Compounds > homocysteine

homocysteine and Stroke

homocysteine has been researched along with Stroke in 482 studies

Research

Studies (482)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (1.04)18.2507
2000's236 (48.96)29.6817
2010's192 (39.83)24.3611
2020's49 (10.17)2.80

Authors

AuthorsStudies
Satoh, M1
Bao, H; Cheng, X; Hu, F; Huang, X; Li, J; Wang, T; Yu, S; Zhou, W1
Chen, XR; Huang, LW; Li, J; Li, LL; Yu, M1
Hu, Q; Shen, S; Wang, J; Zhao, Q1
Liang, X; Liu, H; Luo, S; Sai, N; Wang, M; Wang, X; Zhang, Q; Zhang, X1
Mr, R; Paul, K1
Atam, V; Chauhan, H; Reddy, DH; Sawlani, KK1
Bang, OY; Choi, JC; Choi, KH; Chung, JW; Heo, SH; Hwang, YH; Jung, JM; Kim, BJ; Kim, CK; Kim, GM; Kim, JM; Kim, JT; Kim, YJ; Nam, KW; Oh, K; Park, JH; Park, KY; Park, MS; Seo, WK; Song, TJ; Yu, S1
He, P; Huang, X; Wu, L1
Chen, Y; Peng, M; Zou, H1
Hankey, GJ; Spence, JD1
Duan, Z; Fang, Q; Hou, H; Sun, G; Tao, L; Zhang, S1
Braekkan, SK; Hansen, JB; Morelli, VM; Tøndel, BG1
Bottiglieri, T; Gu, H; Jadavji, NM; Jasbi, P; Kwatra, N; North, S; Pascual, AS; Poole, J; Weissig, V1
Ames, PRJ; Arcaro, A; D'Andrea, G; Gentile, F; Iannaccone, L; Maraglione, M; Marottoli, V1
Chen, Y; Ye, M1
Hu, Y; Li, F; Yang, Y; Yuan, S; Zhang, T; Zhao, X1
Chang, ST; Hsieh, SP; Li, SA; Lin, YP1
Bu, X; Chen, J; Guo, D; He, J; Kelly, TN; Li, C; Peng, H; Shan, G; Shen, C; Shi, M; Sun, X; Sun, Y; Wang, A; Xu, T; Zhang, Y; Zhao, J; Zhong, C; Zhu, Z1
Cong, M; Hu, Y; Jin, M; Li, X; Lin, C; Liu, J; Niu, J; Qiu, C; Wang, N; Wu, N; Zhang, H; Zhang, K; Zhou, J1
Farias Vidigal Nascimento, R; Figueiredo, EG; Gusmão, RC; Pipek, LZ; Rabelo, NN; Teixeira, MJ; Telles, JPM1
Chen, C; Ding, L; Guo, J; Liu, H; Ma, Y; Qiao, X; Wang, J; Wang, M; Yang, T; Zhao, S1
Tunc, Z; Yurekli, UF1
Xu, B; Yang, L1
Hou, HM; Qin, XJ; Zhao, HY1
Gu, HQ; Li, H; Li, ZX; Liu, W; Ma, XL; Wang, YJ1
Chen, B; Chen, M; Fu, Y; Hu, S; Lv, J; Xu, Z; Yan, X; Zhang, M; Zhao, N1
Chandratheva, A; Chen, J; Coughlan, CH; Goodison, W; Murphy, E; Rees, A1
Bao, H; Chen, G; Cheng, X; Cheng, Z; Cui, Y; Ding, C; Hu, L; Huang, X; Huo, Y; Li, P; Qin, X; Sheng, C; Song, D; Tang, G; Wang, J; Wang, X; Wang, Z; Yao, C; Zhang, J1
Palma Reis, R1
Alves, M; Guerreiro, L; Rosado Julião, S1
Yang, J; Zhang, S1
Cai, J; Cai, Y; Dai, W; Ge, J; Guo, Y; Jiang, B; Li, D; Li, J; Li, Y; Liu, G; Qiu, E; Wang, Y; Xu, J; Yao, C; Yao, G; Zhang, R; Zhang, Y; Zhao, X1
Gao, L; Song, J; Xu, C; Zhang, J1
Bucciantini, M; Caselli, A; Garagna, S; Giorgetti, S; Leri, M; Luti, S; Marchese, L; Natalello, A; Paoli, P; Rebuzzini, P; Stefani, M1
Li, H; Li, J; Lin, J; Liu, L; Wang, A; Wang, Y; Zhao, X; Zuo, Z1
Rai, PS; Satyamoorthy, K; Sharma, AR; Shashikiran, U; Shetty, R; Uk, AR1
Kabi, BC; Saini, RP; Saluja, S1
Cheng, Y; Hou, J; Jiang, Y; Li, J; Ma, Y; Man, Z; Su, X; Sun, L; Tian, M; Tie, T; Zhang, S; Zhang, T; Zhang, Y1
Du, X; Li, K; Liang, L; Liu, Z; Song, L; Sun, R; Xiao, L1
Du, B; Huang, X; Li, D; Ren, B; Yue, L; Zhang, C; Zhang, W; Zhao, Q1
Chen, L; Fang, X; Li, Q; Min, J; Wang, F; Wang, X1
Cao, J; Chen, Y; Feng, Y; Kang, K; Wang, W; Xue, Q1
Ivanov, AV; Kubatiev, AA; Maksimova, MY; Nikiforova, KA; Ochtova, FR; Piradov, MA; Suanova, ET; Virus, ED1
Azarpazhooh, MR; Bogiatzi, C; Hankey, GJ; Larsson, SC; Spence, JD1
Spence, JD10
Refsum, H; Smith, AD1
Bjørklund, G; Chirumbolo, S; Dadar, M; Lenchyk, L; Lozynska, I; Lysiuk, R; Peana, M; Severin, B; Upyr, T1
Fan, Y; Huang, J; Zhang, H; Zhou, Y1
O'Suilleabhain, P1
Buonanno, FS; Deng, W; Inglessis-Azuaje, I; Lo, EH; Locascio, JJ; McMullin, D; Ning, M; Palacios, IF1
Cai, Y; Cheng, X; Fu, J; He, M; Hou, FF; Huang, X; Huo, Y; Li, J; Qin, X; Sun, N; Tang, G; Wang, B; Wang, X; Zhao, M1
Cao, Y; Jiang, Y; Kong, X; Li, P; Liu, Q; Ma, L; Yan, M; Zhang, H; Zhao, H; Zhao, T1
Markišić, M; Pavlović, AM; Pavlović, DM1
Cheng, LS; Ji, K; Shen, Y; Tu, WJ; Zhang, LJ1
Kang, MJ; Lee, H; Lee, YB; Park, HM; Park, KH; Shin, DH; Shin, DJ; Sung, YH; Yang, JW1
Li, ZZ; Qiao, HJ; Sun, W; Wang, B; Wang, LM; Yu, JC1
Bobby, Z; NithinKumar, U; Srilatha, K; Subrahmanyam, DK1
Banecka-Majkutewicz, Z; Banecki, B; Bloch, S; Gabig-Cimińska, M; Grabowski, M; Jakóbkiewicz-Banecka, J; Kadziński, L; Kaźmierkiewicz, R; Węgrzyn, A; Węgrzyn, G1
Christopher, R; Majumdar, V; Nagaraja, D; Rudreshkumar, KJ1
Klironomos, S; Kostulas, K; Markaki, I; Sjostrand, C1
Chen, S; Cheng, M; Dong, Z; Huang, G; Liu, H; Sai, N; Wang, M; Wang, X; Zhang, X; Zhao, Y1
Kim, J; Kim, JO; Kim, NK; Kim, OJ; Oh, SH; Park, HS; Ryu, CS; Shin, JW1
Jin, G1
Bao, H; Chen, Y; Cheng, X; Cui, Y; He, M; Hou, FF; Huang, X; Huang, Y; Huo, Y; Li, J; Li, P; Li, Y; Qin, X; Sun, N; Tang, G; Wang, B; Wang, J; Yin, D; Zhang, Y1
Dong, JZ; Ma, CS; Shang, MS; Yao, Y1
Bu, X; Chen, CS; Chen, J; Cui, Y; Guo, L; He, J; Ju, Z; Li, D; Wang, X; Xu, T; Yin, J; Zhang, J; Zhang, Y; Zhong, C; Zhu, Z1
Cui, BB; Fu, RL; Geng, HH; Jin, YP; Li, B; Wang, JJ; Wang, PX; Wang, Q; Zhang, Q1
Cao, X; He, Y; Li, A; Li, Q; Shi, Y; Xu, L; Zhang, Y; Zhao, H; Zhao, X; Zheng, H1
Guo, F; Liang, Y; Qu, H; Teng, W; Zhao, C; Zhao, M; Zhou, Z1
Chi, H; Li, J; Li, Y; Liu, X; Wang, J; Wang, L; Yang, D; Zheng, Q1
Fu, Q; Han, B; Hao, L; Pang, H; Zong, Z1
Abur, U; Avci, B; Gungor, L; Ozberk, MB; Polat, M1
He, W; Hua, J; Shi, J; Wang, Y1
Gong, L; Liu, W; Liu, X; Wu, J; Xie, J; Zhao, Y1
Guan, Y; Ji, Y; Li, M; Liu, S; Lu, H; Shi, Z; Xue, J; Yue, W; Zhang, B; Zhang, M1
Cheng, X; Hou, FF; Huang, X; Huo, Y; Kong, X; Li, J; Li, P; Liu, L; Qin, X; Song, Y; Tang, G; Wang, B; Wang, X; Xu, B; Xu, R; Yang, W; Yu, Y; Zhang, J; Zhang, Y; Zhao, M; Zhao, S1
Hachinski, V; Spence, JD1
Lin, YY; Liu, XH; Liu, XY; Ma, XY; Xie, JC; Yu, J; Zhao, YC; Zhao, YX1
Chrysant, GS; Chrysant, SG1
Bo, F; Chen, H; Chen, YC; Geng, W; Jiang, L; Mao, CN; Yin, X; Zhang, H1
Emmerson, JT; Jadavji, NM; MacFarlane, AJ; Shanmugalingam, U; Smith, PD; Willmore, WG1
Tan, S; Wang, B; Yuan, M1
Kan, P; Wang, J; Xiang, L; Xu, N; Yang, P; Yao, X; Zhu, Y1
Guo, X; Mahara, G; Ping, Z; Tao, LX; Wu, J; Yang, K; Zhang, J; Zhang, JB1
Ban, Q; Chen, L; Cui, Y; He, M; Huang, X; Huo, Y; Li, J; Li, Y; Qin, X; Tang, G; Wang, B; Wu, H; Xu, X; Yin, D; Zhang, Y1
Ge, S; Hong, XN; Lu, SS; Shi, HB; Su, CQ; Xie, J1
Chen, Z; Dong, Y; Kang, Y; Shao, L; Tian, Y; Wang, J; Wang, X; Wang, Z; Zhang, L; Zheng, C1
Guo, H; Hou, FF; Huo, Y; Li, J; Lin, T; Liu, C; Liu, L; Qin, X; Song, Y; Wang, B; Wang, C; Wang, X; Xu, X; Yu, Y; Zhang, H; Zhang, Y; Zhou, Z1
Bai, H; Duan, S; Li, X; Wang, Y; Xiao, J; Yuan, Q; Zhang, S1
Larsson, SC; Markus, HS; Traylor, M1
Cao, S; Fei, X; Luo, Z; Qin, B; Sui, X; Wang, F; Xin, Y; Xu, N; Yang, J; Yang, Z; Zhang, Y; Zhang, Z; Zhao, H; Zhao, X1
Chen, H; Hui, Z; Ma, J; Ma, M; Peng, X; Wang, C; Wen, Q; Wu, G; Xu, G; Xu, S; Zhang, C; Zhang, J; Zhang, M1
Bu, X; Chen, J; Geng, D; Guo, D; He, J; Ju, Z; Li, Q; Peng, H; Peng, Y; Wang, A; Xu, T; Zhang, Y; Zheng, X; Zhong, C; Zhu, Z1
Bi, J; Sun, Z; Wang, Y; Wei, Y; Xie, Z; Xu, S; Xu, Y; Zhou, X; Zhu, Z1
Chi, S; Dong, Q; Hou, XH; Liu, Y; Ma, YH; Shen, XN; Song, JH; Sun, FR; Tan, L; Xu, W; Yu, JT1
Alemdar, M; Selekler, HM1
Dai, D; Li, A; Liu, C; Liu, X; Qin, X; Sun, Y; Wang, B; Xing, H1
Cheng, M; Liang, X; Liu, H; Sai, N; Wang, M; Wang, X; Yang, L; Zhang, X1
Kalani, A; Kamat, PK; Tyagi, N; Tyagi, SC1
Fang, S; Wu, J; Zhou, C1
Bai, X; Feng, C; Hua, T; Huang, J; Liu, XY; Xu, Y1
Han, J; Li, L; Liu, N; Liu, X; Liu, Z; Lv, Y; Shi, M; Wang, B; Wang, L; Wu, S; Xia, F; Yang, F; Zhao, G1
Burdine, J; Case, A; Dahlberg, K; Grewal, RP; Paolini, S; Peddareddygari, LR; Sen, S1
Fekih-Mrissa, N; Gritli, N; Klai, S; Mansour, M; Mrad, M; Mrissa, R; Nsiri, B1
Bukowska, H; Chełstowski, K; Gorący, I; Kłoda, K; Mierzecki, A; Naruszewicz, M1
Gaigalaite, V; Gribauskas, P; Kalibatene, D; Ojeraitene, V; Ptasekas, J; Sabaliauskiene, Z1
Idicula, T; Naess, H; Nyland, H; Waje-Andreassen, U1
Fang, S; Wu, J; Zhou, C; Zhu, L1
Almeida, OP; Chen, C; Eikelboom, JW; Ford, AH; Gommans, J; Hankey, GJ; Lees, KR; Navarro, JC; Ranawaka, UK; Ricci, S; Schmidt, R; Uddin, W; van Bockxmeer, FM; Xavier, D; Yi, Q1
Chen, H; Liu, TG; Tu, WJ; Yang, DG; Zhao, SJ1
Ding, J; Fan, W; Ge, AY; Wang, X; Wu, XQ1
Barski, R; Luvai, A; Narayanan, D; Sharma, R1
Bronić, A; Coen Herak, D; Leniček Krleža, J; Mejaški-Bošnjak, V; Zadro, R; Ðuranović, V1
Chen, C; Eikelboom, JW; Gommans, J; Hankey, GJ; Rodgers, H; Yi, Q1
Aizawa, T; Funase, Y; Ouchi, K; Sato, Y; Yamauchi, K1
Chi, FL; Xie, TH; Zhang, C; Zhou, YH1
Li, YS1
Doubal, F; Marlborough, F; Wardlaw, J; Webb, DJ; Wiseman, S1
Fenger, M; Grarup, N; Hansen, T; Husemoen, LL; Jørgensen, T; Linneberg, A; Pedersen, O; Sandholt, CH; Skaaby, T; Thuesen, BH1
Guo, X; Han, X; Li, X; Liu, W; Liu, Y; Peng, Y; Sun, L; Tian, J; Zhang, R1
Beiser, A; Bookman, E; Chen, F; Chen, WM; Doheny, KF; Gogarten, SM; Hsu, FC; Jacques, P; Keene, KL; Liu, X; Nelson, S; Sale, MM; Selhub, J; Seshadri, S; Wang, L; Weinstein, G; Williams, SR; Wolf, PA; Worrall, BB; Yang, Q; Zilka, M1
Arshi, B; Markovic, D; Ovbiagele, B; Towfighi, A1
Li, X; Ma, JP; Wang, JZ; Wang, L; Wu, CJ; Xia, XS1
Ahmadi, KR; Cotlarciuc, I; Dichgans, M; Fornage, M; Hasan, N; Holliday, EG; Ikram, MA; Kittner, SJ; Malik, R; Markus, HS; Meschia, JF; Mitchell, BD; Paré, G; Psaty, BM; Rinne, PE; Rosand, J; Sharma, P; Uitterlinden, AG; van Meurs, JB; Worrall, BB1
Chen, Y; Feng, L; He, Y; Li, Y; Nie, Z1
Jeon, SB; Kang, DW; Kim, JS; Kwon, SU1
Khanduri, U; Kumar, J; Neogi, SS; Sharma, A; Thomas, M1
Liu, C; Lv, L; Sun, W; Tong, W; Xu, T; Zhao, L; Zhong, C; Zhou, M1
Huang, K; Shang, X; Teng, W; Wang, L; Wu, D1
Wang, M; Wang, YL; Xu, CH; Xu, YN; Zeng, R1
Fujioka, T; Fuse, A; Hagiwara, W; Imamura, T; Inoue, M; Kitazono, H; Kobayashi, M; Konno, S; Murata, M; Nakazora, H; Nomoto, N; Sasaki, M; Sugimoto, H1
Kopyta, I; Sarecka-Hujar, B; Zimny, M1
Chen, Y; Ding, C; Ge, J; Jia, X; Jiang, B; Qiu, E; Yao, C; Yao, G; Zhang, Y; Zhao, H1
Alam, SF; Ganguly, P1
Arshi, B; Markovic, D; Ovbiagele, B; Saposnik, G; Towfighi, A1
Hou, F; Li, Y; Qin, X; Tang, G; Wang, B; Wang, X; Xie, D; Xu, X; Yuan, H1
Cloonan, L; Fitzpatrick, KM; Furie, KL; Kanakis, AS; Rosand, J; Rost, NS1
Alam, MT; Kanpurwala, MA; Khan, MS; Sadiq, M1
Cao, Y; Chen, QY; Fang, Y; Li, H; Liu, N; Liu, YC; Ma, J1
Li, WG; Shi, JP; Tang, CZ; Wang, WS; Zhang, YL1
Eide, GE; Maroy, TH; Mazengia, KY; Naess, H; Thomassen, L; Vedeler, CA; Waje-Andreassen, U1
Chen, S; Chen, Z; Duan, S; Fan, R; Han, L; Hao, Y; Li, R; Liu, K; Liu, S; Liu, Y; Ma, J; Peng, X; Wang, C; Wu, Q; Zhang, L; Zhang, T; Zhao, J; Zhuo, R1
Chen, YG; Qu, Y; Sun, Y; Wu, HL; Yu, LM; Zhang, HL1
Chen, S; Chen, Z; Duan, S; Fan, R; Han, L; Hao, Y; Li, R; Liu, S; Liu, Y; Ma, J; Peng, X; Wang, C; Wu, Q; Zhang, L; Zhang, T; Zhao, J1
Holloway, S; Hsu, FC; Lu, W; Marceau, R; Sale, MM; Tzeng, JY; Williams, SR; Worrall, BB1
Guan, Y; Huo, YR; Ji, Y; Liu, S; Lu, H; Shi, Z; Wang, J; Yue, W; Zhang, M1
Fang, H; Gao, Y; Ji, Y; Li, Y; Shi, C; Song, B; Sun, S; Tao, Y; Wu, J; Xu, Y; Zhao, L1
Chen, S; Chen, Z; Han, L; Liu, S; Ma, J; Peng, X; Wang, C; Zhao, D1
Bu, X; Chen, Q; Kong, F; Liu, Y; Wang, G; Xu, J; Zhang, Y1
Huo, Y; Qin, X1
Fang, H; Gao, Y; Ji, Y; Qin, J; Song, B; Sun, S; Wei, S; Xu, Y; Zhang, R1
Hu, S; Li, W; Liu, L; Ren, L; Wang, Y; Zhang, R; Zhao, X1
Dalen, I; Kurz, M; Larsen, JP; Mathisen, SM1
Gao, X; Geng, D; He, J; Li, Q; Peng, H; Peng, Y; Wang, A; Wang, J; Xu, T; Zhang, D; Zhang, Y; Zhong, C1
Fu, Q; Han, B; Pang, H; Zong, Z1
Arnone, G; Coveri, M; Forti, P; Maioli, F; Pirazzoli, GL; Procaccianti, G; Zoli, M1
Huo, Y; Jiang, S; Li, J; Li, Z; Tang, G; Venners, SA; Wang, B; Wang, Y; Xu, X; Zhang, Y1
Fu, RL; Geng, HH; Jing, MJ; Qiu, DX; Wang, PX; Xu, TF; Zhang, HS; Zhang, Q; Zheng, LC1
Banecka-Majkutewicz, Z; Banecki, B; Gabig-Cimińska, M; Grabowski, M; Jakóbkiewicz-Banecka, J; Kadziński, L; Węgrzyn, A; Węgrzyn, G1
Cass, A; Gallagher, MP; Jardine, MJ; Kang, A; Kulshrestha, S; Navaneethan, SD; Nigwekar, SU; Perkovic, V; Strippoli, GF; Zoungas, S1
Chen, S; Chen, Y; Guo, X; Qian, H; Sun, G; Sun, Y; Zhang, N1
Jiang, T; Ou, Z; Shi, JQ; Tian, YY; Wang, BR; Zhang, YD; Zhao, HD; Zhou, JS1
Beiser, AS; Benjamin, EJ; Kase, CS; Preis, SR; Romero, JR; Seshadri, S; Shoamanesh, A; Vasan, RS; Wolf, PA1
Luo, X; Tang, Y; Wang, H; Wang, MH; Xie, MJ; Yao, ES1
Bickel, C; Blankenberg, S; Lackner, K; Lubos, E; Proust, C; Rupprecht, H; Schnabel, RB; Sinning, C; Tregouet, D; Westermann, D; Zengin, E1
Bravo-Soto, GA; Madrid, T1
Hao, Y; Liu, W; Liu, X; Xu, G; Ye, Z; Zhang, H; Zhang, J; Zhang, Z1
Almeida, BR; Brito, CJ; Córdova, C; Daros, AC; Ferreira, AP; Gomes, L; Machado-Silva, W; Moraes, CF; Nóbrega, OT; Paula, RS; Souza, VC1
Gui, Y; Niu, X; Wang, J; Yan, H; Yan, Z; Zhang, P1
Gu, L; He, W; Li, G; Liu, D; Lu, M; Sun, Z1
Cao, LL; Li, Y; Liu, L; Qi, QD1
Cheng, QZ; Dong, XF; Guo, QZ; Kong, FZ; Luo, WF; Shen, AR; Wu, DF; Wu, GH1
Chen, J; Li, G; Lu, J; Peng, L; Shao, Y; Wang, Y; Xie, H; Xu, Z; Yuan, D; Zhang, C1
Coen Herak, D; Djuranovic, V; Horvat, I; Lenicek Krleza, J; Radic Antolic, M; Zadro, R; Zrinski Topic, R1
Edel, AL; Ganguly, PK; Maddaford, TG; O, K; Pierce, GN; Smeda, JS1
Claessen, BE; Clappers, N; Jansen, JB; Laheij, RJ; Peters, WH; van Oijen, MG; van Schaik, A; Verheugt, FW1
Adeyomoye, AA; Awosanya, GO; Danesi, MA; Okubadejo, NU; Oladipo, OO1
Allen, CL; Bayraktutan, U1
Collinson, P; Crossley, C; Kalra, L; Khan, U; Markus, HS; Rudd, A; Wolfe, CD1
Alam, MM; Ghani, U; Mohammad, AA; Schwindt, B; Shuaib, A; Shuaib, U; Todd, KG; Wang, C1
Arnolda, LF; Eikelboom, J; Green, DJ; Hankey, GJ; Jamrozik, K; Potter, K1
Bühler, R; Mattle, HP1
Dias, B; Munoz, C; Ozdemir, AO; Spence, JD; Tamayo, A1
Angelova, EA; Atanassova, PA; Chalakova, NT; Dimitrov, BD1
Lavie, CJ; Milani, RV1
Akar, N; Deda, G; Tras, ST1
Chin-Dusting, J; De Silva, DA; Kingwell, B; Koh, TH; Moe, KT; Wong, MC; Wong, P; Woon, FP1
Hamed, SA1
Anan, F; Eshima, N; Masaki, T; Nagano, S; Oribe, M; Saikawa, T; Tatsukawa, H; Yoshimatsu, H1
Jeong, DS; Kim, JS; Kim, YI; Lee, KS; Lee, SB; Lee, SJ; Ryu, SY; Song, IU1
Jax, T; Lauer, T1
Lorenzl, S1
Campbell, S; Greenberg, SM; Hyman, BT; Irizarry, MC; Raj, S; Stampfer, M; Viswanathan, A1
Baumgartner, RW; Benninger, DH; Georgiadis, D; Herrmann, FR; Kretschmer, R; Sarikaya, H; Schiller, A1
Bansal, V; Kalita, J; Kumar, G; Misra, UK1
Arnolda, LF; Beer, C; Eikelboom, JW; Hankey, GJ; Lenzo, N; Potter, K1
Bleich, S; Degirmenci, U; Fischlein, T; Kornhuber, J; Richter-Schmidinger, T; Weih, M; Zoll, A1
Lonn, E; McQueen, M; Ray, JG; Saposnik, G; Sheridan, P1
Liu, LS; Rao, KQ; Wang, YJ1
Fan, DS; Gao, XH; Liu, N; Qiao, SD; Zhou, JW1
Coskun, O; Inan, L; Kara, N; Saydam, G; Senes, M; Yucel, D1
Arora, S; Bhattacharjee, J; Dhamija, RK; Gaba, P; Kaintura, A; Kumar, M1
Chen, MF; Dahhou, M; Dassa, C; Evans, R; Genest, J; Goulet, L; Kahn, SR; Kramer, MS; Lydon, J; McNamara, H; Platt, RW; Rozen, R; Séguin, L1
Colla, M; Endres, M; Kronenberg, G1
Kidd, PM1
Chang, HM; Chen, CP; Eikelboom, JW; Hankey, GJ; Kasiman, K; Lee, JH; Lee, SP; Lim, JP; Wong, MC1
Kessels, F; Knottnerus, IL; Lodder, J; Ten Cate, H; van Oostenbrugge, RJ1
Chang, YY; Lai, SL; Lan, MY; Liu, JS; Su, CS; Tseng, YL1
Aridon, P; D'Amelio, M; Gueli, MC; Lupo, I; Mangiapane, P; Ragonese, P; Saia, V; Salemi, G1
Chen, J; Hui, R; Liao, Y; Ma, A; Qin, Q; Sun, K; Wang, D; Wang, Y; Zhang, W; Zhu, Z1
Chen, MF; Chien, KL; Hsu, HC; Lee, YT; Su, TC; Sun, Y1
Jiménez-Escrig, A; Martín, A; Sánchez-Moreno, C1
Carolei, A; Sacco, S1
Cho, YI; Jeong, SK; Lim, MH1
Chambers, ST; Elmslie, JL; Fink, JN; George, PM; Lever, M; Richards, AM; Scott, RS; Slow, S1
Fang, R; Liu, L; Ma, Y; Wang, Y; Zhang, W; Zhao, X1
Chen, SD; Ding, JQ; Fan, CN; Ma, JF; Song, YY; Xin, XY; Yang, GY1
Owusu, M; Pufulete, M; Thomas, J; Wiredu, E1
McNulty, H; Scott, JM; Strain, JJ; Ward, M; Wilson, CP1
Linnebank, M; Moskau, S; Semmler, A; Stoffel-Wagner, B1
Bastounis, E; Giaginis, K; Katsargyris, A; Klonaris, C; Theocharis, SE; Tsiodras, S1
Liebeskind, DS; Ovbiagele, B; Pineda, S; Saver, JL1
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Liao, JK; Wang, D; Yan, J1
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Badner, NH; Beattie, WS1
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Kalita, J; Misra, UK; Mittal, B; Somarajan, BI1
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Goldstein, LB2
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Ali, JM; Mejia Mohamed, EH; Mohamed, Z; Tan, KS1
Hong, SH; Kim, NK; Kim, OJ; Kim, TG; Min, KT; Oh, D; Oh, SH1
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Chen, M; Chen, Z; Jiang, Y; Lian, X; Liu, X; Wang, Q; Wang, W; Wu, B; Xu, G; Ye, X; Yue, X; Zhou, Z1
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Nugent, DJ; Rook, JL; Young, G1
Rafflenbeul, W1
Egido, JA1
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Chan, JB; Chen, CP; Eikelboom, JW; Hankey, GJ; Ho, GY; Tan, SL; Wong, CR1
Fan, D; Fu, Y; Shen, Y; Wang, H; Zhang, H; Zhang, J1
Furie, KL; Kelly, PJ1
Berry, RJ; Botto, LD; Erickson, JD; Friedman, JM; Johansen, H; Sambell, C; Yang, Q1
Adamtziki, E; Aronis, S; Kapsimali, Z; Komitopoulou, A; Pergantou, H; Platokouki, H1
Cook, S; Hess, OM1
Kajikawa, H; Kohriyama, T; Matsumoto, M; Mimori, Y; Naka, H; Nomura, E; Takahashi, T; Wakabayashi, S1
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Bukowska, H; Chelstowski, K; Honczarenko, K; Jastrzebska, M; Naruszewicz, M; Torbus-Lisiecka, B1

