homogentisic acid has been researched along with Chronic Disease in 5 studies
Homogentisic Acid: Dihydroxyphenylacetic acid with hydroxyls at the 2 and 5 positions of the phenyl ring.
homogentisic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents at the 2- and 5-positions.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| " A diagnosis of ochronosis was made by the observation of bluish-brown pigmentation in the nose and ears, dark urine colors following alkalization, and high levels of homogentisic acid in the urine." | 4.84 | Ochronosis in differential diagnosis of patients with chronic backache: a review of the literature. ( Capkin, E; Karkucak, M; Serdaroğlu, M; Tosun, M; Yayli, S, 2007) |
| " The finding of a massively elevated excretion of homogentisic acid (HGA) in the patient's urine confirmed the suspicion that the complaints were due to underlying alkaptonuria." | 3.76 | A metabolic cause of spinal deformity. ( Effelsberg, NM; Hügle, T; Walker, UA, 2010) |
| " Similarly, Fah(-/-) animals with liver injury were also resistant to apoptosis induced by the Fas ligand Jo-2 and to necrosis-like cell death induced by acetaminophen (APAP)." | 3.72 | Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death. ( Al-Dhalimy, M; Finegold, M; Grompe, M; Groopman, J; Iordanov, MS; Ou, CN; Ryabinina, O; van Den Berg, IE; Vogel, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Effelsberg, NM | 1 |
| Hügle, T | 1 |
| Walker, UA | 1 |
| Vogel, A | 1 |
| van Den Berg, IE | 1 |
| Al-Dhalimy, M | 2 |
| Groopman, J | 1 |
| Ou, CN | 1 |
| Ryabinina, O | 1 |
| Iordanov, MS | 1 |
| Finegold, M | 2 |
| Grompe, M | 2 |
| Held, PK | 1 |
| Willenbring, H | 1 |
| Akkari, Y | 1 |
| Jiang, S | 1 |
| Torimaru, Y | 1 |
| Olson, S | 1 |
| Fleming, WH | 1 |
| Capkin, E | 1 |
| Karkucak, M | 1 |
| Yayli, S | 1 |
| Serdaroğlu, M | 1 |
| Tosun, M | 1 |
| Ivanova, VD | 1 |
| Baĭkova, VN | 1 |
| Raushenbakh, MO | 1 |
1 review available for homogentisic acid and Chronic Disease
| Article | Year |
|---|---|
Ochronosis in differential diagnosis of patients with chronic backache: a review of the literature.
Topics: Alkaptonuria; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Ascorbic Acid; Back Pain; Calcino | 2007 |
4 other studies available for homogentisic acid and Chronic Disease
| Article | Year |
|---|---|
A metabolic cause of spinal deformity.
Topics: Adult; Alkaptonuria; Chronic Disease; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Low | 2010 |
Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Cell Survival; Central Nervous System D | 2004 |
In vivo genetic selection of renal proximal tubules.
Topics: Acute Disease; Animals; Bone Marrow Transplantation; Cell Differentiation; Cell Fusion; Chronic Dise | 2006 |
[Mechanism of formation of the blastomogenic metabolite of tyrosine - P-hydroxyphenyllactic acid in hemoblastoses].
Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Homogentisic Acid; Humans; Lactates; Leukem | 1978 |