Page last updated: 2024-10-21

homovanillic acid and Aging

homovanillic acid has been researched along with Aging in 122 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Using percutaneously placed arterial and venous catheters, we examined the influence of aging on the plasma concentration, whole body production rate, and renal clearance of homovanillic acid (HVA) in 60 healthy adult volunteers."7.69The influence of aging on the plasma concentration and renal clearance of homovanillic acid. ( Eisenhofer, G; Esler, MD; Lambert, GW, 1994)
"The aging of the cochlear dopaminergic system has been analyzed by quantifying the levels of dopamine (DA) and its metabolites (3,4-dihydroxyphenylacetic acid, DOPAC, and homovanillic acid, HVA) in adult rats aged 3, 12 or 24 months."3.71Effects of aging on cochlear monoamine turnover. ( Dávila, D; Gil-Loyzaga, P; Muñoz, E; Vicente-Torres, MA, 2002)
" In addition, the exposure to new environmental condition elevated blood corticosterone levels and enhanced behavioral activities to a greater extent in the Dex group than in controls at 7 wk of life, suggesting that elevated glucocorticoid levels during the pregnancy mimicked prenatal mild stress, producing developmental alterations in brain monoamine metabolism, endocrine response, and behavior in adult offspring."3.69Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring. ( Kamei, K; Kitera, K; Mikuni, M; Muneoka, K; Ogawa, T; Takahashi, K; Takigawa, M, 1997)
"To examine the possible causal contribution of normal or accelerated aging to the neurodegenerative process of Parkinson's disease, we measured the influence of aging on subregional striatal dopamine and homovanillic acid levels in postmortem brain of 23 neurologically and psychiatrically normal human subjects 14-92 years old."3.68Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease. ( Deck, JH; Hornykiewicz, O; Kish, SJ; Rajput, A; Shannak, K, 1992)
" The results indicate that aging did not significantly alter the levels of norepinephrine (NE), dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in frontal (FCX), parietal (PCX) and occipital cortices (OCX)."3.68Effect of aging and diet restriction on monoamines and amino acids in cerebral cortex of Fischer-344 rats. ( Friedman, E; Yeung, JM, 1991)
"The long-term effect of the parkinsonism-inducing neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central monoaminergic neurons in young (2-3 months) and aging (12 months) C57BL/6 mice has been studied using neurochemical and immunocytochemical techniques."3.68Long-term effect of MPTP in the mouse brain in relation to aging: neurochemical and immunocytochemical analysis. ( Date, I; Felten, DL; Felten, SY, 1990)
"Measurements of dopamine (DA) and its metabolites in plasma (DA sulfate) and urine (homovanillic acid) as well as its urinary response to furosemide revealed two distinct patterns: a hyperdopaminergic state in borderline essential hypertension (EH) and a renal DA deficiency in stable EH."3.68Peripheral dopamine in essential hypertension. An early defense against hypertension failing during its progression? ( Kuchel, O, 1990)
" Neither cortical NE nor its metabolite methoxyhydroxyphenylglycol sulphate (MHPG-SO4) were significantly changed by aging."3.67Effect of aging on monoamines and their metabolites in the rat brain. ( Carfagna, N; Moretti, A; Trunzo, F, 1987)
"Noradrenaline, dopamine, homovanillic acid (HVA), choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) levels were measured in post-mortem brains from 8 cases of pre-senile Alzheimer-type dementia (ATD), 5 cases of senile ATD, 4 cases of Down's syndrome aged 53-57 years, one 27-year-old case of Down's syndrome and 13 controls."3.66Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome. ( Allison, Y; Gordon, A; Maloney, AF; Ritchie, IM; Simpson, J; Urquhart, A; Yates, CM, 1983)
"Withaferin A (WA) was evaluated for its neuro-protective efficacy on ageing induced striatal dopamine (DA) and behavioural changes in aged rats."1.51Ameliorative Effect of Withaferin A on Ageing-Mediated Impairment in the Dopamine System and Its Associated Behavior of Wistar Albino Rat. ( Ibrahim, M; Prabhu, K; Rajasankar, S; Raziya Banu, M, 2019)
"Levodopa (l-DOPA, l-3,4-dihydroxyphenylalanine) is the most effective drug in the symptomatic treatment of Parkinson's disease (PD), but chronic use initiates a maladaptive process leading to l-DOPA-induced dyskinesia (LID)."1.46Cerebrospinal fluid levels of catecholamines and its metabolites in Parkinson's disease: effect of l-DOPA treatment and changes in levodopa-induced dyskinesia. ( Andersen, AD; Binzer, M; Blaabjerg, M; Gramsbergen, JBP; Kamal, A; Kjaer, TW; Stenager, E; Thagesen, H, 2017)
"Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder of mature and older individuals."1.36Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration. ( Charlton, CG; King, J; Mackey, V; Muthian, G, 2010)
"Idiopathic Parkinson's disease (PD) is associated with advanced age, but it is still unclear whether dopaminergic neuronal death results from events initiated during development, adulthood, or represents a cumulative effect across the span of life."1.31Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype. ( Baggs, RB; Cory-Slechta, DA; Goodman, BM; Richfield, EK; Thiruchelvam, M, 2002)
" Although increasing the dosage of d-METH (20 to 80 mg/kg) did increase the GFAP response (100% over control), it was still well below that usually exhibited at the usual neurotoxic dosage (300-400% over control) in fully mature mice."1.31Age as a susceptibility factor in the striatal dopaminergic neurotoxicity observed in the mouse following substituted amphetamine exposure. ( Ali, SF; Miller, DB; O'Callaghan, JP, 2000)
" A treatment history of high AMPH dosage was associated with a marked sensitization of the exploratory behavior in adults, whereas it induced a quite opposite profile in periadolescents."1.31Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats. ( Laviola, G; Pascucci, T; Pieretti, S, 2001)
"The Fragile X syndrome, a common form of mental retardation in humans, is caused by silencing the fragile X mental retardation (FMR1) gene leading to the absence of the encoded fragile X mental retardation protein 1 (FMRP)."1.31Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome. ( Braun, K; Gruss, M, 2001)
"Sodium azide is an inhibitor of cytochrome oxidase which produces selective striatal lesions in both rodents and primates."1.29Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism. ( Beal, MF; Brouillet, E; Henshaw, DR; Hyman, BT; Jenkins, BG; Rosen, BR; Schulz, JB; Sodhi, P, 1994)
" These results suggest that SAM rapidly undergoes neurochemical changes which are considered to be part of the normal aging process, and these changes were attenuated by chronic administration of nimodipine."1.29Neurochemical changes related to ageing in the senescence-accelerated mouse brain and the effect of chronic administration of nimodipine. ( Kabuto, H; Mori, A; Murakami, M; Sawada, S; Yokoi, I, 1995)
" Eighteen-day-old rats were 35% and 63% more sensitive than adults to the effects of haloperidol on striatal and accumbens turnover and had steeper dose-response curves."1.29Developmental differences in acute nigrostriatal and mesocorticolimbic system response to haloperidol. ( Baldessarini, RJ; Barber, NI; Campbell, A; Gallitano, AL; Gelbard, HA; Marsh, E; Teicher, MH, 1993)
" A dose-response effect of apomorphine on extracellular dopamine was observed in all age groups except at 10-11 days of age."1.29The ontogeny of apomorphine-induced alterations of neostriatal dopamine release: effects on spontaneous release. ( Andersen, SL; Gazzara, RA, 1993)
"The effects of neonatal hydrocephalus on the levels of tyrosine, tryptophan, 5-hydroxyindoleacetic acid (5-HIAA), and homovanillic acid (HVA) in CSF were determined by high-performance liquid chromatography (HPLC) with fluorometric detection in normal and chronically hydrocephalic rabbits."1.29Neuroamine related compounds in the CSF of hydrocephalic rabbits. ( Faull, KF; Fisher, RS; Fluharty, AL; Gayek, RJ; Lazareff, JA; Olmstead, CE; Orlino, EN; Peacock, WJ; Wehby-Grant, MC, 1995)
"There is some evidence that Parkinson's disease (PD) seems to be a heterogenous and generalized brain disorder reflecting a degeneration of multiple neuronal networks, including somatostatinergic neurons."1.29Somatostatin-like immunoreactivity, its molecular forms and monoaminergic metabolites in aged and demented patients with Parkinson's disease--effect of L-Dopa. ( Cramer, H; Hamann, GF; Schimrigk, K; Strittmatter, M; Strubel, D, 1996)
" Part 1 of the study established a dose-response curve and the temporal pattern of GSH loss and recovery in the substantia nigra and striatum following acute BSO treatment."1.29Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons. ( Andersen, JK; Hamill, RW; Harnish, P; Hom, DG; Lee, FY; McNeill, TH; Mo, JQ, 1996)
"Biogenic amines in pons and striatum have been dosed in twenty-four months old Wistar male rats."1.27[Biochemical changes in 24-month-old Wistar rats]. ( Della Zuana, O; Duhault, J; Lonchampt, M; Roman, F; Saint Romas, G, 1984)

