homocysteine has been researched along with Pregnancy in 820 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (1.46) | 18.7374 |
| 1990's | 82 (10.00) | 18.2507 |
| 2000's | 348 (42.44) | 29.6817 |
| 2010's | 288 (35.12) | 24.3611 |
| 2020's | 90 (10.98) | 2.80 |
| Authors | Studies |
|---|---|
| de Rijke, YB; Felix, JF; Gaillard, R; Heil, SG; Jaddoe, VWV; Monasso, GS | 1 |
| De Rijke, YB; Hoek, J; Mulders, AGMGJ; Reijnders, IF; Ringelberg, B; Schoenmakers, S; Steegers-Theunissen, RPM; Willemsen, SP | 1 |
| Eussen, SJPM; Mommers, M; Obeid, R; Smits, L; Thijs, C | 1 |
| Blaznik, U; Gregorič, M; Gregorič, N; Hribar, M; Hristov, H; Kušar, A; Kvarantan, N; Lavriša, Ž; Oblak, A; Osredkar, J; Pravst, I; Seljak, BK; Zaletel, K; Žmitek, K | 1 |
| Cirillo, M; Coccia, ME; Fatini, C; Fucci, R; Rubini, S | 1 |
| Bharadwaj, B; Dhiman, P; Rajendiran, S; Veena, P | 1 |
| Kim, R; Nijhout, HF; Reed, MC | 1 |
| Bridle, TG; Doroudian, M; Gailer, J; White, W | 1 |
| Balash, L; Gaiday, A; Tussupkaliyev, A | 1 |
| Corsi, DJ; Guo, Y; Luo, R; Retnakaran, R; Rodger, M; Smith, G; Walker, M; Wen, SW; White, RR | 1 |
| Deng, Z; Fu, C; Hu, X; Jing, J; Lu, X; Qin, W; Wang, J | 1 |
| Cao, C; Chen, H; Chen, X; Dou, Y; Huang, G; Huang, X; Jiang, Y; Li, M; Ma, X; Sheng, W; Wang, D; Wang, Y; Yan, W; Zhang, Y | 1 |
| Barbosa, CP; Bianco, B; Christofolini, DM; Guedes, T; Santos, AA; Vieira-Neto, FH | 1 |
| Rousian, M; Rubini, E; Schoenmakers, S; Sinclair, KD; Snoek, KM; Steegers-Theunissen, RPM; Willemsen, SP | 1 |
| Jia, J; Liu, YH; Lu, GQ; Lu, LP; Shen, CY; Wu, H; Yi, MH | 1 |
| Chan, Y; Feng, N; Feng, Y; Li, Y; Su, L; Xu, Q; Yang, B; Zhu, B; Zhu, S; Zou, L | 1 |
| Bogatova, K; Enikeev, D; Gerasimova, E; Giniatullin, R; Hermann, A; Sitdikova, G; Yakovleva, O | 1 |
| Ballesteros, M; Cavallé-Busquets, P; Fernandez-Ballart, J; Grifoll, C; Masana, L; Murphy, MM; Ornosa-Martin, G; Ramos-Rodriguez, C; Rojas-Gómez, A; Solé-Navais, P; Ueland, PM | 1 |
| Du, Y; Qi, Q; Wang, L; Ye, F; Zhang, S; Zhou, J | 1 |
| Bala, R; Budhwar, S; Prakash, N; Sachan, S; Verma, R | 1 |
| Ara, R; Rahman, S; Sultana, MN | 1 |
| Abraham, VJ; Aronraj, J; Barney, AM; Cherian, AG; Christudass, CS; Danda, S; Jayaprakash, L; Marcus, TA | 1 |
| Bommarito, P; Clark, J; Fry, RC; Gamble, MV; García-Vargas, GG; Rubio-Andrade, M; Stýblo, M | 1 |
| Gu, H; Hu, J; Wang, X; Zhang, C | 1 |
| Cao, J; Wang, H | 1 |
| Burton, GJ; Capatina, N; Yung, HW | 1 |
| Feyh, P; Garbade, SF; Gramer, G; Hoffmann, GF; Kölker, S; Mütze, U; Reischl-Hajiabadi, AT; Weiss, KH | 1 |
| Arthurs, AL; Jankovic-Karasoulos, T; Roberts, CT; Smith, MD; Williamson, JM | 1 |
| Coutinho-Silva, R; Deon, M; Ferreira, FS; Júnior, OVR; Ribas, G; Rodrigues, FC; Savio, LEB; Schmitz, F; Silveira, JS; Vargas, CR; Wyse, ATS | 1 |
| Florindo, C; Gaspar, A; Janeiro, P; Lipari Pinto, P; Mexia, S; Rocha, H; Santos, RL; Tavares de Almeida, I; Vilarinho, L | 1 |
| Al-Jamea, LH; Al-Maqati, T; Al-Mulhim, A; Aldarmahi, A; Aldossary, MA; Alnaam, Y; Alzahrani, FM; Elnagi, E; Hassan, FM; Shaikh, SS | 1 |
| Kaur, J; Mahajan, A; Sapehia, D; Srinivasan, R | 1 |
| Bennett, D; Campbell, H; Duthie, S; Eguiagaray, IM; Li, X; Little, J; MacFarlane, AJ; McNulty, H; Momoli, F; Montazeri, A; Munger, R; Rubini, M; Senekal, M; Theodoratou, E; Wang, L | 1 |
| Cui, S; Li, S; Zhang, C; Zhu, X | 1 |
| Babu, GR; Deepa, R; Mandal, S; Van Schayck, OCP | 1 |
| Fukuoka, H; Horiguchi, S; Kagawa, Y; Kawabata, T; Kubo, Y; Nishikawa, M; Shoji, K; Tajima, A | 1 |
| Li, Q; Liu, H; Liu, T; Tang, Y; Yu, F | 1 |
| Cai, Y; Deng, Z; Hao, H; Li, S; Shi, C; Song, J; Yang, Q; Zhuang, G | 1 |
| Ogawa, S; Ota, K; Takahashi, T; Yoshida, H | 1 |
| Guo, J; Li, Y; Liu, S; Ren, H | 1 |
| Clément, A; Clément, P; Menezo, YJR; Viot, G | 1 |
| Djuric, DM; Gajić Bojić, M; Jovičić, S; Marinković, S; Škrbić, R; Stojiljković, MP; Đukanović, Đ | 1 |
| Du, YF; Gong, XL; Shi, HF; Wang, XL; Wei, Y; Wu, TC; Zhao, YY | 1 |
| Čerkez Habek, J; Gulin, D; Habek, D; Jerković Gulin, S; Vuković Bobić, M | 1 |
| Brazert, J; Pietryga, M; Radzicka, S; Zaborowski, MP; Ziolkowska, K | 1 |
| Bae, S; Caudill, MA; Jiang, X; King, JH; Klatt, KC; Kwan, STC; Malysheva, OV; Roberson, MS; Yan, J | 1 |
| Lamers, Y; Mujica-Coopman, MF; Schroder, TH; Sinclair, G; Tan, A; Vallance, HD | 1 |
| Ars, CL; Hofman, A; Jaddoe, VW; Marroun, HE; Muetzel, R; Nijs, IM; Schmidt, M; Steegers, EA; Steenweg-de Graaff, J; Tiemeier, H; van der Lugt, A; Verhulst, FC; White, T | 1 |
| Alim, A; Basit, A; Bhowmik, B; Hassan, Z; Hitman, GA; Hossain, IA; Hussain, A; Jahan, I; Khan, AKA; Majumder, A; Mdala, I; Moreira, NCDV; Siddique, T | 1 |
| Joshi, SR; Nandi, A; Randhir, K; Wadhwani, N; Wagh, G | 1 |
| Bagga, R; Kaur, J; Mahajan, A; Mohanraj, PS; Sapehia, D; Thakur, S | 1 |
| Li, H; Li, J; Li, S; Shao, S; Tian, Y; Wang, S; Yao, D; Zhang, H; Zhang, S; Zhu, Z | 1 |
| Hammouda, SAI; Mumena, WA | 1 |
| Jia, X; Jin, L; Ren, A; Wang, L; Wei, J; Wei, Y; Yin, S; Zhang, X | 1 |
| Jiang, Z; Lin, P; Lin, Z; Liu, L | 1 |
| Jain, A; Mishra, J; Puri, M; Saraswathy, KN; Tomar, A | 1 |
| Huang, J; Kong, H; Su, Y; Wang, F; Xin, H; Zheng, L | 1 |
| Azzini, E; Polito, A; Ruggeri, S | 1 |
| Alimohammadi, S; Ghiasvand, T; Khodadadi, I; Mazloomi, S; Shafiee, G | 1 |
| Liu, C; Luo, D; Ma, Y; Peng, D; Ping, L; Tang, J; Wang, Q; Wu, T | 1 |
| Chaudhry, SH; Gaudet, LM; MacFarlane, AJ; Rennicks White, R; Rodger, M; Smith, GN; Taljaard, M; Walker, MC; Wen, SW | 2 |
| Bhat, DS; Fall, CHD; Johnson, M; Jones, A; Krishnaveni, GV; Kumaran, K; Veena, SR; Yajnik, CS | 1 |
| Damvaeba, S; Han, A; Kwak-Kim, J; Mizunuma, H; Ota, K; Takahashi, T | 1 |
| Bross, P; Carlsen, J; Dipace, G; Gregersen, N; Mosegaard, S; Olsen, RKJ | 1 |
| Fukuoka, H; Kawabata, T; Kubo, Y; Mori, C; Nishikawa, M; Ohkubo, T; Oshida, K; Sakurai, K; Shoji, K; Yamashiro, Y; Yanagisawa, N | 1 |
| Dang, S; Kang, Y; Lei, F; Li, S; Liu, D; Liu, X; Mi, B; Pei, L; Qu, P; Shen, Y; Wang, D; Yan, H; Zeng, L; Zhu, Z | 1 |
| Bogatova, K; Gerasimova, E; Hermann, A; Mukhtarova, R; Shakhmatova, V; Sitdikova, G; Yakovlev, A; Yakovleva, O; Ziyatdinova, G | 1 |
| Andraweera, PH; Bianco-Miotto, T; Dekker, GA; Furness, DL; Grieger, JA; Grzeskowiak, LE; Jankovic-Karasoulos, T; Leemaqz, SY; McAninch, D; McCowan, LM; McCullough, D; Roberts, CT | 1 |
| Alharbi, MH; Hammouda, SA; Mumena, WA | 1 |
| Alinaghizadeh, M; Fatahi, S; Găman, MA; Kord Varkaneh, H; Mardali, F; Shidfar, F; Sohouli, MH | 1 |
| Deng, M; Di, L; Du, Y; Peng, Y; Tang, Z; Xiang, J; Yang, M; Yi, J; Zhai, X; Zhou, J | 1 |
| Chen, M; Huang, P; Jiang, Z; Lin, N; Shi, H; Sun, X; Wang, L; Yang, S; Yu, R | 1 |
| Bharadwaj, B; Dhiman, P; Pillai, RR; Premkumar, N; Rajendiran, S; Ranjan, VP; Wilson, AB | 1 |
| Lamers, Y; Mattman, A; Sinclair, G; Tan, A; Vallance, HD | 1 |
| Chen, DL; Hu, JR; Hu, L; Jia, JP; Jiang, XC; Liang, ZD | 1 |
| Chen, T; Gong, Z; Gu, X; Han, L; Liang, L; Qiu, W; Wang, L; Xiao, B; Xu, F; Ye, J; Zhang, H; Zhu, H | 1 |
| Felix, JF; Geurtsen, ML; Heil, SG; Jaddoe, VWV; Monasso, GS; Santos, S | 1 |
| Kaur, L; Mishra, J; Nava Saraswathy, K; Pal Sachdeva, M; Puri, M | 1 |
| Ellervik, C; Kjaergaard, AD; Kjaergaard, MN; Ming, WK; Wang, Z; Wu, Y | 1 |
| Balint, B; Blaise, S; Camadro, JM; Guéant, JL; Guéant-Rodriguez, RM; Hergalant, S; Lignières, L; Vanalderwiert, L | 1 |
| Bose, PD; Bose, S; Das, CR; Islam, M; Kashyap, N; Saikia, AK; Sultana, R; Tiwari, D | 1 |
| He, J; Huang, Z; Liu, W; Tang, S; Yu, Q; Zhang, Z | 1 |
| Felix, JF; Heil, SG; Jaddoe, VWV; Küpers, LK; Monasso, GS | 1 |
| Antoun, E; Dalrymple, KV; Flynn, AC; Godfrey, KM; Kitaba, NT; Lillycrop, KA; Painter, RC; Poston, L; Seed, PT; Sobczyńska-Malefora, A; van Weelden, W; White, SL | 1 |
| Bagga, R; Kaur, J; Mahajan, A; Sapehia, D | 1 |
| Chen, H; Chen, L; Chen, S; Huang, H; Jin, L; Wang, B; Wang, X; Wei, B; Wu, Z | 1 |
| Dai, C; Fei, Y; Li, J; Shi, Y; Yang, X | 1 |
| Mahmood, S; Nathenial, S; Younas, H; Younus, A | 1 |
| Agrawal, NR; Bala, R; Rajender, S; Singh, K; Singh, V; Verma, P; Verma, R; Yadav, N | 1 |
| Bao, Y; Gu, YH; Guo, J; Matsuura, M; Qiu, Z; Ushijima, M; Wang, F; Xie, X; Zhang, Q; Zhang, T; Zheng, P | 1 |
| Chen, D; Han, L; Liang, Z; Ma, Y | 1 |
| Feng, D; He, S; Li, J; Su, Z; Wu, Q; Ye, H | 1 |
| Deng, HY; Gong, FX; Qiao, ZY; Zheng, Y | 1 |
| Pieczyńska, J; Płaczkowska, S; Skórska, K; Sozański, R; Sołtysik, M | 1 |
| Chandyo, RK; Hysing, M; Kvestad, I; McCann, A; Ranjitkar, S; Schwinger, C; Sharma, S; Shrestha, LP; Shrestha, M; Strand, TA; Ueland, PM; Ulak, M | 1 |
| Chu, G; Lai, G; Liang, X; Wang, L; Zhao, Y | 1 |
| Jansson, T; Powell, TL; Rosario, FJ | 1 |
| Cai, S; Chan, JKY; Chong, MFF; Chong, YS; Godfrey, KM; Lai, JS; Lee, YS; Pang, WW; Shek, LPC; Tan, KH; van Dam, RM; Yap, FKP | 1 |
| Walker, SO; Wang, G; Wang, H; Xu, BP; Xu, RB | 1 |
| Dagnelie, PC; Jansen, EH; Moltó-Puigmartí, C; Simões-Wüst, AP; Thijs, C; van Dongen, MC | 1 |
| Abdelaziz, S; Deeb, WS; Katta, M; Maged, AM; Meshaal, H; Omran, E; Saad, H; Salah, E | 1 |
| Bandzeviciene, R; Bartkeviciene, D; Bartkeviciute, A; Boreikaite, E; Serapinas, D; Silkunas, M | 1 |
| Dai, XL; Jin, MH; Liu, GC; Mi, NN; Ren, XY; Wang, J; Wang, SQ; Zhang, J | 1 |
| Bao, J; Cai, M; Gao, F; Gu, X; Liu, F; Liu, H; Long, Y; Qiu, X; Qiu, Y | 1 |
| Barmaki, H; Faridvand, Y; Haiaty, S; Isazadeh, A; Kamrani, A; Maroufi, NF; Mokarizadeh, N; Mostafazadeh, M; Shiralizadeh, J | 1 |
| Barr, SI; Jung, B; Lamers, Y; Mattman, A; Schroder, TH; Sinclair, G; Vallance, HD | 1 |
| Han, A; Kwon, YH; Won, SB | 1 |
| Barjaktarovic, M; de Rijke, YB; Jaddoe, VWV; Korevaar, TIM; Peeters, RP; Steegers, EAP; Visser, TJ | 1 |
| Imai, K; Kajiyama, H; Kikkawa, F; Kotani, T; Maruta, E; Mitsui, T; Nakano, T; Nawa, A; Niwa, Y; Sumigama, S; Tamakoshi, K; Tsuda, H; Wang, J; Yamashita, M; Yoshida, S | 1 |
| Biasibetti-Brendler, H; Ferreira, F; Netto, CA; Pierozan, P; Schmitz, F; Wyse, ATS | 1 |
| Che, L; Chen, Y; Fang, Z; Feng, B; Li, J; Lin, Y; Liu, H; Mou, D; Wang, J; Xu, S | 1 |
| Fan, JX; Huang, HF; Qian, W; Sun, F; Zhang, C | 1 |
| Maged, AM | 1 |
| Beyazit, F; Pek, E | 1 |
| Bettinardi, N; Castiglioni, M; Ferrari, S; Ferraris Fusarini, C; La Vecchia, I; Noli, S; Paffoni, A; Parazzini, F; Somigliana, E | 1 |
| Chitra, T; Nandeesha, H; Papa, D; Sinha, P | 1 |
| Çoban, S; İğde, M; Yılmaz Keskin, E | 1 |
| Jiajin, L; Junxiao, C; Shuyan, C; Xiudi, W; Ying, W | 1 |
| Ballesteros, M; Cavallé-Busquets, P; Colomina, JM; Fernandez-Ballart, J; Inglès-Puig, M; Murphy, MM; Ornosa-Martín, G; Salat-Batlle, J; Solé-Navais, P; Ueland, PM | 1 |
| Gao, T; Gu, J; Guo, X; Li, D; Li, J; Li, K | 1 |
| Aniuliene, R; Bermagambetova, S; Gaiday, A; Tussupkaliyev, A | 1 |
| Akçay Yegin, G; Avşar, AF; Aydoğmuş, S; Ekiz, A; Kaya, B; Kaya, S; Keskin, HL | 1 |
| Chmurzynska, A; Malinowska, AM; Mlodzik, MA; Nowacka-Woszuk, J; Radziejewska, A; Szwengiel, A | 1 |
| Bermagambetova, SK; Daribay, ZZ; Dossimbetova, MB; Gaiday, AN; Sarsembayeva, LK; Tussupkaliyev, AB; Zhumagulova, SS | 1 |
| Fry, RC; Gamble, MV; Garcia-Vargas, G; Herring, AH; Ilievski, V; Laine, JE; Richardson, DB; Rubio-Andrade, M; Stýblo, M | 1 |
| Gu, X; Huang, Q; Liu, SY; Ni, ZM; Qin, LZ; Shen, W; Tian, P; Wang, Q; Ye, LX; Zeng, Y; Zhang, B | 1 |
| Bautista Nino, PK; Bramer, WM; Felix, JF; Franco, OH; Pantavos, A; Tuenter, A; Vitezova, A | 1 |
| Rizzo, A; Sciorsci, RL | 1 |
| Jiang, H; Tang, A; Xiang, Z; Yang, Y | 1 |
| De Vivo, I; Hogervorst, JGF; Janssen, BG; Madhloum, N; Nawrot, TS; Penders, J; Saenen, ND; Vanpoucke, C; Vrijens, K | 1 |
| Dolenc, MS; Geršak, K; Grželj, J; Mlinarič-Raščan, I; Vidmar, M | 1 |
| Becerra-Bayona, S; Beltran, M; Casas, JP; Diaz, LA; Dudbridge, F; Guio, E; Hingorani, AD; Mesa, CM; Miranda, J; Monsalve, G; Monterrosa, Á; Ortiz, R; Paez, MC; Quintero-Lesmes, DC; Saldarriaga, W; Sanin, JE; Serrano, NC | 1 |
| Arslanova, AN; Dmitrieva, SA; Giniatullin, RA; Khaertdinov, NN; Minibayeva, FV; Sitdikova, GF; Yakovlev, AV; Yakovleva, OV; Ziganshina, AR; Ziyatdinova, GK | 1 |
| Canals, J; Fernández-Ballart, J; Murphy, M; Roigé-Castellví, J | 1 |
| Dangat, K; Joshi, S; Khaire, A; Mehendale, S; Pisal, H; Randhir, K | 1 |
| Egert, S; González-Gross, M; Leschik-Bonnet, E; Neuhäuser-Berthold, M; Richter, M; Ströhle, A; Wagner, KH | 1 |
| Connell, MT; DeVilbiss, EA; Kim, K; Mills, JL; Mumford, SL; Schisterman, EF; Silver, RM; Sjaarda, LA | 1 |
| Bossenmeyer-Pourié, C; Daval, JL; Geoffroy, A; Guéant, JL; Helle, D; Pourié, G; Saber-Cherif, L; Umoret, R | 1 |
| Chen, X; Chen, Z; Cui, C; Huang, F; Jiang, X; Niu, J; Sun, J | 1 |
| Cheng, ZY; Du, YF; Shi, HF; Wang, XL; Wei, Y; Wu, TC; Yang, J; Zuo, XF | 1 |
| Joshi, SR; Nandi, AA; Wadhwani, NS | 1 |
| Barlik, M; Chmurzynska, A; Drews, K; KurzawiŃska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Wolski, H | 1 |
| Saravanan, P; Sukumar, N | 1 |
| Liu, B; Wu, F; Yang, H | 1 |
| Anani Sarab, G; Kooshkaki, O; Kordi Tammandani, D; Zarfeshan Fard, Y | 1 |
| Dymara-Konopka, W; Laskowska, M | 1 |
| Fu, J; Huang, J; Li, Q; Lin, Z; Sun, Y; Wang, W; Xu, J; Zeng, D | 1 |
| Aloui, M; Baara, A; Ben Fradj, MK; Ben Halima, M; Ben Jemaa, N; Ben Wafi, S; Boulares, M; Feki, M; Gaigi, SS; Jemaa, R; Kallel, A; Lassoued, M; Mahjoubi, I; Marrakchi, R; Midani, F; Nasri, K; Omar, S; Soussi, M | 1 |
| Bayraktar, N; Gulumser, C; Kocaman, E; Sahin-Uysal, N; Varan, B; Yanık, F | 1 |
| Diwaker, A; Kishore, D | 1 |
| Andguladze, S; Asanidze, E; Kristesashvili, J | 1 |
| Baghurst, PA; Coat, S; Gatford, KL; Hague, WM; Houda, CM; Lu, ZX; Owens, JA; Rowan, JA; Sikaris, K | 1 |
| Böttiger, AK; Farkas, SA; Finnell, RH; Isaksson, HS; Nilsson, TK; Ren, A | 1 |
| Croxford, R; Kim, YI; Li, J; Ly, A; Sie, KK; Sohn, KJ | 1 |
| Bodnar, LM; Chang, CC; Evans, RW; Luther, JF; Newby, PK; Tomedi, LE; Wisner, KL | 1 |
| de Jonge, LL; Heppe, DH; Hofman, A; Jaddoe, VW; Rob Taal, H; Steegers, EA; van den Hil, LC; van der Heijden, AJ | 1 |
| Barman, SA; Bhalla, VK; Ganapathy, V; Newman, TM; Offermanns, S; Prasad, PD; Smith, SB; Sonne, SR; White, RE; Zhu, S | 1 |
| Ballesteros, M; Berrocal-Zaragoza, MI; Cavallé-Busquets, P; Fernandez-Ballart, JD; Fernàndez-Roig, S; Murphy, MM; Salat-Batlle, J; Ueland, PM | 1 |
| Chedraui, P; Durán, A; Liem, KH; Pérez-López, FR; Rodas, L; Teran, E; Vásquez, CJ; Yanez, P | 1 |
| Cicek, E; Colak, A; Cosar, H; Erdemir, A; Kahramaner, Z; Ozer, EA; Sutcuoglu, S; Turkoglu, E | 1 |
| Ghosh, PK; Kaur, L; Mukhopadhhyay, R; Puri, M; Sachdeva, MP; Saraswathy, KN; Trivedi, SS; Walia, GK | 1 |
| Linask, KK | 1 |
| Franco, OH; Heppe, DH; Hofman, A; Jaddoe, VW; Medina-Gomez, C; Rivadeneira, F | 1 |
| Dornan, J; Marshall, B; McNulty, B; McNulty, H; Molloy, AM; Pentieva, K; Scott, JM; Ward, M | 1 |
| Laskowska, K; Laskowska, M; Oleszczuk, J; Terbosh, M | 1 |
| Humphries, D; Rechenberg, K | 1 |
| Cosar, A; Ozcan, O | 1 |
| Bailey, KR; Garovic, VD; Kardia, SL; Kullo, IJ; Mosley, TH; Turner, ST; White, WM; Wiste, HJ | 1 |
| Joshi, SR; Mehendale, SS; Pisal, HR; Wadhwani, NS | 1 |
| Hoey, L; McNulty, H; Pentieva, K; Strain, J; Ward, M | 1 |
| Joshi, SR; Kale, AA; Sable, PS | 1 |
| Haruna, M; Matsuzaki, M; Murashima, S; Murayama, R; Ota, E; Sasaki, S; Shiraishi, M; Yeo, S | 1 |
| Chang, N; Cho, SJ; Gwak, HS; Ha, EH; Kim, HS; Kim, KN; Kim, YJ; Lee, H; Lee, HA; Park, EA; Park, H | 1 |
| Deshmukh, U; Katre, P; Yajnik, CS | 1 |
| Cha, SH; Choi, YS; Jeon, YJ; Kim, JH; Kim, NK; Kim, YR; Lee, BE; Lee, WS; Rah, H; Shin, JE | 1 |
| Brunton, PJ; Fleetwood-Walker, S; Gooding, HL; Mitchell, R; Russell, JA; Sun, L | 1 |
| Kumar, A; Raman, R; Sukla, KK; Tiwari, PK | 1 |
| Ali, NS; Michels, KB; Osterhues, A | 1 |
| Ahumada, V; Arraztoa, JA; Bustos, V; Dobierzewska, A; España-Perrot, PP; Fernández, XB; Figueroa-Diesel, H; Illanes, SE; Pérez-Sepúlveda, A; Rice, GE | 1 |
| Jerome-Majewska, LA; Moreno-Garcia, MA; Rosenblatt, DS | 1 |
| Gray, C; Li, M; Reynolds, CM; Sloboda, DM; Vickers, MH | 1 |
| Fall, CH; Karat, SC; Krishnaveni, GV; Veena, SR; Yajnik, CS | 1 |
| Alberto, JM; Daval, JL; El Hajj Chehadeh, S; Guéant, JL; Leininger-Muller, B; Martin, N; Pourié, G | 1 |
| Chen, JC; Chuang, CH; Hsiao, CT; Lee, YY; Li, WC; Loke, SS; Sheu, BF | 1 |
| Scherer, E; Schweinberger, BM; Schwieder, L; Sitta, A; Vargas, CR; Wyse, AT | 1 |
| Finer, S; Hitman, G; Saravanan, P; Yajnik, C | 1 |
| Campion, J; Cordero, P; Martinez, JA; Milagro, FI | 1 |
| Gadgil, MS; Joshi, KS; Naik, SS; Otiv, SR; Pandit, AN; Patwardhan, BK | 1 |
| Rogers, E; Shea, TB | 1 |
| Brenna, JT; Gadgil, M; Joshi, K; Joshi, R; Otiv, S; Pandit, A; Patwardhan, B | 1 |
| Koletzko, B; Obeid, R; Pietrzik, K | 1 |
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| Bhat, DS; Coyaji, KJ; Deshpande, SS; Deshpande, VU; Fall, CH; Fisher, DJ; Jackson, AA; Joglekar, CV; Joshi, N; Lubree, HG; Naik, SS; Rao, S; Refsum, H; Rege, SS; Yajnik, CS | 1 |
| Ananth, CV; De Marco, C; Elsasser, DA; Getahun, D; Peltier, MR; Rozen, R; Smulian, JC | 1 |
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| Blom, HJ; Boers, GH; Eskes, TK; Goddijn-Wessel, TA; Spuijbroek, MD; Steegers-Theunissen, RP; van de Molen, EF; Wouters, MG | 1 |
| Dekker, GA; van Geijn, HP | 1 |
| Conley, MR; Mills, JL | 1 |
| Chard, T; Eskes, TK; Steegers-Theunissen, RP; van Raaij-Selten, B; Wathen, NC | 1 |
| Kvåle, G; Nordrehaug, JE; Nygård, O; Refsum, H; Stensvold, I; Ueland, PM; Vollset, SE | 1 |
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| Brouwer, IA; de Bree, A; Steegers-Theunissen, RP; van Dusseldorp, M; van het Hof, KH | 1 |
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| Blom, HJ; Boers, GH; Eskes, TK; Nelen, WL; Steegers, EA; Thomas, CM | 1 |
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| Crombleholme, WR; Evans, RW; Majors, AK; Ness, RB; Ojimba, JI; Powers, RW; Roberts, JM | 1 |
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| Bester, MJ; Blom, HJ; Christianson, A; Delport, R; Potgieter, H; Ubbink, JB; Van Allen, MI; van der Merwe, A; Venter, PA; Vermaak, WJ | 1 |
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| Acton, S; Cliver, S; Johanning, GL; Johnston, KE; Owen, J; Tamura, T; Wenstrom, KD | 1 |
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| King, IB; Mahomed, K; Malinow, MR; Rajkovic, A; Rozen, R; Williams, MA | 1 |
| Demacker, PN; Hectors, MP; Peters, WH; Raijmakers, MT; Steegers, EA; Zusterzeel, PL | 1 |
| Blom, HJ; den Heijer, M; Eskes, TK; Nelen, WL; Steegers, EA; Thomas, CM | 1 |
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| Emblem, BM; Gjessing, HK; Irgens, LM; Monsen, AL; Refsum, H; Tverdal, A; Ueland, PM; Vollset, SE | 1 |
| Blom, HJ; Bulten, J; Eskes, TK; Hanselaar, AG; Nelen, WL; Steegers, EA | 1 |
| Johnson, WG; Scholl, TO | 1 |
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| Arends, GE; Blom, HJ; Eskes, TK; Heil, SG; Nelen, WL; van der Molen, EF; van der Put, NJ | 1 |
| Blom, HJ; Eskes, TK; Monnens, LA; Nováková, I; van der Molen, EF; Verbruggen, B | 1 |
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| Duarte, N; Trudinger, BJ; Wang, J; Wang, XL; Wilcken, DE | 1 |
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| Cameron, D; Fontaine, RN; Glueck, CJ; Moore, SK; Phillips, H; Sieve-Smith, L; Tracy, T; Wang, P | 1 |
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| Donnelly, JG; Isotalo, PA; Wells, GA | 1 |
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| Refsum, H; Schneede, J; Ueland, PM | 1 |
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| González, S; López-Quesada, EL; Vilaseca, MA | 1 |
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| Ferguson, SE; Smith, GN; Walker, MC | 1 |
| Baker, PJ; Banerjee, R; Brody, LC; Garrett, L; Harris, M; Liu, ML; Shane, B; Stitzel, M; Swanson, DA; Wu, J | 1 |
| Okatani, Y; Reiter, RJ; Wakatsuki, A | 2 |
| Mulder, TP; Peters, WH; Raijmakers, MT; Roes, EM; Steegers, EA; Zusterzeel, PL | 1 |
| De Falco, M; Lieto, AD; Pollio, F; Pontillo, M; Scaramellino, M | 1 |
| Friedler, S; Kornberg, Y; Raziel, A; Ron-El, R; Schachter, M; Sela, BA | 1 |
| Larrabure, G; Rene Malinow, M; Sanchez, SE; Ware-Jauregui, S; Williams, MA; Zhang, C | 1 |
| Cikot, RJ; de Boo, TM; Merkus, HM; Steegers, EA; Steegers-Theunissen, RP; Thomas, CM | 1 |
| Aarnoudse, JG; Arngrímsson, R; Bastiaans, EJ; de Vries, JI; Dekker, GA; Kostense, PJ; Lachmeijer, AM; Pals, G; ten Kate, LP | 1 |
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| Barrera Saldaña, H; García Cavazos, R; Garza Elizondo, M; López Valdez, R; Martínez de Villarreal, LE; Perales Dávila, J; Rojas Martínez, A; Saldívar Rodríguez, D; Triana Saldaña, H; Valdez Leal, R; Zacarías Villarreal Pérez, J | 1 |
| Bocanová, E; Cabrnochová, I; Calda, P; Dolezal, A; Dubská, L; Dudková, V; Dvoráková, J; Hyánek, J; Jenícek, J; Krofta, L; Loucka, M; Machácková, L; Martiníková, V; Pejznochová, H; Vinglerová, H; Zivný, J | 1 |
| Peters, WH; Raijmakers, MT; Roes, EM; Steegers, EA; van Der Wildt, B | 1 |
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| Bjørke Monsen, AL; Guttormsen, AB; Markestad, T; Refsum, H; Solheim, E; Ueland, PM; Vollset, SE | 1 |
| Bailie, KE; Lappin, TR; McMullin, MF; Savage, GA; White, R; Young, PB | 1 |
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| Bondevik, GT; Kvåle, G; Lie, RT; Refsum, H; Schneede, J; Ulstein, M | 1 |
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| Chen, L; Li, K; Sun, Y | 1 |
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| Andreussi, L; Arata, L; Calevo, MG; Cama, A; Capra, V; De Marco, P; Finnell, RH; Merello, E; Moroni, A | 1 |
| Nygård, O; Refsum, H; Ueland, PM; Vollset, SE | 1 |
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129 review(s) available for homocysteine and Pregnancy
| Article | Year |
|---|---|
High level of homocysteine is associated with pre-eclampsia risk in pregnant woman: a meta-analysis.
Topics: Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Pregnant Women | 2022 |
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neural Tube Defects; Pregnancy; Thymidylate Synthase; Vitamin B 12 | 2022 |
The association of thrombophilia in women with severe obstetric complications.
Topics: Female; Homocysteine; Humans; Mass Screening; Pregnancy; Pregnancy Complications; Risk Factors; Thrombophilia | 2022 |
Homocysteine: Its Possible Emerging Role in At-Risk Population Groups.
Topics: Aging; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Cardiovascular Diseases; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Neurodegenerative Diseases; Osteoporosis; Pre-Eclampsia; Pregnancy; Risk Factors | 2020 |
Riboflavin Deficiency-Implications for General Human Health and Inborn Errors of Metabolism.
