Page last updated: 2024-10-21

homovanillic acid and Alcohol Abuse

homovanillic acid has been researched along with Alcohol Abuse in 85 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Research Excerpts

ExcerptRelevanceReference
" After chronic alcoholism, there was a decrease in the ratio of dihydroxyphenylacetic acid (DOPA) and homovanillic acid (HVA) to dopamine in the nucleus accumbens and striatum in rats subjected to alcoholism, as compared with intact controls."3.72Mechanisms of the influences of the central administration of substance P on ethanol consumption in chronically alcoholic rats. ( Bychkov, ER; Dambinova, SA; Lebedev, AA; Nikolaev, SV, 2003)
"Among treatment-seeking alcoholics, early age at onset is generally associated with a more severe course of alcoholism and lower cerebrospinal fluid 5-hydroxyindoleacetic acid concentration."3.69Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics. ( Brown, GL; Eckardt, MJ; Fils-Aime, ML; George, DT; Linnoila, M; Mefford, I, 1996)
"Among all offenders, low cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) concentrations were associated with a family history positive for paternal alcoholism with violence."3.69A prospective follow-up study of alcoholic violent offenders and fire setters. ( Eggert, M; Linnoila, M; Rawlings, R; Virkkunen, M, 1996)
" There were significant, negative correlations between interview-derived lifetime aggression scores and cerebrospinal fluid concentrations of both the serotonin metabolite 5-hydroxyindoleacetic acid and the dopamine metabolite homovanillic acid."3.68Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls. ( Adinoff, B; Goldman, D; Lamparski, D; Limson, R; Linnoila, M; Ravitz, B; Roy, A, 1991)
" Recidivists who committed a new violent offense or arson had significantly lower cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid concentrations and blood glucose nadirs after oral glucose challenge than did nonrecidivists."3.67Relationship of psychobiological variables to recidivism in violent offenders and impulsive fire setters. A follow-up study. ( Bartko, J; De Jong, J; Goodwin, FK; Linnoila, M; Virkkunen, M, 1989)
"5-Hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were measured in the spinal fluid of 45 women hospitalized in a psychiatric department for major depression (14 cases), schizophrenia (18 cases) and alcohol dependence (13 cases)."3.66Relationship between cerebrospinal fluid amine metabolites, neuroendocrine findings and personality dimensions (Marke-Nyman scale factors) in psychiatric patients. ( Arató, M; Banki, CM, 1983)
"5-Hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were measured in the lumbar cerebrospinal fluid of 57 drug-free female patients with DSM-III diagnoses of major unipolar or bipolar depression (n = 14), schizophrenic disorder (n = 18), alcohol dependence (n = 13) and a group of other disorders (n = 12)."3.66Amine metabolites and neuroendocrine responses related to depression and suicide. ( Arató, M; Banki, CM, 1983)
"Alcoholic, impulsive offenders with antisocial personality disorder had low mean cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5-HIAA) and corticotropin levels and high mean CSF testosterone concentrations."1.29CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. ( Bissette, G; Guidotti, A; Kalogeras, K; Karonen, SL; Linnoila, M; Nemeroff, C; Poland, RE; Rawlings, R; Tokola, R; Virkkunen, M, 1994)
"To explore dopaminergic mechanisms in alcohol dependence, the authors measured plasma homovanillic acid (HVA) in recently detoxified alcohol-dependent men."1.29Low plasma homovanillic acid levels in recently abstinent alcoholic men. ( Chae, Y; Fulton, MK; Isbell, PG; Kramer, G; Moeller, FG; Petty, F, 1995)
" Dose-response curves for DA and 5-HT release indicated no marked difference in the sensitivity to ethanol between the lines."1.28Ethanol enhances the release of dopamine and serotonin in the nucleus accumbens of HAD and LAD lines of rats. ( Li, TK; Lumeng, L; McBride, WJ; Yoshimoto, K, 1992)
"Severity of withdrawal symptoms assessed on a rating scale in 14 patients with 4 days or less of abstinence correlated marginally with HVA but not with 5-HIAA."1.26Factors influencing monoamine metabolites and tryptophan in patients with alcohol dependence. ( Banki, CM, 1981)