Reviews

93 review(s) available for homocysteine and Stroke

ArticleYear
Association between homocysteine levels in acute stroke and poststroke depression: A systematic review and meta-analysis.
    Brain and behavior, 2022, Volume: 12, Issue:6

    Topics: Depression; Homocysteine; Humans; Ischemic Stroke; Risk Factors; Stroke

2022
Problem in the Recent American Heart Association Guideline on Secondary Stroke Prevention: B Vitamins to Lower Homocysteine Do Prevent Stroke.
    Stroke, 2022, Volume: 53, Issue:8

    Topics: American Heart Association; Folic Acid; Homocysteine; Humans; Stroke; Vitamin B 12; Vitamin B Complex

2022
Risk factors and predictors for venous thromboembolism in people with ischemic stroke: A systematic review.
    Journal of thrombosis and haemostasis : JTH, 2022, Volume: 20, Issue:10

    Topics: Anticoagulants; Biomarkers; C-Reactive Protein; Homocysteine; Humans; Ischemic Stroke; Pulmonary Embolism; Risk Factors; Stroke; Venous Thromboembolism

2022
Homocysteine is associated with higher risks of ischemic stroke: A systematic review and meta-analysis.
    PloS one, 2022, Volume: 17, Issue:10

    Topics: Homocysteine; Humans; Ischemic Stroke; Prospective Studies; Risk Factors; Stroke

2022
Aberrant DNA methylation and miRNAs in coronary artery diseases and stroke: a systematic review.
    Briefings in functional genomics, 2020, 07-29, Volume: 19, Issue:4

    Topics: Cardiovascular Diseases; Coronary Artery Disease; Databases, Factual; Databases, Genetic; DNA Methylation; Genome-Wide Association Study; Homocysteine; Humans; Lipid Metabolism; MicroRNAs; Nitric Oxide; Stroke

2020
The association between homocysteine and ischemic stroke subtypes in Chinese: A meta-analysis.
    Medicine, 2020, Volume: 99, Issue:12

    Topics: Atherosclerosis; Brain Ischemia; China; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke

2020
Dietary Intake of Homocysteine Metabolism-Related B-Vitamins and the Risk of Stroke: A Dose-Response Meta-Analysis of Prospective Studies.
    Advances in nutrition (Bethesda, Md.), 2020, 11-16, Volume: 11, Issue:6

    Topics: Adult; Aged; China; Eating; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Nutrition Surveys; Prospective Studies; Risk Factors; Stroke; Vitamins

2020
Stroke Prevention in Older Adults: Recent Advances.
    Stroke, 2020, Volume: 51, Issue:12

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Atrial Fibrillation; Carotid Stenosis; Dementia; Diet; Diet, Vegetarian; Endarterectomy, Carotid; Ezetimibe; Factor Xa Inhibitors; Gastrointestinal Microbiome; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Patient Care Planning; Patient Selection; Platelet Aggregation Inhibitors; Renal Insufficiency; Stents; Stroke; Vascular Stiffness; Vitamin B Complex

2020
Reducing the Risk of Stroke in Patients with Impaired Renal Function: Nutritional Issues.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2021, Volume: 30, Issue:9

    Topics: Bacteria; Biomarkers; Comorbidity; Diet; Dietary Supplements; Gastrointestinal Microbiome; Homocysteine; Humans; Kidney; Nutritional Status; Protective Factors; Renal Insufficiency; Risk Assessment; Risk Factors; Stroke; Treatment Outcome; Uremia; Vitamin B 12; Vitamin B 12 Deficiency

2021
Homocysteine - from disease biomarker to disease prevention.
    Journal of internal medicine, 2021, Volume: 290, Issue:4

    Topics: Adult; Aged; Biomarkers; Child; Cognitive Dysfunction; Homocysteine; Humans; Macular Degeneration; Neural Tube Defects; Stroke; Vitamin B Complex

2021
The role of B vitamins in stroke prevention.
    Critical reviews in food science and nutrition, 2022, Volume: 62, Issue:20

    Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B 12; Vitamin B Complex

2022
Association of Homocysteine Level with Adverse Outcomes in Patients with Acute Ischemic Stroke: A Meta-Analysis.
    Current medicinal chemistry, 2021, Volume: 28, Issue:36

    Topics: Brain Ischemia; Homocysteine; Humans; Ischemic Stroke; Prognosis; Stroke

2021
Nutrition in Stroke Prevention.
    Seminars in neurology, 2017, Volume: 37, Issue:3

    Topics: Diet, Mediterranean; Gastrointestinal Microbiome; Homocysteine; Humans; Kidney Diseases; Stroke; Vitamin B 12 Deficiency

2017
Homocysteine in non-valvular atrial fibrillation: Role and clinical implications.
    Clinica chimica acta; international journal of clinical chemistry, 2017, Volume: 475

    Topics: Adult; Age Factors; Aged; Atrial Fibrillation; Biomarkers; Female; Heart Atria; Homocysteine; Humans; Male; Middle Aged; Oxidative Stress; Risk Factors; Sex Factors; Stroke; Thromboembolism

2017
Plasma homocysteine concentrations and risk of intracerebral hemorrhage: a systematic review and meta-analysis.
    Scientific reports, 2018, 02-07, Volume: 8, Issue:1

    Topics: Asian People; Cerebral Hemorrhage; Homocysteine; Humans; Race Factors; Risk Factors; Stroke; White People

2018
The current status of homocysteine as a risk factor for cardiovascular disease: a mini review.
    Expert review of cardiovascular therapy, 2018, Volume: 16, Issue:8

    Topics: Atherosclerosis; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex

2018
Synergy of homocysteine, microRNA, and epigenetics: a novel therapeutic approach for stroke.
    Molecular neurobiology, 2013, Volume: 48, Issue:1

    Topics: Animals; Epigenesis, Genetic; Homocysteine; Humans; Hyperhomocysteinemia; MicroRNAs; RNA Editing; Stroke

2013
Effect of B vitamins and lowering homocysteine on cognitive impairment in patients with previous stroke or transient ischemic attack: a prespecified secondary analysis of a randomized, placebo-controlled trial and meta-analysis.
    Stroke, 2013, Volume: 44, Issue:8

    Topics: Aged; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Ischemic Attack, Transient; Male; Middle Aged; Placebos; Recurrence; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B Complex

2013
Effect of B-vitamin supplementation on stroke: a meta-analysis of randomized controlled trials.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Dietary Supplements; Homocysteine; Humans; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex

2013
Blood markers of coagulation, fibrinolysis, endothelial dysfunction and inflammation in lacunar stroke versus non-lacunar stroke and non-stroke: systematic review and meta-analysis.
    Cerebrovascular diseases (Basel, Switzerland), 2014, Volume: 37, Issue:1

    Topics: Biomarkers; Blood Coagulation; Blood Proteins; Brain Ischemia; Cell Adhesion Molecules; Cytokines; Endothelium, Vascular; Fibrinolysis; Homocysteine; Humans; Inflammation; Stroke; Stroke, Lacunar

2014
Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.
    PLoS genetics, 2014, Volume: 10, Issue:3

    Topics: Aldehyde Dehydrogenase; Carbon; Folic Acid; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Methionine; Oxidoreductases Acting on CH-NH Group Donors; Stroke; Vitamin B 12

2014
Homocysteine level and risk of different stroke types: a meta-analysis of prospective observational studies.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:11

    Topics: Databases, Factual; Homocysteine; Humans; Observational Studies as Topic; Recurrence; Risk Factors; Stroke

2014
The effect of folate fortification on folic acid-based homocysteine-lowering intervention and stroke risk: a meta-analysis.
    Public health nutrition, 2015, Volume: 18, Issue:8

    Topics: Databases, Factual; Folic Acid; Food, Fortified; Homocysteine; Humans; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B 12

2015
The role of biochemical risk factors in the etiology of AIS in children and adults.
    The International journal of neuroscience, 2015, Volume: 125, Issue:12

    Topics: Adult; Animals; Blood Proteins; Brain Ischemia; Child; Cholesterol; Homocysteine; Humans; Risk Factors; Stroke

2015
Role of homocysteine in the development of cardiovascular disease.
    Nutrition journal, 2015, Jan-10, Volume: 14

    Topics: Brain; Cardiovascular Diseases; Catecholamines; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Hypothalamus; Placebos; Stroke

2015
Interventions for lowering plasma homocysteine levels in dialysis patients.
    The Cochrane database of systematic reviews, 2016, May-31, Issue:5

    Topics: Aged; Cardiovascular Diseases; Cause of Death; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Renal Dialysis; Stroke; Venous Thrombosis; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2016
Homocysteine lowering for stroke prevention: Unravelling the complexity of the evidence.
    International journal of stroke : official journal of the International Stroke Society, 2016, Volume: 11, Issue:7

    Topics: Clinical Trials as Topic; Homocysteine; Humans; Stroke

2016
Is folic acid supplementation useful for chronic kidney disease?
    Medwave, 2016, Nov-07, Volume: 16, Issue:Suppl5

    Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Humans; Myocardial Infarction; Renal Insufficiency, Chronic; Risk Factors; Stroke

2016
Risk factors for ischaemic stroke.
    International journal of stroke : official journal of the International Stroke Society, 2008, Volume: 3, Issue:2

    Topics: Aging; Atherosclerosis; Atrial Fibrillation; Brain Ischemia; Heart Failure; Homocysteine; Humans; Hypertension; Leukocyte Count; Risk Factors; Stroke; Waist-Hip Ratio

2008
The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis.
    BMC cardiovascular disorders, 2008, Sep-20, Volume: 8

    Topics: Aged; Carotid Arteries; Dietary Supplements; Double-Blind Method; Down-Regulation; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Regional Blood Flow; Stroke; Time Factors; Treatment Outcome; Tunica Intima; Tunica Media; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2008
Hematological diseases and stroke.
    Handbook of clinical neurology, 2009, Volume: 93

    Topics: Blood Coagulation; Hematologic Diseases; Homocysteine; Humans; Stroke

2009
The vascular risk associations with migraine: relation to migraine susceptibility and progression.
    Atherosclerosis, 2009, Volume: 205, Issue:1

    Topics: Blood Pressure; Body Mass Index; Body Weight; C-Reactive Protein; Comorbidity; Disease Susceptibility; Homocysteine; Humans; Inflammation; Interleukins; Migraine Disorders; Risk; Risk Factors; Stroke; Tumor Necrosis Factor-alpha; Vascular Diseases

2009
Folic acid, neurodegenerative and neuropsychiatric disease.
    Current molecular medicine, 2009, Volume: 9, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Brain; Clinical Trials as Topic; Dementia, Vascular; Depression; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Molecular Structure; Neurodegenerative Diseases; Neuronal Plasticity; Stroke; Vitamin B Complex

2009
Integrated brain restoration after ischemic stroke--medical management, risk factors, nutrients, and other interventions for managing inflammation and enhancing brain plasticity.
    Alternative medicine review : a journal of clinical therapeutic, 2009, Volume: 14, Issue:1

    Topics: Anticoagulants; Brain; Brain Ischemia; Homocysteine; Humans; Hyperbaric Oxygenation; Inflammation; Intercellular Signaling Peptides and Proteins; Neuronal Plasticity; Neuroprotective Agents; Platelet Aggregation Inhibitors; Recovery of Function; Risk Factors; Secondary Prevention; Stem Cell Transplantation; Stroke; Thrombolytic Therapy; Vasodilator Agents

2009
Endothelial dysfunction in lacunar stroke: a systematic review.
    Cerebrovascular diseases (Basel, Switzerland), 2009, Volume: 27, Issue:5

    Topics: Brain Infarction; Endothelium, Vascular; Hemostasis; Homocysteine; Humans; Stroke; Vasodilation

2009
Stroke: roles of B vitamins, homocysteine and antioxidants.
    Nutrition research reviews, 2009, Volume: 22, Issue:1

    Topics: Antioxidants; Avitaminosis; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vegetables; Vitamin B Complex; Vitamins

2009
Gene polymorphisms and risk of adult early-onset ischemic stroke: A meta-analysis.
    Thrombosis research, 2009, Volume: 124, Issue:5

    Topics: Adolescent; Adult; Apolipoproteins E; Case-Control Studies; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Lipid Metabolism; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Stroke; Young Adult

2009
Postgraduate Symposium: The MTHFR C677T polymorphism, B-vitamins and blood pressure.
    The Proceedings of the Nutrition Society, 2010, Volume: 69, Issue:1

    Topics: Blood Pressure; Clinical Trials as Topic; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Hypertension; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Riboflavin; Risk Factors; Stroke; Vitamin B Complex

2010
Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: a meta-analysis.
    Stroke, 2010, Volume: 41, Issue:6

    Topics: Female; Folic Acid; Homocysteine; Humans; Male; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2010
The complex mutual connection between stroke and bone health.
    Archives of biochemistry and biophysics, 2010, Nov-01, Volume: 503, Issue:1

    Topics: Animals; Bone and Bones; Bone Diseases; Health; Homocysteine; Humans; Stroke; Vitamin D

2010
Combined analyses and extended follow-up of two randomized controlled homocysteine-lowering B-vitamin trials.
    Journal of internal medicine, 2010, Volume: 268, Issue:4

    Topics: Capsules; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Patient Compliance; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2010
Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals.
    Archives of internal medicine, 2010, Oct-11, Volume: 170, Issue:18

    Topics: Biomarkers; Cardiovascular Diseases; Cause of Death; Confidence Intervals; Dietary Supplements; Folic Acid; Homocysteine; Humans; Incidence; Neoplasms; Randomized Controlled Trials as Topic; Stroke; Treatment Failure; Vitamin B Complex

2010
Homocysteine and vitamin therapy in stroke prevention and treatment: a review.
    Acta biochimica Polonica, 2010, Volume: 57, Issue:4

    Topics: Homocysteine; Humans; Risk Factors; Stroke; Vitamin B Complex; Vitamins

2010
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials.
    Lancet (London, England), 2011, Aug-13, Volume: 378, Issue:9791

    Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex

2011
C(1) metabolism and CVD outcomes in older adults.
    The Proceedings of the Nutrition Society, 2012, Volume: 71, Issue:2

    Topics: Blood Pressure; Carbon; Cardiovascular Diseases; Folic Acid; Genetic Predisposition to Disease; Genotype; Heart Diseases; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Riboflavin; Stroke; Vitamin B Complex

2012
Paraoxonase 1 and homocysteine metabolism.
    Amino acids, 2012, Volume: 43, Issue:4

    Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Atherosclerosis; Coronary Artery Disease; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipoproteins, HDL; Mice; Oxidative Stress; Stroke

2012
Meta-analysis of B vitamin supplementation on plasma homocysteine, cardiovascular and all-cause mortality.
    Clinical nutrition (Edinburgh, Scotland), 2012, Volume: 31, Issue:4

    Topics: Coronary Disease; Databases, Factual; Dietary Supplements; Homocysteine; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex

2012
[Kynurenic acid--a new tool in the treatment of hiperhomocysteinemia and its consequences?].
    Postepy higieny i medycyny doswiadczalnej (Online), 2012, Jun-22, Volume: 66

    Topics: Atherosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Kynurenic Acid; Stroke; Tissue Distribution

2012
Homocysteine, heat shock proteins, genistein and vitamins in ischemic stroke--pathogenic and therapeutic implications.
    Acta biochimica Polonica, 2012, Volume: 59, Issue:4

    Topics: Dietary Supplements; Genistein; Heat-Shock Proteins; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Vitamins

2012
Homocysteine, MTHFR 677C-->T polymorphism, and risk of ischemic stroke: results of a meta-analysis.
    Neurology, 2002, Aug-27, Volume: 59, Issue:4

    Topics: Brain Ischemia; Case-Control Studies; Cohort Studies; Comorbidity; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prevalence; Prospective Studies; Retrospective Studies; Risk Assessment; Stroke

2002
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
    Trends in neurosciences, 2003, Volume: 26, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke

2003
Homocysteine, renal function, and risk of cardiovascular disease.
    Kidney international. Supplement, 2003, Issue:84

    Topics: Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Prospective Studies; Risk Factors; Stroke

2003
Nutritional and metabolic aspects of stroke prevention.
    Advances in neurology, 2003, Volume: 92

    Topics: Animals; Antioxidants; Cholesterol, Dietary; Diet; Dietary Fats; Homocysteine; Humans; Stroke; Vitamins

2003
[Homocysteine and neuropsychiatric disorders].
    Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2004, Volume: 26, Issue:1

    Topics: Alzheimer Disease; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mental Disorders; Parkinson Disease; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6

2004
Homocysteine, B-vitamin supplementation, and stroke prevention: from observational to interventional trials.
    The Lancet. Neurology, 2004, Volume: 3, Issue:8

    Topics: Animals; Clinical Trials as Topic; Dietary Supplements; Homocysteine; Humans; Meta-Analysis as Topic; Stroke; Treatment Outcome; Vitamin B Complex

2004
Novel therapies for the prevention of stroke.
    Expert opinion on investigational drugs, 2004, Volume: 13, Issue:12

    Topics: Anti-Inflammatory Agents; Anticoagulants; Antihypertensive Agents; Fish Oils; Homocysteine; Humans; Preventive Medicine; Stroke; Treatment Outcome

2004
Secondary prevention of recurrent stroke.
    Stroke, 2005, Volume: 36, Issue:2

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Diabetes Complications; Endarterectomy; Endarterectomy, Carotid; Fibrinolytic Agents; Homocysteine; Humans; Platelet Aggregation Inhibitors; Risk; Risk Factors; Secondary Prevention; Stents; Stroke; Ticlopidine; Vitamin B Complex

2005
Homocysteine-lowering trials for prevention of heart disease and stroke.
    Seminars in vascular medicine, 2005, Volume: 5, Issue:2

    Topics: Biomarkers; Clinical Trials as Topic; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Treatment Outcome; Vitamin B Complex

2005
Homocysteine and coronary heart disease.
    Seminars in vascular medicine, 2002, Volume: 2, Issue:4

    Topics: Adult; Child; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B Complex; Vitamins

2002
[Homocysteine--risk factor or risk indicator?].
    MMW Fortschritte der Medizin, 2005, Nov-03, Volume: 147, Issue:44

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Child; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex

2005
Benefits of modifying the predictive factors of stroke recurrence.
    Cerebrovascular diseases (Basel, Switzerland), 2005, Volume: 20 Suppl 2

    Topics: Age Factors; Aged; Biomarkers; Dementia; Hemostasis; Homocysteine; Humans; Inflammation; Risk Factors; Secondary Prevention; Stroke

2005
Homocysteine-lowering trials for prevention of cardiovascular events: a review of the design and power of the large randomized trials.
    American heart journal, 2006, Volume: 151, Issue:2

    Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Homocystinuria; Humans; Kidney Diseases; Myocardial Infarction; Randomized Controlled Trials as Topic; Stroke; Vitamin B Complex

2006
Homocyst(e)ine and stroke.
    Seminars in neurology, 2006, Volume: 26, Issue:1

    Topics: Clinical Trials as Topic; Dietary Supplements; Homocysteine; Humans; Risk; Stroke; Vitamins

2006
Homocysteine and B vitamins.
    Handbook of experimental pharmacology, 2005, Issue:170

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Vitamin B Complex

2005
Inflammation, atherosclerosis, and stroke.
    The neurologist, 2006, Volume: 12, Issue:3

    Topics: Antigens, CD; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Coronary Artery Disease; Cytokines; Diffusion Magnetic Resonance Imaging; Homocysteine; Humans; Inflammation; Internal Capsule; Intracranial Arteriosclerosis; Risk Factors; Stroke