Topics: Acyl-CoA Dehydrogenases; Aging; Animals; Diet; Electron Transport; Energy Metabolism; Fatty Acids; Female; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Genetic Variation; Homocysteine; Humans; Immune System; Metabolism, Inborn Errors; Mitochondria; Mutation; Phenotype; Pregnancy; Protein Folding; Riboflavin; Riboflavin Deficiency | 2020 |
Association between abnormal maternal serum levels of vitamin B12 and preeclampsia: a systematic review and meta-analysis.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Observational Studies as Topic; Pre-Eclampsia; Pregnancy; Vitamin B 12; Young Adult | 2021 |
Homocysteine and female fertility, pregnancy loss and offspring birthweight: a two-sample Mendelian randomization study.
Topics: Abortion, Spontaneous; Birth Weight; Female; Fertility; Folic Acid; Genome-Wide Association Study; Homocysteine; Humans; Male; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy | 2022 |
A Novel Review of Homocysteine and Pregnancy Complications.
Topics: Abortion, Habitual; Aging; Birth Weight; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2021 |
A narrative review on the role of folate-mediated one-carbon metabolism and its associated gene polymorphisms in posing risk to preeclampsia.
Topics: Carbon; Female; Folic Acid; Homocysteine; Humans; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy | 2021 |
Hyperhomocysteinemia and low vitamin B12 are associated with the risk of early pregnancy loss: A clinical study and meta-analyses.
Topics: Abortion, Spontaneous; Adult; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Nutritional Physiological Phenomena; Meta-Analysis as Topic; Nutritional Status; Odds Ratio; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
Meta-analysis: association of homocysteine with recurrent spontaneous abortion.
Topics: Abortion, Habitual; Abortion, Spontaneous; China; Female; Homocysteine; Humans; Pregnancy; Risk Factors | 2021 |
Homocysteine level and gestational diabetes mellitus: a systematic review and meta-analysis.
Topics: Diabetes, Gestational; Female; Homocysteine; Humans; Pregnancy | 2021 |
Effect of homocysteine on pregnancy: A systematic review.
Topics: Abortion, Spontaneous; Abruptio Placentae; Female; Fetal Growth Retardation; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy | 2018 |
Folate, vitamin B12, and homocysteine in smoking-exposed pregnant women: A systematic review.
Topics: Female; Folic Acid; Homocysteine; Humans; Maternal Exposure; Mothers; Pregnancy; Pregnancy Complications; Smoking; Smoking Cessation; Vitamin B 12 | 2019 |
Role of homocysteine metabolism in animal reproduction: A review.
Topics: Animals; Female; Homocysteine; Oxidative Stress; Pregnancy; Pregnancy, Animal | 2019 |
Medicines associated with folate-homocysteine-methionine pathway disruption.
Topics: Enzyme Inhibitors; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Pregnancy; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Vitamin B 12 Deficiency | 2019 |
The Role of Nitric Oxide, ADMA, and Homocysteine in The Etiopathogenesis of Preeclampsia-Review.
Topics: Arginine; Female; Homocysteine; Humans; Nitric Oxide; Pre-Eclampsia; Pregnancy; Signal Transduction | 2019 |
Nutritional interventions in depression and perinatal depression.
Topics: Brain; Depression; Depression, Postpartum; Fatty Acids, Unsaturated; Female; Homocysteine; Humans; Nutritional Physiological Phenomena; Pregnancy | 2013 |
The role of folic acid fortification in neural tube defects: a review.
Topics: Biological Availability; Choline; Edible Grain; Female; Folic Acid; Folic Acid Antagonists; Food, Fortified; Homocysteine; Humans; Neural Tube Defects; Nutritional Requirements; Pregnancy; Recommended Dietary Allowances; United States; Vitamin B 12 | 2013 |
Vitamin B(12) metabolism during pregnancy and in embryonic mouse models.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acyl Coenzyme A; Animals; Disease Models, Animal; Embryonic Development; Female; Homocysteine; Humans; Methionine; Methylmalonyl-CoA Mutase; Mice; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
The role of the one-carbon cycle in the developmental origins of Type 2 diabetes and obesity.
Topics: Adiposity; Carbon Cycle; Diabetes Mellitus, Type 2; Environmental Exposure; Female; Fetal Development; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant, Newborn; Insulin Resistance; Male; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Obesity; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Lifetime requirement of the methionine cycle for neuronal development and maintenance.
Topics: Developmental Disabilities; Female; Folic Acid; Homocysteine; Humans; Methionine; Pregnancy; Prenatal Care; S-Adenosylmethionine; Vitamin B 12; Vitamin B Complex | 2014 |
Critical evaluation of lowering the recommended dietary intake of folate.
Topics: Anemia; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Genetic Markers; Homocysteine; Humans; Life Style; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Recommended Dietary Allowances; Treatment Outcome | 2014 |
Systematic review and metaanalysis on nonclassic cardiovascular biomarkers after hypertensive pregnancy disorders.
Topics: Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hypertension; Hypertension, Pregnancy-Induced; Models, Statistical; Pregnancy | 2014 |
"Polymorphisms in folate metabolism genes as maternal risk factor for neural tube defects: an updated meta-analysis".
Topics: Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Odds Ratio; Polymorphism, Single Nucleotide; Pregnancy; Publication Bias; Risk Factors | 2015 |
Folic acid and autism: What do we know?
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Autism Spectrum Disorder; Child; Child Nutritional Physiological Phenomena; Diet; Dietary Supplements; Evidence-Based Medicine; Female; Fetal Development; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Reproducibility of Results; Risk Factors | 2016 |
Male factors in ART outcome prediction.
Topics: Anti-Mullerian Hormone; Biomarkers; DNA Fragmentation; Female; Folic Acid; Homocysteine; Humans; Infertility, Male; Male; Pregnancy; Pregnancy Rate; Prognosis; Reactive Oxygen Species; Reproductive Techniques, Assisted; Spermatozoa; Treatment Outcome | 2015 |
Early pregnancy B vitamin status, one carbon metabolism, pregnancy outcome and child development.
Topics: Betaine; Carbon; Child; Child Development; Child, Preschool; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Sarcosine; Vitamin B 12 | 2016 |
Serum homocysteine level and gestational diabetes mellitus: A meta-analysis.
Topics: Adult; Diabetes, Gestational; Female; Homocysteine; Humans; Pregnancy | 2016 |
Maternal biomarkers of methylation status and non-syndromic orofacial cleft risk: a meta-analysis.
Topics: Biomarkers; Cleft Lip; Cleft Palate; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Vitamin B 12 | 2016 |
Elevated homocysteine levels in mothers with neural tube defects: a systematic review and meta-analysis.
Topics: Case-Control Studies; Female; Folic Acid; Hematinics; Homocysteine; Humans; Neural Tube Defects; Pregnancy | 2017 |
[Do folates have an impact on fertility?].
Topics: DNA Methylation; Female; Fertility; Folic Acid; Homocysteine; Humans; Infertility; Male; Pregnancy; Pregnancy Complications; Reproduction; Vitamin B Complex | 2008 |
Public health significance of elevated homocysteine.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neural Tube Defects; Pregnancy; Public Health; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
[Homocysteine metabolism disorders as a potential predictor of preeclamsia].
Topics: Biomarkers; Female; Health Knowledge, Attitudes, Practice; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Welfare; Pre-Eclampsia; Pregnancy; Prenatal Care; Primary Prevention; Risk Assessment; Risk Factors | 2008 |
The search for genetic polymorphisms in the homocysteine/folate pathway that contribute to the etiology of human neural tube defects.
Topics: Clinical Trials as Topic; DNA Mutational Analysis; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Metabolic Networks and Pathways; Models, Biological; Neural Tube Defects; Polymorphism, Genetic; Pregnancy; Research | 2009 |
Folic acid, methylation and neural tube closure in humans.
Topics: Female; Folic Acid; Genetic Variation; Homocysteine; Humans; Metabolic Networks and Pathways; Methylation; Methyltransferases; Models, Biological; Neural Tube; Neural Tube Defects; Pregnancy | 2009 |
[Present role of homocysteine in clinical medicine].
Topics: Adolescent; Adult; Cardiovascular Diseases; Child; Child, Preschool; Ectopia Lentis; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Life Style; Male; Middle Aged; Myopia; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Cobalamin, folic acid, and homocysteine.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2009 |
Molecular mechanisms of homocysteine toxicity.
Topics: Animals; Apoptosis; Blood Cells; Cardiovascular Diseases; Carnosine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neurodegenerative Diseases; Neurons; Pregnancy; Receptors, N-Methyl-D-Aspartate; Risk Factors | 2009 |
Folate-mediated one-carbon metabolism and its effect on female fertility and pregnancy viability.
Topics: DNA Methylation; Female; Fertility; Fetal Development; Folic Acid; Folic Acid Deficiency; Genetic Variation; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Pregnancy Maintenance; Pregnancy Outcome | 2010 |
Clinical diagnostics for homocysteine: a rogue amino acid?
Topics: Animals; Avitaminosis; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Mental Disorders; Molecular Structure; Neurodegenerative Diseases; Oxidation-Reduction; Pathology, Molecular; Pregnancy; Pregnancy Complications | 2010 |
Homocysteine is transported by the microvillous plasma membrane of human placenta.
Topics: Amino Acid Transport System A; Amino Acid Transport System L; Amino Acid Transport System y+L; Biological Transport; Cell Membrane; Female; Homocysteine; Humans; Microvilli; Models, Biological; Placenta; Pregnancy; Sulfur Radioisotopes | 2011 |
Teratogenicity and underlying mechanisms of homocysteine in animal models: a review.
Topics: Abnormalities, Drug-Induced; Animals; Chickens; Congenital Abnormalities; Embryonic Development; Female; Fetal Development; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Neural Crest; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Rats; Teratogens | 2010 |
Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects.
Topics: Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Models, Biological; Neural Tube Defects; Pregnancy; Risk Factors | 2011 |
Homocysteine in pregnancy.
Topics: Animals; Biomarkers; Female; Fetal Development; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Reproduction | 2011 |
[Genes involved in folate metabolim and neural tube defects].
Topics: Female; Folic Acid; Folic Acid Transporters; Genetic Predisposition to Disease; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Single Nucleotide; Pregnancy; Reduced Folate Carrier Protein; Risk Factors | 2011 |
Combined methylmalonic acidemia and homocystinuria, cblC type. II. Complications, pathophysiology, and outcomes.
Topics: Adolescent; Adult; Aged; Amino Acid Metabolism, Inborn Errors; Carrier Proteins; Central Nervous System; Child; Child, Preschool; Eye Diseases; Female; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Middle Aged; Oxidoreductases; Pregnancy; Vitamin B 12 Deficiency | 2012 |
Maternal homocysteine and small-for-gestational-age offspring: systematic review and meta-analysis.
Topics: Birth Weight; Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Infant, Small for Gestational Age; Odds Ratio; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 2012 |
Methionine, homocysteine, one carbon metabolism and fetal growth.
Topics: Adult; Animals; Carbon; Dietary Proteins; Energy Intake; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Methionine; Pregnancy; Rats; Vitamin B 12; Vitamins | 2012 |
Biomarkers in pre-eclampsia: a novel approach to early detection of the disease.
Topics: Antigens, CD; Arginine; Biomarkers; Endoglin; Female; Galectins; Homocysteine; Humans; Leptin; Pre-Eclampsia; Pregnancy; Pregnancy Proteins; Pregnancy Trimester, First; Pregnancy-Associated Plasma Protein-A; Receptors, Cell Surface; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2012 |
Is there a relationship between risk factors for oral clefts?
Topics: Birth Order; Cleft Lip; Cleft Palate; Confounding Factors, Epidemiologic; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Maternal-Fetal Exchange; Odds Ratio; Pregnancy; Risk Factors; Smoking; Socioeconomic Factors | 2002 |
Homocysteine in the context of cobalamin metabolism and deficiency states.
Topics: Female; Homocysteine; Humans; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Homocysteine, folic acid and B-group vitamins in obstetrics and gynaecology.
Topics: Abortion, Spontaneous; Congenital Abnormalities; Contraceptives, Oral, Hormonal; Female; Fetal Death; Fetal Growth Retardation; Folic Acid; Gynecology; Homocysteine; Humans; Menopause; Neural Tube Defects; Obstetrics; Pre-Eclampsia; Pregnancy; Uterine Cervical Dysplasia; Vitamin B Complex | 2003 |
Homocysteine and pregnancy.
Topics: Female; Homocysteine; Humans; Hyperhomocysteinemia; Neural Tube Defects; Placenta Diseases; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic | 2003 |
[Hyperhomocysteinemia during pregnancy as a risk factor of preeclampsia].
Topics: Carbohydrate Metabolism; Female; Homocysteine; Humans; Hyperhomocysteinemia; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors; Ultrasonography, Doppler; Uterus | 2003 |
Changes in haemostasis during normal pregnancy: does homocysteine play a role in maintaining homeostasis?
Topics: Female; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Neural Tube Defects; Placenta Diseases; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Thromboembolism | 2003 |
[Hyperhomocysteinemia and pregnancy complications].
Topics: Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Patient Education as Topic; Pregnancy; Pregnancy Complications; Pregnancy, High-Risk; Risk Factors | 2004 |
[Homocysteine and pregnancy].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Female; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Pre-Eclampsia; Pregnancy | 2004 |
Nutritional importance of choline for brain development.
Topics: Animals; Apoptosis; Brain; Cell Division; Cell Movement; Cell Proliferation; Choline; Female; Folic Acid; Gene Expression Regulation, Developmental; Homocysteine; Humans; Male; Memory; Neurons; Pregnancy | 2004 |
Thrombophilias and recurrent pregnancy loss: a critical appraisal of the literature.
Topics: Abortion, Habitual; Antibodies, Antiphospholipid; Factor V; Female; Gestational Age; Homocysteine; Humans; Mutation; Odds Ratio; Pregnancy; Protein C; Prothrombin; Thrombophilia | 2005 |
Mapping the theories of preeclampsia: the role of homocysteine.
Topics: Adult; Age Factors; Biomarkers; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Maternal Age; Parity; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Primary Prevention; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Survival Rate; Vitamin B 12 | 2005 |
[Thrombophilias and vascular placental pathology. A survey of the literature].
Topics: Activated Protein C Resistance; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Cohort Studies; Confidence Intervals; Drug Therapy, Combination; Female; Fetal Death; Fetal Growth Retardation; Forecasting; Homocysteine; Humans; Infant, Newborn; Meta-Analysis as Topic; Multivariate Analysis; Odds Ratio; Placenta; Placenta Diseases; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Prospective Studies; Retrospective Studies; Risk Factors; Thrombophilia; Thrombosis | 2005 |
Multiple micronutrients in pregnancy and lactation: an overview.
Topics: Anemia, Iron-Deficiency; Female; Homocysteine; Humans; Infant; Infant, Newborn; Lactation; Micronutrients; Milk, Human; Pregnancy | 2005 |
Water-soluble vitamins: research update.
Topics: Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Neural Tube Defects; Niacinamide; Nutritional Requirements; Pregnancy; Riboflavin; Riboflavin Deficiency; Solubility; Thiamine; Thiamine Deficiency; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 2005 |
Homocysteine and folic acid: implications for pregnancy.
Topics: Canada; Female; Folic Acid; Food, Fortified; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; International Cooperation; National Health Programs; Neural Tube Defects; Pre-Eclampsia; Pregnancy; United States | 2005 |
The significance of folic acid for epilepsy patients.
Topics: Anticonvulsants; Epilepsy; Female; Folic Acid; History, 20th Century; Homocysteine; Humans; Male; Methionine; Models, Biological; Neural Tube Defects; Pregnancy; Vascular Diseases | 2005 |
Homocysteine, folic acid and vitamin B12 in relation to pre- and postnatal health aspects.
Topics: Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Pregnancy; Pregnancy Outcome; Vitamin B 12 | 2005 |
[Homocysteine--risk factor or risk indicator?].
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Child; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex | 2005 |
Genetic variation in genes of folate metabolism and neural-tube defect risk.
Topics: Adult; Female; Folic Acid; Genetic Variation; Homocysteine; Humans; Neural Tube Defects; Polymorphism, Genetic; Pregnancy; Risk Factors | 2006 |
Folate and human reproduction.
Topics: Diet; Dietary Supplements; Female; Fetal Development; Fetus; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Lactation; Male; Neural Tube Defects; Nutritional Requirements; Placenta; Pregnancy; Pregnancy Complications; Reproduction | 2006 |
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine | 2006 |
The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease.
Topics: Adult; Aged; Aging; Bone Density; Cardiovascular Diseases; Cognition Disorders; Depression; Disease; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mortality; Norway; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors | 2006 |
Hypertension as a low-grade systemic inflammatory condition that has its origins in the perinatal period.
Topics: Female; Homocysteine; Humans; Hypertension; Inflammation; Oxidative Stress; Postpartum Period; Pregnancy; Superoxides | 2006 |
Homocysteine: a role in fetal programming?
Topics: Diet, Protein-Restricted; Disease Susceptibility; DNA Methylation; Female; Fetal Development; Gene Expression Regulation; Homocysteine; Humans; Maternal-Fetal Exchange; Phenotype; Pregnancy | 2006 |
Schizophrenia and neural tube defects: comparisons from an epidemiological perspective.
Topics: Birth Intervals; Female; Fetal Development; Folic Acid Deficiency; Geography; Homocysteine; Humans; Incidence; Methylenetetrahydrofolate Dehydrogenase (NAD+); Neural Tube Defects; Nutrition Disorders; Phenotype; Pregnancy; Risk Factors; Schizophrenia; Seasons; Starvation | 2007 |
Hyperhomocysteinaemia: a critical review of old and new aspects.
Topics: Age Factors; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors; Sex Factors | 2007 |
Hyperhomocysteinemia and venous thrombosis.
Topics: Female; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Pregnancy Complications, Hematologic; Prospective Studies; Retrospective Studies; Venous Thrombosis | 2007 |
Inherited thrombophilia: key points for genetic counseling.
Topics: Abortion, Habitual; Antithrombin III Deficiency; Factor V; Female; Genetic Counseling; Genetic Predisposition to Disease; Genetic Testing; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Prothrombin; Referral and Consultation; Risk Assessment; Thromboembolism; Thrombophilia | 2007 |
The deoxyuridine suppression test: a review of its clinical and research applications.
Topics: Alcoholism; Anemia, Hemolytic; Anticonvulsants; Bone Marrow Cells; Bone Marrow Diseases; Cells; Deoxyuridine; Erythrocytes, Abnormal; Female; Fluorouracil; Folic Acid; Folic Acid Deficiency; Formyltetrahydrofolates; Homocysteine; Humans; Hypothyroidism; Lymphocyte Activation; Methionine; Pregnancy; Pregnancy Complications; Statistics as Topic; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1981 |
Is an elevated circulating maternal homocysteine concentration a risk factor for neural tube defects?
Topics: Biomarkers; Female; Homocysteine; Humans; Methionine; Methylation; Neural Tube Defects; Pregnancy; Risk Factors | 1995 |
Folate status, women's health, pregnancy outcome, and cancer.
Topics: Adolescent; Adult; Animals; Arteriosclerosis; Female; Folic Acid Deficiency; Homocysteine; Humans; Infant; Maternal-Fetal Exchange; Methionine; Middle Aged; Neural Tube Defects; Papillomaviridae; Pregnancy; Rats; Tumor Virus Infections; Uterine Cervical Neoplasms; Women's Health | 1993 |
Myeloproliferative and metabolic causes.
Topics: Amino Acid Metabolism, Inborn Errors; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Female; Hemoglobinopathies; Hemoglobinuria, Paroxysmal; Homocysteine; Humans; Inflammation; Male; Metabolic Diseases; Myeloproliferative Disorders; Neoplasms; Nephrotic Syndrome; Postpartum Period; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Complications, Hematologic; Purpura, Thrombotic Thrombocytopenic; Thrombosis | 1994 |
Critical points for determining moderate hyperhomocyst(e)inaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Female; Homocysteine; Humans; Male; Postmenopause; Pregnancy; Pregnancy Complications; Premenopause | 1995 |
More folic acid for everyone, now.
Topics: Adult; Aged; Anencephaly; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Infant, Newborn; Male; Pregnancy; Risk Factors; Spinal Dysraphism; United States; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Homocysteine and neural tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Infant, Newborn; Mice; Neural Tube Defects; Pregnancy; Randomized Controlled Trials as Topic; Rats; Vitamin B 12 | 1996 |
Endothelial dysfunction in preeclampsia. Part II: Reducing the adverse consequences of endothelial cell dysfunction in preeclampsia; therapeutic perspectives.
Topics: Antibodies, Anticardiolipin; Aspirin; Endothelium, Vascular; Female; Fibrinolytic Agents; Homocysteine; Humans; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Protein S Deficiency | 1996 |
Folic acid to prevent neural tube defects: scientific advances and public health issues.
Topics: Diet; Female; Folic Acid; Genetic Testing; Hematinics; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Prenatal Care; Risk Factors | 1996 |
Folic acid in the prevention of birth defects.
Topics: Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Methionine; Neural Tube Defects; Preconception Care; Pregnancy; Prenatal Care | 1996 |
The role of folic acid in deficiency states and prevention of disease.
Topics: Anemia, Macrocytic; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Nutritional Physiological Phenomena; Pregnancy | 1997 |
Hyperhomocysteinaemia and associated disease.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Arteriosclerosis; Female; Homocysteine; Homocystinuria; Homozygote; Humans; Lyases; Metabolism, Inborn Errors; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Oxidoreductases; Pregnancy; Pregnancy Complications; Thrombophlebitis | 1997 |
Folate intake in Europe: recommended, actual and desired intake.
Topics: Adult; Europe; Female; Folic Acid; Food; Homocysteine; Humans; Male; Neural Tube Defects; Nutrition Policy; Pregnancy; Risk Factors | 1997 |
[Folates and the neural tube. Review of the literature].
Topics: Animals; Europe; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Methionine; Methylation; Neural Crest; Neural Tube Defects; Preconception Care; Pregnancy; Prenatal Care; Prevalence; Risk Factors | 1997 |
[Hyperhomocysteinemia: a new marker of vascular risk: affected vascular areas, its role in the pathogenesis of arteriosclerosis and thrombosis and treatment].
Topics: Adult; Coronary Artery Disease; Coronary Thrombosis; Female; Homocysteine; Homocystinuria; Humans; Male; Methionine; Middle Aged; Peripheral Vascular Diseases; Pregnancy; Thrombophlebitis; Vitamins | 1997 |
Prevention of neural tube defects: vitamins, enzymes and genes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Inositol; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Neurologic Mutants; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Vitamins | 1998 |
Inherited thrombophilia and pregnancy.
Topics: Biomarkers; Female; Homocysteine; Humans; Pregnancy; Pregnancy Complications; Protein C; Risk; Risk Factors; Thrombophilia | 1998 |
Inherited hypercoagulable states.
Topics: Antithrombin III Deficiency; Blood Coagulation Disorders; Female; Fibrinogen; Fibrinolysis; Genetic Variation; Homocysteine; Humans; Male; Mutation; Pregnancy; Protein C; Prothrombin; Risk Factors; Thromboembolism | 1997 |
From birth to conception. Open or closed.
Topics: Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Netherlands; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Spinal Dysraphism | 1998 |
Open or closed? A world of difference: a history of homocysteine research.
Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Metabolism, Inborn Errors; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Vascular Diseases | 1998 |
Folic acid, homocysteine and one-carbon metabolism: a review of the essential biochemistry.
Topics: Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Vitamin B 12 Deficiency | 1998 |
[Folic acid protects against neural tube defects. But how many women of reproductive age have been informed about this fact?].
Topics: Female; Folic Acid; Guidelines as Topic; Health Education; Homocysteine; Humans; Multicenter Studies as Topic; Neural Tube Defects; Nutritional Requirements; Pregnancy; Primary Prevention | 1999 |
Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review.
Topics: Abortion, Habitual; Abortion, Spontaneous; Abruptio Placentae; Female; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Infarction; Odds Ratio; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors | 1999 |
Folate and oral clefts: where do we go from here? New directions in oral clefts research.
Topics: Cleft Lip; Cleft Palate; Female; Folic Acid; Genetic Variation; Homocysteine; Humans; Infant, Newborn; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Pregnancy | 1999 |
Folic acid: influence on the outcome of pregnancy.
Topics: Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Pregnancy; Pregnancy Outcome | 2000 |
Hyperhomocysteinaemia.
Topics: Animals; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Pregnancy; Risk Factors; Thrombophilia; Thrombosis; Vascular Diseases; Vitamin B Complex | 1999 |
Maternal folate status and lactation.
Topics: Animals; Animals, Suckling; Arteriosclerosis; Disease Susceptibility; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Infant, Newborn; Iron Deficiencies; Lactation; Mammals; Milk; Neoplasms; Neural Tube Defects; Neutrophils; Nutritional Requirements; Pregnancy; Pregnancy Complications; Pteroylpolyglutamic Acids; Rats | 1997 |
Homocysteine, folate enzymes and neural tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Pregnancy Complications; Vitamin B 12 | 1999 |
Hyperhomocysteinemia and thrombosis.
Topics: Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Male; Pregnancy; Risk Factors; Thrombosis | 2000 |
[The importance of folic acid in current medicine].
Topics: Adult; Cardiovascular Diseases; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Homocysteine; Humans; Infant; Infant, Newborn; Neural Tube Defects; Pregnancy | 2000 |
Homocysteine and cardiovascular disease: dietary supplements for all.
Topics: Cardiovascular Diseases; Congenital Abnormalities; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Nutritional Status; Pregnancy; Risk Factors | 2000 |
Biological and environmental determinants of plasma homocysteine.
Topics: Adult; Aged; Aging; Alcohol Drinking; Child; Cystathionine beta-Synthase; Diagnosis-Related Groups; Dietary Proteins; Endocrine System Diseases; Female; Folic Acid Antagonists; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Inflammation; Intestinal Diseases; Life Style; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Niacin; Nitrous Oxide; Norway; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Renal Insufficiency; Smoking; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Hyperhomocysteinemia and pregnancy--review of our present understanding and therapeutic implications.
Topics: Abortion, Habitual; Anticoagulants; Female; Fetal Death; Fetal Growth Retardation; Homocysteine; Humans; Neural Tube Defects; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Venous Thrombosis | 2000 |
[Homocysteine and pregnancy].
Topics: Biomarkers; Female; Homocysteine; Humans; Hyperhomocysteinemia; Pregnancy; Pregnancy Complications; Risk Factors; Thrombosis | 2000 |
Folic acid and neural tube defects.
Topics: Biological Availability; Diet; Dose-Response Relationship, Drug; England; Female; Flour; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Myocardial Ischemia; Neural Tube Defects; Nutritive Value; Pregnancy; Pregnancy Complications; Prevalence; Risk Factors; Wales | 2001 |
Genes, folate and homocysteine in embryonic development.
Topics: Animals; Dietary Supplements; Embryonic and Fetal Development; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy | 2001 |
Folate, homocysteine and neural tube defects: an overview.
Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Intestinal Absorption; Methylenetetrahydrofolate Reductase (NADPH2); Models, Chemical; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Prevalence | 2001 |
Roles of homocysteine in cell metabolism: old and new functions.
Topics: Cardiovascular Diseases; Cell Physiological Phenomena; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nervous System Malformations; Pregnancy; Pregnancy Complications; RNA, Transfer, Amino Acyl; S-Adenosylmethionine | 2001 |
Folate, vitamin B12 and homocysteine in relation to birth defects and pregnancy outcome.
Topics: Congenital Abnormalities; Deficiency Diseases; Developing Countries; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Importance of folate in human nutrition.
Topics: Biological Availability; Birth Weight; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; India; Intestinal Absorption; Liver; Male; Meat; Neoplasms; Neural Tube Defects; Nutrition Policy; Nutritional Physiological Phenomena; Pregnancy; Prevalence; Public Health; Vegetables | 2001 |
The importance of hyperhomocysteinemia as a risk factor for diseases: an overview.
Topics: Diet, Vegetarian; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Methylation; Models, Biological; Models, Chemical; Pregnancy; Risk Factors; Vascular Diseases; Vitamin B 12 Deficiency | 2001 |
Hyperhomocysteinaemia and human reproduction.
Topics: Abortion, Spontaneous; Chromosome Aberrations; Congenital Abnormalities; Family Health; Female; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Mutation; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors | 2001 |
Folic acid: are current fortification levels adequate?
Topics: Biomarkers; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Pregnancy; Safety; Treatment Outcome; United States | 2001 |
Current progress in early pregnancy investigation.
Topics: Abortion, Habitual; Abortion, Spontaneous; Chorionic Gonadotropin; Corpus Luteum; Factor V; Female; Fertilization in Vitro; Fibrinolytic Agents; Folic Acid; Glutathione S-Transferase pi; Glutathione Transferase; Homocysteine; Humans; Isoenzymes; Luteinizing Hormone; Nausea; Placentation; Platelet Aggregation; Point Mutation; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Sperm Injections, Intracytoplasmic; Vomiting | 2001 |
Folate bioavailability and health.
Topics: Biological Availability; Cardiovascular Diseases; Dietary Supplements; Female; Folic Acid; Food, Fortified; Hematinics; Homocysteine; Humans; Intestinal Absorption; Mental Disorders; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Pregnancy | 2002 |
Homocysteine as a risk factor in cardiovascular disease.
Topics: Biomarkers; Cardiovascular Diseases; Female; Homocysteine; Humans; Male; Pregnancy; Risk Factors | 2001 |
Intrauterine growth restriction.
Topics: Blood Flow Velocity; Female; Fetal Growth Retardation; Fetal Weight; Gestational Age; Growth Substances; Homocysteine; Humans; Inflammation; Placental Circulation; Pregnancy; Ultrasonography, Doppler; Ultrasonography, Prenatal; Umbilical Arteries | 2002 |
Manipulating the sulfur amino acid content of the early diet and its implications for long-term health.
Topics: Amino Acids, Sulfur; Animals; Dietary Proteins; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Homocysteine; Humans; Methionine; Nutritional Requirements; Pregnancy; Prenatal Exposure Delayed Effects; Protein Deficiency; Rats | 2002 |
Folic acid intake and its effects on the prevention of neural tube defects, the masking of vitamin B12 deficiency and the reduction of homocysteine.
Topics: Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Neural Tube Defects; Oklahoma; Pregnancy; Prenatal Care; Primary Prevention; Risk Assessment; United States; United States Food and Drug Administration; Vitamin B 12 Deficiency | 2002 |
Folic acid and prevention of birth defects.
Topics: Absorption; Adult; Congenital Abnormalities; Dietary Supplements; Drug Interactions; Female; Folic Acid; Hematinics; Homocysteine; Humans; Infant, Newborn; Nutritional Physiological Phenomena; Preconception Care; Pregnancy; Risk Factors | 2002 |
[Diagnosis and management of the aminoacidopathies (author's transl)].
Topics: Amino Acid Metabolism, Inborn Errors; Citric Acid Cycle; Female; Genotype; Homocysteine; Humans; Lysine; Phenylalanine; Pregnancy; Prenatal Diagnosis | 1978 |
39 trial(s) available for homocysteine and Pregnancy
| Article | Year |
|---|---|
Maternal choline supplementation alters vitamin B-12 status in human and murine pregnancy.
Topics: Adult; Animals; Betaine-Homocysteine S-Methyltransferase; Choline; Choline Dehydrogenase; Dietary Supplements; Female; Gene Expression Regulation; Homeodomain Proteins; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Mice, Mutant Strains; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Trimester, Third; Transcription Factors; Vitamin B 12; Young Adult | 2019 |
The effect of folic acid throughout pregnancy among pregnant women at high risk of pre-eclampsia: A randomized clinical trial.
Topics: Adult; Apgar Score; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Pre-Eclampsia; Pregnancy; Secondary Prevention; Vitamin B Complex | 2020 |
Association of antenatal vitamin B complex supplementation with neonatal vitamin B
Topics: China; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Pregnancy; Vitamin B 12; Vitamin B Complex | 2021 |
Cobalamin and folate status in women during early pregnancy in Bhaktapur, Nepal.
Topics: Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Nepal; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
The effects of high and low doses of folic acid on oxidation of protein levels during pregnancy: a randomized double-blind clinical trial.
Topics: Adult; Antioxidants; Biomarkers; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Oxidation-Reduction; Oxidative Stress; Pregnancy; Proteins; Young Adult | 2017 |
Maternal methyl donor supplementation during gestation counteracts bisphenol A-induced oxidative stress in sows and offspring.
Topics: Actins; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Benzhydryl Compounds; Betaine; Catalase; Choline; Diet; Dietary Supplements; Female; Folic Acid; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Malondialdehyde; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Phenols; Placenta; Pregnancy; Superoxide Dismutase; Swine; Vitamin B 12 | 2018 |
Vitamin B12 and homocysteine status during pregnancy in the metformin in gestational diabetes trial: responses to maternal metformin compared with insulin treatment.
Topics: Adult; Biomarkers; Cohort Studies; Diabetes, Gestational; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Metformin; Nutritional Status; Postpartum Period; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnancy Trimester, Third; South Australia; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Impact of continuing folic acid after the first trimester of pregnancy: findings of a randomized trial of Folic Acid Supplementation in the Second and Third Trimesters.
Topics: Adolescent; Adult; Dietary Supplements; Double-Blind Method; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Neural Tube Defects; Northern Ireland; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Young Adult | 2013 |
The importance of the one carbon cycle nutritional support in human male fertility: a preliminary clinical report.
Topics: Acetylcysteine; Adult; Birth Rate; Dietary Supplements; Embryo Implantation; Family Characteristics; Female; Fertilization in Vitro; Fruit; Homocysteine; Humans; Infertility, Male; Insemination, Artificial, Homologous; Male; Middle Aged; Opuntia; Plant Extracts; Pregnancy; Pregnancy Rate; Switzerland; Vitamin B Complex; Vitamin E; Zinc | 2014 |
Homocysteine metabolism, growth performance, and immune responses in suckling and weanling piglets.
Topics: Age Factors; Animals; Cell Proliferation; Concanavalin A; Diet; Female; Homocysteine; Interleukin-8; Lactation; Lymphocytes; Pregnancy; Sus scrofa; Swine; Vitamin B 12; Weaning | 2015 |
Vitamin B12 supplementation during pregnancy and postpartum improves B12 status of both mothers and infants but vaccine response in mothers only: a randomized clinical trial in Bangladesh.
