homovanillic acid has been researched along with ADDH in 34 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Levels of CSF 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), and 3-methoxy-4-hydroxyphenylglycol (MHPG), the metabolites of serotonin, dopamine, and norepinephrine, respectively, correlated significantly with behavioral measures of aggression and impulsivity/hyperactivity." | 5.07 | Cerebrospinal fluid monoamine metabolites in boys with attention-deficit hyperactivity disorder. ( Castellanos, FX; Elia, J; Gulotta, CS; Kruesi, MJ; Mefford, IN; Potter, WZ; Rapoport, JL; Ritchie, GF, 1994) |
| "Twenty boys (mean age, 9 +/- 2 years) with attention deficit disorder with hyperactivity received three weeks each of dextroamphetamine sulfate (0." | 5.06 | Fenfluramine and dextroamphetamine treatment of childhood hyperactivity. Clinical and biochemical findings. ( Donnelly, M; Keysor, CS; Murphy, DL; Oliver, J; Potter, WZ; Rapoport, JL, 1989) |
| "2 years) with Attention Deficit Disorder With Hyperactivity during an initial placebo period, after four weeks of treatment with either dextroamphetamine sulfate (N=5) or a monoamine oxidase inhibitor (N=9) and at the end of a subsequent two-week placebo "washout" period." | 5.05 | Treatment of hyperactive children with monoamine oxidase inhibitors. II. Plasma and urinary monoamine findings after treatment. ( Ismond, D; Karoum, F; Linnoila, M; Murphy, DL; Potter, WZ; Rapoport, JL; Zametkin, A, 1985) |
| " The 5-hydroxyindoleacetic acid concentration significantly predicted severity of physical aggression during follow-up." | 3.68 | A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders. Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures? ( Bartko, JJ; Hamburger, SD; Hibbs, ED; Keysor, CS; Kruesi, MJ; Rapoport, JL; Zahn, TP, 1992) |
| "Children with attention deficit disorder with hyperactivity were treated with methylphenidate HCl (0." | 3.67 | The effect of methylphenidate on urinary catecholamine excretion in hyperactivity: a partial replication. ( Hamburger, SD; Zametkin, AJ, 1988) |
| "Following the hypothesis that attention deficit disorder in adults (attention deficit disorder, residual type; ADD, RT), as well as in children, is associated with decreased central dopaminergic activity, the authors measured lumbar cerebrospinal fluid monoamine metabolites in a group of adults with ADD, RT and matched control subjects." | 2.65 | Cerebrospinal fluid homovanillic acid and 5-hydroxy-indoleacetic acid in adults with attention deficit disorder, residual type. ( Ebert, MH; Reimherr, FW; Wender, PH; Wood, DR, 1984) |
| " Urinary HVA dosage was performed on samples of urine taken after a 48-h tyrosine-free diet." | 1.27 | [Relation between auditory evoked potentials (presence, amplitude) during sound and light conditioning and levels of dopamine derivatives in infantile autism]. ( Barthelemy, C; Bruneau, N; Garreau, B; Lelord, G; Martineau, J; Tanguay, P, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (55.88) | 18.7374 |
| 1990's | 7 (20.59) | 18.2507 |
| 2000's | 7 (20.59) | 29.6817 |
| 2010's | 1 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bos, DJ | 1 |
| Oranje, B | 1 |
| Veerhoek, ES | 1 |
| Van Diepen, RM | 1 |
| Weusten, JM | 1 |
| Demmelmair, H | 1 |
| Koletzko, B | 1 |
| de Sain-van der Velden, MG | 1 |
| Eilander, A | 1 |
| Hoeksma, M | 1 |
| Durston, S | 1 |
| Rydén, E | 1 |
| Johansson, C | 1 |
| Blennow, K | 2 |
| Landén, M | 1 |
| Soderstrom, H | 1 |
| Sjodin, AK | 1 |
| Forsman, A | 1 |
| Glaser, PE | 1 |
| Surgener, SP | 1 |
| Grondin, R | 1 |
| Gash, CR | 1 |
| Palmer, M | 1 |
| Castellanos, FX | 3 |
| Gerhardt, GA | 1 |
| Coccaro, EF | 1 |
| Hirsch, SL | 1 |
| Stein, MA | 1 |
| Gerra, G | 1 |
| Leonardi, C | 1 |
| Cortese, E | 1 |
| Zaimovic, A | 1 |
| Dell'agnello, G | 1 |
| Manfredini, M | 1 |
| Somaini, L | 1 |
| Petracca, F | 1 |
| Caretti, V | 1 |
