Page last updated: 2024-10-21

homovanillic acid and Alzheimer Disease

homovanillic acid has been researched along with Alzheimer Disease in 98 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"In this study we investigated the cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in Alzheimer (AD) patients (n=75), patients with mild cognitive impairment (MCI, n=9) and patients with depression (n=7)."7.725-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment. ( Ganzer, S; Müller-Thomsen, T; Stuerenburg, HJ, 2004)
"Cerebrospinal fluid (CSF) concentration of beta-endorphin (beta-Ep), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) was measured in 15 patients with dementia of the Alzheimer type (DAT) and in 16 patients suspected of having Binswanger's disease (BD) by MRI, which sometimes resembles DAT clinically."7.68CSF beta-endorphin, HVA and 5-HIAA of dementia of the Alzheimer type and Binswanger's disease in the elderly. ( Chiba, T; Hagiwara, M; Kaieda, R; Kitahama, T; Lee, S; Nagazumi, A; Terashi, A, 1990)
"It is concluded that in severe forms of senile dementia of Alzheimer type, there is a decrease in the levels of HVA and 5-HIAA in CSF which may reflect a decreased turnover of dopamine and serotonin."5.26Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with senile dementia of Alzheimer type. ( MacDonald, E; Rekonen, M; Riekkinen, PJ; Soininen, H, 1981)
"Five patients with the early-onset form of Alzheimer disease (AD) received GM1 ganglioside by continuous injection into the frontal horns of the lateral ventricles for a period of 12 months."5.10Alzheimer disease - effect of continuous intracerebroventricular treatment with GM1 ganglioside and a systematic activation programme. ( Bråne, G; Karlsson, I; Lekman, A; Ramström, I; Svennerholm, L; Wikkelsö, C, 2002)
"In this study we investigated the cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in Alzheimer (AD) patients (n=75), patients with mild cognitive impairment (MCI, n=9) and patients with depression (n=7)."3.725-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment. ( Ganzer, S; Müller-Thomsen, T; Stuerenburg, HJ, 2004)
"Cerebrospinal fluid (CSF) concentration of beta-endorphin (beta-Ep), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) was measured in 15 patients with dementia of the Alzheimer type (DAT) and in 16 patients suspected of having Binswanger's disease (BD) by MRI, which sometimes resembles DAT clinically."3.68CSF beta-endorphin, HVA and 5-HIAA of dementia of the Alzheimer type and Binswanger's disease in the elderly. ( Chiba, T; Hagiwara, M; Kaieda, R; Kitahama, T; Lee, S; Nagazumi, A; Terashi, A, 1990)
"A distinct pattern of neuropsychological deficits was associated with low homovanillic acid (HVA) in the cerebrospinal fluid of 21 patients with: Alzheimer's disease (9), Parkinson's disease (8) and major depressive disorders (4)."3.68Neuropsychological profile linked to low dopamine: in Alzheimer's disease, major depression, and Parkinson's disease. ( Albert, ML; Almozlino, A; Durso, R; Katz, DI; Smith, MC; Volicer, L; Wolfe, N, 1990)
"Changes in the activity of neurotransmitters in dementia were studied by measuring the activities of each of choline acetyltransferase (CAT), dopamine-beta-hydroxylase (DBH) and hydroxylase cofactor (tetrahydrobiopterine; BPH4), and the concentrations of homovanillic acid (HVA) and vasopressin."3.67Neurotransmitters in dementia. ( Fujiyoshi, K; Iijima, S; Kato, T; Koshimura, K; Miyata, S; Nagata, H; Nakamura, S; Okamoto, K; Suga, H; Yamao, S, 1984)
" Lumbar cerebrospinal fluid (CSF) neurotransmitter metabolite levels for homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), and 3-methoxy-4-hydroxyphenyl glycol (MHPG) were determined in patients with schizophrenia and Alzheimer's disease."3.67Seasonal variations of human lumbar CSF neurotransmitter metabolite concentrations. ( Davis, KL; Losonczy, MF; Mohs, RC, 1984)
" We tested patients with PD, patients with Alzheimer's type of senile dementia, and a control group neuropsychologically, and we determined their CSF levels of homovanillic acid, 3,4-dihydroxyphenylacetic acid, 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindolacetic acid, serotonin, and acetylcholinesterase."3.67Parkinson's disease. The possible relationship of laterality to dementia and neurochemical findings. ( Albert, ML; Direnfeld, LK; Kaplan, E; Langlais, PJ; Marquis, J; Volicer, L, 1984)
"Patients with Alzheimer disease (AD, onset less than 65 years of age, n = 13) and senile dementia of the Alzheimer type (SDAT, onset greater than or equal to 65 years of age, n = 28) were investigated for cerebrospinal fluid (CSF) content of homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxy-phenylglycol (MHPG) and compared with a group of controls (n = 26)."3.67Monoamine metabolites in cerebrospinal fluid and behavioral ratings in patients with early and late onset of Alzheimer dementia. ( Blennow, K; Bråne, G; Gottfries, CG; Karlsson, I; Lekman, A; Parnetti, L; Svennerholm, L; Wallin, A, 1989)
"Mean levels of the two hydrolases angiotensin-converting enzyme (ACE) and acetylcholinesterase (AChE), the dopamine metabolites dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), and total protein concentration were examined in cerebrospinal fluid (CSF) samples from a group of patients with dementia of the Alzheimer's type, a group of comparably demented patients with Parkinson's disease, and a neurologically healthy elderly control group."3.67Cerebrospinal fluid levels of angiotensin-converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson's disease: a correlative study. ( Direnfeld, LK; Langlais, PJ; Marquis, JK; Nixon, RA; Volicer, L; Zubenko, GS, 1986)
"Noradrenaline, dopamine, homovanillic acid (HVA), choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) levels were measured in post-mortem brains from 8 cases of pre-senile Alzheimer-type dementia (ATD), 5 cases of senile ATD, 4 cases of Down's syndrome aged 53-57 years, one 27-year-old case of Down's syndrome and 13 controls."3.66Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome. ( Allison, Y; Gordon, A; Maloney, AF; Ritchie, IM; Simpson, J; Urquhart, A; Yates, CM, 1983)