Topics: Adolescent; Adult; Bangladesh; Biomarkers; C-Reactive Protein; Dietary Supplements; Dose-Response Relationship, Drug; Female; Ferritins; Folic Acid; Hemoglobins; Homocysteine; Humans; Immunoglobulin A; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Lactation; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Milk, Human; Orosomucoid; Postpartum Period; Pregnancy; Receptors, Transferrin; Vitamin B 12; Young Adult | 2016 |
Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes.
Topics: Adult; Biomarkers; Breast Feeding; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Energy Intake; Female; Healthy Volunteers; Homocysteine; Humans; Lactation; Methylmalonic Acid; Micronutrients; Postpartum Period; Pregnancy; Recommended Dietary Allowances; Vitamin B 12; Young Adult | 2015 |
Does preeclampsia have any adverse effect on fetal heart?
Topics: Adult; Biomarkers; Cross-Sectional Studies; Female; Fetal Blood; Fetal Heart; Homocysteine; Humans; Natriuretic Peptide, Brain; Peptide Fragments; Pre-Eclampsia; Pregnancy; Prospective Studies; Severity of Illness Index; Troponin I | 2016 |
Methyltetrahydrofolate vs Folic Acid Supplementation in Idiopathic Recurrent Miscarriage with Respect to Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms: A Randomized Controlled Trial.
Topics: Abortion, Habitual; Adult; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Iran; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Tetrahydrofolates; Young Adult | 2015 |
The Effect of High Dose Folic Acid throughout Pregnancy on Homocysteine (Hcy) Concentration and Pre-Eclampsia: A Randomized Clinical Trial.
Topics: Adult; Demography; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Linear Models; Pre-Eclampsia; Pregnancy; Pregnancy Outcome | 2016 |
Effects of maternal vitamin B12 supplementation on early infant neurocognitive outcomes: a randomized controlled clinical trial.
Topics: Adult; Brain; Child Development; Cognition; Dietary Supplements; Double-Blind Method; Female; Fetal Development; Homocysteine; Humans; India; Infant; Linear Models; Maternal Nutritional Physiological Phenomena; Micronutrients; Nutritional Status; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Socioeconomic Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2017 |
Comparison study on the effect of prenatal administration of high dose and low dose folic acid.
Topics: Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, First; Single-Blind Method | 2009 |
The effect of serum and intrafollicular insulin resistance parameters and homocysteine levels of nonobese, nonhyperandrogenemic polycystic ovary syndrome patients on in vitro fertilization outcome.
Topics: Adult; Biomarkers; Body Mass Index; Cross-Sectional Studies; Female; Fertilization in Vitro; Homocysteine; Humans; Hyperandrogenism; Ideal Body Weight; Infertility; Insulin Resistance; Male; Obesity; Ovarian Follicle; Polycystic Ovary Syndrome; Pregnancy; Prognosis; Treatment Outcome; Young Adult | 2010 |
Analysis of perinatal outcome by combination of first trimester maternal plasma homocysteine with uterine artery Doppler velocimetry.
Topics: Adult; Biomarkers; Blood Flow Velocity; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Premature Birth; Prognosis; Prospective Studies; Rheology; Ultrasonography, Prenatal; Uterine Artery; Vitamin B 12 | 2011 |
Effects of folic acid and vitamin B12 supplements on folate and homocysteine metabolism in pigs during early pregnancy.
Topics: Animal Nutritional Physiological Phenomena; Animals; Dietary Supplements; Female; Folic Acid; Homocysteine; Parity; Pregnancy; Pregnancy, Animal; Swine; Uterus; Vitamin B 12 | 2002 |
Higher homocysteine concentrations in women undergoing caesarean section under general anesthesia.
Topics: Adult; Anesthesia, Obstetrical; Cesarean Section; Female; Fetal Blood; Homocysteine; Humans; Maternal-Fetal Exchange; Natural Childbirth; Pregnancy; Risk Assessment | 2003 |
Effect of supplementation with folic acid throughout pregnancy on plasma homocysteine concentration.
Topics: Adult; Dietary Supplements; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Longitudinal Studies; Neural Tube Defects; Pregnancy; Treatment Outcome | 2004 |
Evaluation of a shorter methionine loading test.
Topics: Administration, Oral; Adult; Cardiovascular Diseases; Chelating Agents; Edetic Acid; Fasting; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pre-Eclampsia; Pregnancy; Risk Factors; Time Factors | 2004 |
Biochemical indexes of the B vitamins in cord serum are predicted by maternal B vitamin status.
Topics: Adult; Female; Fetal Blood; Gestational Age; Homocysteine; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Methylmalonic Acid; Nutritional Status; Predictive Value of Tests; Pregnancy; Vitamin B Complex | 2005 |
Effect of time of initiation and dose of prenatal iron and folic acid supplementation on iron and folate nutriture of Korean women during pregnancy.
Topics: Adult; Analysis of Variance; Anemia, Iron-Deficiency; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Iron, Dietary; Korea; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Prenatal Nutritional Physiological Phenomena; Time Factors | 2005 |
Oral N-acetylcysteine administration does not stabilise the process of established severe preeclampsia.
Topics: Acetylcysteine; Administration, Oral; Adult; Antioxidants; Double-Blind Method; Female; Free Radical Scavengers; Glutathione; HELLP Syndrome; Homocysteine; Humans; Oxidative Stress; Pre-Eclampsia; Pregnancy; Regression Analysis; Treatment Outcome | 2006 |
Combining mid-trimester maternal plasma homocysteine with uterine artery doppler velocimetry: is it useful?
Topics: Adolescent; Adult; Arteries; Female; Homocysteine; Humans; Mass Screening; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Second; Prospective Studies; Rheology; Ultrasonography; Uterus | 2007 |
Fortified mineral water improves folate status and decreases plasma homocysteine concentration in pregnant women.
Topics: Adult; Calcium; Dietary Supplements; Double-Blind Method; Female; Finland; Folic Acid; Homocysteine; Humans; Mineral Waters; Pregnancy; Prenatal Care; Vitamin B 12; Vitamin B 6; Vitamin D | 2007 |
Homocysteine levels are unaffected by metformin treatment in both nonpregnant and pregnant women with polycystic ovary syndrome.
Topics: Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Methylenetetrahydrofolate Reductase (NADPH2); Polycystic Ovary Syndrome; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Prospective Studies; Testosterone; Vitamin B 12 | 2007 |
Neural tube defects and elevated homocysteine levels in amniotic fluid.
Topics: Adult; Amniotic Fluid; Female; Fetal Diseases; Folic Acid; Gestational Age; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pregnancy Trimester, Second; Pyridoxine; Vitamin B 12 | 1995 |
Hyperhomocysteinemia--a risk factor for abruptio placentae.
Topics: Abruptio Placentae; Adult; Cystathionine beta-Synthase; Erythrocytes; Female; Homocysteine; Humans; Pregnancy; Risk Factors; Vitamins | 1997 |
Plasma homocyst(e)ine concentrations in pregnant and nonpregnant women with controlled folate intake.
Topics: Adolescent; Adult; Female; Folic Acid; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, Second | 1998 |
Effects of folic acid and vitamin B6 supplementation on women with hyperhomocysteinemia and a history of preeclampsia or fetal growth restriction.
Topics: Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Medical History Taking; Methionine; Pre-Eclampsia; Pregnancy; Pyridoxine; Statistics, Nonparametric | 1998 |
Elevated second-trimester serum homocyst(e)ine levels and subsequent risk of preeclampsia.
Topics: Adult; Body Mass Index; Female; Homocysteine; Humans; Maternal Age; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Second; Risk Factors; Socioeconomic Factors | 1999 |
Hyperhomocysteinemia and other thrombotic risk factors in women with placental vasculopathy.
Topics: Activated Protein C Resistance; Adult; Antithrombin III; Case-Control Studies; Factor V; Female; Homocysteine; Humans; Hyperhomocysteinemia; Mutation; Placenta; Placenta Diseases; Pregnancy; Protein C; Protein S; Risk Factors; Tetrahydrofolates; Thrombosis | 2000 |
Second-trimester plasma homocysteine levels and pregnancy-induced hypertension, preeclampsia, and intrauterine growth restriction.
Topics: Adult; Erythrocytes; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Hypertension; Osmolar Concentration; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Reference Values; Zinc | 2000 |
Vitamin supplementation and pregnancy outcome in women with recurrent early pregnancy loss and hyperhomocysteinemia.
Topics: Abortion, Habitual; Adult; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Infant, Premature; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Pyridoxine; Vitamin E | 2001 |
Determinants of cobalamin status in newborns.
Topics: Adult; Biomarkers; Female; Homocysteine; Humans; Infant, Newborn; Logistic Models; Maternal-Fetal Exchange; Methylmalonic Acid; Parity; Pregnancy; Reference Values; Vitamin B 12 | 2001 |
The C677T polymorphism of the methylenetetrahydrofolate reductase gene and idiopathic recurrent miscarriage.
Topics: Abortion, Habitual; Adult; Aged; Aged, 80 and over; Female; Gene Frequency; Genotype; Heterozygote; Homocysteine; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Pregnancy; White People | 2002 |
652 other study(ies) available for homocysteine and Pregnancy
| Article | Year |
|---|---|
Vitamin B12, folate and homocysteine concentrations during pregnancy and early signs of atherosclerosis at school-age.
Topics: Adult; Atherosclerosis; Cardiometabolic Risk Factors; Carotid Intima-Media Thickness; Child; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Male; Maternal Exposure; Maternal Nutritional Physiological Phenomena; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Vitamin B 12 | 2021 |
Periconceptional maternal and paternal homocysteine levels and early utero-placental (vascular) growth trajectories: The Rotterdam periconception cohort.
Topics: Adult; Cohort Studies; Fathers; Female; Fertilization; Fertilization in Vitro; Fetal Development; Homocysteine; Humans; Male; Mothers; Netherlands; Placenta; Placental Circulation; Placentation; Pregnancy; Pregnancy Trimester, First; Ultrasonography, Prenatal; Uterus | 2021 |
Imbalanced Folate and Vitamin B12 in the Third Trimester of Pregnancy and its Association with Birthweight and Child Growth up to 2 Years.
Topics: Birth Weight; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Vitamin B 12 | 2022 |
Dietary Intake of Folate and Assessment of the Folate Deficiency Prevalence in Slovenia Using Serum Biomarkers.
Topics: Adolescent; Adult; Aged; Biomarkers; Child; Diet; Eating; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pregnancy; Pregnancy Complications; Prevalence; Propensity Score; Slovenia; Young Adult | 2021 |
5-Methyltetrahydrofolate and Vitamin B12 Supplementation Is Associated with Clinical Pregnancy and Live Birth in Women Undergoing Assisted Reproductive Technology.
Topics: Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Infertility, Female; Live Birth; Pregnancy; Reproductive Techniques, Assisted; Retrospective Studies; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex | 2021 |
Polymorphisms in vitamin B12 and folate metabolising genes and their association with adverse pregnancy outcome: secondary analysis of a population based case control study.
Topics: Case-Control Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Infant; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Pregnancy Outcome; Premature Birth; Vitamin B 12 | 2022 |
One-carbon metabolism during the menstrual cycle and pregnancy.
Topics: Carbon; Estradiol; Female; Folic Acid; Homocysteine; Humans; Menstrual Cycle; Pregnancy; S-Adenosylmethionine; Vitamin B 12 | 2021 |
Physiologically relevant hCys concentrations mobilize MeHg from rabbit serum albumin to form MeHg-hCys complexes.
Topics: Animals; Female; Homocysteine; Mercury; Methylmercury Compounds; Placenta; Pregnancy; Rabbits; Serum Albumin; Sulfhydryl Compounds | 2022 |
The Role of High Concentrations of Homocysteine for the Development of Fetal Growth Restriction.
Topics: Female; Fetal Growth Retardation; Homocysteine; Humans; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Prospective Studies; ROC Curve; Ultrasonography, Prenatal | 2022 |
Folic Acid Supplementation in Early Pregnancy, Homocysteine Concentration, and Risk of Gestational Diabetes Mellitus.
Topics: Diabetes, Gestational; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Pregnancy; Prospective Studies | 2022 |
Estimation of homocysteine concentration as an indicator of foetal death in pregnant Chinese women with preeclampsia: A case-control study.
Topics: Case-Control Studies; China; Female; Fetal Death; Homocysteine; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnant Women | 2022 |
RBC Folate and Serum Folate, Vitamin B-12, and Homocysteine in Chinese Couples Prepregnancy in the Shanghai Preconception Cohort.
Topics: Biomarkers; China; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Folate metabolism abnormalities in infertile patients with endometriosis.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Endometriosis; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy | 2022 |
First Trimester Maternal Homocysteine and Embryonic and Fetal Growth: The Rotterdam Periconception Cohort.
Topics: Female; Fetal Development; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Ultrasonography, Prenatal | 2022 |
Study on the correlation between homocysteine-related dietary patterns and gestational diabetes mellitus:a reduced-rank regression analysis study.
Topics: Diabetes, Gestational; Diet; Fasting; Female; Homocysteine; Humans; Pregnancy; Regression Analysis; Risk Factors | 2022 |
Factors associated with fetal karyotype in spontaneous abortion: a case-case study.
Topics: Abortion, Spontaneous; Chromosome Aberrations; Female; Homocysteine; Humans; In Situ Hybridization, Fluorescence; Karyotype; Karyotyping; Pregnancy; Tandem Mass Spectrometry | 2022 |
Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats.
Topics: Animals; Anxiety; Cortical Excitability; Female; Homocysteine; Hyperalgesia; Hyperhomocysteinemia; Migraine Disorders; Nitroglycerin; Photophobia; Pregnancy; Rats | 2022 |
Pregnancy homocysteine and cobalamin status predict childhood metabolic health in the offspring.
Topics: Birth Weight; Child; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Pregnancy; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
Association of MTHFR 677C>T polymorphism with pregnancy outcomes in IVF/ICSI-ET recipients with adequate synthetic folic acid supplementation.
Topics: Embryo Transfer; Female; Fertilization in Vitro; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Pregnancy Outcome; Premature Birth; Retrospective Studies; Semen; Sperm Injections, Intracytoplasmic | 2022 |
Fetal hyperhomocysteinemia is associated with placental inflammation and early breakdown of maternal-fetal tolerance in pre-term birth.
Topics: Biomarkers; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Placenta; Pregnancy; Premature Birth; Term Birth; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vitamin B 12 | 2022 |
Comparison of the Levels of Blood Homocysteine between Women with Unexplained Infertility and Normal Fertility.
Topics: Cross-Sectional Studies; Female; Fertility; Homocysteine; Humans; Hyperhomocysteinemia; Infertility, Female; Pregnancy | 2022 |
Association of methylenetetrahydrofolate reductase
Topics: Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; India; Infant, Newborn; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Parturition; Polymorphism, Genetic; Pregnancy; Pregnant Women; Premature Birth; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Maternal serum concentrations of one-carbon metabolism factors modify the association between biomarkers of arsenic methylation efficiency and birth weight.
Topics: Adult; Arsenic; Arsenicals; Biomarkers; Birth Weight; Carbon; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12 | 2022 |
Effect of Blood Homocysteine on the Outcome of Artificial Insemination in Women with Polycystic Ovary Syndrome.
Topics: Female; Homocysteine; Humans; Infertility, Female; Insemination, Artificial; Male; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy | 2022 |
Elevated homocysteine activates unfolded protein responses and causes aberrant trophoblast differentiation and mouse blastocyst development.
Topics: Animals; Blastocyst; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Placenta; Pregnancy; Trophoblasts; Unfolded Protein Response; Vitamins | 2022 |
Maternal Vitamin B
Topics: Child; Female; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Neonatal Screening; Pregnancy; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
High-protein nutrition during pregnancy increases neuroinflammation and homocysteine levels and impairs behavior in male adolescent rats offspring.
Topics: Animals; Anxiety; Diet; Female; Homocysteine; Humans; Male; Neuroinflammatory Diseases; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Rats | 2022 |
Acquired Vitamin B12 Deficiency in Newborns: Positive Impact on Newborn Health through Early Detection.
Topics: Biomarkers; Early Diagnosis; Female; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant Health; Infant, Newborn; Male; Methylmalonic Acid; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Pre-natal dietary imbalance of folic acid and vitamin B12 deficiency adversely impacts placental development and fetal growth.
Topics: Animals; Diet; Female; Fetal Development; Fetal Weight; Folic Acid; Homocysteine; Mice; Placenta; Placentation; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank.
Topics: Biological Specimen Banks; Biomarkers; Female; Folic Acid; Homocysteine; Humans; Mendelian Randomization Analysis; Pregnancy; United Kingdom; Vitamin A; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin K | 2023 |
Study on the predictive value of serum hypersensitive C-reactive protein, homocysteine, fibrinogen, and omentin-1 levels with gestational diabetes mellitus.
Topics: Blood Glucose; C-Reactive Protein; Case-Control Studies; Cholesterol, HDL; Diabetes, Gestational; Female; Fibrinogen; Homocysteine; Humans; Infant; Pregnancy | 2023 |
Vitamin B6 Levels and Impaired Folate Status but Not Vitamin B12 Associated with Low Birth Weight: Results from the MAASTHI Birth Cohort in South India.
Topics: Birth Cohort; Birth Weight; Female; Folic Acid; Homocysteine; Humans; India; Infant, Low Birth Weight; Infant, Newborn; Pregnancy; Prospective Studies; Pyridoxine; Vitamin B 12; Vitamin B 6 | 2023 |
Serum 5-Methyltetrahydrofolate Status Is Associated with One-Carbon Metabolism-Related Metabolite Concentrations and Enzyme Activity Indicators in Young Women.
Topics: Adolescent; Adult; Betaine; Carbon; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Pregnancy; S-Adenosylmethionine; Young Adult | 2023 |
Trimester-specific reference intervals of serum homocysteine levels for pregnant women: a longitudinal study in China.
Topics: China; Female; Homocysteine; Humans; Longitudinal Studies; Pregnancy; Pregnancy Trimesters; Reference Values | 2023 |
Discrimination of blood metabolomics profiles in neonates with idiopathic polyhydramnios.
Topics: Alanine; Asparagine; Aspartic Acid; Cesarean Section; Child; Chromatography, Liquid; Female; Glutamates; Homocysteine; Humans; Infant, Newborn; Phenylalanine; Polyhydramnios; Pregnancy; RNA, Transfer; Serine; Tandem Mass Spectrometry | 2023 |
Impact of Homocysteine as a Preconceptional Screening Factor for In Vitro Fertilization and Prevention of Miscarriage with Folic Acid Supplementation Following Frozen-Thawed Embryo Transfer: A Hospital-Based Retrospective Cohort Study.
Topics: Abortion, Spontaneous; Cross-Sectional Studies; Dietary Supplements; Embryo Transfer; Female; Fertilization in Vitro; Folic Acid; Homocysteine; Hospitals; Humans; Infant, Newborn; Infertility, Female; Male; Pregnancy; Retrospective Studies; Semen | 2023 |
High prevalence of chronic endometritis is associated with metabolic abnormality and reduced live birth rate among IVF women with non-uniform endometrial echogenicity.
Topics: Birth Rate; Chronic Disease; Endometritis; Female; Fertilization in Vitro; Homocysteine; Humans; Infertility, Female; Pregnancy; Prevalence; Retrospective Studies; Ultrasonography | 2023 |
The importance of preconception Hcy testing: identification of a folate trap syndrome in a woman attending an assisted reproduction program.
Topics: Female; Folic Acid; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Reproduction; S-Adenosylmethionine | 2023 |
Methodological challenges in using human umbilical artery as a model for in vitro studies.
Topics: Acetylcholine; Adenosine Triphosphate; Female; Homocysteine; Humans; Minoxidil; Phenylephrine; Pre-Eclampsia; Pregnancy; Serotonin; Umbilical Arteries; Vasoconstrictor Agents; Vasodilation | 2023 |
[Association between maternal plasma one-carbon biomarkers during pregnancy and fetal growth in twin pregnancies].
Topics: Adult; Betaine; Biomarkers; Birth Weight; Choline; Cohort Studies; Female; Fetal Development; Fetal Weight; Homocysteine; Humans; Infant, Newborn; Methionine; Pregnancy; Pregnancy Outcome; Pregnancy Trimesters; Pregnancy, Twin | 2023 |
CARDIOVASCULAR RISK IN WOMEN WITH PREECLAMPSIA.
Topics: Cardiovascular Diseases; Female; Heart Disease Risk Factors; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Prospective Studies; Risk Factors | 2022 |
Serum homocysteine and vitamin B12 levels in women with gestational diabetes mellitus.
Topics: Adult; Blood Glucose; Body Mass Index; Case-Control Studies; Diabetes, Gestational; Female; Glucose Tolerance Test; Glycated Hemoglobin; Homocysteine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Pregnancy; Prospective Studies; Vitamin B 12; Young Adult | 2019 |
Serum Betaine and Dimethylglycine Are Higher in South Asian Compared with European Pregnant Women in Canada, with Betaine and Total Homocysteine Inversely Associated in Early and Midpregnancy, Independent of Ethnicity.
Topics: Adult; Betaine; Canada; Ethnicity; Europe; Female; Homocysteine; Humans; India; Pregnancy; Retrospective Studies; Sarcosine | 2019 |
Prenatal folate, homocysteine and vitamin B
Topics: Brain; Child; Child Behavior Disorders; Cognition Disorders; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Language Development Disorders; Magnetic Resonance Imaging; Male; Netherlands; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Maternal BMI and nutritional status in early pregnancy and its impact on neonatal outcomes at birth in Bangladesh.
Topics: Bangladesh; Biomarkers; Birth Weight; Body Mass Index; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Newborn; Male; Maternal Health; Nutritional Status; Pregnancy; Pregnancy Complications, Hematologic; Prognosis; Prospective Studies; Young Adult | 2019 |
Association of vitamin D with fatty acids in pregnancy.
Topics: Adolescent; Adult; Case-Control Studies; Cross-Sectional Studies; Erythrocytes; Fatty Acids, Monounsaturated; Female; Fetal Blood; Homocysteine; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Vitamin D; Young Adult | 2020 |
Effect of imbalance in folate and vitamin B12 in maternal/parental diet on global methylation and regulatory miRNAs.
Topics: Animals; Brain; Carrier Proteins; Diet; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Fetal Growth Retardation; Fetus; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Developmental; Homocysteine; Kidney; Liver; Male; Maternal Exposure; Mice; Mice, Inbred C57BL; MicroRNAs; Paternal Exposure; Placenta; Pregnancy; Pregnancy Complications; Reverse Transcriptase Polymerase Chain Reaction; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Homocysteine-mediated gender-dependent effects of prenatal maternal depression on motor development in newborn infants.
Topics: Adult; Depression; Female; Homocysteine; Humans; Infant; Infant, Newborn; Male; Mothers; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Vitamins | 2020 |
Reduced serum concentrations of vitamin B
Topics: Adult; Cross-Sectional Studies; Diabetes, Gestational; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, First; Saudi Arabia; Thyrotropin; Vitamin B 12; Vitamins | 2019 |
Organochlorine pesticides exposure may disturb homocysteine metabolism in pregnant women.
Topics: China; DDT; Environmental Monitoring; Female; Homocysteine; Humans; Hydrocarbons, Chlorinated; Pesticides; Pregnancy | 2020 |
Association between serum homocysteine level and unexplained infertility in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI): A retrospective, hospital-based, case-control study.
Topics: Adult; Case-Control Studies; Female; Fertilization in Vitro; Homocysteine; Hospitals; Humans; Infertility, Female; Male; Oocytes; Pregnancy; Pregnancy Outcome; Retrospective Studies; Sperm Injections, Intracytoplasmic | 2020 |
Trends of folate, vitamin B
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; India; Pregnancy; Pregnancy Outcome; Pregnancy Trimesters; Vitamin B 12; Vitamin B Complex; Young Adult | 2020 |
Evaluation of methylenetetrahydrofolate reductase (MTHFR) activity and the levels of homocysteine and malondialdehyde (MDA) in the serum of women with preeclampsia.
Topics: Adult; Blood Pressure; Case-Control Studies; Female; Homocysteine; Humans; Malondialdehyde; Methylenetetrahydrofolate Reductase (NADPH2); Pre-Eclampsia; Pregnancy; Young Adult | 2020 |
Serum homocysteine and folate concentrations in early pregnancy and subsequent events of adverse pregnancy outcome: the Sichuan Homocysteine study.
Topics: Adult; Case-Control Studies; China; Female; Folic Acid; Homocysteine; Humans; Infant, Low Birth Weight; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Premature Birth; Retrospective Studies; Risk Factors; Vitamin B 12 | 2020 |
The determinants of maternal homocysteine in pregnancy: findings from the Ottawa and Kingston Birth Cohort.
Topics: Canada; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy | 2020 |
Maternal B12, Folate and Homocysteine Concentrations and Offspring Cortisol and Cardiovascular Responses to Stress.
Topics: Adolescent; Adult; Cardiovascular System; Female; Folic Acid; Homocysteine; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Stress, Psychological; Vitamin B 12; Young Adult | 2020 |
Effects of MTHFR C677T polymorphism on vitamin D, homocysteine and natural killer cell cytotoxicity in women with recurrent pregnancy losses.
Topics: Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Killer Cells, Natural; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Retrospective Studies; Vitamin B 12; Vitamin D; Vitamins | 2020 |
Distribution of 5-Methyltetrahydrofolate and Folic Acid Levels in Maternal and Cord Blood Serum: Longitudinal Evaluation of Japanese Pregnant Women.
Topics: Adult; Asian People; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Japan; Longitudinal Studies; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnant Women; Prospective Studies; Tetrahydrofolates; Young Adult | 2020 |
Hydrogen Sulfide Alleviates Anxiety, Motor, and Cognitive Dysfunctions in Rats with Maternal Hyperhomocysteinemia via Mitigation of Oxidative Stress.
Topics: Animals; Anxiety; Cognitive Dysfunction; Cystathionine beta-Synthase; Female; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Oxidative Stress; Pregnancy; Pregnancy Complications; Rats; Reactive Oxygen Species; Treatment Outcome | 2020 |
Maternal folate, one-carbon metabolism and pregnancy outcomes.
Topics: Carbon; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Maternal Nutritional Physiological Phenomena; Pregnancy; Pregnancy Outcome; Premature Birth; Uterine Artery | 2021 |
Use of Plastics with Hot Food among Saudi Pregnant Women Is Associated with Increased Concentrations of A1C, Thyroid-Stimulating Hormone, and Homocysteine and Decreased Concentrations of Vitamins and Minerals.
Topics: Adult; Cross-Sectional Studies; Female; Glycated Hemoglobin; Homocysteine; Hot Temperature; Humans; Minerals; Plastics; Pregnancy; Prospective Studies; Saudi Arabia; Thyrotropin; Vitamins | 2020 |
The correlation between plasma total homocysteine level and gestational diabetes mellitus in a Chinese Han population.
Topics: Adult; Case-Control Studies; China; Diabetes, Gestational; Ethnicity; Female; Glucose Tolerance Test; Homocysteine; Humans; Insulin; Pregnancy | 2020 |
Study on Maternal SNPs of MTHFR Gene and HCY Level Related to Congenital Heart Diseases.
Topics: Adult; Case-Control Studies; Child; Female; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Mutation; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Surveys and Questionnaires; Young Adult | 2021 |
Cross-sectional association between vitamin B12 status and probable postpartum depression in Indian women.
Topics: Adolescent; Adult; Cesarean Section; Cross-Sectional Studies; Depression, Postpartum; Diet; Female; Homocysteine; Humans; India; Methylmalonic Acid; Pregnancy; Pregnancy, Unplanned; Risk Factors; S-Adenosylmethionine; Serotonin; Social Class; Tetrahydrofolates; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
Maternal vitamin B
Topics: Canada; Female; Homocysteine; Humans; Infant, Newborn; Mothers; Pregnancy; Premature Birth; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2021 |
Correlation of Homocysteine, AHSG, CRP with Insulin Resistance, 25-(OH)2-VitD, Blood Lipids in Gestational Diabetes Patients.
Topics: alpha-2-HS-Glycoprotein; Blood Glucose; Body Mass Index; C-Reactive Protein; Diabetes, Gestational; Female; Homocysteine; Humans; Insulin; Insulin Resistance; Lipids; Pregnancy | 2021 |
Value of amniotic fluid homocysteine assay in prenatal diagnosis of combined methylmalonic acidemia and homocystinuria, cobalamin C type.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Female; Homocysteine; Homocystinuria; Humans; Methylmalonic Acid; Oxidoreductases; Pregnancy; Prenatal Diagnosis; Reproducibility of Results; Retrospective Studies; Vitamin B 12 | 2021 |
Associations of Early Pregnancy and Neonatal Circulating Folate, Vitamin B-12, and Homocysteine Concentrations with Cardiometabolic Risk Factors in Children at 10 y of Age.
Topics: Cardiometabolic Risk Factors; Cardiovascular Diseases; Child; Female; Folic Acid; Glucose; Homocysteine; Humans; Infant, Newborn; Micronutrients; Overweight; Pregnancy; Prospective Studies; Risk Factors; Vitamin B 12; Vitamins | 2021 |
Maternal one carbon metabolism and interleukin-10 &-17 synergistically influence the mode of delivery in women with Early Onset Pre-Eclampsia.
Topics: Adult; Biomarkers; Case-Control Studies; Cesarean Section; Delivery, Obstetric; Female; Gestational Age; Homocysteine; Humans; Interleukin-10; Interleukin-17; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Premature Birth; Time Factors | 2021 |
Fetal Programming by Methyl Donor Deficiency Produces Pathological Remodeling of the Ascending Aorta.
Topics: Animal Nutritional Physiological Phenomena; Animals; Aorta; Aortic Diseases; Disease Models, Animal; Extracellular Matrix Proteins; Female; Fetal Development; Folic Acid Deficiency; Gene Expression Regulation, Developmental; Gestational Age; Homocysteine; Maternal Nutritional Physiological Phenomena; Peptide Hydrolases; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Vascular Remodeling; Vitamin B 12 Deficiency | 2021 |
Increased homocysteine mediated oxidative stress as key determinant of hepatitis E virus (HEV) infected pregnancy complication and outcome: A study from Northeast India.
Topics: Adult; Female; Hepatitis E; Hepevirus; Homocysteine; Humans; India; Oxidative Stress; Pregnancy; Pregnancy Complications, Infectious; Young Adult | 2021 |
Changes of Serum Sex Hormone-Binding Globulin, Homocysteine, and Hypersensitive CRP Levels during Pregnancy and Their Relationship with Gestational Diabetes Mellitus.
Topics: Adult; Biomarkers; C-Reactive Protein; Case-Control Studies; Diabetes, Gestational; Female; Gestational Age; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Sex Hormone-Binding Globulin | 2021 |
Associations of circulating folate, vitamin B12 and homocysteine concentrations in early pregnancy and cord blood with epigenetic gestational age: the Generation R Study.
Topics: Adult; Cohort Studies; Epigenesis, Genetic; Epigenomics; Female; Fetal Blood; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Newborn; Male; Pregnancy; Prospective Studies; Vitamin B 12 | 2021 |
Folate and vitamin B12 status: associations with maternal glucose and neonatal DNA methylation sites related to dysglycaemia, in pregnant women with obesity.
Topics: Diabetes, Gestational; DNA Methylation; Female; Folic Acid; Glucose; Homocysteine; Humans; Infant, Newborn; Obesity; Pregnancy; Pregnant Women; Vitamin B 12 | 2022 |
Different dietary combinations of folic acid and vitamin B12 in parental diet results in epigenetic reprogramming of IGF2R and KCNQ1OT1 in placenta and fetal tissues in mice.
Topics: Animals; Body Weight; Brain; Diet; Dose-Response Relationship, Drug; Drug Interactions; Epigenesis, Genetic; Female; Fetus; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Developmental; Genomic Imprinting; Homocysteine; Kidney; Liver; Male; Mice; Placenta; Pregnancy; Pregnancy Complications; Receptor, IGF Type 2; RNA, Long Noncoding; RNA, Messenger; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Association of homocysteine with IVF/ICSI outcomes stratified by MTHFR C677T polymorphisms: a prospective cohort study.
Topics: Adult; China; Female; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Ovulation Induction; Pregnancy; Pregnancy Outcome; Prospective Studies; Sperm Injections, Intracytoplasmic | 2021 |
Higher serum homocysteine and lower thyroid hormone levels in pregnant women are associated with neural tube defects.
Topics: Animals; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Mice; Neural Tube Defects; Pregnancy; Pregnant Women; Thyroid Hormones; Thyroxine | 2021 |
Laboratory characteristics analysis of the efficacy of levothyroxine on subclinical hypothyroidism during pregnancy: a single-center retrospective study.
Topics: Adult; Female; Homocysteine; Humans; Hypothyroidism; Lipoproteins; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies; Thyroxine; Treatment Outcome | 2021 |
Effect of nickel on red blood cell parameters and on serum vitamin B12, folate and homocysteine concentrations during pregnancy with and without anemia.
Topics: Anemia; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Nickel; Pregnancy; Vitamin B 12 | 2021 |
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Cells, Cultured; Female; Heart Defects, Congenital; Homocysteine; Humans; Microfilament Proteins; Pregnancy; Proteasome Endopeptidase Complex; Rats | 2017 |
mTOR folate sensing links folate availability to trophoblast cell function.
Topics: Cells, Cultured; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Pregnancy; Proton-Coupled Folate Transporter; Trophoblasts | 2017 |
High folate and low vitamin B12 status during pregnancy is associated with gestational diabetes mellitus.
Topics: Adult; China; Cohort Studies; Comorbidity; Cross-Sectional Studies; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; India; Malaysia; Male; Nutritional Status; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2018 |
Joint effect of maternal plasma homocysteine and prepregnancy obesity on child blood pressure: a prospective birth cohort study.
Topics: Adult; Biomarkers; Blood Pressure; Body Mass Index; Boston; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Male; Mothers; Obesity; Oxidative Stress; Preconception Care; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Risk Factors; Time Factors; Vitamin B 12 | 2017 |
Organic food consumption during pregnancy and its association with health-related characteristics: the KOALA Birth Cohort Study.
Topics: Biomarkers; Body Mass Index; Dairy Products; Diet, Healthy; Fatty Acids; Female; Food, Organic; Fruit; Homocysteine; Humans; Linoleic Acids, Conjugated; Meat; Micronutrients; Netherlands; Oleic Acid; Oleic Acids; Pregnancy; Principal Component Analysis; Prospective Studies; Socioeconomic Factors; Surveys and Questionnaires; Trans Fatty Acids; Vegetables; Vitamin D | 2017 |
Maternal serum homocysteine and uterine artery Doppler as predictors of preeclampsia and poor placentation.