| Saracino, MA | 1 |
| Raggi, MA | 1 |
| Donnini, C | 1 |
| Hunt, RD | 2 |
| Cohen, DJ | 5 |
| Shaywitz, SE | 3 |
| Shaywitz, BA | 5 |
| Reimherr, FW | 1 |
| Wender, PH | 1 |
| Ebert, MH | 2 |
| Wood, DR | 1 |
| Leckman, JF | 2 |
| Martineau, J | 1 |
| Barthelemy, C | 1 |
| Garreau, B | 1 |
| Tanguay, P | 1 |
| Bruneau, N | 1 |
| Lelord, G | 1 |
| Shekim, WO | 4 |
| Javaid, J | 3 |
| Davis, JM | 2 |
| Bylund, DB | 2 |
| Dekirmenjian, H | 1 |
| Chapel, JL | 1 |
| Brown, GL | 1 |
| Rapoport, JL | 8 |
| Sullivan, CM | 1 |
| Anderson, GM | 2 |
| Gillespie, SM | 1 |
| Sullivan, B | 1 |
| Elia, J | 3 |
| Kruesi, MJ | 5 |
| Gulotta, CS | 2 |
| Mefford, IN | 2 |
| Potter, WZ | 7 |
| Ritchie, GF | 2 |
| Marsh, WL | 1 |
| Hamburger, SD | 5 |
| Grayson, RH | 1 |
| Halperin, JM | 2 |
| Sharma, V | 1 |
| Schwartz, ST | 2 |
| Koda, VH | 1 |
| Newcorn, JH | 2 |
| Pick, LH | 1 |
| Oades, RD | 1 |
| Zhuang, X | 1 |
| Oosting, RS | 1 |
| Jones, SR | 1 |
| Gainetdinov, RR | 1 |
| Miller, GW | 1 |
| Caron, MG | 1 |
| Hen, R | 1 |
| Moskowitz, MA | 1 |
| Wurtman, RJ | 1 |
| Bowers, MB | 2 |
| Caparulo, BK | 1 |
| Hibbs, ED | 1 |
| Zahn, TP | 1 |
| Keysor, CS | 3 |
| Bartko, JJ | 1 |
| Borcherding, BG | 1 |
| Zametkin, A | 1 |
| Murphy, DL | 2 |
| Linnoila, M | 1 |
| Karoum, F | 1 |
| Ismond, D | 1 |
| Swedo, SE | 2 |
| Rogeness, GA | 1 |
| Maas, JW | 1 |
| Javors, MA | 1 |
| Macedo, CA | 1 |
| Fischer, C | 1 |
| Harris, WR | 1 |
| Leonard, HL | 1 |
| Cheslow, DL | 1 |
| Stipetic, M | 1 |
| Donnelly, M | 1 |
| Oliver, J | 1 |
| Zametkin, AJ | 1 |
| Riddle, MA | 1 |
| Hardin, MT | 1 |
| Ort, SI | 1 |
| Sinclair, E | 1 |
| Glaser, R | 1 |
| Horwitz, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Eicosapentaenoic Acid (EPA)/ Docosahexaenoic Acid (DHA) Supplementation on Cognitive Control in Children With Attention Deficit Hyperactivity Disorder (ADHD)[NCT01554462] | 79 participants (Actual) | Interventional | 2009-01-31 | Completed | |||
| [NCT00004325] | 200 participants | Observational | 1988-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for homovanillic acid and ADDH
| Article | Year |
|---|---|
Recent advances in Gilles de la Tourette syndrome: implications for clinical practice and future research.
Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Compulsive | 1983 |
Catecholamines and neurologic diseases (second of two parts).
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Brain Diseases; Catecholamines; Cereb | 1975 |
8 trials available for homovanillic acid and ADDH
| Article | Year |
|---|---|
Reduced Symptoms of Inattention after Dietary Omega-3 Fatty Acid Supplementation in Boys with and without Attention Deficit/Hyperactivity Disorder.
Topics: Adolescent; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Brain; Case-Control | 2015 |
Cerebrospinal fluid homovanillic acid and 5-hydroxy-indoleacetic acid in adults with attention deficit disorder, residual type.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Clinical Trials as Topic; Double-Blind Method; | 1984 |
Aspartame, behavior, and cognitive function in children with attention deficit disorder.
Topics: Adolescent; Aspartame; Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Child B | 1994 |
Cerebrospinal fluid monoamine metabolites in boys with attention-deficit hyperactivity disorder.
Topics: Aggression; Attention; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Doub | 1994 |
Cerebrospinal fluid homovanillic acid predicts behavioral response to stimulants in 45 boys with attention deficit/hyperactivity disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Behavior; Biogenic Monoamines; Central Nervous System | 1996 |
Stimulant drug treatment of hyperactivity: biochemical correlates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetam | 1990 |
Treatment of hyperactive children with monoamine oxidase inhibitors. II. Plasma and urinary monoamine findings after treatment.