" Pharmacokinetic investigations showed that the oral bioavailability of tacrine was low and greatly varying between subjects."2.67Clinical experiences and biochemical findings with tacrine (THA). ( Ahlin, A; Hassan, M; Junthé, T; Nybäck, H, 1993)
"Abnormalities found in senile or presenile dementia were not always parallel to the age-related changes."2.38Senile dementia and presenile dementia. ( Nakamura, S, 1990)
"Patients with Alzheimer's disease (AD) have been reported to have a rate of nonsuppression on the dexamethasone suppression test (DST) comparable to that of patients with major depression."2.38The dexamethasone suppression test in Alzheimer's disease and major depression: relationship to dementia severity, depression, and CSF monoamines. ( Hill, JL; Lawlor, BA; Martinez, R; Mellow, AM; Molchan, SE; Sunderland, T, 1990)
"Dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are the two most common causes of dementia."1.46Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer's disease: An autopsy-confirmed study. ( Hatsuta, H; Kanemaru, K; Komiya, T; Morimoto, S; Murayama, S; Nakano, Y; Nishina, Y; Saito, Y; Sengoku, R; Sumikura, H; Takao, M; Uchino, A, 2017)
"Neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) are present during the disease course of nearly all AD patients and consist of psychosis, agitation/aggression, and depression, among others."1.40Brain region-specific monoaminergic correlates of neuropsychiatric symptoms in Alzheimer's disease. ( Aerts, T; De Deyn, PP; Engelborghs, S; Van Dam, D; Vermeiren, Y, 2014)
"Depression and aggression in Alzheimer's disease (AD) are 2 of the most severe and prominent neuropsychiatric symptoms (NPS)."1.40Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease. ( Aerts, T; De Deyn, PP; Engelborghs, S; Van Dam, D; Vermeiren, Y, 2014)
"Delirium is a complex neuropsychiatric syndrome with an acute onset and fluctuating course."1.33Abnormal neurotransmitter metabolite levels in Alzheimer patients with a delirium. ( Engelhart, MJ; Fekkes, D; Tiemeier, H; van der Cammen, TJ, 2006)
"Subjects with Alzheimer type dementia (AD), vascular dementia (VD), and controls without dementia (C) were investigated."1.30Blood-brain barrier permeability of the demented elderly as studied by cerebrospinal fluid-serum albumin ratio. ( Wada, H, 1998)
"Distinguishing Alzheimer's disease from DLB is clinically relevant in terms of prognosis and appropriate treatment."1.30Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution. ( Ballard, C; Burn, D; Court, JA; Jaros, E; Johnson, M; Lloyd, S; Marshall, EF; McKeith, IG; Perry, EK; Perry, RH; Piggott, MA; Thomas, N, 1999)
" In the second phase of this study the same 12 PDD patients were treated with GAP at a daily dosage of 250 lipasemic-releasing units for a period of 1 month and it was found that all four biochemical parameters shifted towards normal values during therapy with the changes in CSF 5-hydroxy-indole acetic acid levels attaining statistical significance."1.29Glycosaminoglycan polysulfate in primary degenerative dementia. Pilot study of biologic and clinical effects. ( Ban, TA; Parnetti, L; Senin, U, 1995)
"Patients with the Lewy body variant of Alzheimer's disease tended to experience more frequent extrapyramidal side effects of neuroleptics than did the patients with Alzheimer's disease, but for patients in the two groups who were not exposed to neuroleptics, there was little difference in frequency of extrapyramidal side effects."1.29Alzheimer's disease and its Lewy body variant: a clinical analysis of postmortem verified cases. ( Cullum, CM; Honig, L; Risser, RC; Rosenberg, RN; Speciale, S; Weiner, MF; White, C, 1996)
"In contrast to senile dementia of Alzheimer's type SLI was not correlated with dementia scores but with motor disease progression."1.28Parkinson's disease and dementia: clinical and neurochemical correlations. ( Cramer, H; Strittmatter, MM, 1992)
"Patients who had Alzheimer's disease-senile dementia of the Alzheimer type (AD/SDAT) or multi-infarct dementia (MID) were compared with a group of controls."1.27Dementia of the Alzheimer type and multi-infarct dementia: a clinical description and diagnostic problems. ( Adolfsson, R; Bucht, G; Winblad, B, 1984)
"Patients with Parkinson's disease have a decrement in homovanillic acid that is reversed by treatment with L-3,4-dihydroxyphenylalanine."1.27Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method. ( Aguado, EG; de Yebenes, JG; Mena, MA, 1984)
"The nbM from patients with Alzheimer's disease showed significant decreases in both spiperone binding and in the levels of dopamine and serotonin but no decrease in either tyrosine or tryptophan levels."1.27Alzheimer's disease: monoamines and spiperone binding reduced in nucleus basalis. ( Markesbery, WR; Slevin, JT; Sparks, DL, 1986)
"5-Hydroxyindoleacetic acid was significantly lower in patients with myoclonic DAT as compared to patients with nonmyoclonic DAT, but not significantly lower than in control subjects."1.27Cerebrospinal fluid neurochemistry in the myoclonic subtype of Alzheimer's disease. ( Atack, JR; Beal, MF; Daly, E; Friedland, RP; Kaufman, S; Kaye, JA; May, C; Milstien, S; Rapoport, SI; Sweeney, DL, 1988)
"It is concluded that in severe forms of senile dementia of Alzheimer type, there is a decrease in the levels of HVA and 5-HIAA in CSF which may reflect a decreased turnover of dopamine and serotonin."1.26Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with senile dementia of Alzheimer type. ( MacDonald, E; Rekonen, M; Riekkinen, PJ; Soininen, H, 1981)
"The diagnosis of Alzheimer's disease (13 patients) and Pick's disease (4 patients) has been made on clinical and radiological grounds."1.26[Cerebral metabolism of dopamine and of serotonin during Alzheimer and Pick's diseases. Dynamic study by the test using probenecid]. ( Chazot, G; Guard, O; Renaud, B, 1976)

