homoharringtonine and Corneal-Opacity

homoharringtonine has been researched along with Corneal-Opacity* in 1 studies

Other Studies

1 other study(ies) available for homoharringtonine and Corneal-Opacity

ArticleYear
Effect of Homoharringtonine on corneal haze after excimer laser photorefractive keratectomy in rabbits.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005, Volume: 25, Issue:6

    To evaluate the inhibiting effect of Homoharringtonine (HHT) on the corneal haze after excimer laser photorefractive keratectomy (PRK) in rabbits. 18 healthy rabbits which underwent PRK were randomly divided into three groups (A, B and C). The refractive degree of ablation was - 10.0DS in each group. Group A was locally treated with a piece of filter paper soaked with 1 mg/mL HHT for 5 min, and then the entire cornea was repeatedly irrigated with balance solution; Group B was dropped with 0.1 mg/mL HHT after PRK for 3 months; Group C was the control group. Corneal haze, histopathology, response, ect. were investigated. The corneal haze was significantly less in group A, while the difference between group B and group C was insignificant. Keratocytes and fibrocytes in corneal stroma were more active up to 3 months in group B and group C. Intraoperative use of topical HHT can reduce corneal haze after PRK in rabbits.

    Topics: Animals; Corneal Opacity; Endothelium, Corneal; Harringtonines; Homoharringtonine; Lasers, Excimer; Myopia; Photorefractive Keratectomy; Rabbits; Random Allocation

2005