Research

Studies (122)

TimeframeStudies, this research(%)All Research%
pre-199034 (27.87)18.7374
1990's51 (41.80)18.2507
2000's27 (22.13)29.6817
2010's10 (8.20)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raziya Banu, M1
Ibrahim, M1
Prabhu, K1
Rajasankar, S1
Pierno, S1
Tricarico, D1
Liantonio, A1
Mele, A1
Digennaro, C1
Rolland, JF1
Bianco, G1
Villanova, L1
Merendino, A1
Camerino, GM1
De Luca, A1
Desaphy, JF1
Camerino, DC1
Li, Y1
Sun, Y1
Yang, J1
Wu, Y1
Yu, J1
Li, B1
Andersen, AD1
Blaabjerg, M1
Binzer, M1
Kamal, A1
Thagesen, H1
Kjaer, TW1
Stenager, E1
Gramsbergen, JBP1
Niimi, K1
Takahashi, E1
Itakura, C1
Ling, Z1
Zhu, Y1
Tong, CW1
Snyder, JA1
Lipton, JW2
Carvey, PM2
Hunter, RL1
Liu, M1
Choi, DY1
Cass, WA1
Bing, G1
Heermann, S1
Opazo, F1
Falkenburger, B1
Krieglstein, K1
Spittau, B1
Muthian, G1
Mackey, V1
King, J1
Charlton, CG1
Oyama, G1
Yoshimi, K1
Natori, S1
Chikaoka, Y1
Ren, YR1
Funayama, M1
Shimo, Y1
Takahashi, R1
Nakazato, T1
Kitazawa, S1
Hattori, N1
Allen, E1
Carlson, KM1
Zigmond, MJ1
Cavanaugh, JE1
Schumm, S1
Sebban, C1
Cohen-Salmon, C1
Callebert, J1
Launay, JM1
Golmard, JL1
Boussicault, L1
Petropoulos, I1
Hild, A1
Rousselet, E1
Prigent, A1
Friguet, B1
Mariani, J1
Hirsch, EC1
Baiguera, C1
Alghisi, M1
Pinna, A1
Bellucci, A1
De Luca, MA1
Frau, L1
Morelli, M1
Ingrassia, R1
Benarese, M1
Porrini, V1
Pellitteri, M1
Bertini, G1
Fabene, PF1
Sigala, S1
Spillantini, MG1
Liou, HC1
Spano, PF1
Pizzi, M1
Miura, H1
Qiao, H1
Ohta, T1
Thiruchelvam, M1
Richfield, EK1
Goodman, BM1
Baggs, RB1
Cory-Slechta, DA1
Stanford, JA1
Vorontsova, E1
Surgener, SP1
Gerhardt, GA2
Fowler, SC1
Haycock, JW1
Becker, L1
Ang, L1
Furukawa, Y1
Hornykiewicz, O2
Kish, SJ2
Rapoport, SI1
Schapiro, MB1
May, C1
Segovia, G1
Mora, F1
Götz, ME1
Malz, CR1
Dirr, A1
Blum, D1
Gsell, W1
Schmidt, S1
Burger, R1
Pohli, S1
Riederer, P1
Martí, MB1
Cano, AH1
Villareal, EM1
Martínez, SG1
Bernet, IM1
Chanut, E1
Labarthe, B1
Lacroix, B1
Noda, A1
Gasdeblay, S1
Bondier, JR1
Versaux-Botteri, C1
Arborelius, L1
Eklund, MB1
Roman, F1
Della Zuana, O1
Lonchampt, M1
Saint Romas, G1
Duhault, J1
Simpkins, JW1
Lasley, SM1
Greenland, RD1
Minnema, DJ1
Michaelson, IA1
Muramoto, O1
Ando, K1
Carlsson, A1
Adolfsson, R2
Aquilonius, SM1
Gottfries, CG3
Oreland, L1
Svennerholm, L1
Winblad, B2
Seifert, WE1
Foxx, JL1
Butler, IJ1
Ponzio, F3
Calderini, G2
Lomuscio, G2
Vantini, G3
Toffano, G2
Algeri, S3
Bareggi, SR1
Franceschi, M1
Bonini, L1
Zecca, L1
Smirne, S1
Yoshino, K1
Silverstein, FS1
Donn, S1
Buchanan, K1
Johnston, MV1
Yates, CM1
Simpson, J1
Gordon, A1
Maloney, AF1
Allison, Y1
Ritchie, IM1
Urquhart, A1
Nakamura, S3
Yamao, S1
Iijima, S1
Kaji, R1
Kameyama, M1
Miyata, S2
Itoh, J1
Mimori, Y1
Achilli, G1
Cimino, M1
Perego, C1
Venero, JL3
Machado, A7
Cano, J7
Brouillet, E1
Hyman, BT1
Jenkins, BG1
Henshaw, DR1
Schulz, JB1
Sodhi, P1
Rosen, BR1
Beal, MF1
Irwin, I1
DeLanney, LE1
McNeill, T1
Chan, P1
Forno, LS1
Murphy, GM1
Di Monte, DA1
Sandy, MS1
Langston, JW1
Gupta, M1
Wiener, HL1
Kabuto, H1
Yokoi, I1
Mori, A1
Murakami, M1
Sawada, S1
Cole, M1
Craft, AW1
Parker, L1
Bell, S1
Seviour, JA1
McGill, AC1
Dale, G1
Erdtsieck-Ernste, EB1
Feenstra, MG1
Botterblom, M1
Boer, GJ1
Santiago, M4
Martinez, M1
Arnalich, F1
Vazquez, JJ1
Hernanz, A1
Dorce, VA1