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199053 (54.08)18.7374
1990's34 (34.69)18.2507
2000's7 (7.14)29.6817
2010's4 (4.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vermeiren, Y2
Van Dam, D2
Aerts, T2
Engelborghs, S3
De Deyn, PP3
Esteban, G1
Van Schoors, J1
Sun, P1
Van Eeckhaut, A1
Marco-Contelles, J1
Smolders, I1
Unzeta, M1
Morimoto, S1
Takao, M1
Hatsuta, H1
Nishina, Y1
Komiya, T1
Sengoku, R1
Nakano, Y1
Uchino, A1
Sumikura, H1
Saito, Y1
Kanemaru, K2
Murayama, S1
Svennerholm, L4
Bråne, G2
Karlsson, I3
Lekman, A2
Ramström, I1
Wikkelsö, C2
Sjögren, M1
Ostling, S1
Wallin, A2
Blennow, K2
Yamanouchi, H1
Vloeberghs, E1
Maertens, K1
Marescau, B1
Stuerenburg, HJ1
Ganzer, S1
Müller-Thomsen, T1
van der Cammen, TJ1
Tiemeier, H1
Engelhart, MJ1
Fekkes, D1
Muramoto, O1
Ando, K1
Nakamura, S3
Koshimura, K1
Kato, T1
Yamao, S1
Iijima, S1
Nagata, H1
Miyata, S2
Fujiyoshi, K1
Okamoto, K1
Suga, H1
Argentiero, V1
Tavolato, B1
Soininen, H2
MacDonald, E1
Rekonen, M1
Riekkinen, PJ4
Bareggi, SR1
Franceschi, M1
Bonini, L1
Zecca, L1
Smirne, S1
Wood, PL1
Etienne, P1
Lal, S1
Gauthier, S1
Cajal, S1
Nair, NP1
Gottfries, CG8
Adolfsson, R5
Aquilonius, SM1
Carlsson, A2
Eckernäs, SA1
Nordberg, A1
Oreland, L1
Wiberg, A1
Winblad, B4
Bucht, G1
Palmer, AM4
Sims, NR2
Bowen, DM6
Neary, D4
Palo, J1
Wikstrom, J1
Davison, AN2
Mena, MA1
Aguado, EG1
de Yebenes, JG1
Losonczy, MF1
Mohs, RC3
Davis, KL3
Yates, CM2
Simpson, J2
Gordon, A2
Maloney, AF1
Allison, Y1
Ritchie, IM1
Urquhart, A1
Cross, AJ1
Crow, TJ1
Ferrier, IN1
Johnson, JA1
Markakis, D1
Direnfeld, LK3
Albert, ML3
Volicer, L4
Langlais, PJ4
Marquis, J1
Kaplan, E1
Zimmer, R1
Teelken, AW1
Trieling, WB1
Weber, W1
Weihmayr, T1
Lauter, H1
Mann, JJ1
Stanley, M3
Neophytides, A1
de Leon, MJ1
Ferris, SH1
Gershon, S1
Benton, JS2
Curzon, G1
Thomas, DJ2
Nybäck, H3
Hassan, M1
Junthé, T1
Ahlin, A1
Parnetti, L3
Ban, TA1
Senin, U1
Francis, PT3
Pangalos, MN1
Stephens, PH1
Bartlett, JR1
Bridges, PK1
Malizia, AL1
Procter, AW2
Alhainen, K1
Helkala, EL3
Reinikainen, K1
Riekkinen, P1
Thal, L1
Hansen, L1
Galasko, D1
Alford, M1
Masliah, E1
Bierer, LM1
Knott, PJ1
Schmeidler, JM1
Marin, DB1
Ryan, TM1
Haroutunian, V1
Purohit, DP1
Perl, DP1
Weiner, MF1
Risser, RC1
Cullum, CM1
Honig, L1
White, C1
Speciale, S1
Rosenberg, RN1
Strittmatter, M1
Hamann, G1
Cramer, H2
Reuner, C1
Kuntzmann, F1
Strubel, D1
Sweet, RA1
Pollock, BG1
Mulsant, BH1
Rosen, J1
Lo, KH1
Yao, JK1
Henteleff, RA1
Mazumdar, S1
Sheline, YI1
Miller, K1
Bardgett, ME1
Csernansky, JG1
Wada, H1
Hoogendijk, WJ1
Feenstra, MG1
Botterblom, MH1
Gilhuis, J1
Sommer, IE1
Kamphorst, W1
Eikelenboom, P1
Swaab, DF1
Piggott, MA1
Marshall, EF1
Thomas, N1
Lloyd, S1
Court, JA1
Jaros, E1
Burn, D1
Johnson, M1
Perry, RH1
McKeith, IG1
Ballard, C1
Perry, EK2
del Ser, T1
Davies, P1
Roos, BE2
Meyer, JS1
Welch, KM1
Deshmukh, VD1
Perez, FI1
Jacob, RH1
Haufrect, DB1
Mathew, NT1
Morrell, RM1
Guard, O1
Renaud, B1
Chazot, G1
Siever, L1
Kraemer, H1
Sack, R1
Angwin, P1
Berger, P1
Zarcone, V1
Barchas, J1
Brodie, HK1
Pomara, N2
LeWitt, PA2
Galloway, M1
Singh, R1
Deptula, D2
Nazarali, AJ1
Reynolds, GP2
Laulumaa, V1
Hartikainen, P1
Strittmatter, MM1
Arai, H1
Ichimiya, Y1
Kosaka, K1
Moroji, T1
Iizuka, R1
Lee, S1
Chiba, T1
Kitahama, T1
Kaieda, R1
Hagiwara, M1
Nagazumi, A1
Terashi, A1
Kawakatsu, S1
Morinobu, S1
Shinohara, M1
Totsuka, S1
Kobashi, K1
Nyth, AL1
Malm, J1
Kristensen, B1
Ekstedt, J1
Wester, P1
Martignoni, E1
Bono, G1
Blandini, F1
Sinforiani, E1
Merlo, P1
Nappi, G1
Molchan, SE3
Hill, JL2
Mellow, AM3
Lawlor, BA3
Martinez, R1
Sunderland, T5
Martinez, RA2
Davis, CL1
Rubinow, DR1
Berrettini, WH1
Vitiello, B1
Tariot, PN2
Cohen, RM2
Nyman, H2
Blomqvist, G1
Sjögren, I1
Stone-Elander, S1
McKeith, I1
Thompson, P1
Marshall, E1
Kerwin, J1
Jabeen, S1
Edwardson, JA1
Ince, P1
Blessed, G1
Irving, D1
Liu, HC1
Yang, JC1
Chang, YF1
Liu, TY1
Chi, CW1
Allard, P1
Alafuzoff, I1
Eriksson, K1
Ericson, E1
Marcusson, JO1
Tyrrell, PJ1
Sawle, GV1
Ibanez, V1
Bloomfield, PM1
Leenders, KL1
Frackowiak, RS1
Rossor, MN1
Wolfe, N1
Katz, DI1
Almozlino, A1
Durso, R1
Smith, MC1
Seeldrayers, P1
Messina, D1
Desmedt, D1
Dalesio, O1
Hildebrand, J1
Cutler, NR2
Haxby, J1
Kay, AD3
Narang, PK1
Lesko, LJ1
Costa, JL1
Ninos, M1
Linnoila, M1
Potter, WZ2
Renfrew, JW1
Davis, BM1
Greenwald, BS1
Mathé, AA1
Johns, CA1
Horvath, TB1
Degrell, I1
Pék, G1
Nagy, D1
Nagy, E1
Hoyer, S1
Sparks, DL1
Markesbery, WR1
Slevin, JT1
Milstien, S3
Kaufman, S3
Creasey, H1
Haxby, JV1
Rapoport, SI2
Wilcock, GK1
Esiri, MM1
Newhouse, PA1
Mueller, EA1
Murphy, DL1
Mayeux, R1
Stern, Y1
Sano, M1
Cote, L1
Williams, JB1
Gottfries, J1
Långström, G1
Godridge, H1
Czudek, C1
Calcutt, NA1
Benton, M1
Risby, ED1
Hsiao, JK1
Agren, H1
Rudorfer, MV1
Schalling, D1
Kaye, JA2
May, C2
Daly, E2
Atack, JR2
Sweeney, DJ1
Luxenberg, JS1
Friedland, RP2
Koyama, E1
Minegishi, A1
Ishizaki, T1
Stratmann, GC1
Freed, DM1
Corkin, S1
Growdon, JH2
Nissen, MJ1
Sweeney, DL1
Beal, MF1
Jolkkonen, J1
Kutvonen, R1
Lehtinen, M1
Singh, RR1
Bissette, G1
Nemeroff, CB1
Corona, GL1
Cucchi, ML1
Frattini, P1
Santagostino, G1
Schinelli, S1
Romani, A1
Pola, A1
Zerbi, F1
Savoldi, F1
Gibson, CJ1
Logue, M1
Shigetomi, S1
Jolkkonen, JT1
Soininen, HS1
Freedman, M1
Bird, ED1
Zubenko, GS1
Marquis, JK1
Nixon, RA1
Mann, DM1
Snowden, JS1

