homovanillic acid has been researched along with Brain Diseases in 36 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of five comatose patients, two had cerebrovascular lesions and three had sustained head injury, and, in four of the five, the values of either one or both of HVA and 5-HIAA were low, but in the fifth case the 5-HIAA value was high." | 5.26 | Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus. ( Inagawa, T; Ishikawa, S; Uozumi, T, 1980) |
| "Baseline concentrations of homovanillic acid (HVA), 5-hydroxyindole acetic acid (5-HIAA) and MHPG in the cerebrospinal fluid (CSF) were determined in 67 lobotomized and 30 non-lobotomized patients with chronic schizophrenia." | 3.66 | Monoamine metabolite levels in cerebrospinal fluid and brain atrophy in lobotomized schizophrenic patients. ( Hyyppä, S; Kampman, R; Myllylä, V; Ranta, P; Rimón, R; Roos, BE, 1979) |
| " All of these effects of ATR were observed at levels that were not toxic to the tissue, as LDH release into the medium (lactate dehydrogenase, an index of non-specific cytotoxicity) was not affected by ATR." | 1.34 | Dopaminergic toxicity of the herbicide atrazine in rat striatal slices. ( Carr, RL; Filipov, NM; Sistrunk, SC; Stewart, MA, 2007) |
| "Homovanillic acid (HVA) is a metabolite of dopamine, reflecting central dopamine metabolism, primarily situated in the striatum." | 1.32 | Decreased homovanillic acid concentrations in cerebrospinal fluid in children without a known defect in dopamine metabolism. ( Rotteveel, JJ; Van Der Heyden, JC; Wevers, RA, 2003) |
| "In the group of 9 children with other psychoses, both the level of homovanillic acid and that of 5-hydroxy-indoleacetic acid was raised." | 1.27 | Childhood psychosis and monoamine metabolites in spinal fluid. ( Gillberg, C; Hamilton-Hellberg, C; Svennerholm, L, 1983) |
| "Of five comatose patients, two had cerebrovascular lesions and three had sustained head injury, and, in four of the five, the values of either one or both of HVA and 5-HIAA were low, but in the fifth case the 5-HIAA value was high." | 1.26 | Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus. ( Inagawa, T; Ishikawa, S; Uozumi, T, 1980) |
| "The subjects with encephalopathy had raised plasma free tryptophan, CSF tryptophan, and CSF 5-hydroxyindoleacetic acid." | 1.26 | Cerebral transmitter precursors and metabolites in advanced renal disease. ( Callaghan, N; Curzon, G; Kantamaneni, BD; Murnaghan, D; Sullivan, PA, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (63.89) | 18.7374 |
| 1990's | 7 (19.44) | 18.2507 |
| 2000's | 5 (13.89) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Winter, C | 1 |
| Djodari-Irani, A | 1 |
| Sohr, R | 1 |
| Morgenstern, R | 1 |
| Feldon, J | 1 |
| Juckel, G | 1 |
| Meyer, U | 1 |
| Willemsen, MA | 1 |
| Verbeek, MM | 1 |
| Kamsteeg, EJ | 1 |
| de Rijk-van Andel, JF | 1 |
| Aeby, A | 1 |
| Blau, N | 1 |
| Burlina, A | 1 |
| Donati, MA | 1 |
| Geurtz, B | 1 |
| Grattan-Smith, PJ | 1 |
| Haeussler, M | 1 |
| Hoffmann, GF | 1 |
| Jung, H | 1 |
| de Klerk, JB | 1 |
| van der Knaap, MS | 1 |
| Kok, F | 1 |
| Leuzzi, V | 1 |
| de Lonlay, P | 1 |
| Megarbane, A | 1 |
| Monaghan, H | 1 |
| Renier, WO | 1 |
| Rondot, P | 1 |
| Ryan, MM | 1 |
| Seeger, J | 1 |
| Smeitink, JA | 1 |
| Steenbergen-Spanjers, GC | 1 |
| Wassmer, E | 1 |
| Weschke, B | 1 |
| Wijburg, FA | 1 |
| Wilcken, B | 1 |
| Zafeiriou, DI | 1 |
| Wevers, RA | 2 |
| Van Der Heyden, JC | 1 |
| Rotteveel, JJ | 1 |
| Moroz, IA | 1 |
| Peciña, S | 1 |
| Schallert, T | 1 |
| Stewart, J | 1 |
| Filipov, NM | 1 |
| Stewart, MA | 1 |
| Carr, RL | 1 |
| Sistrunk, SC | 1 |
| Inagawa, T | 1 |
| Ishikawa, S | 1 |
| Uozumi, T | 1 |
| Yamamoto, M | 1 |
| Otsuki, S | 1 |
| Miyake, K | 1 |
| Namba, R | 1 |
| Gillberg, C | 1 |