2006
The many facets of hyperhomocysteinemia: studies from the Framingham cohorts.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Massachusetts; Middle Aged; Risk Factors; Stroke; Vascular Diseases; Vitamin B 12; Vitamin B 6

2006
[Homocysteine].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 5

    Topics: Animals; Arteriosclerosis; Biomarkers; Homocysteine; Humans; Kidney Failure, Chronic; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Ischemia; Oxidative Stress; Polymorphism, Genetic; Risk Factors; Stroke; Thrombosis

2006
Is plasma homocysteine a modifiable risk factor for stroke?
    Nature clinical practice. Neurology, 2006, Volume: 2, Issue:1

    Topics: Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Thrombosis; Vitamins

2006
[Coagulation disorders and stroke].
    Hamostaseologie, 2006, Volume: 26, Issue:4

    Topics: Antibodies, Antiphospholipid; Blood Coagulation Disorders; Erythrocyte Count; Homocysteine; Humans; Intracranial Thrombosis; Methylenetetrahydrofolate Reductase (NADPH2); Platelet Count; Polymorphism, Genetic; Protein C; Prothrombin Time; Stroke

2006
Homocysteine and cerebral ischemia: pathogenic and therapeutical implications.
    Current medicinal chemistry, 2007, Volume: 14, Issue:3

    Topics: Brain Ischemia; Diet; Homocysteine; Humans; Life Style; Methylenetetrahydrofolate Reductase (NADPH2); Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vascular Diseases; Vitamins

2007
[The role of homocysteine thiolactone in some of human diseases].
    Postepy biochemii, 2006, Volume: 52, Issue:4

    Topics: Animals; Aryldialkylphosphatase; Atherosclerosis; Biomarkers; Fibrinogen; Folic Acid; Homocysteine; Humans; Lipoproteins, HDL; Rabbits; Stroke; Vitamin B 12; Vitamin B 6

2006
The homocysteine hypothesis of depression.
    The American journal of psychiatry, 2007, Volume: 164, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Child; Comorbidity; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mutation; Neurotransmitter Agents; Stroke; Vitamin B 12; Vitamin B 6

2007
Efficacy of folic acid supplementation in stroke prevention: a meta-analysis.
    Lancet (London, England), 2007, Jun-02, Volume: 369, Issue:9576

    Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk; Stroke; Vitamin B Complex

2007
[Nutritional medicine 2007].
    Deutsche medizinische Wochenschrift (1946), 2007, Jun-22, Volume: 132, Issue:25-26

    Topics: Cardiovascular Diseases; Diet; Evidence-Based Medicine; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Practice Guidelines as Topic; Primary Prevention; Risk Assessment; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2007
Homocysteine-lowering therapy: a role in stroke prevention?
    The Lancet. Neurology, 2007, Volume: 6, Issue:9

    Topics: Animals; Clinical Trials as Topic; Homocysteine; Humans; Myocardial Infarction; Risk; Stroke; Vitamin B 12; Vitamin B 6

2007
Homocysteine and cerebral stroke in developing countries.
    Current medicinal chemistry, 2007, Volume: 14, Issue:22

    Topics: Developing Countries; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Nutritional Status; Stroke; Vitamin B 12

2007
Homocysteine in the prevention of ischemic heart disease, stroke and venous thromboembolism: therapeutic target or just another distraction?
    Current opinion in hematology, 2007, Volume: 14, Issue:5

    Topics: Atherosclerosis; Homocysteine; Humans; Meta-Analysis as Topic; Metabolism, Inborn Errors; Myocardial Ischemia; Randomized Controlled Trials as Topic; Stroke; Thromboembolism

2007
Vitamins and stroke: the homocysteine hypothesis still in doubt.
    The neurologist, 2008, Volume: 14, Issue:1

    Topics: Cardiovascular Diseases; Clinical Trials as Topic; Dietary Supplements; Folic Acid; Homocysteine; Humans; Intracranial Arteriosclerosis; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B 6

2008
Homocysteine and risk of stroke.
    Journal of cardiovascular risk, 1999, Volume: 6, Issue:4

    Topics: Arteriosclerosis; Carotid Stenosis; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Prevalence; Risk Factors; Stroke

1999
Stroke prevention.
    Physical medicine and rehabilitation clinics of North America, 1999, Volume: 10, Issue:4

    Topics: Cardiovascular Diseases; Fibrinolytic Agents; Homocysteine; Humans; Hypercholesterolemia; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Risk Factors; Stroke

1999
Can lowering homocysteine levels reduce the incidence of stroke?
    Journal of clinical pharmacy and therapeutics, 1999, Volume: 24, Issue:5

    Topics: Animals; Arteriosclerosis; Homocysteine; Humans; Incidence; Risk Factors; Stroke

1999
Lipoprotein (a) and stroke.
    Journal of clinical pathology, 2000, Volume: 53, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Cross-Sectional Studies; Female; Fibrinogen; Homocysteine; Humans; Lipids; Lipoprotein(a); Male; Middle Aged; Prospective Studies; Risk Factors; Stroke

2000
Occlusive vascular diseases in oral contraceptive users. Epidemiology, pathology and mechanisms.
    Drugs, 2000, Volume: 60, Issue:4

    Topics: Adult; Carbohydrate Metabolism; Cardiovascular Diseases; Case-Control Studies; Contraceptives, Oral, Synthetic; Female; Homocysteine; Humans; Incidence; Lipid Metabolism; Myocardial Infarction; Risk Factors; Stroke; Structure-Activity Relationship; Thromboembolism

2000
Novel risk factors for stroke: homocysteine, inflammation, and infection.
    Current atherosclerosis reports, 2000, Volume: 2, Issue:2

    Topics: Homocysteine; Humans; Infections; Inflammation; Risk Factors; Stroke

2000
Homocysteine and stroke.
    Current opinion in neurology, 2001, Volume: 14, Issue:1

    Topics: Brain Ischemia; Homocysteine; Humans; Stroke

2001
Dairy food consumption, blood pressure and stroke.
    The Journal of nutrition, 2001, Volume: 131, Issue:7

    Topics: Blood Pressure; Calcium, Dietary; Dairy Products; Homocysteine; Humans; Hypertension; Insulin Resistance; Lipid Peroxidation; Magnesium; Potassium, Dietary; Prospective Studies; Risk Factors; Stroke

2001
Homocysteine levels in patients with stroke: clinical relevance and therapeutic implications.
    CNS drugs, 2001, Volume: 15, Issue:6

    Topics: Animals; Biomarkers; Homocysteine; Humans; Stroke; Treatment Outcome

2001
Nutrition and cognitive impairment in the elderly.
    The British journal of nutrition, 2001, Volume: 86, Issue:3

    Topics: Aged; Aging; Alzheimer Disease; Antioxidants; Avitaminosis; Dementia; Dementia, Vascular; Dietary Supplements; Educational Status; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hypertension; Life Style; Nutritional Physiological Phenomena; Nutritional Status; Risk Factors; Stroke; Vitamin B 12 Deficiency

2001
[Hereditary metabolic causes of stroke and pseudo-stroke in adulthood].
    La Revue de medecine interne, 2001, Volume: 22 Suppl 3

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Fabry Disease; Homocysteine; Humans; Metabolism, Inborn Errors; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Stroke

2001
Homocysteine and atherothrombosis.
    Lipids, 2001, Volume: 36 Suppl

    Topics: Arteriosclerosis; Diet; Homocysteine; Humans; Hyperhomocysteinemia; Myocardial Ischemia; Risk Factors; Stroke; Thrombosis

2001
The VITATOPS (Vitamins to Prevent Stroke) Trial: rationale and design of an international, large, simple, randomised trial of homocysteine-lowering multivitamin therapy in patients with recent transient ischaemic attack or stroke.
    Cerebrovascular diseases (Basel, Switzerland), 2002, Volume: 13, Issue:2

    Topics: Biomarkers; Brain; Disease Progression; Double-Blind Method; Follow-Up Studies; Homocysteine; Humans; Ischemic Attack, Transient; Magnetic Resonance Imaging; Risk Factors; Stroke; Time Factors; Treatment Outcome; Vitamins

2002
Is homocysteine a causal and treatable risk factor for vascular diseases of the brain (cognitive impairment and stroke)?
    Annals of neurology, 2002, Volume: 51, Issue:3

    Topics: Cognition Disorders; Homocysteine; Humans; Risk Factors; Stroke

2002
Folic acid and homocysteine in age-related disease.
    Ageing research reviews, 2002, Volume: 1, Issue:1

    Topics: Aged; Aging; Cardiovascular Diseases; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Mental Disorders; Neoplasms; Neurodegenerative Diseases; Stroke

2002

Trials

43 trial(s) available for homocysteine and Stroke

ArticleYear
Combined use of amlodipine and folic acid are significantly more efficacious than amlodipine alone in lowering plasma homocysteine and blood pressure among hypertensive patients with hyperhomocysteinemia and intolerance to ACEI: A multicenter, randomized,
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:8

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Stroke; Treatment Outcome

2023
Homocysteine Level Predicts Response to Dual Antiplatelet in Women With Minor Stroke or Transient Ischemic Attack: Subanalysis of the CHANCE Trial.
    Arteriosclerosis, thrombosis, and vascular biology, 2020, Volume: 40, Issue:3

    Topics: Aged; Aspirin; Biomarkers; China; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Risk Assessment; Risk Factors; Sex Factors; Stroke; Time Factors; Treatment Outcome

2020
Homocysteine and Stroke Risk: Modifying Effect of Methylenetetrahydrofolate Reductase C677T Polymorphism and Folic Acid Intervention.
    Stroke, 2017, Volume: 48, Issue:5

    Topics: Aged; Antihypertensive Agents; China; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Folic Acid; Follow-Up Studies; Genotype; Homocysteine; Humans; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Stroke; Treatment Outcome; Vitamin B Complex

2017
Association between percent decline in serum total homocysteine and risk of first stroke.
    Neurology, 2017, Nov-14, Volume: 89, Issue:20

    Topics: Aged; Antihypertensive Agents; China; Drug Therapy, Combination; Enalapril; Female; Folic Acid; Homocysteine; Humans; Hypertension; Male; Middle Aged; Risk; Stroke; Vitamin B Complex

2017
Elevated circulating homocysteine and high-sensitivity C-reactive protein jointly predicts post-stroke depression among Chinese patients with acute ischemic stroke.
    Clinica chimica acta; international journal of clinical chemistry, 2018, Volume: 479

    Topics: Acute Disease; Brain Ischemia; C-Reactive Protein; China; Depression; Female; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Stroke

2018
Platelet Count Affects Efficacy of Folic Acid in Preventing First Stroke.
    Journal of the American College of Cardiology, 2018, 05-15, Volume: 71, Issue:19

    Topics: Aged; China; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hypertension; Male; Middle Aged; Platelet Count; Stroke; Treatment Outcome; Vitamin B Complex

2018
Mecobalamin and early functional outcomes of ischemic stroke patients with H-type hypertension.
    Revista da Associacao Medica Brasileira (1992), 2018, Volume: 64, Issue:5

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Homocysteine; Humans; Hypertension; Male; Middle Aged; Prognosis; Stroke; Treatment Outcome; Vitamin B 12

2018
Effect of long-term low-dose folic acid supplementation on degree of total homocysteine-lowering: major effect modifiers.
    The British journal of nutrition, 2018, Volume: 120, Issue:10

    Topics: Aged; China; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Genotype; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Smoking; Stroke

2018
Plasma retinol and the risk of first stroke in hypertensive adults: a nested case-control study.
    The American journal of clinical nutrition, 2019, 02-01, Volume: 109, Issue:2

    Topics: Aged; Antihypertensive Agents; Brain Ischemia; Case-Control Studies; China; Double-Blind Method; Enalapril; Female; Folic Acid; Hemorrhage; Homocysteine; Humans; Hypertension; Male; Middle Aged; Odds Ratio; Primary Prevention; Risk Factors; Stroke; Vitamin A; Vitamin A Deficiency

2019
The China Stroke Secondary Prevention Trial (CSSPT) protocol: a double-blinded, randomized, controlled trial of combined folic acid and B vitamins for secondary prevention of stroke.
    International journal of stroke : official journal of the International Stroke Society, 2015, Volume: 10, Issue:2

    Topics: Adult; Aged; Brain Ischemia; China; Double-Blind Method; Folic Acid; Homocysteine; Humans; Intracranial Hemorrhage, Hypertensive; Middle Aged; Myocardial Infarction; Protective Agents; Research Design; Secondary Prevention; Stroke; Vitamin B 12; Vitamin B 6

2015
Homocysteine and metabolic risk factors in individuals with family history of premature ischemic stroke.
    Polskie Archiwum Medycyny Wewnetrznej, 2013, Volume: 123, Issue:6

    Topics: Adolescent; Adult; Apolipoprotein A-I; Apolipoproteins B; Biomarkers; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Female; Homocysteine; Humans; Male; Middle Aged; Primary Prevention; Risk Factors; Sex Characteristics; Stroke; Triglycerides; Young Adult

2013
Effect of B vitamins and lowering homocysteine on cognitive impairment in patients with previous stroke or transient ischemic attack: a prespecified secondary analysis of a randomized, placebo-controlled trial and meta-analysis.
    Stroke, 2013, Volume: 44, Issue:8

    Topics: Aged; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Ischemic Attack, Transient; Male; Middle Aged; Placebos; Recurrence; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B Complex

2013
The effect of homocysteine-lowering with B-vitamins on osteoporotic fractures in patients with cerebrovascular disease: substudy of VITATOPS, a randomised placebo-controlled trial.
    BMC geriatrics, 2013, Sep-03, Volume: 13

    Topics: Aged; Biomarkers; Cerebrovascular Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Osteoporotic Fractures; Prospective Studies; Stroke; Treatment Outcome; Vitamin B Complex

2013
Supplementation of folic acid and vitamin B₁₂ reduces plasma levels of asymmetric dimethylarginine in patients with acute ischemic stroke.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:9

    Topics: Aged; Arginine; Blood Chemical Analysis; Brain Ischemia; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Stroke; Time Factors; Treatment Outcome; Vitamin B 12

2014
Differential effect of B-vitamin therapy by antiplatelet use on risk of recurrent vascular events after stroke.
    Stroke, 2015, Volume: 46, Issue:3

    Topics: Age Factors; Aged; Data Interpretation, Statistical; Double-Blind Method; Female; Homocysteine; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Recurrence; Risk Factors; Stroke; Treatment Outcome; Vitamin B Complex

2015
Plasma Homocysteine and Prognosis of Acute Ischemic Stroke: a Gender-Specific Analysis From CATIS Randomized Clinical Trial.
    Molecular neurobiology, 2017, Volume: 54, Issue:3

    Topics: Aged; Antihypertensive Agents; Biomarkers; Brain Ischemia; China; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Prognosis; Prospective Studies; Sex Characteristics; Single-Blind Method; Stroke

2017
The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis.
    BMC cardiovascular disorders, 2008, Sep-20, Volume: 8

    Topics: Aged; Carotid Arteries; Dietary Supplements; Double-Blind Method; Down-Regulation; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Regional Blood Flow; Stroke; Time Factors; Treatment Outcome; Tunica Intima; Tunica Media; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2008
Plasma Abeta, homocysteine, and cognition: the Vitamin Intervention for Stroke Prevention (VISP) trial.
    Neurology, 2009, Jan-20, Volume: 72, Issue:3

    Topics: Aged; Amyloid beta-Peptides; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Down-Regulation; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Osmolar Concentration; Peptide Fragments; Pyridoxine; Stroke; Treatment Failure; Vitamin B 12; Vitamin B Complex; Vitamins

2009
Effect of long-term homocysteine reduction with B vitamins on arterial wall inflammation assessed by fluorodeoxyglucose positron emission tomography: a randomised double-blind, placebo-controlled trial.
    Cerebrovascular diseases (Basel, Switzerland), 2009, Volume: 27, Issue:3

    Topics: Aged; Aged, 80 and over; Aorta; Arteritis; Atherosclerosis; Brachial Artery; Carotid Arteries; Cross-Sectional Studies; Double-Blind Method; Drug Combinations; Female; Femoral Artery; Fluorodeoxyglucose F18; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Stroke; Time Factors; Treatment Outcome; Ultrasonography; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2009
Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trial.
    Stroke, 2009, Volume: 40, Issue:4

    Topics: Aged; Disability Evaluation; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins

2009
Ethnicity does not affect the homocysteine-lowering effect of B-vitamin therapy in Singaporean stroke patients.
    Stroke, 2009, Volume: 40, Issue:6

    Topics: Aged; China; Diet; Ethnicity; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; India; Malaysia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors; Singapore; Stroke; Vitamin B Complex

2009
Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine.
    Cardiovascular drugs and therapy, 2009, Volume: 23, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Betaine; Clofibric Acid; Cohort Studies; Diabetes Complications; Female; Homocysteine; Humans; Hypolipidemic Agents; Lipids; Male; S-Adenosylmethionine; Stroke

2009
Novel pro-atherogenic molecule coupling factor 6 is elevated in patients with stroke: a possible linkage to homocysteine.
    Annals of medicine, 2010, Volume: 42, Issue:1

    Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Japan; Male; Middle Aged; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation Coupling Factors; Stroke; Vitamin B 12; Vitamin B Complex

2010
Cortical and frontal atrophy are associated with cognitive impairment in age-related confluent white-matter lesion.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:1

    Topics: Aged; Aging; Atrophy; Cerebral Amyloid Angiopathy; Cerebral Cortex; Cognition Disorders; Double-Blind Method; Executive Function; Female; Frontal Lobe; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Predictive Value of Tests; Regression Analysis; Stroke

2011
Nitrous oxide and long-term morbidity and mortality in the ENIGMA trial.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:2

    Topics: Aged; Anesthetics, Inhalation; Biomarkers; Cause of Death; Chi-Square Distribution; Female; Follow-Up Studies; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Nitrous Oxide; Odds Ratio; Proportional Hazards Models; Risk Assessment; Risk Factors; Stroke; Surgical Procedures, Operative; Survival Rate; Time Factors; Treatment Outcome

2011
Utility of Framingham Coronary Heart Disease Risk Score for predicting cardiac risk after stroke.
    Stroke, 2012, Volume: 43, Issue:11

    Topics: Adult; Coronary Disease; Double-Blind Method; Female; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Risk Factors; Stroke; Vitamins

2012
Vitamin intervention for stroke prevention.
    Journal of the neurological sciences, 2002, Nov-15, Volume: 203-204

    Topics: Aged; Diet; Double-Blind Method; Electrocardiography; Endpoint Determination; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Recurrence; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6; Vitamins

2002
Homocysteine testing in patients with acute ischemic stroke.
    Neurology, 2002, Nov-26, Volume: 59, Issue:10

    Topics: Acute Disease; Age Factors; Aged; Analysis of Variance; Biomarkers; Diabetes Mellitus; Embolism; Female; Homocysteine; Humans; Hyperlipidemias; Logistic Models; Male; Middle Aged; Odds Ratio; Risk Factors; Stroke

2002
Measurement of carotid plaque and effect of vitamin therapy for total homocysteine.
    Clinical chemistry and laboratory medicine, 2003, Volume: 41, Issue:11

    Topics: Aged; Carotid Stenosis; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Imaging, Three-Dimensional; Reproducibility of Results; Stroke; Ultrasonography; Vitamin B 12; Vitamin B 6; Vitamins

2003
Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial.
    JAMA, 2004, Feb-04, Volume: 291, Issue:5

    Topics: Adult; Aged; Coronary Disease; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Recurrence; Risk; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B 6

2004
B-group vitamin supplementation mitigates oxidative damage after acute ischaemic stroke.
    Clinical science (London, England : 1979), 2004, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Antioxidants; C-Reactive Protein; Dietary Supplements; Female; Homocysteine; Humans; Male; Oxidative Stress; Stroke; Vitamin B Complex

2004
Homocysteine-lowering treatment with folic acid, cobalamin, and pyridoxine does not reduce blood markers of inflammation, endothelial dysfunction, or hypercoagulability in patients with previous transient ischemic attack or stroke: a randomized substudy o
    Stroke, 2005, Volume: 36, Issue:1

    Topics: Biomarkers; Blood Coagulation; Cardiovascular Diseases; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Inflammation; Ischemic Attack, Transient; Pyridoxine; Risk Factors; Stroke; Vitamin B 12; Vitamin B Complex

2005
Sustained homocysteine-lowering effect over time of folic acid-based multivitamin therapy in stroke patients despite increasing folate status in the population.
    Cerebrovascular diseases (Basel, Switzerland), 2005, Volume: 19, Issue:2

    Topics: Aged; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Hematinics; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Stroke; Time Factors; Vitamin B 12

2005
Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial.
    JAMA, 2005, 03-02, Volume: 293, Issue:9

    Topics: Aged; Bone Density; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Hemiplegia; Hip Fractures; Homocysteine; Humans; Male; Risk Factors; Stroke; Vitamin B 12

2005
Methylenetetrahydrofolate reductase polymorphisms and homocysteine-lowering effect of vitamin therapy in Singaporean stroke patients.
    Stroke, 2006, Volume: 37, Issue:2

    Topics: Aged; Coronary Artery Disease; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Middle Aged; Models, Statistical; Placebos; Polymorphism, Genetic; Regression Analysis; Risk Factors; Singapore; Stroke; Vitamin B 12; Vitamin B 6; Vitamins

2006
Homocysteine, MTHFR C677 T, vitamin B12, and folate levels in Thai children with ischemic stroke: a case-control study.
    Journal of pediatric hematology/oncology, 2006, Volume: 28, Issue:12

    Topics: Adolescent; Child; Child, Preschool; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Ischemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors; Stroke; Thailand; Thrombosis; Vitamin B 12

2006
Assessment of pre- and post-methionine load homocysteine for prediction of recurrent stroke and coronary artery disease in the Vitamin Intervention for Stroke Prevention Trial.
    Atherosclerosis, 2008, Volume: 200, Issue:2

    Topics: Aged; Cohort Studies; Coronary Artery Disease; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Myocardial Infarction; Prospective Studies; Recurrence; Risk; Stroke; Vitamins

2008
Impairment of cerebrovascular reactivity by methionine-induced hyperhomocysteinemia and amelioration by quinapril treatment.
    Stroke, 2000, Volume: 31, Issue:12

    Topics: Adult; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Endothelium, Vascular; Female; Homocysteine; Humans; Isoquinolines; Male; Methionine; Middle Aged; Quinapril; Stroke; Tetrahydroisoquinolines; Ultrasonography, Doppler, Transcranial

2000
Plasma homocysteine concentrations in the acute and convalescent periods of atherothrombotic stroke.
    Stroke, 2001, Volume: 32, Issue:1

    Topics: Acute Disease; Adult; Aged; Arteriosclerosis; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Convalescence; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Lipids; Male; Middle Aged; Regression Analysis; Risk Factors; Scotland; Stroke; Stroke Rehabilitation; Tomography, X-Ray Computed; Vitamin B 12

2001
Cerebrovascular events in patients with significant stenosis of the carotid artery are associated with hyperhomocysteinemia and platelet antigen-1 (Leu33Pro) polymorphism.
    Stroke, 2001, Dec-01, Volume: 32, Issue:12

    Topics: Aged; Amino Acid Substitution; Antibodies, Antiphospholipid; Antigens, Human Platelet; Carotid Stenosis; Comorbidity; Factor V; Female; Homocysteine; Humans; Hyperhomocysteinemia; Integrin beta3; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Platelet Membrane Glycoproteins; Polymorphism, Genetic; Prothrombin; Risk Assessment; Risk Factors; Stroke

2001
Changes in plasma homocyst(e)ine in the acute phase after stroke.
    Stroke, 2002, Volume: 33, Issue:2

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Demography; Female; Homocysteine; Homocystine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Prospective Studies; Risk Factors; Sample Size; Stroke; Time Factors; Tomography, X-Ray Computed

2002
The VITATOPS (Vitamins to Prevent Stroke) Trial: rationale and design of an international, large, simple, randomised trial of homocysteine-lowering multivitamin therapy in patients with recent transient ischaemic attack or stroke.
    Cerebrovascular diseases (Basel, Switzerland), 2002, Volume: 13, Issue:2

    Topics: Biomarkers; Brain; Disease Progression; Double-Blind Method; Follow-Up Studies; Homocysteine; Humans; Ischemic Attack, Transient; Magnetic Resonance Imaging; Risk Factors; Stroke; Time Factors; Treatment Outcome; Vitamins