Reviews

4 reviews available for homovanillic acid and Alzheimer Disease

ArticleYear
[Biogenic amines and aging (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1981, Volume: 26, Issue:11

    Topics: Adult; Aged; Aging; Alzheimer Disease; Biogenic Amines; Brain; Catecholamines; Homovanillic Acid; Hu

1981
[Clinical manifestation of frontotemporal dementia].
    Neurologia (Barcelona, Spain), 2000, Volume: 15 Suppl 1

    Topics: Alzheimer Disease; Atrophy; Cognition Disorders; Diagnosis, Differential; Frontal Lobe; Homovanillic

2000
Senile dementia and presenile dementia.
    The Tohoku journal of experimental medicine, 1990, Volume: 161 Suppl

    Topics: Acetylcholinesterase; Alzheimer Disease; Arginine Vasopressin; Biopterins; Brain Chemistry; Cerebral

1990
The dexamethasone suppression test in Alzheimer's disease and major depression: relationship to dementia severity, depression, and CSF monoamines.
    International psychogeriatrics, 1990,Fall, Volume: 2, Issue:2

    Topics: Aged; Alzheimer Disease; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; Hydr

1990

Trials

9 trials available for homovanillic acid and Alzheimer Disease

ArticleYear
Alzheimer disease - effect of continuous intracerebroventricular treatment with GM1 ganglioside and a systematic activation programme.
    Dementia and geriatric cognitive disorders, 2002, Volume: 14, Issue:3

    Topics: Aged; Alzheimer Disease; Cerebrovascular Circulation; Female; G(M1) Ganglioside; Homovanillic Acid;

2002
Clinical experiences and biochemical findings with tacrine (THA).
    Acta neurologica Scandinavica. Supplementum, 1993, Volume: 149

    Topics: Administration, Rectal; Alzheimer Disease; Biogenic Monoamines; Cross-Sectional Studies; Double-Blin

1993
Neurochemical parameters in senile dementia of the Alzheimer type. A longitudinal study in four cases.
    European archives of psychiatry and clinical neuroscience, 1996, Volume: 246, Issue:2

    Topics: Alzheimer Disease; Antidepressive Agents; Antipsychotic Agents; Brain Chemistry; Homovanillic Acid;

1996
Association of plasma homovanillic acid with behavioral symptoms in patients diagnosed with dementia: a preliminary report.
    Biological psychiatry, 1997, Dec-01, Volume: 42, Issue:11

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Behavior; Dyskinesia, Drug-Induced

1997
The clinical efficacy of citalopram in treatment of emotional disturbances in dementia disorders. A Nordic multicentre study.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 157

    Topics: Affective Symptoms; Aged; Alzheimer Disease; Citalopram; Dementia, Multi-Infarct; Double-Blind Metho