| Svennerholm, L | 1 |
| Hamilton-Hellberg, C | 1 |
| Melamed, E | 1 |
| Hefti, F | 1 |
| Bird, ED | 1 |
| Arias, J | 1 |
| Alsasua, A | 1 |
| Estebánez, E | 1 |
| López, ML | 1 |
| Arias, JI | 1 |
| Durán, M | 1 |
| García de Jalón, PD | 1 |
| Durán Sacristán, H | 1 |
| Gil-Nagel, A | 1 |
| Morlán, L | 1 |
| Balseiro, J | 1 |
| García de Yébenes, J | 1 |
| Cabello, A | 1 |
| Martínez-Martín, P | 1 |
| Hossain, MA | 1 |
| Weiner, N | 1 |
| Xia, XG | 1 |
| Schmidt, N | 1 |
| Teismann, P | 1 |
| Ferger, B | 1 |
| Schulz, JB | 1 |
| Sullivan, PA | 1 |
| Murnaghan, D | 1 |
| Callaghan, N | 1 |
| Kantamaneni, BD | 2 |
| Curzon, G | 2 |
| Passouant, P | 1 |
| Billiard, M | 1 |
| Besset, A | 1 |
| Renaud, B | 1 |
| Moskowitz, MA | 1 |
| Wurtman, RJ | 1 |
| Rimón, R | 1 |
| Roos, BE | 2 |
| Kampman, R | 1 |
| Hyyppä, S | 1 |
| Ranta, P | 1 |
| Myllylä, V | 1 |
| Rosenberg, RN | 2 |
| Nyhan, WL | 2 |
| Bay, C | 2 |
| Shore, P | 1 |
| Michel, D | 1 |
| Tommasi, M | 1 |
| Laurent, B | 1 |
| Trillet, M | 1 |
| Schott, B | 1 |
| Bridges, PK | 1 |
| Bartlett, JR | 1 |
| Sepping, P | 1 |
| Siever, L | 1 |
| Kraemer, H | 1 |
| Sack, R | 1 |
| Angwin, P | 1 |
| Berger, P | 1 |
| Zarcone, V | 1 |
| Barchas, J | 1 |
| Brodie, HK | 1 |
| Amin, F | 1 |
| Davidson, M | 1 |
| Davis, KL | 1 |
| Gordon, K | 1 |
| Statman, D | 1 |
| Johnston, MV | 2 |
| Robinson, TE | 2 |
| Becker, JB | 1 |
| Silverstein, FS | 2 |
| Degrell, I | 1 |
| Nagy, E | 1 |
| Castañeda, E | 1 |
| Whishaw, IQ | 1 |
| Riley, DE | 1 |
| Lang, AE | 1 |
| Lewis, A | 1 |
| Resch, L | 1 |
| Ashby, P | 1 |
| Hornykiewicz, O | 2 |
| Black, S | 1 |
| Kish, SJ | 1 |
| Gilbert, JJ | 1 |
| Chang, LJ | 1 |
| Mirchandani, L | 1 |
| Shannak, K | 1 |
| Bradbury, AJ | 1 |
| Costall, B | 1 |
| Domeney, AM | 1 |
| Testa, B | 1 |
| Jenner, PG | 1 |
| Marsden, CD | 1 |
| Naylor, RJ | 1 |
| Nakamura, S | 1 |
| Greenberg, H | 1 |
| Knutsen, CA | 1 |
| Chandler, W | 1 |
| Phillips, T | 1 |
| Ensminger, WD | 1 |
| Scheinin, M | 1 |
| Fibiger, HC | 1 |
| LePiane, FG | 1 |
| Jakubovic, A | 1 |
| Phillips, AG | 1 |
| Lakke, JP | 1 |
| Korf, J | 1 |
| van Praag, HM | 1 |
| Minderhoud, JM | 1 |
| Schut, T | 1 |
| Garelis, E | 1 |
| Sourkes, TL | 1 |
| Lycke, E | 1 |
3 reviews available for homovanillic acid and Brain Diseases
| Article | Year |
|---|---|
Catecholamines and neurologic diseases (second of two parts).
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Brain Diseases; Catecholamines; Cereb | 1975 |
Homovanillic acid measurement in clinical research: a review of methodology.
Topics: Body Fluids; Brain Diseases; Female; Homovanillic Acid; Humans; Male; Schizophrenia | 1992 |
Monoamine metabolites in human cerebrospinal fluid: indicators of neuronal activity?
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Biogenic Amines; Brain Diseases; Glycols; Homo | 1985 |
33 other studies available for homovanillic acid and Brain Diseases
| Article | Year |
|---|---|
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Press | 2009 |
Tyrosine hydroxylase deficiency: a treatable disorder of brain catecholamine biosynthesis.
Topics: Age of Onset; Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases; Catecholamines; Child, Pr | 2010 |
Decreased homovanillic acid concentrations in cerebrospinal fluid in children without a known defect in dopamine metabolism.
Topics: Adolescent; Age Factors; Brain Diseases; Child; Child, Preschool; Dopamine; Homovanillic Acid; Human | 2003 |
Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behav | 2004 |
Dopaminergic toxicity of the herbicide atrazine in rat striatal slices.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atrazine; Brain Diseases; Corpus Striatum; Dopamine; Dopami | 2007 |
Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus.
