homovanillic acid has been researched along with Aura in 40 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 7.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| "The concentration of dopamine (DA) metabolite-homovanillic acid (HVA) in cerebrospinal fluid (CSF) of 40 patients with schizophrenia 27 with epilepsy and 15 controls without disorders of CNS was reported." | 3.70 | [Study on dopamine metabolite in cerebrospinal fluid of schizophrenics and epilepsics]. ( Chen, X; Jiang, S; Liao, W, 1998) |
| " Vigabatrin, 50 mg kg-1, was administered orally as add-on therapy to 11 patients with drug-resistant complex partial epilepsy as a single dose, then once every third day for 2 months, every other day for 2 months and daily for 1 month." | 3.67 | The effect of different vigabatrin treatment regimens on CSF biochemistry and seizure control in epileptic patients. ( Ben-Menachem, E; Dahlgren, L; Haegele, KD; Hardenberg, J; Huebert, N; Mumford, JP; Persson, LI; Schechter, PJ, 1989) |
| "Maturation of monoamine neuronal systems was studied by measuring cerebrospinal fluid metabolites of dopamine (homovanillic acid) and serotonin (5-hydroxyindoleacetic acid) in 38 children with epilepsy and other neurological disorders, to whom probenecid had previously been administered." | 3.66 | Ontogeny of dopamine and serotonin metabolites in the cerebrospinal fluid of children with neurological disorders. ( Bowers, MB; Cohen, DJ; Leckman, JF; Shaywitz, BA; Young, JG, 1980) |
| "To assess the possible role of amine neurotransmitters in human epilepsy, we measured metabolites of serotonin (5-hydroxyindoleacetic acid [5-HIAA]), dopamine (homovanillic acid [HVA]), and norepinephrine (3-methoxy-4-hydroxyphenylethylene glycol [MHPG]) in the lumbar cerebrospinal fluid (CSF) of patients with partial complex seizures and in neurologic controls." | 3.66 | Monoamine metabolites in the CSF of epileptic patients. ( Fang, TY; Gauthier, SG; Laxer, KD; Missala, K; Sourkes, TL; Young, SN, 1979) |
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 3.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| "In 6 patients with intention myoclonus, the cerebrospinal fluid concentration of 5-hydroxyindoleacetic acid, a metabolite of serotonin was found to be significantly decreased." | 2.64 | Serotonin and myoclonus. ( Bowers, MB; Jutkowitz, R; Rosenbaum, D; Van Woert, MH, 1976) |
| "The 18 patients had either West syndrome (12 patients) or Lennox-Gastaut syndrome (6 patients), which was intractable to antiepileptic drug therapy and to adrenocorticotrophic hormone." | 1.29 | Thyrotropin-releasing hormone in treatment of intractable epilepsy: neurochemical analysis of CSF monoamine metabolites. ( Kawase, S; Matsuo, S; Mitsufuji, N; Nishimura, A; Sawada, T; Takeuchi, Y; Tominaga, M; Yamazoe, I, 1995) |
| "The Rett syndrome is a progressive disorder in female patients that is characterized by autistic behavior, dementia, ataxia, loss of purposeful use of the hands, and seizures." | 1.27 | Reduction of biogenic amine levels in the Rett syndrome. ( Butler, IJ; Glaze, DG; Percy, AK; Riccardi, VM; Zoghbi, HY, 1985) |
| "Transient hyperkinesia was observed in a 16-year-old epileptic and mentally retarded patient after a single intravenous perfusion of diphenylhydantoin (DPH)." | 1.26 | Transient hyperkinesia after a single intravenous perfusion of diphenylhydantoin. Report of a case associated with nontoxic plasma levels of diphenylhydantoin. ( Courjon, J; Dalery, J; de Villard, R; Mauguière, F, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (67.50) | 18.7374 |
| 1990's | 8 (20.00) | 18.2507 |
| 2000's | 4 (10.00) | 29.6817 |
| 2010's | 1 (2.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horvath, GA | 1 |