1990
Monoamines and related metabolite levels in the cerebrospinal fluid of patients with dementia of Alzheimer type. Influence of treatment with L-deprenyl.
    Journal of neural transmission. Parkinson's disease and dementia section, 1991, Volume: 3, Issue:1

    Topics: Aged; Alzheimer Disease; Biogenic Monoamines; Cognition; Dopamine; Double-Blind Method; Epinephrine;

1991
Evaluation of zimeldine in Alzheimer's disease. Cognitive and biochemical measures.
    Archives of neurology, 1985, Volume: 42, Issue:8

    Topics: Aged; Alzheimer Disease; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; Homovanilli

1985
Clinical and biochemical responses to therapy in Alzheimer's disease and multi-infarct dementia.
    European archives of psychiatry and neurological sciences, 1989, Volume: 239, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arousal; Blood Pressure; Choline; Clinical Trials as Top

1989
The effect of ACTH4-9 analog (Org2766) on some cerebrospinal fluid parameters in patients with Alzheimer's disease.
    Life sciences, 1985, Aug-19, Volume: 37, Issue:7

    Topics: Adrenocorticotropic Hormone; Aged; Alzheimer Disease; Cholinesterases; Cyclic AMP; Dopamine beta-Hyd

1985

Other Studies

85 other studies available for homovanillic acid and Alzheimer Disease

ArticleYear
Brain region-specific monoaminergic correlates of neuropsychiatric symptoms in Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 41, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Alzheimer Disease; Autopsy; Biogenic Monoam

2014
Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease.
    Neurobiology of aging, 2014, Volume: 35, Issue:12

    Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Brain; Chromatography, High Pressure Liquid;

2014
In-vitro and in-vivo evaluation of the modulatory effects of the multitarget compound ASS234 on the monoaminergic system.
    The Journal of pharmacy and pharmacology, 2017, Volume: 69, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Animals; Biogenic Monoamines; Cell Line, Tumor; D

2017
Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer's disease: An autopsy-confirmed study.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Autopsy; Biomarkers; Diagn

2017
Biological correlates of clinical subgroups of Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2002, Volume: 14, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Biomarkers; Brain;

2002
Assessment of CSF homovanillic acid levels distinguishes dementia with Lewy bodies from Alzheimer's disease.
    Journal of neurology, 2002, Volume: 249, Issue:8

    Topics: Aged; Alzheimer Disease; Diagnosis, Differential; Female; Homovanillic Acid; Humans; Lewy Body Disea

2002
Evidence for an association between the CSF HVA:5-HIAA ratio and aggressiveness in frontotemporal dementia but not in Alzheimer's disease.
    Journal of neurology, neurosurgery, and psychiatry, 2004, Volume: 75, Issue:7

    Topics: Aged; Aggression; Alzheimer Disease; Dementia; Diagnosis, Differential; Follow-Up Studies; Frontal L

2004
5-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment.
    Neuro endocrinology letters, 2004, Volume: 25, Issue:6

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Depression; Dopamine; Female; Homovanillic Acid; Human

2004
Abnormal neurotransmitter metabolite levels in Alzheimer patients with a delirium.
    International journal of geriatric psychiatry, 2006, Volume: 21, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Case-Control Studies; Delirium; Female; Hom

2006
Neurotransmitters in dementia.
    Clinical therapeutics, 1984, Volume: 7 Spec No

    Topics: Adult; Aged; Alzheimer Disease; Arginine Vasopressin; Biopterins; Central Nervous System; Cerebral C

1984
Dopamine (DA) and serotonin metabolic levels in the cerebrospinal fluid (CSF) in Alzheimer's presenile dementia under basic conditions and after stimulation with cerebral cortex phospholipids (BC-PL).
    Journal of neurology, 1980, Volume: 224, Issue:1

    Topics: Alzheimer Disease; Cerebral Cortex; Dementia; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacet

1980
Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with senile dementia of Alzheimer type.
    Acta neurologica Scandinavica, 1981, Volume: 64, Issue:2

    Topics: Aged; Alzheimer Disease; Butyrophenones; Dementia; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac

1981
Decreased CSF concentrations of homovanillic acid and gamma-aminobutyric acid in Alzheimer's disease. Age- or disease-related modifications?
    Archives of neurology, 1982, Volume: 39, Issue:11

    Topics: Age Factors; Aged; Aging; Alzheimer Disease; Brain Chemistry; Dementia; Female; gamma-Aminobutyric A

1982
Reduced lumbar CSF somatostatin levels in Alzheimer's disease.
    Life sciences, 1982, Nov-08, Volume: 31, Issue:19

    Topics: Aged; Alcohol Amnestic Disorder; Alzheimer Disease; Dementia; Female; Homovanillic Acid; Humans; Hyd

1982
Biochemical changes in dementia disorders of Alzheimer type (AD/SDAT).
    Neurobiology of aging, 1983,Winter, Volume: 4, Issue:4

    Topics: Aged; Alzheimer Disease; Brain; Choline O-Acetyltransferase; Female; Gangliosides; Homovanillic Acid

1983
Dementia of the Alzheimer type and multi-infarct dementia: a clinical description and diagnostic problems.
    Journal of the American Geriatrics Society, 1984, Volume: 32, Issue:7

    Topics: Aged; Alzheimer Disease; Blood Chemical Analysis; Cardiovascular Diseases; Dementia; Diagnosis, Diff

1984
Monoamine metabolite concentrations in lumbar cerebrospinal fluid of patients with histologically verified Alzheimer's dementia.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:5

    Topics: Aged; Alzheimer Disease; Brain; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid

1984
Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method.
    Acta neurologica Scandinavica, 1984, Volume: 69, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Depression;

1984
Seasonal variations of human lumbar CSF neurotransmitter metabolite concentrations.
    Psychiatry research, 1984, Volume: 12, Issue:1

    Topics: Adult; Alzheimer Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxy

1984
Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome.
    Brain research, 1983, Nov-28, Volume: 280, Issue:1

    Topics: Acetylcholinesterase; Adult; Aged; Aging; Alzheimer Disease; Brain; Choline O-Acetyltransferase; Dem