Palermo-Neto, J1
Ali, SF5
David, SN1
Newport, GD1
Cadet, JL1
Slikker, W1
Tani, Y1
Fernell, E1
Watanabe, Y1
Kanai, T1
Långström, B1
Tsai, YF1
Tsai, HW1
Tai, MY1
Budygin, EA1
Kovalev, GI1
Gaĭntdinov, RR1
Kudrin, VS2
Voronina, TA1
Tsuchida, K1
Ujike, H1
Kanzaki, A1
Fujiwara, Y1
Akiyama, K1
Joseph, SA1
Walker, DW1
Teicher, MH1
Barber, NI1
Gelbard, HA1
Gallitano, AL1
Campbell, A1
Marsh, E1
Baldessarini, RJ1
Andersen, SL1
Gazzara, RA1
Rose, S2
Nomoto, M1
Jackson, EA1
Gibb, WR1
Jaehnig, P1
Jenner, P2
Marsden, CD2
Cabib, S1
Puglisi-Allegra, S1
D'Amato, FR1
Olmstead, CE1
Lazareff, JA1
Orlino, EN1
Fluharty, AL1
Faull, KF2
Peacock, WJ1
Wehby-Grant, MC1
Gayek, RJ1
Fisher, RS1
Hastings, JA2
Pavia, JM2
Morris, MJ2
Strittmatter, M1
Hamann, GF1
Strubel, D1
Cramer, H1
Schimrigk, K1
Andersen, JK1
Mo, JQ1
Hom, DG1
Lee, FY1
Harnish, P1
Hamill, RW1
McNeill, TH1
Ueda, Y1
Komatsu, M1
Hiramatsu, M1
Lambert, GW1
Eisenhofer, G1
Esler, MD1
Muneoka, K1
Mikuni, M1
Ogawa, T1
Kitera, K1
Kamei, K1
Takigawa, M1
Takahashi, K1
Philpot, RM2
Kirstein, CL2
Schneider, ML1
Clarke, AS1
Kraemer, GW2
Roughton, EC1
Lubach, GR1
Rimm-Kaufman, S1
Schmidt, D1
Ebert, M1
Maloney, RE1
Pick, LH1
Halperin, JM1
Schwartz, ST1
Newcorn, JH1
Kucherianu, VG1
Kryzhanovskiĭ, GN1
Iurasov, VV1
Nikushkin, EV1
Zhigal'tsev, IV1
Ling, ZD1
Collier, TJ1
Sortwell, CE1
Vu, TQ1
Robie, HC1
Shui, H1
Peng, Y1
Wu, R1
Tsai, Y1
Miller, DB1
O'Callaghan, JP1
Mandavilli, BS1
Van Houten, B1
Lee, JJ1
Chang, CK1
Liu, IM1
Chi, TC1
Yu, HJ1
Cheng, JT1
Laviola, G1
Pascucci, T1
Pieretti, S1
Takeuchi, Y1
Matsushita, H1
Sakai, H1
Kawano, H1
Ochi, M1
Goettl, VM1
Wemlinger, TA1
Colvin, AE1
Neff, NH1
Hadjiconstantinou, M1
Ferreira, A1
Bettencourt, P1
Pestana, M1
Correia, F1
Serrão, P1
Martins, L1
Cerqueira-Gomes, M1
Soares-Da-Silva, P1
Imam, SZ1
Vicente-Torres, MA2
Muñoz, E2
Dávila, D2
Gil-Loyzaga, P2
Gruss, M1
Braun, K1
Meyer, JS1
Muskiet, FA1
Fremouw-Ottevangers, DC1
van der Meulen, J1
Wolthers, BG1
de Vries, JA1
Roos, BE1
Davis, AJ1
Holzbauer, M1
Sharman, DF1
Raleigh, MJ1
Brammer, GL1
McGuire, MT1
Pollack, DB1
Yuwiler, A1
Howells, DW1
Hyland, K1
Smith, I1
Strobel, S1
Pasinetti, GM1
Osterburg, HH1
Kelly, AB1
Kohama, S1
Morgan, DG1
Reinhard, JF1
Stellwagen, RH1
Finch, CE1
Arai, H1
Ichimiya, Y1
Kosaka, K1
Moroji, T1
Iizuka, R1
Martineau, J1
Garreau, B1
Barthélémy, C1
Jouve, J1
Lelord, G1
Higley, JD1
Suomi, SJ1
Linnoila, M1
Takahashi, S1
Abe, T1
Taylor, MD1
de Ceballos, ML1
Chong, PN1
Davis, BA1
Durden, DA1
O'Reilly, RL1
Shannak, K1
Rajput, A1
Deck, JH1
Yeung, JM1
Friedman, E1
Date, I1
Felten, DL1
Felten, SY1
Godefroy, F1
Bassant, MH1
Lamour, Y1
Weil-Fugazza, J1
Kuchel, O1
Walters, DE1
Chapman, CD1
Howard, SG1
Hedner, J1
Lundell, KH1
Breese, GR1
Mueller, RA1
Hedner, T1
Sunderland, T1
Tariot, PN1
Cohen, RM1
Newhouse, PA1
Mellow, AM1
Mueller, EA1
Murphy, DL1
Moretti, A2
Carfagna, N2
Trunzo, F2
Reinoso-Suárez, F1
Vaughn, DM1
Smyth, GB1
Whitmer, WL1
Satjawatcharaphong, C1
Ebert, MH1
Schmidt, DE1
McKinney, WT1
Stahl, SM1
Thiemann, S1
Barchas, JD1
Berger, PA1
MacRae, PG1
Spirduso, WW1
Walters, TJ1
Farrar, RP1
Wilcox, RE1
Kumami, K1
Mrsulja, BB1
Ueki, Y1
Djuricić, BD1
Spatz, M1
Hunneman, DH1
Jonas, W1
Gabriel, M1
Gahr, M1
Cousin, KM1
Gerald, MC1
Uretsky, NJ1

