homogentisic acid has been researched along with Protein Aggregation, Pathological in 1 studies
Homogentisic Acid: Dihydroxyphenylacetic acid with hydroxyls at the 2 and 5 positions of the phenyl ring.
homogentisic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents at the 2- and 5-positions.
Protein Aggregation, Pathological: A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alkaptonuria (AKU) is an ultra-rare inborn error of metabolism characterized by homogentisic acid (HGA) accumulation due to a deficient activity of the homogentisate 1." | 3.85 | Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins. ( Bernardini, G; Bernini, A; Braconi, D; Lupetti, P; Marzocchi, B; Millucci, L; Niccolai, N; Santucci, A; Spiga, O, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braconi, D | 1 |
| Millucci, L | 1 |
| Bernini, A | 1 |
| Spiga, O | 1 |
| Lupetti, P | 1 |
| Marzocchi, B | 1 |
| Niccolai, N | 1 |
| Bernardini, G | 1 |
| Santucci, A | 1 |
1 other study available for homogentisic acid and Protein Aggregation, Pathological
| Article | Year |
|---|---|
Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins.
Topics: Alkaptonuria; alpha-Synuclein; Amyloid beta-Peptides; Amyloidogenic Proteins; Amyloidosis; Atrial Na | 2017 |