1983
Striatal dopamine receptors in Alzheimer-type dementia.
    Neuroscience letters, 1984, Nov-23, Volume: 52, Issue:1-2

    Topics: Aged; Alzheimer Disease; Choline O-Acetyltransferase; Dementia; Female; gamma-Aminobutyric Acid; Hom

1984
Parkinson's disease. The possible relationship of laterality to dementia and neurochemical findings.
    Archives of neurology, 1984, Volume: 41, Issue:9

    Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Cognition; Dementia; Functional Laterality; Homovanil

1984
Gamma-aminobutyric acid and homovanillic acid concentration in the CSF of patients with senile dementia of Alzheimer's type.
    Archives of neurology, 1984, Volume: 41, Issue:6

    Topics: Aged; Alzheimer Disease; Dementia; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Middl

1984
Central amine metabolism in Alzheimer's disease: in vivo relationship to cognitive deficit.
    Neurobiology of aging, 1981,Spring, Volume: 2, Issue:1

    Topics: Aged; Alzheimer Disease; Blood Platelets; Cognition Disorders; Dementia; Glycols; Homovanillic Acid;

1981
Treatment of Alzheimer's disease: a cautionary note.
    The New England journal of medicine, 1981, Oct-22, Volume: 305, Issue:17

    Topics: Adult; Aged; Alzheimer Disease; Dementia; Homovanillic Acid; Humans; Male; Middle Aged

1981
Glycosaminoglycan polysulfate in primary degenerative dementia. Pilot study of biologic and clinical effects.
    Neuropsychobiology, 1995, Volume: 31, Issue:2

    Topics: Aged; Alzheimer Disease; Blood Platelets; Female; Glycosaminoglycans; Homovanillic Acid; Humans; Hyd

1995
Antemortem measurements of neurotransmission: possible implications for pharmacotherapy of Alzheimer's disease and depression.
    Journal of neurology, neurosurgery, and psychiatry, 1993, Volume: 56, Issue:1

    Topics: Adult; Alzheimer Disease; Antidepressive Agents; Antipsychotic Agents; Cerebral Ventricles; Female;

1993
The relationship of cerebrospinal fluid monoamine metabolites with clinical response to tetrahydroaminoacridine in patients with Alzheimer's disease.
    Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 5, Issue:3

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Biogenic Monoamines; Female;

1993
Neurotransmitters in basal ganglia and cortex of Alzheimer's disease with and without Lewy bodies.
    Neurology, 1993, Volume: 43, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Basal Ganglia; Brain; Brain Chemistry; Caudate Nu

1993
Post-mortem examination of dopaminergic parameters in Alzheimer's disease: relationship to noncognitive symptoms.
    Psychiatry research, 1993, Volume: 49, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Alzheimer Disease; Dopamine; Female; Homova

1993
Alzheimer's disease and its Lewy body variant: a clinical analysis of postmortem verified cases.
    The American journal of psychiatry, 1996, Volume: 153, Issue:10

    Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Basal Ganglia Diseases; Body Height; Delusions; Diagn

1996
Higher cerebrospinal fluid MHPG in subjects with dementia of the Alzheimer type. Relationship with cognitive dysfunction.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1998,Spring, Volume: 6, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Female; Homovanillic Acid; Humans;

1998
Blood-brain barrier permeability of the demented elderly as studied by cerebrospinal fluid-serum albumin ratio.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:6

    Topics: Aged; Aged, 80 and over; Albumins; alpha 1-Antichymotrypsin; Alzheimer Disease; Blood-Brain Barrier;

1998
Increased activity of surviving locus ceruleus neurons in Alzheimer's disease.
    Annals of neurology, 1999, Volume: 45, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Amygdala; Cell Count; Cell Survival; Dopamine; Fe

1999
Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution.
    Brain : a journal of neurology, 1999, Volume: 122 ( Pt 8)

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autoradiography; Corpus Striatum; Dementia; Dopamine; Fe

1999
Biochemical changes in Alzheimer's disease-senile dementia: neurotransmitters in senile dementia of the Alzheimer's type.
    Research publications - Association for Research in Nervous and Mental Disease, 1979, Volume: 57

    Topics: Acetylcholine; Acetylcholinesterase; Aged; Alzheimer Disease; Brain; Choline O-Acetyltransferase; De

1979
Cathecholamines in the human brain and ageing.
    Scandinavian journal of social medicine. Supplementum, 1977, Volume: 14

    Topics: Aged; Aging; Alzheimer Disease; Autopsy; Brain; Dementia; Dopamine; Homovanillic Acid; Humans; Norep

1977
Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease.
    Journal of the American Geriatrics Society, 1977, Volume: 25, Issue:7

    Topics: 5-Hydroxytryptophan; Aged; Alzheimer Disease; Carbidopa; Dementia; Dopamine; Drug Combinations; Fema

1977
Changes in the brain catecholamines in patients with dementia of Alzheimer type.
    The British journal of psychiatry : the journal of mental science, 1979, Volume: 135

    Topics: Aged; Alzheimer Disease; Brain; Catecholamines; Dementia; Dopamine; Female; Homovanillic Acid; Human

1979
[Cerebral metabolism of dopamine and of serotonin during Alzheimer and Pick's diseases. Dynamic study by the test using probenecid].
    L'Encephale, 1976, Volume: 2, Issue:4

    Topics: Aged; Alzheimer Disease; Brain Chemistry; Dementia; Dopamine; Female; Homovanillic Acid; Humans; Hyd

1976
Gradients of biogenic amine metabolites in cerebrospinal fluid.
    Diseases of the nervous system, 1975, Volume: 36, Issue:1

    Topics: Alzheimer Disease; Amphetamine; Brain Diseases; Brain Neoplasms; Depression; Homovanillic Acid; Huma

1975
Increased CSF HVA response to arecoline challenge in Alzheimer's disease.
    Journal of neural transmission. General section, 1992, Volume: 90, Issue:1

    Topics: Aged; Alzheimer Disease; Arecoline; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mal