Topics: Amines; Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; Clorgyline; | 1985 |
Fenfluramine and dextroamphetamine treatment of childhood hyperactivity. Clinical and biochemical findings.
Topics: Attention Deficit Disorder with Hyperactivity; Blood Platelets; Child; Clinical Trials as Topic; Dex | 1989 |
24 other studies available for homovanillic acid and ADDH
| Article | Year |
|---|---|
Lower CSF HVA and 5-HIAA in bipolar disorder type 1 with a history of childhood ADHD.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Female; Follow-Up Studies; H | 2009 |
New evidence for an association between the CSF HVA:5-HIAA ratio and psychopathic traits.
Topics: Adolescent; Adult; Age of Onset; Aggression; Antisocial Personality Disorder; Attention Deficit Diso | 2003 |
Cerebellar neurotransmission in attention-deficit/hyperactivity disorder: does dopamine neurotransmission occur in the cerebellar vermis?
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; | 2006 |
Plasma homovanillic acid correlates inversely with history of learning problems in healthy volunteer and personality disordered subjects.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Diagnostic and Statistical Manual of Me | 2007 |
Homovanillic acid (HVA) plasma levels inversely correlate with attention deficit-hyperactivity and childhood neglect measures in addicted patients.
Topics: Adult; Antisocial Personality Disorder; Anxiety; Attention Deficit Disorder with Hyperactivity; Chil | 2007 |
Strategies for study of the neurochemistry of attention deficit disorder in children.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Dopamine beta-Hydroxylase; Growth H | 1982 |
[Relation between auditory evoked potentials (presence, amplitude) during sound and light conditioning and levels of dopamine derivatives in infantile autism].
Topics: Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child; Conditioning, Psychological | 1984 |
Urinary MHPG and HVA excretion in boys with attention deficit disorder and hyperactivity treated with d-amphetamine.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Glycols; Homovanillic Acid; | 1983 |
Effects of d-amphetamine on urinary metabolites of dopamine and norepinephrine in hyperactive boys.
Topics: Attention Deficit Disorder with Hyperactivity; Brain; Child; Dextroamphetamine; Dopamine; Glycols; H | 1982 |
Urinary 3-methyoxy-4-hydroxyphenylglycol and homovanillic acid response to d-amphetamine in hyperactive children.
Topics: Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Circadian Rhythm; Dextroamphet | 1981 |
Changes in plasma prolactin and catecholamine metabolite levels following acute needle stick in children.
Topics: Attention Deficit Disorder with Hyperactivity; Catheters, Indwelling; Child; Homovanillic Acid; Huma | 1997 |
A longitudinal study of neurobiological mechanisms in boys with attention-deficit hyperactivity disorder: preliminary findings.
Topics: Aging; Attention Deficit Disorder with Hyperactivity; Blood Platelets; Brain; Catecholamines; Child; | 1999 |
Differential measures of 'sustained attention' in children with attention-deficit/hyperactivity or tic disorders: relations to monoamine metabolism.
Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Biogenic Monoamines; Case-Cont | 2000 |
Hyperactivity and impaired response habituation in hyperdopaminergic mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Apomorphine; Attention Deficit Disorder with | 2001 |
CSF monoamine metabolites in children with minimal brain dysfunction: evidence for alteration of brain dopamine. A preliminary report.
Topics: Attention Deficit Disorder with Hyperactivity; Biogenic Amines; Brain; Child; Child, Preschool; Dopa | 1977 |
Dopamine and serotonin metabolism in neuropsychiatrically disturbed children. CSF homovanillic acid and 5-hydroxyindoleacetic acid.
Topics: Adolescent; Age Factors; Aphasia; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; | 1977 |
A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders. Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures?
Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorde | 1992 |
Concentration gradient of CSF monoamine metabolites in children and adolescents.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Child De | 1988 |
Attention deficit disorder symptoms and urine catecholamines.
Topics: Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Dopamine; Dopamine beta-Hydrox | 1989 |
Lack of seasonal variation in pediatric lumbar cerebrospinal fluid neurotransmitter metabolite concentrations.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Female; | 1989 |
Pathophysiology of ADDH.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Homovanillic Acid; Humans; Male; Neurotransmit | 1988 |
The effect of methylphenidate on urinary catecholamine excretion in hyperactivity: a partial replication.
Topics: 3,4-Dihydroxyphenylacetic Acid; Attention Deficit Disorder with Hyperactivity; Catecholamines; Child | 1988 |
Brief debrisoquin administration to assess central dopaminergic function in children.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Debrisoquin; Dopamine; Female; Hom | 1986 |
Norepinephrine and dopamine metabolites and educational variables in boys with attention deficit disorder and hyperactivity.
Topics: Achievement; Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Glycols; Homovanillic | 1987 |