Topics: Adult; Cohort Studies; Female; Fetal Growth Retardation; Homocysteine; Humans; Placentation; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Second; Prospective Studies; Ultrasonography, Doppler; Uterine Artery | 2017 |
The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations.
Topics: Abortion, Habitual; Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Pregnancy; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2017 |
An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Sequence; Cells, Cultured; Exons; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylation; Models, Molecular; Pregnancy; Pregnancy Complications; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Deletion; Spinal Dysraphism; Young Adult | 2017 |
Association of maternal serum homocysteine concentration levels in late stage of pregnancy with preterm births: a nested case-control study.
Topics: Adult; Birth Weight; Case-Control Studies; Female; Homocysteine; Humans; Infant, Newborn; Infant, Premature; Pregnancy; Premature Birth; Young Adult | 2018 |
Pregnant women of South Asian ethnicity in Canada have substantially lower vitamin B12 status compared with pregnant women of European ethnicity.
Topics: Adult; Asia; Asian People; Biomarkers; Canada; Europe; Female; Homocysteine; Humans; Pregnancy; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; White People; Young Adult | 2017 |
Different Effects of Maternal Low-Isoflavone Soy Protein and Genistein Consumption on Hepatic Lipid Metabolism of 21-Day-Old Male Rat Offspring.
Topics: Adiponectin; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Blood Glucose; Caseins; Cholesterol; Dietary Supplements; Fatty Acids, Nonesterified; Female; Genistein; Homocysteine; Insulin; Isoflavones; Lipid Metabolism; Liver; Male; Maternal Nutritional Physiological Phenomena; PPAR alpha; Pregnancy; Rats; Rats, Sprague-Dawley; Soybean Proteins; Triglycerides; Triiodothyronine | 2017 |
The Association of Thyroid Function With Maternal and Neonatal Homocysteine Concentrations.
Topics: Adult; Birth Weight; Cohort Studies; Dietary Supplements; Female; Fetal Blood; Folic Acid; Genetic Variation; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Prospective Studies; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Vitamin B 12; Vitamins | 2017 |
Association of serum asymmetric dimethylarginine, homocysteine, and l-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy.
Topics: Adult; Area Under Curve; Arginine; Biomarkers; Body Mass Index; Case-Control Studies; Female; Gestational Age; Homocysteine; Humans; Logistic Models; Nitric Oxide; Overweight; Parity; Pre-Eclampsia; Pregnancy; Risk Factors | 2017 |
Synergistic Toxicity of the Neurometabolites Quinolinic Acid and Homocysteine in Cortical Neurons and Astrocytes: Implications in Alzheimer's Disease.
Topics: Analysis of Variance; Animals; Annexin A5; Astrocytes; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Drug Synergism; Embryo, Mammalian; Female; Homocysteine; Membrane Potentials; Mitochondria; Nerve Tissue Proteins; Neurons; Neurotoxins; Pregnancy; Quinolinic Acid; Rats; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances | 2018 |
Correlation of Maternal Serum Homocysteine in the First Trimester with the Development of Gestational Hypertension and Preeclampsia.
Topics: Adult; Biomarkers; Blood Pressure; Body Mass Index; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Logistic Models; Odds Ratio; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Retrospective Studies; Risk Assessment; Risk Factors; Vitamin B 12 | 2017 |
Maternal serum homocysteine and uterine artery Doppler as predictors of preeclampsia and poor placentation.
Topics: Female; Homocysteine; Humans; Placentation; Pre-Eclampsia; Pregnancy; Ultrasonography, Doppler; Uterine Artery | 2018 |
Impact of distinct factors affecting serum homocysteine levels in preeclamptic women.
Topics: Case-Control Studies; Female; Homocysteine; Humans; Placentation; Pre-Eclampsia; Pregnancy; Uterine Artery | 2018 |
Homocysteine pathway and in vitro fertilization outcome.
Topics: Adolescent; Adult; Erythrocytes; Female; Fertilization in Vitro; Folic Acid; Homocysteine; Humans; Pregnancy; Pregnancy Rate; Prospective Studies; Vitamin B 12; Young Adult | 2018 |
Laparoscopic ovarian drilling reduces serum homocysteine levels in women with Polycystic Ovary Syndrome.
Topics: Adult; Cross-Sectional Studies; Female; Homocysteine; Humans; Infertility, Female; Laparoscopy; Ovary; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Rate; Treatment Outcome; Young Adult | 2018 |
Association between Maternal and Infantile Markers of Cobalamin Status During the First Month Post-Delivery.
Topics: Breast Feeding; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Infant, Newborn; Male; Pregnancy; Prenatal Exposure Delayed Effects; Turkey; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Genetic polymorphisms in folate metabolism as risk for Down syndrome in the southern China.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Asian People; Case-Control Studies; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Risk Factors; Young Adult | 2019 |
Early pregnancy folate-cobalamin interactions and their effects on cobalamin status and hematologic variables throughout pregnancy.
Topics: Adult; Anemia, Iron-Deficiency; Body Mass Index; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Iron, Dietary; Longitudinal Studies; Methylmalonic Acid; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prevalence; Socioeconomic Factors; Vitamin B 12 | 2018 |
The protective effect of polyunsaturated fatty acid intake during pregnancy against embryotoxicity of sodium valproate in mice.
Topics: Animals; Anticonvulsants; Embryonic Development; Fatty Acids, Omega-3; Female; Fetal Diseases; Folic Acid; Homocysteine; Humans; Male; Mice; Mice, Inbred ICR; Pregnancy; Pregnancy Complications; Seizures; Valproic Acid | 2018 |
[HYPERTENSION OF PREGNANCY ASSOCIATED WITH HYPERGOMOCYSTEINEMIA OF THE FIRST TRIMESTER OF PREGNANCY].
Topics: Adult; Eclampsia; Female; HELLP Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Pregnancy-Induced; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Prognosis; Prospective Studies | 2018 |
The assessment of maternal and umbilical cord homocysteine levels in obese pregnant women.
Topics: Adult; Birth Weight; Case-Control Studies; Cesarean Section; Delivery, Obstetric; Female; Fetal Blood; Gestational Age; Homocysteine; Humans; Hydrogen-Ion Concentration; Maternal Age; Obesity; Pregnancy; Pregnancy Complications; Young Adult | 2016 |
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model.
Topics: Animals; Betaine; Caloric Restriction; Carbon; Choline; DNA Methylation; Female; Gene Expression; Homocysteine; Hydrolases; Liver; Male; Methylamines; Models, Biological; Pregnancy; Pregnancy, Animal; Rats, Wistar; S-Adenosylmethionine | 2018 |
Maternal one carbon metabolism and arsenic methylation in a pregnancy cohort in Mexico.
Topics: Adult; Arsenic; Biomarkers; Cohort Studies; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Methylation; Mexico; Pregnancy; Pregnant Women; Regression Analysis; Vitamin B 12; Young Adult | 2018 |
Association of Bone Turnover Levels with MTHFR Gene Polymorphisms among Pregnant Women in Wuhan, China.
Topics: Adult; Bone Resorption; China; Female; Heterozygote; Homocysteine; Humans; Lead; Methylenetetrahydrofolate Reductase (NADPH2); Osteocalcin; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications | 2018 |
Changes of serum homocysteine levels during pregnancy and the establishment of reference intervals in pregnant Chinese women.
Topics: Adult; Asian People; Blood Chemical Analysis; Female; Homocysteine; Humans; Pregnancy; Pregnancy Trimesters; Reference Values | 2019 |
Prenatal particulate air pollution exposure and cord blood homocysteine in newborns: Results from the ENVIRONAGE birth cohort.
Topics: Adult; Air Pollutants; Air Pollution; Female; Fetal Blood; Homocysteine; Humans; Infant, Newborn; Maternal Exposure; Particulate Matter; Pregnancy | 2019 |
Association of pre-eclampsia risk with maternal levels of folate, homocysteine and vitamin B12 in Colombia: A case-control study.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Colombia; Female; Folic Acid; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Vitamin B 12; Young Adult | 2018 |
Hydrogen Sulfide Ameliorates Developmental Impairments of Rat Offspring with Prenatal Hyperhomocysteinemia.
Topics: Animals; Antioxidants; Brain; Female; Glutathione Peroxidase; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Lipid Peroxidation; Locomotion; Malondialdehyde; Pregnancy; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Sulfides; Superoxide Dismutase | 2018 |
Moderately elevated preconception fasting plasma total homocysteine is a risk factor for psychological problems in childhood.
Topics: Adult; Child; Child Behavior; Child Development; Fasting; Female; Homocysteine; Humans; Longitudinal Studies; Maternal Nutritional Physiological Phenomena; Mothers; Pregnancy; Psychology, Child; Risk Factors | 2019 |
Higher maternal plasma folate, vitamin B
Topics: Adolescent; Adult; Biomarkers; Birth Weight; Blood Pressure; Case-Control Studies; Female; Fetal Blood; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Newborn; Infant, Premature; Nutritional Status; Pre-Eclampsia; Pregnancy; Premature Birth; Up-Regulation; Vitamin B 12; Young Adult | 2019 |
The Revised D-A-CH-Reference Values for the Intake of Vitamin B
Topics: Adolescent; Adult; Biological Availability; Child; Child, Preschool; Female; Homocysteine; Humans; Infant; Male; Pregnancy; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2019 |
The role of maternal homocysteine concentration in placenta-mediated complications: findings from the Ottawa and Kingston birth cohort.
Topics: Abortion, Spontaneous; Abruptio Placentae; Adult; Canada; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Maternal Serum Screening Tests; Odds Ratio; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Second; Risk Factors | 2019 |
Preconception folate status and reproductive outcomes among a prospective cohort of folate-replete women.
Topics: Abortion, Spontaneous; Adolescent; Adult; Anovulation; Female; Folic Acid; Homocysteine; Humans; Preconception Care; Pregnancy; Prospective Studies; Young Adult | 2019 |
Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid.
Topics: Animals; Behavior, Animal; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Growth and Development; Homocysteine; Methylation; MicroRNAs; Nervous System; Pregnancy; Rats, Wistar; Vitamin B 12 | 2019 |
Betaine ameliorates prenatal valproic-acid-induced autism-like behavioral abnormalities in mice by promoting homocysteine metabolism.
Topics: Animals; Antimanic Agents; Autism Spectrum Disorder; Behavior, Animal; Betaine; Disease Models, Animal; Female; Homocysteine; Mice; Mice, Inbred ICR; Pregnancy; Prenatal Exposure Delayed Effects; Protective Agents; Social Behavior; Valproic Acid | 2019 |
Maternal betaine status, but not that of choline or methionine, is inversely associated with infant birth weight.
Topics: Adult; Betaine; Birth Weight; Choline; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Pregnancy Trimesters; Sarcosine | 2019 |
Maternal vitamin D deficiency increases the thromboxane/prostacyclin ratio through alterations in the one-carbon cycle in Wistar rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcium; Cyclooxygenase 2; Cystathionine beta-Synthase; Disease Models, Animal; Female; Folic Acid; Gene Expression Regulation; Group II Phospholipases A2; Homocysteine; Humans; Malondialdehyde; Parathyroid Hormone; Phosphates; Placenta; Pregnancy; Rats; Rats, Wistar; Signal Transduction; Thromboxane B2; Vitamin B 12; Vitamin D Deficiency | 2019 |
Associations between folate and choline intake, homocysteine metabolism, and genetic polymorphism of MTHFR, BHMT and PEMT in healthy pregnant Polish women.
Topics: Adolescent; Adult; Betaine-Homocysteine S-Methyltransferase; Choline; Female; Folic Acid; Genotype; Glutathione; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Genetic; Pregnancy; Pregnancy Trimester, Third; Young Adult | 2020 |
Investigating vitamin B12 deficiency.
Topics: Adult; Aged; Biomarkers; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Infant; Malabsorption Syndromes; Male; Malnutrition; Methylmalonic Acid; Physical Examination; Practice Guidelines as Topic; Pregnancy; Referral and Consultation; Risk Factors; United Kingdom; Vitamin B 12; Vitamin B 12 Deficiency; Vulnerable Populations | 2019 |
Association between Homocysteine and Arterial Stiffness in Women with a History of Preeclampsia.
Topics: Adult; Biomarkers; Blood Pressure; Case-Control Studies; China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Peripheral Arterial Disease; Pre-Eclampsia; Pregnancy; Prognosis; Risk Assessment; Risk Factors; Time Factors; Vascular Stiffness | 2019 |
Investigation of the association between C677T polymorphism of the MTHFR gene and plasma homocysteine level in recurrent fetal miscarriage.
Topics: Abortion, Habitual; Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy | 2019 |
Interactions between genetic variants involved in the folate metabolic pathway and serum lipid, homocysteine levels on the risk of recurrent spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Alleles; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy | 2019 |
Association of MTHFR C677T, MTHFR A1298C, and MTRR A66G Polymorphisms with Neural Tube Defects in Tunisian Parents.
Topics: Alleles; Fathers; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Homocystinuria; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Muscle Spasticity; Neural Tube Defects; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pregnancy; Psychotic Disorders; Tunisia | 2019 |
Maternal and cord blood homocysteine, vitamin B12, folate, and B-type natriuretic peptide levels at term for predicting congenital heart disease of the neonate: A case-control study.
Topics: Case-Control Studies; Female; Fetal Blood; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Natriuretic Peptide, Brain; Pregnancy; Vitamin B 12 | 2020 |
Evaluation of Plasma Homocysteine Levels in Patients of PCOS.
Topics: Case-Control Studies; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Insulin Resistance; Male; Polycystic Ovary Syndrome; Pregnancy | 2018 |
CORRELATION BETWEEN LEVELS OF HOMOCYSTEINE, ANTI-MÜLLERIAN HORMONE AND INSULIN RESISTANCE IN PCOS PATIENTS WITH RECURRENT MISCARRIAGE.
Topics: Abortion, Habitual; Adult; Anti-Mullerian Hormone; Female; Follicle Stimulating Hormone; Homocysteine; Humans; Insulin Resistance; Luteinizing Hormone; Polycystic Ovary Syndrome; Pregnancy; Prospective Studies; Testosterone | 2019 |
Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia.
Topics: Case-Control Studies; CpG Islands; DNA Methylation; Epigenesis, Genetic; Female; Folate Receptor 1; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Leukocytes; Neural Tube Defects; Placenta; Polymorphism, Single Nucleotide; Pregnancy; Proton-Coupled Folate Transporter; Replication Protein C; RNA, Messenger; Transcription, Genetic | 2013 |
Effect of maternal and postweaning folic acid supplementation on global and gene-specific DNA methylation in the liver of the rat offspring.
Topics: Animals; Animals, Newborn; Diet; Dietary Supplements; DNA Methylation; Female; Folic Acid; Homocysteine; Liver; PPAR gamma; Pregnancy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Weaning | 2013 |
Pre-pregnancy obesity and maternal nutritional biomarker status during pregnancy: a factor analysis.
Topics: Adult; alpha-Tocopherol; Ascorbic Acid; Biomarkers; Body Mass Index; Carotenoids; Cross-Sectional Studies; Factor Analysis, Statistical; Fatty Acids, Essential; Female; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Micronutrients; Nutritional Status; Obesity; Pregnancy; Prospective Studies; Receptors, Transferrin; Vitamin A; Vitamin D; Women's Health; Young Adult | 2013 |
Maternal first-trimester dietary intake and childhood blood pressure: the Generation R Study.
Topics: Blood Pressure; Child; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hypertension; Male; Maternal Nutritional Physiological Phenomena; Micronutrients; Netherlands; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Vitamin B 12 | 2013 |
Hyperhomocysteinemia is detrimental to pregnancy in mice and is associated with preterm birth.
Topics: Animals; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystathionine beta-Synthase; Dinoprostone; Female; Homocysteine; Humans; Hyperhomocysteinemia; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Mice; Mice, Inbred C57BL; Muscle Contraction; Myometrium; Placenta; Pregnancy; Pregnancy Complications; Premature Birth; Receptors, Nicotinic; Receptors, Oxytocin; Trophoblasts; Up-Regulation; Uterus | 2013 |
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.
Topics: Adult; Betaine; Choline; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Nutritional Status; Pregnancy; Sarcosine; Spain; Vitamin B 12 | 2013 |
Erythrocyte folate content and serum folic acid and homocysteine levels in preeclamptic primigravidae teenagers living at high altitude.
Topics: Adolescent; Adult; Altitude; Case-Control Studies; Erythrocytes; Female; Folic Acid; Gravidity; Hematocrit; Homocysteine; Humans; Pilot Projects; Pre-Eclampsia; Pregnancy; Young Adult | 2013 |
Homocysteine levels and its association with intraventricular hemorrhage in preterm infants born to preeclamptic mothers.
Topics: Case-Control Studies; Cerebral Hemorrhage; Female; Gestational Age; Homocysteine; Humans; Infant Mortality; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Pre-Eclampsia; Pregnancy; Turkey | 2013 |
MTHFR C677T polymorphism, folate, vitamin B12 and homocysteine in recurrent pregnancy losses: a case control study among North Indian women.
Topics: Abortion, Habitual; Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; India; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
The heart-placenta axis in the first month of pregnancy: induction and prevention of cardiovascular birth defects.
Topics: Animals; Birds; Cell Differentiation; Dietary Supplements; Disease Models, Animal; Ethanol; Female; Folic Acid; Folic Acid Deficiency; Gestational Age; Heart; Heart Defects, Congenital; Homocysteine; Humans; Lithium Compounds; Maternal Exposure; Mice; Myocytes, Cardiac; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Signal Transduction; Wnt Proteins | 2013 |
Maternal first-trimester diet and childhood bone mass: the Generation R Study.
Topics: Absorptiometry, Photon; Adult; Bone Density; Calcium, Dietary; Child; Diet; Female; Folic Acid; Homocysteine; Humans; Life Style; Magnesium; Male; Maternal Nutritional Physiological Phenomena; Phosphorus, Dietary; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12 | 2013 |
A comparison of maternal serum levels of endothelial nitric oxide synthase, asymmetric dimethylarginine, and homocysteine in normal and preeclamptic pregnancies.
Topics: Adult; Arginine; Case-Control Studies; Female; Homocysteine; Humans; Nitric Oxide Synthase Type III; Pre-Eclampsia; Pregnancy | 2013 |
Are vitamin B(12) levels really increased in women delivering preterm?
Topics: Female; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Pregnancy; Premature Birth; Vitamin B 12; Vitamin B Complex | 2013 |
Hypertension in pregnancy is associated with elevated homocysteine levels later in life.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Pregnancy-Induced; Linear Models; Logistic Models; Middle Aged; Pregnancy; Time Factors | 2013 |
A prospective study of maternal fatty acids, micronutrients and homocysteine and their association with birth outcome.
Topics: Adult; Birth Weight; Chromatography, Gas; Fatty Acids; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; India; Longitudinal Studies; Luminescent Measurements; Micronutrients; Mothers; Pregnancy; Prospective Studies; Vitamin B 12; Young Adult | 2015 |
Nutrition throughout life: folate.
Topics: Biological Availability; Cardiovascular Diseases; Drug Stability; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Neural Tube Defects; Nutrition Policy; Nutritional Physiological Phenomena; Nutritional Requirements; Nutritional Status; Pregnancy | 2012 |
Prenatal omega 3 fatty acid supplementation to a micronutrient imbalanced diet protects brain neurotrophins in both the cortex and hippocampus in the adult rat offspring.
Topics: Animal Nutritional Physiological Phenomena; Animals; Brain; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cognition; Diet; Dietary Supplements; Fatty Acids, Omega-3; Female; Folic Acid; Folic Acid Deficiency; Hippocampus; Homocysteine; Maze Learning; Micronutrients; Nerve Growth Factor; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Relationship between plasma total homocysteine level and dietary caffeine and vitamin B6 intakes in pregnant women.
Topics: Adult; Biomarkers; Caffeine; Cross-Sectional Studies; Diet; Female; Fetal Development; Homocysteine; Humans; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Reference Values; Risk Factors; Tea; Tokyo; Vitamin B 6 | 2014 |
Mendelian randomization analysis of the effect of maternal homocysteine during pregnancy, as represented by maternal MTHFR C677T genotype, on birth weight.
Topics: Adult; Birth Weight; Female; Genotype; Homocysteine; Humans; Infant, Newborn; Male; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Prenatal Exposure Delayed Effects; Republic of Korea | 2013 |
Influence of maternal vitamin B12 and folate on growth and insulin resistance in the offspring.
Topics: Adiposity; Adolescent; Adult; Animals; Body Weight; Carbon; Cardiovascular Diseases; Child; Chronic Disease; Diabetes Mellitus; Female; Folic Acid; Folic Acid Deficiency; Growth; Homocysteine; Humans; India; Infant; Infant, Newborn; Insulin Resistance; Maternal Nutritional Physiological Phenomena; Neural Tube Defects; Nutritional Status; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Genetic association of five plasminogen activator inhibitor-1 (PAI-1) polymorphisms and idiopathic recurrent pregnancy loss in Korean women.
Topics: Abortion, Habitual; Adult; Blood Coagulation; DNA Mutational Analysis; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Korea; Middle Aged; Mutation; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Pregnancy; Young Adult | 2013 |
Phospholipase D-mediated hypersensitivity at central synapses is associated with abnormal behaviours and pain sensitivity in rats exposed to prenatal stress.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Female; Homocysteine; Hypersensitivity; Male; Neurons; Nociception; Pain; Phospholipase D; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Spinal Cord; Stress, Psychological; Synapses | 2013 |
Low birthweight (LBW) and neonatal hyperbilirubinemia (NNH) in an Indian cohort: association of homocysteine, its metabolic pathway genes and micronutrients as risk factors.
Topics: Cohort Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperbilirubinemia, Neonatal; Incidence; India; Infant, Low Birth Weight; Infant, Newborn; Male; Micronutrients; Pregnancy; Risk Factors; Vitamin B 12 | 2013 |
Levels of key enzymes of methionine-homocysteine metabolism in preeclampsia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Female; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Effects of taurine supplementation on hepatic markers of inflammation and lipid metabolism in mothers and offspring in the setting of maternal obesity.
Topics: Animals; Animals, Newborn; Biomarkers; Body Weight; Dietary Supplements; Disease Models, Animal; Female; Gene Expression; Glucose; Glutamic Acid; Homocysteine; Inflammation; Lipid Metabolism; Liver; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Taurine | 2013 |
Association between maternal folate concentrations during pregnancy and insulin resistance in Indian children.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Pregnancy; Vitamin B 12; Young Adult | 2014 |
Gestational methyl donor deficiency alters key proteins involved in neurosteroidogenesis in the olfactory bulbs of newborn female rats and is associated with impaired olfactory performance.
Topics: Animals; Animals, Newborn; Apoptosis; Aromatase; Diet; DNA Methylation; Estrogen Receptor alpha; Female; Gene Expression; Homocysteine; Lactation; Male; Methylation; Neurogenesis; Neurotransmitter Agents; Olfaction Disorders; Olfactory Bulb; Phosphoproteins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Weaning | 2014 |
Homocysteine and C-reactive protein as useful surrogate markers for evaluating CKD risk in adults.
Topics: Adult; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Pregnancy; Renal Insufficiency, Chronic; Retrospective Studies; Risk Factors; Sex Characteristics; Taiwan | 2013 |
Development of an animal model for gestational hypermethioninemia in rat and its effect on brain Na⁺,K⁺-ATPase/Mg²⁺-ATPase activity and oxidative status of the offspring.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Animals, Newborn; Brain; Brain Chemistry; Ca(2+) Mg(2+)-ATPase; Catalase; Disease Models, Animal; Female; Glycine N-Methyltransferase; Homocysteine; Maternal-Fetal Exchange; Methionine; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2014 |
Maternal methyl donors supplementation during lactation prevents the hyperhomocysteinemia induced by a high-fat-sucrose intake by dams.
Topics: Animals; Body Weight; Diet, High-Fat; Dietary Sucrose; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Female; Homocysteine; Hyperhomocysteinemia; Lactation; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylmethionine | 2013 |
Association of homocysteine with global DNA methylation in vegetarian Indian pregnant women and neonatal birth anthropometrics.
Topics: Adult; Birth Weight; Body Weights and Measures; Diet, Vegetarian; DNA Methylation; Female; Homocysteine; Humans; India; Infant, Newborn; Maternal Nutritional Physiological Phenomena; Nutrition Surveys; Nutritional Status; Parturition; Pregnancy; Young Adult | 2014 |
Imbalance of folic acid and vitamin B12 is associated with birth outcome: an Indian pregnant women study.
Topics: Anthropometry; Birth Weight; Body Size; Dietary Supplements; Female; Folic Acid; Head; Hematinics; Homocysteine; Humans; India; Nutritional Requirements; Pregnancy; Pregnancy Complications; Thorax; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Young Adult | 2014 |
The effect of multiple single nucleotide polymorphisms in the folic acid pathway genes on homocysteine metabolism.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Metabolic Networks and Pathways; Polymorphism, Single Nucleotide; Pregnancy | 2014 |
Conotruncal heart defects and common variants in maternal and fetal genes in folate, homocysteine, and transsulfuration pathways.
Topics: Adult; Bayes Theorem; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Glutamate-Cysteine Ligase; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Polymorphism, Single Nucleotide; Pregnancy; Prospective Studies; Risk Factors; Thymidylate Synthase | 2014 |
Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in nulliparous women complicated with preeclampsia.
Topics: Case-Control Studies; Chi-Square Distribution; DNA; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Young Adult | 2014 |
Effect of vitamin B deprivation during pregnancy and lactation on homocysteine metabolism and related metabolites in brain and plasma of mice offspring.
Topics: Animals; Brain; Female; Folic Acid; Homocysteine; Lactation; Male; Mice; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B Deficiency | 2014 |
Fetal sex specific differences in human placentation: a prospective cohort study.
Topics: Biomarkers; Cohort Studies; Female; Homocysteine; Humans; Linear Models; Male; Placenta; Placenta Growth Factor; Placentation; Plasminogen Activator Inhibitor 2; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Pregnancy Trimester, First; Prospective Studies; Receptor, Fibroblast Growth Factor, Type 1; Sex Factors; Vascular Endothelial Growth Factor Receptor-1 | 2014 |
Association of neural tube defects in children of mothers with MTHFR 677TT genotype and abnormal carbohydrate metabolism risk: a case-control study.
Topics: Adult; Alleles; Carbohydrate Metabolism; Case-Control Studies; Female; Genetic Association Studies; Genotype; Homocysteine; Humans; Incidence; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Neural Tube Defects; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Spinal Dysraphism; Young Adult | 2014 |
Folic acid supplementation and IVF pregnancy outcome in women with unexplained infertility.
Topics: Adult; Dietary Supplements; Female; Fertilization in Vitro; Folic Acid; Homocysteine; Humans; Infertility, Female; Pregnancy; Pregnancy Outcome | 2014 |
What is new in obstetric antecedents of chronic disease? Best articles from the past year.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Diabetes, Gestational; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Pregnancy-Induced; Kidney Diseases; Obesity; Pregnancy; Premature Birth | 2014 |
Maternal plasma homocysteine levels in intrauterine growth retardation.
Topics: Adult; Birth Weight; Blood Flow Velocity; Case-Control Studies; Female; Fetal Growth Retardation; Gestational Age; Homocysteine; Humans; Infant, Newborn; Middle Cerebral Artery; Pregnancy; Ultrasonography; Umbilical Arteries; Young Adult | 2015 |
Quantification of folate metabolites in serum using ultraperformance liquid chromatography tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Limit of Detection; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Tetrahydrofolates | 2014 |
Revisiting the role of first trimester homocysteine as an index of maternal and fetal outcome.
Topics: Abortion, Spontaneous; Adult; Amniotic Fluid; Cohort Studies; Diabetes, Gestational; Female; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Infant, Low Birth Weight; Meconium; Oligohydramnios; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Young Adult | 2014 |
GABA derivatives citrocard and salifen reduce the intensity of experimental gestosis.
Topics: Animals; Blood Pressure; Brain; Female; GABA Agonists; gamma-Aminobutyric Acid; Glycosaminoglycans; Homocysteine; Muscle, Skeletal; Omentum; Pre-Eclampsia; Pregnancy; Rats; Sodium Chloride | 2014 |
Homocysteine levels and bad obstetric outcome among female operating room personnel occupationally exposed to nitrous oxide.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Nitrous Oxide; Occupational Exposure; Operating Room Technicians; Pregnancy; Pregnancy Outcome; Reproductive History; Vitamin B 12 | 2014 |
Metabolic syndrome in Spanish adolescents and its association with birth weight, breastfeeding duration, maternal smoking, and maternal obesity: a cross-sectional study.
Topics: Adolescent; Birth Weight; Blood Pressure; Body Mass Index; Breast Feeding; Ceruloplasmin; Child; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Female; Homocysteine; Humans; Logistic Models; Male; Metabolic Syndrome; Mothers; Obesity; Overweight; Pregnancy; Prevalence; Risk Factors; Smoking; Spain; Triglycerides; White People | 2015 |
Maternal homocysteine in pregnancy and offspring birthweight: epidemiological associations and Mendelian randomization analysis.
Topics: Adult; Biomarkers; Birth Weight; Cohort Studies; Female; Fetal Development; Folic Acid; Genotype; Gestational Age; Homocysteine; Humans; India; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12 | 2014 |
Increased systolic blood pressure in rat offspring following a maternal low-protein diet is normalized by maternal dietary choline supplementation.
Topics: Animals; Blood Pressure; Body Weight; Choline; Diet, Protein-Restricted; Dietary Supplements; Female; Homocysteine; Male; Maternal Nutritional Physiological Phenomena; Phosphatidylcholines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 2012 |
Commentary: One-carbon metabolism has major implications for fetal growth and development beyond neural tube defects.
Topics: Birth Weight; Female; Homocysteine; Humans; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Prenatal Exposure Delayed Effects | 2014 |
Maternal vitamin B12 deficiency detected in expanded newborn screening.
Topics: Carnitine; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Genetic and non-genetic factors that increase the risk of non-syndromic cleft lip and/or palate development.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alcohol Drinking; Brain; Case-Control Studies; Child; Cleft Lip; Cleft Palate; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene-Environment Interaction; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Prenatal Exposure Delayed Effects; Replication Protein C; Young Adult | 2015 |
Localization of folate metabolic enzymes, methionine synthase and 5,10-methylenetetrahydrofolate reductase in human placenta.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Blotting, Western; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Immunohistochemistry; Methylenetetrahydrofolate Reductase (NADPH2); Placenta; Pregnancy; RNA, Messenger; Trophoblasts | 2014 |
Reliable and powerful laboratory markers of cobalamin deficiency in the newborn: plasma and urinary methylmalonic acid.
Topics: Adult; Biomarkers; Cohort Studies; Female; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
Determinants of maternal pregnancy one-carbon metabolism and newborn human DNA methylation profiles.
Topics: Adult; Carbon; Cohort Studies; DNA; DNA Methylation; Epigenesis, Genetic; Female; Fetal Development; Folic Acid; Genotype; Homocysteine; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy | 2014 |
Chronic maternal vitamin B12 restriction induced changes in body composition & glucose metabolism in the Wistar rat offspring are partly correctable by rehabilitation.
Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Body Composition; Body Weight; Catalase; Female; Glucose; Homocysteine; Insulin; Liver; Male; Malnutrition; Maternal Nutritional Physiological Phenomena; Models, Animal; Oxidative Stress; Phosphoenolpyruvate Carboxykinase (ATP); Pregnancy; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin B 12 | 2014 |
Adherence to Mediterranean diet during pregnancy and serum lipid, lipoprotein and homocysteine concentrations at birth.
Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Diet, Mediterranean; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Female; Fetal Blood; Follow-Up Studies; Homocysteine; Humans; Lipoproteins; Maternal Nutritional Physiological Phenomena; Patient Compliance; Pregnancy; Surveys and Questionnaires; White People; Young Adult | 2015 |
Melatonin prevents oxidative damage induced by maternal ethanol administration and reduces homocysteine in the cerebellum of rat pups.
Topics: Animals; bcl-2-Associated X Protein; Catalase; Central Nervous System Depressants; Cerebellum; Ethanol; Female; Glutathione Peroxidase; Homocysteine; Lipid Peroxidation; Locomotion; Melatonin; Neuroprotective Agents; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats, Wistar; RNA, Messenger; Superoxide Dismutase | 2015 |
Formate metabolism in fetal and neonatal sheep.
Topics: Amniotic Fluid; Animals; Animals, Newborn; Female; Fetus; Folic Acid; Formates; Homocysteine; Postpartum Period; Pregnancy; Pregnancy, Animal; Sheep; Vitamin B 12 | 2015 |
Obstructive heart defects associated with candidate genes, maternal obesity, and folic acid supplementation.
Topics: Adult; Betaine-Homocysteine S-Methyltransferase; Cardiomyopathy, Hypertrophic; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Female; Folic Acid; Gene Expression; Gene-Environment Interaction; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Models, Genetic; Obesity; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors | 2015 |
Low maternal vitamin B12 status is associated with lower cord blood HDL cholesterol in white Caucasians living in the UK.
Topics: Adult; Blood Glucose; Body Mass Index; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Diet, Vegetarian; Female; Fetal Blood; Folic Acid; Gestational Age; Homocysteine; Humans; Insulin; Insulin Resistance; Maternal Nutritional Physiological Phenomena; Nutritional Status; Pregnancy; Risk Factors; Triglycerides; United Kingdom; Vitamin B 12; White People | 2015 |
Folate, vitamin B12 and Homocysteine status in the post-folic acid fortification era in different subgroups of the Brazilian population attended to at a public health care center.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Brazil; Carboxypeptidases; Child; Child, Preschool; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Lactation; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; Prevalence; Reduced Folate Carrier Protein; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2015 |
MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring.
Topics: Animals; Apoptosis; Body Weight; Choline Deficiency; Choline O-Acetyltransferase; Disease Models, Animal; Female; Folic Acid Deficiency; Hippocampus; Homocysteine; Homocystinuria; Male; Maternal Nutritional Physiological Phenomena; Maze Learning; Memory Disorders; Memory, Short-Term; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Transgenic; Muscle Spasticity; Neurogenesis; Organ Size; Pregnancy; Pregnancy Complications; Psychotic Disorders; Recognition, Psychology | 2015 |
Vitamin B12 and omega-3 fatty acids together regulate lipid metabolism in Wistar rats.