2002
Risk factors for progression of aortic atheroma in stroke and transient ischemic attack patients.
    Stroke, 2002, Volume: 33, Issue:4

    Topics: Anticoagulants; Aortic Diseases; Arteriosclerosis; Demography; Disease Progression; Echocardiography, Transesophageal; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Remission, Spontaneous; Risk Factors; Stroke; Treatment Outcome

2002

Other Studies

349 other study(ies) available for homocysteine and Stroke

ArticleYear
Elevated albumin-to-creatinine ratio as a risk factor for stroke and homocysteine as an effect modifier in hypertensive Asian individuals.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2022, Volume: 45, Issue:1

    Topics: Albumins; Creatinine; Homocysteine; Humans; Risk Factors; Stroke

2022
Association Between Hyperhomocysteinemia Combined with Metabolic Syndrome and Higher Prevalence of Stroke in Chinese Adults Who Have Elevated Blood Pressure.
    Medical science monitor : international medical journal of experimental and clinical research, 2022, Jan-11, Volume: 28

    Topics: Aged; Biomarkers; Blood Pressure Determination; China; Comorbidity; Correlation of Data; Female; Heart Disease Risk Factors; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Metabolic Syndrome; Prevalence; Risk Assessment; Stroke

2022
Association of the methylenetetrahydrofolate reductase (
    The Journal of international medical research, 2022, Volume: 50, Issue:2

    Topics: Brain Ischemia; Case-Control Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Ischemic Stroke; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Stroke

2022
The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction.
    Bioengineered, 2022, Volume: 13, Issue:3

    Topics: Animals; Blood-Brain Barrier; Butorphanol; Claudin-5; Endothelial Cells; Homocysteine; Interleukin-6; Mice; Stroke

2022
Homocysteine can aggravate depressive like behaviors in a middle cerebral artery occlusion/reperfusion rat model: a possible role for NMDARs-mediated synaptic alterations.
    Nutritional neuroscience, 2023, Volume: 26, Issue:6

    Topics: Animals; Dizocilpine Maleate; Homocysteine; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion; Stroke

2023
A Study of Srum Homocysteine Level in Ischaemic Stoke.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Aged; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Ischemic Stroke; Lipids; Risk Factors; Stroke; Vitamin B 12

2022
Role of Serum Homocysteine, C-Reactive Protein (CRP), Uric Acid & Pro-Brain Natriuretic Peptide (Pro-BNP) in Predicting the Functional Outcome in Patients with Ischemic Stroke- A Prospective Observational Study from North India.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Adult; Aged; Biomarkers; Brain Ischemia; C-Reactive Protein; Embolic Stroke; Female; Homocysteine; Humans; Ischemic Stroke; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Prognosis; Risk Factors; Stroke; Uric Acid

2022
Plasma Total Homocysteine Level Is Related to Unfavorable Outcomes in Ischemic Stroke With Atrial Fibrillation.
    Journal of the American Heart Association, 2022, 05-03, Volume: 11, Issue:9

    Topics: Aged; Atrial Fibrillation; Female; Homocysteine; Humans; Ischemic Stroke; Kidney Diseases; Male; Prospective Studies; Risk Factors; Stroke

2022
Clinical Significance of Peptidase M20 Domain Containing 1 Ii Patients with Carotid Atherosclerosis.
    Arquivos brasileiros de cardiologia, 2022, Volume: 119, Issue:3

    Topics: Amidohydrolases; Biomarkers; C-Reactive Protein; Carotid Artery Diseases; Cholesterol; Homocysteine; Humans; Leptin; Peptide Hydrolases; Plaque, Atherosclerotic; Risk Factors; Stroke; Triglycerides; Tumor Necrosis Factors

2022
Clinical characteristics of cognitive impairment and its related risk factors in post-stroke epilepsy
    Epileptic disorders : international epilepsy journal with videotape, 2022, 08-01, Volume: 24, Issue:4

    Topics: Adult; Anticonvulsants; Brain Ischemia; Cognitive Dysfunction; Epilepsy; Homocysteine; Humans; Risk Factors; Stroke

2022
Ischemic Stroke and Dietary Vitamin B12 Deficiency in Old-Aged Females: Impaired Motor Function, Increased Ischemic Damage Size, and Changed Metabolite Profiles in Brain and Cecum Tissue.
    Nutrients, 2022, Jul-19, Volume: 14, Issue:14

    Topics: Animals; Brain; Cecum; Diet; Female; Folic Acid; Homocysteine; Ischemic Stroke; Mice; Stroke; Vitamin B 12; Vitamin B 12 Deficiency

2022
Juvenile patients with the homozygous MTHFR C677T genotype develop ischemic stroke 5 years earlier than wild type.
    Journal of thrombosis and thrombolysis, 2022, Volume: 54, Issue:2

    Topics: Brain Ischemia; Genotype; Homocysteine; Humans; Ischemic Stroke; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Retrospective Studies; Stroke

2022
Risk factors and their correlation with severity of cerebral microbleed in acute large artery atherosclerotic cerebral infarction patients.
    Clinical neurology and neurosurgery, 2022, Volume: 221

    Topics: Arteries; Brain Ischemia; Cerebral Hemorrhage; Cerebral Infarction; Cholesterol; Homocysteine; Humans; Hypertension; Magnetic Resonance Imaging; Risk Factors; Stroke

2022
Correlation between Collateral Compensation and Homocysteine Levels in Patients with Acute Cerebral Infarction after Intravenous Thrombolysis Based on Medical Big Data.
    BioMed research international, 2022, Volume: 2022

    Topics: Acute Disease; Big Data; Brain Ischemia; Cerebral Infarction; Homocysteine; Humans; Stroke; Thrombolytic Therapy

2022
Binary effects of intravascular laser irradiation of blood on motor recovery and homocysteine reduction in a case with ischemic hemiparesis: portrayed with brain perfusion images.
    BMC neurology, 2022, Sep-27, Volume: 22, Issue:1

    Topics: Brain; Cerebrovascular Circulation; Homocysteine; Humans; Ischemia; Lasers; Male; Middle Aged; Paresis; Perfusion; Stroke; Tomography, Emission-Computed, Single-Photon

2022
Large-Scale Targeted Sequencing Study of Ischemic Stroke in the Han Chinese Population.
    Journal of the American Heart Association, 2022, 10-04, Volume: 11, Issue:19

    Topics: Aldehyde Dehydrogenase, Mitochondrial; Asian People; Case-Control Studies; China; Genetic Predisposition to Disease; Homocysteine; Humans; Ischemic Stroke; Polymorphism, Single Nucleotide; Risk Factors; Stroke; Transcription Factors

2022
Relationship between MTHFR C677T, homocysteine, and ischemic stroke in a large sample of the Han Chinese population.
    Medicine, 2022, Sep-23, Volume: 101, Issue:38

    Topics: Blood Glucose; Case-Control Studies; China; Cholesterol; Genotype; Homocysteine; Humans; Ischemic Stroke; Methylenetetrahydrofolate Reductase (NADPH2); Stroke; Triglycerides

2022
Related factors based on non-targeted metabolomics methods in minor ischaemic stroke.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Biomarkers; Blood Glucose; Brain Ischemia; C-Reactive Protein; Homocysteine; Humans; Hypertension; Ischemic Stroke; Lactic Acid; Methylamines; Oxides; Pyruvic Acid; Stroke

2022
Correlation between Vitamin D, homocysteine and brain-derived neurotrophic factor levels in patients with ischemic stroke.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:21

    Topics: Brain-Derived Neurotrophic Factor; Homocysteine; Humans; Ischemic Stroke; Stroke; Vitamin D; Vitamins

2022
Evaluation of serum levels of homocysteine and C-reactive protein in patients with ischemic stroke.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: C-Reactive Protein; Constriction, Pathologic; Homocysteine; Humans; Hypertension; Ischemic Stroke; Risk Factors; Stroke

2022
MTHFR C677T polymorphism, homocysteine, burden, and location of AMI and ACI.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:4

    Topics: Brain Ischemia; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Infarction; Stroke

2023
Elevated levels of total homocysteine after ischemic stroke: a potential marker for in-hospital outcomes.
    Neurological research, 2023, Volume: 45, Issue:6

    Topics: Cardiovascular Diseases; Female; Homocysteine; Humans; Ischemic Stroke; Logistic Models; Male; Risk Factors; Stroke

2023
An interpretable machine learning approach for predicting 30-day readmission after stroke.
    International journal of medical informatics, 2023, Volume: 174

    Topics: Aged; Electronic Health Records; Female; Homocysteine; Humans; Machine Learning; Male; Patient Readmission; Stroke

2023
Ischaemic stroke with multi-focal venous and arterial thrombosis due to hyperhomocysteinemia: anabolic androgenic steroid use and MTHFR c.667 C > T variant - a case report.
    BMC neurology, 2023, Apr-26, Volume: 23, Issue:1

    Topics: Anabolic Androgenic Steroids; Brain Ischemia; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Stroke; Male; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Stroke; Thrombosis; Vitamin B 12

2023
Reply to Letter to the Editor "Ischemic stroke and homocysteine: To test or not to test?"
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2023, Volume: 42, Issue:11

    Topics: Homocysteine; Humans; Ischemic Stroke; Risk Factors; Stroke

2023
Ischemic stroke and homocysteine: To test or not to test?
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2023, Volume: 42, Issue:11

    Topics: Brain Ischemia; Homocysteine; Humans; Ischemic Stroke; Risk Factors; Stroke

2023
Factors influencing TCM syndrome types of acute cerebral infarction: A binomial logistic regression analysis.
    Medicine, 2023, Nov-17, Volume: 102, Issue:46

    Topics: Brain Ischemia; Cerebral Infarction; Cholesterol; Homocysteine; Humans; Logistic Models; Medicine, Chinese Traditional; Stroke; Syndrome; Triglycerides; Uric Acid

2023
Association between homocysteine and multivascular atherosclerosis in stroke-related vascular beds determined by three-dimensional magnetic resonance vessel wall imaging.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 70

    Topics: Adult; Aged; Atherosclerosis; Biomarkers; Female; Homocysteine; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Angiography; Male; Middle Aged; Plaque, Atherosclerotic; Sensitivity and Specificity; Stroke

2019
From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis.
    Brain and behavior, 2019, Volume: 9, Issue:10

    Topics: Adult; Blood Urea Nitrogen; Brain Ischemia; C-Reactive Protein; China; Cholesterol, LDL; Correlation of Data; Female; Homocysteine; Humans; Male; Medicine, Chinese Traditional; Middle Aged; Patient Selection; Qi; Stroke; Yin Deficiency

2019
S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset.
    Biochimica et biophysica acta. General subjects, 2020, Volume: 1864, Issue:1

    Topics: Amyloid Neuropathies, Familial; Cardiomyopathies; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Homocysteine; Humans; Methionine; Mutation; Myocytes, Cardiac; Prealbumin; Protein Conformation; Protein Stability; Stroke; Structure-Activity Relationship

2020
A Clinical study to determine levels of vitamin B12,Folic acid and Homocysteine in patients of Ischemic stroke.
    The Journal of the Association of Physicians of India, 2020, Volume: 68, Issue:1

    Topics: Brain Ischemia; Folic Acid; Homocysteine; Humans; Ischemic Stroke; Stroke; Vitamin B 12

2020
A prospective cohort study of MTHFR C677T gene polymorphism and its influence on the therapeutic effect of homocysteine in stroke patients with hyperhomocysteinemia.
    BMC neurology, 2020, Apr-11, Volume: 20, Issue:1

    Topics: Adult; Aged; Alleles; Cohort Studies; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prospective Studies; Risk Factors; Stroke

2020
Identifying gene-environment interactions on the efficacy of folic acid therapy for hyperhomocysteinemia based on prediction model.
    Nutrition research (New York, N.Y.), 2020, Volume: 77

    Topics: Aged; Algorithms; Coronary Disease; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Machine Learning; Male; Middle Aged; Models, Theoretical; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Stroke; Treatment Failure; Treatment Outcome

2020
Value of plasma homocysteine to predict stroke, cardiovascular diseases, and new-onset hypertension: A retrospective cohort study.
    Medicine, 2020, Aug-21, Volume: 99, Issue:34

    Topics: Adult; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Stroke

2020
[Aminothiols in blood plasma at different subtypes of ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2020, Volume: 120, Issue:8. Vyp. 2

    Topics: Aged; Atherosclerosis; Brain Ischemia; Cysteine; Glutathione; Homocysteine; Humans; Middle Aged; Oxidation-Reduction; Stroke

2020
Yet Another Way to Lower Homocysteine: Close the Patent Foramen Ovale.
    Neurology, 2021, 07-13, Volume: 97, Issue:2

    Topics: Foramen Ovale, Patent; Homocysteine; Humans; Stroke

2021
Effect of Patent Foramen Ovale Closure After Stroke on Circulatory Biomarkers.
    Neurology, 2021, 07-13, Volume: 97, Issue:2

    Topics: Adult; Biomarkers; Female; Foramen Ovale, Patent; Homocysteine; Humans; Male; Mass Spectrometry; Middle Aged; Prospective Studies; Stroke

2021
Synergistic Effect of the
    Journal of diabetes research, 2017, Volume: 2017

    Topics: Aged; Asian People; Brain Ischemia; Case-Control Studies; China; Diabetes Mellitus, Type 2; Epoxide Hydrolases; Female; Genetic Predisposition to Disease; Glycated Hemoglobin; Haplotypes; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk; Stroke

2017
The Impact of Homocysteine, Vitamin B12, and Vitamin D Levels on Functional Outcome after First-Ever Ischaemic Stroke.
    BioMed research international, 2017, Volume: 2017

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Homocysteine; Humans; Male; Middle Aged; Recovery of Function; Stroke; Vitamin B 12; Vitamin D

2017
Combination of High-Sensitivity C-Reactive Protein and Homocysteine Predicts the Post-Stroke Depression in Patients with Ischemic Stroke.
    Molecular neurobiology, 2018, Volume: 55, Issue:4

    Topics: Adult; Aged; Brain Ischemia; C-Reactive Protein; Depression; Female; Follow-Up Studies; Homocysteine; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; ROC Curve; Stroke

2018
The role of phenylephrine in patients with small deep subcortical infarct and progressive weakness.
    Journal of the neurological sciences, 2017, Jun-15, Volume: 377

    Topics: Aged; Anticoagulants; C-Reactive Protein; Cerebral Infarction; Disease Progression; Female; Hemoglobins; Homocysteine; Humans; Hypertension; Magnetic Resonance Imaging; Male; Middle Aged; Phenylephrine; Pulse Wave Analysis; Regression Analysis; Retrospective Studies; Stroke; Tomography Scanners, X-Ray Computed; Vasoconstrictor Agents

2017
Association of lower serum Brain-derived neurotrophic factor levels with larger infarct volumes in acute ischemic stroke.
    Journal of neuroimmunology, 2017, 06-15, Volume: 307

    Topics: Aged; Blood Glucose; Brain Infarction; Brain Ischemia; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Case-Control Studies; Diffusion Magnetic Resonance Imaging; Female; Homocysteine; Humans; Male; Middle Aged; Retrospective Studies; Stroke

2017
Insulin resistance and elevated C-reactive protein among first-degree relatives of ischemic stroke patients.
    Diabetes & metabolic syndrome, 2017, Volume: 11 Suppl 2

    Topics: Adult; Atherosclerosis; Brain Ischemia; C-Reactive Protein; Family; Female; Homocysteine; Humans; Insulin Resistance; Lipids; Male; Middle Aged; Stroke

2017
Evidence for interactions between homocysteine and genistein: insights into stroke risk and potential treatment.
    Metabolic brain disease, 2017, Volume: 32, Issue:6

    Topics: Bacillus subtilis; Genistein; Glutathione Peroxidase; Homocysteine; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; Risk Factors; Stroke; Vibrio

2017
Relevance of plasma levels of free homocysteine and methionine as risk predictors for ischemic stroke in the young.
    Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Odds Ratio; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6; Young Adult

2018
Elevated plasma homocysteine upon ischemic stroke is associated with increased long-term mortality in women.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Prognosis; Registries; Retrospective Studies; Sex Factors; Stroke; Survival Analysis; Survival Rate

2017
Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke.
    Journal of neuroinflammation, 2017, Sep-18, Volume: 14, Issue:1

    Topics: Animals; Brain Ischemia; Homocysteine; Inflammation; Male; Microglia; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Stroke

2017
Interplay between 3'-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke.
    Scientific reports, 2017, 09-29, Volume: 7, Issue:1

    Topics: 3' Untranslated Regions; Aged; Brain Ischemia; Case-Control Studies; Female; Folic Acid; Gene Expression; Gene-Environment Interaction; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; Stroke

2017
The relationship between serum CXCL16 level and carotid vulnerable plaque in patients with ischemic stroke.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:17

    Topics: Aged; Body Mass Index; Carotid Artery, Internal; Carotid Intima-Media Thickness; Chemokine CXCL16; Female; Homocysteine; Humans; Male; Middle Aged; Plaque, Atherosclerotic; Risk Factors; Stroke; Ultrasonography, Doppler, Transcranial

2017
Early neurological deterioration during the acute phase as a predictor of long-term outcome after first-ever ischemic stroke.
    Medicine, 2017, Volume: 96, Issue:51

    Topics: Age Factors; Body Mass Index; C-Reactive Protein; China; Coronary Disease; Diabetes Complications; Disease Progression; Female; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Factors; Stroke

2017
A possible synergistic effect of MTHFR C677T polymorphism on homocysteine level variations increased risk for ischemic stroke.
    Medicine, 2017, Volume: 96, Issue:51

    Topics: Asian People; Biomarkers; Case-Control Studies; China; Female; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Stroke

2017
The SNP Rs915014 in MTHFR Regulated by MiRNA Associates with Atherosclerosis.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:3

    Topics: Aged; Alcohol Drinking; Antagomirs; Asian People; Atherosclerosis; Case-Control Studies; Female; HEK293 Cells; Homocysteine; Humans; Hypertension; Lipoproteins, HDL; Male; Methylenetetrahydrofolate Reductase (NADPH2); MicroRNAs; Middle Aged; Polymorphism, Single Nucleotide; Smoking; Stroke

2018
Association between homocysteine and conventional predisposing factors on risk of stroke in patients with hypertension.
    Scientific reports, 2018, 03-01, Volume: 8, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Atherosclerosis; Biomarkers; Blood Pressure; Brain Ischemia; Case-Control Studies; Cohort Studies; Essential Hypertension; Female; Homocysteine; Humans; Hypertension; Logistic Models; Male; Middle Aged; Odds Ratio; Prospective Studies; Retrospective Studies; Risk Factors; Stroke

2018
Which Ischemic Stroke Subtype Is Associated with Hyperhomocysteinemia?
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:7

    Topics: Adult; Biomarkers; Brain Ischemia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Risk Factors; Stroke

2018
Tagging Functional Polymorphism in 3' Untranslated Region of Methylene Tetrahydrofolate Reductase and Risk of Ischemic Stroke.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 46, Issue:3

    Topics: 3' Untranslated Regions; Alleles; Base Sequence; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Gene Frequency; Genotype; HEK293 Cells; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); MicroRNAs; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Protein Binding; Risk; Sequence Alignment; Stroke

2018
Serum Calcium is Related to the Degree of Artery Stenosis in Acute Ischemic Stroke.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 46, Issue:3

    Topics: Adult; Aged; Calcium; Cluster Analysis; Constriction, Pathologic; Databases, Factual; Down-Regulation; Female; Homocysteine; Humans; Lipoproteins, LDL; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Protein Interaction Maps; Retrospective Studies; Stroke; Tomography, X-Ray Computed; Up-Regulation; Uric Acid

2018
Changes in total homocysteine levels after acute stroke and recurrence of stroke.
    Scientific reports, 2018, 05-03, Volume: 8, Issue:1

    Topics: Aged; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Recurrence; Risk Assessment; Stroke

2018
B Vitamins for Stroke Prevention: Interaction of Low Platelet Count and High Plasma Total Homocysteine.
    Journal of the American College of Cardiology, 2018, 05-15, Volume: 71, Issue:19

    Topics: Folic Acid; Homocysteine; Humans; Platelet Count; Stroke; Vitamin B Complex

2018
Homocysteine is Associated with Exaggerated Morning Blood Pressure Surge in Patients with Acute Ischemic Stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:10

    Topics: Aged; Biomarkers; Blood Pressure; Brain Ischemia; Circadian Rhythm; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Risk Factors; Stroke; Time Factors

2018
Decreased functional connectivity within the default-mode network in acute brainstem ischemic stroke.
    European journal of radiology, 2018, Volume: 105

    Topics: Biomarkers; Brain Ischemia; Brain Stem; Cognition Disorders; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Prefrontal Cortex; Signal Processing, Computer-Assisted; Stroke

2018
A genetic deficiency in folic acid metabolism impairs recovery after ischemic stroke.
    Experimental neurology, 2018, Volume: 309

    Topics: Animals; Apoptosis; Astrocytes; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Embryo, Mammalian; Female; Folic Acid; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Homocysteine; Male; Metabolic Diseases; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Neurons; Psychomotor Performance; Recovery of Function; Stroke

2018
The serum homocysteine level in patients with acute ischemic stroke (AIS) after thrombolysis and its relationship with clinical outcomes.
    Revista da Associacao Medica Brasileira (1992), 2018, Volume: 64, Issue:5

    Topics: Administration, Intravenous; Aged; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Risk Factors; ROC Curve; Severity of Illness Index; Stroke; Thrombolytic Therapy

2018
Astragaloside IV reversed the autophagy and oxidative stress induced by the intestinal microbiota of AIS in mice.
    Journal of microbiology (Seoul, Korea), 2018, Volume: 56, Issue:11

    Topics: Animals; Antioxidants; Autophagy; Autophagy-Related Protein 12; Bacteria; Beclin-1; Brain; Disease Models, Animal; Fatty Acids; Feces; Gastrointestinal Microbiome; Genetic Vectors; Glutathione; Homocysteine; Ischemic Attack, Transient; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; NADPH Oxidase 2; NADPH Oxidase 4; Oxidative Stress; Reactive Oxygen Species; Saponins; Stroke; Superoxide Dismutase; Triterpenes

2018
Association between plasma homocysteine and hypertension: Results from a cross-sectional and longitudinal analysis in Beijing's adult population from 2012 to 2017.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:11

    Topics: Adult; Beijing; Biomarkers; Cross-Sectional Studies; Female; Heart Diseases; Homocysteine; Humans; Hypertension; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Renal Insufficiency; Risk Factors; Stroke

2018
Plasma homocysteine levels and intracranial plaque characteristics: association and clinical relevance in ischemic stroke.
    BMC neurology, 2018, Dec-06, Volume: 18, Issue:1

    Topics: Aged; Biomarkers; Female; Homocysteine; Humans; Intracranial Arteriosclerosis; Magnetic Resonance Imaging; Male; Middle Aged; Risk Factors; ROC Curve; Stroke

2018
High-sensitivity C reactive protein and risk of cardiovascular disease in China-CVD study.
    Journal of epidemiology and community health, 2019, Volume: 73, Issue:2

    Topics: Adult; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; China; Coronary Disease; Female; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Risk Assessment; Risk Factors; Stroke

2019
The telomere length of peripheral blood cells is associated with the risk of ischemic stroke in Han population of northern China.
    Medicine, 2019, Volume: 98, Issue:7

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Asian People; Biomarkers; China; Female; Homocysteine; Humans; Male; Middle Aged; Real-Time Polymerase Chain Reaction; Risk Factors; ROC Curve; Stroke; Telomere

2019
Homocysteine and small vessel stroke: A mendelian randomization analysis.
    Annals of neurology, 2019, Volume: 85, Issue:4

    Topics: Brain Ischemia; Homocysteine; Humans; Mendelian Randomization Analysis; Microvessels; Polymorphism, Single Nucleotide; Stroke; Vitamin B 12

2019
The relationship between plasma homocysteine levels and MTHFR gene variation, age, and sex in Northeast China.
    Nigerian journal of clinical practice, 2019, Volume: 22, Issue:3

    Topics: Adult; Age Factors; Aged; Asian People; Cardiovascular Diseases; China; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Sex Factors; Stroke

