2012 |
Potent sigma 1-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine provides ischemic neuroprotection without altering dopamine accumulation in vivo in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood Gas Analysis; Body Temperature; Brain Chemistry; Brai | 2003 |
[Central neurotransmitters in cerebral ischemia and stroke].
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cerebral Infarction; Cerebrovascular Diso | 1983 |
Effect of ischemia on monoamine metabolism. Brain monoamine metabolites in cerebrospinal fluid of patients with recent cerebral infarction.
Topics: Aged; Brain Ischemia; Cerebral Infarction; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac | 1982 |
Effect of nitro-L-arginine on cerebral blood flow and monoamine metabolism during ischemia/reperfusion in the mongolian gerbil.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arginine; Biogenic Monoamines; Body T | 1994 |
Ischemia increases tissue and decreases extracellular levels of acid dopamine metabolites in the rat striatum: further evidence for active transport of metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biological Transport, Active; Brain Ischemia; Corpus Striat | 1995 |
Activation of tyrosine hydroxylase in striatum of newborn piglets in response to hypocapnic ischemia and recovery.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Ischemia; Corpus Striatum; Dihydrox | 1997 |
The effect of dopamine depletion on the H2O2 production in the rat striatum following transient middle cerebral artery occlusion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Cerebral Arteries; Dopamine; Homovanillic A | 1997 |
The interaction of temperature with thiopental and etomidate on extracellular dopamine and glutamate levels in Wistar-Kyoto rats subjected to forebrain ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthetics, Intravenous; Animals; Blood Pressure; Brain Ischemia; C | 1999 |
Histaminergic H(2) blockade facilitates ischemic release of dopamine in gerbil striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Corpus Striatum; Dopamine; Gerbillinae; His | 2002 |
Effects of DM-9384, a pyrrolidone derivative, on ischemia-induced changes in the central monoamine systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain Chemistry; Brain Ischemia; Centr | 1992 |
Involvement of local ischemia in endothelin-1 induced lesions of the neostriatum of the anaesthetized rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Cerebrovascular Circulation; Corpus Striatu | 1992 |
Delayed increases in regional brain quinolinic acid follow transient ischemia in the gerbil.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dopamin | 1990 |
[The changes of monoamine metabolites in CSF of patients with cerebral stroke].
Topics: Brain Ischemia; Cerebrovascular Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac | 1991 |
Pentobarbital inhibits extracellular release of dopamine in the ischemic striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Corpus Striatum; Depression, Chemical; Dopa | 1990 |
Different patterns of CSF neurotransmitter metabolism in patients with left or right hemispheric stroke.
Topics: Aged; Biogenic Amines; Brain Ischemia; Female; Functional Laterality; Homovanillic Acid; Humans; Hyd | 1986 |
Metabolism of monoamine neurotransmitters in the evolution of infarction in ischemic striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain Ischemia; Carotid Arteries; Cerebral | 1987 |
Effects of transient, global, cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Corpus Striatum; Dopamine; Extracellular Sp | 1989 |
Monoamine metabolites in cerebrospinal fluid during acute cerebral ischemia.
Topics: Aged; Biogenic Monoamines; Brain Ischemia; Electronic Data Processing; Female; Homovanillic Acid; Hu | 1989 |
Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzoquinones; Biogenic Amines; Brain; Brain Ischemia; Chro | 1985 |
[Extracellular concentration of dopamine and dopamine metabolites in the rat striatum during cerebral ischemia and reperfusion].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Chromatography, High Pressure Liquid; Corpu | 1989 |
Effect of MCI-186 on ischemia-induced changes in monoamine metabolism in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipyrine; Biogenic Monoamines; Brain; Brain Edema; Brain | 1989 |
Increase in extracellular dopamine in the striatum during cerebral ischemia: a study utilizing cerebral microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Carotid Arteries; Corpus Striatum; Dialysis | 1988 |
Changes in the content of dopamine and its metabolites in the basal ganglia following right middle cerebral artery occlusion and reflow in monkeys.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Brain Ischemia; Cerebral Arteries; Constrict | 1987 |
Temporal profile of tissue levels of dopamine and its metabolites, HVA and DOPAC following focal cerebral ischaemia in anaesthetized primates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Brain Ischemia; Dopamine; Female; Homovanill | 1986 |