homovanillic acid has been researched along with Basal Ganglia Diseases in 33 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The introduction of the atypical neuroleptic, clozapine, has had widespread influence not only on the treatment of the seriously mentally ill patient, but also on new drug development and on hypotheses of the pathophysiology of schizophrenia." | 9.07 | Predictors of clozapine response in schizophrenia. ( Hsiao, JK; Litman, RE; Owen, RR; Pickar, D; Su, TP, 1994) |
| "The level of homovanillic acid (HVA) in the cerebrospinal fluid (CSF) as an indicator of the cerebral metabolism of dopamine was examined prior to and after the stereotaxic operation on the basal ganglia in 13 patients with extrapyramidal hyperkinetic syndromes." | 7.67 | [Homovanillic acid content in the cerebrospinal fluid as an index of dopamine cerebral metabolism before and after a stereotaxic operation in patients with extrapyramidal hyperkinetic syndromes]. ( Barkhatova, VP; Demina, EG; Kandel', EI; Omorova, TM, 1984) |
| "The introduction of the atypical neuroleptic, clozapine, has had widespread influence not only on the treatment of the seriously mentally ill patient, but also on new drug development and on hypotheses of the pathophysiology of schizophrenia." | 5.07 | Predictors of clozapine response in schizophrenia. ( Hsiao, JK; Litman, RE; Owen, RR; Pickar, D; Su, TP, 1994) |
| "The level of homovanillic acid (HVA) in the cerebrospinal fluid (CSF) as an indicator of the cerebral metabolism of dopamine was examined prior to and after the stereotaxic operation on the basal ganglia in 13 patients with extrapyramidal hyperkinetic syndromes." | 3.67 | [Homovanillic acid content in the cerebrospinal fluid as an index of dopamine cerebral metabolism before and after a stereotaxic operation in patients with extrapyramidal hyperkinetic syndromes]. ( Barkhatova, VP; Demina, EG; Kandel', EI; Omorova, TM, 1984) |
| "Patients with the Lewy body variant of Alzheimer's disease tended to experience more frequent extrapyramidal side effects of neuroleptics than did the patients with Alzheimer's disease, but for patients in the two groups who were not exposed to neuroleptics, there was little difference in frequency of extrapyramidal side effects." | 1.29 | Alzheimer's disease and its Lewy body variant: a clinical analysis of postmortem verified cases. ( Cullum, CM; Honig, L; Risser, RC; Rosenberg, RN; Speciale, S; Weiner, MF; White, C, 1996) |
| " The results support the hypothesis of a positive correlation between the CSF HVA and the hypokinetic-rigid side effect and a negative correlation between the pretherapeutic dopamine turnover and the risk of neuroleptic Parkinsonism." | 1.27 | Hypokinetic-rigid extrapyramidal side effects of neuroleptics: the relationship of the silent period in EMG and HVA and 5-HIAA in CSF. ( Baslo, A; Eroğlu, L; Hizal, A; Yazici, J; Yazici, O, 1986) |
| "Patients with Huntington's chorea showed a low level of the HVA in the intraventricular fluid." | 1.26 | [Approaches to the study of dopamine metabolism in various extrapyramidal diseases]. ( Barkhatova, VP; Demina, EG; Kandel', EI, 1981) |