Reviews

2 reviews available for homovanillic acid and Aging

ArticleYear
[Biogenic amines and aging (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1981, Volume: 26, Issue:11

    Topics: Adult; Aged; Aging; Alzheimer Disease; Biogenic Amines; Brain; Catecholamines; Homovanillic Acid; Hu

1981
Human brain levels of monoamines and their metabolites. Postmortem investigations.
    Acta psychiatrica Scandinavica. Supplementum, 1980, Volume: 280

    Topics: Adolescent; Adult; Affective Symptoms; Aging; Autopsy; Brain Chemistry; Catecholamines; Child; Dopam

1980

Other Studies

120 other studies available for homovanillic acid and Aging

ArticleYear
Ameliorative Effect of Withaferin A on Ageing-Mediated Impairment in the Dopamine System and Its Associated Behavior of Wistar Albino Rat.
    Pharmacology, 2019, Volume: 103, Issue:3-4

    Topics: Age Factors; Aging; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dopaminergic Neurons; Homo

2019
An olive oil-derived antioxidant mixture ameliorates the age-related decline of skeletal muscle function.
    Age (Dordrecht, Netherlands), 2014, Volume: 36, Issue:1

    Topics: Administration, Oral; Aging; Animals; Antioxidants; Brain; Calcium; Chloride Channels; Gallic Acid;

2014
Age-dependent dopaminergic dysfunction following fetal exposure to atrazine in SD rats.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Atrazine; Corpus Striatum; Dopamine; Dopamine Plasma

2014
Cerebrospinal fluid levels of catecholamines and its metabolites in Parkinson's disease: effect of l-DOPA treatment and changes in levodopa-induced dyskinesia.
    Journal of neurochemistry, 2017, Volume: 141, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aging; Antiparkinson Agents; Catecholamines; Dopamine;

2017
Analysis of motor function and dopamine systems of SAMP6 mouse.
    Physiology & behavior, 2009, Mar-02, Volume: 96, Issue:3

    Topics: Aging; Analysis of Variance; Animals; Brain; Cerebellum; Dopamine; Homovanillic Acid; Male; Mice; Mi

2009
Prenatal lipopolysaccharide does not accelerate progressive dopamine neuron loss in the rat as a result of normal aging.
    Experimental neurology, 2009, Volume: 216, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Analysis of Variance; Animals; Body Weight; Brai

2009
Inflammation and age-related iron accumulation in F344 rats.
    Current aging science, 2008, Volume: 1, Issue:2

    Topics: Age Factors; Aging; Animals; Dopamine; Endotoxins; Ferritins; Homovanillic Acid; Inflammation; Iron;

2008
Aged Tgfbeta2/Gdnf double-heterozygous mice show no morphological and functional alterations in the nigrostriatal system.
    Journal of neural transmission (Vienna, Austria : 1996), 2010, Volume: 117, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Chromatography, High Pressure

2010
Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration.
    Neuroscience, 2010, Sep-01, Volume: 169, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Birth

2010
Impaired in vivo dopamine release in parkin knockout mice.
    Brain research, 2010, Sep-17, Volume: 1352

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Body Weight; Corpus Striatum; Dopamine; Homovanillic

2010
L-DOPA reverses motor deficits associated with normal aging in mice.
    Neuroscience letters, 2011, Feb-01, Volume: 489, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Dopamine; Dopamine Agents; H

2011
Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Journal of neurochemistry, 2012, Volume: 122, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; An