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-199035 (41.18)18.7374
1990's33 (38.82)18.2507
2000's16 (18.82)29.6817
2010's1 (1.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirth, N1
Meinhardt, MW1
Noori, HR1
Salgado, H1
Torres-Ramirez, O1
Uhrig, S1
Broccoli, L1
Vengeliene, V1
Roßmanith, M1
Perreau-Lenz, S1
Köhr, G1
Sommer, WH1
Spanagel, R1
Hansson, AC1
Yoshimura, R1
Nakano, W1
Nakamura, K1
Heinz, A1
Jones, DW1
Bissette, G3
Hommer, D1
Ragan, P1
Knable, M1
Wellek, S1
Linnoila, M22
Weinberger, DR1
Nikolaev, SV2
Bychkov, ER2
Lebedev, AA2
Dambinova, SA2
Sher, L4
Agartz, I1
Shoaf, S1
Rawlings, RR1
Momenan, R1
Hommer, DW1
Köhnke, MD3
Wiatr, G3
Kolb, W3
Köhnke, AM1
Schick, S1
Lutz, U2
Vonthein, R1
Gaertner, I1
Ojanen, S1
Koistinen, M1
Bäckström, P1
Kankaanpää, A1
Tuomainen, P1
Hyytiä, P1
Kiianmaa, K1
Oquendo, MA2
Li, S1
Huang, YY2
Grunebaum, MF2
Burke, AK2
Malone, KM1
Mann, JJ2
Ponce, G1
Hoenicka, J1
Rodríguez-Jiménez, R1
Gozalo, A1
Jimenéz, M1
Monasor, R1
Aragüés, M1
Rubio, G1
Jiménez-Arriero, MA1
Ramos, JA1
Palomo, T1
Ducci, F1
Newman, TK1
Funt, S1
Brown, GL5
Virkkunen, M8
Goldman, D6
Maurer, S2
Batra, A2
Lutz, UC1
Machicao, F1
Buchkremer, G1
Quintanilla, ME1
Bustamante, D1
Tampier, L1
Israel, Y1
Herrera-Marschitz, M1
Zarcone, VP1
Schreier, L2
Mitchell, G1
Orenberg, E2
Barchas, J2
Carlsson, A1
Adolfsson, R1
Aquilonius, SM1
Gottfries, CG1
Oreland, L1
Svennerholm, L1
Winblad, B3
Fujimoto, A1
Rosenthal, NE1
Davenport, Y1
Cowdry, RW1
Webster, MH1
Goodwin, FK4
Banki, CM6
Molnar, G1
Arató, M4
Papp, Z2
Kurcz, M1
Sjöquist, B4
Perdahl, E1
Murphy, JM2
McBride, WJ3
Lumeng, L3
Li, TK3
Martin, PR1
Ebert, MH1
Gordon, EK1
Kopin, IJ1
Borg, S2
Robins, AH1
Barron, JL1
Eriksson, A1
Kvande, H1
Rawlings, R5
Tokola, R2
Poland, RE1
Guidotti, A2
Nemeroff, C1
Kalogeras, K1
Karonen, SL1
Hartleb, J1
Eue, S1
Kemper, A1
George, T2
Eckardt, M1
Higley, JD3
Nielsen, D1
Sano, H2
Suzuki, Y2
Ohara, K4
Miyasato, K1
Yokoyama, T2
Adamson, MD1
Kennedy, J1
Petronis, A1
Dean, M2
Blanchard, BA1
Glick, SD1
Hawley, RJ1
Nemeroff, CB1
Gabel, S1
Stadler, J1
Bjorn, J1
Shindledecker, R1
Bowden, CL1
Fulton, MK1
Kramer, G1
Moeller, FG1
Chae, Y1
Isbell, PG1
Petty, F1
Fils-Aime, ML1
Eckardt, MJ2
George, DT5
Mefford, I1
Eggert, M1
Howard, MO1
Cowley, DS1
Roy-Byrne, PP1
Hopfenbeck, JR1
Suomi, SJ2
Moss, HB1
Yao, JK1
Lambert, G1
Esler, M1
Philpot, RM1
Kirstein, CL1
Hibbeln, JR1
Umhau, JC1
Salem, N1
Phillips, MJ1
Shoaf, SE1
Petrakis, IL1
Trevisan, L1
D'Souza, C1
Gil, R1
Krasnicki, S1
Webb, E1
Heninger, G1
Cooney, N1
Krystal, JH1
Lappalainen, J1
Long, JC1
Ozaki, N1
Zarcone, V1
Benson, K1
Kato, N2
Takahashi, S2
Tani, N2
Iwase, N1
Odani, K1
Terenius, L1
Wahlström, A1
Agren, H1
Ballenger, JC2
Major, LF2
Zoghbi, F1
Emerit, J1
Fermanian, J1
Bousquet, O1
Legrand, JC1
Mazzella, GL1
Bo, P1
Mola, M1
Massarini, M1
Gitlow, SE1
Dziedzic, LM1
Dziedzic, SW1
Wong, BL1
Bolos, AM1
Diana, M2
Gessa, GL3
Rossetti, ZL2
Yazaki, R1
Ishigaki, T1
Yoshimoto, K1
Melis, F1
Carboni, S1
Roy, A5
Lamparski, D3
De Jong, J3
Adinoff, B5
Ravitz, B3
Nutt, D1
Nutt, DJ1
Berrettini, W1
Mefford, IN1
Costa, E1
Limson, R1
Wahlström, G1
Magnusson, O1
Nordberg, A1
Stenström, A1
Tiger, G1
DeJong, J2
Fadda, F1
Colombo, G1
Degrell, I1
Pék, G1
Nagy, D1
Nagy, E1
Hoyer, S1
Bartko, J1
Lidberg, L1
Tuck, JR1
Asberg, M1
Scalia-Tomba, GP1
Bertilsson, L1
Oliver, J1
Potter, WZ1
Varkov, AI1
Malikova, LA1
Yamane, H1
Kondo, H1
Angrist, B1
Sathananthan, G1
Wilk, S1
Gershon, S1
Roos, BE1
Silfverskiöld, BP1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind, Placebo-Controlled Study of Brexpiprazole in the Treatment of Borderline Personality Disorder.[NCT03418675]Phase 280 participants (Actual)Interventional2018-11-26Completed
The Better Resiliency Among Veterans With Omega-3's (BRAVO) Study: A Double Blind, Placebo-Controlled Trial of Omega-3 Fatty Acid Supplementation Among Military Veterans[NCT01901887]Phase 1125 participants (Actual)Interventional2014-03-01Terminated (stopped due to low recruitment)
Ranger Resilience and Improved Performance on Phospholipid Bound Omega-3's[NCT02908932]555 participants (Actual)Interventional2016-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Hamilton Anxiety Rating Scale (HAM-A)