| Demos, M | 1 |
| Shyr, C | 1 |
| Matthews, A | 1 |
| Zhang, L | 1 |
| Race, S | 1 |
| Stockler-Ipsiroglu, S | 1 |
| Van Allen, MI | 1 |
| Mancarci, O | 1 |
| Toker, L | 1 |
| Pavlidis, P | 1 |
| Ross, CJ | 1 |
| Wasserman, WW | 1 |
| Trump, N | 1 |
| Heales, S | 2 |
| Pope, S | 1 |
| Cross, JH | 1 |
| van Karnebeek, CD | 1 |
| Crawley, F | 1 |
| Rudge, P | 1 |
| Chanut, E | 1 |
| Labarthe, B | 1 |
| Lacroix, B | 1 |
| Noda, A | 1 |
| Gasdeblay, S | 1 |
| Bondier, JR | 1 |
| Versaux-Botteri, C | 1 |
| García-Cazorla, A | 1 |
| Serrano, M | 1 |
| Pérez-Dueñas, B | 1 |
| González, V | 1 |
| Ormazábal, A | 2 |
| Pineda, M | 1 |
| Fernández-Alvarez, E | 1 |
| Campistol, JM | 1 |
| Artuch, RM | 1 |
| Ruiz, A | 1 |
| García-Villoria, J | 1 |
| Zschocke, J | 1 |
| Fiol, M | 1 |
| Navarro-Sastre, A | 1 |
| Artuch, R | 1 |
| Vilaseca, MA | 1 |
| Ribes, A | 1 |
| Shaywitz, BA | 4 |
| Cohen, DJ | 3 |
| Leckman, JF | 1 |
| Young, JG | 1 |
| Bowers, MB | 3 |
| Mohan, A | 1 |
| Nag, D | 1 |
| Misra, RN | 1 |
| Gujrati, VR | 1 |
| Shanker, K | 1 |
| Doval, DC | 1 |
| Saxena, RC | 1 |
| Bhargava, KP | 1 |
| Baliga, L | 1 |
| Rao, A | 1 |
| Raja, A | 1 |
| Rao, SN | 1 |
| Anderson, GM | 1 |
| Novotny, EJ | 1 |
| Ebersole, JS | 1 |
| Sullivan, CM | 1 |
| Gillespie, SM | 1 |
| Takeuchi, Y | 1 |
| Tominaga, M | 1 |
| Mitsufuji, N | 1 |
| Yamazoe, I | 1 |
| Kawase, S | 1 |
| Nishimura, A | 1 |
| Matsuo, S | 1 |
| Sawada, T | 1 |
| Kobayashi, K | 4 |
| Kawashima, K | 1 |
| Kawashima, Y | 1 |
| Yamamura, T | 1 |
| Kuse, H | 1 |
| Asano, Y | 1 |
| Kawai, Y | 1 |
| Hori, M | 1 |
| Okaniwa, A | 1 |
| Serikawa, T | 1 |
| Jiang, S | 1 |
| Chen, X | 1 |
| Liao, W | 1 |
| Laxer, KD | 1 |
| Sourkes, TL | 1 |
| Fang, TY | 1 |
| Young, SN | 2 |
| Gauthier, SG | 1 |
| Missala, K | 1 |
| Chadwick, D | 4 |
| Jenner, P | 4 |
| Reynolds, EH | 4 |
| Nagao, T | 1 |
| Fujimoto, A | 1 |
| Ohshimo, T | 1 |
| Yamamoto, M | 1 |
| Kugoh, T | 1 |
| Akiyama, K | 1 |
| Otsuki, S | 1 |
| Carrieri, P | 1 |
| Orefice, G | 1 |
| Mandarini, A | 1 |
| Rossi, V | 1 |
| Campanella, G | 1 |
| Koide, Y | 1 |
| Doi, T | 1 |
| Kohsaka, M | 1 |
| Hosokawa, K | 2 |
| Oku, Y | 2 |
| Mori, A | 3 |
| Mauguière, F | 1 |
| Dalery, J | 1 |
| de Villard, R | 1 |
| Courjon, J | 1 |
| Mantovani, J | 1 |
| DeVivo, DC | 1 |
| Trimble, M | 1 |
| Driver, MV | 1 |
| Kariya, T | 1 |
| Van Woert, MH | 1 |
| Jutkowitz, R | 1 |
| Rosenbaum, D | 1 |
| Ebara, Y | 1 |
| Livrea, P | 1 |
| Di Reda, L | 1 |
| Puca, FM | 1 |
| Genco, S | 1 |
| Specchio, L | 1 |
| Papagno, G | 1 |
| Chanarin, I | 1 |
| Kabuto, H | 1 |
| Yokoi, I | 1 |
| Abed, WT | 1 |
| Botez, MI | 1 |
| Bonuccelli, U | 1 |
| Garant, D | 1 |
| Fariello, R | 1 |
| Zoghbi, HY | 1 |
| Percy, AK | 1 |
| Glaze, DG | 1 |
| Butler, IJ | 1 |
| Riccardi, VM | 1 |
| Lloyd, KG | 1 |
| Scatton, B | 1 |
| Voltz, C | 1 |
| Bryere, P | 1 |
| Valin, A | 1 |
| Naquet, R | 1 |
| Ben-Menachem, E | 1 |
| Persson, LI | 1 |
| Schechter, PJ | 1 |
| Haegele, KD | 1 |
| Huebert, N | 1 |
| Hardenberg, J | 1 |
| Dahlgren, L | 1 |
| Mumford, JP | 1 |
| Louw, D | 1 |
| Sutherland, GR | 1 |
| Glavin, GB | 1 |
| Girvin, J | 1 |
| Kimiya, S | 1 |
| Seki, T | 1 |
| Maezawa, M | 1 |
| Yamada, T | 1 |
| Tachibana, Y | 1 |
| Klimowicz-Młodzik, I | 1 |
| Pisarski, W | 1 |
| Sasinowska, M | 1 |
| Smiałek, M | 1 |
| Johnson, WT | 1 |
| Bowers, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00004325] | 200 participants | Observational | 1988-12-31 | Completed | |||
| The Effect of Vigabatrin on Cerebral Blood Flow and Glucose Metabolism[NCT00001489] | 20 participants | Observational | 1994-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for homovanillic acid and Aura
| Article | Year |
|---|---|
Brain monoamines in seizure mechanism (review).