2012
Late-onset Parkinsonism in NFκB/c-Rel-deficient mice.
    Brain : a journal of neurology, 2012, Volume: 135, Issue:Pt 9

    Topics: Aging; alpha-Synuclein; Animals; Cell Count; Corpus Striatum; Dopamine; Dopaminergic Neurons; Homova

2012
Influence of aging and social isolation on changes in brain monoamine turnover and biosynthesis of rats elicited by novelty stress.
    Synapse (New York, N.Y.), 2002, Volume: 46, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Brain; Chromatography, High Pre

2002
Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype.
    Neurotoxicology, 2002, Volume: 23, Issue:4-5

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Cell Count; Chromatography, High Pressure Liquid; Dop

2002
Aged Fischer 344 rats exhibit altered locomotion in the absence of decreased locomotor activity: exacerbation by nomifensine.
    Neuroscience letters, 2002, Nov-29, Volume: 333, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Analysis of Variance; Animals; Corpus Striatum;

2002
Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum.
    Journal of neurochemistry, 2003, Volume: 87, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Aromatic-L-Amino-Acid Decarboxylases

2003
Reduced brain delivery of homovanillic acid to cerebrospinal fluid during human aging.
    Archives of neurology, 2004, Volume: 61, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Aging; Blood-Brain Barrier; Brain Chemistry; Female; Homovanillic Ac

2004
Dopamine and GABA increases produced by activation of glutamate receptors in the nucleus accumbens are decreased during aging.
    Neurobiology of aging, 2005, Volume: 26, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ana

2005
Brain aging phenomena in migrating sockeye salmon Oncorhynchus nerka nerka.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animal Migration; Animals; Antioxidants; Apoptosis; Brain; Ca

2005
Brain delivery of homovanillic acid to cerebrospinal fluid during human aging.
    Archives of neurology, 2005, Volume: 62, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Artifacts; Brain; Cerebrospinal Fluid; Dopamine; Down-Regulat

2005
Variations of dopamine, serotonin, and amino acid concentrations in Noda epileptic rat (NER) retina.
    Brain research, 2006, Jan-27, Volume: 1070, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acids; Animals; Animals, Newborn; Biogenic Monoamines;

2006
Both long and brief maternal separation produces persistent changes in tissue levels of brain monoamines in middle-aged female rats.
    Neuroscience, 2007, Mar-16, Volume: 145, Issue:2

    Topics: Aging; Animals; Biogenic Monoamines; Brain; Depressive Disorder; Dopamine; Down-Regulation; Female;

2007
[Biochemical changes in 24-month-old Wistar rats].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1984, Volume: 178, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholinesterase; Aging; Animals; Choline; Choline O-Acetyltrans

1984
Regional changes in monoamine metabolism in the aging constant estrous rat.
    Neurobiology of aging, 1984,Winter, Volume: 5, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Corpus Striatum; Dopamine; Estrus; Female; Ho

1984
Influence of chronic inorganic lead exposure on regional dopamine and 5-hydroxytryptamine turnover in rat brain.
    Neurochemical research, 1984, Volume: 9, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Dopamine; Erythrocytes; Female; Homovanillic

1984
Biogenic amines in human brain in normal aging, senile dementia, and chronic alcoholism.
    Advances in biochemical psychopharmacology, 1980, Volume: 23

    Topics: 5-Methoxytryptamine; Adult; Aged; Aging; Alcoholism; Brain; Dementia; Dopamine; Homovanillic Acid; H

1980
Age effect on dopamine and serotonin metabolite levels in cerebrospinal fluid.
    Annals of neurology, 1980, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Glycols; Homovanillic Acid; Humans; Hydroxyindole

1980
Changes in monoamines and their metabolite levels in some brain regions of aged rats.
    Neurobiology of aging, 1982,Spring, Volume: 3, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleace

1982
Decreased CSF concentrations of homovanillic acid and gamma-aminobutyric acid in Alzheimer's disease. Age- or disease-related modifications?
    Archives of neurology, 1982, Volume: 39, Issue:11

    Topics: Age Factors; Aged; Aging; Alzheimer Disease; Brain Chemistry; Dementia; Female; gamma-Aminobutyric A

1982
[Concentrations of monoamines and monoamine metabolites in cerebrospinal fluid determined by high-performance liquid chromatography with electrochemical detection].
    No to shinkei = Brain and nerve, 1982, Volume: 34, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Aged; Aging; Biogenic Amines; Chromatography, Hig

1982
Changes with age in rat central monoaminergic system responses to cold stress.
    Neurobiology of aging, 1982,Fall, Volume: 3, Issue:3

    Topics: Aging; Animals; Body Temperature Regulation; Brain; Brain Stem; Cold Temperature; Corticosterone; Do

1982
Concentrations of homovanillic acid and 5-hydroxyindoleacetic acid in cerebrospinal fluid from human infants in the perinatal period.
    Journal of neurochemistry, 1984, Volume: 43, Issue:6

    Topics: Aging; Female; Gestational Age; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant,

1984
Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome.
    Brain research, 1983, Nov-28, Volume: 280, Issue:1

    Topics: Acetylcholinesterase; Adult; Aged; Aging; Alzheimer Disease; Brain; Choline O-Acetyltransferase; Dem

1983
[Age-related changes in nervous system].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1984, Volume: 21, Issue:3

    Topics: Adult; Aged; Aging; Cerebrospinal Fluid; Electroencephalography; Evoked Potentials, Somatosensory; G

1984
Study on some compensatory responses of dopaminergic system in aging rats.
    Experimental brain research, 1982, Volume: Suppl 5

    Topics: Aging; Animals; Apomorphine; Butyrophenones; Corpus Striatum; Feedback; Haloperidol; Homovanillic Ac

1982
Effect of ageing on monoamine turnover in the prefrontal cortex of rats.
    Mechanisms of ageing and development, 1993, Dec-15, Volume: 72, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hy

1993
Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism.
    Experimental neurology, 1994, Volume: 129, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Triphosphate; Aging; Animals; Azides; Biogenic Amines; Cor

1994
Aging and the nigrostriatal dopamine system: a non-human primate study.
    Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration, 1994, Volume: 3, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analys

