homovanillic acid has been researched along with Amyotrophic Lateral Sclerosis in 6 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In four human controls, four cases of Parkinson's disease and three cases of amyotrophic lateral sclerosis analysis of dopamine, noradrenaline, serotonin and the metabolites 3,4-dihydroxyphenylacetic acid, homovanillic acid and 5-hydroxyindoleacetic acid was performed in various segments of postmortem spinal cord." | 3.68 | Biogenic amines and metabolites in spinal cord of patients with Parkinson's disease and amyotrophic lateral sclerosis. ( Gavranovic, M; Gsell, W; Jellinger, K; Riederer, P; Schmidtke, A; Sofic, E, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takase, S | 1 |
| Yamao, S | 2 |
| Udaka, F | 1 |
| Nakamura, S | 2 |
| Andreassen, OA | 1 |
| Ferrante, RJ | 1 |
| Klivenyi, P | 1 |
| Klein, AM | 1 |
| Dedeoglu, A | 1 |
| Albers, DS | 1 |
| Kowall, NW | 1 |
| Beal, MF | 1 |
| Cook, A | 1 |
| Nidzgorski, F | 1 |
| Hurwic, M | 1 |
| Winsberg, B | 1 |
| Klutch, A | 1 |
| Sofic, E | 1 |
| Riederer, P | 1 |
| Gsell, W | 1 |
| Gavranovic, M | 1 |
| Schmidtke, A | 1 |
| Jellinger, K | 1 |
| Itoh, H | 1 |
| Akiguchi, I | 1 |
| Kameyama, M | 1 |
6 other studies available for homovanillic acid and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
[CSF findings in patients with ALS].
Topics: Adult; Aged; Albumins; Amyotrophic Lateral Sclerosis; Cerebrospinal Fluid Proteins; Complement C3; F | 1984 |
[Pathological laughing and crying in motor neuron disease].
Topics: Aged; Amyotrophic Lateral Sclerosis; Crying; Female; Homovanillic Acid; Humans; Laughter; Male; Midd | 1984 |
Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amyotrophic Lateral Sc | 2001 |
Monoamine accumulation among sclerotic patients receiving dorsal-column stimulation.
Topics: Amyotrophic Lateral Sclerosis; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Multiple Scleros | 1978 |
Biogenic amines and metabolites in spinal cord of patients with Parkinson's disease and amyotrophic lateral sclerosis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Autopsy; Bio | 1991 |
[Levodopa therapy in a patient with ALS-dementia complex].
Topics: Amyotrophic Lateral Sclerosis; Dementia; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged | 1987 |