Topics: Adolescent; Adult; Brain Diseases; Brain Neoplasms; Child; Coma; Craniopharyngioma; Ependymoma; Fema | 1980 |
[Lumbar cerebrospinal fluid levels of GABA, HVA and 5HIAA in various patients with choreic movement and effects with isoniazid treatment].
Topics: Acanthocytes; Adult; Aged; Atrophy; Brain Diseases; Chorea; gamma-Aminobutyric Acid; Homovanillic Ac | 1983 |
Childhood psychosis and monoamine metabolites in spinal fluid.
Topics: Adolescent; Age Factors; Autistic Disorder; Brain Diseases; Cerebral Palsy; Child; Child, Preschool; | 1983 |
Huntington chorea is not associated with hyperactivity of nigrostriatal dopaminergic neurons: studies in postmortem tissues and in rats with kainic acid lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Dopamine; Female; Homovani | 1982 |
[Experimental portosystemic encephalopathy: values of noradrenaline, dopamine, and homovanillic acid in the CNS of rats at 15, 30 and 60 days after terminolateral porto-caval anastomosis].
Topics: Animals; Brain Chemistry; Brain Diseases; Dopamine; Homovanillic Acid; Male; Norepinephrine; Phenyla | 1982 |
[Neuro-acanthocytosis with associated myopathy. A case report].
Topics: Acanthocytes; Adult; Basal Ganglia; Basophils; Brain Diseases; Cerebellum; Denervation; Homovanillic | 1994 |
Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biopterins; Brain Diseases; Carbidopa; Corpus Striatum; Cyc | 1993 |
Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Benzazepines; Brain Diseases; Carbido | 2001 |
Cerebral transmitter precursors and metabolites in advanced renal disease.
Topics: Adult; Aged; Brain; Brain Diseases; Fatty Acids, Nonesterified; Female; Homovanillic Acid; Humans; H | 1978 |
Encephalopathy associated with bismuth salt ingestion and brain monoamines.
Topics: Adult; Aged; Bismuth; Brain Diseases; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; M | 1979 |
Monoamine metabolite levels in cerebrospinal fluid and brain atrophy in lobotomized schizophrenic patients.
Topics: Atrophy; Brain Diseases; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; | 1979 |
Autosomal dominant striatonigral degeneration. A clinical, pathologic, and biochemical study of a new genetic disorder.
Topics: Adult; Aged; Brain Diseases; Caudate Nucleus; Cerebellar Nuclei; Corpus Striatum; Eye Movements; Fem | 1976 |
[Striato-nigral degeneration. A propos of 2 anatomo-clinical cases].
Topics: Brain Diseases; Corpus Striatum; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; | 1976 |
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanilli | 1976 |
Autosomal dominant striatonigral degeneration: a clinical, pathological, and biochemical study of a new genetic disorder.
Topics: Adult; Brain Diseases; Corpus Striatum; Dopamine; Female; Genes, Dominant; Homovanillic Acid; Humans | 1976 |
Gradients of biogenic amine metabolites in cerebrospinal fluid.
Topics: Alzheimer Disease; Amphetamine; Brain Diseases; Brain Neoplasms; Depression; Homovanillic Acid; Huma | 1975 |
Transient hypoxia alters striatal catecholamine metabolism in immature brain: an in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Diseases; Corpus Striatum; Dialysis | 1990 |
Correlations between cisternal CSF and plasma concentrations of HVA, MHPG, 5-HIAA, DA, and NA.
Topics: Adult; Aged; Aged, 80 and over; Blood-Brain Barrier; Brain; Brain Diseases; Dopamine; Female; Glycol | 1990 |
Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain Diseases; Corpus Striatum; Dialysis; Dop | 1990 |
Cortical-basal ganglionic degeneration.
Topics: Aged; Autopsy; Basal Ganglia; Basal Ganglia Diseases; Brain Chemistry; Brain Diseases; Cerebral Cort | 1990 |
Brain neurotransmitter abnormalities in neuronal intranuclear inclusion body disorder.
Topics: Adolescent; Brain; Brain Diseases; Dopamine; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Hum | 1985 |
The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic | 1985 |
[Neurotransmitters and degenerative diseases in the central nervous system].
Topics: Acetylcholinesterase; Aged; Aging; Brain Diseases; Dementia; Dopamine; Homovanillic Acid; Humans; Hy | 1986 |
Effects of intraventricular methotrexate on cerebrospinal fluid monoamine metabolites in rhesus monkeys.
Topics: Animals; Brain Diseases; Cerebral Ventricles; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; | 1986 |
The role of dopamine in intracranial self-stimulation of the ventral tegmental area.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Dopamine; Electric Stimula | 1987 |
Clinical significance of probenecid test.
Topics: Brain Diseases; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Parkinson Disease; Phenylacetat | 1973 |
Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man.
Topics: Adolescent; Adult; Brain Diseases; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovani | 1974 |
Viral infections in the central nervous system and 5-hydroxytryptamine metabolism.
Topics: Animals; Brain; Brain Diseases; Catecholamines; Coxsackievirus Infections; Dopamine; Encephalitis; H | 1974 |