A clinician-administered assessment of anxiety that will be assessed at all study visits (Visit 1-Visit 8). Changes in scores from baseline to final visit will be assessed. Higher scores (up to 56) indicate higher levels of anxiety, with 0 being no symptoms of anxiety. (NCT03418675)
Timeframe: assessed at Visits 1 to 8, change in scores from Visit 1 to Visit 8 (baseline to Week 12) is reported

Interventionchange in score on a scale (Mean)
Placebo-2.41
Rexulti-4.88

Hamilton Depression Rating Scale (HAM-D)

A clinician-administered assessment of depression that will be assessed at all study visits (Visits 1-8). Higher total scores indicate higher levels of depression (up to 52), while a score of 0 would indicate no depressive symptoms. (NCT03418675)
Timeframe: Assessed at Visits 1 to 8, change in scores from Visit 1 to Visit 8 (baseline to week 12) is reported

Interventionchange in score on a scale (Mean)
Placebo-2.09
Rexulti-3.81

Barratt Impulsiveness Scale (BIS)

A self-report assessment of impulsivity that will be assessed at baseline and visit 8. The BIS is composed of 30 items describing common impulsive or non-impulsive (for reverse scored items) behaviors and preferences. Items are scored on a 4-point scale: (Rarely/Never = 1, Occasionally = 2, Often = 3, Almost Always/Always = 4). These scores are summed to produce an overall impulsivity score ranging from 30 (not impulsive) to 120 (extremely impulsive). (NCT03418675)
Timeframe: Baseline (Visit 1), Week 12 (Visit 8)

,
Interventionscore on a scale (Mean)
Visit 1Visit 8
Placebo76.5368.13
Rexulti72.2770.5

Borderline Evaluation of Severity Over Time (BEST)

A self rated scale used to measure severity and change. The first 12 items of the scale are on a scale from 1-5, with 5 meaning that the item caused extreme distress, severe difficulties in relationships, and/or kept them from getting things done. The lowest rating (1) means it caused little or no problems. Items 13-15 (positive behaviors) are rated according to frequency. Completed at every visit. (NCT03418675)
Timeframe: Assessed at Visits 1 to 8, change in scores from Visit 1 to Visit 8 (baseline to week 12) is reported

,
Interventionscore on a scale (Mean)
Visit 1Visit 8
Placebo40.9029.15
Rexulti40.5423.15

Columbia Suicide Severity Rating Scale (CSSRS)

"A self-report scale measuring suicidality. Subjects will complete the scale at all visits. Subjects are asked about suicidal thoughts. If answers are no, rater can proceed to suicidal behavior section where subject is asked about any non-suicidal self injurious behavior. If yes, subject is asked about intensity of ideations. In the event of serious threat to themselves, the subject will be escorted to the emergency room. Total score indicates severity of suicidal ideation and behavior, with lower scores representing lower levels of suicidality and higher scores representing higher levels of suicidality. A score of 0 would reflect no suicidality present, whereas a maximum score of 5 would reflect active suicidal ideation with intent to act." (NCT03418675)
Timeframe: Baseline (Visit 1), Week 12 (Visit 8)

,
Interventionscore on a scale (Mean)
Visit 1Visit 8
Placebo1.150.23
Rexulti0.730.08

MINI International Neuropsychiatric Interview

A short-structured interview that assesses comorbid psychiatric disorders according to the DSM 5 criteria. This assessment will be done during the baseline visit. (NCT03418675)
Timeframe: Baseline (Week 1)

,
InterventionParticipants (Count of Participants)
Major Depressive Episode (Current)Major Depressive Episode (Past)Manic Episode (Current)Manic Episode (Past)Hypomanic Episode (Current)Bipolar I Disorder (Current)Bipolar I Disorder (Past)Bipolar II Disorder (Current)Bipolar II Disorder (Past)Panic Disorder (Current)Panic Disorder (Lifetime)Agoraphobia (Current)Social Anxiety Disorder (Current)Obsessive Compulsive Disorder (Current)Post Traumatic Stress Disorder (Current)Alcohol Use Disorder (Past 12 months)Substance Use Disorder (Past 12 months)Any Psychotic Disorder (Current)Any Psychotic Disorder (Lifetime)Major Depressive Disorder with Psychotic Features (Current)Major Depressive Disorder with Psychotic Features (Past)Anorexia Nervosa (current)Bulimia Nervosa (Current)Binge Eating Disorder (Current)Generalized Anxiety Disorder (Current)Antisocial Personality Disorder (Lifetime)ADHD Combined Type (Current)ADHD Inattentive Type (Current)ADHD Hyperactive Type (Current)Tourette's Syndrome (Lifetime)Persistent Motor Tic Disorder (Lifetime)Provisional Vocal Tic Disorder (Lifetime)Provisional Tic Disorder (Lifetime)Specific PhobiaBody Dysmorphic Disorder (Current)
Placebo16122110000611763913110000042108201010043
Rexulti1818230000161099312880100144154411110012

Quality of Life Inventory (QOLI)

A self-report assessment of patient perceived quality of life that will be assessed at baseline and visit 8. Higher scores indicate a higher quality of life, whereas lower scores indicate a lower quality of life. Participants are asked to rate the importance of each domain on a 3-point scale ranging from 1=not important to 3=very important, and to rate how satisfied they are with that domain on a 6-point scale, ranging from -3=very dissatisfied to +3=very satisfied. In scoring, importance ratings are multiplied by satisfaction ratings to produce weighted satisfaction scores for each of the 16 domains. Weighted satisfaction scores are summed and divided by the number of domains that were rated as important or very important to produce a raw score, which is then converted to a t-score, which provides a proxy measurement for perceived quality of life. T-scores range from very low perceived quality of life (0-36) to high perceived quality of life (58-77). (NCT03418675)
Timeframe: Baseline (Week 1), Week 12 (Visit 8)