Topics: Animals; Brain; Carbonic Anhydrase Inhibitors; Catecholamines; Child; Dextroamphetamine; Dopamine; E | 1977 |
3 trials available for homovanillic acid and Aura
| Article | Year |
|---|---|
Aspartame has no effect on seizures or epileptiform discharges in epileptic children.
Topics: Adolescent; Aspartame; Brain; Child; Child, Preschool; Dopamine; Double-Blind Method; Electroencepha | 1994 |
Manipulation of cerebral monoamines in the treatment of human epilepsy: a pilot study.
Topics: Adult; Biogenic Amines; Brain Chemistry; Carbamazepine; Drug Evaluation; Epilepsy; Homovanillic Acid | 1978 |
Serotonin and myoclonus.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clinical Trials as Topic; Epilepsy; Female; Homov | 1976 |
36 other studies available for homovanillic acid and Aura
| Article | Year |
|---|---|
Secondary neurotransmitter deficiencies in epilepsy caused by voltage-gated sodium channelopathies: A potential treatment target?
Topics: Autistic Disorder; Channelopathies; Child; Drug Resistant Epilepsy; Epilepsy; Exome; Female; Homovan | 2016 |
Reversible parkinsonism following heroin pyrolysate inhalation is associated with tetrahydrobiopterin deficiency.
Topics: Adult; Biopterins; Brain; Brain Diseases, Metabolic; Electroencephalography; Epilepsy; Female; Heroi | 2004 |
Variations of dopamine, serotonin, and amino acid concentrations in Noda epileptic rat (NER) retina.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acids; Animals; Animals, Newborn; Biogenic Monoamines; | 2006 |
Secondary abnormalities of neurotransmitters in infants with neurological disorders.
Topics: 5-Hydroxytryptophan; Atrophy; Brain; Electroencephalography; Epilepsy; Female; Homovanillic Acid; Hu | 2007 |
A new fatal case of pyridox(am)ine 5'-phosphate oxidase (PNPO) deficiency.
Topics: Brain Diseases, Metabolic, Inborn; Codon, Nonsense; Epilepsy; Fatal Outcome; Genes, Recessive; Homov | 2008 |
Ontogeny of dopamine and serotonin metabolites in the cerebrospinal fluid of children with neurological disorders.
Topics: Adolescent; Child; Child, Preschool; Dopamine; Epilepsy; Female; Homovanillic Acid; Humans; Hydroxyi | 1980 |
Serotonergic and dopaminergic metabolites in cerebrospinal fluid of epileptics.
Topics: Adult; Dopamine; Epilepsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Serotonin | 1982 |
A study of urinary excretion of biogenic amine metabolites in epilepsy.
Topics: Adolescent; Adult; Biogenic Amines; Epilepsy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1983 |
Thyrotropin-releasing hormone in treatment of intractable epilepsy: neurochemical analysis of CSF monoamine metabolites.
Topics: Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Homovanillic Acid; Humans; Hydrox | 1995 |
Retinal dopamine and its metabolite contents in zitter rats and spontaneously epileptic rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Epilepsy; Homovanillic Acid; Male; Rats; Rats, In | 1993 |
[Study on dopamine metabolite in cerebrospinal fluid of schizophrenics and epilepsics].
Topics: Adult; Dopamine; Epilepsy; Female; Homovanillic Acid; Humans; Male; Middle Aged; Schizophrenia | 1998 |
Monoamine metabolites in the CSF of epileptic patients.
Topics: Adolescent; Adult; Child; Epilepsy; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic | 1979 |
Amines, anticonvulsants, and epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Chromatography, Gas; Drug Therapy, Combination; Epilepsy; | 1975 |
[Cerebrospinal fluid monoamine metabolites and cyclic nucleotides in the patients with epilepsy (author's transl)].