Topics: Adiponectin; Animals; Blood Pressure; Cholesterol; Diet; Dietary Supplements; Fatty Acids, Omega-3; Female; Homocysteine; Lipid Metabolism; Liver; Male; Pregnancy; Prenatal Nutritional Physiological Phenomena; Rats, Wistar; RNA, Messenger; Triglycerides; Vitamin B 12 | 2015 |
Role of folate-homocysteine pathway gene polymorphisms and nutritional cofactors in Down syndrome: A triad study.
Topics: Adult; Alleles; Diet; Down Syndrome; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors | 2015 |
Homocysteinemia After Hypertensive Pregnancy Disorders at Term.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Pregnancy-Induced; Linear Models; Logistic Models; Longitudinal Studies; Middle Aged; Pregnancy; Prospective Studies; Risk Factors; Time Factors | 2015 |
The evaluation of homocysteine level in patients with preeclampsia.
Topics: Adult; Biomarkers; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Prenatal Care; Risk Factors; Severity of Illness Index | 2015 |
Prenatal diagnosis using genetic sequencing and identification of a novel mutation in MMACHC.
Topics: Amino Acid Metabolism, Inborn Errors; Base Sequence; Carrier Proteins; China; Computational Biology; Female; Fluorescence Polarization Immunoassay; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Male; Molecular Sequence Data; Mutation, Missense; Oxidoreductases; Pedigree; Polymerase Chain Reaction; Pregnancy; Prenatal Diagnosis; Sequence Analysis, DNA; Urinalysis; Vitamin B 12 Deficiency | 2015 |
Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre-eclampsia: a longitudinal study.
Topics: Adult; Arginine; Biomarkers; Body Mass Index; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Longitudinal Studies; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Risk Factors; United Kingdom; Vitamin B Complex; Vitamin B Deficiency | 2015 |
Correlation between MTHFR gene methylation and pre-eclampsia, and its clinical significance.
Topics: Adult; Case-Control Studies; DNA Methylation; Electrophoresis, Agar Gel; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Pre-Eclampsia; Pregnancy; Vitamin B 12 | 2015 |
Folate Deficiency Could Restrain Decidual Angiogenesis in Pregnant Mice.
Topics: Animals; Decidua; Down-Regulation; Estradiol; Female; Folic Acid Deficiency; Follicle Stimulating Hormone; Homocysteine; Luteinizing Hormone; Male; Mice; Neovascularization, Physiologic; Placenta Growth Factor; Pregnancy; Pregnancy Proteins; Progesterone; Prolactin; Reproducibility of Results; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
High concentrations of folate and unmetabolized folic acid in a cohort of pregnant Canadian women and umbilical cord blood.
Topics: Adult; Canada; Dietary Supplements; Energy Intake; Female; Fetal Blood; Folic Acid; Gene Frequency; Genetic Variation; Genotype; Homocysteine; Humans; Logistic Models; Maternal Nutritional Physiological Phenomena; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutrition Assessment; Polymorphism, Single Nucleotide; Pregnancy; Prospective Studies; Surveys and Questionnaires; Tetrahydrofolate Dehydrogenase; Young Adult | 2015 |
[Interactions between markers of endothelial damage (homocysteine and asymmetric dimethylarginine) and antioxidants and B-vitamins in preeclamptic women].
Topics: Adolescent; Adult; Antioxidants; Arginine; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Prospective Studies; Regression Analysis; Vitamin B Complex; Vitamin B Deficiency; Young Adult | 2015 |
Proteomic Analysis of One-carbon Metabolism-related Marker in Liver of Rat Offspring.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Biomarkers; Blood Glucose; Caloric Restriction; Carbon; Female; Gene Expression Profiling; Gene Expression Regulation; Homocysteine; Lactation; Liver; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondrial Proton-Translocating ATPases; Pregnancy; Prenatal Exposure Delayed Effects; Proteomics; Rats; Rats, Sprague-Dawley | 2015 |
Association of maternal homocysteine and vitamins status with the risk of neural tube defects in Tunisia: A case-control study.
Topics: Adult; Case-Control Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Radioimmunoassay; Risk Factors; Tunisia; Vitamins | 2015 |
Evaluation of fatty acids in pregnancy: plasma or erythrocyte membrane?
Topics: Birth Weight; Fatty Acids; Female; Folic Acid; Homocysteine; Humans; Mothers; Pregnancy; Vitamin B 12 | 2015 |
Fetal Val108/158Met catechol-O-methyltransferase (COMT) polymorphism and placental COMT activity are associated with the development of preeclampsia.
Topics: 2-Methoxyestradiol; Adult; Biomarkers; Blood Pressure; Case-Control Studies; Catechol O-Methyltransferase; Chi-Square Distribution; Estradiol; Female; Fetal Blood; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Hospitals, University; Humans; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Odds Ratio; Phenotype; Placenta; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Prospective Studies; Risk Assessment; Risk Factors; Spain | 2016 |
The levels of vitamın B12, folate and homocysteine in mothers and their babies with neural tube defects.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Middle Aged; Neural Tube Defects; Pregnancy; Prevalence; Risk Factors; Turkey; Vitamin B 12; Young Adult | 2016 |
Increased homocysteine levels exist in women with preeclampsia from early pregnancy.
Topics: Adult; Diet; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Prospective Studies; Vitamin B 12 | 2016 |
Homocysteine Levels Are not Related to Telomere Length in Cord Blood Leukocytes of Newborns.
Topics: Adolescent; Adult; DNA; Female; Fetal Blood; Florida; Gestational Age; Homocysteine; Humans; Infant, Newborn; Leukocytes; Linear Models; Pregnancy; Prospective Studies; Statistics as Topic; Telomere; Young Adult | 2016 |
Placental NRP1 and VEGF expression in pre-eclamptic women and in a homocysteine-treated mouse model of pre-eclampsia.
Topics: Adult; Animals; Disease Models, Animal; Female; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Neuropilin-1; Placenta; Pre-Eclampsia; Pregnancy; Vascular Endothelial Growth Factor A | 2016 |
Homocysteine in embryo culture media as a predictor of pregnancy outcome in assisted reproductive technology.
Topics: Embryo Culture Techniques; Embryo, Mammalian; Female; Homocysteine; Humans; Pregnancy; Pregnancy Outcome; Reproductive Techniques, Assisted | 2016 |
Maternal B vitamins: effects on offspring weight and DNA methylation at genomically imprinted domains.
Topics: Adult; Birth Weight; Cell Cycle Proteins; Child, Preschool; DNA Methylation; Female; Homocysteine; Humans; Infant, Newborn; Male; Pregnancy; RNA, Long Noncoding; Sarcoglycans; Transcription Factors; Tumor Suppressor Proteins; Vitamin B 12; Vitamin B 6; Weight Gain; Young Adult | 2016 |
Moderately elevated maternal homocysteine at preconception is inversely associated with cognitive performance in children 4 months and 6 years after birth.
Topics: Adult; Body Height; Body Mass Index; Body Weight; Brain; Child; Child Development; Cognition; Cross-Sectional Studies; Dietary Supplements; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Logistic Models; Male; Maternal Nutritional Physiological Phenomena; Micronutrients; Pregnancy; Prenatal Care; Prenatal Exposure Delayed Effects; Prospective Studies; Socioeconomic Factors; Spain; Vitamin B 12 | 2017 |
Homocysteine, endothelin-1 and nitric oxide in patients with hypertensive disorders complicating pregnancy.
Topics: Adult; Biomarkers; Blood Pressure; Case-Control Studies; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Nitric Oxide; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Severity of Illness Index; Young Adult | 2015 |
[Correlation between offspring congenital heart disease and MTHFR 677C/T polymorphism and general status of pregnant women].
Topics: Case-Control Studies; Female; Folic Acid; Gene Frequency; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Prevalence | 2015 |
Prognostic Value of Cardiovascular Disease Risk Factors Measured in the First-Trimester on the Severity of Preeclampsia.
Topics: Adult; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Female; Fetal Growth Retardation; Homocysteine; Humans; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Risk Factors; ROC Curve; Severity of Illness Index | 2016 |
Investigation into homocysteine [corrected], vitamin E and malondialdehyde as indicators of successful artificial insemination in synchronized buffalo cows (Bubalus bubalis).
Topics: Animals; Buffaloes; Estrus Synchronization; Female; Homocysteine; Insemination, Artificial; Malondialdehyde; Pregnancy; Vitamin E | 2016 |
Simultaneous detection of five one-carbon metabolites in plasma using stable isotope dilution liquid chromatography tandem mass spectrometry.
Topics: Female; Homocysteine; Humans; Isotope Labeling; Limit of Detection; Linear Models; Methionine; Pregnancy; Reproducibility of Results; Tandem Mass Spectrometry; Vitamin B 12 Deficiency | 2016 |
Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects.
Topics: Animals; Autoantibodies; Blood Proteins; Diet; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Folic Acid Deficiency; Gestational Age; Homocysteine; Humans; Mice; Mice, Inbred C57BL; Neural Tube Defects; Pregnancy; Protein Processing, Post-Translational | 2016 |
The association of single nucleotide polymorphisms of the maternal cystathionine-β-synthase gene with early-onset preeclampsia.
Topics: Adult; Biomarkers; Blood Pressure; Case-Control Studies; Cystathionine; Cystathionine beta-Synthase; Cysteine; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Gestational Age; Homocysteine; Humans; Phenotype; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Protective Factors; Risk Factors | 2016 |
Embryonic exposures of lithium and homocysteine and folate protection affect lipid metabolism during mouse cardiogenesis and placentation.
Topics: Acyl-CoA Dehydrogenase; Animals; Cadherins; Cardiotonic Agents; Computational Biology; Embryo, Mammalian; Female; Folic Acid; Heart; Homocysteine; Lipid Metabolism; Lithium Chloride; Male; Mice, Inbred C57BL; Myocardium; Placenta; Placentation; Pregnancy; Transcriptome | 2016 |
Does fish oil or folic acid prevent vascular changes in female progeny caused by maternal exposure to fluoxetine?
Topics: Animals; Antidepressive Agents, Second-Generation; Blood Vessels; Female; Fish Oils; Fluoxetine; Folic Acid; Homocysteine; Lactation; Male; Maternal Exposure; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Phenylephrine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Vasoconstrictor Agents | 2016 |
Nutritional Epidemiology of Antenatal Smoking Cessation Among Japanese Women.
Topics: Adult; Biomarkers; Body Mass Index; Body Weight; Diet; Energy Intake; Female; Hemoglobins; Homocysteine; Humans; Japan; Maternal Nutritional Physiological Phenomena; Nutritional Status; Pregnancy; Smoking Cessation | 2016 |
Low Serum Vitamin B-12 Concentrations Are Prevalent in a Cohort of Pregnant Canadian Women.
Topics: Adult; Canada; Diet; Dietary Supplements; DNA Methylation; Female; Fetal Blood; Fetus; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2016 |
Maternal exposure to ambient PM
Topics: Animals; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; GATA4 Transcription Factor; Heart; Homeobox Protein Nkx-2.5; Homocysteine; Interleukin-1beta; Male; Maternal Exposure; Myocardium; Oxidative Stress; Particulate Matter; Pregnancy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2017 |
Maternal and Neonatal Markers of the Homocysteine Pathway and Fetal Growth: The Generation R Study.
Topics: Adult; Biomarkers; Birth Weight; Female; Fetal Blood; Fetal Development; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Netherlands; Pregnancy; Pregnancy Proteins; Prenatal Exposure Delayed Effects; Prospective Studies; Vascular Endothelial Growth Factor Receptor-1; Vitamin B 12 | 2016 |
Maternal gut and fetal brain connection: Increased anxiety and reduced social interactions in Wistar rat offspring following peri-conceptional antibiotic exposure.
Topics: Acoustic Stimulation; Animals; Animals, Newborn; Anti-Infective Agents; Anxiety; Eating; Exploratory Behavior; Female; Homocysteine; Interpersonal Relations; Male; Maze Learning; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Rats; Rats, Wistar; Sulfathiazoles; Tryptophan | 2016 |
[Interaction between passive smoking and folic acid supplement during pregnancy on autism spectrum disorder behaviors in children aged 3 years].
Topics: Autism Spectrum Disorder; Child, Preschool; Dietary Supplements; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Infant, Low Birth Weight; Infant, Newborn; Parents; Pregnancy; Pregnancy Complications; Premature Birth; Smoking; Surveys and Questionnaires; Tobacco Smoke Pollution | 2016 |
Evaluation of maternal serum folate, vitamin B12, and homocysteine levels andfactor V Leiden, factor II g.20210G>A, and MTHFR variations in prenatallydiagnosed neural tube defects.
Topics: Female; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Pregnancy; Prothrombin; Vitamin B 12 | 2016 |
Molecular and cellular effects of vitamin B12 forms on human trophoblast cells in presence of excessive folate.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Chorionic Gonadotropin, beta Subunit, Human; Cobamides; Cytoprotection; Dietary Supplements; Dose-Response Relationship, Drug; ErbB Receptors; Female; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Malondialdehyde; Pregnancy; Protective Agents; Trophoblasts; Tumor Necrosis Factor-alpha; Vitamin B 12 | 2016 |
Evaluation of Homocysteine, Vitamin B12 and Folic Acid Levels During all the Trimesters in Pregnant and Preeclamptic Womens.
Topics: Case-Control Studies; Female; Fetal Blood; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Pregnancy Trimesters; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Human Placental Arterial Distensibility, Birth Weight, and Body Size Are Positively Related to Fetal Homocysteine Concentration.
Topics: Arteries; Birth Weight; Blood Pressure; Body Size; Female; Fetal Blood; Fetal Development; Gestational Age; Homocysteine; Humans; Infant, Newborn; Male; Placenta; Pregnancy | 2017 |
A Prospective Study on Serum Methylmalonic Acid and Homocysteine in Pregnant Women.
Topics: Adult; Female; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Middle Aged; Pregnancy; Pregnancy Outcome; Prospective Studies; Republic of Korea; Young Adult | 2016 |
Blood folic acid, vitamin B12, and homocysteine levels in pregnant women with fetal growth restriction.
Topics: Adult; China; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Gestational Age; Homocysteine; Humans; Infant, Newborn; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
Disturbed nitric oxide and homocysteine production are involved in the increased risk of cardiovascular diseases in the F1 offspring of maternal obesity and malnutrition.
Topics: Animals; Animals, Newborn; Cardiovascular Diseases; Female; Homocysteine; Malnutrition; Nitric Oxide; Obesity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 2017 |
Periconceptional maternal one-carbon biomarkers are associated with embryonic development according to the Carnegie stages.
Topics: Adult; Biomarkers; Cohort Studies; Crown-Rump Length; Embryonic Development; Female; Folic Acid; Homocysteine; Humans; Pregnancy; Prospective Studies; Ultrasonography, Prenatal; Vitamin B 12; Young Adult | 2017 |
Patterns of Biomarkers in Cord Blood During Pregnancy and Preeclampsia.
Topics: Apoprotein(a); Biomarkers; Female; Fetal Blood; Folic Acid; Heme Oxygenase-1; Homocysteine; Humans; Infant, Newborn; Lipids; Pre-Eclampsia; Pregnancy; Thyroid Hormones; Thyrotropin; Vitamin B 12 | 2017 |
Maternal and Fetal Folate, Vitamin B
Topics: Albuminuria; Child; Child, Preschool; Cohort Studies; Female; Fetal Blood; Folic Acid; Follow-Up Studies; Glomerular Filtration Rate; Homocysteine; Humans; Infant; Infant, Newborn; Kidney Function Tests; Male; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Vitamin B 12 | 2017 |
That Which Is Bad Can Trigger Good in the Human Body-Homocysteine-Bound hnRNP-E1 as a Molecular Sensor of Physiologic Folate Deficiency.
Topics: Female; Folic Acid; Folic Acid Deficiency; Heterogeneous-Nuclear Ribonucleoproteins; Homocysteine; Human Body; Humans; Pregnancy; Up-Regulation | 2017 |
Has enhanced folate status during pregnancy altered natural selection and possibly Autism prevalence? A closer look at a possible link.
Topics: Autistic Disorder; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Genetic; Pregnancy; Selection, Genetic | 2008 |
Elevated plasma total homocysteine in preeclampsia.
Topics: Adult; Case-Control Studies; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy | 2008 |
Umbilical cord plasma homocysteine concentrations at delivery in pregnancies complicated by pre-eclampsia.
Topics: Adolescent; Adult; Female; Fetal Blood; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Term Birth | 2008 |
Maternal serum vitamin B12, folate and homocysteine and the risk of neural tube defects in the offspring in a high-risk area of China.
Topics: Adult; Case-Control Studies; China; Diet; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Luminescent Measurements; Maternal Nutritional Physiological Phenomena; Neural Tube Defects; Pregnancy; Pregnant Women; Risk Factors; Ultrasonography; Vitamin B 12; Young Adult | 2009 |
Neural tube defects and disturbed maternal folate- and homocysteine-mediated one-carbon metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Carbon; Case-Control Studies; Chi-Square Distribution; Chromatography; Female; Folic Acid; Homocysteine; Humans; Maternal Age; Models, Biological; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine | 2008 |
Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Cell Line, Tumor; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Pregnancy; Teratogens; Up-Regulation; Valproic Acid | 2008 |
Folate and clefts of the lip and palate--a U.K.-based case-control study: Part II: Biochemical and genetic analysis.
Topics: Case-Control Studies; Cleft Lip; Cleft Palate; Fathers; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Polymorphism, Single Nucleotide; Pregnancy; Regression Analysis; Surveys and Questionnaires; United Kingdom | 2008 |
Low serum vitamin B12 is associated with recurrent pregnancy loss in Syrian women.
Topics: Abortion, Habitual; Adult; Female; Homocysteine; Humans; Pregnancy; Syria; Vitamin B 12 | 2008 |
Endothelial dysfunction and reduced antioxidant protection in an animal model of the developmental origins of cardiovascular disease.
Topics: Animals; Antioxidants; Blood Pressure; Cardiovascular Diseases; Diet, Protein-Restricted; Endothelium, Vascular; Female; Gene Expression Regulation, Developmental; Guanylate Cyclase; Hemodynamics; Homocysteine; Male; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organ Size; Pregnancy; Protein Carbonylation; Rats; Rats, Wistar; RNA, Messenger; Sex Characteristics; Weight Gain | 2008 |
Dietary folate intake during pregnancy and birth weight in Japan.
Topics: Adult; Biomarkers; Birth Weight; Energy Intake; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant, Newborn; Japan; Longitudinal Studies; Male; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Nutritional Status; Pregnancy; Pregnancy Outcome; Prospective Studies; Vitamin B Complex | 2008 |
Serum homocysteine in pre-eclampsia and eclampsia.
Topics: Adult; Bangladesh; Case-Control Studies; Eclampsia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Pilot Projects; Pre-Eclampsia; Pregnancy; Risk Factors | 2008 |
[Thromboembolic events, abortions and a sick infant--unusual presentation of a vitamin deficiency].
Topics: Abortion, Habitual; Adult; Anemia, Pernicious; Autoimmune Diseases; Breast Feeding; Diagnosis, Differential; Failure to Thrive; Female; Folic Acid; Gastritis, Atrophic; Homocysteine; Humans; Infant; Intrinsic Factor; Methylmalonic Acid; Parietal Cells, Gastric; Pregnancy; Thromboembolism; Vitamin B 12 Deficiency | 2008 |
Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates.
Topics: Adult; Brazil; DNA; Embryonic Development; Ethnicity; Female; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pregnancy; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylhomocysteine; S-Adenosylmethionine; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2008 |
Maternal thrombophilia and the risk of recurrence of preeclampsia.
Topics: Antibodies, Anticardiolipin; Antithrombins; Birth Weight; Cohort Studies; Factor V; Female; Gestational Age; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Lupus Coagulation Inhibitor; Methylenetetrahydrofolate Reductase (NADPH2); Pre-Eclampsia; Pregnancy; Prospective Studies; Protein C; Protein S; Prothrombin; Regression Analysis; Thrombophilia | 2009 |
Low levels of maternal serum PAPP-A in early pregnancy and the risk of adverse outcomes.
Topics: Biomarkers; Case-Control Studies; Cohort Studies; Female; Homocysteine; Humans; Hypertension; Infant, Newborn; Infant, Small for Gestational Age; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, First; Pregnancy-Associated Plasma Protein-A | 2008 |
Invited commentary: Preventing neural tube defects and more via food fortification?
Topics: Confidence Intervals; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Maryland; Mothers; Neural Tube Defects; Pregnancy; Prenatal Care; United States; Vitamin B Complex | 2009 |
A study of changes in homocysteine levels during normal pregnancy and pre-eclampsia.
Topics: Adolescent; Adult; Case-Control Studies; Cross-Sectional Studies; Female; Fluorescence Polarization; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Welfare; Perinatal Care; Pre-Eclampsia; Pregnancy; Risk Factors; Young Adult | 2008 |
[Serum homocysteine levels in pregnant women with preeclampsia].
Topics: Adult; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Placental Circulation; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Severity of Illness Index; Ultrasonography, Doppler | 2005 |
Prevalence of MTHFR C677T polymorphism in north Indian mothers having babies with Trisomy 21 Down syndrome.
Topics: Adult; Diet; DNA; Down Syndrome; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; India; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Vitamins; Young Adult | 2008 |
Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss.
Topics: Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; DNA Damage; Embryo Loss; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Micronuclei, Chromosome-Defective; Parents; Polymorphism, Single Nucleotide; Pregnancy; Recurrence; Young Adult | 2009 |
[Homocysteine and its role in clinical practice (a lecture)].
Topics: Biomarkers; Clinical Chemistry Tests; Diabetes Mellitus; Female; Gastrointestinal Diseases; History, 20th Century; History, 21st Century; Homocysteine; Humans; Hyperhomocysteinemia; Hyperthyroidism; Kidney Diseases; Mental Disorders; Osteoporosis; Pregnancy; Pregnancy Complications, Cardiovascular | 2008 |
Prenatal hyperhomocysteinemia as a model of oxidative stress of the brain.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Cognition; Female; Fetus; Homocysteine; Hyperhomocysteinemia; Maze Learning; N-Methylaspartate; Oxidative Stress; Pregnancy; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2008 |
Plasma homocysteine concentrations and insulin resistance in preeclampsia.
Topics: Adult; Case-Control Studies; Female; Homocysteine; Humans; Insulin Resistance; Pre-Eclampsia; Pregnancy; Prospective Studies; Young Adult | 2009 |
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Colorectal Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Pregnancy; Prenatal Nutritional Physiological Phenomena; Random Allocation; Thymine Nucleotides; Uridine Triphosphate; Weaning | 2009 |
Maternal serum homocysteine and risk for neural tube defects in a Texas-Mexico border population.
Topics: Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Mexico; Neural Tube Defects; Pregnancy; Pregnancy Complications; Retrospective Studies; Risk Factors; Texas; Vitamin B 12 | 2009 |
IVF outcomes are associated with biomarkers of the homocysteine pathway in monofollicular fluid.
Topics: Biomarkers; Female; Fertilization in Vitro; Folic Acid; Follicular Fluid; Homocysteine; Humans; Pregnancy; Pregnancy Rate; Sperm Injections, Intracytoplasmic; Vitamin B 12 | 2009 |
Folic acid supplementation provided in utero and during lactation reduces the number of terminal end buds of the developing mammary glands in the offspring.
Topics: Animal Feed; Animals; Dietary Supplements; Female; Folic Acid; Homocysteine; Lactation; Male; Mammary Glands, Animal; Maternal Exposure; Pregnancy; Rats; Rats, Sprague-Dawley; Time Factors; Vitamins | 2009 |
Protein restriction in pregnant- and lactating rats-induced oxidative stress and hypohomocysteinaemia in their offspring.
Topics: Animals; Birth Weight; Dietary Proteins; Eating; Female; Glutathione; Homocysteine; Lactation; Oxidative Stress; Pregnancy; Rats; Rats, Wistar | 2009 |
Vasculopathic and thrombophilic risk factors for spontaneous preterm birth.
Topics: Adult; Case-Control Studies; Cholesterol, HDL; Coronary Disease; Enzyme-Linked Immunosorbent Assay; Female; Gestational Age; Homocysteine; Humans; Infant, Newborn; Placenta; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications, Cardiovascular; Premature Birth; Prospective Studies; Risk Factors; Stroke; Young Adult | 2009 |
Folate and homocysteine phenotypes: Comparative findings using research and clinical laboratory data.
Topics: Adult; Chromatography, Liquid; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Mass Spectrometry; Middle Aged; Phenotype; Pregnancy; Reproducibility of Results; Sensitivity and Specificity; Young Adult | 2009 |
Association of maternal serum CRP, IL-6, TNF-alpha, homocysteine, folic acid and vitamin B12 levels with the severity of preeclampsia and fetal birth weight.
Topics: Adult; Biomarkers; Birth Weight; C-Reactive Protein; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Infant, Low Birth Weight; Infant, Newborn; Interleukin-6; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Tumor Necrosis Factor-alpha; Vitamin B 12; Young Adult | 2009 |
Association of paraoxonase 55 and 192 gene polymorphisms on serum homocysteine concentrations in preeclampsia.
Topics: Adult; Aryldialkylphosphatase; Female; Genotype; Homocysteine; Humans; Male; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Young Adult | 2009 |
Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death.
Topics: Animals; Cell Death; Cells, Cultured; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Homocysteine; MAP Kinase Signaling System; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2009 |
Pilot study of association of anembryonic pregnancy with 55 elements in the urine, and serum level of folate, homocysteine and S-adenosylhomocysteine in Shanxi Province, China.
Topics: Adult; Case-Control Studies; China; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Multivariate Analysis; Nutritional Status; Pilot Projects; Pregnancy; Pregnancy Outcome; S-Adenosylhomocysteine; Trace Elements; Urine; Young Adult | 2009 |
Effects of hyperhomocysteinemia on arterial pressure and nitric oxide production in pregnant rats.
Topics: Animals; Blood Pressure; Female; Homocysteine; Hyperhomocysteinemia; Nitric Oxide; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Rats | 2009 |
Homocysteine and cysteine concentrations are modified by recent exposure to environmental air pollution in São Paulo, Brazil.
Topics: Air Pollutants; Animals; Brazil; Cysteine; Environmental Exposure; Female; Homocysteine; Linear Models; Male; Maternal Exposure; Mice; Models, Animal; Pregnancy; Urban Population; Vehicle Emissions | 2009 |
Zinc antagonizes homocysteine-induced fetal heart defects in rats.
Topics: Animals; Female; Fetal Heart; Heart Defects, Congenital; Homocysteine; Pregnancy; Rats; Rats, Sprague-Dawley; Zinc | 2009 |
[Laboratory evaluation of endothelial function in term neonatal infants born to mothers with gestosis].
Topics: Case-Control Studies; Endothelial Cells; Endothelium, Vascular; Female; Homocysteine; Humans; Infant, Newborn; Nitric Oxide; Oxidative Stress; Pre-Eclampsia; Pregnancy; Term Birth; Tyrosine | 2009 |
Novel mechanism causing restricted fetal growth: does maternal homocysteine impair placental amino acid transport?
Topics: Amino Acid Transport Systems; Biological Transport, Active; Cell Membrane; Female; Fetal Development; Fetal Growth Retardation; Homocysteine; Humans; Microvilli; Placenta; Pregnancy | 2009 |
LINE-1 DNA methylation is inversely correlated with cord plasma homocysteine in man: a preliminary study.
Topics: DNA Methylation; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Long Interspersed Nucleotide Elements; Pregnancy | 2009 |
Association of congenital cardiovascular malformations with 33 single nucleotide polymorphisms of selected cardiovascular disease-related genes.
Topics: Aortic Coarctation; Aortic Valve Stenosis; Blood Coagulation; Blood Pressure; Cell Communication; Dietary Supplements; Female; Heart Defects, Congenital; Heart Septal Defects, Atrial; Homocysteine; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Prospective Studies; Pulmonary Valve Stenosis; Racial Groups | 2010 |
Association of homocysteine, asymmetric dimethylarginine, and nitric oxide with preeclampsia.
Topics: Arginine; Biomarkers; Case-Control Studies; Chromatography, Liquid; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Nitric Oxide; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Tandem Mass Spectrometry | 2010 |
Subclinical vitamin B12 deficiency in pregnant women attending an antenatal clinic in Nigeria.
Topics: Adult; Ambulatory Care Facilities; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Methylmalonic Acid; Nigeria; Pregnancy; Pregnancy Complications; Prenatal Care; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2009 |
Double aneuploidy (48,XXY,+21) of maternal origin in a child born to a 13-year-old mother: evaluation of the maternal folate metabolism.
Topics: Adolescent; Alleles; Aneuploidy; Brazil; Chromosomes, Human, X; Chromosomes, Human, Y; DNA Mutational Analysis; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Carrier Screening; Genotype; Heart Defects, Congenital; Homocysteine; Homozygote; Humans; Infant; Klinefelter Syndrome; Male; Meiosis; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Nondisjunction, Genetic; Polymorphism, Genetic; Pregnancy; Pregnancy in Adolescence; Sex Chromosome Aberrations; Trisomy | 2009 |
Methionine metabolism in human pregnancy.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Homocysteine; Humans; Methionine; Methylation; Pregnancy; Statistics, Nonparametric; Young Adult | 2010 |
Supplementation of a maternal low-protein diet in rat pregnancy with folic acid ameliorates programming effects upon feeding behaviour in the absence of disturbances to the methionine-homocysteine cycle.
Topics: Animals; Appetite Regulation; Caseins; Diet, Protein-Restricted; Dietary Fats; Dietary Supplements; DNA Methylation; Enzymes; Female; Folic Acid; Food Preferences; Glutathione; Homocysteine; Male; Methionine; Placentation; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Rats; Rats, Wistar; RNA, Messenger; Vitamin B Complex | 2010 |
Effects of hyperhomocysteinemia during the gestational period on ossification in rat embryo.
Topics: Animals; Animals, Newborn; Bone Diseases, Metabolic; Female; Gestational Age; Growth Plate; Homocysteine; Hyperhomocysteinemia; Male; Microscopy; Osteogenesis; Pregnancy; Pregnancy Complications; Radius; Rats; Rats, Sprague-Dawley; Spine; Tibia | 2010 |
Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat.
Topics: Animals; Body Weight; Cell Lineage; Choline; Deficiency Diseases; Enteroendocrine Cells; Female; Fetal Development; Folic Acid; Gastric Mucosa; Ghrelin; Growth Hormone; Homocysteine; Immunohistochemistry; Pregnancy; Rats; Rats, Wistar; Vitamin B 12; Weaning | 2010 |
Biochemical, biometrical and behavioral changes in male offspring of sleep-deprived mice.
Topics: Animals; Animals, Newborn; Corticosterone; Cysteine; Embryonic Development; Estradiol; Female; Homocysteine; Litter Size; Male; Maze Learning; Mice; Motor Activity; Organ Size; Pregnancy; Pregnancy Maintenance; Progesterone; Sex Ratio; Sleep Deprivation; Superoxide Dismutase; Time Factors | 2010 |
[Side effects of caffeine].
Topics: Abortion, Spontaneous; Arteries; Caffeine; Cholesterol; Coronary Disease; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 2; DNA Copy Number Variations; Elasticity; Esophageal Sphincter, Lower; Female; Fetal Growth Retardation; Glucose; Homocysteine; Humans; Hypertension; Insulin Resistance; Pregnancy; Risk Factors | 2009 |
Clinical differences between early-onset HELLP syndrome and early-onset preeclampsia during pregnancy and at least 6 months postpartum.
Topics: Adult; Eclampsia; Factor V; Female; Heart Rate; HELLP Syndrome; Homocysteine; Humans; Hypercholesterolemia; Hyperglycemia; Hypertension; Hypertriglyceridemia; Mutation; Obesity; Postpartum Period; Pre-Eclampsia; Pregnancy; Proteinuria; Prothrombin; Thrombophilia | 2010 |
Expression of folate transporters in human placenta and implications for homocysteine metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Carrier Proteins; Cell Membrane; Cell Polarity; Cystathionine beta-Synthase; Female; Fluorescent Antibody Technique, Indirect; Folate Receptors, GPI-Anchored; Folic Acid; Homocysteine; Humans; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Placenta; Pregnancy; Pregnancy Proteins; Pregnancy Trimester, First; Protein Transport; Proton-Coupled Folate Transporter; Receptors, Cell Surface; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Term Birth; Trophoblasts | 2010 |
Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice.
Topics: Animals; Choline; Diet; Female; Fetal Heart; Heart; Heart Defects, Congenital; Homocysteine; Lipotropic Agents; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Pregnancy; Pregnancy Outcome; Prenatal Nutritional Physiological Phenomena; Riboflavin; Vitamin B Complex | 2010 |
Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects.
Topics: Adult; Base Sequence; DNA Methylation; Educational Status; Embryonic Development; Female; Genome, Human; Homocysteine; Humans; Immunoassay; Long Interspersed Nucleotide Elements; Male; Malnutrition; Molecular Sequence Data; Neural Tube Defects; Open Reading Frames; Parity; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Young Adult | 2010 |
Maternal homocysteine and related B vitamins as risk factors for low birthweight.
Topics: Adult; Chromatography, Liquid; Female; Homocysteine; Humans; Infant, Low Birth Weight; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Maternal-Fetal Exchange; Pregnancy; Prospective Studies; Regression Analysis; Risk Factors; Surveys and Questionnaires; Tandem Mass Spectrometry; Vitamin B Complex | 2010 |
Troponin I and homocysteine levels in mild and severe preeclampsia.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Immunoassay; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Troponin I | 2010 |
Homocysteine in small-for-gestational age and appropriate-for-gestational age preterm neonates from mothers receiving folic acid supplementation.
Topics: Adult; Birth Weight; Female; Fetal Blood; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Gestational Age; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Mothers; Predictive Value of Tests; Pregnancy; Premature Birth; Vitamin B 12 | 2010 |
Positive newborn screen for methylmalonic aciduria identifies the first mutation in TCblR/CD320, the gene for cellular uptake of transcobalamin-bound vitamin B(12).