,
Interventionscore on a scale (Mean)
Visit 1Visit 8
Placebo28.8930.75
Rexulti28.7035.71

Self Report Version of Zanarini Scale

A self-report scale assessing Borderline Personality severity that will be assessed at all visits.This scale is assessing severity and change in BPD symptoms. This is a 9-item scale measuring severity of different aspects of Borderline Personality Disorder, with each item rated on a 0-4 scale, 0=no symptoms, 4=severe symptoms. Total scores range from 0-36. (NCT03418675)
Timeframe: Baseline (Visit 1), Week 1 (Visit 2), Week 2 (Visit 3), Week 4 (Visit 4), Week 6 (Visit 5), Week 8 (Visit 6), Week 10 (Visit 7), Week 12 (Visit 8)

,
Interventionscore on a scale (Mean)
Visit 1Visit 2Visit 3Visit 4Visit 5Visit 6Visit 7Visit 8
Placebo18.212.810.710.79.79.68.79.3
Rexulti17.610.97.98.07.06.66.05.8

Sheehan Disability Scale (SDS)

Subjects will complete the SDS at all visits. The change in scores from baseline to study completion will be assessed. The scale itself assesses the level of disability from borderline personality disorder (or target disorder) with higher scores indicating a more debilitating disorder. Scores range from 0-30. (NCT03418675)
Timeframe: Baseline (Visit 1), Week 1 (Visit 2), Week 2 (Visit 3), Week 4 (Visit 4), Week 6 (Visit 5), Week 8 (Visit 6), Week 10 (Visit 7), Week 12 (Visit 8)

,
Interventionscore on a scale (Mean)
Visit 1Visit 2Visit 3Visit 4Visit 5Visit 6Visit 7Visit 8
Placebo17.313.311.512.411.711.212.012.7
Rexulti15.810.77.87.87.07.96.97.7

Symptom Checklist-90 Revised

An instrument that helps evaluate a broad range of psychological problems and symptoms of Borderline Personality Disorder psychopathology. This will be assessed at baseline and visit 8.The 115 items are rated by using a 5-step Likert scale (0=not at all, 4=very strong) and provide a global picture of borderline psychopathology. Global scores of borderline psychopathology are calculated by summing 12 items and range from 0-48. Higher scores indicate more severe symptoms of Borderline Personality Disorder. (NCT03418675)
Timeframe: Baseline, Visit 8 (Week 12)

,
Interventionscore on a scale (Mean)
Visit 1Visit 8
Placebo26.1720.25
Rexulti25.4214.21

Zanarini Rating Scale for Borderline Personality Disorder

A clinician-administered scale assessing Borderline Personality Scale severity at all study visits. Scores range from 0-36. Higher scores represent worse Borderline Personality Disorder severity, and lower scores represent milder Borderline Personality Disorder severity. (NCT03418675)
Timeframe: Baseline (Visit 1), Week 1 (Visit 2), Week 2 (Visit 3), Week 4 (Visit 4), Week 6 (Visit 5), Week 8 (Visit 6), Week 10 (Visit 7), Week 12 (Visit 8)

,
Interventionscore on a scale (Mean)
Visit 1Visit 2Visit 3Visit 4Visit 5Visit 6Visit 7Visit 8
Placebo14.97.64.764.25.758.4
Rexulti14.96.75.34.44.54.943.1

Reviews

2 reviews available for homovanillic acid and Alcohol Abuse

ArticleYear
Serotonin, violent behavior and alcohol.
    EXS, 1994, Volume: 71

    Topics: Age Factors; Alcoholism; Animals; Biomarkers; Finland; Homovanillic Acid; Humans; Hydroxyindoleaceti

1994
Alcoholism and suicide.
    Suicide & life-threatening behavior, 1986,Summer, Volume: 16, Issue:2

    Topics: Adult; Age Factors; Alcoholism; Depressive Disorder; Female; Glucose; Homovanillic Acid; Humans; Hyd

1986

Trials

3 trials available for homovanillic acid and Alcohol Abuse

ArticleYear
Effects of clonidine on central and peripheral catecholamine metabolism.
    Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:3

    Topics: Aged; Alcoholism; Blood Pressure; Clonidine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Ma

1984
The effect of disulfiram on the urinary excretion of catecholamine metabolites in alcoholic males.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1983, Jan-08, Volume: 63, Issue:2

    Topics: Adult; Alcoholism; Disulfiram; Epinephrine; Homovanillic Acid; Humans; Male; Metanephrine; Middle Ag

1983
Buspirone treatment of alcoholism: age of onset, and cerebrospinal fluid 5-hydroxyindolacetic acid and homovanillic acid concentrations, but not medication treatment, predict return to drinking.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:2

    Topics: Adult; Age of Onset; Alcoholism; Anti-Anxiety Agents; Buspirone; Double-Blind Method; Homovanillic A

1999

Other Studies

80 other studies available for homovanillic acid and Alcohol Abuse

ArticleYear
Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, Mar-15, Volume: 113, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Alcohol Abstinence; Alcoholism; Animals; Benzazepines;

