homocysteine and Nerve Degeneration

homocysteine has been researched along with Nerve Degeneration in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's20 (60.61)29.6817
2010's12 (36.36)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Caruso, P; Gazzin, S; Giuffré, M; Moretti, R; Tiribelli, C1
Hohberger, B; Jünemann, A; Rejdak, R1
Adamkov, M; Kalenska, D; Kovalska, L; Kovalska, M; Lehotsky, J; Tatarkova, Z; Tomascova, A; Tothova, B1
Bhattacharya, P; Borah, A; Dutta, A; Justin-Thenmozhi, A; Manivasagam, T; Mazumder, MK; Paul, R; Phukan, BC1
de Jager, CA; Douaud, G; Jacoby, R; Nichols, TE; Refsum, H; Smith, AD; Smith, SM1
Givvimani, S; Kalani, A; Kamat, PK; Sathnur, PB; Tyagi, N; Tyagi, SC1
Ahmadi, M; Balkaya, M; Cardozo-Pelaez, F; Cox, D; Eckart, S; Endres, M; Gay, SB; Gertz, K; Harms, C; Hellweg, R; Hörtnagl, H; Jaenisch, R; Juckel, G; Kempermann, G; Kronenberg, G; Linhart, H; Sobol, RW; Sohr, R; Wilson, SH; Winter, B1
Fuchs, D; Greilberger, J; Greilberger, M; Koidl, C; Lamprecht, M; Leblhuber, F; Oettl, K; Schroecksnadel, K1
Agnati, LF; Fuxe, K; Genedani, S; Guidolin, D; Leo, G; Piron, L; Rivera, A1
Kifle, L; Ortiz, D; Shea, TB1
Barchak, AG; Busanello, EN; Camargo, D; Carrion, MJ; da Costa, JC; Dalbem, A; de Mello Rieder, CR; de Sousa Miguel, SR; dos Santos, EF; Miglioranza, A; Rosa, C; Saute, J; Vargas, CR; Wajner, M; Zanatta, A1
Druga, R; Folbergrová, J; Haugvicová, R; Otáhal, J; Tsenov, G1
Alexopoulos, P; Bleich, S; Günther, F; Jessen, F; Kneib, T; Kornhuber, J; Kurz, A; Lewczuk, P; Peters, O; Popp, J; Richter-Schmidinger, T; Wiltfang, J; Wolf, S1
Dillmann, U; Fassbender, K; Herrmann, W; Kostopoulos, P; Obeid, R; Schadt, A1
Butterfield, DA; Calabrese, V; Cornelius, C; Lentile, R; Mancuso, C; Stella, AM1
Agnati, LF; Andreoli, N; Baldelli, E; Biagini, G; Fuxe, K; Leo, G1
Jang, Y; Kwon, YH; Park, YJ1
Prakasam, A; Ramesh, BN; Rao, KS; Rao, TS; Sambamurti, K1
Farkas, M; Ineichen, B; Jelcic, I; Jung, H; Keskitalo, S; Kühnlein, P; Linnebank, M; Ludolph, AC; Petersen, J; Semmler, A; Weller, M1
Müller, T1
Borowczyk, K; Jakubowski, H; Shih, DM1
Lyons-Weiler, J; Rogers, E; Shea, TB1
Folbergrová, J; Haugvicová, R; Langmeier, M; Mares, P; Pokorný, J1
Ashline, D; Collins, SC; Dhitavat, S; Ho, PI; Ortiz, D; Rogers, E; Shea, TB1
Cardozo-Pelaez, F; Chan, SL; Chrest, FJ; Emokpae, R; Gorospe, M; Kruman, II; Mattson, MP; Smilenov, L; Wersto, RP1
Kuhn, W; Müller, T; Renger, K1
Agnati, LF; Ferré, S; Filaferro, M; Franco, R; Fuxe, K; Galantucci, M; Genedani, S; Mora, F; Rasio, G; Saltini, S1
Hefter, H; Hueber, R; Jost, WH; Leenders, KL; Müller, T; Odin, P; Schwarz, J1
Druga, R; Folbergrová, J; Haugvicová, R; Kubová, H; Mares, P; Otáhal, J1
Netto, CA; Salbego, CG; Tagliari, B; Wyse, AT; Zamin, LL1
Blandini, F; Martignoni, E; Nappi, G; Pacchetti, C; Tassorelli, C; Zangaglia, R1
Lamberti, P; Logroscino, G; Samarelli, V; Serlenga, L; Simone, IL; Tortelli, R; Zoccolella, S1
Au, R; Beiser, AS; D'Agostino, RB; DeCarli, C; Jacques, PF; Rosenberg, IH; Selhub, J; Seshadri, S; Wolf, PA; Yoshita, M1

Reviews

7 review(s) available for homocysteine and Nerve Degeneration

ArticleYear
Homocysteine in Neurology: A Possible Contributing Factor to Small Vessel Disease.
    International journal of molecular sciences, 2021, Feb-19, Volume: 22, Issue:4

