homogentisic acid has been researched along with Amyloidosis in 3 studies
Homogentisic Acid: Dihydroxyphenylacetic acid with hydroxyls at the 2 and 5 positions of the phenyl ring.
homogentisic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents at the 2- and 5-positions.
Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alkaptonuria (AKU) is an ultra-rare inborn error of metabolism characterized by homogentisic acid (HGA) accumulation due to a deficient activity of the homogentisate 1." | 3.85 | Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins. ( Bernardini, G; Bernini, A; Braconi, D; Lupetti, P; Marzocchi, B; Millucci, L; Niccolai, N; Santucci, A; Spiga, O, 2017) |
| "Alkaptonuria (AKU) is an ultra-rare disease developed from the lack of homogentisic acid oxidase activity, causing homogentisic acid (HGA) accumulation that produces a HGA-melanin ochronotic pigment, of unknown composition." | 3.78 | Alkaptonuria is a novel human secondary amyloidogenic disease. ( Amato, L; Benucci, M; Bernardini, G; Braconi, D; Chellini, F; Galeazzi, M; Ghezzi, L; Laschi, M; Lupetti, P; Mannoni, A; Millucci, L; Orlandini, M; Paccagnini, E; Santucci, A; Selvi, E; Spreafico, A; Tinti, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braconi, D | 2 |
| Millucci, L | 3 |
| Bernini, A | 1 |
| Spiga, O | 1 |
| Lupetti, P | 2 |
| Marzocchi, B | 1 |
| Niccolai, N | 1 |
| Bernardini, G | 3 |
| Santucci, A | 3 |
| Mitri, E | 1 |
| Merolle, L | 1 |
| Vaccari, L | 1 |
| Gianoncelli, A | 1 |
| Spreafico, A | 1 |
| Tinti, L | 1 |
| Ghezzi, L | 1 |
| Paccagnini, E | 1 |
| Amato, L | 1 |
| Laschi, M | 1 |
| Selvi, E | 1 |
| Galeazzi, M | 1 |
| Mannoni, A | 1 |
| Benucci, M | 1 |
| Chellini, F | 1 |
| Orlandini, M | 1 |
3 other studies available for homogentisic acid and Amyloidosis
| Article | Year |
|---|---|
Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins.
Topics: Alkaptonuria; alpha-Synuclein; Amyloid beta-Peptides; Amyloidogenic Proteins; Amyloidosis; Atrial Na | 2017 |
A new light on Alkaptonuria: A Fourier-transform infrared microscopy (FTIRM) and low energy X-ray fluorescence (LEXRF) microscopy correlative study on a rare disease.
Topics: Alkaptonuria; Amyloidosis; Cartilage; Fluorescence; Homogentisic Acid; Humans; Lipids; Magnesium; Mi | 2017 |
Alkaptonuria is a novel human secondary amyloidogenic disease.
Topics: Aged; Alkaptonuria; Amyloidosis; Cartilage; Chondrocytes; Female; Homogentisate 1,2-Dioxygenase; Hom | 2012 |