2016
[Alcoholism and depression: catecholamines and brain-derived neurotrophic factors].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2009, Volume: 111, Issue:7

    Topics: Adult; Aged; Alcoholism; Antidepressive Agents; Biomarkers; Brain-Derived Neurotrophic Factor; Catec

2009
Relationship between cortisol and serotonin metabolites and transporters in alcoholism [correction of alcolholism].
    Pharmacopsychiatry, 2002, Volume: 35, Issue:4

    Topics: Adult; Affect; Alcoholism; Carrier Proteins; Case-Control Studies; Corticotropin-Releasing Hormone;

2002
[The influence of substance P central administration on ethanol intake in rats chronically exposed to alcohol].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2002, Volume: 88, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Corpus Striatum; Dopamine; Dr

2002
Alcoholism, violence, and CSF HVA. Cerebrospinal fluid homovanillic acid.
    Acta psychiatrica Scandinavica, 2003, Volume: 107, Issue:1

    Topics: Alcoholism; Homovanillic Acid; Humans; Violence

2003
CSF monoamine metabolites and MRI brain volumes in alcohol dependence.
    Psychiatry research, 2003, Jan-20, Volume: 122, Issue:1

    Topics: Adult; Alcoholism; Biogenic Monoamines; Brain; Female; Homovanillic Acid; Humans; Magnetic Resonance

2003
Plasma homovanillic acid: a significant association with alcoholism is independent of a functional polymorphism of the human catechol-O-methyltransferase gene.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:5

    Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Analysis of Variance; Catechol O-Methyltransferase;

2003
Differential behavioural sensitization to intermittent morphine treatment in alcohol-preferring AA and alcohol-avoiding ANA rats: role of mesolimbic dopamine.
    The European journal of neuroscience, 2003, Volume: 17, Issue:8

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Chromatography, High Pressure Liquid; Dopamine;

2003
Lower CSF homovanillic acid levels in depressed patients with a history of alcoholism.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:9

    Topics: Adult; Alcoholism; Case-Control Studies; Chi-Square Distribution; Chromatography, High Pressure Liqu

2003
Major depressive disorder and a past history of alcoholism.
    The Australian and New Zealand journal of psychiatry, 2003, Volume: 37, Issue:6

    Topics: Alcoholism; Comorbidity; Depressive Disorder, Major; Homovanillic Acid; Humans

2003
Mechanisms of the influences of the central administration of substance P on ethanol consumption in chronically alcoholic rats.
    Neuroscience and behavioral physiology, 2003, Volume: 33, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Homovanill

2003
IDRD2 TaqIA polymorphism is associated with urinary homovanillic acid levels in a sample of Spanish male alcoholic patients.
    Neurotoxicity research, 2004, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Aged; Alcoholism; Alleles; Biogenic Monoamines; Chromatography, High Pressure Liq

2004
CSF monoamine metabolites and lethality of suicide attempts in depressed patients with alcohol dependence.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2007, Volume: 17, Issue:1

    Topics: Adult; Alcoholism; Biogenic Monoamines; Depression; Female; Homovanillic Acid; Humans; Hydroxyindole

2007
A functional polymorphism in the MAOA gene promoter (MAOA-LPR) predicts central dopamine function and body mass index.
    Molecular psychiatry, 2006, Volume: 11, Issue:9

    Topics: Alcoholism; Body Mass Index; Crime; Dopamine; Finland; Genotype; Homovanillic Acid; Humans; Hydroxyi

2006
Allele distribution of a monoamine oxidase A gene promoter polymorphism in German alcoholics and in subgroups with severe forms of alcohol withdrawal and its influence on plasma homovanillic acid.
    Psychiatric genetics, 2006, Volume: 16, Issue:6

    Topics: Alcoholism; Alleles; Germany; Homovanillic Acid; Humans; Monoamine Oxidase; Promoter Regions, Geneti

2006
Significant impact of MTHFR C677T polymorphism on plasma homovanillic acid (HVA) levels among alcohol-dependent patients.
    Addiction biology, 2007, Volume: 12, Issue:1

    Topics: Adult; Alcoholism; Alleles; Dopamine; Female; Genetic Carrier Screening; Genotype; Homocysteine; Hom

2007
Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol.
    European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Anesthesia, Inhalation; Animals; Breed

2007
Sleep variables, cyclic AMP and biogenic amine metabolites after one day of ethanol ingestion.
    Journal of studies on alcohol, 1980, Volume: 41, Issue:3

    Topics: Adult; Alcohol Drinking; Alcoholism; Cyclic AMP; Ethanol; Homovanillic Acid; Humans; Hydroxyindoleac

1980
Biogenic amines in human brain in normal aging, senile dementia, and chronic alcoholism.
    Advances in biochemical psychopharmacology, 1980, Volume: 23

    Topics: 5-Methoxytryptamine; Adult; Aged; Aging; Alcoholism; Brain; Dementia; Dopamine; Homovanillic Acid; H

1980
[Cerebrospinal fluid monamine metabolites and cyclic nucleotides during alcoholic withdrawal syndrome].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1980, Volume: 82, Issue:5

    Topics: Adult; Alcoholism; Brain; Cyclic AMP; Cyclic GMP; Female; Homovanillic Acid; Humans; Hydroxyindoleac

1980
Monoamine metabolites in cerebrospinal fluid of depressive subgroups.
    Psychiatry research, 1980, Volume: 2, Issue:1

    Topics: Adult; Alcoholism; Bipolar Disorder; Depressive Disorder; Female; Glycols; Homovanillic Acid; Humans