| "The effect of various antipsychotic drugs on the blockade of dopaminergic receptors in striatum and limbic forebrain was examined by establishing dose-response curves for the increase in HVA and for the antagonism of d-amphetamine-induced rotation in rats with unilateral lesions of the substantia nigra." | 1.25 | On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain. ( Dingell, JV; Hill, H; Robinson, SE; Setler, P; Stawarz, RJ; Sulser, F, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (66.67) | 18.7374 |
| 1990's | 7 (21.21) | 18.2507 |
| 2000's | 3 (9.09) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ota, T | 1 |
| Miura, I | 1 |
| Kanno-Nozaki, K | 1 |
| Hoshino, H | 1 |
| Horikoshi, S | 1 |
| Fujimori, H | 1 |
| Kanno, T | 1 |
| Mashiko, H | 1 |
| Yabe, H | 1 |
| Kaneda, Y | 1 |
| Ohmori, T | 1 |
| Kakihara, S | 1 |
| Yoshimura, R | 1 |
| Shinkai, K | 1 |
| Matsumoto, C | 1 |
| Goto, M | 1 |
| Kaji, K | 1 |
| Yamada, Y | 1 |
| Ueda, N | 1 |
| Ohmori, O | 1 |
| Nakamura, J | 1 |
| Bowers, MB | 1 |
| Cramer, H | 1 |
| Warter, JM | 1 |
| Renaud, B | 1 |
| Tollefson, GD | 1 |
| Garvey, MJ | 1 |
| Barkhatova, VP | 3 |
| Kandel', EI | 2 |
| Omorova, TM | 1 |
| Demina, EG | 2 |
| Pickar, D | 1 |
| Owen, RR | 1 |
| Litman, RE | 1 |
| Hsiao, JK | 1 |
| Su, TP | 1 |
| Wolkin, A | 1 |
| Duncan, E | 1 |
| Sanfilipo, M | 1 |
| Wieland, S | 1 |
| Cooper, TB | 1 |
| Rotrosen, J | 1 |
| Deutch, AY | 1 |
| Lewis, DA | 1 |
| Whitehead, RE | 1 |
| Elsworth, JD | 1 |
| Iadarola, MJ | 1 |
| Redmond, DE | 1 |
| Roth, RH | 1 |
| Weiner, MF | 1 |
| Risser, RC | 1 |
| Cullum, CM | 1 |
| Honig, L | 1 |
| White, C | 1 |
| Speciale, S | 1 |
| Rosenberg, RN | 1 |
| Haley, RW | 1 |
| Fleckenstein, JL | 1 |
| Marshall, WW | 1 |
| McDonald, GG | 1 |
| Kramer, GL | 1 |
| Petty, F | 1 |
| Sayers, AC | 1 |
| Bürki, HR | 1 |
| Ruch, W | 1 |
| Asper, H | 1 |
| Larskiĭ, EG | 1 |
| Stawarz, RJ | 1 |
| Hill, H | 1 |
| Robinson, SE | 1 |
| Setler, P | 1 |
| Dingell, JV | 1 |
| Sulser, F | 1 |
| Poirier, L | 1 |
| Filion, M | 1 |
| Langelier, P | 1 |
| Larochelle, L | 1 |
| Poirier, LJ | 1 |
| Parent, A | 1 |
| Roberge, AG | 1 |
| Messiha, FS | 1 |
| Larson, JW | 1 |
| Van Praag, HM | 1 |
| Korf, J | 1 |
| Gerlach, J | 1 |
| Thorsen, K | 1 |
| Fog, R | 1 |
| Komatsu, H | 1 |
| Nishimura, A | 1 |
| Okano, S | 1 |
| Miyanomae, Y | 1 |
| Takeuchi, Y | 1 |
| Sawada, T | 1 |
| Soininen, H | 1 |
| Laulumaa, V | 1 |
| Helkala, EL | 1 |
| Hartikainen, P | 1 |
| Riekkinen, PJ | 1 |
| Riley, DE | 1 |
| Lang, AE | 1 |
| Lewis, A | 1 |
| Resch, L | 1 |
| Ashby, P | 1 |
| Hornykiewicz, O | 2 |
| Black, S | 1 |
| Kish, SJ | 1 |
| Chang, LJ | 1 |
| Mirchandani, L | 1 |
| Shannak, K | 1 |
| Yazici, O | 1 |
| Hizal, A | 1 |
| Eroğlu, L | 1 |
| Baslo, A | 1 |
| Yazici, J | 1 |
| Sheng, JG | 1 |
| Xu, DL | 1 |
| Yu, HZ | 1 |
| Xu, XR | 1 |
| Tang, QM | 1 |
| Waldmeier, PC | 1 |
| Huber, H | 1 |
| Heinrich, M | 1 |
| Stoecklin, K | 1 |
| Smiałek, M | 1 |
| Królikiewicz-Sciborowska, H | 1 |
| Skrobisz, MD | 1 |
| Niemczewska-Syropolska, M | 1 |
| Sasinowska, M | 1 |
| Verhoeven, WM | 1 |
| Elderson, A | 1 |
| Westenberg, HG | 1 |
| Chase, TN | 1 |
| Matthysse, S | 1 |
| Eben, E | 1 |
| Ackenheil, M | 1 |
| Raese, J | 1 |
| Rüther, E | 1 |
3 reviews available for homovanillic acid and Basal Ganglia Diseases
| Article | Year |
|---|---|
Brain nervous mechanisms involved in the so-called extra pyramidal motor and psychomotor disturbances.