Topics: Amino Acid Sequence; Antigens, CD; Base Sequence; Cells, Cultured; DNA Mutational Analysis; Female; Fibroblasts; Homocysteine; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methylmalonic Acid; Molecular Sequence Data; Mutation; Neonatal Screening; Pregnancy; Receptors, Cell Surface; Transcobalamins; Vitamin B 12 | 2010 |
Genetic and lifestyle variables associated with homocysteine concentrations and the distribution of folate derivatives in healthy premenopausal women.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Black or African American; Child; Child, Preschool; Dietary Supplements; Erythrocytes; Female; Genetic Association Studies; Homocysteine; Humans; Infant; Life Style; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Pregnancy; Premenopause; Spinal Dysraphism; Tetrahydrofolates; Thymidylate Synthase; Vitamins; White People; Young Adult | 2010 |
Serum vitamin B12 and homocysteine levels in pregnant women with neural tube defect.
Topics: Adult; Case-Control Studies; Female; Fetal Diseases; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Neural Tube Defects; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2010 |
Homocysteine, red cell, and plasma folate concentrations and birth weight in Italian women: results from a prospective study.
Topics: Adult; Birth Weight; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Gestational Age; Homocysteine; Humans; Infant, Newborn; Italy; Osmolar Concentration; Plasma; Pregnancy; Prospective Studies; Young Adult | 2011 |
Negative correlation between D-dimer and homocysteine levels during pregnancy and the postpartum period: a prospective study.
Topics: Adult; Dimerization; Female; Fibrin Fibrinogen Degradation Products; Homocysteine; Humans; Postpartum Period; Pregnancy; Prospective Studies; Venous Thromboembolism; Young Adult | 2010 |
Association of omega-3 fatty acids and homocysteine concentrations in pre-eclampsia.
Topics: Adult; Erythrocytes; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Folic Acid; Homocysteine; Humans; India; Life Style; Pre-Eclampsia; Pregnancy; Prenatal Nutritional Physiological Phenomena; Prospective Studies; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2011 |
Vitamin B12 and folic acid supplementation and plasma total homocysteine concentrations in pregnant Indian women with low B12 and high folate status.
Topics: Adult; Dietary Supplements; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Rural Population; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Relationships between pregnancy outcomes, biochemical markers and pre-pregnancy body mass index.
Topics: Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Democratic People's Republic of Korea; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Obesity; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Risk Factors; Socioeconomic Factors; Weight Gain | 2011 |
Quantitative, high-resolution epigenetic profiling of CpG loci identifies associations with cord blood plasma homocysteine and birth weight in humans.
Topics: Birth Weight; CpG Islands; Epigenesis, Genetic; Female; Fetal Blood; Folic Acid; Gene Expression Profiling; Homocysteine; Humans; Long Interspersed Nucleotide Elements; Male; Neural Tube Defects; Pregnancy; Vitamin B Complex | 2011 |
Maternal homocysteine level and markers used in first-trimester screening for fetal Down syndrome.
Topics: Adult; Biomarkers; Chorionic Gonadotropin, beta Subunit, Human; Down Syndrome; Female; Gestational Age; Homocysteine; Humans; Nuchal Translucency Measurement; Pregnancy; Pregnancy-Associated Plasma Protein-A; Prenatal Diagnosis | 2010 |
Asymmetric dimethylarginine concentrations are elevated in women with gestational diabetes.
Topics: Adolescent; Adult; Arginine; C-Reactive Protein; Diabetes, Gestational; Female; Homocysteine; Humans; Insulin Resistance; Pregnancy; Pregnancy Trimester, Third; Young Adult | 2010 |
Homocysteine, folic acid and vitamin B12 levels in maternal and umbilical cord plasma and homocysteine levels in placenta in pregnant women with pre-eclampsia.
Topics: Adult; Case-Control Studies; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Placenta; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Vitamin B 12 | 2011 |
Global DNA methylation patterns in placenta and its association with maternal hypertension in pre-eclampsia.
Topics: Blood Pressure; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hypertension; Infant, Newborn; Mothers; Placenta; Pre-Eclampsia; Pregnancy; Premature Birth; Term Birth; Vitamin B 12 | 2011 |
Oxidative stress elevated DNA damage and homocysteine level in normal pregnant women in a segment of Pakistani population.
Topics: Adult; Aspartate Aminotransferases; Body Temperature; Cholesterol; Cross-Sectional Studies; DNA Damage; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Immunoenzyme Techniques; Oxidative Stress; Pakistan; Pregnancy; Thyroxine; Triiodothyronine | 2011 |
Maternal and cord blood homocysteine and folic acid levels in smoking and nonsmoking pregnant women.
Topics: Adult; Female; Fetal Blood; Folic Acid; Gestational Age; Homocysteine; Humans; Luminescent Measurements; Pregnancy; Prenatal Exposure Delayed Effects; Smoking | 2011 |
A derangement of the maternal lipid profile is associated with an elevated risk of congenital heart disease in the offspring.
Topics: Adult; Apolipoproteins B; Body Mass Index; Case-Control Studies; Child; Cholesterol, LDL; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Hyperglycemia; Hyperhomocysteinemia; Logistic Models; Multivariate Analysis; Odds Ratio; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Young Adult | 2012 |
No relation between folate and homocysteine levels and depression in early pregnant women.
Topics: Adult; Cross-Sectional Studies; Depression; Diet; Female; Folic Acid; Homocysteine; Humans; Japan; Odds Ratio; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Psychiatric Status Rating Scales; Vitamin B 12; Vitamin B 6 | 2010 |
Physiologic changes in homocysteine metabolism in pregnancy: a longitudinal study in Spain.
Topics: Adult; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Genotype; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Nutrition Policy; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Prevalence; Spain; Vitamin B 12 | 2011 |
Frequency of hereditary thrombophilia, anticoagulant activity, and homocysteine levels in patients with hemolysis, elevated liver functions and low thrombocyte count (HELLP) syndrome.
Topics: Adolescent; Adult; Antithrombin III; Blood Coagulation Factor Inhibitors; Blood Coagulation Factors; Female; HELLP Syndrome; Homocysteine; Humans; Pregnancy; Protein C; Protein S; Thrombophilia; Turkey; Young Adult | 2011 |
Hyperhomocysteinaemia, vascular related pregnancy complications and the response to vitamin supplementation in pregnant women of Pakistan.
Topics: Abruptio Placentae; Case-Control Studies; Cohort Studies; Eclampsia; Female; Folic Acid; Gestational Age; Homocysteine; Hospitals, Teaching; Humans; Hyperhomocysteinemia; Pakistan; Pregnancy; Pregnancy Outcome; Vitamin B 6; Vitamin B Complex | 2010 |
Effects of altered maternal folic acid, vitamin B12 and docosahexaenoic acid on placental global DNA methylation patterns in Wistar rats.
Topics: Animals; Diet; DNA Methylation; Docosahexaenoic Acids; Fatty Acids; Feeding Behavior; Female; Folic Acid; Homocysteine; Placenta; Pregnancy; Rats; Reproduction; Vitamin B 12 | 2011 |
A longitudinal study of maternal folate and vitamin B12 status in pregnancy and postpartum, with the same infant markers at 6 months of age.
Topics: Adult; Australia; Biomarkers; Breast Feeding; Cross-Sectional Studies; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Infant; Longitudinal Studies; Luminescent Measurements; Postpartum Period; Pregnancy; Pregnancy Complications; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2012 |
A maternal dietary pattern characterised by fish and seafood in association with the risk of congenital heart defects in the offspring.
Topics: Adult; Biomarkers; Case-Control Studies; Feeding Behavior; Female; Fish Products; Heart Defects, Congenital; Homocysteine; Humans; Methylation; Netherlands; Odds Ratio; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Seafood; Surveys and Questionnaires; Vitamin B Complex | 2011 |
Maternal folate, vitamin B12 and homocysteine levels in pregnancies affected by congenital malformations other than neural tube defects.
Topics: Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Risk Factors; Vitamin B 12 | 2011 |
In vitro effects of L-arginine on spontaneous and homocysteine-induced contractility of pregnant canine uteri.
Topics: Animals; Arginine; Dogs; Dose-Response Relationship, Drug; Female; Homocysteine; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pregnancy; Uterine Contraction; Uterus | 2011 |
Elevated maternal serum folate in the third trimester and reduced fetal growth: a longitudinal study.
Topics: Adult; Biomarkers; Birth Weight; Body Height; Dietary Supplements; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Infant; Longitudinal Studies; Nutritional Status; Pregnancy; Pregnancy Trimester, Third; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Pyridoxal; Vitamin B 12; Vitamin B Complex; Weight Gain | 2011 |
Soya protein- and casein-based nutritionally complete diets fed during gestation and lactation differ in effects on characteristics of the metabolic syndrome in male offspring of Wistar rats.
Topics: Animals; Animals, Newborn; Body Composition; Caseins; Female; Fetal Development; Glucose; Homocysteine; Hyperglycemia; Hypertension; Insulin Resistance; Lactation; Male; Maternal Nutritional Physiological Phenomena; Metabolic Syndrome; Pregnancy; Random Allocation; Rats; Rats, Wistar; Soybean Proteins; Weaning; Weight Gain | 2012 |
Time for a rethink of vitamin B12 injections?
Topics: Administration, Oral; Developing Countries; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Injections, Intramuscular; New Zealand; Pregnancy; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Homocysteine homeostasis in the rat is maintained by compensatory changes in cystathionine β-synthase, betaine-homocysteine methyltransferase, and phosphatidylethanolamine N-methyltransferase gene transcription occurring in response to maternal protein an
Topics: Animal Nutritional Physiological Phenomena; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Diet; Diet, High-Fat; Diet, Protein-Restricted; Dietary Fats; Dietary Proteins; Dietary Supplements; Down-Regulation; Female; Folic Acid; Gene Expression; Homeostasis; Homocysteine; Liver; Male; Methionine; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Pregnancy; Prenatal Nutritional Physiological Phenomena; Rats, Wistar; Vitamin B Complex; Weaning | 2011 |
Uptake of cobalamin and markers of cobalamin status: a longitudinal study of healthy pregnant women.
Topics: Adult; Biomarkers; Denmark; Female; Homocysteine; Humans; Longitudinal Studies; Methylmalonic Acid; Pregnancy; Pregnancy Trimesters; Transcobalamins; Vitamin B 12 | 2011 |
Folate, vitamin B12, vitamin B6 and homocysteine: impact on pregnancy outcome.
Topics: Adult; Biomarkers; Dietary Supplements; DNA Damage; Erythrocyte Count; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Logistic Models; Multivariate Analysis; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Prospective Studies; South Australia; Vitamin B 12; Vitamin B 6 | 2013 |
Folic acid supplements modify the adverse effects of maternal smoking on fetal growth and neonatal complications.
Topics: Adult; Birth Weight; Dietary Supplements; Female; Fetal Development; Fetal Weight; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; Netherlands; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Premature Birth; Prospective Studies; Smoking; Young Adult | 2011 |
The Ottawa and Kingston (OaK) Birth Cohort: development and achievements.
Topics: Canada; Cohort Studies; Dietary Supplements; Female; Fetal Blood; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Newborn; Maternal Nutritional Physiological Phenomena; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Prenatal Care; Prospective Studies; Thrombophilia; Vitamins | 2011 |
Variability of total thiol compounds, oxidative and nitrosative stress in uncomplicated pregnant women and nonpregnant women.
Topics: Adult; Cysteine; Female; Homocysteine; Humans; Lipid Peroxidation; Nitric Oxide; Oxidative Stress; Pregnancy; Young Adult | 2012 |
[Protective effects and its mechanism on neural cells after folic acid intervention in preeclampsia rat model].
Topics: Animals; Apoptosis; Disease Models, Animal; Female; Folic Acid; Homocysteine; Male; Neurons; Neuroprotective Agents; NF-kappa B; Pre-Eclampsia; Pregnancy; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Sodium Glutamate | 2011 |
Methylenetetrahydrofolate reductase gene 677CT polymorphism and isolated congenital heart disease in a Mexican population.
Topics: Adolescent; Adult; Alleles; Child; Child, Preschool; DNA; Female; Folic Acid; Gene Frequency; Heart Defects, Congenital; Homocysteine; Humans; Infant; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Polymerase Chain Reaction; Polymorphism, Genetic; Pregnancy; Prenatal Care; Young Adult | 2012 |
Effect on risk of anencephaly of gene-nutrient interactions between methylenetetrahydrofolate reductase C677T polymorphism and maternal folate, vitamin B12 and homocysteine profile.
Topics: Adult; Anencephaly; Case-Control Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Polymorphism, Genetic; Pregnancy; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2012 |
Serum homocysteine level and its association with folic acid and vitamin B12 in the third trimester of pregnancies complicated with intrauterine growth restriction.
Topics: Adult; Female; Fetal Growth Retardation; Fetal Weight; Folic Acid; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, Third; Vitamin B 12; Young Adult | 2011 |
Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARα, interferon-γ, and interleukin-10.
Topics: Animals; Apolipoprotein A-I; Choline Deficiency; DNA Methylation; Female; Gene Expression; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Inflammation Mediators; Interferon-gamma; Interleukin-10; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Knockout; Muscle Spasticity; Placenta; PPAR alpha; Pregnancy; Pregnancy Complications; Promoter Regions, Genetic; Psychotic Disorders; RNA, Messenger | 2012 |
The association between homocysteine in the follicular fluid with embryo quality and pregnancy rate in assisted reproductive techniques.
Topics: Adult; Embryo Transfer; Estradiol; Female; Follicular Fluid; Homocysteine; Humans; Infertility, Female; Male; Oocytes; Pregnancy; Pregnancy Rate; Reproductive Techniques, Assisted; Sperm Injections, Intracytoplasmic | 2012 |
Solute Carrier Family 19, member 1 (SLC19A1) polymorphisms (-43T>C, 80G>A, and 696C>T), and haplotypes in idiopathic recurrent spontaneous abortion in a Korean population.
Topics: Abortion, Habitual; Adult; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; Homocysteine; Humans; Korea; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pregnancy; Reduced Folate Carrier Protein; Risk Factors | 2012 |
The Mediterranean diet and fetal size parameters: the Generation R Study.
Topics: Adult; Birth Weight; C-Reactive Protein; Diet, Mediterranean; Energy Intake; Feeding Behavior; Female; Fetal Development; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Logistic Models; Netherlands; Organ Size; Patient Compliance; Placenta; Pregnancy; Prenatal Nutritional Physiological Phenomena; Prospective Studies; Qualitative Research; Surveys and Questionnaires; Vitamin B 12; White People | 2012 |
Circulating levels of homocysteine in preeclamptic women.
Topics: Adult; Cross-Sectional Studies; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy | 2011 |
Pregnancy and a rare MTHFR haplotype.
Topics: Adult; Female; Folic Acid; Haplotypes; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications | 2012 |
Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice.
Topics: Aminohydrolases; Animals; Choline; Choline Deficiency; Crosses, Genetic; Disease Models, Animal; Embryo Loss; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Formate-Tetrahydrofolate Ligase; Genes, Lethal; Heterozygote; Homocysteine; Hypoxanthine; Maternal Nutritional Physiological Phenomena; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Mutant Strains; Multienzyme Complexes; Mutagenesis, Insertional; Neural Tube Defects; Pregnancy | 2012 |
Plasma homocysteine concentrations in mothers and term and preterm newborns.
Topics: Adult; Female; Gestational Age; Homocysteine; Humans; Infant, Newborn; Infant, Premature; Mothers; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Reference Values; Vitamin B 12; Young Adult | 2011 |
Effects of methyl-deficient diets on methionine and homocysteine metabolism in the pregnant rat.
Topics: Animals; Choline; Cysteine; Diet; Female; Fetus; Folic Acid; Homocysteine; Kinetics; Litter Size; Liver; Methionine; Methylation; Pancreas; Phosphorylcholine; Placenta; Pregnancy; Rats; Triglycerides; Weight Gain | 2012 |
Homocysteine and folate concentrations in early pregnancy and the risk of adverse pregnancy outcomes: the Generation R Study.
Topics: Adult; Birth Weight; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Netherlands; Organ Size; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Risk Factors; Vitamin B 12; Young Adult | 2012 |
Evaluation of serum ischemia-modified albumin levels in pregnant women with and without gestational diabetes mellitus.
Topics: Adult; Biomarkers; Diabetes, Gestational; Female; Homocysteine; Humans; Hypoglycemic Agents; Infusions, Subcutaneous; Insulin; Nutrition Therapy; Pregnancy; Regression Analysis; Serum Albumin; Serum Albumin, Human; Young Adult | 2012 |
The influence of homocysteine and oxidative stress on pregnancy outcome.
Topics: Biomarkers; C-Reactive Protein; Ceruloplasmin; Female; Homocysteine; Humans; Hyperhomocysteinemia; Malondialdehyde; Oxidative Stress; Placenta Diseases; Pregnancy; Pregnancy Outcome; Romania; Uric Acid | 2012 |
Effects of alcohol, lithium, and homocysteine on nonmuscle myosin-II in the mouse placenta and human trophoblasts.
Topics: Animals; Cell Line; Cell Movement; Central Nervous System Depressants; Endothelial Cells; Ethanol; Female; Folic Acid; Homocysteine; Humans; Inositol; Lithium Compounds; Maternal Exposure; Mice; Nonmuscle Myosin Type IIA; Nonmuscle Myosin Type IIB; Placenta; Placental Circulation; Pregnancy; Trophoblasts; Ultrasonography, Doppler; Umbilical Cord; Vitamin B Complex | 2012 |
Reduced folate, increased vitamin B(12) and homocysteine concentrations in women delivering preterm.
Topics: Adult; Birth Weight; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Maternal Nutritional Physiological Phenomena; Micronutrients; Nutrition Assessment; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Premature Birth; Vitamin B 12; Vitamin B Complex; Young Adult | 2012 |
Homocysteine, folate and pregnancy outcomes.
Topics: Adult; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Logistic Models; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 2012 |
The role of homocysteine, asymmetric dimethylarginine and nitric oxide in pre-eclampsia.
Topics: Adult; Arginine; Case-Control Studies; Female; Homocysteine; Humans; Nitric Oxide; Pre-Eclampsia; Pregnancy; Young Adult | 2012 |
Homocysteine, folate, vitamin B12 and B6 in mothers of children with neural tube defects in Xinjiang, China.
Topics: Adult; Biomarkers; Case-Control Studies; China; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Risk Factors; Vitamin B 12; Vitamin B 6 | 2012 |
Maternal B vitamin status in pregnancy week 18 according to reported use of folic acid supplements.
Topics: Adult; Biomarkers; Dietary Supplements; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Micronutrients; Norway; Pregnancy; Prospective Studies; Riboflavin; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2013 |
Antiepileptic drugs and the fetal epigenome.
Topics: Anticonvulsants; Birth Weight; Case-Control Studies; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Epilepsy; Female; Fetal Blood; Fetus; Folic Acid; Homocysteine; Humans; Oligonucleotide Array Sequence Analysis; Pregnancy; Pregnancy Complications | 2013 |
Value of homocysteine levels, troponin I, and score for neonatal acute physiology and perinatal extension II as early predictors of morbidity.
Topics: APACHE; Female; Fetal Blood; Homocysteine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Male; Pre-Eclampsia; Pregnancy; Prognosis; Regression Analysis; ROC Curve; Troponin I | 2012 |
Positive correlation between serum levels of adiponectin and homocysteine in pre-eclampsia.
Topics: Adiponectin; Adult; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy | 2013 |
Effects of homocysteine on ERK signaling and cell proliferation in fetal neural stem cells in vitro.
Topics: Animals; Apoptosis; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Female; Fetal Stem Cells; Homocysteine; MAP Kinase Signaling System; Neural Stem Cells; Phosphorylation; Pregnancy; Rats; SOXB1 Transcription Factors | 2013 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
Why is homocysteine toxic for the nervous and immune systems?
Topics: Animals; Brain Ischemia; Carnosine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Neuroimmunomodulation; Neuroprotective Agents; Parkinson Disease; Pregnancy; Rats; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2013 |
Differences in the association between maternal serum homocysteine and ADMA levels in women with pregnancies complicated by preeclampsia and/or intrauterine growth restriction.
Topics: Adult; Arginine; Case-Control Studies; Female; Fetal Growth Retardation; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Young Adult | 2013 |
Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study.
Topics: Betaine; Child Development; Child, Preschool; Choline; Cognition; Female; Homocysteine; Humans; Language; Linear Models; Longitudinal Studies; Male; Methionine; Neuropsychological Tests; Nutritional Status; Pregnancy; Sarcosine; Seychelles | 2013 |
Vitamin B(12) intake and status in early pregnancy among urban South Indian women.
Topics: Adolescent; Adult; Anthropometry; Cross-Sectional Studies; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; India; Methylmalonic Acid; Nutritional Status; Parity; Pregnancy; Prevalence; Socioeconomic Factors; Surveys and Questionnaires; Urban Population; Vitamin B 12; Vitamin B 12 Deficiency; White People; Young Adult | 2013 |
Early methyl donor deficiency produces severe gastritis in mothers and offspring through N-homocysteinylation of cytoskeleton proteins, cellular stress, and inflammation.
Topics: Animals; Animals, Newborn; Animals, Suckling; Cadherins; Cytoskeletal Proteins; Female; Fetus; Gastritis; Homocysteine; Inflammation; Methylation; Mothers; Oxidative Stress; Pregnancy; Rats; Rats, Wistar; Severity of Illness Index; Signal Transduction | 2013 |
[Investigation of relationship between pregnancy induced hypertension syndrome and homocysteine, folic acid and vitamin B(12)].
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Vitamin B 12 | 2002 |
Relationship between total homocysteine and folate levels in pregnant women and their newborn babies according to maternal serum levels of vitamin B12.
Topics: Adolescent; Adult; Biomarkers; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Nutritional Status; Pregnancy; Regression Analysis; Vitamin B 12 | 2002 |
Does prenatal screening for 5,10-methylenetetrahydrofolate reductase (MTHFR) mutations in high-risk neural tube defect pregnancies make sense?
Topics: Animals; Female; Fetal Diseases; Folic Acid; Genetic Predisposition to Disease; Genetic Testing; Homocysteine; Humans; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pregnancy; Prenatal Diagnosis | 2002 |
The pregnancy-related decrease in fasting plasma homocysteine is not explained by folic acid supplementation, hemodilution, or a decrease in albumin in a longitudinal study.
Topics: Adolescent; Adult; Blood Volume; Dietary Supplements; Fasting; Female; Folic Acid; Gestational Age; Hematocrit; Homocysteine; Humans; Longitudinal Studies; Pregnancy; Serum Albumin | 2002 |
Low Vitamin B(12) level as a risk factor for very early recurrent abortion.
Topics: Abortion, Habitual; Adult; Dietary Supplements; Female; Gestational Age; Homocysteine; Humans; Pregnancy; Pregnancy Outcome; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Folate levels in pregnant women who smoke: an important gene/environment interaction.
Topics: Adult; Cotinine; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Smoking; Vitamin B 12 | 2002 |
Serum concentrations of homocysteine are elevated during early pregnancy in rodent models of fetal programming.
Topics: Abortion, Spontaneous; Amino Acids; Animals; Blastocyst; Diet, Protein-Restricted; Disease Susceptibility; Embryonic and Fetal Development; Female; Gestational Age; Homocysteine; Methionine; Mice; Mice, Inbred Strains; Models, Animal; Pre-Eclampsia; Pregnancy; Prenatal Nutritional Physiological Phenomena; Rats; Rats, Inbred Strains | 2002 |
Preconception homocysteine and B vitamin status and birth outcomes in Chinese women.
Topics: Adult; Body Mass Index; Body Weight; Case-Control Studies; China; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Small for Gestational Age; Nutritional Status; Obstetric Labor, Premature; Preconception Care; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2002 |
Hyperhomocysteinemia is related to a decreased blood level of vitamin B12 in the second and third trimester of normal pregnancy.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intrinsic Factor; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Receptors, Peptide; Statistics as Topic; Vitamin B 12 | 2002 |
Maternal homocysteine levels and plasma lipids in gestational diabetes: is there any relationship?
Topics: Adult; Biomarkers; Case-Control Studies; Cholesterol; Cholesterol, LDL; Diabetes, Gestational; Female; Homocysteine; Humans; Parity; Pregnancy; Pregnancy Trimester, Third; Triglycerides | 2002 |
Folate delivers head-to-toe health advantages. The B vitamin that benefits unborn babies may also protect the hearts and minds (and colons) of adults.
Topics: Alzheimer Disease; Anencephaly; Colonic Neoplasms; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Male; Pregnancy; Spinal Dysraphism; Stroke | 2002 |
Plasma total cysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine Study.
Topics: Abruptio Placentae; Adult; Congenital Abnormalities; Cysteine; Female; Homocysteine; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Norway; Odds Ratio; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Registries; Risk Factors | 2003 |
Homocysteine is embryotoxic but does not cause neural tube defects in mouse embryos.
Topics: Animals; Central Nervous System; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fetus; Folic Acid; Homocysteine; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Neural Tube Defects; Pregnancy; Pregnancy Complications; Somites; Thymidine | 2003 |
Folate status in Germany 1997-2000.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Diet; Diet Records; Dietary Supplements; Erythrocytes; Female; Folic Acid; Food, Fortified; Germany; Homocysteine; Humans; Infant; Male; Middle Aged; Nutritional Status; Pregnancy | 2002 |
Plasma homocysteine levels correlated to interactions between folate status and methylene tetrahydrofolate reductase gene mutation in women with unexplained recurrent pregnancy loss.
Topics: Abortion, Habitual; Adolescent; Adult; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy | 2003 |
Pregnancy-related decrease in total plasma homocysteine.
Topics: Female; Glomerular Filtration Rate; Homocysteine; Humans; Pregnancy | 2003 |
The 677 C-T methylenetetrahydrofolate reductase mutation does not predict increased maternal homocysteine during pregnancy.
Topics: Adult; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Retrospective Studies | 2003 |
Plasma total homocysteine in uncomplicated pregnancy and in preeclampsia.
Topics: Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Vitamin B 12 | 2003 |
[Effect of homocysteine on the proliferation and differentiation of rat embryo midbrain cell].
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Embryo, Mammalian; Female; Homocysteine; Mesencephalon; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens | 2000 |
Homocysteine and other plasma amino acids in preeclampsia and in pregnancies without complications.
Topics: Adult; Amino Acids; Case-Control Studies; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Data Interpretation, Statistical; Female; Folic Acid; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Vitamin B 12 | 2003 |
Homocysteine induces trophoblast cell death with apoptotic features.
Topics: Antibodies, Monoclonal; Apoptosis; Caspases; Cell Death; Cell Division; Cells, Cultured; Chorionic Gonadotropin; Cytochromes c; Cytoplasm; DNA Fragmentation; Female; Homocysteine; Humans; In Situ Nick-End Labeling; Pregnancy; Trophoblasts | 2003 |
Serum homocysteine levels are increased in women with gestational diabetes mellitus.
Topics: Adult; Blood Glucose; Blood Pressure; Case-Control Studies; Diabetes, Gestational; Female; Folic Acid; Glucose Tolerance Test; Homocysteine; Humans; Male; Pregnancy; Serum Albumin; Uric Acid; Vitamin B 12 | 2003 |
[Do folates and homocysteine have a causal relation with neural tube defects?].
Topics: Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy | 2003 |
Antiphospholipid/antiprotein antibodies, hemostasis-related autoantibodies, and plasma homocysteine as risk factors for a first early pregnancy loss: a matched case-control study.
Topics: Abortion, Spontaneous; Adult; Antibodies, Antiphospholipid; Autoantibodies; Biomarkers; Blood Coagulation Factors; Case-Control Studies; Female; Hemostasis; Homocysteine; Humans; Matched-Pair Analysis; Odds Ratio; Pregnancy; Pregnancy Trimester, First; Risk Factors | 2003 |
Homocysteine-induced enhancement of spontaneous contractions of myometrium isolated from pregnant women.
Topics: Adult; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Muscle Contraction; Myometrium; Obstetric Labor, Premature; Oxytocics; Pregnancy; Uterine Contraction | 2003 |
The search for thrombophilic gene mutations in women with gestational hypertension does not help in predicting poor pregnancy outcome.
Topics: Adult; Factor V; Female; Genetic Predisposition to Disease; HELLP Syndrome; Homocysteine; Humans; Hypertension; Laser-Doppler Flowmetry; Methylenetetrahydrofolate Reductase (NADPH2); Plasminogen Activator Inhibitor 1; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Prothrombin; Risk Factors; Thrombosis; Ultrasonography; Uterus | 2003 |
Fish oil supplementation of rats during pregnancy reduces adult disease risks in their offspring.
Topics: Animals; Blood Glucose; Caseins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dietary Proteins; Dietary Supplements; Female; Fish Oils; Folic Acid; Health Promotion; Homocysteine; Insulin; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Risk Factors; Triglycerides; Vitamin B 12 | 2003 |
Elevated plasma homocysteine in early pregnancy: a risk factor for the development of nonsevere preeclampsia.
Topics: Adult; Case-Control Studies; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Risk Factors; Severity of Illness Index | 2003 |
Homocysteine plasma concentration levels for the prediction of preeclampsia in women with chronic hypertension.
Topics: Adult; Case-Control Studies; Chronic Disease; Female; Homocysteine; Humans; Hypertension; Osmolar Concentration; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Prognosis; Prospective Studies; Sensitivity and Specificity | 2003 |
Mare embryonic resorption and homocysteine.
Topics: Animals; Biomarkers; Female; Fetal Resorption; Homocysteine; Horse Diseases; Horses; Pregnancy; Pregnancy Complications | 2003 |
Endothelial dysfunction in preeclampsia. Increased homocysteine and decreased nitric oxide levels.
Topics: Adult; Biomarkers; Blood Pressure; Endothelium, Vascular; Female; Gestational Age; Homocysteine; Humans; Nitric Oxide; Pre-Eclampsia; Pregnancy; Proteinuria | 2003 |
[Homocysteine level in ovarian follicular fluid or serum as a predictor of successful fertilization].
Topics: Abortion, Habitual; Adult; Biomarkers; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Fertilization in Vitro; Follicular Fluid; Homocysteine; Humans; Infertility, Female; Ovulation Induction; Predictive Value of Tests; Pregnancy; Risk Factors | 2003 |
Effects of the interaction between the C677T 5,10-methylenetetrahydrofolate reductase polymorphism and serum B vitamins on homocysteine levels in pregnant women.
Topics: Adult; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Pregnancy; Radioimmunoassay; Riboflavin; Vitamin B 12; Vitamin B 6 | 2004 |
Cobalamin (vitamin B12) metabolism during pregnancy.
Topics: Adult; Anemia, Megaloblastic; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Vitamin B 12 | 2004 |
Renal handling of homocysteine during normal pregnancy and preeclampsia.
Topics: Cross-Sectional Studies; Female; Gestational Age; Glomerular Filtration Rate; Homocysteine; Humans; Kidney; Longitudinal Studies; Metabolic Clearance Rate; Pre-Eclampsia; Pregnancy | 2004 |
Hematological parameters and cobalamin status in infants born to smoking mothers.
Topics: Adult; Birth Weight; Erythrocyte Count; Female; Folic Acid; Gestational Age; Hemoglobins; Homocysteine; Humans; Infant; Infant, Newborn; Logistic Models; Maternal-Fetal Exchange; Methylmalonic Acid; Pregnancy; Smoking; Vitamin B 12 | 2004 |
Plasma homocysteine in early and late pregnancies complicated with preeclampsia and isolated intrauterine growth restriction.
Topics: Adult; Case-Control Studies; Cohort Studies; Down Syndrome; Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Mass Screening; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Second; Risk Factors | 2004 |
Thiol status and antioxidant capacity in women with a history of severe pre-eclampsia.
Topics: Antioxidants; Case-Control Studies; Cysteine; Dipeptides; Female; Glucosephosphate Dehydrogenase; Glutathione; Homocysteine; Humans; Oxidative Stress; Pre-Eclampsia; Pregnancy; Sulfhydryl Compounds | 2004 |
New approaches towards laboratory diagnosis of isolated sulphite oxidase deficiency.
Topics: Biomarkers; Clinical Laboratory Techniques; Female; Homocysteine; Humans; Mass Spectrometry; Metabolic Diseases; Molybdenum; Oxidoreductases Acting on Sulfur Group Donors; Prealbumin; Pregnancy; Xanthine Dehydrogenase | 2004 |
Perinatal outcome prediction by maternal homocysteine and uterine artery Doppler velocimetry.
Topics: Adult; Arteries; Blood Flow Velocity; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Laser-Doppler Flowmetry; Predictive Value of Tests; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Sensitivity and Specificity; Ultrasonography; Uterus; Vitamin B 12 | 2004 |
The correlation between plasma homocysteine and malondialdehyde levels in preeclampsia.
Topics: Adult; Female; Homocysteine; Humans; Lipid Peroxidation; Lipid Peroxides; Malondialdehyde; Pre-Eclampsia; Pregnancy; Severity of Illness Index | 2003 |
Homocysteine and folic acid are inversely related in black women with preeclampsia.
Topics: Adolescent; Adult; Arteriosclerosis; Black People; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Age; Pennsylvania; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; White People | 2004 |
Maternal metabolic phenotype and risk of Down syndrome: beyond genetics.
Topics: Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Risk Factors; Vitamin B 12 Deficiency | 2004 |
Serum levels of folate, vitamin B12 and homocysteine in complete hydatidiform mole.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hydatidiform Mole; Luminescent Measurements; Pregnancy; Vitamin B 12 | 2004 |
High-density lipoprotein and homocysteine levels correlate inversely in preeclamptic women in northern Nigeria.
Topics: Adult; Case-Control Studies; Cholesterol, HDL; Female; Gestational Age; Homocysteine; Humans; Nigeria; Pre-Eclampsia; Pregnancy | 2004 |
Elevated plasma homocysteine levels in gestational diabetes mellitus.
Topics: Adult; Blood Glucose; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes, Gestational; Female; Folic Acid; Gestational Age; Glucose Tolerance Test; Homocysteine; Humans; Pregnancy; Prospective Studies; Triglycerides; Turkey; Vitamin B 12 | 2004 |
Maternal homocysteine before conception and throughout pregnancy predicts fetal homocysteine and birth weight.
Topics: Adolescent; Adult; Birth Weight; Dietary Supplements; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Labor, Obstetric; Predictive Value of Tests; Pregnancy; Pregnancy Outcome; Pregnancy Trimesters | 2004 |
Prenatal protein restriction does not affect the proliferation and differentiation of rat preadipocytes.