1994
Effects of deprenyl on monoamine oxidase and neurotransmitters in the brains of MPTP-treated aging mice.
    Neurochemical research, 1995, Volume: 20, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain;

1995
Neurochemical changes related to ageing in the senescence-accelerated mouse brain and the effect of chronic administration of nimodipine.
    Mechanisms of ageing and development, 1995, Apr-21, Volume: 80, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Administration, Oral; Aging; Animals; Brain; Calcium

1995
Urinary creatinine adjusted reference ranges for homovanillic and vanillylmandelic acid in children and adults.
    Clinica chimica acta; international journal of clinical chemistry, 1995, Apr-30, Volume: 236, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Body Height; Body Weight; Child; Child, Preschool

1995
Postnatal exposure to the beta-adrenoceptor agonist clenbuterol has regionally selective direct and long-term effects on rat brain beta-adrenoceptors and monoamine metabolism.
    Brain research. Developmental brain research, 1993, Jan-15, Volume: 71, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Brain; Cerebellum; Clenbuterol; Do

1993
Effects of age and dopamine agonists and antagonists on striatal dopamine release in the rat: an in vivo microdialysis study.
    Mechanisms of ageing and development, 1993, Volume: 67, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dialys

1993
Altered cerebrospinal fluid amino acid pattern in the anorexia of aging: relationship with biogenic amine metabolism.
    Life sciences, 1993, Volume: 53, Issue:21

    Topics: Aged; Aged, 80 and over; Aging; Amino Acids; Anorexia; Biogenic Amines; Body Weight; Female; Homovan

1993
Behavioral and neurochemical changes induced by aging in dopaminergic systems of male and female rats.
    Physiology & behavior, 1994, Volume: 56, Issue:5

    Topics: Aging; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Female; Homovanillic Acid;

1994
MPTP-induced oxidative stress and neurotoxicity are age-dependent: evidence from measures of reactive oxygen species and striatal dopamine levels.
    Synapse (New York, N.Y.), 1994, Volume: 18, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbre

1994
Decrease in 6R-5,6,7,8-tetrahydrobiopterin content in cerebrospinal fluid of autistic patients.
    Neuroscience letters, 1994, Nov-07, Volume: 181, Issue:1-2

    Topics: Adolescent; Adult; Aging; Autistic Disorder; Biopterins; Child; Child, Preschool; Female; Homovanill

1994
Comparison of brain dopamine depletion induced by low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in young and aged rats.
    Neuroscience research, 1994, Volume: 20, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain;

1994
[Age-related changes in the dopaminergic system in rat striatum].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 115, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Basal Metabolism; Corpus Striatum; Dopamine; Homovan

1993
Ontogeny of enhanced striatal dopamine release in rats with methamphetamine-induced behavioral sensitization.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Brain Chemistry; Chromatography, H

1994
Monoamine concentrations in cerebrospinal fluid of fetal and newborn sheep.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Biogenic Monoamines; Dinoprostone;

1994
Developmental differences in acute nigrostriatal and mesocorticolimbic system response to haloperidol.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 9, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Dose-Response Relationshi

1993
The ontogeny of apomorphine-induced alterations of neostriatal dopamine release: effects on spontaneous release.
    Journal of neurochemistry, 1993, Volume: 61, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Apomorphine; Corpus Striatum; Dopamine; Dose-Respons

1993
Age-related effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of common marmosets.
    European journal of pharmacology, 1993, Jan-12, Volume: 230, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Callithrix; Chromatography,

1993
Effects of postnatal stress on dopamine mesolimbic system responses to aversive experiences in adult life.
    Brain research, 1993, Feb-26, Volume: 604, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Apomorphine; Dopamine; Female;

1993
Neuroamine related compounds in the CSF of hydrocephalic rabbits.
    Neuroreport, 1995, Sep-11, Volume: 6, Issue:13

    Topics: Aging; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Homovanillic Acid; Hydro

1995
Altered in vivo catecholamine release in the hypothalamic paraventricular nucleus of the aged rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Catecholamines; Homovanillic Acid; Male; Norepinephr

1996
Somatostatin-like immunoreactivity, its molecular forms and monoaminergic metabolites in aged and demented patients with Parkinson's disease--effect of L-Dopa.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Biogenic Monoamines; Dementia; Female; Homovanillic Acid; Humans; Hy

1996
Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antioxidants; Buthionine Sulfoximine; Corpus Striatu

1996
Free radical scavenging activity of the Japanese herbal medicine toki-shakuyaku-san (TJ-23) and its effect on superoxide dismutase activity, lipid peroxides, glutamate, and monoamine metabolites in aged rat brain.
    Neurochemical research, 1996, Volume: 21, Issue:8

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acids; Animals; Bepridil; Biogenic Monoamines; Biphenyl

1996
Neuropeptide Y and [Leu31,Pro34]neuropeptide Y potentiate potassium-induced noradrenaline release in the paraventricular nucleus of the aged rat.
    Brain research, 1997, Mar-07, Volume: 750, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Cerebral Ventricles; Drug Synergism; Homovanillic Ac

1997
The influence of aging on the plasma concentration and renal clearance of homovanillic acid.
    Psychoneuroendocrinology, 1994, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Female; Glomerular Filtration Rate; Homovanillic Acid; Humans; Male;

1994
Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex; Aging; Analysis of Variance; Animals; Biogenic Monoa

1997
The effects of repeated alcohol exposure on the neurochemistry of the periadolescent nucleus accumbens septi.
    Neuroreport, 1998, May-11, Volume: 9, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alcoholism; Animals; Dopamine; Dose-Response Relationship, Dr

1998
Prenatal stress alters brain biogenic amine levels in primates.
    Development and psychopathology, 1998,Summer, Volume: 10, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Biogenic Amines; Brain; Female; Ho

1998
Microdialysis studies of basal levels and stimulus-evoked overflow of dopamine and metabolites in the striatum of young and aged Fischer 344 rats.
    Brain research, 1999, Jan-16, Volume: 816, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Corpus Striatum; Dextroampheta