2019
CBS promoter hypermethylation increases the risk of hypertension and stroke.
    Clinics (Sao Paulo, Brazil), 2019, 03-21, Volume: 74

    Topics: Adult; Age Factors; Aged; Asian People; Biomarkers; Case-Control Studies; Cystathionine beta-Synthase; DNA Methylation; Female; Homocysteine; Humans; Hypertension; Male; Middle Aged; Promoter Regions, Genetic; Risk Assessment; Sex Factors; Stroke

2019
Platelet counts affect the prognostic value of homocysteine in acute ischemic stroke patients.
    Atherosclerosis, 2019, Volume: 285

    Topics: Aged; Brain Ischemia; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Platelet Count; Prognosis; Prospective Studies; Risk Factors; Stroke

2019
Methylation in the TP53 promoter is associated with ischemic stroke.
    Molecular medicine reports, 2019, Volume: 20, Issue:2

    Topics: Age Factors; Brain Ischemia; Carotid Intima-Media Thickness; Case-Control Studies; DNA Methylation; Female; Homocysteine; Humans; Male; Middle Aged; Promoter Regions, Genetic; Sex Characteristics; Stroke; Tumor Suppressor Protein p53

2019
Elevated homocysteine as an independent risk for intracranial atherosclerotic stenosis.
    Aging, 2019, 06-12, Volume: 11, Issue:11

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Homocysteine; Humans; Intracranial Arteriosclerosis; Magnetic Resonance Angiography; Male; Middle Aged; Risk Factors; Stroke

2019
Hyperhomocysteinemia in female migraineurs of childbearing ages.
    Ideggyogyaszati szemle, 2019, May-30, Volume: 72, Issue:5-6

    Topics: Adolescent; Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Migraine Disorders; Migraine with Aura; Migraine without Aura; Reproductive Health; Risk Factors; Stroke; Young Adult

2019
Association of Glasgow Coma Scale with Total Homocysteine Levels in Patients with Hemorrhagic Stroke.
    Annals of nutrition & metabolism, 2019, Volume: 75, Issue:1

    Topics: Aged; Blood Pressure; China; Cholesterol; Cross-Sectional Studies; Female; Glasgow Coma Scale; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Smoking; Stroke

2019
Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke.
    Cell death & disease, 2019, 07-22, Volume: 10, Issue:8

    Topics: Adenine; Animals; Autophagy; Brain Ischemia; Cell Death; Cell Survival; Cells, Cultured; Disease Models, Animal; Homocysteine; Male; MAP Kinase Signaling System; Neural Stem Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Stroke; TOR Serine-Threonine Kinases

2019
Meta-analysis of B vitamin supplementation on plasma homocysteine, cardiovascular and all-cause mortality.
    Clinical nutrition (Edinburgh, Scotland), 2013, Volume: 32, Issue:2

    Topics: Coronary Disease; Dietary Supplements; Homocysteine; Humans; Myocardial Infarction; Stroke; Vitamin B Complex

2013
Hyperhomocysteinemia associates with small vessel disease more closely than large vessel disease.
    International journal of medical sciences, 2013, Volume: 10, Issue:4

    Topics: Aged; Brain Ischemia; Cerebral Arteries; Female; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Middle Aged; Radiography; Risk Factors; Stroke

2013
Racial-ethnic differences in stroke risk factors and subtypes: results of a prospective hospital-based registry.
    The International journal of neuroscience, 2013, Volume: 123, Issue:8

    Topics: Adolescent; Adult; Aged; Asian People; Black or African American; Ethnicity; Female; Hispanic or Latino; Homocysteine; Hospitals; Humans; Male; Middle Aged; Prevalence; Prospective Studies; Registries; Risk Factors; Sex Characteristics; Stroke; United States; White People

2013
Methylenetetrahydrofolate reductase (C677T and A1298C) polymorphisms, hyperhomocysteinemia, and ischemic stroke in Tunisian patients.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2013, Volume: 22, Issue:4

    Topics: Adult; Aged; Biomarkers; Brain Ischemia; Case-Control Studies; Chi-Square Distribution; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Phenotype; Polymorphism, Genetic; Risk Factors; Stroke; Tunisia; Up-Regulation

2013
[Homocysteine levels and platelet aggregation in patients with cerebral circulatory disorders].
    Terapevticheskii arkhiv, 2013, Volume: 85, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Brain Ischemia; Cerebrovascular Circulation; Collagen; Female; Homocysteine; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation; Severity of Illness Index; Stroke

2013
C-reactive protein and homocysteine predict long-term mortality in young ischemic stroke patients.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2013, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Age Factors; Biomarkers; Brain Ischemia; C-Reactive Protein; Cause of Death; Comorbidity; Disability Evaluation; Female; Homocysteine; Humans; Kaplan-Meier Estimate; Linear Models; Male; Middle Aged; Norway; Prognosis; Proportional Hazards Models; Registries; Retrospective Studies; Risk Factors; Stroke; Time Factors; Young Adult

2013
Is plasma homocysteine related to severity and outcome of atherothrombotic stroke? Comment on: acute phase homocysteine related to severity and outcome of atherothrombotic stroke.
    European journal of internal medicine, 2014, Volume: 25, Issue:1

    Topics: Atherosclerosis; Female; Homocysteine; Humans; Male; Stroke; Thrombosis

2014
Combination of high-sensitivity C-reactive protein and homocysteine predicts the short-term outcomes of Chinese patients with acute ischemic stroke.
    Neurological research, 2013, Volume: 35, Issue:9

    Topics: Aged; Asian People; Brain; Brain Ischemia; C-Reactive Protein; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Prognosis; Prospective Studies; ROC Curve; Severity of Illness Index; Stroke

2013
Acute phase homocysteine related to severity and outcome of atherothrombotic stroke - reply.
    European journal of internal medicine, 2014, Volume: 25, Issue:1

    Topics: Atherosclerosis; Female; Homocysteine; Humans; Male; Stroke; Thrombosis

2014
Stroke in a young man.
    BMJ (Clinical research ed.), 2013, Jul-15, Volume: 347

    Topics: Adult; Betaine; Cystathionine beta-Synthase; Diet, Protein-Restricted; Homocysteine; Homocystinuria; Humans; Lipotropic Agents; Male; Methionine; Platelet Aggregation Inhibitors; Pyridoxine; Stroke; Treatment Outcome; Vision Disorders; Vitamin B Complex

2013
Multiple presence of prothrombotic risk factors in Croatian children with arterial ischemic stroke and transient ischemic attack.
    Croatian medical journal, 2013, Volume: 54, Issue:4

    Topics: Adolescent; Antithrombin III; Blood Coagulation Disorders; Child; Cholesterol; Croatia; Female; Homocysteine; Humans; Ischemic Attack, Transient; Lupus Coagulation Inhibitor; Male; Protein C; Protein S; Risk Factors; Stroke

2013
Relationship between metformin use, vitamin B12 deficiency, hyperhomocysteinemia and vascular complications in patients with type 2 diabetes.
    Endocrine journal, 2013, Volume: 60, Issue:12

    Topics: Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Japan; Male; Metformin; Middle Aged; Prevalence; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 12 Deficiency

2013
[Prevention of ischemic stroke by homocysteine-lowering therapy: lack of consistent evidence].
    Zhonghua nei ke za zhi, 2013, Volume: 52, Issue:9

    Topics: Down-Regulation; Homocysteine; Humans; Recurrence; Stroke; Vitamin B 12; Vitamin B 6

2013
MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification.
    European journal of nutrition, 2014, Volume: 53, Issue:7

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Denmark; Dyslipidemias; Female; Folic Acid; Follow-Up Studies; Genotype; Genotyping Techniques; Homocysteine; Humans; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Stroke; Triglycerides; Vitamin B 12; Young Adult

2014
Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene rs4073259 polymorphism not associated with ischemic stroke in the northeastern Chinese Han population.
    Clinical neurology and neurosurgery, 2014, Volume: 119

    Topics: 5-Lipoxygenase-Activating Proteins; Adult; Aged; Asian People; Brain Ischemia; Carotid Artery Diseases; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Plaque, Atherosclerotic; Polymorphism, Single Nucleotide; Severity of Illness Index; Sex Factors; Stroke

2014
Homocysteine-lowering therapy and risk of recurrent stroke, myocardial infarction and death: the impact of age in the VISP trial.
    Cerebrovascular diseases (Basel, Switzerland), 2014, Volume: 37, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Stroke; Vitamin B 12; Vitamins

2014
Effect of genetic variants associated with plasma homocysteine levels on stroke risk.
    Stroke, 2014, Volume: 45, Issue:7

    Topics: Brain Ischemia; Cohort Studies; Europe; Genetic Association Studies; Genetic Loci; Genetic Predisposition to Disease; Genetic Variation; Genome; Homocysteine; Humans; Polymorphism, Single Nucleotide; Risk; Stroke

2014
Homocysteine, small-vessel disease, and atherosclerosis: an MRI study of 825 stroke patients.
    Neurology, 2014, Aug-19, Volume: 83, Issue:8

    Topics: Atherosclerosis; Brain Ischemia; Cerebral Arteries; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Retrospective Studies; Risk Factors; Stroke

2014
Early markers of occult megaloblastosis for low-cost detection of hyperhomocysteinemia in patients with ischaemic stroke: preventive approach for primary health care.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:9

    Topics: Anemia, Megaloblastic; Biomarkers; Brain Ischemia; Early Diagnosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neutrophils; Primary Health Care; Stroke; Vitamin B 12

2014
High homocysteine and blood pressure related to poor outcome of acute ischemia stroke in Chinese population.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Aged; Blood Pressure; Brain Ischemia; China; Female; Homocysteine; Humans; Male; Middle Aged; Stroke

2014
Correlation of post-stroke fatigue with glucose, homocysteine and functional disability.
    Acta neurologica Scandinavica, 2015, Volume: 131, Issue:6

    Topics: Aged; Blood Glucose; Case-Control Studies; Fatigue; Female; Homocysteine; Humans; Male; Middle Aged; Stroke

2015
The long-term effects of pitavastatin on blood lipids and platelet activation markers in stroke patients: impact of the homocysteine level.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Aged; Aged, 80 and over; Atherosclerosis; Biomarkers; C-Reactive Protein; Carotid Arteries; Demography; Female; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Middle Aged; Platelet Activation; Quinolines; Retrospective Studies; Risk Factors; Stroke; Ultrasonography; von Willebrand Factor

2014
Effects of differences in serum total homocysteine, folate, and vitamin B12 on cognitive impairment in stroke patients.
    BMC neurology, 2014, Nov-30, Volume: 14

    Topics: Adult; Aged; Brain; Case-Control Studies; Cognition; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12

2014
Relationship of MTHFR gene 677C → T polymorphism, homocysteine, and estimated glomerular filtration rate levels with the risk of new-onset diabetes.
    Medicine, 2015, Volume: 94, Issue:7

    Topics: Adult; Asian People; Diabetes Mellitus; Female; Genotype; Glomerular Filtration Rate; Homocysteine; Humans; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Risk Factors; Sex Factors; Stroke

2015
Metabolic determinants of white matter hyperintensity burden in patients with ischemic stroke.
    Atherosclerosis, 2015, Volume: 240, Issue:1

    Topics: Aged; Aged, 80 and over; Algorithms; Biomarkers; Boston; Brain Ischemia; Endothelium, Vascular; Female; Glycated Hemoglobin; Homocysteine; Humans; Leukoencephalopathies; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Factors; Severity of Illness Index; Signal Processing, Computer-Assisted; Stroke; Up-Regulation

2015
Frequency of hyper-homocysteinaemia in ischaemic stroke patients of Karachi.
    JPMA. The Journal of the Pakistan Medical Association, 2014, Volume: 64, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Stroke

2014
Effect of a pre-microRNA-149 (miR-149) genetic variation on the risk of ischemic stroke in a Chinese Han population.
    Genetics and molecular research : GMR, 2015, Mar-30, Volume: 14, Issue:1

    Topics: Aged; Asian People; Brain Ischemia; China; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; MicroRNAs; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Risk; Stroke

2015
Serum Levels of High-sensitivity C-Reactive Protein at Admission Are More Strongly Associated with Poststroke Depression in Acute Ischemic Stroke than Homocysteine Levels.
    Molecular neurobiology, 2016, Volume: 53, Issue:4

    Topics: Aged; Aged, 80 and over; C-Reactive Protein; Depression; Female; Homocysteine; Hospitalization; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; ROC Curve; Stroke

2016
Biomarkers Related to Carotid Intima-Media Thickness and Plaques in Long-Term Survivors of Ischemic Stroke.
    Translational stroke research, 2015, Volume: 6, Issue:4

    Topics: Adult; Biomarkers; Blood Sedimentation; Brain Ischemia; C-Reactive Protein; Carotid Intima-Media Thickness; Cholesterol; Female; Homocysteine; Humans; Interleukin-10; Longitudinal Studies; Male; Middle Aged; Polymorphism, Genetic; Receptors, IgG; Retrospective Studies; Risk Factors; Stroke; Survivors

2015
Association between homocysteine and incidence of ischemic stroke in subjects with essential hypertension: a matched case-control study.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:7

    Topics: Aged; Brain Ischemia; Case-Control Studies; China; Essential Hypertension; Female; Homocysteine; Humans; Hypertension; Incidence; Logistic Models; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Factors; Stroke

2015
Aldehyde dehydrogenase 2 polymorphism as a protective factor for intracranial vascular stenosis in ischemic stroke in Han Chinese.
    The International journal of neuroscience, 2016, Volume: 126, Issue:4

    Topics: Alcohol Drinking; Aldehyde Dehydrogenase; Alleles; Asian People; Case-Control Studies; Constriction, Pathologic; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Intracranial Arterial Diseases; Magnetic Resonance Angiography; Male; Middle Aged; Mutation; Polymorphism, Genetic; Protective Factors; Risk Factors; Stroke

2016
Homocysteine, Ischemic Stroke, and Coronary Heart Disease in Hypertensive Patients: A Population-Based, Prospective Cohort Study.
    Stroke, 2015, Volume: 46, Issue:7

    Topics: Adult; Aged; Brain Ischemia; China; Cohort Studies; Coronary Disease; Female; Homocysteine; Humans; Hypertension; Longitudinal Studies; Male; Middle Aged; Population Surveillance; Prospective Studies; Risk Factors; Stroke

2015
A Fast Multiple-Kernel Method With Applications to Detect Gene-Environment Interaction.
    Genetic epidemiology, 2015, Volume: 39, Issue:6

    Topics: Algorithms; Gene-Environment Interaction; Genetic Variation; Homocysteine; Humans; Models, Genetic; Quantitative Trait Loci; Regression Analysis; Risk Factors; Software; Stroke; Vitamins

2015
Elevated Total Homocysteine Levels in Acute Ischemic Stroke Are Associated With Long-Term Mortality.
    Stroke, 2015, Volume: 46, Issue:9

    Topics: Aged; Brain Ischemia; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Prognosis; Recurrence; Stroke

2015
Prognostic Significance of Homocysteine Levels in Acute Ischemic Stroke: A Prospective Cohort Study.
    Current neurovascular research, 2015, Volume: 12, Issue:4

    Topics: Aged; Brain Ischemia; Cohort Studies; Female; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Prognosis; Prospective Studies; Sensitivity and Specificity; Statistics, Nonparametric; Stroke

2015
[A prospective study on the association of plasma homocysteine level with stroke in hypertensive patients].
    Zhonghua nei ke za zhi, 2015, Volume: 54, Issue:4

    Topics: Antihypertensive Agents; Coronary Artery Disease; Coronary Disease; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hypertension; Incidence; Male; Prospective Studies; Socioeconomic Factors; Stroke

2015
[A nested case-control study on the relationship of three kinds of cytokines and risk of cardio-cerebrovascular events among Inner Mongolians].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2015, Volume: 49, Issue:3

    Topics: Cardiovascular Diseases; Case-Control Studies; Cytokines; Homocysteine; Humans; Hypertension; Intercellular Adhesion Molecule-1; Logistic Models; Prevalence; Risk; Risk Factors; Stroke; von Willebrand Factor

2015
H-Type hypertension, stroke and diabetes in China: Opportunities for primary prevention.
    Journal of diabetes, 2016, Volume: 8, Issue:1

    Topics: China; Diabetes Mellitus, Type 2; Folic Acid; Homocysteine; Humans; Hypertension; Stroke; Vitamin B Complex

2016
Homocysteine Level Is Associated with White Matter Hyperintensity Locations in Patients with Acute Ischemic Stroke.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Brain Ischemia; Female; Follow-Up Studies; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Prognosis; Prospective Studies; Stroke; White Matter

2015
Homocysteine-lowering therapy and early functional outcomes of ischemic patients with H-type hypertension: a retrospective analysis of CNSR.
    Australasian physical & engineering sciences in medicine, 2015, Volume: 38, Issue:4

    Topics: Aged; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Prognosis; Stroke; Treatment Outcome

2015
Long-Term Mortality and Its Risk Factors in Stroke Survivors.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016, Volume: 25, Issue:3

    Topics: Adult; Aged; Creatinine; Female; Hemoglobins; Homocysteine; Humans; Kaplan-Meier Estimate; Longitudinal Studies; Male; Middle Aged; Risk Factors; Stroke; Survivors

2016
Association of High Homocysteine Levels With the Risk Stratification in Hypertensive Patients at Risk of Stroke.
    Clinical therapeutics, 2016, Volume: 38, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Cholesterol; Cholesterol, HDL; Cross-Sectional Studies; Female; Homocysteine; Humans; Hypertension; Lipids; Male; Middle Aged; Prevalence; Risk Factors; Stroke; Triglycerides; Young Adult

2016
Homocysteinemia and early outcome of acute ischemic stroke in elderly patients.
    Brain and behavior, 2016, Volume: 6, Issue:5

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Outcome Assessment, Health Care; Stroke

2016
Methylenetetrahydrofolate reductase C677T polymorphism, hypertension and risk of stroke: a prospective, nested case-control study.
    The International journal of neuroscience, 2017, Volume: 127, Issue:3

    Topics: Adult; Aged; Case-Control Studies; China; Fasting; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hypertension; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Prospective Studies; Risk Factors; Stroke

2017
H-Type Hypertension and C Reactive Protein in Recurrence of Ischemic Stroke.
    International journal of environmental research and public health, 2016, 05-07, Volume: 13, Issue:5

    Topics: Brain Ischemia; C-Reactive Protein; China; Diabetes Mellitus; Female; Homocysteine; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Recurrence; Stroke

2016
The model homologue of the partially defective human 5,10-methylenetetrahydrofolate reductase, considered as a risk factor for stroke due to increased homocysteine level, can be protected and reactivated by heat shock proteins.
    Metabolic brain disease, 2016, Volume: 31, Issue:5

    Topics: Heat-Shock Proteins; Homocysteine; Hot Temperature; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Stroke

2016
Daytime sleepiness is associated with hyperhomocysteinemia in rural area of China: A cross-sectional study.
    European journal of internal medicine, 2016, Volume: 35

    Topics: Adult; Aged; Apnea; China; Coronary Disease; Cross-Sectional Studies; Disorders of Excessive Somnolence; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Risk Factors; Sex Factors; Sleep; Snoring; Stroke; Surveys and Questionnaires

2016
Independent Correlation of Serum Homocysteine with Cerebral Microbleeds in Patients with Acute Ischemic Stroke due to Large-Artery Atherosclerosis.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016, Volume: 25, Issue:11

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Cerebral Hemorrhage; China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Magnetic Resonance Imaging; Male; Middle Aged; Prognosis; Risk Factors; Severity of Illness Index; Stroke; Up-Regulation

2016
Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study.
    Neurology, 2016, Sep-20, Volume: 87, Issue:12

    Topics: Biomarkers; Brain Ischemia; C-Reactive Protein; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Prognosis; Proportional Hazards Models; Receptors, Tumor Necrosis Factor, Type II; Risk; Stroke; Vascular Endothelial Growth Factor A

2016
Elevated Homocysteine Level Related to Poor Outcome After Thrombolysis in Acute Ischemic Stroke.
    Medical science monitor : international medical journal of experimental and clinical research, 2016, Sep-15, Volume: 22

    Topics: Aged; Cohort Studies; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Prognosis; Retrospective Studies; Risk Factors; Severity of Illness Index; Stroke; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome

2016
Homocysteine concentration in coronary artery disease: Influence of three common single nucleotide polymorphisms.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2017, Volume: 27, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Area Under Curve; Biomarkers; Case-Control Studies; Chi-Square Distribution; Coronary Artery Disease; Cystathionine beta-Synthase; Disease Progression; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homozygote; Humans; Kaplan-Meier Estimate; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Phenotype; Polymorphism, Single Nucleotide; Predictive Value of Tests; Proportional Hazards Models; Risk Assessment; Risk Factors; ROC Curve; Stroke; Time Factors

2017
Prognostic Value of C-Reactive Protein and Homocysteine in Large-Artery Atherosclerotic Stroke: a Prospective Observational Study.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:3

    Topics: Aged; Arteriolosclerosis; C-Reactive Protein; Female; Homocysteine; Humans; Male; Middle Aged; Prognosis; Prospective Studies; Regression Analysis; Retrospective Studies; Statistics, Nonparametric; Stroke

2017
Serum Klotho (but not haplotypes) associate with the post-myocardial infarction status of older adults.
    Clinics (Sao Paulo, Brazil), 2016, Dec-01, Volume: 71, Issue:12

    Topics: Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Anthropometry; Biomarkers; C-Reactive Protein; Coronary Artery Disease; Cross-Sectional Studies; Energy Intake; Enzyme-Linked Immunosorbent Assay; Female; Genotyping Techniques; Glucuronidase; Haplotypes; Homocysteine; Humans; Klotho Proteins; Male; Middle Aged; Myocardial Infarction; Nutrition Assessment; Reference Values; Risk Factors; Sex Factors; Statistics, Nonparametric; Stroke

2016
Dl-3-n-butylphthalide can improve the cognitive function of patients with acute ischemic stroke: a prospective intervention study.
    Neurological research, 2017, Volume: 39, Issue:4

    Topics: Benzofurans; Biomarkers; Brain Ischemia; C-Reactive Protein; Cognition; Dementia, Vascular; Female; Homocysteine; Humans; Logistic Models; Male; Mental Status Schedule; Middle Aged; Multivariate Analysis; Neuroprotective Agents; Neuropsychological Tests; Nootropic Agents; Prospective Studies; Risk Factors; Stroke; Treatment Outcome

2017
Methylene Tetrahydrofolate Reductase (MTHFR) rs868014 Polymorphism Regulated by miR-1203 Associates with Risk and Short Term Outcome of Ischemic Stroke.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 41, Issue:2

    Topics: Aged; Alleles; Binding Sites; Case-Control Studies; Female; Gene Frequency; Genotype; HEK293 Cells; Homocysteine; Humans; Hypertension; Linkage Disequilibrium; Lipoproteins, HDL; Lipoproteins, LDL; Male; Methylenetetrahydrofolate Reductase (NADPH2); MicroRNAs; Middle Aged; Polymorphism, Single Nucleotide; Risk; Smoking; Stroke

2017
Serum levels of homocysteine at admission are associated with post-stroke depression in acute ischemic stroke.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017, Volume: 38, Issue:5

    Topics: Aged; Brain Ischemia; Depression; Female; Follow-Up Studies; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Patient Admission; Psychiatric Status Rating Scales; ROC Curve; Statistics, Nonparametric; Stroke; Tomography, X-Ray Computed

2017
Association between hyperhomocysteinemia and stroke with atherosclerosis and small artery occlusion depends on homocysteine metabolism-related vitamin levels in Chinese patients with normal renal function.
    Metabolic brain disease, 2017, Volume: 32, Issue:3

    Topics: Aged; Aged, 80 and over; Asian People; Case-Control Studies; Cerebrovascular Disorders; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Kidney; Male; Middle Aged; Retrospective Studies; Stroke; Vitamin B 12

2017
Elevated Plasma Homocysteine Level Increased the Risk of Early Renal Impairment in Acute Ischemic Stroke Patients.
    Cellular and molecular neurobiology, 2017, Volume: 37, Issue:8

    Topics: Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Case-Control Studies; China; Cystatin C; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Middle Aged; Retrospective Studies; Risk Factors; Stroke

