homogentisic acid has been researched along with Arthritis in 10 studies
Homogentisic Acid: Dihydroxyphenylacetic acid with hydroxyls at the 2 and 5 positions of the phenyl ring.
homogentisic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents at the 2- and 5-positions.
Arthritis: Acute or chronic inflammation of JOINTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The metabolic disorder, alkaptonuria, is distinguished by elevated serum levels of 2,5-dihydroxyphenylacetic acid (homogentisic acid), pigmentation of cartilage and connective tissue and, ultimately, the development of inflammatory arthritis." | 7.67 | Homogentisic acid autoxidation and oxygen radical generation: implications for the etiology of alkaptonuric arthritis. ( Batkoff, B; Martin, JP, 1987) |
| "Increased circulating homogentisic acid in body fluids occurs in alkaptonuria (AKU) due to lack of enzyme homogentisate dioxygenase leading in turn to conversion of HGA to a pigmented melanin-like polymer, known as ochronosis." | 3.77 | Natural history of alkaptonuria revisited: analyses based on scoring systems. ( Cox, TF; Ranganath, LR, 2011) |
| " Urine homogentisic acid level was elevated, which is diagnostic for alkaptonuria." | 3.76 | Alkaptonuria. ( Anolik, R; Pomeranz, MK; Yancovitz, M, 2010) |
| "The metabolic disorder, alkaptonuria, is distinguished by elevated serum levels of 2,5-dihydroxyphenylacetic acid (homogentisic acid), pigmentation of cartilage and connective tissue and, ultimately, the development of inflammatory arthritis." | 3.67 | Homogentisic acid autoxidation and oxygen radical generation: implications for the etiology of alkaptonuric arthritis. ( Batkoff, B; Martin, JP, 1987) |
| "Alcaptonuria is a rare (incidence approx." | 1.29 | [Alkaptonuria and ochronotic arthropathy. Arthroscopic and intraoperative findings in implantation of a knee joint surface replacing prosthesis]. ( Lubinus, HH; Lubinus, P; Ramsperger, R, 1994) |
| "Homogentisic acid was detectable in the urine by thin layer chromatography, and asymptomatic spondylosis with intervertebral disc calcification was found." | 1.27 | Knee arthropathy in ochronosis: diagnosis by arthroscopy with ultrastructural features. ( Lurie, DP; Musil, G, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Tarawneh, A | 1 |
| Al-Limoun, M | 1 |
| Khlaifat, AM | 1 |
| Tarawneh, I | 1 |
| Mwafi, N | 1 |
| Khleifat, K | 1 |
| Alqaraleh, M | 1 |
| Mizher, H | 1 |
| Yancovitz, M | 1 |
| Anolik, R | 1 |
| Pomeranz, MK | 1 |
| Ranganath, LR | 1 |
| Cox, TF | 1 |
| Vagts, DA | 1 |
| Beck, CE | 1 |
| Lurie, DP | 1 |
| Musil, G | 1 |
| Ramsperger, R | 1 |
| Lubinus, P | 1 |
| Lubinus, HH | 1 |
| Takita, H | 1 |
| Schumacher, HR | 1 |
| Holdsworth, DE | 1 |
| Martin, JP | 1 |
| Batkoff, B | 1 |
| Alcalá, O | 1 |
| Alarcón-Corredor, OM | 1 |
| Sánchez de Molina, D | 1 |
1 review available for homogentisic acid and Arthritis
| Article | Year |
|---|---|
[Alkaptonuria (homogentisic aciduria)].
Topics: Alkaptonuria; Arthritis; Diagnosis, Differential; Dioxygenases; Homogentisate 1,2-Dioxygenase; Homog | 1998 |
9 other studies available for homogentisic acid and Arthritis
| Article | Year |
|---|---|
Bacterial quality of urinary tract in patients with alkaptonuria.
Topics: Alkaptonuria; Arthritis; Female; Homogentisic Acid; Humans; Male; Urinary Tract | 2023 |
Alkaptonuria.
Topics: Aged; Alkaptonuria; Arthritis; Cyclohexanones; Female; Homogentisic Acid; Humans; Joint Diseases; Ni | 2010 |
Natural history of alkaptonuria revisited: analyses based on scoring systems.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Adult; Aged; Aged, 80 and over; Alkaptonuria; Arthr | 2011 |
[Perioperative management of a patient with alcaptonuria--a case report].
Topics: Aged; Amino Acid Metabolism, Inborn Errors; Anesthesia, General; Arthritis; Female; Homogentisic Aci | 2004 |
Knee arthropathy in ochronosis: diagnosis by arthroscopy with ultrastructural features.
Topics: Arthritis; Arthroscopy; Chromatography, Thin Layer; Female; Homogentisic Acid; Humans; Knee Joint; M | 1984 |
[Alkaptonuria and ochronotic arthropathy. Arthroscopic and intraoperative findings in implantation of a knee joint surface replacing prosthesis].
Topics: Alkaptonuria; Arthritis; Female; Homogentisic Acid; Humans; Knee Prosthesis; Middle Aged; Ochronosis | 1994 |
Ochronotic arthropathy. I. Clinicopathologic studies.
Topics: Adult; Alkaptonuria; Arthritis; Cartilage, Articular; Female; Homogentisic Acid; Humans; Male; Middl | 1977 |
Homogentisic acid autoxidation and oxygen radical generation: implications for the etiology of alkaptonuric arthritis.
Topics: Alkaptonuria; Animals; Arthritis; Ascorbic Acid; Edetic Acid; Free Radicals; Homogentisic Acid; Hyal | 1987 |
[Alkaptonuria. Presentation of a case in a 2-year-old child].
Topics: Alkaptonuria; Amino Acids; Arthritis; Cerumen; Diabetes Mellitus; Diagnosis, Differential; Homogenti | 1986 |