Topics: Animals; Athetosis; Basal Ganglia Diseases; Brain; Brain Stem; Cats; Corpus Striatum; Disease Models | 1975 |
The striopallidal system: Its implication in motor disorders.
Topics: Animals; Basal Ganglia Diseases; Cats; Corpus Striatum; Disease Models, Animal; Dopamine; Extrapyram | 1975 |
Antipsychotic drug actions: a clue to the neuropathology of schizophrenia?
Topics: Animals; Basal Ganglia Diseases; Brain; Butyrophenones; Cognition; Dogs; Dopamine; Haplorhini; Homov | 1973 |
4 trials available for homovanillic acid and Basal Ganglia Diseases
| Article | Year |
|---|---|
Effects of Shakuyaku-Kanzo-to on Extrapyramidal Symptoms During Antipsychotic Treatment: A Randomized, Open-Label Study.
Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; | 2015 |
Impact of risperidone medication on quality of life and gonadal axis hormones in schizophrenia male patients with acute exacerbation.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Gonadal Steroid Hormones; Homovanillic Acid; Hu | 2003 |
Predictors of clozapine response in schizophrenia.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Double-Blind Method; Female; Fluphen | 1994 |
Extrapyramidal reactions and amine metabolites in cerebrospinal fluid during haloperidol and clozapine treatment of schizophrenic patients.
Topics: Adult; Aged; Basal Ganglia Diseases; Clinical Trials as Topic; Clozapine; Dibenzazepines; Haloperido | 1975 |
26 other studies available for homovanillic acid and Basal Ganglia Diseases
| Article | Year |
|---|---|
Prediction of response to risperidone treatment with respect to plasma concencentrations of risperidone, catecholamine metabolites, and polymorphism of cytochrome P450 2D6.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Caffeine; Catecholamines; Cen | 2005 |
Family history and CSF homovanillic acid pattern during neuroleptic treatment.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Female; Homovanillic Acid; Hospitalization; Hos | 1984 |
Analysis of neurotransmitter metabolites and adenosine 3',5'-monophosphate in the CSF of patients with extrapyramidal motor disorders.
Topics: Adult; Basal Ganglia Diseases; Cyclic AMP; Female; Homovanillic Acid; Humans; Huntington Disease; Hy | 1984 |
The neuroleptic syndrome and central dopamine metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Antipsychotic Agents; Basal Ganglia Diseases; Dopamine; Female; Homo | 1984 |
[Homovanillic acid content in the cerebrospinal fluid as an index of dopamine cerebral metabolism before and after a stereotaxic operation in patients with extrapyramidal hyperkinetic syndromes].
Topics: Adolescent; Adult; Basal Ganglia; Basal Ganglia Diseases; Brain; Cryosurgery; Dopamine; Female; Homo | 1984 |
[Approaches to the study of dopamine metabolism in various extrapyramidal diseases].
Topics: Athetosis; Basal Ganglia Diseases; Chorea; Dopamine; Dystonia Musculorum Deformans; Homovanillic Aci | 1981 |
Persistent psychosis after reduction in pre- and post-synaptic dopaminergic function.
Topics: Adult; alpha-Methyltyrosine; Antipsychotic Agents; Basal Ganglia Diseases; Dopamine; Drug Resistance | 1994 |
Effects of D2 dopamine receptor antagonists on Fos protein expression in the striatal complex and entorhinal cortex of the nonhuman primate.