    Topics: Animals; Brain; Cerebrovascular Disorders; Homocysteine; Humans; Inflammation; Nerve Degeneration; Oxidative Stress

2021
[Significance of Homocysteine in Glaucoma].
    Klinische Monatsblatter fur Augenheilkunde, 2018, Volume: 235, Issue:2

    Topics: Endothelium, Vascular; Epigenesis, Genetic; Exercise; Eye; Feeding Behavior; Glaucoma; Glaucoma, Open-Angle; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Nerve Degeneration; Optic Atrophy; Risk Factors; Vascular Resistance; Weight Loss

2018
Neuronutrition and Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 19, Issue:4

    Topics: Aged; Alcohol Drinking; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Avitaminosis; Brain; Diet; Energy Intake; Female; Homocysteine; Humans; Hypercholesterolemia; Male; Middle Aged; Nerve Degeneration; Nutrition Therapy; Oxidative Stress; Phosphorylation; Point Mutation; Vitamin E

2010
Motor complications, levodopa metabolism and progression of Parkinson's disease.
    Expert opinion on drug metabolism & toxicology, 2011, Volume: 7, Issue:7

    Topics: Animals; Arteriosclerosis; Catechol O-Methyltransferase; Disease Progression; Dopamine; Dyskinesias; Enzyme Inhibitors; Free Radicals; Homocysteine; Humans; Levodopa; Nerve Degeneration; Parkinson Disease; Synaptic Transmission

2011
Homocysteine, folate deprivation and Alzheimer neuropathology.
    Journal of Alzheimer's disease : JAD, 2002, Volume: 4, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Nerve Degeneration

2002
Is levodopa toxic?
    Journal of neurology, 2004, Volume: 251 Suppl 6

    Topics: Animals; Dose-Response Relationship, Drug; Homocysteine; Humans; Levodopa; Nerve Degeneration; Neurotoxins; Oxidative Stress; Parkinson Disease; Substantia Nigra

2004
Homocysteine and Parkinson's disease: a dangerous liaison?
    Journal of the neurological sciences, 2007, Jun-15, Volume: 257, Issue:1-2

    Topics: Brain; Brain Diseases, Metabolic; Causality; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Nerve Degeneration; Parkinson Disease

2007

Trials

1 trial(s) available for homocysteine and Nerve Degeneration

ArticleYear
Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Jun-04, Volume: 110, Issue:23

    Topics: Alzheimer Disease; Bayes Theorem; England; Hippocampus; Homocysteine; Humans; Image Processing, Computer-Assisted; Linear Models; Longitudinal Studies; Magnetic Resonance Imaging; Nerve Degeneration; Temporal Lobe; Vitamin B Complex

2013

Other Studies

25 other study(ies) available for homocysteine and Nerve Degeneration

ArticleYear
Association of Induced Hyperhomocysteinemia with Alzheimer's Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury.
    Neurochemical research, 2018, Volume: 43, Issue:9

    Topics: Alzheimer Disease; Animals; Cerebral Cortex; Homocysteine; Hyperhomocysteinemia; Male; Nerve Degeneration; Rats; Rats, Wistar; Reperfusion Injury

2018
Accumulation of Cholesterol and Homocysteine in the Nigrostriatal Pathway of Brain Contributes to the Dopaminergic Neurodegeneration in Mice.
    Neuroscience, 2018, 09-15, Volume: 388

    Topics: Animals; Cholesterol; Corpus Striatum; Diet; Dopaminergic Neurons; Homocysteine; Hypercholesterolemia; Male; Mice; Motor Activity; Nerve Degeneration; Neural Pathways; Parkinsonian Disorders; Substantia Nigra

2018
Hydrogen sulfide attenuates neurodegeneration and neurovascular dysfunction induced by intracerebral-administered homocysteine in mice.
    Neuroscience, 2013, Nov-12, Volume: 252

    Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain; Gasotransmitters; Homocysteine; Hydrogen Sulfide; Inflammation; Injections, Intraventricular; Male; Mice; Nerve Degeneration; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction

2013
Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Jul-09, Volume: 28, Issue:28

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Brain-Derived Neurotrophic Factor; Cell Culture Techniques; Cells, Cultured; Cerebral Cortex; Deoxyuracil Nucleotides; Embryo, Mammalian; Exploratory Behavior; Folic Acid Deficiency; Glutathione; Hippocampus; Homocysteine; Maze Learning; Methionine; Mice; Nerve Degeneration; Neurons; Neurotransmitter Agents; Swimming; Uracil-DNA Glycosidase

2008
Malondialdehyde, carbonyl proteins and albumin-disulphide as useful oxidative markers in mild cognitive impairment and Alzheimer's disease.
    Free radical research, 2008, Volume: 42, Issue:7

    Topics: Aged; Alzheimer Disease; Biomarkers; Case-Control Studies; Cognition Disorders; Disulfides; Female; Folic Acid; Homocysteine; Humans; Male; Malondialdehyde; Middle Aged; Neopterin; Nerve Degeneration; Oxidative Stress; Protein Carbonylation; Serum Albumin; Severity of Illness Index; Vitamin B 12