1992
Monoamine neurotransmitters and their metabolites in brain regions in Alzheimer's disease: a postmortem study.
    Cellular and molecular neurobiology, 1992, Volume: 12, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amygdala; Brain Chemistry; Caudate Nucleus; Dementia; Do

1992
Extrapyramidal signs in Alzheimer's disease: a 3-year follow-up study.
    Journal of neural transmission. Parkinson's disease and dementia section, 1992, Volume: 4, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Basal Ganglia Diseases; Dopamine;

1992
Parkinson's disease and dementia: clinical and neurochemical correlations.
    Neuroreport, 1992, Volume: 3, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic A

1992
Neurotransmitter changes in early- and late-onset Alzheimer-type dementia.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain Chemistry; Choline O-Acetyltransferase; Hom

1992
5-Hydroxytryptamine and dopamine in pre-senile and senile Alzheimer-type dementia.
    Biochemical Society transactions, 1990, Volume: 18, Issue:3

    Topics: Age Factors; Aged; Alzheimer Disease; Amygdala; Brain; Caudate Nucleus; Dopamine; Homovanillic Acid;

1990
CSF beta-endorphin, HVA and 5-HIAA of dementia of the Alzheimer type and Binswanger's disease in the elderly.
    Journal of neural transmission. Supplementum, 1990, Volume: 30

    Topics: Alzheimer Disease; beta-Endorphin; Dementia; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic

1990
Acetylcholinesterase activities and monoamine metabolite levels in the cerebrospinal fluid of patients with Alzheimer's disease.
    Biological psychiatry, 1990, Sep-01, Volume: 28, Issue:5

    Topics: Acetylcholinesterase; Adult; Aged; Alzheimer Disease; Brain; Butyrylcholinesterase; Cerebral Ventric

1990
CSF monoamine metabolites, cholinesterases and lactate in the adult hydrocephalus syndrome (normal pressure hydrocephalus) related to CSF hydrodynamic parameters.
    Journal of neurology, neurosurgery, and psychiatry, 1991, Volume: 54, Issue:3

    Topics: Aged; Alzheimer Disease; Cerebrospinal Fluid Pressure; Cholinesterases; Dementia, Multi-Infarct; Fem

1991
CSF monoamine metabolites and somatostatin in Alzheimer's disease and major depression.
    Biological psychiatry, 1991, Jun-01, Volume: 29, Issue:11

    Topics: Aged; Alzheimer Disease; Depressive Disorder; Diagnosis, Differential; Female; Homovanillic Acid; Hu

1991
Reduced cerebrospinal fluid dynorphin A1-8 in Alzheimer's disease.
    Biological psychiatry, 1991, Jul-01, Volume: 30, Issue:1

    Topics: Aged; Alzheimer Disease; Brain; Depressive Disorder; Dynorphins; Female; Galanin; Homovanillic Acid;

1991
Brain metabolism in Alzheimer's dementia: studies of 11C-deoxyglucose accumulation, CSF monoamine metabolites and neuropsychological test performance in patients and healthy subjects.
    Journal of neurology, neurosurgery, and psychiatry, 1991, Volume: 54, Issue:8

    Topics: Aged; Alzheimer Disease; Blood Glucose; Brain; Brain Mapping; Cerebral Cortex; Deoxyglucose; Dominan

1991
Topography, extent, and clinical relevance of neurochemical deficits in dementia of Lewy body type, Parkinson's disease, and Alzheimer's disease.
    Annals of the New York Academy of Sciences, 1991, Volume: 640

    Topics: Adult; Aged; Alzheimer Disease; Cerebral Cortex; Choline O-Acetyltransferase; Dementia; Hallucinatio

1991
Analysis of monoamines in the cerebrospinal fluid of Chinese patients with Alzheimer's disease.
    Annals of the New York Academy of Sciences, 1991, Volume: 640

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; China; Chromatography, High Pressure Liquid; Dihy

1991
Loss of dopamine uptake sites labeled with [3H]GBR-12935 in Alzheimer's disease.
    European neurology, 1990, Volume: 30, Issue:4

    Topics: Aged; alpha-Methyltyrosine; Alzheimer Disease; Dopamine; Female; Homovanillic Acid; Humans; In Vitro

1990
Clinical and positron emission tomographic studies in the 'extrapyramidal syndrome' of dementia of the Alzheimer type.
    Archives of neurology, 1990, Volume: 47, Issue:12

    Topics: Adult; Aged; Alzheimer Disease; Caudate Nucleus; Dementia; Dopamine; Homovanillic Acid; Humans; Midd

1990
Neuropsychological profile linked to low dopamine: in Alzheimer's disease, major depression, and Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:10

    Topics: Aged; Alzheimer Disease; Attention; Depressive Disorder; Dopamine; Homovanillic Acid; Humans; Male;

1990
CSF levels of neurotransmitters in Alzheimer-type dementia. Effects of ergoloid mesylate.
    Acta neurologica Scandinavica, 1985, Volume: 71, Issue:5

    Topics: Aged; Alzheimer Disease; Dihydroergotoxine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic A

1985
Clinical studies of the cholinergic deficit in Alzheimer's disease. I. Neurochemical and neuroendocrine studies.
    Journal of the American Geriatrics Society, 1985, Volume: 33, Issue:11

    Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Choline; Choline Deficiency; Cognition; Female; Gas C

1985
Dementias, psychological tests, and neurotransmitters.
    Archives of gerontology and geriatrics, 1985, Volume: 4, Issue:4

    Topics: Aged; Alcoholism; Alzheimer Disease; Dementia; Diagnosis, Differential; Female; Homovanillic Acid; H

1985
Alzheimer's disease: monoamines and spiperone binding reduced in nucleus basalis.
    Annals of neurology, 1986, Volume: 19, Issue:6

    Topics: Aged; Alzheimer Disease; Basal Ganglia; Biogenic Amines; Dopamine; Homovanillic Acid; Humans; Hydrox

1986
Cerebrospinal fluid biopterin is decreased in Alzheimer's disease.
    Archives of neurology, 1986, Volume: 43, Issue:10