1980
Factors influencing monoamine metabolites and tryptophan in patients with alcohol dependence.
    Journal of neural transmission, 1981, Volume: 50, Issue:2-4

    Topics: Alcoholism; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Phenylacetates; R

1981
The influence of age, height, and body weight on cerebrospinal fluid amine metabolites and tryptophan in women.
    Biological psychiatry, 1981, Volume: 16, Issue:8

    Topics: Adult; Age Factors; Alcoholism; Body Height; Body Weight; Depressive Disorder; Female; Homovanillic

1981
Relationship between cerebrospinal fluid amine metabolites, neuroendocrine findings and personality dimensions (Marke-Nyman scale factors) in psychiatric patients.
    Acta psychiatrica Scandinavica, 1983, Volume: 67, Issue:4

    Topics: Alcoholism; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans;

1983
Amine metabolites and neuroendocrine responses related to depression and suicide.
    Journal of affective disorders, 1983, Volume: 5, Issue:3

    Topics: Alcoholism; Depression; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; Hydro

1983
The effect of dexamethasone on cerebrospinal fluid monoamine metabolites and cortisol in psychiatric patients.
    Pharmacopsychiatria, 1983, Volume: 16, Issue:3

    Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Homovanillic

1983
Cerebrospinal fluid biochemical examinations: do they reflect clinical or biological differences?
    Biological psychiatry, 1983, Volume: 18, Issue:9

    Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Calcium; Depressive Disorder; Dexamethasone; Female; Homo

1983
The effect of alcoholism on salsolinol and biogenic amines in human brain.
    Drug and alcohol dependence, 1983, Volume: 12, Issue:1

    Topics: Alcoholism; Biogenic Amines; Brain; Caudate Nucleus; Dopamine; Homovanillic Acid; Humans; Hydroxyind

1983
Monoamine and metabolite levels in CNS regions of the P line of alcohol-preferring rats after acute and chronic ethanol treatment.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholic Intoxication; Alcoholism; Animals; Brain Chemistry; Choice

1983
Catecholamines and metabolites in cerebrospinal fluid of teetotallers and sober alcoholics.
    Drug and alcohol dependence, 1984, Volume: 13, Issue:4

    Topics: Adult; Age Factors; Alcohol Drinking; Alcoholism; Catecholamines; Dopamine; Homovanillic Acid; Human

1984
Salsolinol and catecholamines in human brain and their relation to alcoholism.
    Progress in clinical and biological research, 1982, Volume: 90

    Topics: Adult; Alcoholism; Animals; Autopsy; Brain; Brain Chemistry; Catecholamines; Dopamine; Homovanillic

1982
Catecholamine derived compounds in urine and cerebrospinal fluid from alcoholics during and after long-standing intoxication.
    Substance and alcohol actions/misuse, 1981, Volume: 2, Issue:1

    Topics: Adult; Aged; Alcoholic Intoxication; Alcoholism; Catecholamines; Dopamine; Female; Homovanillic Acid

1981
CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers.
    Archives of general psychiatry, 1994, Volume: 51, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Alcoholism; Antisocial Personality Disorder; Circadian Rhythm; D

1994
Simultaneous analysis of homovanillic acid, 5-hydroxyindoleacetic acid, 3-methoxy-4-hydroxyphenylethylene glycol and vanilmandelic acid in plasma from alcoholics by high-performance liquid chromatography with electrochemical detection. Critical comparison
    Journal of chromatography, 1993, Dec-22, Volume: 622, Issue:2

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Biogenic Monoamines; Chromatography, High Pressure Liquid;

1993
Circadian variations in plasma monoamine metabolites level in alcoholic patients: a possible predictor of alcohol withdrawal delirium.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:4

    Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Analysis of Variance; Biogenic Monoamines; Circadian

1994
DRD4 dopamine receptor genotype and CSF monoamine metabolites in Finnish alcoholics and controls.
    American journal of medical genetics, 1995, Jun-19, Volume: 60, Issue:3

    Topics: Adult; Alcoholism; Alleles; Amines; Base Sequence; Finland; Homovanillic Acid; Humans; Male; Molecul

1995
Sex differences in mesolimbic dopamine responses to ethanol and relationship to ethanol intake in rats.
    Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism, 1995, Volume: 12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Arousal; Corpus Striatum; Dos

1995
Neurochemical correlates of sympathetic activation during severe alcohol withdrawal.
    Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:6

    Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Arousal; Carrier Proteins; Corticotropin-Relea

1994
Monoamine oxidase and homovanillic acid in boys with predispositions to substance abuse.
    Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:5

    Topics: Adolescent; Alcoholism; Antisocial Personality Disorder; Child; Child of Impaired Parents; Fathers;

1994
Low plasma homovanillic acid levels in recently abstinent alcoholic men.
    The American journal of psychiatry, 1995, Volume: 152, Issue:12

    Topics: Alcohol Drinking; Alcoholism; Dopamine; Homovanillic Acid; Hospitalization; Humans; Male; Sensitivit

1995
Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics.
    Archives of general psychiatry, 1996, Volume: 53, Issue:3

    Topics: Adult; Age of Onset; Alcohol Drinking; Alcoholism; Comorbidity; Family; Female; Homovanillic Acid; H

1996
A prospective follow-up study of alcoholic violent offenders and fire setters.
    Archives of general psychiatry, 1996, Volume: 53, Issue:6