1999
A longitudinal study of neurobiological mechanisms in boys with attention-deficit hyperactivity disorder: preliminary findings.
    Biological psychiatry, 1999, Feb-01, Volume: 45, Issue:3

    Topics: Aging; Attention Deficit Disorder with Hyperactivity; Blood Platelets; Brain; Catecholamines; Child;

1999
Repeated cocaine exposure: effects on catecholamines in the nucleus accumbens septi of periadolescent animals.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 62, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Catecholamines; Cocaine; Dopamine; Dopamine Uptake I

1999
[Effect of acidic fibroblast growth factor on experimental parkinsonism and levels of dopamine and its metabolites in the striatum of mice of various ages].
    Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Intran

1999
Striatal trophic activity is reduced in the aged rat brain.
    Brain research, 2000, Feb-21, Volume: 856, Issue:1-2

    Topics: Aging; Animals; Brain; Cells, Cultured; Chromatography, High Pressure Liquid; Corpus Striatum; Dopam

2000
Evaluation of L-DOPA biotransformation during repeated L-DOPA infusion into the striatum in freely-moving young and old rats.
    Brain research. Developmental brain research, 2000, May-11, Volume: 121, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antiparkinson Agents; Chromatography, High Pressure

2000
Age as a susceptibility factor in the striatal dopaminergic neurotoxicity observed in the mouse following substituted amphetamine exposure.
    Annals of the New York Academy of Sciences, 2000, Volume: 914

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Area Under Curve; Body Temperature; Central Nervous

2000
DNA damage in brain mitochondria caused by aging and MPTP treatment.
    Brain research, 2000, Dec-01, Volume: 885, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Animals; Brain Chemistry; DNA Damage; DNA, Mitoc

2000
Changes in endogenous monoamines in aged rats.
    Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Catechol O-Methyltransferase; C

2001
Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats.
    Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Caud

2001
Developmental changes in cerebrospinal fluid concentrations of monoamine-related substances in patients with dentatorubral-pallidoluysian atrophy.
    Journal of child neurology, 2001, Volume: 16, Issue:2

    Topics: Adolescent; Age Factors; Aging; Biogenic Monoamines; Case-Control Studies; Child; Child, Preschool;

2001
Motoric behavior in aged rats treated with GM1.
    Brain research, 2001, Jul-06, Volume: 906, Issue:1-2

    Topics: Aging; Animals; Dopamine; G(M1) Ganglioside; Homovanillic Acid; Male; Motor Activity; Movement Disor

2001
Heart failure, aging, and renal synthesis of dopamine.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Age Factors; Aged; Aging; Aldosterone; Cardiac Output, Low; C

2001
Aging increases the susceptiblity to methamphetamine-induced dopaminergic neurotoxicity in rats: correlation with peroxynitrite production and hyperthermia.
    Journal of neurochemistry, 2001, Volume: 78, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain Chemistry; Central Nervous System Stimulants;

2001
Changes in the cochlear dopaminergic system of the aged rat.
    Brain research, 2001, Oct-26, Volume: 917, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Chromatography, High Pressure Liquid; Cochlea; Dopam

2001
Effects of aging on cochlear monoamine turnover.
    Advances in oto-rhino-laryngology, 2002, Volume: 59

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Chromatography, High Pressure L

2002
Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome.
    Neural plasticity, 2001, Volume: 8, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain St

2001
Serotonergic neurotoxicity of MDMA (ecstasy) in the developing rat brain.
    Annals of the New York Academy of Sciences, 2002, Volume: 965

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Apoptosis; Brain; Dopamine; Female; Homovanillic Aci

2002
Determination of some L-3,4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography.
    Clinical chemistry, 1978, Volume: 24, Issue:1

    Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adult; Aging; Child; Child, Presch

1978
Cathecholamines in the human brain and ageing.
    Scandinavian journal of social medicine. Supplementum, 1977, Volume: 14

    Topics: Aged; Aging; Alzheimer Disease; Autopsy; Brain; Dementia; Dopamine; Homovanillic Acid; Humans; Norep

1977
Postnatal development of dopamine deamination in the striatum of the rat.
    British journal of pharmacology, 1975, Volume: 55, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Deamination; Dopamine; Female; Homo

1975
Individual differences in basal cisternal cerebrospinal fluid 5-HIAA and HVA in monkeys. The effects of gender, age, physical characteristics, and matrilineal influences.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1992, Volume: 7, Issue:4

    Topics: Aging; Animals; Body Weight; Chlorocebus aethiops; Diet; Female; Homovanillic Acid; Hydroxyindoleace

1992
Tryptophan and serotonin metabolism in familial erythrophagocytic lymphohistiocytosis.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:6

    Topics: Aging; Amino Acids; Biopterins; Child, Preschool; Etoposide; Histiocytosis, Non-Langerhans-Cell; Hom

1992
Slow changes of tyrosine hydroxylase gene expression in dopaminergic brain neurons after neurotoxin lesioning: a model for neuron aging.
    Brain research. Molecular brain research, 1992, Volume: 13, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acid Sequence; Animals; Biogenic Monoamines; Corpus Str

1992
Neurotransmitter changes in early- and late-onset Alzheimer-type dementia.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain Chemistry; Choline O-Acetyltransferase; Hom

1992
[Development in the metabolism of dopamine and its derivatives. Application to gross development disorders].
    Neurophysiologie clinique = Clinical neurophysiology, 1992, Volume: 22, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Autistic Disorder; Child; Child, Presch

1992
Turnover of dopamine and serotonin and their metabolites in the striatum of aged rats.
    Journal of neurochemistry, 1991, Volume: 56, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydraz

1991
CSF monoamine metabolite concentrations vary according to age, rearing, and sex, and are influenced by the stressor of social separation in rhesus monkeys.
    Psychopharmacology, 1991, Volume: 103, Issue:4

    Topics: Aging; Animals; Biogenic Monoamines; Cisterna Magna; Female; Homovanillic Acid; Hydroxyindoleacetic