2017
Association of Polymorphisms in Coagulation Factor Genes and Enzymes of Homocysteine Metabolism With Arterial Ischemic Stroke in Children.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2017, Volume: 23, Issue:8

    Topics: Adolescent; Amino Acid Substitution; Blood Coagulation Factors; Brain Ischemia; Case-Control Studies; Child; Child, Preschool; Female; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Genetic; Stroke

2017
Increased homocysteine-induced release of excitatory amino acids in the striatum of spontaneously hypertensive stroke-prone rats.
    Brain research, 2008, Aug-21, Volume: 1226

    Topics: Analysis of Variance; Animals; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acids; Homocysteine; Male; Microdialysis; Rats; Rats, Inbred SHR; Stroke

2008
Prognostic value of free plasma homocysteine levels in patients hospitalized with acute coronary syndrome.
    The American journal of cardiology, 2008, Jul-15, Volume: 102, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Chromatography, High Pressure Liquid; Female; Homocysteine; Hospitalization; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke

2008
Exploratory study of plasma total homocysteine and its relationship to short-term outcome in acute ischaemic stroke in Nigerians.
    BMC neurology, 2008, Jul-12, Volume: 8

    Topics: Aged; Black People; Case-Control Studies; Diabetes Complications; Female; Fluorescence Polarization Immunoassay; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Ischemia; Male; Middle Aged; Nigeria; Outcome Assessment, Health Care; Prevalence; Prospective Studies; Regression Analysis; Risk Factors; Severity of Illness Index; Smoking; Stroke; Survival Rate

2008
Homocysteine and stroke prevention: have the trials settled the issue?
    International journal of stroke : official journal of the International Stroke Society, 2006, Volume: 1, Issue:4

    Topics: Clinical Trials as Topic; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamins

2006
Homocysteine and its relationship to stroke subtypes in a UK black population: the south London ethnicity and stroke study.
    Stroke, 2008, Volume: 39, Issue:11

    Topics: Age Factors; Aged; Black People; Cerebrovascular Disorders; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Leukoaraiosis; London; Male; Middle Aged; Risk Factors; Sex Factors; Stroke; Vitamin B Complex

2008
Homocysteine reduces endothelial progenitor cells in stroke patients through apoptosis.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009, Volume: 29, Issue:1

    Topics: Apoptosis; Caspase 3; Caspase 8; Cells, Cultured; Cytochromes c; Endothelial Cells; Enzyme Activation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stem Cells; Stroke; Vitamins

2009
Cryptogenic stroke and patent foramen ovale: clinical clues to paradoxical embolism.
    Journal of the neurological sciences, 2008, Dec-15, Volume: 275, Issue:1-2

    Topics: Adult; Blood Coagulation Tests; Embolism, Paradoxical; Female; Foramen Ovale, Patent; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Retrospective Studies; Risk Factors; Stroke; Ultrasonography, Doppler, Transcranial; Vitamin B 12

2008
Associations between serum selenium and total plasma homocysteine during the acute phase of ischaemic stroke.
    European neurology, 2008, Volume: 60, Issue:6

    Topics: Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Plasma; Selenium; Stroke

2008
Homocysteine: the Rubik's cube of cardiovascular risk factors.
    Mayo Clinic proceedings, 2008, Volume: 83, Issue:11

    Topics: Atherosclerosis; Biomarkers; Coronary Disease; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Hypertension; Inflammation Mediators; Myocardial Infarction; Platelet Activation; Research Design; Risk Assessment; Risk Factors; Smoking; Stroke; Vascular Cell Adhesion Molecule-1; Vitamin B Complex

2008
A note on homocysteine levels in children.
    Thrombosis research, 2009, Volume: 123, Issue:5

    Topics: Brain Ischemia; Child; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Stroke

2009
Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population.
    European journal of neurology, 2008, Volume: 15, Issue:12

    Topics: Acute Disease; Asian People; Brain Ischemia; DNA Mutational Analysis; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitric Oxide Synthase Type III; Nitrites; Polymorphism, Genetic; Singapore; Stroke

2008
The role of homocysteine as a significant risk factor for white matter lesions in Japanese women with rheumatoid arthritis.
    Metabolism: clinical and experimental, 2009, Volume: 58, Issue:1

    Topics: Arthritis, Rheumatoid; Blood Glucose; Blood Pressure; Brain Diseases; Cholesterol; Cross-Sectional Studies; Dyslipidemias; Female; Heart Rate; Homocysteine; Humans; Japan; Logistic Models; Magnetic Resonance Imaging; Middle Aged; Multivariate Analysis; Stroke; Triglycerides

2009
Are plasma homocysteine levels related to neurological severity and functional outcome after ischemic stroke in the Korean population?
    Journal of the neurological sciences, 2009, Mar-15, Volume: 278, Issue:1-2

    Topics: Aged; Brain Ischemia; Female; Homocysteine; Humans; Korea; Male; Models, Statistical; Neuropsychological Tests; Prognosis; Risk Factors; Stroke

2009
The art of primary prevention and risk assessment: homocysteine revisited.
    Stroke, 2009, Volume: 40, Issue:3

    Topics: Biomarkers; Cerebrovascular Circulation; Homocysteine; Humans; Risk Assessment; Stroke; Vitamin B Complex

2009
[Vitamin B substitution. No protection for the heart -- but for the brain!].
    MMW Fortschritte der Medizin, 2008, Dec-11, Volume: 150, Issue:51-52

    Topics: Cohort Studies; Controlled Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Meta-Analysis as Topic; Myocardial Infarction; Prospective Studies; Retrospective Studies; Risk Factors; Stroke; Time Factors; Vitamin B 12; Vitamin B 6

2008
Increased prevalence of hyperhomocysteinemia in cervical artery dissection causing stroke: a case-control study.
    Cerebrovascular diseases (Basel, Switzerland), 2009, Volume: 27, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Case-Control Studies; Cervical Vertebrae; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Odds Ratio; Prevalence; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Thrombosis; Vertebral Artery Dissection; Young Adult

2009
Relationship of homocysteine with other risk factors and outcome of ischemic stroke.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:4

    Topics: Adult; Aged; Brain Ischemia; Comorbidity; Diabetes Mellitus; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; India; Male; Middle Aged; Obesity; Risk Factors; Severity of Illness Index; Smoking; Stroke; Tomography, X-Ray Computed; Vitamin B 12

2009
[Neuropsychological complications after coronary bypass grafting].
    Fortschritte der Neurologie-Psychiatrie, 2009, Volume: 77, Issue:2

    Topics: Aged; Aged, 80 and over; Apolipoproteins E; Cause of Death; Coronary Artery Bypass; Female; Genotype; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Myocardial Ischemia; Nervous System Diseases; Postoperative Complications; Prospective Studies; Stroke; Treatment Outcome

2009
[Strategy for stroke prevention: controlling both hypertension and high homocysteine].
    Zhonghua yi xue za zhi, 2008, Dec-23, Volume: 88, Issue:47

    Topics: China; Homocysteine; Humans; Hypertension; Preventive Medicine; Stroke

2008
[Relationship between smoking and homocysteine concentration in ischemic stroke patients].
    Zhonghua yi xue za zhi, 2008, Dec-23, Volume: 88, Issue:47

    Topics: Aged; Brain Ischemia; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Sex Factors; Smoking; Stroke; Vitamin B 12

2008
Urinary methylmalonic acid levels in patients with acute ischemic stroke.
    Clinical biochemistry, 2009, Volume: 42, Issue:7-8

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Stroke; Vitamin B 12

2009
Homocysteine and lipoprotein (a) correlation in ischemic stroke patients.
    Journal of the neurological sciences, 2009, Jun-15, Volume: 281, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Brain Ischemia; Cholesterol; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Lipoprotein(a); Male; Middle Aged; Odds Ratio; Smoking; Stroke; Young Adult

2009
Vasculopathic and thrombophilic risk factors for spontaneous preterm birth.
    International journal of epidemiology, 2009, Volume: 38, Issue:3

    Topics: Adult; Case-Control Studies; Cholesterol, HDL; Coronary Disease; Enzyme-Linked Immunosorbent Assay; Female; Gestational Age; Homocysteine; Humans; Infant, Newborn; Placenta; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications, Cardiovascular; Premature Birth; Prospective Studies; Risk Factors; Stroke; Young Adult

2009
Association of plasma homocysteine concentration with cerebral white matter hyperintensity on magnetic resonance images in stroke patients.
    Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2

    Topics: Animals; Axons; Brain; Cerebral Arterial Diseases; Comorbidity; Diabetes Mellitus; Dyslipidemias; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipids; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Obesity; Prevalence; Risk; Smoking; Stroke; Taiwan

2009
Blood levels of homocysteine, cysteine, glutathione, folic acid, and vitamin B12 in the acute phase of atherothrombotic stroke.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2009, Volume: 30, Issue:4

    Topics: Acute Disease; Aged; Aged, 80 and over; Brain Ischemia; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12; Vitamins

2009
High plasma homocysteine levels contribute to the risk of stroke recurrence and all-cause mortality in a large prospective stroke population.
    Clinical science (London, England : 1979), 2009, Oct-26, Volume: 118, Issue:3

    Topics: Adult; Aged; Biomarkers; China; Epidemiologic Methods; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Recurrence; Stroke

2009
Use of serum homocysteine to predict stroke, coronary heart disease and death in ethnic Chinese. 12-year prospective cohort study.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:8

    Topics: Adult; Aged; China; Cohort Studies; Coronary Disease; Death; Homocysteine; Humans; Middle Aged; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; ROC Curve; Stroke

2009
Homocysteine and stroke: another brick in the wall.
    Clinical science (London, England : 1979), 2009, Oct-26, Volume: 118, Issue:3

    Topics: Biomarkers; Female; Homocysteine; Humans; Male; Recurrence; Risk Factors; Stroke

2009
Homocysteine and pulsatility index of cerebral arteries.
    Stroke, 2009, Volume: 40, Issue:10

    Topics: Aged; Basilar Artery; Blood Pressure; Brain Ischemia; Carotid Stenosis; Cerebral Arteries; Cerebrovascular Circulation; Female; Homocysteine; Humans; Male; Middle Aged; Middle Cerebral Artery; Neovascularization, Physiologic; Predictive Value of Tests; Pulsatile Flow; Severity of Illness Index; Stroke; Ultrasonography, Doppler, Transcranial; Vertebral Artery

2009
Homocysteine and ischemic stroke subtype: a relationship study in Chinese patients.
    Neurological research, 2010, Volume: 32, Issue:6

    Topics: Aged; Analysis of Variance; Brain Ischemia; China; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Leukoaraiosis; Male; Middle Aged; Retrospective Studies; Risk Factors; Stroke

2010
Folate status of Ghanaian populations in London and Accra.
    The British journal of nutrition, 2010, Volume: 103, Issue:3

    Topics: Adult; Black People; Educational Status; Erythrocytes; Fasting; Female; Folic Acid; Ghana; Guinea; Homocysteine; Humans; Incidence; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Polymorphism, Single Nucleotide; Smoking; Stroke; Urban Population; Vitamin B 12

2010
Plasma homocysteine levels after acute stroke and in the convalescent phase.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2009, Volume: 36, Issue:6

    Topics: Adult; Convalescence; Female; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Stroke; Young Adult

2009
Enhanced TLR4 endothelial cell immunohistochemical expression in symptomatic carotid atherosclerotic plaques.
    Expert opinion on therapeutic targets, 2010, Volume: 14, Issue:1

    Topics: Aged; Amaurosis Fugax; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Atherosclerosis; C-Reactive Protein; Carotid Arteries; Carotid Stenosis; Endarterectomy, Carotid; Endothelial Cells; Female; Graft Occlusion, Vascular; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Ischemic Attack, Transient; Male; Stroke; Thrombosis; Toll-Like Receptor 4

2010
Strong independent correlation of proteinuria with cerebral microbleeds in patients with stroke and transient ischemic attack.
    Archives of neurology, 2010, Volume: 67, Issue:1

    Topics: Atrial Fibrillation; Biomarkers; Brain; Cerebral Arteries; Cerebral Hemorrhage; Cross-Sectional Studies; Diffusion Magnetic Resonance Imaging; Female; Homocysteine; Humans; Ischemic Attack, Transient; Male; Middle Aged; Proteinuria; Risk Factors; Sex Distribution; Stroke

2010
Association between homocysteine and endothelial dysfunction markers in stroke disease.
    Nutritional neuroscience, 2010, Volume: 13, Issue:1

    Topics: Adult; Aged; Biomarkers; Blood Glucose; Brain Ischemia; C-Reactive Protein; Creatinine; E-Selectin; Endothelium, Vascular; Female; Homocysteine; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Stroke; Time Factors; Vascular Cell Adhesion Molecule-1; Vascular Diseases; Vitamin B Complex

2010
Magnetic resonance angiography findings in patients with ischemic stroke from North India.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2010, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Biomarkers; Blood Glucose; Body Mass Index; Brain Ischemia; Carotid Artery, External; Carotid Artery, Internal; Diabetes Mellitus; Feeding Behavior; Female; Folic Acid; Homocysteine; Humans; Hypertension; India; Lipids; Magnetic Resonance Angiography; Male; Middle Aged; Racial Groups; Risk Factors; Socioeconomic Factors; Stroke; Vitamin B 12; Young Adult

2010
MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:5

    Topics: Adult; Aged; Boston; Cardiovascular Diseases; Cognition Disorders; DNA Damage; Female; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Hypertension; Life Style; Male; Memory; Methionine Adenosyltransferase; Middle Aged; Puerto Rico; Stroke; Vitamin B 6

2010
Homocysteine, vitamin B12 and folate levels in Iranian patients with ischemic stroke.
    Neurological research, 2010, Volume: 32, Issue:9

    Topics: Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Iran; Male; Middle Aged; Stroke; Vitamin B 12

2010
Determinants of white matter hyperintensity volume in patients with acute ischemic stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2010, Volume: 19, Issue:3

    Topics: Adult; Aged; Aging; Biomarkers; Brain; Brain Ischemia; Cohort Studies; Coronary Artery Disease; Female; Homocysteine; Humans; Hypertension; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neurologic Examination; Retrospective Studies; Risk Factors; Stroke

2010
Does the progeny of premature ischemic stroke sufferers need intensive interest of physicians oriented toward primary prevention? A pilot study.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2010, Volume: 17, Issue:6

    Topics: Adult; Age of Onset; Analysis of Variance; Biomarkers; Brain Ischemia; Case-Control Studies; Female; Fibrinogen; Genetic Predisposition to Disease; Heredity; Homocysteine; Humans; Lipids; Logistic Models; Male; Odds Ratio; Pedigree; Phenotype; Pilot Projects; Poland; Primary Prevention; Risk Assessment; Risk Factors; Stroke; Young Adult

2010
Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:2

    Topics: Adolescent; Adult; Age of Onset; Aged; Brain Ischemia; Case-Control Studies; Chi-Square Distribution; Child; Female; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Italy; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Stroke; Young Adult

2010
Genetic linkage of serum homocysteine in Dominican families: the Family Study of Stroke Risk and Carotid Atherosclerosis.
    Stroke, 2010, Volume: 41, Issue:7

    Topics: Adult; Carotid Artery Diseases; Dominican Republic; Female; Genetic Linkage; Homocysteine; Humans; Male; Middle Aged; New York City; Risk Factors; Stroke

2010
Association of carotid plaque Lp-PLA(2) with macrophages and Chlamydia pneumoniae infection among patients at risk for stroke.
    PloS one, 2010, Jun-09, Volume: 5, Issue:6

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aged; Aged, 80 and over; Carotid Arteries; Chlamydia Infections; Chlamydophila pneumoniae; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Immunohistochemistry; Male; Middle Aged; Risk Factors; Stroke

2010
Genetic polymorphisms of Chinese patients with ischemic stroke and concurrent stenoses of extracranial and intracranial vessels.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:10

    Topics: Aged; Aged, 80 and over; Aryldialkylphosphatase; Asian People; Constriction, Pathologic; Female; Genetic Testing; Glutamate-Cysteine Ligase; Homocysteine; Humans; Lipid Metabolism; Lipoproteins, LDL; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Stroke; Ultrasonography, Doppler, Duplex; Valine

2010
Homocysteine and internal carotid artery occlusion in ischemic stroke.
    Journal of atherosclerosis and thrombosis, 2010, Sep-30, Volume: 17, Issue:9

    Topics: Aged; Blood Flow Velocity; Brain Ischemia; Carotid Stenosis; Female; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Risk Factors; Stroke; Vascular Resistance

2010
Association between tumor necrosis factor-alpha (-308G→A and -238G→A) polymorphisms and homocysteine levels in patients with ischemic strokes and silent brain infarctions.
    Cerebrovascular diseases (Basel, Switzerland), 2010, Volume: 30, Issue:5

    Topics: Aged; Alleles; Brain Infarction; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Korea; Male; Middle Aged; Polymorphism, Single Nucleotide; Sex Characteristics; Stroke; Tumor Necrosis Factor-alpha

2010
Pronounced association of elevated serum homocysteine with stroke in subgroups of individuals: a nationwide study.
    Journal of the neurological sciences, 2010, Nov-15, Volume: 298, Issue:1-2

    Topics: Age Distribution; Analysis of Variance; Ethnicity; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hypercholesterolemia; Logistic Models; Male; Middle Aged; Risk Factors; Sex Distribution; Smoking; Stroke; Treatment Outcome

2010
Plasma total homocysteine and the methylenetetrahydrofolate reductase 677C>T polymorphism do not contribute to the distribution of cervico-cerebral atherosclerosis in ischaemic stroke patients.
    European journal of neurology, 2011, Volume: 18, Issue:3

    Topics: Aged; Atherosclerosis; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Immunoassay; Magnetic Resonance Angiography; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Stroke

2011
[Prothrombotic disturbances in children after ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2009, Volume: 109, Issue:12 Suppl 2

    Topics: Adolescent; Blood Coagulation Factors; Child; Child, Preschool; Homocysteine; Humans; Infant; Polymorphism, Genetic; Prothrombin; Stroke; Thrombophilia

2009
The vital amines: too much of a good thing?: comment on "Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality".
    Archives of internal medicine, 2010, Oct-11, Volume: 170, Issue:18

    Topics: Cardiovascular Diseases; Cause of Death; Folic Acid; Homocysteine; Humans; Neoplasms; Randomized Controlled Trials as Topic; Stroke; Vitamin B Complex

2010
Elevated homocysteine and C-reactive protein levels independently predict worsening prognosis after stroke in Chinese patients.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2010, Volume: 30, Issue:5

    Topics: Aged; Asian People; C-Reactive Protein; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Prognosis; Prospective Studies; Risk Factors; Stroke

2010
Mendelian randomisation: a tool for assessing causality in observational epidemiology.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 713

    Topics: Alcohol Drinking; Blood Pressure; Causality; Coronary Disease; Fibrinogen; Homocysteine; Humans; Mendelian Randomization Analysis; Molecular Epidemiology; Stroke

2011
The enigma of ENIGMA-I.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:2

    Topics: Anesthetics, Inhalation; Biomarkers; Cause of Death; Homocysteine; Humans; Myocardial Infarction; Nitrous Oxide; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Stroke; Surgical Procedures, Operative; Survival Rate; Time Factors; Treatment Outcome

2011
Hyperhomocysteinemia, obesity and cryptogenic stroke.
    Clinical hemorheology and microcirculation, 2011, Volume: 47, Issue:1

    Topics: Adult; Case-Control Studies; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Obesity; Risk Factors; Stroke

2011
Evaluation of MTHFR C677T polymorphism in ischemic and hemorrhagic stroke patients. A case-control study in a Northern Indian population.
    Journal of the neurological sciences, 2011, May-15, Volume: 304, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Ischemia; Case-Control Studies; Child; Child, Preschool; Female; Genetic Association Studies; Homocysteine; Humans; India; Intracranial Hemorrhages; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Stroke; Young Adult

2011
Are stroke biomarkers seeing brain vessels in patients with ischemic stroke?: a C-reactive protein and homocysteine study.
    Stroke, 2011, Volume: 42, Issue:5

    Topics: Aged; Biomarkers; Brain; C-Reactive Protein; Cerebral Arteries; Coronary Artery Disease; Coronary Vessels; Female; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Retrospective Studies; Stroke

2011
Left atrial enlargement: a cause of stroke?
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011, Jul-12, Volume: 183, Issue:10

    Topics: Biomarkers; C-Reactive Protein; Cardiomegaly; Heart Atria; Homocysteine; Humans; Life Style; Lipoproteins; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Stroke

2011
Prospective study of first stroke in relation to plasma homocysteine and MTHFR 677C>T and 1298A>C genotypes and haplotypes - evidence for an association with hemorrhagic stroke.
    Clinical chemistry and laboratory medicine, 2011, Volume: 49, Issue:9

    Topics: Adult; Aged; Disease-Free Survival; Female; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Hemorrhage; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Prospective Studies; Stroke

2011
TT genotype of the methylenetetrahydrofolate reductase C677T polymorphism is an important determinant for homocysteine levels in multi-ethnic Malaysian ischaemic stroke patients.
    Annals of the Academy of Medicine, Singapore, 2011, Volume: 40, Issue:4

    Topics: China; Ethnicity; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Malaysia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Genetic; Stroke; Vitamin B 12

2011
Association between VEGF polymorphisms and homocysteine levels in patients with ischemic stroke and silent brain infarction.
    Stroke, 2011, Volume: 42, Issue:9

    Topics: Aged; Alleles; Asian People; Brain Infarction; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Korea; Male; Middle Aged; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors; Stroke; Vascular Endothelial Growth Factor A

2011
Folate and cardiovascular disease: one size does not fit all.
    Lancet (London, England), 2011, Aug-13, Volume: 378, Issue:9791

    Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Stroke; Vitamin B Complex

2011
Statin treatment is associated with reduced toll-like receptor 4 immunohistochemical expression on carotid atherosclerotic plaques: a novel effect of statins.
    Vascular, 2011, Volume: 19, Issue:6

    Topics: Aged; C-Reactive Protein; Carotid Arteries; Carotid Stenosis; Endarterectomy; Female; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Ischemic Attack, Transient; Male; Risk Factors; Stroke; Toll-Like Receptor 4

2011
Association between plasma homocysteine levels and obstructive sleep apnoea in patients with ischaemic stroke.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:11

    Topics: Aged; Brain Ischemia; Cross-Sectional Studies; Female; Homocysteine; Humans; Hypertension; Male; Middle Aged; Obesity; Prospective Studies; Sleep Apnea, Obstructive; Stroke

2011
A comprehensive association analysis of homocysteine metabolic pathway genes in Singaporean Chinese with ischemic stroke.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Asian People; Female; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Singapore; Stroke

2011
Transcobalamin 2 variant associated with poststroke homocysteine modifies recurrent stroke risk.
    Neurology, 2011, Oct-18, Volume: 77, Issue:16

    Topics: Adult; Aged; Female; Genetic Association Studies; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Stroke; Transcobalamins

2011
Increased plasma levels of total homocysteine but not asymmetric dimethylarginine in Hispanic subjects with ischemic stroke FREC-VI sub-study.
    European journal of neurology, 2012, Volume: 19, Issue:3

    Topics: Aged; Arginine; Case-Control Studies; Colombia; Female; Hispanic or Latino; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Stroke

2012
Estimated glomerular filtration rate decline in 567 patients with acute stroke.
    Scandinavian journal of urology and nephrology, 2012, Volume: 46, Issue:2

    Topics: Aged; Brain Ischemia; China; Confidence Intervals; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperuricemia; Intracranial Hemorrhages; Male; Middle Aged; Odds Ratio; Prevalence; Prospective Studies; Renal Insufficiency, Chronic; Smoking; Stroke

2012
Understanding the complexity of homocysteine lowering with vitamins: the potential role of subgroup analyses.
    JAMA, 2011, Dec-21, Volume: 306, Issue:23

    Topics: Cardiovascular Diseases; Clinical Trials as Topic; Data Interpretation, Statistical; Homocysteine; Humans; Kidney; Meta-Analysis as Topic; Methylenetetrahydrofolate Dehydrogenase (NADP); Polymorphism, Genetic; Reproducibility of Results; Risk Assessment; Stroke; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2011
Plasma, aqueous and vitreous homocysteine levels in proliferative diabetic retinopathy.
    The British journal of ophthalmology, 2012, Volume: 96, Issue:5