    Topics: Adult; Alcoholism; Cholesterol; Comorbidity; Criminal Law; Family; Finland; Firesetting Behavior; Fo

1996
Tridimensional personality traits in sons of alcoholic and nonalcoholic fathers.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:3

    Topics: Adult; Alcoholism; Arousal; Blood Platelets; Child of Impaired Parents; Homovanillic Acid; Humans; M

1996
A nonhuman primate model of type II excessive alcohol consumption? Part 1. Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations and diminished social competence correlate with excessive alcohol consumption.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:4

    Topics: Adult; Affect; Age Factors; Alcohol Drinking; Alcoholism; Animals; Arousal; Disease Models, Animal;

1996
A nonhuman primate model of type II alcoholism? Part 2. Diminished social competence and excessive aggression correlates with low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:4

    Topics: Adult; Age Factors; Aggression; Alcohol Drinking; Alcoholism; Animals; Antisocial Personality Disord

1996
Associations of beta-endorphin with HVA and MHPG in the plasma of prepubertal boys: effects of familial drug abuse and antisocial personality disorder liability.
    Psychiatry research, 1996, Jun-01, Volume: 62, Issue:3

    Topics: Alcoholism; Antisocial Personality Disorder; beta-Endorphin; Child; Child of Impaired Parents; Fathe

1996
Origin of homovanillic acid in plasma.
    The American journal of psychiatry, 1997, Volume: 154, Issue:1

    Topics: Alcoholism; Brain; Dopamine; Homovanillic Acid; Humans

1997
The effects of repeated alcohol exposure on the neurochemistry of the periadolescent nucleus accumbens septi.
    Neuroreport, 1998, May-11, Volume: 9, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alcoholism; Animals; Dopamine; Dose-Response Relationship, Dr

1998
Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics.
    Biological psychiatry, 1998, Aug-15, Volume: 44, Issue:4

    Topics: Adult; Age of Onset; Alcoholism; Biomarkers; Case-Control Studies; Cholesterol; Cross-Sectional Stud

1998
Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics.
    Biological psychiatry, 1998, Aug-15, Volume: 44, Issue:4

    Topics: Adult; Age of Onset; Alcoholism; Biomarkers; Case-Control Studies; Cholesterol; Cross-Sectional Stud

1998
Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics.
    Biological psychiatry, 1998, Aug-15, Volume: 44, Issue:4

    Topics: Adult; Age of Onset; Alcoholism; Biomarkers; Case-Control Studies; Cholesterol; Cross-Sectional Stud

1998
Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics.
    Biological psychiatry, 1998, Aug-15, Volume: 44, Issue:4

    Topics: Adult; Age of Onset; Alcoholism; Biomarkers; Case-Control Studies; Cholesterol; Cross-Sectional Stud

1998
CSF monoamine metabolite and beta endorphin levels in recently detoxified alcoholics and healthy controls: prediction of alcohol cue-induced craving?
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:8

    Topics: Adult; Alcoholism; Behavior, Addictive; Biogenic Monoamines; Biomarkers; Case-Control Studies; Ethan

1999
HTR2C Cys23Ser polymorphism in relation to CSF monoamine metabolite concentrations and DSM-III-R psychiatric diagnoses.
    Biological psychiatry, 1999, Sep-15, Volume: 46, Issue:6

    Topics: Alcoholism; Biogenic Monoamines; Brain; Dopamine; Genes; Genotype; Homovanillic Acid; Humans; Hydrox

1999
Alcohol, sleep and cerebrospinal fluid changes in alcoholics: cyclic AMP and biogenic amine metabolites in CSF.
    Advances in experimental medicine and biology, 1977, Volume: 85A

    Topics: Adult; Alcoholism; Biogenic Amines; Cyclic AMP; Ethanol; Homovanillic Acid; Humans; Hydroxyindoleace

1977
Changes in the metabolism of biogenic amines in alcoholism--especially regarding CSF monoamine metabolites and serum DBH activity.
    Alcoholism, clinical and experimental research, 1979, Volume: 3, Issue:1

    Topics: Adult; Aged; Alcoholism; Biogenic Amines; Dopamine beta-Hydroxylase; Female; Homovanillic Acid; Huma

1979
Naloxone (Narcan) treatment in depression: clinical observations and effects on CSF endorphins and monoamine metabolites.
    Psychopharmacology, 1977, Aug-31, Volume: 54, Issue:1

    Topics: Adult; Alcoholism; Biogenic Amines; Depression; Endorphins; Female; Homovanillic Acid; Humans; Hydro

1977
Alcohol and central serotonin metabolism in man.
    Archives of general psychiatry, 1979, Volume: 36, Issue:2

    Topics: Adult; Alcoholism; Brain; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middl

1979
Cerebrospinal fluid homovanillic acid in male alcoholics: effects of disulfiram.
    Biological psychiatry, 1977, Volume: 12, Issue:5

    Topics: Adult; Alcoholism; Disulfiram; Homovanillic Acid; Humans; Male; Middle Aged; Phenylacetates

1977
Comparative study of urinary excretion rates of para-hydroxy-mandelic acid, homovanillic acid, vanylmandelic acid in cirrhotic patients with and without encephalopathy.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Jan-31, Volume: 27, Issue:1

    Topics: Aged; Alcoholism; Female; Hepatic Encephalopathy; Homovanillic Acid; Humans; Hydroxy Acids; Liver Ci

1977
[Preliminary study of CSF levels of HVA in chronic alcoholics].
    Bollettino della Societa italiana di biologia sperimentale, 1976, Dec-30, Volume: 52, Issue:24