    Topics: Adult; Aged; Alzheimer Disease; Biopterins; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindo

1986
Monoaminergic innervation of the frontal and temporal lobes in Alzheimer's disease.
    Brain research, 1987, Jan-20, Volume: 401, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Biogenic Amines;

1987
Dose-dependent effects of deprenyl on CSF monoamine metabolites in patients with Alzheimer's disease.
    Psychopharmacology, 1987, Volume: 91, Issue:3

    Topics: Aging; Alzheimer Disease; Biogenic Amines; Dose-Response Relationship, Drug; Homovanillic Acid; Huma

1987
Clinical and biochemical correlates of bradyphrenia in Parkinson's disease.
    Neurology, 1987, Volume: 37, Issue:7

    Topics: Aged; Alzheimer Disease; Arousal; Attention; Biogenic Amines; Cognition Disorders; Homovanillic Acid

1987
Monoamines and their metabolites in cerebrospinal fluid of patients with senile dementia of Alzheimer type using high performance liquid chromatography and gas chromatography-mass spectrometry.
    Acta psychiatrica Scandinavica, 1987, Volume: 75, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biogenic Amines; Chromatography, High Pressure Liquid; G

1987
Alzheimer-like neurotransmitter deficits in adult Down's syndrome brain tissue.
    Journal of neurology, neurosurgery, and psychiatry, 1987, Volume: 50, Issue:6

    Topics: Acetylcholine; Adult; Age Factors; Alzheimer Disease; Brain; Choline O-Acetyltransferase; Dopamine;

1987
The effects of antidepressants on the cerebrospinal fluid homovanillic acid/5-hydroxyindoleacetic acid ratio.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:5

    Topics: Alzheimer Disease; Antidepressive Agents; Cerebrospinal Fluid; Depressive Disorder; Drug Evaluation;

1987
Neuropsychological test performance and CSF levels of monoamine metabolites in healthy volunteers and patients with Alzheimer's dementia.
    Acta psychiatrica Scandinavica, 1987, Volume: 76, Issue:6

    Topics: Aged; Alzheimer Disease; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

1987
Cerebrospinal fluid monoamine markers are decreased in dementia of the Alzheimer type with extrapyramidal features.
    Neurology, 1988, Volume: 38, Issue:4

    Topics: Aged; Alzheimer Disease; Biopterins; Dementia; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti

1988
Simultaneous determination of four monoamine metabolites and serotonin in cerebrospinal fluid by "high-performance" liquid chromatography with electrochemical detection; application for patients with Alzheimer's disease.
    Clinical chemistry, 1988, Volume: 34, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Electrochem

1988
Possible neurotransmitter basis of behavioral changes in Alzheimer's disease.
    Annals of neurology, 1988, Volume: 23, Issue:6

    Topics: Acetylcholine; Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; gamma-Aminobutyric Acid;

1988
Selective attention in Alzheimer's disease: CSF correlates of behavioral impairments.
    Neuropsychologia, 1988, Volume: 26, Issue:6

    Topics: Aged; Alzheimer Disease; Attention; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic

1988
Cerebrospinal fluid neurochemistry in the myoclonic subtype of Alzheimer's disease.
    Annals of neurology, 1988, Volume: 24, Issue:5

    Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Analysis of Variance; Biopterins; Female; Homovanilli

1988
Vasopressin levels in CSF of Alzheimer patients: correlations with monoamine metabolites and neuropsychological test performance.
    Psychoneuroendocrinology, 1989, Volume: 14, Issue:1-2

    Topics: Aged; Alzheimer Disease; Arginine Vasopressin; Female; Glycols; Homovanillic Acid; Humans; Hydroxyin

1989
Monoamine metabolites in cerebrospinal fluid and behavioral ratings in patients with early and late onset of Alzheimer dementia.
    Alzheimer disease and associated disorders, 1989,Fall, Volume: 3, Issue:3

    Topics: Aged; Alzheimer Disease; Behavior; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic A

1989
CSF corticotropin-releasing factor (CRF) in Alzheimer's disease: its relationship to severity of dementia and monoamine metabolites.
    Biological psychiatry, 1989, Volume: 26, Issue:5

    Topics: Aged; Alzheimer Disease; Corticotropin-Releasing Hormone; Disability Evaluation; Female; Homovanilli

1989
Neurotransmitters in the brains of patients with dementia disorders.
    Danish medical bulletin, 1985, Volume: 32 Suppl 1

    Topics: Acetylcholine; Aged; Alzheimer Disease; Brain; Choline O-Acetyltransferase; Dementia; Dopamine; Glut

1985
CSF monoamine metabolite levels in Alzheimer's and Parkinson's disease.
    Archives of neurology, 1985, Volume: 42, Issue:5

    Topics: Adult; Aged; Alzheimer Disease; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid

1985
[Clinical significance of homovanillic acid analysis in endocrine tests of the adrenal medulla and sympathetic nervous system].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 48 Suppl

    Topics: Adrenal Medulla; Alzheimer Disease; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans;

1989
[Ageing and neurotransmitters].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1985, Volume: 74, Issue:10

    Topics: Acetylcholine; Aged; Aging; Alzheimer Disease; Animals; Brain; Choline O-Acetyltransferase; Dopamine

1985
Catecholamine metabolites and cyclic nucleotides in cerebrospinal fluid in dementia of Alzheimer type.
    Journal of gerontology, 1985, Volume: 40, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Alzheimer Disease; Catecholamines; Cyclic AMP; Cyclic GMP; Hom

1985
Cerebrospinal fluid levels of angiotensin-converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson's disease: a correlative study.
    Biological psychiatry, 1986, Volume: 21, Issue:14

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholinesterase; Aged; Alzheimer Disease; Cerebrospinal Fluid P

1986
Catecholaminergic neurones assessed ante-mortem in Alzheimer's disease.
    Brain research, 1987, Jun-30, Volume: 414, Issue:2

    Topics: Adult; Aged; Alzheimer Disease; Catecholamines; Cerebral Cortex; Choline O-Acetyltransferase; Cognit

1987