    Topics: Adult; Aged; Aqueous Humor; Case-Control Studies; Diabetic Retinopathy; Female; Homocysteine; Humans; Hypercholesterolemia; Hypertension; Kidney Diseases; Luminescent Measurements; Male; Middle Aged; Myocardial Ischemia; Stroke; Vitreous Body

2012
Effectiveness of B vitamins on the control of hypertension and stroke events of SHRSP rats.
    Journal of dietary supplements, 2010, Volume: 7, Issue:1

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Antioxidants; Ataxia; Blood Pressure; Dietary Supplements; Folic Acid; Homocysteine; Hypertension; Ischemia; Male; Malondialdehyde; Oxidative Stress; Postural Balance; Pyridoxine; Rats; Rats, Inbred SHR; Riboflavin; Seizures; Stroke; Treatment Outcome; Vitamin B Complex

2010
Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study.
    Circulation, 2012, May-01, Volume: 125, Issue:17

    Topics: Aged; Albuminuria; Biomarkers; Blood Proteins; Brain; Brain Injuries; Cohort Studies; Creatinine; Endothelium, Vascular; Female; Hemostasis; Homocysteine; Hormones; Humans; Incidence; Inflammation; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Aged; Organ Size; Prospective Studies; Risk; Stroke; United States

2012
Rapid cycling bipolar affective disorder and recurrent strokes secondary to high blood homocysteine.
    Journal of mental health (Abingdon, England), 2014, Volume: 23, Issue:5

    Topics: Bipolar Disorder; Depression; Homocysteine; Humans; Male; Middle Aged; Stroke

2014
Lipid peroxidation dysregulation in ischemic stroke: plasma 4-HNE as a potential biomarker?
    Biochemical and biophysical research communications, 2012, Sep-07, Volume: 425, Issue:4

    Topics: Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Biomarkers; Brain; Cell Survival; Homocysteine; Humans; Lipid Peroxidation; Male; Neurons; Oxidative Stress; PC12 Cells; Rats; Rats, Inbred SHR; Stroke

2012
Paraoxonase 1 L55M, Q192R and paraoxonase 2 S311C alleles in atherothrombosis.
    Molecular and cellular biochemistry, 2013, Volume: 374, Issue:1-2

    Topics: Alleles; Aryldialkylphosphatase; Cysteine; Female; Genetic Predisposition to Disease; Genotype; Glutathione; Homocysteine; Humans; Hypertension; Ischemic Attack, Transient; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Middle Aged; Myocardial Infarction; Oxidative Stress; Polymorphism, Single Nucleotide; Risk Factors; Stroke; Thrombosis

2013
Prediction of ischemic stroke in young Indians: is thrombophilia profiling a way out?
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2013, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Antithrombin III; Brain Ischemia; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; India; Lupus Coagulation Inhibitor; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Prognosis; Protein C; Protein C Deficiency; Protein S; Protein S Deficiency; Prothrombin; Stroke; Thrombophilia

2013
The effects of lipoprotein(a) and homocysteine on prognosis and risk factors in acute ischemic stroke.
    The International journal of neuroscience, 2013, Volume: 123, Issue:8

    Topics: Aged; Biomarkers; Brain Ischemia; Case-Control Studies; Female; Homocysteine; Humans; Lipoprotein(a); Male; Prognosis; Risk Factors; Severity of Illness Index; Stroke

2013
Reply to Fang SK--Meta-analysis of B vitamin supplementation on plasma homocysteine, cardiovascular and all-cause mortality.
    Clinical nutrition (Edinburgh, Scotland), 2013, Volume: 32, Issue:2

    Topics: Coronary Disease; Dietary Supplements; Homocysteine; Humans; Myocardial Infarction; Stroke; Vitamin B Complex

2013
Acute phase homocysteine related to severity and outcome of atherothrombotic stroke.
    European journal of internal medicine, 2013, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Cohort Studies; Female; Follow-Up Studies; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prognosis; Prospective Studies; Recurrence; Severity of Illness Index; Stroke; Thrombosis

2013
Homocysteine and cystatin C level changes in haemodialysed patients and connection with cerebro- and cardiovascular complications.
    Acta physiologica Hungarica, 2001, Volume: 88, Issue:3-4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Cystatin C; Cystatins; Diabetes Mellitus, Type 1; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Stroke

2001
An association between plasma homocysteine concentrations and ischemic stroke in elderly Japanese.
    Journal of atherosclerosis and thrombosis, 2002, Volume: 9, Issue:2

    Topics: Age Distribution; Aged; Aged, 80 and over; Arteriosclerosis; Brain Ischemia; Female; Homocysteine; Humans; Japan; Logistic Models; Male; Risk Factors; Rural Population; Stroke

2002
Homocysteine, stroke, and dementia.
    Stroke, 2002, Volume: 33, Issue:10

    Topics: Aging; Alzheimer Disease; Causality; Comorbidity; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Vitamin B Complex

2002
Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland.
    Stroke, 2002, Volume: 33, Issue:10

    Topics: Aged; Alleles; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Comorbidity; Dementia, Vascular; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Northern Ireland; Nutritional Status; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Risk Assessment; Risk Factors; Statistical Distributions; Stroke

2002
Role of homocysteine for thromboembolic complication in patients with non-valvular atrial fibrilation.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2002, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Case-Control Studies; Female; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Stroke; Thromboembolism

2002
Relation between homocysteine and non-fatal stroke in peripheral arterial disease.
    European journal of neurology, 2002, Volume: 9, Issue:6

    Topics: Aged; Arteries; Arteriosclerosis; Forecasting; Homocysteine; Humans; Intracranial Thrombosis; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Peripheral Vascular Diseases; Stroke

2002
Folate delivers head-to-toe health advantages. The B vitamin that benefits unborn babies may also protect the hearts and minds (and colons) of adults.
    Health news (Waltham, Mass.), 2002, Volume: 8, Issue:12

    Topics: Alzheimer Disease; Anencephaly; Colonic Neoplasms; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Male; Pregnancy; Spinal Dysraphism; Stroke

2002
Stroke in young patients with hyperhomocysteinemia due to cystathionine beta-synthase deficiency.
    Neurology, 2003, Jan-28, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Age Factors; Amino Acid Substitution; Cells, Cultured; Cerebral Infarction; Cystathionine beta-Synthase; DNA Mutational Analysis; Female; Fibroblasts; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mutation; Retinal Artery Occlusion; Stroke

2003
Homocysteine, MTHFR 677C-->T polymorphism, and risk of ischemic stroke: results of a meta-analysis.
    Neurology, 2003, Feb-11, Volume: 60, Issue:3

    Topics: Brain Ischemia; Case-Control Studies; Cohort Studies; Data Interpretation, Statistical; Homocysteine; Humans; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Reproducibility of Results; Research Design; Risk Assessment; Stroke

2003
Homocysteine as a risk factor for cognitive impairment in stroke patients.
    Dementia and geriatric cognitive disorders, 2003, Volume: 15, Issue:3

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognition Disorders; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Risk Factors; Stroke

2003
Hyperhomocysteinemia is associated with the presence of left atrial thrombus in stroke patients with nonvalvular atrial fibrillation.
    Stroke, 2003, Volume: 34, Issue:4

    Topics: Aged; Atrial Fibrillation; Echocardiography, Transesophageal; Female; Heart Atria; Heart Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stroke; Thrombosis

2003
Prospective study of serum homocysteine and risk of ischemic stroke among patients with preexisting coronary heart disease.
    Stroke, 2003, Volume: 34, Issue:3

    Topics: Brain Ischemia; Case-Control Studies; Chronic Disease; Cohort Studies; Comorbidity; Coronary Disease; Female; Follow-Up Studies; Homocysteine; Humans; Incidence; Israel; Male; Matched-Pair Analysis; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Odds Ratio; Prospective Studies; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Stroke

2003
[Hyperhomocysteinemia hastens myocardial infarct and stroke. Prevention.with leaf salads and vitamins].
    MMW Fortschritte der Medizin, 2003, Mar-06, Volume: 145, Issue:10

    Topics: Adult; Age Factors; Aged; Arteriosclerosis; Clinical Trials as Topic; Dementia; Diet; Drug Therapy, Combination; Female; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Prospective Studies; Risk Factors; Sex Factors; Stroke; Vegetables; Vitamin B 12; Vitamin B 6

2003
Homocysteine and risk of recurrent stroke.
    Stroke, 2003, Volume: 34, Issue:5

    Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Brain Ischemia; Cerebral Hemorrhage; Comorbidity; Denmark; Diabetes Mellitus; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Ischemic Attack, Transient; Male; Middle Aged; Odds Ratio; Prospective Studies; Recurrence; Risk; Risk Factors; Smoking; Stroke

2003
Low vitamin B6 but not homocyst(e)ine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain fortification.
    Stroke, 2003, Volume: 34, Issue:6

    Topics: Case-Control Studies; Comorbidity; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Homocystine; Humans; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxal Phosphate; Risk Assessment; Risk Factors; Serum Albumin; Stroke; United States; Vitamin B 12; Vitamin B 6

2003
Blood homocysteine levels in stroke patients undergoing rehabilitation.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:6

    Topics: Biomarkers; Brain Damage, Chronic; Female; Functional Laterality; Homocysteine; Humans; Male; Recurrence; Stroke; Stroke Rehabilitation

2003
Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China.
    Stroke, 2003, Volume: 34, Issue:9

    Topics: Brain Ischemia; Case-Control Studies; Cerebral Hemorrhage; China; Comorbidity; DNA Mutational Analysis; Female; Gene Frequency; Genotype; Homocysteine; Humans; Intracranial Thrombosis; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Risk Assessment; Risk Factors; Stroke

2003
Plasma homocysteine level and the course of ischemic stroke.
    Acta neurobiologiae experimentalis, 2003, Volume: 63, Issue:2

    Topics: Aged; Brain Ischemia; Disease Progression; Female; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Prognosis; Risk Factors; Stroke

2003
Homocysteine and the risk of stroke and thromboembolism in atrial fibrillation: an uncertain role.
    Stroke, 2003, Volume: 34, Issue:9

    Topics: Atrial Fibrillation; Causality; Comorbidity; Homocysteine; Humans; Hyperhomocysteinemia; Risk Assessment; Stroke; Thromboembolism

2003
Measuring blood homocysteine levels in stroke patients.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:8

    Topics: Arteriosclerosis; Homocysteine; Humans; Retrospective Studies; Risk Factors; Stroke

2003
Neurological implications of hyperhomocysteinemia in patients with atherothrombotic disease.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2003, Volume: 4, Issue:9

    Topics: Brain Ischemia; Coronary Artery Disease; Coronary Thrombosis; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Risk Factors; Stroke

2003
Further evidence of interrelation between homocysteine and hypertension in stroke patients: a cross-sectional study.
    The Israel Medical Association journal : IMAJ, 2003, Volume: 5, Issue:11

    Topics: Acute Disease; Aged; Aged, 80 and over; Brain Ischemia; Comorbidity; Cross-Sectional Studies; Female; Homocysteine; Humans; Hypertension; Israel; Male; Middle Aged; Odds Ratio; Recurrence; Regression Analysis; Retrospective Studies; Stroke

2003
Inflammation, homocysteine, and vitamin B6 status after ischemic stroke.
    Stroke, 2004, Volume: 35, Issue:1

    Topics: Aged; Brain Ischemia; C-Reactive Protein; Comorbidity; Female; Homocysteine; Humans; Inflammation; Male; Multivariate Analysis; Odds Ratio; Pyridoxal Phosphate; Stroke; Vitamin B 6 Deficiency

2004
Red cell N5-methyltetrahydrofolate concentrations and C677T methylenetetrahydrofolate reductase genotype in patients with stroke.
    Journal of clinical pathology, 2004, Volume: 57, Issue:1

    Topics: Acute Disease; Analysis of Variance; Dietary Supplements; Erythrocytes; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Stroke; Tetrahydrofolates; Vitamins

2004
Hyperhomocysteinemia, oxidative stress, and cerebral vascular dysfunction.
    Stroke, 2004, Volume: 35, Issue:2

    Topics: Arginine; Cerebrovascular Circulation; DNA Methylation; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Reactive Oxygen Species; Risk Factors; Stroke

2004
The challenge of stroke prevention.
    JAMA, 2004, Feb-04, Volume: 291, Issue:5

    Topics: Antibodies, Antiphospholipid; Folic Acid; Homocysteine; Humans; Risk Factors; Risk Reduction Behavior; Stroke; Vitamin B 12; Vitamin B 6

2004
Mild hyperhomocysteinemia is a risk-factor in all etiological subtypes of stroke.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2004, Volume: 25, Issue:1

    Topics: Aged; Chromatography, High Pressure Liquid; Diabetes Complications; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Male; Risk Factors; Smoking; Stroke

2004
Young stroke and basal plasma and post-methionine load homocysteine and cysteine levels 1 year after the acute event: do plasma folates make the difference?
    European journal of neurology, 2004, Volume: 11, Issue:4

    Topics: Adult; Case-Control Studies; Cysteine; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Middle Aged; Stroke; Time Factors; Vitamin B 12

2004
Secondary prevention for stroke and transient ischaemic attacks: Horizons needs expanding.
    BMJ (Clinical research ed.), 2004, Apr-10, Volume: 328, Issue:7444

    Topics: Blood Glucose; Homocysteine; Humans; Ischemic Attack, Transient; Risk Factors; Stroke

2004
Relationship of homocysteine to markers of platelet and endothelial activation in "high risk" hypertensives: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial.
    International journal of cardiology, 2004, Volume: 94, Issue:2-3

    Topics: Aged; Biomarkers; Clinical Trials as Topic; Coronary Disease; Cross-Sectional Studies; Endothelium, Vascular; Female; Fibrinogen; Homocysteine; Humans; Hypertension; Male; Middle Aged; Outcome Assessment, Health Care; P-Selectin; Platelet Activation; Risk Factors; Stroke; von Willebrand Factor

2004
Hyperhomocysteinaemia in a young woman presenting with stroke, associated with methylene tetrahydrofolate reductase C677T homozygosity.
    Annals of clinical biochemistry, 2004, Volume: 41, Issue:Pt 3

    Topics: Adult; Brain Ischemia; Contraceptives, Oral; Female; Genotype; Heart Septal Defects, Atrial; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Risk Factors; Stroke

2004
Autoantibodies against N-homocysteinylated proteins in humans: implications for atherosclerosis.
    Stroke, 2004, Volume: 35, Issue:6

    Topics: Aged; Arteriosclerosis; Autoantibodies; Blood Proteins; Epitopes; Female; Homocysteine; Humans; Immunoglobulin G; Lysine; Male; Middle Aged; Stroke

2004
VISP and INVEST.
    Preventive cardiology, 2004,Spring, Volume: 7, Issue:2

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Coronary Disease; Homocysteine; Humans; Hypertension; Indoles; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Stroke; Verapamil; Vitamins

2004
Vitamin supplementation and risk of stroke.
    JAMA, 2004, May-12, Volume: 291, Issue:18

    Topics: Homocysteine; Humans; Risk; Stroke; Vitamins

2004
Vitamin supplementation and risk of stroke.
    JAMA, 2004, May-12, Volume: 291, Issue:18

    Topics: Homocysteine; Humans; Risk Reduction Behavior; Stroke; Vitamins

2004
Serum total homocysteine concentrations and risk of stroke and its subtypes in Japanese.
    Circulation, 2004, Jun-08, Volume: 109, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Brain Infarction; Brain Ischemia; Case-Control Studies; Female; Homocysteine; Humans; Incidence; Intracranial Hemorrhages; Japan; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Factors; Stroke

2004
Various forms of homocysteine and oxidative status in the plasma of ischemic-stroke patients as compared to healthy controls.
    Clinical biochemistry, 2004, Volume: 37, Issue:6

    Topics: Aged; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Oxidative Stress; Retrospective Studies; Stroke

2004
Plasma homocysteine levels and risk of Alzheimer disease.
    Neurology, 2004, Jun-08, Volume: 62, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Comorbidity; Confounding Factors, Epidemiologic; Cross-Sectional Studies; Cysteine; Dementia; Diabetes Mellitus; Ethnicity; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Neuropsychological Tests; New York City; Prevalence; Risk Factors; Sampling Studies; Stroke; Vitamin B 12; Vitamin B 6

2004
Homocysteine, vitamin B6, and endothelial dysfunction in circulatory disorders.
    Stroke, 2004, Volume: 35, Issue:8

    Topics: Arginine; C-Reactive Protein; Endothelium, Vascular; Homocysteine; Humans; Nitric Oxide; Pyridoxal Phosphate; Stroke; Vitamin B 6; Vitamin B 6 Deficiency

2004
Folic acid-based multivitamin therapy to prevent stroke: the jury is still out.
    Stroke, 2004, Volume: 35, Issue:8

    Topics: Clinical Trials as Topic; Dietary Supplements; Folic Acid; Homocysteine; Humans; Risk; Stroke

2004
Homocysteine and cardiovascular disease: a 17-year follow-up study in Busselton.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2004, Volume: 11, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Australia; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Confounding Factors, Epidemiologic; Coronary Disease; Creatinine; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Prospective Studies; Risk Factors; Sex Factors; Stroke

2004
New advances in identifying genetic anomalies in stroke-prone probands.
    Current neurology and neuroscience reports, 2004, Volume: 4, Issue:5

    Topics: Anemia, Sickle Cell; Arteriosclerosis; Dementia, Multi-Infarct; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Homocysteine; Humans; Lipid Metabolism; Lipoproteins; MELAS Syndrome; Mutation; Polymorphism, Genetic; Stroke

2004
Homocysteine and the risk of ischemic stroke in a triethnic cohort: the NOrthern MAnhattan Study.
    Stroke, 2004, Volume: 35, Issue:10

    Topics: Aged; Black People; Cohort Studies; Female; Hispanic or Latino; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Vascular Diseases; White People

2004
Relationship between homocysteine and cardiovascular diseases in older adults.
    Journal of the American Geriatrics Society, 2004, Volume: 52, Issue:11

    Topics: Adult; Aged; Cardiovascular Diseases; Female; Homocysteine; Humans; Male; Middle Aged; Myocardial Ischemia; Risk Factors; Stroke

2004
Spontaneous cervical artery dissections and implications for homocysteine.
    Journal of manipulative and physiological therapeutics, 2004, Volume: 27, Issue:8

    Topics: Homocysteine; Humans; Manipulation, Chiropractic; Risk Factors; Stroke; Vertebral Artery Dissection

2004
Homocysteine, cerebrovascular disease and brain atrophy.
    Journal of the neurological sciences, 2004, Nov-15, Volume: 226, Issue:1-2

    Topics: Aged; Aged, 80 and over; Atrophy; Brain; Cerebral Infarction; Cerebrovascular Disorders; Cognition; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Randomized Controlled Trials as Topic; Stroke

2004
Methylenetetrahydrofolate reductase gene A222V polymorphism and risk of ischemic stroke.
    Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:12

    Topics: Age Distribution; Aged; Aged, 80 and over; Alleles; Brain Ischemia; Case-Control Studies; Cohort Studies; Female; Genotype; Homocysteine; Hong Kong; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Genetic; Risk Factors; Sex Distribution; Sex Factors; Stroke

2004
MTHFR C677T gene mutation as a risk factor for arterial stroke: a hospital based study.
    European journal of neurology, 2005, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Cerebral Arterial Diseases; Child; Cytosine; Female; Genetic Carrier Screening; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Risk Factors; Stroke; Thymine

2005
Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke.
    Neurology, 2004, Dec-28, Volume: 63, Issue:12

    Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Cholesterol; Dementia, Vascular; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germany; Glutathione Transferase; Homocysteine; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Point Mutation; Polymorphism, Genetic; Stroke

2004
Folate deficiency increases postischemic brain injury.
    Stroke, 2005, Volume: 36, Issue:2

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Colorimetry; DNA Damage; Folic Acid; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Infarction, Middle Cerebral Artery; Mice; Mice, Transgenic; Oxygen; Reperfusion; Reperfusion Injury; Risk; Stroke; Time Factors; Uracil-DNA Glycosidase

2005
[Genetic mutations of homocysteine metabolism related enzymes in patients with ischemic stroke].
    Yi chuan = Hereditas, 2004, Volume: 26, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cystathionine beta-Synthase; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Stroke

2004
Plasma homocysteine level and functional outcome of patients with ischemic stroke.
    Archives of physical medicine and rehabilitation, 2005, Volume: 86, Issue:1

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Brain Ischemia; Disability Evaluation; Female; Homocysteine; Humans; Male; Middle Aged; Patient Admission; Patient Discharge; Predictive Value of Tests; Recovery of Function; Retrospective Studies; Stroke; Stroke Rehabilitation

2005
Serum lipid profiles and homocysteine levels in adults with stroke or myocardial infarction in the town of Gombe in northern Nigeria.
    Journal of health, population, and nutrition, 2004, Volume: 22, Issue:4

    Topics: Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Female; Folic Acid; Homocysteine; Humans; Hypertension; Lipids; Male; Middle Aged; Myocardial Infarction; Nigeria; Risk Factors; Stroke; Triglycerides; Vitamin B 12

2004
Stroke and recurrent pregnancy loss due to hyperhomocysteinaemia.
    European journal of neurology, 2005, Volume: 12, Issue:3

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Abortion, Habitual; Brain; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Infarction, Middle Cerebral Artery; Middle Aged; Mutation; Platelet Aggregation Inhibitors; Pregnancy; Stroke; Treatment Outcome; Vitamin B 12

2005
Homocysteine and fracture prevention.
    JAMA, 2005, Mar-02, Volume: 293, Issue:9

    Topics: Dietary Supplements; Folic Acid; Hip Fractures; Homocysteine; Humans; Risk Factors; Stroke; Vitamin B 12

2005
[A case-control study on the relationship between stroke and plasma homocysteine level and the mutation of MTHFR gene].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2004, Volume: 25, Issue:11

    Topics: Case-Control Studies; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Stroke

2004
Homocysteine as a predictive factor for hip fracture in stroke patients.
    Bone, 2005, Volume: 36, Issue:4

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Bone Density; Female; Hip Fractures; Homocysteine; Humans; Male; Risk Factors; Stroke

2005
[Association between plasmatic levels of homocysteine and stroke: a transversal analytic study].
    Arquivos de neuro-psiquiatria, 2005, Volume: 63, Issue:1

    Topics: Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Epidemiologic Methods; Female; Homocysteine; Humans; Male; Middle Aged; Stroke

2005
Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study.
    Stroke, 2005, Volume: 36, Issue:6

    Topics: Aged; Brain; Disease Progression; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; New York; Risk Factors; Social Class; Stroke; Vitamin B 12 Deficiency

2005
Folate, vitamin B12, and risk of ischemic and hemorrhagic stroke: a prospective, nested case-referent study of plasma concentrations and dietary intake.
    Stroke, 2005, Volume: 36, Issue:7

    Topics: Adult; Aged; Brain Ischemia; Case-Control Studies; Cohort Studies; Diet; Female; Folic Acid; Hemorrhage; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Nutritional Status; Odds Ratio; Polymorphism, Genetic; Prospective Studies; Registries; Risk; Stroke; Sweden; Vitamin B 12

2005
[Hyperhomocysteinemia. Causal risk factors for stroke].
    Medizinische Monatsschrift fur Pharmazeuten, 2005, Volume: 28, Issue:7

    Topics: Cohort Studies; Homocysteine; Humans; Random Allocation; Risk Factors; Stroke

2005
Common genetic variants of homocysteine metabolism in ischemic stroke: a case-control study.
    European journal of neurology, 2005, Volume: 12, Issue:8

    Topics: Adult; Age Factors; Aged; Case-Control Studies; Confidence Intervals; DNA Mutational Analysis; Female; Gene Frequency; Genetic Variation; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stroke

2005
Serum homocysteine, folate and risk of stroke: Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2005, Volume: 12, Issue:4

    Topics: Age Factors; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Finland; Folic Acid; Follow-Up Studies; Hematinics; Homocysteine; Humans; Male; Middle Aged; Myocardial Ischemia; Odds Ratio; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Triglycerides

2005
Vitamin therapy may reduce hip fracture risk. Folate, B12 appear to reduce homocysteine levels.
    Health news (Waltham, Mass.), 2005, Volume: 11, Issue:6