    Topics: Adult; Alcoholism; Brain; Catecholamines; Homovanillic Acid; Humans; Male; Middle Aged; Phenylacetat

1976
Influence of ethanol on human catecholamine metabolism.
    Annals of the New York Academy of Sciences, 1976, Volume: 273

    Topics: Adult; Alcoholism; Brain; Epinephrine; Ethanol; Homovanillic Acid; Humans; Male; Metanephrine; Middl

1976
D2 dopamine receptor genotype and cerebrospinal fluid homovanillic acid, 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol in alcoholics in Finland and the United States.
    Acta psychiatrica Scandinavica, 1992, Volume: 86, Issue:5

    Topics: Adult; Alcoholism; Alleles; Ethnicity; Finland; Genotype; Homovanillic Acid; Humans; Hydroxyindoleac

1992
Lack of tolerance to ethanol-induced stimulation of mesolimbic dopamine system.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1992, Volume: 27, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholic Intoxication; Alcoholism; Animals; Corpus Striatum; Dopami

1992
Circadian variation in plasma homovanillic acid level during and after alcohol withdrawal in alcoholic patients.
    Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:6

    Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Circadian Rhythm; Dopamine; Homovanillic Acid; Human

1992
Ethanol enhances the release of dopamine and serotonin in the nucleus accumbens of HAD and LAD lines of rats.
    Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Dopamine; Dose-Response Relationship, Drug; Eth

1992
Alcohol withdrawal in rats is associated with a marked fall in extraneuronal dopamine.
    Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Withdrawal Delirium; Alcoholism; Animals; Corpus Striatum; D

1992
Cerebrospinal fluid monoamine metabolites in alcoholic patients who attempt suicide.
    Acta psychiatrica Scandinavica, 1990, Volume: 81, Issue:1

    Topics: Adult; Alcoholism; Biogenic Monoamines; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxy

1990
A cerebrospinal fluid study of the pathophysiology of panic disorder associated with alcoholism.
    Acta psychiatrica Scandinavica, 1990, Volume: 82, Issue:1

    Topics: Adult; Alcoholism; Anxiety Disorders; beta-Endorphin; Diazepam Binding Inhibitor; Fear; Homovanillic

1990
Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls.
    Archives of general psychiatry, 1991, Volume: 48, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aggression; Alcoholism; Homovanillic Acid; Humans; Hydroxyind

1991
Temporal studies of the inhibition of voluntary ethanol intake in the rat induced by intermittent ethanol treatment and some long term neurochemical consequences.
    Drug and alcohol dependence, 1991, Volume: 28, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Brain; Brain Mapping; Dopamin

1991
Cerebrospinal fluid variables among alcoholics lack seasonal variation.
    Acta psychiatrica Scandinavica, 1991, Volume: 84, Issue:6

    Topics: Adult; Alcoholism; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxy

1991
Genetic sensitivity to effect of ethanol on dopaminergic system in alcohol preferring rats.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Brain; Caudate Nucleus; Dopamine; Ethanol; Fron

1991
Depression among alcoholics. Relationship to clinical and cerebrospinal fluid variables.
    Archives of general psychiatry, 1991, Volume: 48, Issue:5

    Topics: Adult; Age Factors; Alcohol Drinking; Alcoholism; Anxiety Disorders; Depressive Disorder; Divorce; D

1991
Dementias, psychological tests, and neurotransmitters.
    Archives of gerontology and geriatrics, 1985, Volume: 4, Issue:4

    Topics: Aged; Alcoholism; Alzheimer Disease; Dementia; Diagnosis, Differential; Female; Homovanillic Acid; H

1985
Contents of monoamines in forebrain regions of alcohol-preferring (P) and -nonpreferring (NP) lines of rats.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Biogenic Amines; Brain; Cereb

1987
Relationship of psychobiological variables to recidivism in violent offenders and impulsive fire setters. A follow-up study.
    Archives of general psychiatry, 1989, Volume: 46, Issue:7

    Topics: Adult; Alcoholism; Blood Glucose; Criminal Psychology; Depressive Disorder; Disruptive, Impulse Cont

1989
Homicide, suicide and CSF 5-HIAA.
    Acta psychiatrica Scandinavica, 1985, Volume: 71, Issue:3

    Topics: Adult; Aggression; Alcoholism; Homicide; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

1985
High correlations of norepinephrine, dopamine, and epinephrine and their major metabolite excretion rates.
    Archives of general psychiatry, 1988, Volume: 45, Issue:8

    Topics: Adult; Alcoholism; Circadian Rhythm; Depressive Disorder; Dopamine; Epinephrine; Female; Homovanilli

1988
[Catecholamine content of the rat brain at different stages of experimental alcoholism].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 99, Issue:3

    Topics: Alcoholism; Animals; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Hypothalamus; Male

1985
CSF monoamine metabolites in alcoholism: a comparative study with depression.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:4

    Topics: Adult; Aged; Alcoholism; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Ma

1974
Amphetamine psychosis: behavioral and biochemical aspects.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Adolescent; Adult; Affect; Alcoholism; Amphetamine; Brain; Cognition Disorders; Delusions; Depressio

1974
Homovanillic acid in cerebrospinal fluid of alcoholics.
    The New England journal of medicine, 1973, Jun-21, Volume: 288, Issue:25

    Topics: Adolescent; Adult; Aged; Alcoholism; Homovanillic Acid; Humans; Middle Aged; Phenylacetates; Wernick

1973