1991
[Age changes in concentrations of monoamines and related substances in the cerebrospinal fluid].
    No to shinkei = Brain and nerve, 1991, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Biogenic Monoamines; Child; Chromatography, High Pressure Liquid; Do

1991
Neuropeptide levels in the basal ganglia of aged common marmosets following prolonged treatment with MPTP.
    Journal of neural transmission. Parkinson's disease and dementia section, 1991, Volume: 3, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Basal

1991
The effect of age, sex, weight and height on the plasma concentrations in healthy subjects of the acidic metabolites of some biogenic monoamines involved in psychiatric and neurological disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:4

    Topics: Adult; Aged; Aging; Biogenic Monoamines; Body Height; Body Weight; Female; Homovanillic Acid; Humans

1991
Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease.
    Journal of neurochemistry, 1992, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Analysis of Variance; Corpus Striatum; Dopamine;

1992
Age effects on monoamine turnover of the rat substantia nigra.
    Brain research, 1991, Aug-23, Volume: 557, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxyla

1991
Effect of aging and diet restriction on monoamines and amino acids in cerebral cortex of Fischer-344 rats.
    Growth, development, and aging : GDA, 1991,Winter, Volume: 55, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acids; Animals; Biogenic Monoamines; Cerebral Cortex; C

1991
Long-term effect of MPTP in the mouse brain in relation to aging: neurochemical and immunocytochemical analysis.
    Brain research, 1990, Jun-11, Volume: 519, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain;

1990
Effect of aging on dopamine metabolism in the rat cerebral cortex: a regional analysis.
    Journal of neural transmission. General section, 1991, Volume: 83, Issue:1-2

    Topics: Aging; Animals; Cerebral Cortex; Dopamine; Homovanillic Acid; Male; Norepinephrine; Rats; Rats, Inbr

1991
Peripheral dopamine in essential hypertension. An early defense against hypertension failing during its progression?
    American journal of hypertension, 1990, Volume: 3, Issue:6 Pt 2

    Topics: Aging; Dopamine; Furosemide; Homovanillic Acid; Humans; Hypertension; Longitudinal Studies; Renin

1990
Development of haloperidol-induced dopamine release in the rat striatum using intracerebral dialysis.
    Journal of neurochemistry, 1990, Volume: 54, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dialysis; Dopamine; Female; Haloper

1990
Developmental variations in CSF monoamine metabolites during childhood.
    Biology of the neonate, 1986, Volume: 49, Issue:4

    Topics: Adolescent; Aging; Biogenic Amines; Child; Child, Preschool; Female; Glycols; Homovanillic Acid; Hum

1986
[Neurotransmitters and degenerative diseases in the central nervous system].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1986, Volume: 23, Issue:1

    Topics: Acetylcholinesterase; Aged; Aging; Brain Diseases; Dementia; Dopamine; Homovanillic Acid; Humans; Hy

1986
Dose-dependent effects of deprenyl on CSF monoamine metabolites in patients with Alzheimer's disease.
    Psychopharmacology, 1987, Volume: 91, Issue:3

    Topics: Aging; Alzheimer Disease; Biogenic Amines; Dose-Response Relationship, Drug; Homovanillic Acid; Huma

1987
Effect of aging on monoamines and their metabolites in the rat brain.
    Neurochemical research, 1987, Volume: 12, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Dopamine; Homovanillic Acid;

1987
Changes in biogenic amines in rat hippocampus during development and aging.
    Life sciences, 1988, Volume: 42, Issue:24

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Dopamine; Hippocampus; Homovani

1988
Analysis of equine cisterna magna cerebrospinal fluid for the presence of some monoamine neurotransmitters and transmitter metabolites.
    Veterinary research communications, 1989, Volume: 13, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Cisterna Magna; Female; Homovan

1989
A longitudinal study of the effect of different social rearing conditions on cerebrospinal fluid norepinephrine and biogenic amine metabolites in rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1989, Volume: 2, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Amines; Female; Homovanillic Acid; Hydroxyi

1989
Age-related changes of catecholamines and their metabolites content in the visual system of the rat.
    Mechanisms of ageing and development, 1989, Volume: 47, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Catecholamines; Dopamine; Geniculate Bodies; Homovan

1989
[Ageing and neurotransmitters].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1985, Volume: 74, Issue:10

    Topics: Acetylcholine; Aged; Aging; Alzheimer Disease; Animals; Brain; Choline O-Acetyltransferase; Dopamine

1985
Neurochemistry of dopamine in Huntington's dementia and normal aging.
    Archives of general psychiatry, 1986, Volume: 43, Issue:2

    Topics: Adult; Aged; Aging; Brain; Dementia; Dopamine; Homovanillic Acid; Humans; Huntington Disease; Male;

1986
Endurance training effects on striatal D2 dopamine receptor binding and striatal dopamine metabolites in presenescent older rats.
    Psychopharmacology, 1987, Volume: 92, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Kineti

1987
Effect of ischemia on noradrenergic and energy-related metabolites in the cerebral cortex of young and adult gerbils.
    Metabolic brain disease, 1988, Volume: 3, Issue:4

    Topics: Aging; Animals; Cerebral Cortex; Gerbillinae; Glucose; Homovanillic Acid; Ischemic Attack, Transient

1988
Effect of age on homovanillic and 4-hydroxy-3-methoxymandelic acid levels in plasma.
    European journal of pediatrics, 1986, Volume: 145, Issue:6

    Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Fetal Blood; Homovanillic Acid; Humans; Infant; I

1986
The change with age in biogenic amines and their metabolites in the striatum of the rat.
    Archives of gerontology and geriatrics, 1986, Volume: 5, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Animals; Biogenic Amines; Corpus Striatum; Dopam

1986
Effect of nialamide on the metabolism of dopamine injected into the nucleus accumbens of old rats.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Homovanillic Acid; Limbic System; Male; Mo

1986
Brain catecholamine content and turnover in aging rats.
    Experimental gerontology, 1985, Volume: 20, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; alpha-Methyltyrosine; Animals; Brain; Catecholamines; Corpus

1985