    Topics: Aged; Female; Folic Acid; Hip Fractures; Homocysteine; Humans; Male; Stroke; Vitamin B 12

2005
The association between hyperhomocysteinemia and ischemic stroke in patients with non-valvular atrial fibrillation.
    Haematologica, 2005, Volume: 90, Issue:9

    Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Stroke

2005
Culprit factors for the failure of well-conducted warfarin therapy to prevent ischemic events in patients with atrial fibrillation: the role of homocysteine.
    Stroke, 2005, Volume: 36, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Echocardiography; Female; Follow-Up Studies; Homocysteine; Humans; Ischemia; Male; Middle Aged; Models, Statistical; Multivariate Analysis; Odds Ratio; Prospective Studies; Regression Analysis; Research Design; Risk; Risk Factors; Stroke; Time Factors; Treatment Failure; Treatment Outcome; Warfarin

2005
Thrombophilias and stroke: diagnosis, treatment, and prognosis.
    Journal of thrombosis and thrombolysis, 2005, Volume: 20, Issue:2

    Topics: Anticoagulants; Cystathionine beta-Synthase; Factor V; Genetic Predisposition to Disease; Genetic Testing; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Methylenetetrahydrofolate Reductase (NADPH2); Platelet Activation; Platelet Aggregation; Polymorphism, Genetic; Prognosis; Protein S Deficiency; Prothrombin; Secondary Prevention; Stroke; Thrombophilia; Warfarin

2005
"Brain Screen": A self-referral, screening program for strokes, falls and dementia risk factors.
    Journal of neurology, 2006, Volume: 253, Issue:3

    Topics: Accidental Falls; Adult; Aged; Aged, 80 and over; Cholesterol; Dementia; Female; Homocysteine; Humans; Male; Mass Screening; Middle Aged; Neuropsychological Tests; Referral and Consultation; Risk Factors; Stroke

2006
[Assessment of metabolic atherosclerosis risk factors in progeny of patients with past ischemic stroke].
    Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 113, Issue:2

    Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Biomarkers; Brain Ischemia; C-Reactive Protein; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Female; Fibrinogen; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Life Style; Lipoprotein(a); Male; Risk Factors; Stroke; Time Factors; Triglycerides; von Willebrand Factor

2005
Vitamin Intervention For Stroke Prevention trial: an efficacy analysis.
    Stroke, 2005, Volume: 36, Issue:11

    Topics: Aged; Disease-Free Survival; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Ischemia; Male; Middle Aged; Models, Statistical; Randomized Controlled Trials as Topic; Stroke; Time Factors; Treatment Outcome; Vitamin B 12; Vitamins

2005
Plasma total homocysteine levels in stroke patients screened for the vitamin intervention for stroke prevention clinical trial in the era of folate fortification.
    Neuroepidemiology, 2006, Volume: 26, Issue:1

    Topics: Adult; Aged; Canada; Fasting; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Middle Aged; Reproducibility of Results; Stroke; United States; Vitamins

2006
Hyperhomocysteinemia is associated with volumetric white matter change in patients with small vessel disease.
    Journal of neurology, 2006, Volume: 253, Issue:4

    Topics: Aged; Brain; Cerebrovascular Disorders; Cognition Disorders; Cohort Studies; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychometrics; Regression Analysis; Risk Factors; Stroke; Vitamin B 12

2006
Pediatric stroke and methylenetetrahydrofolate reductase polymorphisms: an examination of C677T and A1298C mutations.
    Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:11

    Topics: Child; Child, Preschool; Female; Homocysteine; Homozygote; Humans; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Genetic; Retrospective Studies; Stroke

2005
B vitamins and homocysteine.
    Harvard health letter, 2005, Volume: 30, Issue:12

    Topics: Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B 12; Vitamin B 6

2005
Elevated plasma homocysteine in acute stroke was not associated with severity and outcome: stronger association with small artery disease.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2005, Volume: 26, Issue:5

    Topics: Adult; Aged; Case-Control Studies; Cerebral Arterial Diseases; Female; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Regression Analysis; Risk Factors; Severity of Illness Index; Stroke

2005
Homocysteine: call off the funeral.
    Stroke, 2006, Volume: 37, Issue:2

    Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Stroke; Vitamin B 12

2006
Serum level of homocysteine is correlated to carotid artery atherosclerosis in Chinese with ischemic stroke.
    Neurological research, 2006, Volume: 28, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Asian People; Biomarkers; Carotid Artery Diseases; Carotid Artery, Common; Carotid Artery, Internal; Carotid Stenosis; Female; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Retrospective Studies; Statistics, Nonparametric; Stroke; Ultrasonography

2006
Improvement in stroke mortality in Canada and the United States, 1990 to 2002.
    Circulation, 2006, Mar-14, Volume: 113, Issue:10

    Topics: Adult; Age Distribution; Aged; Canada; Edible Grain; England; Folic Acid; Food, Fortified; Homocysteine; Humans; Linear Models; Middle Aged; Racial Groups; Risk Factors; Sex Factors; Stroke; United States; Wales

2006
Mutations and polymorphisms in genes affecting hemostasis proteins and homocysteine metabolism in children with arterial ischemic stroke.
    Cerebrovascular diseases (Basel, Switzerland), 2006, Volume: 22, Issue:1

    Topics: Alleles; Brain Ischemia; Child, Preschool; DNA; Factor V; Female; Genotype; Hemostasis; Homocysteine; Humans; Infant; Infant, Newborn; Male; Mutation; Odds Ratio; Polymorphism, Genetic; Risk Factors; Stroke

2006
Plasma total homocysteine levels are associated with advanced leukoaraiosis but not with asymptomatic microbleeds on T2*-weighted MRI in patients with stroke.
    European journal of neurology, 2006, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Intracranial Hemorrhages; Leukoaraiosis; Logistic Models; Magnetic Resonance Imaging; Male; Stroke

2006
Acute stroke in relation to homocysteine and methylenetetrahydrofolate reductase gene polymorphisms.
    Acta neurologica Scandinavica, 2006, Volume: 113, Issue:5

    Topics: Case-Control Studies; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Stroke

2006
Folate supplementation and cardiovascular disease.
    Lancet (London, England), 2006, Apr-15, Volume: 367, Issue:9518

    Topics: Cardiovascular Diseases; Folic Acid; Hematinics; Homocysteine; Humans; Randomized Controlled Trials as Topic; Stroke; Vitamin B 12; Vitamin B 6

2006
Role of MTHFR C677T polymorphism in ischemic stroke.
    Neurology India, 2006, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Brain Ischemia; Child; Child, Preschool; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Stroke

2006
[Better prognosis for stroke patients].
    MMW Fortschritte der Medizin, 2006, May-18, Volume: 148, Issue:20

    Topics: Aged, 80 and over; Bias; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Stroke; Vitamin B 12; Vitamin B 6

2006
The relationship between homocysteine, cognition and stroke subtypes in acute stroke.
    Journal of the neurological sciences, 2006, Dec-01, Volume: 250, Issue:1-2

    Topics: Acute Disease; Aged; Brain; Brain Infarction; Cerebral Arteries; Cerebrovascular Circulation; Cognition; Cognition Disorders; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Predictive Value of Tests; Statistics as Topic; Stroke; Up-Regulation

2006
Methylenetetrahydrofolate reductase gene polymorphism in Indian stroke patients.
    Neurology India, 2006, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Aged; Blotting, Northern; Chi-Square Distribution; Child; Child, Preschool; DNA Mutational Analysis; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Stroke; Vitamin B 12

2006
Pediatric stroke, homocysteine and MTHFR 677C-T and 1298 A-C.
    Journal of pediatric hematology/oncology, 2006, Volume: 28, Issue:9

    Topics: Age Factors; Child; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Genetic; Risk Factors; Stroke

2006
Homocysteine and outcome in young patients with acute coronary syndromes.
    International journal of cardiology, 2007, May-31, Volume: 118, Issue:2

    Topics: Age Factors; Cohort Studies; Comorbidity; Female; Follow-Up Studies; Homocysteine; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Prognosis; Proportional Hazards Models; Prospective Studies; Recurrence; Risk Factors; Sex Distribution; Spain; Stroke; Survival Analysis

2007
Association of cardiovascular risk factors and disease with depression in later life.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2007, Volume: 15, Issue:6

    Topics: Age of Onset; Aged; Aged, 80 and over; Angina Pectoris; Cardiovascular Diseases; Cross-Sectional Studies; Depressive Disorder, Major; Diabetes Mellitus, Type 2; Homocysteine; Humans; Male; Myocardial Infarction; Risk Factors; Stroke; Surveys and Questionnaires; Triglycerides

2007
Serial measurements of plasma homocysteine levels in early and late phases of ischemic stroke.
    European journal of neurology, 2007, Volume: 14, Issue:1

    Topics: Aged; Biomarkers; Brain Ischemia; Case-Control Studies; Female; Follow-Up Studies; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Research Design; Stroke; Time Factors

2007
Both vitamin B6 and total homocysteine plasma levels predict long-term atherothrombotic events in healthy subjects.
    European heart journal, 2007, Volume: 28, Issue:4

    Topics: Adult; C-Reactive Protein; Case-Control Studies; Coronary Artery Disease; Coronary Thrombosis; Female; Homocysteine; Humans; Intracranial Arteriosclerosis; Intracranial Thrombosis; Male; Middle Aged; Prospective Studies; Risk Factors; Stroke; Vitamin B 6

2007
Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; California; Cognition Disorders; Dementia; Disease Susceptibility; Female; Folic Acid; Health Surveys; Hispanic or Latino; Homocysteine; Humans; Incidence; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12

2007
[Neurological syndromes associated with homocystein dismetabolism].
    Klinicheskaia meditsina, 2006, Volume: 84, Issue:12

    Topics: Demyelinating Diseases; Diagnosis, Differential; Disease Progression; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Leukoencephalitis, Acute Hemorrhagic; Magnetic Resonance Imaging; Male; Middle Aged; Polyneuropathies; Prognosis; Risk Factors; Stroke

2006
Influence of MTHFR genotype on contingent negative variation and MRI abnormalities in migraine.
    Headache, 2007, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Case-Control Studies; Contingent Negative Variation; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Homozygote; Humans; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Migraine Disorders; Risk Factors; Stroke

2007
Association of vitamin B12, folate and homocysteine with functional and pathological characteristics of the elderly in a mountainous village in Sicily.
    Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Diabetes Mellitus; Folic Acid; Homocysteine; Humans; Middle Aged; Neoplasms; Peripheral Vascular Diseases; Sicily; Stroke; Vitamin B 12

2007
Homocysteine and post-stroke cognitive decline.
    Age and ageing, 2007, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Attention; Cognition; Cognition Disorders; Cohort Studies; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Logistic Models; Predictive Value of Tests; Recovery of Function; Stroke; Time Factors; Verbal Behavior

2007
Influence of combined methionine synthase (MTR 2756A > G) and methylenetetrahydrofolate reductase (MTHFR 677C > T) polymorphisms to plasma homocysteine levels in Korean patients with ischemic stroke.
    Yonsei medical journal, 2007, Apr-30, Volume: 48, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; DNA; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Stroke

2007
Homocysteinemia may be equally important to stroke subtype in predicting cognition impairment.
    Journal of the neurological sciences, 2007, Sep-15, Volume: 260, Issue:1-2

    Topics: Biomarkers; Cerebral Arteries; Cerebrovascular Disorders; Cognition Disorders; Homocysteine; Homocystinuria; Humans; Models, Neurological; Predictive Value of Tests; Regression Analysis; Risk Factors; Stroke

2007
Lowering homocysteine for stroke prevention.
    Lancet (London, England), 2007, Jun-02, Volume: 369, Issue:9576

    Topics: Folic Acid; Homocysteine; Humans; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Stroke; Vitamin B Complex

2007
Plasma total homocysteine in acute stroke.
    European journal of neurology, 2007, Volume: 14, Issue:7

    Topics: Acute Disease; Artifacts; Blood Viscosity; Cholesterol; Homocysteine; Humans; Lipids; Osmolar Concentration; Posture; Stroke

2007
The serum high-sensitive C reactive protein and homocysteine levels to evaluate the prognosis of acute ischemic stroke.
    Mediators of inflammation, 2007, Volume: 2007

    Topics: Acute Disease; Aged; Aged, 80 and over; Brain Ischemia; C-Reactive Protein; Case-Control Studies; Homocysteine; Humans; Middle Aged; Prognosis; Stroke; Time Factors

2007
Plasma homocysteine and ischemic stroke patients in Thailand.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2007, Volume: 90, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stroke; Thailand

2007
Correlations between folate, B12, homocysteine levels, and radiological markers of neuropathology in elderly post-stroke patients.
    Journal of the American College of Nutrition, 2007, Volume: 26, Issue:3

    Topics: Aged; Biomarkers; Brain; Brain Infarction; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mental Recall; Nutrition Assessment; Nutrition Policy; Stroke; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex

2007
Response to Dr Spence: Plasma total homocysteine in acute stroke.
    European journal of neurology, 2007, Volume: 14, Issue:8

    Topics: Artifacts; Bed Rest; Blood Viscosity; Blood Volume; Hematocrit; Homocysteine; Humans; Lipids; Posture; Stroke

2007
Aortic arch atheroma progression and recurrent vascular events in patients with stroke or transient ischemic attack.
    Circulation, 2007, Aug-21, Volume: 116, Issue:8

    Topics: Aged; Aorta, Thoracic; Atherosclerosis; Disease Progression; Disease-Free Survival; Echocardiography, Transesophageal; Female; Follow-Up Studies; Homocysteine; Humans; Hypertension; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Middle Aged; Prevalence; Recurrence; Risk Factors; Stroke

2007
Is homocysteine a causal and treatable risk factor for stroke?
    The Lancet. Neurology, 2007, Volume: 6, Issue:9

    Topics: Homocysteine; Humans; Risk Factors; Stroke; Vitamins

2007
Folic acid for stroke prevention.
    Lancet (London, England), 2007, Aug-25, Volume: 370, Issue:9588

    Topics: Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Research Design; Risk; Stroke; Vitamin B Complex

2007
Acute multiple brain infarction in large-artery atherosclerosis is associated with hyperhomocyst(e)inemia.
    Acta neurologica Scandinavica, 2007, Volume: 116, Issue:4

    Topics: Aged; Aged, 80 and over; Brain Infarction; Cohort Studies; Diffusion Magnetic Resonance Imaging; Female; Homocysteine; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Risk Factors; Stroke

2007
The paraoxonase gene polymorphism in stroke patients and lipid profile.
    Acta neurologica Scandinavica, 2008, Volume: 117, Issue:4

    Topics: Aged; Apolipoproteins B; Aryldialkylphosphatase; Brain Ischemia; Cholesterol, LDL; DNA Mutational Analysis; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Intracranial Arteriosclerosis; Lipid Metabolism; Male; Middle Aged; Polymorphism, Genetic; Stroke

2008
The effect of polymorphisms of MTHFR C677T, A1298C, MS A2756G and CBS 844ins68bp on plasma total homocysteine level and the risk of ischemic stroke in Thai children.
    Thrombosis research, 2008, Volume: 122, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Gene Frequency; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Insertional; Polymorphism, Single Nucleotide; Reference Values; Stroke; Thailand

2008
Association of diabetes, homocysteine, and HDL with cognition and disability after stroke.
    Neurology, 2007, Nov-27, Volume: 69, Issue:22

    Topics: Aged; Brief Psychiatric Rating Scale; Cholesterol, HDL; Cognition; Cognition Disorders; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Stroke

2007
Serum total homocysteine concentrations and risk of mortality from stroke and coronary heart disease in Japanese: The JACC study.
    Atherosclerosis, 2008, Volume: 198, Issue:2

    Topics: Adult; Aged; Asian People; Coronary Disease; Female; Follow-Up Studies; Homocysteine; Humans; Japan; Male; Middle Aged; Risk; Stroke

2008
Determinants and associations of homocysteine and prothrombotic risk factors in Kuwaiti patients with cerebrovascular accident.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2008, Volume: 17, Issue:2

    Topics: Adult; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kuwait; Logistic Models; Male; Middle Aged; Risk Factors; Stroke; Thrombophilia

2008
Asymmetric dimethylarginine independently predicts fatal and nonfatal myocardial infarction and stroke in women: 24-year follow-up of the population study of women in Gothenburg.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:5

    Topics: Adult; Arginine; Biomarkers; Cohort Studies; Female; Follow-Up Studies; Homocysteine; Humans; Longitudinal Studies; Middle Aged; Myocardial Infarction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Sweden

2008
Extracellular magnesium regulates effects of vitamin B6, B12 and folate on homocysteinemia-induced depletion of intracellular free magnesium ions in canine cerebral vascular smooth muscle cells: possible relationship to [Ca2+]i, atherogenesis and stroke.
    Neuroscience letters, 1999, Oct-22, Volume: 274, Issue:2

    Topics: Animals; Arteriosclerosis; Basilar Artery; Calcium; Cells, Cultured; Cerebral Arteries; Dogs; Folic Acid; Homocysteine; Hyperhomocysteinemia; Magnesium; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Pyridoxine; Signal Transduction; Stroke; Vitamin B 12; Vitamins

1999
[Plasma homocysteine as a risk factor for apoplexy].
    Ugeskrift for laeger, 2000, Jan-24, Volume: 162, Issue:4

    Topics: Folic Acid; Homocysteine; Humans; Risk Factors; Stroke

2000
The relation of plasma total homocysteine levels to prevalent cardiovascular disease in older patients with ischemic stroke.
    Aging (Milan, Italy), 2000, Volume: 12, Issue:1

    Topics: Age Distribution; Aged; Brain Ischemia; Cardiovascular Diseases; Female; Homocysteine; Humans; Male; Middle Aged; Reference Values; Retrospective Studies; Sex Distribution; Stroke

2000
Association between high homocyst(e)ine and ischemic stroke due to large- and small-artery disease but not other etiologic subtypes of ischemic stroke.
    Stroke, 2000, Volume: 31, Issue:5

    Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Biomarkers; Brain Ischemia; Female; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Stroke

2000
Redox status of plasma homocysteine and other plasma thiols in stroke patients.
    Atherosclerosis, 2000, Volume: 151, Issue:2

    Topics: Aged; Cysteine; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Osmolar Concentration; Oxidation-Reduction; Reference Values; Stroke; Sulfhydryl Compounds

2000
Distribution and correlates of elevated total homocyst(e)ine: the Stroke Prevention in Young Women Study.
    Annals of epidemiology, 1999, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Biomarkers; Black People; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Logistic Models; Premenopause; Risk Factors; Stroke; United States; White People

1999
Red wine, spirits, beer and serum homocysteine.
    Lancet (London, England), 2000, Aug-05, Volume: 356, Issue:9228

    Topics: Alcohol Drinking; Alcoholic Beverages; Alcoholism; Beer; Cardiovascular Diseases; Homocysteine; Humans; Pyridoxine; Risk Factors; Stroke; Wine

2000
Serum total homocysteine concentration is related to self-reported heart attack or stroke history among men and women in the NHANES III.
    The Journal of nutrition, 2000, Volume: 130, Issue:12

    Topics: Adult; Age Factors; Aged; Female; Folic Acid; Heart Arrest; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutrition Surveys; Risk Factors; Self Disclosure; Sex Factors; Stroke; Vitamin B 12

2000
Homocysteine and ischaemic stroke in men: the Caerphilly study.
    Journal of epidemiology and community health, 2001, Volume: 55, Issue:2

    Topics: Aged; Biomarkers; Cohort Studies; Homocysteine; Humans; Male; Middle Aged; Prognosis; Prospective Studies; Risk Factors; Stroke; Wales

2001
Serum homocysteine and stroke in atrial fibrillation.
    Annals of internal medicine, 2001, Feb-06, Volume: 134, Issue:3

    Topics: Atrial Fibrillation; Homocysteine; Humans; Risk Factors; Stroke

2001
High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease.
    Circulation, 2001, Apr-03, Volume: 103, Issue:13

    Topics: Algorithms; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Circadian Rhythm; Clinical Trials as Topic; Cohort Studies; Europe; Evaluation Studies as Topic; Female; Homocysteine; Hormone Replacement Therapy; Humans; Inflammation; Lipoprotein(a); Male; Middle Aged; Myocardial Infarction; Obesity; Predictive Value of Tests; Prospective Studies; Risk Assessment; Sensitivity and Specificity; Smoking; Stroke; United States

2001
Homozygous thermolabile variant of the methylenetetrahydrofolate reductase gene: a potential risk factor for hyperhomocysteinaemia, CVD, and stroke in childhood.
    Developmental medicine and child neurology, 2001, Volume: 43, Issue:4

    Topics: Adolescent; Alleles; Cerebrovascular Disorders; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Infant; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Recurrence; Risk Factors; Stroke; Temperature

2001
Novel approach for the determination of the redox status of homocysteine and other aminothiols in plasma from healthy subjects and patients with ischemic stroke.
    Clinical chemistry, 2001, Volume: 47, Issue:6

    Topics: Adult; Analysis of Variance; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Ischemia; Male; Oxidation-Reduction; Stroke

2001
Homozygous VN (677C to T) and d/D (2756G to A) variants in the methylenetetrahydrofolate and methionine synthase genes in a case of hyperhomocysteinemia with stroke at young age.
    Experimental & molecular medicine, 2001, Jun-30, Volume: 33, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; DNA; DNA Restriction Enzymes; Family Health; Female; Genetic Variation; Genotype; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Polymorphism, Genetic; Stroke; Tetrahydrofolates

2001
Elevated levels of plasma homocyst(e)ine and asymmetric dimethylarginine in elderly patients with stroke.
    Atherosclerosis, 2001, Volume: 158, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Cerebral Infarction; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Female; Homocysteine; Humans; Logistic Models; Male; Nitric Oxide Synthase; Recurrence; Risk Factors; Stroke

2001
Hyperhomocysteinemia and other inherited prothrombotic conditions in young adults with a history of ischemic stroke.
    Stroke, 2002, Volume: 33, Issue:1

    Topics: Adult; Brain Ischemia; Factor V; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prothrombin; Risk Factors; Stroke; Venous Thrombosis

2002
Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke.
    Stroke, 2002, Volume: 33, Issue:3

    Topics: Adult; Amino Acid Substitution; Brain Ischemia; Carotid Artery, Internal, Dissection; Case-Control Studies; Comorbidity; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Prospective Studies; Reference Values; Risk Factors; Stroke; Vertebral Artery Dissection

2002
Multiple panel of biomarkers for TIA/stroke evaluation.
    Stroke, 2002, Volume: 33, Issue:5

    Topics: Adult; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Autoantibodies; Biomarkers; Diagnosis, Differential; Disease Progression; Female; Glutamic Acid; Glycine; Homocysteine; Humans; Hypertension; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Neuroprotective Agents; Predictive Value of Tests; Receptors, N-Methyl-D-Aspartate; Stroke; Tomography, X-Ray Computed

2002
Homocysteine, vitamin B6, and vascular disease in AD patients.
    Neurology, 2002, May-28, Volume: 58, Issue:10

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Angina Pectoris; Brain Infarction; Coronary Disease; Female; Heart Failure; Homocysteine; Humans; Ischemic Attack, Transient; Male; Myocardial Infarction; Odds Ratio; Pyridoxal Phosphate; Stroke; Vascular Diseases; Vitamin B 6

2002
Inflammation-sensitive proteins: another ingredient in stroke?
    Circulation, 2002, Jun-04, Volume: 105, Issue:22

    Topics: Blood Pressure; Blood Proteins; Brain Diseases; Feeding Behavior; Fruit; Heart Diseases; Homocysteine; Humans; Hypercholesterolemia; Inflammation; Male; Neoplasms; Predictive Value of Tests; Risk; Stroke; Vegetables

2002
Homocysteine, folate, methylene tetrahydrofolate reductase genotype and vascular morbidity in diabetic subjects.
    Clinical science (London, England : 1979), 2002, Volume: 102, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Coronary Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Stroke

2002
Lp(a), homocysteine and a family history of early ischemic cerebral stroke.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2001, Volume: 11 Suppl 5

    Topics: Adolescent; Adult; Brain Ischemia; Factor VII; Female; Fibrinogen; Genetic Predisposition to Disease; Homocysteine; Humans; Lipoprotein(a); Male; Middle Aged; Regression Analysis; Risk Factors; Severity of Illness Index; Stroke; Uric Acid

2001