Topics: Adolescent; Adult; Aged; Cyclic AMP; Cyclic GMP; Epilepsy; Female; Glycols; Homovanillic Acid; Human | 1979 |
[Determination of HVA and 5-HIAA in epileptic syndromes in basal conditions and after treatment with probenecid].
Topics: Adolescent; Adult; Anticonvulsants; Brain; Dopamine; Epilepsy; Homovanillic Acid; Humans; Hydroxyind | 1979 |
Homovanillic acid in human cerebrospinal fluid.--Its concentration gradient and reduced levels in patients with epilepsy.
Topics: Adult; Child; Child, Preschool; Epilepsy; Female; Homovanillic Acid; Humans; Infant; Male; Phenylace | 1978 |
Transient hyperkinesia after a single intravenous perfusion of diphenylhydantoin. Report of a case associated with nontoxic plasma levels of diphenylhydantoin.
Topics: Adolescent; Epilepsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hyperkinesis; Infusions, | 1979 |
Effects of taurine on seizures and growth hormone release in epileptic patients.
Topics: Adolescent; Adult; Child; Epilepsy; Growth Hormone; Homovanillic Acid; Humans; Taurine | 1979 |
[Convulsions and monoamines].
Topics: Animals; Biogenic Amines; Brain Chemistry; Dopamine; Epilepsy; Homovanillic Acid; Mice; Rats; Reserp | 1978 |
[Biochemistry of epilepsy (author's transl)].
Topics: Animals; Biogenic Amines; Brain Chemistry; Catecholamines; Cats; Dopamine; Epilepsy; Guanidines; Hom | 1978 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy | 1975 |
[Homovanillic acid concentration of the cerebrospinal fluid in epilepsy].
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Ab | 1976 |
Serotonin metabolism in human epilepsy: the influence of anticonvulsant drugs.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; M | 1977 |
[Homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) levels in the lumbar cerebrospinal fluid in epileptic patients].
Topics: Adult; Epilepsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Spectrophotome | 1976 |
Folate and monoamine metabolism in epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Biogenic Amines; Epilepsy; Erythrocytes; Folic Acid; Homovanilli | 1975 |
Monoamine metabolites, iron induced seizures, and the anticonvulsant effect of tannins.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anticonvulsants; Biogenic Monoamines; Brain; Catechin; Chlo | 1992 |
Anticonvulsant activity of di-n-propylacetate and brain monoamine metabolism in the rat.
Topics: Animals; Biogenic Monoamines; Brain; Catecholamines; Epilepsy; Female; gamma-Aminobutyric Acid; Homo | 1990 |
Effects of anticonvulsant treatment and low levels of folate and thiamine on amine metabolites in cerebrospinal fluid.
Topics: Adult; Biogenic Amines; Brain; Electroencephalography; Epilepsy; Female; Folic Acid; Homovanillic Ac | 1991 |
The acute convulsant effect of MPTP is dependent on intracerebral MPP+.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemist | 1991 |
Reduction of biogenic amine levels in the Rett syndrome.
Topics: Adolescent; Ataxia; Autistic Disorder; Biogenic Amines; Child; Child, Preschool; Dementia; Electroen | 1985 |
Cerebrospinal fluid amino acid and monoamine metabolite levels of Papio papio: correlation with photosensitivity.
Topics: Amino Acids; Animals; Biogenic Amines; Epilepsy; Female; gamma-Aminobutyric Acid; Homovanillic Acid; | 1986 |
The effect of different vigabatrin treatment regimens on CSF biochemistry and seizure control in epileptic patients.
Topics: Adult; Aminocaproates; Anticonvulsants; Carnosine; Cerebrospinal Fluid Proteins; Epilepsy; Female; g | 1989 |
A study of monoamine metabolism in human epilepsy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Epilepsy; Female; Hippocampus; Homovanillic Acid; Humans; Hyd | 1989 |
Analysis of monamine metabolism in cerebrospinal fluid in childhood epilepsies.
Topics: Adolescent; Brain Damage, Chronic; Child; Child, Preschool; Epilepsies, Myoclonic; Epilepsy; Epileps | 1989 |
[Gamma-aminobutyric acid (GABA) and homovanillic acid (HVA) levels in the cerebrospinal fluid of patients with epilepsy].
Topics: Adolescent; Adult; Age Factors; Aged; Epilepsy; Female; gamma-Aminobutyric Acid; Homovanillic Acid; | 1985 |
Biogenic amines in autistic and atypical children. Cerebrospinal fluid measures of homovanillic acid and 5-hydroxyindoleacetic acid.
Topics: Autistic Disorder; Brain; Child; Child, Preschool; Diagnosis, Differential; Dopamine; Electroencepha | 1974 |