Topics: Animals; Basal Ganglia Diseases; Caudate Nucleus; Chlorocebus aethiops; Dopamine Antagonists; Dopami | 1996 |
Alzheimer's disease and its Lewy body variant: a clinical analysis of postmortem verified cases.
Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Basal Ganglia Diseases; Body Height; Delusions; Diagn | 1996 |
Effect of basal ganglia injury on central dopamine activity in Gulf War syndrome: correlation of proton magnetic resonance spectroscopy and plasma homovanillic acid levels.
Topics: Basal Ganglia Diseases; Brain; Chromatography, High Pressure Liquid; Diagnosis, Differential; Dopami | 2000 |
Anticholinergic properties of antipsychotic drugs and their relation to extrapyramidal side-effects.
Topics: Animals; Antipsychotic Agents; Atropine; Basal Ganglia Diseases; Clozapine; Corpus Striatum; Drug In | 1976 |
[Value of homovanillic acid determination in ventricular cerebrospinal fluid to assess brain dopamine metabolism in several extrapyramidal diseases].
Topics: Basal Ganglia Diseases; Homovanillic Acid; Humans; Phenylacetates | 1979 |
On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Clozapine; Corpus Striatum; D | 1975 |
Biochemical changes associated with drug-produced alterations in motor function and the psyche: a possible underlying mechanism.
Topics: Adult; Basal Ganglia Diseases; Cannabis; Chlorpromazine; Dopamine; Homovanillic Acid; Humans; Lyserg | 1977 |
Importance of dopamine metabolism for clinical effects and side effects of neuroleptics.
Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Chlorpromazine; Dopamine; Dopamine Antago | 1976 |
Neuroleptic malignant syndrome-like state in a patient with Down syndrome and basal ganglia calcification.
Topics: Adolescent; Basal Ganglia Diseases; Calcinosis; Down Syndrome; Homovanillic Acid; Humans; Hydroxyind | 1992 |
Extrapyramidal signs in Alzheimer's disease: a 3-year follow-up study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Basal Ganglia Diseases; Dopamine; | 1992 |
Cortical-basal ganglionic degeneration.
Topics: Aged; Autopsy; Basal Ganglia; Basal Ganglia Diseases; Brain Chemistry; Brain Diseases; Cerebral Cort | 1990 |
Progressive supranuclear palsy: relationship between extrapyramidal disturbances, dementia, and brain neurotransmitter markers.
Topics: Aged; Aspartic Acid; Basal Ganglia Diseases; Brain; Bulbar Palsy, Progressive; Choline O-Acetyltrans | 1985 |
Hypokinetic-rigid extrapyramidal side effects of neuroleptics: the relationship of the silent period in EMG and HVA and 5-HIAA in CSF.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Electric Stimulation; Electromyography; Haloperidol; H | 1986 |
Partial protection from the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by Pro-Leu-Gly-NH2(PLG; MIF-1).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia | 1987 |
Discrimination of neuroleptics by means of their interaction with amfonelic acid: an attempt to characterize the test.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Corpus Striat | 1985 |
[Homovanillic acid (HVA) and gamma-aminobutyric acid (GABA) levels in the cerebrospinal fluid of patients with extrapyramidal syndromes].
Topics: Adult; Age Factors; Aged; Basal Ganglia Diseases; Female; gamma-Aminobutyric Acid; Homovanillic Acid | 1986 |
Neuroleptic malignant syndrome: successful treatment with bromocriptine.
Topics: Adolescent; Basal Ganglia Diseases; Bromocriptine; Creatine Kinase; Haloperidol; Homovanillic Acid; | 1985 |
Central monoamine metabolism in man. Effect of putative dopamine receptor agonists and antagonists.
Topics: Adult; Basal Ganglia Diseases; Brain; Central Nervous System Diseases; Dopamine; Haloperidol; Homova | 1973 |
[Biochemical mechanisms of extrapyramidal-motoric effect of haloperidol in man].
Topics: Adult; Basal Ganglia Diseases; Female; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic A | 1974 |