Compounds > homoserine

homoserine and Cystic Fibrosis

homoserine has been researched along with Cystic Fibrosis in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's4 (40.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rousseau, S; Roussel, L1
Grauer, DC; Janda, KD; Katz, AZ; Kaufmann, GF; Kravchenko, VV; Lehmann, M; Mathison, JC; Meijler, MM; Scott, DA; Ulevitch, RJ1
Barrett, DA; Cámara, M; Cifelli, PM; Erskine, P; Givskov, M; Holland, ED; Knox, A; Lewis, S; Ortori, CA; Righetti, K; Smyth, AR; Williams, P1
Field, TR; Parkins, MD; Rabin, HR; Sibley, CD; Surette, MG1
Blohmke, CJ; Hancock, RE; Mayer, ML; Sheridan, JA; Turvey, SE1
Imperi, F; Leoni, L; Massai, F; Quattrucci, S; Visca, P; Zennaro, E1
Dammel, C; Duan, K; Rabin, H; Stein, J; Surette, MG1
Chambers, CE; Schwab, U; Sokol, PA; Visser, MB1
Brun, P; Figarella, C; Kammouni, W; Lazdunski, A; Marchand-Pinatel, S; Merten, MD; Saleh, A; Tubul, A1
Blanc, D; Favre-Bonté, S; Pache, JC; Pechère, JC; Robert, J; van Delden, C1

Trials

1 trial(s) available for homoserine and Cystic Fibrosis

ArticleYear
Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial.
    Pediatric pulmonology, 2010, Volume: 45, Issue:4

    Topics: 4-Butyrolactone; Adolescent; Adult; Child; Cystic Fibrosis; Female; Garlic; Homoserine; Humans; Male; Middle Aged; Phytotherapy; Pilot Projects; Plant Oils; Plasma; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Respiratory Function Tests; Sputum; Treatment Outcome; Young Adult

2010

Other Studies

9 other study(ies) available for homoserine and Cystic Fibrosis

ArticleYear
Exposure of airway epithelial cells to Pseudomonas aeruginosa biofilm-derived quorum sensing molecules decrease the activity of the anti-oxidant response element bound by NRF2.
    Biochemical and biophysical research communications, 2017, 02-05, Volume: 483, Issue:2

    Topics: 4-Butyrolactone; Antioxidant Response Elements; Biofilms; Cell Line; Cystic Fibrosis; Epithelial Cells; Gene Expression Regulation; Heme Oxygenase-1; Homoserine; Humans; Interleukin-8; Lung; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing

2017
Modulation of gene expression via disruption of NF-kappaB signaling by a bacterial small molecule.
    Science (New York, N.Y.), 2008, Jul-11, Volume: 321, Issue:5886

    Topics: 4-Butyrolactone; Adult; Animals; Cyclic AMP Response Element-Binding Protein; Cystic Fibrosis; Female; Gene Expression Regulation; Homoserine; Humans; I-kappa B Kinase; I-kappa B Proteins; Immunity, Innate; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Pseudomonas aeruginosa; Pseudomonas Infections; Signal Transduction; Toll-Like Receptors; Transcription Factor RelA

2008
The genus Prevotella in cystic fibrosis airways.
    Anaerobe, 2010, Volume: 16, Issue:4

    Topics: Adult; Bacterial Typing Techniques; beta-Lactamases; Cluster Analysis; Colony Count, Microbial; Cystic Fibrosis; DNA, Bacterial; DNA, Ribosomal; Homoserine; Humans; Lactones; Prevotella; Respiratory System; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Sputum

2010
The Pseudomonas aeruginosa autoinducer 3O-C12 homoserine lactone provokes hyperinflammatory responses from cystic fibrosis airway epithelial cells.
    PloS one, 2011, Jan-31, Volume: 6, Issue:1

    Topics: 4-Butyrolactone; Calcium; Cystic Fibrosis; Cytokines; Epithelial Cells; Homoserine; Humans; Inflammation; Lactones; Pseudomonas aeruginosa; Respiratory System

2011
A multitask biosensor for micro-volumetric detection of N-3-oxo-dodecanoyl-homoserine lactone quorum sensing signal.
    Biosensors & bioelectronics, 2011, Apr-15, Volume: 26, Issue:8

    Topics: 4-Butyrolactone; Biosensing Techniques; Cystic Fibrosis; High-Throughput Screening Assays; Homoserine; Humans; Pseudomonas aeruginosa; Quorum Sensing; Sputum

2011
Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication.
    Molecular microbiology, 2003, Volume: 50, Issue:5

    Topics: Animals; Bacterial Proteins; Cystic Fibrosis; Disease Models, Animal; Gene Expression Regulation, Bacterial; Homoserine; Humans; Lactones; Lung; Oropharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Signal Transduction; Sputum; Staphylococcus; Streptococcus; Virulence

2003
Identification of N-acylhomoserine lactones in mucopurulent respiratory secretions from cystic fibrosis patients.
    FEMS microbiology letters, 2005, Mar-15, Volume: 244, Issue:2

    Topics: Burkholderia cepacia; Cystic Fibrosis; Homoserine; Humans; Lactones; Pseudomonas aeruginosa; Signal Transduction; Sputum

2005
Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone inhibits expression of P2Y receptors in cystic fibrosis tracheal gland cells.
    Infection and immunity, 1999, Volume: 67, Issue:10

    Topics: 4-Butyrolactone; Cell Line; Cystic Fibrosis; Homoserine; Humans; Ibuprofen; Pseudomonas aeruginosa; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Trachea

1999
Detection of Pseudomonas aeruginosa cell-to-cell signals in lung tissue of cystic fibrosis patients.
    Microbial pathogenesis, 2002, Volume: 32, Issue:3

    Topics: 4-Butyrolactone; Adult; Bronchi; Cystic Fibrosis; Female; Homoserine; Humans; Lung; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Signal Transduction

2002