Topics: Adipocytes; Animals; Animals, Newborn; Blood Vessels; Cell Differentiation; Cell Division; Cells, Cultured; Culture Media; Diet, Protein-Restricted; Epididymis; Female; Fetus; Homocysteine; Kidney; Lactation; Male; Methionine; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Stem Cells; Stromal Cells; Subcutaneous Tissue; Taurine; Weaning | 2004 |
Hyperhomocyst(e)inemia and elevated soluble vascular cell adhesion molecule-1 concentrations are associated with an increased risk of preeclampsia.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Odds Ratio; Pre-Eclampsia; Pregnancy; Risk Factors; Vascular Cell Adhesion Molecule-1 | 2004 |
Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine Study.
Topics: Abruptio Placentae; Adult; Alleles; Congenital Abnormalities; Female; Fetal Growth Retardation; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Humans; Logistic Models; Maternal Age; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy, High-Risk; Risk Factors | 2004 |
No association of C677T methylenetetrahydrofolate reductase and an endothelial nitric oxide synthase polymorphism with recurrent pregnancy loss.
Topics: Abortion, Habitual; Adult; Cysteine; Embryo Loss; Endothelium; Female; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Nitric Oxide; Nitric Oxide Synthase; Polymorphism, Genetic; Pregnancy; Threonine | 2004 |
Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency.
Topics: Animals; Animals, Suckling; Betaine; Body Weight; Brain; Disease Models, Animal; Female; Genotype; Homocysteine; Homocystinuria; Lactation; Liver; Male; Maternal-Fetal Exchange; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Organ Size; Pregnancy | 2004 |
Folate and homocysteine levels in pregnancy.
Topics: Adult; Birth Intervals; Female; Folic Acid; Homocysteine; Humans; Pregnancy | 2004 |
Longitudinal change in plasma total homocysteine during pregnancy and postpartum in Brazilian women and its relation with folate status and other factors.
Topics: Brazil; Chromatography, High Pressure Liquid; Diet; Dietary Supplements; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Iron; Longitudinal Studies; Nutritional Status; Postpartum Period; Pregnancy; Socioeconomic Factors; Transferrin; Vitamin B 12 | 2004 |
Homocysteine and folate in pregnancy.
Topics: Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Reference Values | 2004 |
Homocysteine levels in women with antiphospholipid syndrome and normal fertile controls.
Topics: Adult; Antiphospholipid Syndrome; Chromatography, High Pressure Liquid; Female; Fertility; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Pregnancy; Pregnancy Outcome; Vitamin B 6 | 2004 |
Marginal maternal vitamin B12 status increases the risk of offspring with spina bifida.
Topics: Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Pregnancy; Risk Assessment; Risk Factors; Spinal Dysraphism; Vitamin B 12; Vitamin B 6 | 2004 |
Abnormal folic acid-homocysteine metabolism as maternal risk factors for Down syndrome in Japan.
Topics: Adult; Down Syndrome; Female; Folic Acid; Homocysteine; Humans; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Risk Factors; Vitamin B 12; Vitamin B 6 | 2004 |
Serum homocysteine levels after preterm premature rupture of the membranes.
Topics: Adult; Case-Control Studies; Female; Fetal Membranes, Premature Rupture; Homocysteine; Humans; Odds Ratio; Pregnancy; Pregnancy Trimester, Second; Smoking | 2004 |
Homocysteine thiolactone induces apoptosis in cultured human trophoblasts: a mechanism for homocysteine-mediated placental dysfunction?
Topics: Apoptosis; Blotting, Western; Cells, Cultured; Female; Homocysteine; Humans; Placenta; Placenta Diseases; Pregnancy; Time Factors; Trophoblasts | 2004 |
Coffee: for most, it's safe. Coffee has been blamed for everything from moral turpitude to cancer. But none of the bad raps have stuck. Coffee may even be good for you.
Topics: Caffeine; Cardiovascular System; Coffee; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Liver Diseases; Neoplasms; Osteoporosis; Parkinson Disease; Pregnancy | 2004 |
Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population.
Topics: Adolescent; Adult; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Turkey | 2004 |
Unselected women with elevated levels of factor VIII:C or homocysteine are not at increased risk for obstetric complications.
Topics: Adolescent; Adult; Factor VIII; Family Health; Female; Homocysteine; Humans; Pregnancy; Pregnancy Complications; Risk; Thrombophilia | 2004 |
Elevated plasma homocysteine levels in preeclampsia and eclampsia.
Topics: Adult; Blood Chemical Analysis; Case-Control Studies; Eclampsia; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Turkey | 2004 |
[Arteriosclerosis, Barker's hypothesis, homocysteine and bandworm].
Topics: Animals; Arteriosclerosis; Female; Fetal Development; Fetal Diseases; Helminthiasis; Helminths; Homocysteine; Humans; Male; Malnutrition; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Exposure Delayed Effects; Prognosis; Risk Assessment | 2004 |
Uterine artery Doppler and mid-trimester maternal plasma homocysteine in subsequent pre-eclampsia.
Topics: Adolescent; Adult; Arteries; England; Female; Homocysteine; Humans; Laser-Doppler Flowmetry; Middle Aged; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Second; Prenatal Diagnosis; Pulsatile Flow; Regional Blood Flow; Ultrasonography, Prenatal; Uterus | 2004 |
Low ratio of S-adenosylmethionine to S-adenosylhomocysteine is associated with vitamin deficiency in Brazilian pregnant women and newborns.
Topics: Adult; Birth Weight; Brazil; Female; Fetal Blood; Gestational Age; Homocysteine; Humans; Infant, Newborn; Pregnancy; ROC Curve; S-Adenosylhomocysteine; S-Adenosylmethionine; Social Class; Vitamin B 12 Deficiency | 2004 |
[Recurrent spontaneous miscarriages and hyperhomocysteinemia].
Topics: Abortion, Habitual; Adult; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Pregnancy; Pregnancy Trimester, First | 2004 |
Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency.
Topics: Cystathionine; Cystatin C; Cystatins; Female; Folic Acid; HELLP Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Methylmalonic Acid; Oxidative Stress; Placental Insufficiency; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Uric Acid; Vitamin B 12; Vitamin B 6 | 2004 |
The risk of folate and vitamin B(12) deficiencies associated with hyperhomocysteinemia among pregnant women.
Topics: Adolescent; Adult; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Korea; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Hormone profiles and clinical outcome after laparoscopic ovarian drilling in women with polycystic ovary syndrome.
Topics: Cholesterol; Clomiphene; Female; Fertility Agents, Female; Gynecologic Surgical Procedures; Homocysteine; Hormones; Humans; Infertility, Female; Laparoscopy; Ovulation; Polycystic Ovary Syndrome; Pregnancy | 2005 |
Homocysteine is lower in the third trimester of pregnancy in women with enhanced folate status from continued folic acid supplementation.
Topics: Adolescent; Adult; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Pregnancy; Pregnancy Trimester, Third | 2005 |
Congenital heart defects and abnormal maternal biomarkers of methionine and homocysteine metabolism.
Topics: Adult; Arkansas; Biomarkers; Case-Control Studies; Female; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Life Style; Methionine; Pregnancy; Registries; Risk Factors; S-Adenosylhomocysteine | 2005 |
Stroke and recurrent pregnancy loss due to hyperhomocysteinaemia.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Abortion, Habitual; Brain; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Infarction, Middle Cerebral Artery; Middle Aged; Mutation; Platelet Aggregation Inhibitors; Pregnancy; Stroke; Treatment Outcome; Vitamin B 12 | 2005 |
Post gravidic superior sagittal sinus thrombosis with elevated levels of homocystinemia.
Topics: Adult; Female; Homocysteine; Humans; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Sagittal Sinus Thrombosis | 2004 |
Diagnostic issues in thrombophilia: a laboratory scientist's view.
Topics: Antithrombins; Blood Coagulation Tests; Chemistry, Clinical; Female; Hematologic Tests; Hematology; Homocysteine; Humans; Male; Mutation; Pregnancy; Protein C; Protein S; Risk; Risk Factors; Thrombophilia; Thrombosis | 2005 |
Elevated plasma homocysteine levels in gestational diabetes mellitus.
Topics: Adult; Body Mass Index; Diabetes, Gestational; Female; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Age; Pregnancy | 2005 |
Are plasma total homocysteine and other amino acids associated with glucose intolerance in uncomplicated pregnancies and preeclampsia?
Topics: Adult; Alanine; Amino Acids; Diabetes, Gestational; Female; Glucose Intolerance; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Prospective Studies; Vitamin B Complex | 2005 |
Re: Influence of body weight on plasma homocysteine in preeclampsia.
Topics: Body Mass Index; Body Weight; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy | 2005 |
Mild neonatal hypoxia exacerbates the effects of vitamin-deficient diet on homocysteine metabolism in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Animals, Newborn; Avitaminosis; Base Sequence; Cystathionine beta-Synthase; Female; Homocysteine; Hypoxia; Maternal-Fetal Exchange; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; RNA, Messenger | 2005 |
Polymorphisms of genes involved in homocysteine metabolism in preeclampsia and in uncomplicated pregnancies.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Case-Control Studies; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Vitamin B 12 | 2005 |
Maternal antioxidant concentrations after uncomplicated pregnancies.
Topics: Adult; Antioxidants; Ascorbic Acid; Cysteine; Fasting; Female; Glutathione; Homocysteine; Humans; Lipid Peroxidation; Models, Statistical; Mothers; Oxidative Stress; Oxygen; Postpartum Period; Pregnancy; Sulfhydryl Compounds; Time Factors; Vitamin E | 2005 |
Correlation between maternal plasma homocysteine and zinc levels in preeclamptic women.
Topics: Adult; Copper; Female; Homocysteine; Humans; Hyperhomocysteinemia; Labor Stage, First; Pre-Eclampsia; Pregnancy; Zinc | 2005 |
Cardiology patient pages. Homocysteine and MTHFR mutations: relation to thrombosis and coronary artery disease.
Topics: Coronary Artery Disease; Diet Therapy; Female; Genetic Testing; Homocysteine; Homocystinuria; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Pregnancy; Pregnancy Complications, Hematologic; Thrombosis | 2005 |
Maternal total homocysteine concentration and neonatal size in India.
Topics: Adult; Birth Weight; Erythrocytes; Female; Folic Acid; Gestational Age; Homocysteine; Humans; India; Infant, Newborn; Infant, Small for Gestational Age; Male; Maternal Nutritional Physiological Phenomena; Population Surveillance; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy.
Topics: Adult; Africa, Western; Betaine; Black People; Choline; Dietary Supplements; Female; Folic Acid; Gestational Age; Hematinics; Homocysteine; Humans; Netherlands Antilles; Nutritional Status; Postpartum Period; Predictive Value of Tests; Pregnancy; Regression Analysis | 2005 |
Elevated plasma homocysteine concentrations in severe preeclampsia and eclampsia.
Topics: Adult; Body Mass Index; Case-Control Studies; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eclampsia; Female; Homocysteine; Humans; Placenta; Pre-Eclampsia; Pregnancy; Regression Analysis; Uric Acid | 2005 |
Influence of combined methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase enhancer region (TSER) polymorphisms to plasma homocysteine levels in Korean patients with recurrent spontaneous abortion.
Topics: Abortion, Habitual; Adult; Enhancer Elements, Genetic; Female; Gene Frequency; Homocysteine; Humans; Korea; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Pregnancy; Retrospective Studies; Thymidylate Synthase | 2006 |
[Plasma homocysteine concentration and its relationship with the development of preeclampsia. Effect of prenatal administration of folic acid].
Topics: Adolescent; Adult; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Poverty; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimesters; Socioeconomic Factors | 2005 |
Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice.
Topics: Animals; Diet; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Heart Defects, Congenital; Homocysteine; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Pregnancy | 2005 |
Maternal plasma homocysteine concentrations are not increased in twin pregnancies.
Topics: Adult; Analysis of Variance; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Parity; Pregnancy; Pregnancy Outcome; Pregnancy, Multiple; Prenatal Care; Probability; Reference Values; Sensitivity and Specificity; Twins | 2005 |
Folate status of mothers during pregnancy and mental and psychomotor development of their children at five years of age.
Topics: Adult; Child Development; Child, Preschool; Cognition; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Intelligence; Memory; Poverty; Pregnancy; Prenatal Care; Psychomotor Performance; Vitamin B Complex; Zinc | 2005 |
Congenital heart defects and maternal biomarkers of oxidative stress.
Topics: Adult; Arkansas; Biomarkers; Case-Control Studies; Dipeptides; Female; Folic Acid; Glutathione; Glutathione Disulfide; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Life Style; Oxidative Stress; Pregnancy; Pregnancy Complications; Registries; Risk Factors; S-Adenosylhomocysteine; Vitamin B 6 | 2005 |
Hepatic S-adenosylmethionine after maternal alcohol exposure on offspring rats.
Topics: Animals; Animals, Newborn; Cysteine; DNA Methylation; Drug Administration Schedule; Ethanol; Female; Homocysteine; Lactation; Liver; Male; Maternal Behavior; Nutritional Status; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Wistar; S-Adenosylmethionine | 2005 |
Concentrations of homocysteine, related metabolites and asymmetric dimethylarginine in preeclamptic women with poor nutritional status.
Topics: Adult; Arginine; Female; Homocysteine; Humans; Nutritional Status; Pre-Eclampsia; Pregnancy; Time Factors; Vitamins | 2005 |
Choline, homocysteine, and pregnancy.
Topics: Animals; Choline; Choline Deficiency; Female; Homocysteine; Humans; Lactation; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Pregnancy | 2005 |
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12 | 2005 |
In pregnant women who smoke, caffeine consumption is associated with an increased level of homocysteine.
Topics: Caffeine; Central Nervous System Stimulants; Coffee; Female; Homocysteine; Humans; Pregnancy; Prospective Studies; Smoking; Tea; Vitamin B 12 | 2005 |
Folate, vitamin B12, and homocysteine levels in South Asian women with growth-retarded fetuses.
Topics: Adult; Age Factors; Birth Weight; Cohort Studies; Female; Fetal Blood; Fetal Development; Fetal Growth Retardation; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Luminescent Measurements; Pakistan; Pregnancy; Pregnancy Outcome; Prospective Studies; Social Class; Ultrasonography, Prenatal; Vitamin B 12 | 2005 |
Elevated homocysteine as a risk factor for the development of diabetes in women with a previous history of gestational diabetes mellitus: a 4-year prospective study.
Topics: Anthropometry; Blood Glucose; Blood Pressure; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Diabetes Mellitus; Diabetes, Gestational; Fasting; Female; Follow-Up Studies; Glucose Tolerance Test; Homocysteine; Hospitals, University; Humans; Insulin; Interviews as Topic; Korea; Postpartum Period; Pregnancy; Pregnancy Trimester, Second; Prevalence; Prospective Studies; Risk Factors; Time Factors; Triglycerides | 2005 |
[Folate and homocysteine levels during pregnancy affect DNA methylation in human placenta].
Topics: Adult; DNA Methylation; Embryonic Development; Female; Folic Acid; Homocysteine; Humans; Immunohistochemistry; Methylenetetrahydrofolate Reductase (NADPH2); Placenta; Polymorphism, Restriction Fragment Length; Pregnancy; Pregnancy Trimester, Second | 2005 |
Combining 2nd-trimester maternal serum homocysteine levels and uterine artery Doppler for prediction of preeclampsia and isolated intrauterine growth restriction.
Topics: Abruptio Placentae; Adult; Arteries; Biomarkers; Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Mass Screening; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Second; Prospective Studies; Sensitivity and Specificity; Stillbirth; Ultrasonography, Doppler; Uterus | 2006 |
Congenital heart defects, maternal homocysteine, smoking, and the 677 C>T polymorphism in the methylenetetrahydrofolate reductase gene: evaluating gene-environment interactions.
Topics: Adult; Case-Control Studies; Cytosine; Female; Genetic Predisposition to Disease; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Smoking; Thymine | 2006 |
Impact of methylenetetrahydrofolate reductase deficiency and low dietary folate on the development of neural tube defects in splotch mice.
Topics: Animals; Female; Folic Acid Deficiency; Gestational Age; Heterozygote; Homocysteine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Mutant Strains; Neural Tube Defects; Paired Box Transcription Factors; PAX3 Transcription Factor; Pregnancy | 2006 |
Erythrocyte folate, plasma folate and plasma homocysteine during normal pregnancy and postpartum: a longitudinal study comprising 404 Danish women.
Topics: Adult; Denmark; Erythrocytes; Female; Folic Acid; Gestational Age; Guideline Adherence; Homocysteine; Humans; Lactation; Longitudinal Studies; Postpartum Period; Pregnancy | 2006 |
Early onset of subclinical atherosclerosis in women with gestational diabetes mellitus.
Topics: Adult; Atherosclerosis; Blood Glucose; Carotid Artery Diseases; Case-Control Studies; Cholesterol; Diabetes, Gestational; Female; Homocysteine; Humans; Pregnancy; Prospective Studies; Tunica Intima | 2006 |
The maternal combined supplementation of folic acid and Vitamin B(12) suppresses ethanol-induced developmental toxicity in mouse fetuses.
Topics: Abnormalities, Drug-Induced; Alcoholic Intoxication; Animals; Bone and Bones; Dietary Supplements; Embryo Implantation; Embryo Loss; Ethanol; Female; Fetal Development; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Mice; Pregnancy; Vitamin B 12 | 2006 |
Plasma homocysteine in late pregnancies complicated with preeclampsia and in newborns.
Topics: Adult; Female; Homocysteine; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Prospective Studies | 2006 |
Maternal homocysteine and congenital heart defects.
Topics: Adult; Biomarkers; Female; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Pregnancy; Prenatal Diagnosis | 2006 |
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; Citrates; Cystathionine; False Negative Reactions; Female; Gastric Bypass; Heterozygote; Homocysteine; Humans; Hydroxocobalamin; Infant Food; Infant, Newborn; Malabsorption Syndromes; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency | 2005 |
Elevated soluble vascular cell adhesion molecule-1, elevated Homocyst(e)inemia, and hypertriglyceridemia in relation to preeclampsia risk.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hypertriglyceridemia; Odds Ratio; Pre-Eclampsia; Pregnancy; Risk Factors; Triglycerides; Vascular Cell Adhesion Molecule-1 | 2006 |
Relation of parity and homocysteine to bone mineral density of postmenopausal women.
Topics: Absorptiometry, Photon; Amino Acids; Blood Chemical Analysis; Bone Density; Developing Countries; Female; Homocysteine; Humans; Lumbosacral Region; Middle Aged; Osteoporosis; Parity; Postmenopause; Pregnancy; Turkey | 2006 |
Post-interventional homocysteine levels: failure as a predictive biomarker of in-stent restenosis.
Topics: Angioplasty, Balloon, Coronary; Biomarkers; Coronary Angiography; Coronary Disease; Coronary Restenosis; Female; Homocysteine; Humans; Male; Middle Aged; Postoperative Care; Predictive Value of Tests; Pregnancy; Statistics, Nonparametric; Stents | 2006 |
Maternal folate receptor autoantibodies and cleft lip and/or palate.
Topics: Adult; Autoantibodies; Carrier Proteins; Case-Control Studies; Cleft Lip; Cleft Palate; Female; Folate Receptors, GPI-Anchored; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Receptors, Cell Surface | 2006 |
Cobalamin status during normal pregnancy and postpartum: a longitudinal study comprising 406 Danish women.
Topics: Adult; Cohort Studies; Denmark; Female; Follow-Up Studies; Hemoglobins; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Postpartum Period; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, Third; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Homocysteine levels in amniotic fluid. Relationship with birth-weight.
Topics: Adult; Amniotic Fluid; Birth Weight; Chromosome Aberrations; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Infant, Small for Gestational Age; Male; Pregnancy; Pregnancy Outcome; Prenatal Diagnosis; Twins | 2006 |
Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study.
Topics: Adult; Factor V; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Maternal Age; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Norway; Odds Ratio; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies; Risk Factors; Smoking; Vitamin B 12 | 2006 |
The MTHFR 1298CC and 677TT genotypes have opposite associations with red cell folate levels.
Topics: Biomarkers; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Prospective Studies | 2006 |
Antiepileptic drugs: a case report in a pregnancy with a neural tube defect.
Topics: Adult; Anticonvulsants; Female; Folic Acid; Homocysteine; Humans; Lamotrigine; Myoclonic Epilepsy, Juvenile; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy, Multiple; Triazines; Triplets; Vitamin B Complex | 2006 |
Effect of maternal exposure to homocystine on sodium valproate-induced neural tube defects in the mouse embryos.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Homocystine; Mice; Neural Tube Defects; Pregnancy; Random Allocation; Teratogens; Valproic Acid; Vitamin B 12 | 2006 |
Increased intima-media thickness after early-onset preeclampsia.
Topics: Adult; Carotid Artery Diseases; Carotid Artery, Common; Carotid Artery, Internal; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, First; Pregnancy Trimester, Second; Triglycerides; Tunica Intima; Tunica Media | 2006 |
Elevated second trimester serum homocysteine levels in women with gestational diabetes mellitus.
Topics: Adult; Body Mass Index; Cross-Sectional Studies; Diabetes, Gestational; Female; Folic Acid; Gestational Age; Glucose Intolerance; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, Second; Reference Values; Vitamin B 12 | 2006 |
C-reactive protein and metabolic syndrome in women with previous gestational diabetes.
Topics: Abdomen; Adult; C-Reactive Protein; Diabetes, Gestational; Female; Fibrinogen; Homocysteine; Humans; Hyperglycemia; Lipoproteins, HDL; Metabolic Syndrome; Obesity; Parity; Pregnancy; Reference Values; Triglycerides | 2007 |
Plasma homocysteine, folate and vitamin B(12) compared between rural Gambian and UK adults.
Topics: Adult; Age Distribution; Black People; Female; Folic Acid; Gambia; Homocysteine; Humans; Lactation; Male; Middle Aged; Pregnancy; Rural Health; Sex Distribution; United Kingdom; Vitamin B 12; White People | 2006 |
Maternal protein restriction and fetal growth: lack of evidence of a role for homocysteine in fetal programming.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Antioxidants; Catalase; Diet, Protein-Restricted; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Fetal Blood; Fetal Development; Fetal Weight; Glutathione Peroxidase; Homocysteine; Liver; Male; Maternal-Fetal Exchange; Organ Size; Oxidation-Reduction; Placenta; Pregnancy; Pregnancy Proteins; Rats; RNA, Messenger; Superoxide Dismutase | 2006 |
Homocysteine, folic acid and B12 serum levels in pregnancy complicated with preeclampsia.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Vitamin B 12 | 2007 |
[Hyperhomocystinemia as a thrombotic risk factor in patients suffering from systemic lupus erithematosus and antiphospholipid syndrome].
Topics: Adult; Aged; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Argentina; Biomarkers; Case-Control Studies; Chi-Square Distribution; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lupus Erythematosus, Systemic; Male; Middle Aged; Pregnancy; Risk Factors; Thrombosis | 2005 |
Folate, vitamin B12 and total homocysteine levels in neonates from Brazil.
Topics: Adult; Cross-Sectional Studies; Dietary Supplements; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Nutritional Status; Pregnancy; Prenatal Care; Social Class; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex | 2007 |
Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation.
Topics: Blood Coagulation; Blood Pressure; Case-Control Studies; Cell Communication; Female; Genotype; Homocysteine; Humans; Infant, Newborn; Inflammation; Limb Deformities, Congenital; Male; Maternal-Fetal Exchange; Odds Ratio; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Smoking; Vitamins | 2006 |
Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss.
Topics: Abortion, Habitual; Adolescent; Adult; Aged; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Thrombosis; Vitamin B 12 | 2007 |
Newborns of pre-eclamptic women: a biochemical difference present in utero.
Topics: Abdomen; Adult; Anthropometry; Biomarkers; Birth Weight; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Fetal Blood; Fibrinogen; Gestational Age; Homocysteine; Humans; Infant, Newborn; Lipids; Pre-Eclampsia; Pregnancy; Triglycerides | 2006 |
Maternal hyperhomocysteinaemia is a risk factor for congenital heart disease.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Maternal Age; Pregnancy; Pregnancy Complications; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 2006 |
Plasma vitamin values and antiepileptic therapy: case reports of pregnancy outcomes affected by a neural tube defect.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Valproic Acid; Vitamin B 12; Vitamin B 6 | 2007 |
Dietary intake of B-vitamins in mothers born a child with a congenital heart defect.
Topics: Adult; Case-Control Studies; Dietary Proteins; Educational Status; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Logistic Models; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Nutritional Status; Pregnancy; Pregnancy Complications; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2006 |
Effect of diet composition on pregnancy outcome in overnourished rapidly growing adolescent sheep.
Topics: Animals; Animals, Newborn; Birth Weight; Colostrum; Dietary Proteins; Energy Metabolism; Female; Fetal Development; Homocysteine; Immunoglobulin G; Insulin; Mammary Glands, Animal; Maternal Nutritional Physiological Phenomena; Models, Animal; Nutritional Status; Overnutrition; Placentation; Pregnancy; Pregnancy Outcome; Pregnancy, Animal; Sheep, Domestic | 2006 |
Elevated prenatal homocysteine levels as a risk factor for schizophrenia.
Topics: Adult; Case-Control Studies; Child; Child of Impaired Parents; Cohort Studies; Female; Homocysteine; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, Third; Prenatal Exposure Delayed Effects; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Risk Factors; Schizophrenia | 2007 |
Gestational vitamin B deficiency leads to homocysteine-associated brain apoptosis and alters neurobehavioral development in rats.
Topics: Animals; Apoptosis; Astrocytes; Behavior, Animal; Brain; Female; Homocysteine; Hyperhomocysteinemia; Maze Learning; Memory; Neurons; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Time Factors; Tumor Suppressor Protein p53; Vitamin B Deficiency | 2007 |
Maternal vitamin B12 and the risk of fetal neural tube defects in Egyptian patients.
Topics: Case-Control Studies; Egypt; Female; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Neural Tube Defects; Odds Ratio; Pregnancy; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Plasma cysteine concentrations in uncomplicated pregnancies.
Topics: Adolescent; Adult; Biomarkers; Blood Pressure; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Prospective Studies | 2007 |
Polymorphisms in methionine synthase reductase and betaine-homocysteine S-methyltransferase genes: risk of placental abruption.
Topics: Abruptio Placentae; Adolescent; Adult; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Polymorphism, Genetic; Pregnancy; Risk Factors; Vitamin B 12 | 2007 |
Heterodimeric amino acid transporters in the placenta--a workshop report.
Topics: Amino Acid Transport Systems; Animals; Dimerization; Female; Homocysteine; Humans; Leucine; Placenta; Pregnancy | 2007 |
Circulating endothelial cells in preeclampsia.
Topics: Adult; Biomarkers; Case-Control Studies; Endothelial Cells; Endothelium, Vascular; Female; Homocysteine; Humans; Hypertension; Pre-Eclampsia; Pregnancy | 2007 |
Preconception B-vitamin and homocysteine status, conception, and early pregnancy loss.
Topics: Abortion, Spontaneous; Adult; China; Chorionic Gonadotropin; Female; Fertilization; Folic Acid; Homocysteine; Humans; Odds Ratio; Preconception Care; Pregnancy; Prospective Studies; Risk Assessment; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
Effects of gestational and lactational choline deprivation on brain antioxidant status, acetylcholinesterase, (Na(+),K(+))- and Mg(2+)-ATPase activities in offspring rats.
Topics: Acetylcholinesterase; Animals; Animals, Newborn; Antioxidants; Brain; Ca(2+) Mg(2+)-ATPase; Choline Deficiency; Female; Homocysteine; Hydrolases; Lactation; Male; Pregnancy; Rats; Sodium-Potassium-Exchanging ATPase | 2007 |
Folate status in women of childbearing age with epilepsy.
Topics: Adolescent; Adult; Chi-Square Distribution; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Pregnancy; Surveys and Questionnaires | 2007 |
Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alleles; Analysis of Variance; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Young Adult | 2008 |
Secondary palatal closure in rats in association with relative maternofetal levels of folic acid, vitamin B12, and homocysteine.
Topics: Animals; Embryonic Development; Female; Folic Acid; Homocysteine; Maternal-Fetal Exchange; Palate; Pregnancy; Rats; Rats, Inbred Lew; Vitamin B 12 | 2007 |
[Homocysteine decreases the invasion in cultured human trophoblasts: relationship between homocysteine and matrix metalloproteinase-2, -9 expression].
Topics: Adult; Cells, Cultured; Female; Gestational Age; Homocysteine; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trophoblasts | 2007 |
Red cell folate and plasma homocysteine in preterm infants.
Topics: Brain Diseases; Dietary Supplements; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Infant Formula; Infant, Newborn; Infant, Premature; Male; Milk, Human; Pregnancy | 2007 |
Reference intervals for haematological variables during normal pregnancy and postpartum in 434 healthy Danish women.
Topics: Creatinine; Denmark; Female; Ferritins; Folic Acid; Hematologic Tests; Homocysteine; Humans; Methylmalonic Acid; Postpartum Period; Pregnancy; Receptors, Transferrin; Reference Values; Vitamin B 12 | 2007 |
Homocysteine, cysteine, and related metabolites in maternal and fetal plasma in preeclampsia.
Topics: Adult; Birth Weight; Cysteine; Female; Fetal Blood; Fetus; Homocysteine; Humans; Infant; Pre-Eclampsia; Pregnancy; Statistics as Topic | 2007 |
Relationship between dietary folate intakes, maternal plasma total homocysteine and B-vitamins during pregnancy and fetal growth in Japan.
Topics: Adult; Biomarkers; Birth Weight; Body Mass Index; Erythrocytes; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Infant, Newborn; Japan; Male; Nutritional Status; Parity; Pregnancy; Pregnancy Outcome; Vitamin B 12; Vitamin B Complex | 2007 |
Lipofuscin, homocysteine and tissue polypeptide specific antigen in gestational hypertension.
Topics: Blood Pressure; Creatinine; Female; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Lipofuscin; Oxidative Stress; Peptides; Pregnancy | 2007 |
[Study of animal model of hypertensive disorder complicating pregnancy in pregnant rats stimulated by homocysteine and monosodium glutamate].
Topics: Animals; Animals, Newborn; Blood Pressure; Cerebral Cortex; Disease Models, Animal; Female; Homocysteine; Hypertension, Pregnancy-Induced; Kidney; Liver Function Tests; Male; Pregnancy; Random Allocation; Rats; Rats, Wistar; Sodium Glutamate | 2007 |
Elevated prenatal homocysteine levels and the risk of schizophrenia.
Topics: DNA Methylation; Epigenesis, Genetic; Female; Homocysteine; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Promoter Regions, Genetic; Schizophrenia | 2007 |
Plasma homocysteine levels in cycling, pregnant, and spayed bitches.
Topics: Animals; Dogs; Estrous Cycle; Female; Homocysteine; Hysterectomy; Ovariectomy; Pregnancy | 2008 |
Effects of concentrations of cyanocobalamin in the gestation diet on some criteria of vitamin B12 metabolism in first-parity sows.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Colostrum; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Lactation; Parity; Pregnancy; Pregnancy, Animal; Random Allocation; Swine; Vitamin B 12 | 2007 |
Influence of preconditioning-like hypoxia on the liver of developing methyl-deficient rats.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Choline Deficiency; Cystathionine beta-Synthase; Female; Folic Acid; Folic Acid Deficiency; Food, Formulated; Glutathione; Homocysteine; Hypoxia; Liver; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Wistar; Riboflavin; Riboflavin Deficiency; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Deficiency | 2007 |
Homocysteine is toxic for dopaminergic neurons in primary mesencephalic culture.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antipsychotic Agents; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Embryo, Mammalian; Female; Homocysteine; Mesencephalon; Microtubule-Associated Proteins; Neurons; Neurotoxins; Pregnancy; Rats; Rats, Sprague-Dawley; Reserpine; Tyrosine 3-Monooxygenase | 2007 |
The transient increase of oxidative stress during normal pregnancy is higher and persists after delivery in women with pre-eclampsia.
Topics: Adult; Case-Control Studies; Female; Glutathione; Homocysteine; Humans; Oxidative Stress; Pre-Eclampsia; Pregnancy | 2008 |
Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study.
Topics: Adipose Tissue; Anthropometry; Body Composition; Body Mass Index; Child; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Male; Methylmalonic Acid; Pregnancy; Pregnancy Complications; Vitamin B 12 | 2008 |
Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption.
Topics: Abruptio Placentae; Adolescent; Adult; Alleles; Case-Control Studies; DNA; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Linkage Disequilibrium; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pregnancy; Social Class; Vitamin B 12 | 2007 |
[The relationship between polymorphism of gene involved in folate metabolism, homocysteine level and risk of Down syndrome].
Topics: Adult; Alleles; Base Sequence; Case-Control Studies; Down Syndrome; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Pregnancy | 2007 |
Determinants of arsenic metabolism: blood arsenic metabolites, plasma folate, cobalamin, and homocysteine concentrations in maternal-newborn pairs.
Topics: Adult; Arsenic; Arsenic Poisoning; Bangladesh; Biomarkers; Cohort Studies; Environmental Exposure; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Vitamin B 12; Water Supply | 2007 |
Effect of homocysteine concentration in early pregnancy on gestational hypertensive disorders and other pregnancy outcomes.
Topics: Abortion, Spontaneous; Female; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Infant, Small for Gestational Age; Pre-Eclampsia; Pregnancy; Risk Factors | 2008 |
Lack of consistent association between endothelial nitric oxide synthase gene polymorphisms, homocysteine levels and recurrent pregnancy loss in tunisian women.
Topics: Abortion, Habitual; Adult; Case-Control Studies; DNA; Female; Genotype; Homocysteine; Humans; Linkage Disequilibrium; Minisatellite Repeats; Nitric Oxide Synthase Type III; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Statistics, Nonparametric; Tunisia | 2008 |
Total plasma homocysteine correlates in women with gestational diabetes.
Topics: Adult; Case-Control Studies; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Pregnancy; Vitamin B 12 | 2008 |
Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study.
Topics: Adult; Betaine; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methionine; Parturition; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Third; Seychelles; Vitamin B 12; Vitamin B Complex | 2008 |
Prenatal diagnosis of methylmalonic aciduria by analysis of organic acids and total homocysteine in amniotic fluid.
Topics: Amniotic Fluid; Carnitine; Citrates; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methylmalonic Acid; Pregnancy; Prenatal Diagnosis; Spectrometry, Mass, Electrospray Ionization | 2008 |
Plasma homocysteine, vitamin B12 and folate levels in hydatidiform moles and histopathological subtypes.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hydatidiform Mole; Pregnancy; Statistics, Nonparametric; Uterine Neoplasms; Vitamin B 12 | 2008 |
Nutritional and genetic determinants of vitamin B and homocysteine metabolisms in neural tube defects: a multicenter case-control study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Case-Control Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; France; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Nutritional Status; Polymorphism, Genetic; Pregnancy; Prospective Studies; Risk Factors; Vitamin B Complex | 2008 |
[Serum folate and homocysteine concentrations in women smoking during pregnancy and in umbilical cord blood of newborns].
Topics: Adult; Birth Weight; Female; Fetal Blood; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Low Birth Weight; Infant, Newborn; Pregnancy; Smoking | 2007 |
Polymorphisms in genes related to folate and cobalamin metabolism and the associations with complex birth defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amniotic Fluid; Case-Control Studies; Child; Congenital Abnormalities; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Risk Factors; Transcobalamins; Vitamin B 12 | 2008 |
Abnormal folate metabolism as a risk factor for first-trimester spontaneous abortion.
Topics: Abortion, Spontaneous; Adolescent; Adult; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Gestational Age; Homocysteine; Humans; Pilot Projects; Pregnancy; Pregnancy Trimester, First; Risk Factors | 2008 |
Anesthetic management of a parturient with hyperhomocysteinemia.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Inhalation; Anticoagulants; Blood Coagulation; Blood Coagulation Tests; Blood Loss, Surgical; Cesarean Section; Drug Administration Schedule; Enoxaparin; Female; Heparin; Homocysteine; Humans; Hyperhomocysteinemia; Live Birth; Nitrous Oxide; Parturition; Pregnancy; Pregnancy Complications, Hematologic | 2008 |
Possible mechanism of action of 2-hydroxylated estradiol on the positive feedback control for LH release in the rat.
Topics: alpha-Methyltyrosine; Animals; Castration; Catechol O-Methyltransferase; Estradiol; Estrogens, Catechol; Feedback; Female; Homocysteine; Hypothalamus; Luteinizing Hormone; Methyltyrosines; Pregnancy; Proestrus; Rats; Tyrosine 3-Monooxygenase | 1983 |
Homocysteinemia, ischemic heart disease, and the carrier state for homocystinuria.
Topics: Adult; Amino Acids, Sulfur; Aminobutyrates; Coronary Disease; Diseases in Twins; Female; Heterozygote; Homocysteine; Homocystinuria; Humans; Male; Methionine; Middle Aged; Myocardial Infarction; Pregnancy; Twins, Monozygotic | 1983 |
Methionine regulation of N-5-methyltetrahydrofolate: homocysteine methyltransferase and its influence on the growth and protein synthesis in normal, neoplastic, and transformed cells in culture.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cricetulus; Enzyme Induction; Female; Fibroblasts; HeLa Cells; Homocysteine; Homocysteine S-Methyltransferase; Humans; Methionine; Methyltransferases; Pregnancy; Protein Biosynthesis; Rats | 1982 |
Dietary methionine does not reduce penetrance in curly tail mice but causes a phenotype-specific decrease in embryonic growth.
Topics: Animals; Diet; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Homocysteine; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Mutant Strains; Neural Tube Defects; Phenotype; Pregnancy; Weight Gain | 1995 |
Underlying disorders associated with severe early-onset preeclampsia.
Topics: Antibodies, Anticardiolipin; Antithrombin III Deficiency; Female; Homocysteine; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Protein C; Protein S Deficiency; Thrombosis | 1995 |
Spontaneous hair hyperpigmentation in response to vitamin intake in pregnancy--a clue for homocystinuria.
Topics: Adult; Cystathionine beta-Synthase; Cysteine; Female; Fibroblasts; Hair Color; Hair Diseases; Homocysteine; Homocystinuria; Humans; Hyperpigmentation; Pregnancy; Skin; Vitamins | 1995 |
Development of methionine synthase, cystathionine-beta-synthase and S-adenosyl-homocysteine hydrolase during gestation in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Cystathionine beta-Synthase; Decidua; Female; Folic Acid; Homocysteine; Hydrolases; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar | 1995 |
Prevention of neural tube defects by and toxicity of L-homocysteine in cultured postimplantation rat embryos.
Topics: Adenosylhomocysteinase; Animals; Catalase; Copper; Copper Sulfate; Culture Techniques; Drug Interactions; Embryonic and Fetal Development; Embryonic Development; Female; Homocysteine; Homocystine; Hydrolases; Methionine; Neural Tube Defects; Oxidation-Reduction; Pregnancy; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism; Teratogens; Vitamin B 12 | 1994 |
Biochemical indices of vitamin B12 nutrition in pregnant patients with subnormal serum vitamin B12 levels.
Topics: Female; Homocysteine; Humans; Methylmalonic Acid; Nutritional Status; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency | 1995 |
Homocysteine metabolism in pregnancies complicated by neural-tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Analysis of Variance; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylation; Methylmalonic Acid; Neural Tube Defects; Pregnancy; Vitamin B 12 | 1995 |
Methylation in fertilised and parthenogenetic preimplantation mouse embryos.
Topics: Animals; DNA Modification Methylases; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Genomic Imprinting; Homocysteine; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Parthenogenesis; Pregnancy; S-Adenosylmethionine | 1994 |
Maternal hyperhomocysteinemia: a risk factor for neural-tube defects?
Topics: Adult; Anencephaly; Cystathionine beta-Synthase; Encephalocele; Female; Folic Acid; Homocysteine; Humans; Meningomyelocele; Methionine; Neural Tube Defects; Pregnancy; Pregnancy Complications; Risk Factors | 1994 |
The methylfolate axis in neural tube defects: in vitro characterisation and clinical investigation.
Topics: Animals; Anticonvulsants; Female; Folic Acid; Homocysteine; Humans; In Vitro Techniques; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Rats; Rats, Wistar; Tetrahydrofolates | 1994 |
Primary prevention of neural-tube defects with folic acid.
Topics: Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Nutritional Physiological Phenomena; Pregnancy; Primary Prevention | 1994 |
Hyperhomocysteinemia: a risk factor in women with unexplained recurrent early pregnancy loss.
Topics: Abortion, Habitual; Adult; Amino Acid Metabolism, Inborn Errors; Case-Control Studies; Female; Homocysteine; Humans; Methionine; Middle Aged; Pregnancy; Pregnancy Trimester, First; Prevalence; Risk Factors | 1993 |
In vitro and in vivo inactivation of transcobalamin II receptor by its antiserum.
Topics: Animals; Antibodies; Cell Line; Cell Membrane; Cobalt Radioisotopes; Female; Homocysteine; Humans; Intestinal Mucosa; Kidney; Kinetics; Liver; Macromolecular Substances; Methylmalonic Acid; Placenta; Pregnancy; Rabbits; Radioligand Assay; Receptors, Cell Surface; Reference Values; Staphylococcal Protein A; Transcobalamins; Tumor Cells, Cultured | 1996 |
Hyperhomocysteinemia: a risk factor for placental abruption or infarction.
Topics: Abortion, Habitual; Abruptio Placentae; Adult; Case-Control Studies; Female; Homocysteine; Humans; Infarction; Placenta; Pregnancy; Prevalence; Risk Factors | 1996 |
Maternal and fetal levels of methionine and homocysteine in early human pregnancy.
Topics: Amniotic Fluid; Cross-Sectional Studies; Female; Fetus; Gestational Age; Homocysteine; Humans; Methionine; Pregnancy; Pregnancy Trimester, First | 1997 |
Coffee consumption and plasma total homocysteine: The Hordaland Homocysteine Study.
Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol; Coffee; Cohort Studies; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Male; Middle Aged; Norway; Pregnancy; Pregnancy Outcome; Risk Factors; Surveys and Questionnaires | 1997 |
Are common mutations of cystathionine beta-synthase involved in the aetiology of neural tube defects?
Topics: Cystathionine beta-Synthase; DNA Transposable Elements; Female; Gene Frequency; Haplotypes; Heterozygote; Homocysteine; Homozygote; Humans; Infant, Newborn; Ireland; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Pregnancy; Risk Factors; Sequence Analysis, DNA | 1997 |
Elevated homocyst(e)ine levels with preeclampsia.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Parity; Pre-Eclampsia; Pregnancy; Risk Factors; Vascular Diseases; Vitamin B 12 | 1997 |
Genetic risk factor for unexplained recurrent early pregnancy loss.
Topics: Abortion, Habitual; Case-Control Studies; Female; Homocysteine; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Risk Factors | 1997 |
Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinaemia in neural-tube defects and vascular disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Arterial Occlusive Diseases; Female; Genotype; Homocysteine; Humans; Male; Molecular Sequence Data; Mutation; Neural Tube Defects; Odds Ratio; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Cardiovascular; Sequence Analysis, DNA | 1997 |
[Megaloblastic anemia: rapid and economical study].
Topics: Adolescent; Adult; Algorithms; Anemia, Megaloblastic; Cost Control; Diagnosis, Differential; Diagnostic Tests, Routine; Female; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Histidine; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Hematologic; Reticulocyte Count; Retrospective Studies; Sensitivity and Specificity; Time Factors; Urinalysis; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Hyperhomocysteinaemia and protein S deficiency in complicated pregnancies.
Topics: Abruptio Placentae; Antibodies, Anticardiolipin; Blood Coagulation Disorders; Female; Fetal Death; Gestational Age; Homocysteine; Humans; Infant, Small for Gestational Age; Pregnancy; Pregnancy Complications, Hematologic; Protein S Deficiency; Risk Factors | 1997 |
A woman with five consecutive fetal deaths: case report and retrospective analysis of hyperhomocysteinemia prevalence in 100 consecutive women with recurrent miscarriages.
Topics: Abortion, Habitual; Adult; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Osmolar Concentration; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Pregnancy Outcome; Pyridoxine; Reference Values; Retrospective Studies | 1998 |
The relationship between maternal and neonatal umbilical cord plasma homocyst(e)ine suggests a potential role for maternal homocyst(e)ine in fetal metabolism.
Topics: Adult; Female; Fetal Blood; Folic Acid; Homocysteine; Homocystine; Humans; Infant, Newborn; Labor, Obstetric; Maternal-Fetal Exchange; Pregnancy; Reference Values; Umbilical Arteries; Umbilical Veins | 1998 |
Tissue plasminogen activator binding to the annexin II tail domain. Direct modulation by homocysteine.
Topics: Amino Acid Sequence; Annexin A2; Binding Sites; Cell Line; Cell Membrane; Female; Homocysteine; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Placenta; Point Mutation; Pregnancy; Recombinant Proteins; Spectrometry, Mass, Secondary Ion; Tissue Plasminogen Activator; Transfection | 1998 |
Strategies for the treatment of cystathionine beta-synthase deficiency: the experience of the Willink Biochemical Genetics Unit over the past 30 years.
Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Female; Folic Acid; Gastrointestinal Agents; Genetic Testing; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Pregnancy; Pregnancy Complications; Pyridoxine; Treatment Failure; Treatment Outcome | 1998 |
Neural-tube defects are associated with low concentrations of cobalamin (vitamin B12) in amniotic fluid.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amniocentesis; Amniotic Fluid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Neural Tube Defects; Pilot Projects; Pregnancy; Reference Values; Vitamin B 12 | 1998 |
Methylenetetrahydrofolate reductase polymorphism affects the change in homocysteine and folate concentrations resulting from low dose folic acid supplementation in women with unexplained recurrent miscarriages.
Topics: Abortion, Habitual; Adult; Dietary Supplements; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pregnancy | 1998 |
VPA-induced neural tube defects in mice. I. Altered metabolism of sulfur amino acids and glutathione.
Topics: Abnormalities, Drug-Induced; Amino Acids; Animals; Anticonvulsants; Female; Folic Acid; Glutathione; Homocysteine; Liver; Methionine; Mice; Neural Tube Defects; Pregnancy; Valproic Acid | 1998 |
Reliability of biochemical parameters used in prenatal diagnosis of combined methylmalonic aciduria and homocystinuria.
Topics: Amino Acid Metabolism, Inborn Errors; Amniocentesis; Amniotic Fluid; Cells, Cultured; Chorion; Chorionic Villi Sampling; Cobamides; Female; Gestational Age; Homocysteine; Homocystinuria; Humans; Male; Methylmalonic Acid; Pregnancy; Propionates; Tetrahydrofolates; Vitamin B 12 | 1998 |
[A correlation study on homocysteine metabolism in pregnant women and neural tube defects in urban and rural areas].
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Random Allocation; Rural Health; Urban Health; Vitamin B 12 | 1997 |
Absorption of dietary and supplemental folate in women with prior pregnancies with neural tube defects and controls.
Topics: Absorption; Adult; Biological Availability; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pteroylpolyglutamic Acids; Vitamin B 12; Zinc | 1998 |
Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation.
Topics: Adult; Endothelium, Vascular; Female; Fibronectins; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Risk Factors | 1998 |
Folate status, homocysteine metabolism, and methylene tetrahydrofolate reductase genotype in rural South African blacks with a history of pregnancy complicated by neural tube defects.
Topics: Adult; Black People; DNA; Female; Folic Acid; Genotype; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Neural Tube Defects; Nutritional Status; Pregnancy; Pregnancy Complications; Rural Population; South Africa | 1999 |
Changes in homocysteine levels during normal pregnancy.
Topics: Adult; Case-Control Studies; Cohort Studies; Confidence Intervals; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Pregnancy; Serum Albumin; Vitamin B 12 | 1999 |
Maternal plasma homocysteine, placenta status and docosahexaenoic acid concentration in erythrocyte phospholipids of the newborn.
Topics: Adult; Calcinosis; Docosahexaenoic Acids; Erythrocyte Membrane; Female; Homocysteine; Humans; Infant, Newborn; Phospholipids; Placenta; Placenta Diseases; Pregnancy; Pregnancy Complications | 1999 |
Plasma homocysteine levels elevated and inversely related to insulin sensitivity in preeclampsia.
Topics: Adult; Female; Homocysteine; Humans; Insulin Resistance; Pre-Eclampsia; Pregnancy | 1999 |
[Obstetric problems followed by stroke].
Topics: Abortion, Habitual; Adult; Arteriosclerosis; Cerebral Infarction; Diagnosis, Differential; Female; Fetal Death; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Male; Methionine; Nutrition Disorders; Placental Insufficiency; Pregnancy; Pregnancy Complications, Cardiovascular; Pyridoxine; Smoking; Venous Thrombosis; Vitamin B 6 Deficiency | 1999 |
Is pregnancy in diabetic women associated with folate deficiency?
Topics: Adult; Creatinine; Diet; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Glycated Hemoglobin; Homocysteine; Humans; Pregnancy; Pregnancy in Diabetics; Reference Values; Vitamin B 12 | 1999 |
Plasma homocyst(e)ine concentrations in eclamptic and preeclamptic African women postpartum.
Topics: Adolescent; Adult; Case-Control Studies; Eclampsia; Female; Homocysteine; Humans; Postpartum Period; Pregnancy; Risk Factors; Zimbabwe | 1999 |
Turn of tide for oral vitamin B12 treatment.
Topics: Administration, Oral; Aged; Biological Availability; Biomarkers; England; Female; Homocysteine; Humans; Infusions, Intravenous; Methylmalonic Acid; Neural Tube Defects; Pregnancy; Pregnancy Complications; Sweden; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Folate and homocysteine metabolism and gene polymorphisms in the etiology of Down syndrome.
Topics: Down Syndrome; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Nutritional Physiological Phenomena; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pregnancy | 1999 |
Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development.
Topics: Animals; Carrier Proteins; Cell Line; Embryonic and Fetal Development; Female; Fetal Death; Folate Receptor 1; Folate Receptors, GPI-Anchored; Folic Acid; Genotype; Homocysteine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nervous System; Pregnancy; Receptors, Cell Surface | 1999 |
Nonsyndromic orofacial clefts: association with maternal hyperhomocysteinemia.
Topics: Adult; Case-Control Studies; Child, Preschool; Cleft Lip; Cleft Palate; Erythrocytes; Fasting; Female; Folic Acid; Homocysteine; Humans; Infant; Maternal-Fetal Exchange; Methionine; Pregnancy; Pyridoxine; Risk Factors; Vitamin B 12 | 1999 |
Amniotic fluid homocysteine levels, 5,10-methylenetetrahydrafolate reductase genotypes, and neural tube closure sites.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alanine; Amino Acid Substitution; Amniotic Fluid; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Oxidoreductases; Point Mutation; Pregnancy; Valine | 2000 |
Role of amniotic fluid homocysteine level and of fetal 5, 10-methylenetetrahydrafolate reductase genotype in the etiology of neural tube defects.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alanine; Amino Acid Substitution; Amniotic Fluid; Female; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Oxidoreductases; Point Mutation; Pregnancy; Valine | 2000 |
Evaluation of low serum vitamin B(12) in the non-anaemic pregnant patient.
Topics: Adult; Erythrocyte Indices; Female; Gestational Age; Homocysteine; Humans; Methylmalonic Acid; Parity; Pregnancy; Pregnancy Complications; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Methylenetetrahydrofolate reductase 677 C --> T polymorphism, plasma folate, vitamin B(12) concentrations, and risk of preeclampsia among black African women from Zimbabwe.
Topics: Adolescent; Adult; Alleles; Black People; Case-Control Studies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nutritional Physiological Phenomena; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Risk Factors; Vitamin B 12; Zimbabwe | 2000 |
Plasma thiol status in preeclampsia.
Topics: Adult; Case-Control Studies; Cysteine; Female; Glutathione; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Sulfhydryl Compounds | 2000 |
Homocysteine and folate levels as risk factors for recurrent early pregnancy loss.
Topics: Abortion, Habitual; Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Odds Ratio; Pregnancy; Risk | 2000 |
Is homocysteine a biomarker for identifying women at risk of complications and adverse pregnancy outcomes?
Topics: Biomarkers; Female; Homocysteine; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Risk Factors | 2000 |
Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine study.
Topics: Abruptio Placentae; Adult; Aged; Biomarkers; Clubfoot; Congenital Abnormalities; Female; Fetal Death; Fetal Growth Retardation; Folic Acid Deficiency; Homocysteine; Humans; Infant, Newborn; Infant, Very Low Birth Weight; Male; Middle Aged; Neural Tube Defects; Norway; Obstetric Labor, Premature; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Registries; Risk Factors | 2000 |
Maternal homocysteine and chorionic vascularization in recurrent early pregnancy loss.
Topics: Abortion, Habitual; Adult; Blood Vessels; Chorion; Female; Gestational Age; Homocysteine; Humans; Methionine; Pregnancy | 2000 |
Re: Pregnancy outcomes in celiac women.
Topics: Autoantibodies; Birth Weight; Celiac Disease; Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Muscle Fibers, Skeletal; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12 | 2000 |
Serum homocyst(e)ine levels in women with preeclampsia.
Topics: Adult; Birth Weight; Data Interpretation, Statistical; Female; Homocysteine; Humans; Infant, Newborn; Logistic Models; Parity; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Prognosis | 2000 |
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene as a new risk factor for placental vasculopathy.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; DNA Mutational Analysis; Female; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Odds Ratio; Oxidoreductases; Placenta; Pregnancy; Vascular Diseases | 2000 |
Maternal protein deficiency causes hypermethylation of DNA in the livers of rat fetuses.
Topics: Animals; Dietary Proteins; DNA Methylation; Female; Glucose Tolerance Test; Homocysteine; Liver; Pregnancy; Prenatal Exposure Delayed Effects; Protein Deficiency; Rats; Threonine | 2000 |
Elevated circulating homocyst(e)ine levels in placental vascular disease and associated pre-eclampsia.
Topics: Adult; Biomarkers; Birth Weight; Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Ultrasonography, Prenatal; Vascular Diseases | 2000 |
The 4G/4G polymorphism of the hypofibrinolytic plasminogen activator inhibitor type 1 gene: an independent risk factor for serious pregnancy complications.
Topics: Antibodies, Anticardiolipin; Female; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Retrospective Studies; Risk Factors | 2000 |
Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677T and A1298C mutations.
Topics: Abortion, Habitual; Alleles; Female; Fetal Blood; Fetal Death; Fetus; Gene Frequency; Genes, Essential; Genes, Lethal; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Phenotype; Point Mutation; Polymorphism, Genetic; Pregnancy; Pregnancy Outcome | 2000 |
Folic acid, folate and homocysteine: human intervention studies.
Topics: Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy | 2000 |
Maternal plasma homocysteine levels in women with preterm premature rupture of membranes.
Topics: Amino Acid Metabolism, Inborn Errors; Collagen; Female; Fetal Membranes, Premature Rupture; Homocysteine; Humans; Pregnancy | 2001 |
Targeted disruption of the methionine synthase gene in mice.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Base Sequence; Cardiovascular Diseases; DNA Primers; Embryonic and Fetal Development; Female; Folic Acid; Gene Targeting; Heterozygote; Homocysteine; Homozygote; Humans; Methionine; Mice; Mice, Knockout; Neural Tube Defects; Pregnancy; Risk Factors; Vitamin B 12 Deficiency | 2001 |
Melatonin counteracts potentiation by homocysteine of KCL-induced vasoconstriction in human umbilical artery: relation to calcium influx.
Topics: Antioxidants; Calcium Signaling; Cardiovascular Diseases; Drug Interactions; Female; Free Radical Scavengers; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Mannitol; Melatonin; Potassium Chloride; Pregnancy; Umbilical Arteries; Vasoconstriction | 2001 |
Oxidized and free whole blood thiols in preeclampsia.
Topics: Adult; Cysteine; Dipeptides; Female; Glutathione; HELLP Syndrome; Homocysteine; Humans; Infant, Newborn; Lipid Peroxidation; Oxidation-Reduction; Oxidative Stress; Pre-Eclampsia; Pregnancy; Reference Values; Sulfhydryl Compounds | 2001 |
Homocysteine and human reproduction.
Topics: Culture Techniques; Female; Folic Acid; History, 17th Century; History, 20th Century; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Reproduction | 2000 |
Homocysteinaemia during pregnancy and placental disease.
Topics: Adult; Female; Fetal Death; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Humans; Placenta; Placenta Diseases; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 2000 |
Hypercoagulable thrombophilic defects and hyperhomocysteinemia in patients with recurrent pregnancy loss.
Topics: Abortion, Habitual; Activated Protein C Resistance; Adult; Factor V; Female; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Thrombophilia | 2001 |
Plasma folate, vitamin B(12), and homocyst(e)ine concentrations in preeclamptic and normotensive Peruvian women.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Odds Ratio; Peru; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Surveys and Questionnaires; Vitamin B 12 | 2001 |
Longitudinal vitamin and homocysteine levels in normal pregnancy.
Topics: Case-Control Studies; Female; Follow-Up Studies; Gestational Age; Homocysteine; Humans; Nutritional Status; Postpartum Period; Pregnancy; Reference Values; Vitamins | 2001 |
Mutations in the gene for methylenetetrahydrofolate reductase, homocysteine levels, and vitamin status in women with a history of preeclampsia.
Topics: Birth Weight; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Primers; Electrophoresis, Polyacrylamide Gel; Female; Folic Acid; Genotype; Gestational Age; HELLP Syndrome; Homocysteine; Humans; Infant, Newborn; Linear Models; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Pre-Eclampsia; Pregnancy; Radioimmunoassay; Regression Analysis; Vitamin B 12 | 2001 |
[Effects of homocysteine on post-implantation rat embryo cultured in vitro].
Topics: Animals; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Homocysteine; In Vitro Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens | 2001 |
Reduced vitamin B12 binding by transcobalamin II increases the risk of neural tube defects.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Electrophoresis, Agar Gel; Female; Homocysteine; Humans; Middle Aged; Neural Tube Defects; Polymerase Chain Reaction; Polymorphism, Genetic; Pregnancy; Risk Factors; Statistics as Topic; Transcobalamins; Vitamin B 12 | 2001 |
[Folic acid levels, homocysteine and polymorphism of methylenetetrahydrofolate reductase enzyme (MTHFR) in patients with pre-eclampsia and eclampsia].
Topics: Adult; Case-Control Studies; Eclampsia; Female; Folic Acid; Genotype; Homocysteine; Humans; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Prospective Studies | 2001 |
[Homocysteinemia--its significance in gynecology and obstetrics].
Topics: Adolescent; Adult; Aged; Child; Climacteric; Congenital Abnormalities; Female; Homocysteine; Humans; Middle Aged; Postpartum Period; Pregnancy; Pregnancy Complications; Risk Factors | 2000 |
Umbilical cord and maternal plasma thiol concentrations in normal pregnancy.
Topics: Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Female; Homocysteine; Humans; Infant, Newborn; Pregnancy; Sulfhydryl Compounds; Umbilical Cord | 2001 |
Serum homocysteine at 16 weeks and subsequent preeclampsia.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Cohort Studies; Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Second | 2001 |
Effect of smoking on serum concentrations of total homocysteine and B vitamins in mid-pregnancy.
Topics: Female; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Smoking; Vitamin B Complex | 2001 |
Association of the C677T methylenetetrahydrofolate reductase mutation and elevated homocysteine levels with congenital cardiac malformations.
Topics: Amniotic Fluid; Chromatography, High Pressure Liquid; Electrophoresis, Agar Gel; Female; Fetal Heart; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Pregnancy | 2001 |
Homocysteine and methylmalonic acid as indicators of folate and vitamin B12 deficiency in pregnancy.
Topics: Adult; Biomarkers; Female; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency | 2001 |
Melatonin suppresses homocysteine enhancement of serotonin-induced vasoconstriction in the human umbilical artery.
Topics: Antioxidants; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Ferrous Compounds; Homocysteine; Humans; Melatonin; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Serotonin; Umbilical Arteries; Vasoconstriction | 2001 |
Homocysteine and methylmalonic acid levels in pregnant Nepali women. Should cobalamin supplementation be considered?
Topics: Adolescent; Adult; Biomarkers; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Nepal; Nutritional Status; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Elevated plasma homocysteine in early pregnancy: a risk factor for the development of severe preeclampsia.
Topics: Adult; Biomarkers; Case-Control Studies; Cohort Studies; Confidence Intervals; Female; Homocysteine; Humans; Incidence; Odds Ratio; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Prenatal Care; Probability; Reference Values; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index | 2001 |
Total homocysteine is making its way into pediatric laboratory diagnostics.
Topics: Adult; Avitaminosis; Child; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylmalonic Acid; Pediatrics; Pregnancy; Vitamin B 12 | 2001 |
Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice.
Topics: Animals; Arsenates; Arsenicals; Arsenites; Cacodylic Acid; Carrier Proteins; Dose-Response Relationship, Drug; Female; Fetal Resorption; Folate Receptors, GPI-Anchored; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Mice; Mice, Knockout; Neural Tube Defects; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Cell Surface; Teratogens | 2001 |
[Study on the relationship between methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine level in pregnancy induced hypertension patients].
Topics: Adult; Female; Homocysteine; Humans; Hypertension; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pregnancy; Pregnancy Complications, Cardiovascular | 2000 |
The relation between plasma homocysteine concentration and methylenetetrahydrofolate reductase gene polymorphism in pregnant women.
Topics: Adult; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, First | 2001 |
Polymorphisms in genes involved in folate metabolism as risk factors for NTDs.
Topics: Adult; Carrier Proteins; Case-Control Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Italy; Male; Membrane Proteins; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pregnancy | 2001 |
The Hordaland Homocysteine Studies.
Topics: Adult; Aged; Aging; Blood Pressure; Cardiovascular Diseases; Cholesterol; Coffee; Cohort Studies; Diet; Exercise; Female; Homocysteine; Humans; Life Style; Male; Middle Aged; Norway; Pregnancy; Pregnancy Outcome; Risk Factors; Sex Characteristics; Surveys and Questionnaires; Vitamins | 2001 |
Effect of folic acid supplements on homocysteine concentration in plasma of gestating sows.
Topics: Animals; Dietary Supplements; Female; Folic Acid; Homocysteine; Pregnancy; Pregnancy, Animal; Random Allocation; Swine | 2001 |
Maternal and fetal plasma homocysteine concentrations at birth: the influence of folate, vitamin B12, and the 5,10-methylenetetrahydrofolate reductase 677C-->T variant.
Topics: Female; Fetal Blood; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Labor, Obstetric; Methylenetetrahydrofolate Reductase (NADPH2); Osmolar Concentration; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Vitamin B 12 | 2002 |
Hyperhomocysteinemia is common in patients with antiphospholipid syndrome and may contribute to expression of major thrombotic events.
Topics: Abortion, Habitual; Adult; Aged; Antiphospholipid Syndrome; Chi-Square Distribution; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pregnancy; Risk; Thromboembolism | 2002 |
Homocysteine levels in pregnant women who smoke cigarettes.
Topics: Abortion, Spontaneous; Abruptio Placentae; Congenital Abnormalities; Female; Fetal Death; Fetal Growth Retardation; Homocysteine; Humans; Models, Biological; Pregnancy; Smoking; Thromboembolism | 2001 |
Stability of total plasma homocysteine in perinatology.
Topics: Anticoagulants; Blood Preservation; Citric Acid; Female; Homocysteine; Humans; Infant, Newborn; Placenta; Pregnancy; Refrigeration; Specimen Handling; Time Factors | 2002 |
Investigation of the effects of folate deficiency on embryonic development through the establishment of a folate deficient mouse model.
Topics: Animals; Body Weight; Cleft Palate; Disease Models, Animal; Female; Folic Acid; Folic Acid Deficiency; Heart Defects, Congenital; Homocysteine; Male; Mice; Mice, Inbred ICR; Neural Tube Defects; Pregnancy | 2002 |
Elevated plasma homocysteine in early pregnancy: a risk factor for the development of severe preeclampsia.
Topics: Female; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Risk Factors | 2002 |
Folic acid, Vitamin B(12), and homocysteine in smoking and non-smoking pregnant women.
Topics: Cross-Sectional Studies; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Pregnancy; Pregnancy Complications; Reference Values; Smoking; Vitamin B 12 | 2002 |
Homocysteine and cellular fibronectin are increased in preeclampsia, not transient hypertension of pregnancy.
Topics: Female; Fibronectins; Homocysteine; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular | 2001 |
Perinatal reference intervals for plasma homocysteine and factors influencing its concentration.
Topics: Adult; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Fetal Blood; Homocysteine; Humans; Infant, Newborn; Life Style; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Physiological Phenomena; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Postpartum Period; Pregnancy; Reference Values; Smoking | 2002 |
The effect of N-acetylated DL-penicillamine and DL-homocysteine thiolactone on the mercury distribution in adult rats, rat foetuses and macaca monkeys after exposure to methyl mercuric chloride.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Female; Fetus; Haplorhini; Homocysteine; Kidney; Liver; Macaca fascicularis; Methylmercury Compounds; Penicillamine; Placenta; Pregnancy; Rats | 1976 |
Changes in glycogen phosphorylase activity and glycogen levels of mouse cerebral cortex during convulsions induced by homocysteine.
Topics: Animals; Cerebral Cortex; Female; Glycine; Glycogen; Homocysteine; Mice; Mice, Inbred Strains; Phenobarbital; Phosphorylases; Pregnancy; Seizures; Spectrometry, Fluorescence | 1975 |
Alleviation of inhibitory action of 5-bromode-oxyuridine by methionine in early chick embryos.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Bromodeoxyuridine; Chick Embryo; Female; Fetal Diseases; Heart; Homocysteine; Methionine; Nervous System; Pregnancy | 1975 |
Hyperhomocysteinaemia and recurrent spontaneous abortion or abruptio placentae.
Topics: Abortion, Habitual; Abruptio Placentae; Adult; Female; Homocysteine; Humans; Pregnancy; Recurrence | 1992 |
Simultaneous measurement by HPLC of the excitatory amino acid transmitter candidates homocysteate and homocysteine sulphinate supports a predominant astrocytic localisation.
Topics: Amino Acids; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Female; Homocysteine; Mice; Neurotransmitter Agents; Pregnancy | 1992 |
Homocysteate and homocysteine sulfinate, excitatory transmitter candidates present in rat astroglial cultures.
Topics: Animals; Animals, Newborn; Astrocytes; Bucladesine; Chromatography, High Pressure Liquid; Female; Homocysteine; Immunohistochemistry; Neuroglia; Neurotransmitter Agents; Pregnancy; Rats | 1992 |
Decreased serum homocysteine in pregnancy.
Topics: Adult; Female; Gestational Age; Homocysteine; Humans; Pregnancy | 1992 |
Intrauterine growth retardation, perinatal death, and maternal homocysteine levels.
Topics: Abortion, Spontaneous; Female; Fetal Growth Retardation; Homocysteine; Homocystinuria; Humans; Pregnancy; Pregnancy Complications | 1992 |
Neural-tube defects and derangement of homocysteine metabolism.
Topics: Female; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy | 1991 |
Enhancement by L-methionine on the contractile response of uterine segments to acetylcholine and high KCl is mainly due to enhancement of Ca uptake.
Topics: Acetylcholine; Animals; Calcium; Female; Homocysteine; In Vitro Techniques; Methionine; Potassium Chloride; Pregnancy; Rats; Tubercidin; Uterine Contraction; Uterus | 1990 |
Homocysteinemia due to folate deficiency.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Pregnancy; Protein Binding | 1987 |
Total homocyst(e)ine in plasma and amniotic fluid of pregnant women.
Topics: Adult; Amniotic Fluid; Female; Homocysteine; Homocystine; Humans; Pregnancy; Protein Binding | 1986 |
Thin-layer chromatographic screening of amino acids in plasma and urine of newborns.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Blood Proteins; Chromatography, Thin Layer; Female; Glycine; Homocysteine; Humans; Indicators and Reagents; Infant, Newborn; Infant, Premature; Lysine; Methionine; Phenylalanine; Pregnancy; Proteinuria; Tyrosine; Ultrafiltration | 1974 |
Absence of cystathionase in human fetal liver: is cystine essential?
Topics: Amino Acids; Brain; Cystine; Dietary Proteins; Female; Fetus; Homocysteine; Humans; Hydro-Lyases; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Liver; Methionine; Placenta; Pregnancy; Transferases | 1970 |