2008
Common key-signals in learning and neurodegeneration: focus on excito-amino acids, beta-amyloid peptides and alpha-synuclein.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:8

    Topics: alpha-Synuclein; Amyloid beta-Peptides; Animals; Brain; Dopamine; Glutamic Acid; Homocysteine; Humans; Learning; Models, Neurological; Nerve Degeneration; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Protein Conformation; Protein Multimerization; Signal Transduction

2009
Deprivation of folate and B12 increases neurodegeneration beyond that accompanying deprivation of either vitamin alone.
    Journal of Alzheimer's disease : JAD, 2009, Volume: 16, Issue:3

    Topics: Calcium; Cell Line, Tumor; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Nerve Degeneration; Neuroblastoma; Neurons; Reactive Oxygen Species; Vitamin B 12; Vitamin B 12 Deficiency

2009
Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson's disease.
    Metabolic brain disease, 2009, Volume: 24, Issue:2

    Topics: Analysis of Variance; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Matched-Pair Analysis; Middle Aged; Nerve Degeneration; Parkinson Disease; Reference Values; Statistics, Nonparametric; Vitamin B 12

2009
Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats.
    Brain research, 2009, Jun-01, Volume: 1273

    Topics: Aging; Animals; Brain; Convulsants; Cytoprotection; Drug Administration Schedule; Drug Interactions; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Homocysteine; Male; Nerve Degeneration; Neuroprotective Agents; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus; Treatment Outcome

2009
Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia.
    Journal of the American Geriatrics Society, 2009, Volume: 57, Issue:4

    Topics: Aged; Amyloid beta-Peptides; Biomarkers; Chromatography, High Pressure Liquid; Creatinine; Dementia; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Germany; Homocysteine; Humans; Immunoassay; Linear Models; Male; Middle Aged; Nephelometry and Turbidimetry; Nerve Degeneration; Peptide Fragments; tau Proteins; Vitamin B 12

2009
Methylation status and neurodegenerative markers in Parkinson disease.
    Clinical chemistry, 2009, Volume: 55, Issue:10

    Topics: Aged; alpha-Synuclein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Nerve Degeneration; Parkinson Disease; Peptide Fragments; S-Adenosylhomocysteine; S-Adenosylmethionine; Substantia Nigra; Ultrasonography; Vitamin B 6

2009
Redox homeostasis and cellular stress response in aging and neurodegeneration.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 610

    Topics: Acetylcarnitine; Aging; Animals; Carbon Monoxide; Gene Regulatory Networks; Heme Oxygenase-1; Homeostasis; Homocysteine; HSP70 Heat-Shock Proteins; Humans; Nerve Degeneration; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Stress, Physiological

2010
Homocysteine potentiates seizures and cell loss induced by pilocarpine treatment.
    Neuromolecular medicine, 2010, Volume: 12, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Behavior, Animal; Disease Models, Animal; Epilepsy, Temporal Lobe; Fluoresceins; Hippocampus; Homocysteine; Humans; Male; Nerve Degeneration; Organic Chemicals; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

2010
Protective effect of isoflavones against homocysteine-mediated neuronal degeneration in SH-SY5Y cells.
    Amino acids, 2010, Volume: 39, Issue:3

    Topics: Alzheimer Disease; Apoptosis; Cell Line, Tumor; Endoplasmic Reticulum; Homocysteine; Humans; Isoflavones; Nerve Degeneration; Neurons; Protective Agents; S-Adenosylhomocysteine

2010
The thermolabile variant of 5,10-methylenetetrahydrofolate reductase is a possible risk factor for amyotrophic lateral sclerosis.
    Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2011, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Amyotrophic Lateral Sclerosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Isoenzymes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nerve Degeneration; Risk Factors; Temperature; Young Adult

2011
Metabolism and neurotoxicity of homocysteine thiolactone in mice: evidence for a protective role of paraoxonase 1.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 30, Issue:2

    Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Brain; Epilepsy; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kidney; Liver; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Degeneration; Spleen

2012
Neuronal cell death in hippocampus induced by homocysteic acid in immature rats.
    Epilepsia, 2003, Volume: 44, Issue:3

    Topics: Animals; Animals, Newborn; Apoptosis; Cell Count; Cell Nucleus; Cerebral Cortex; Dentate Gyrus; Hippocampus; Homocysteine; Male; Nerve Degeneration; Neuroglia; Neurons; Pyramidal Cells; Rats; Rats, Wistar; Seizures

2003
Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine.
    Neurobiology of disease, 2003, Volume: 14, Issue:1

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Folic Acid Deficiency; Homocysteine; Humans; Mice; Nerve Degeneration; Neurons; Oxidative Stress; Reactive Oxygen Species; Tumor Cells, Cultured

2003
Cell cycle activation linked to neuronal cell death initiated by DNA damage.
    Neuron, 2004, Feb-19, Volume: 41, Issue:4

    Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Colchicine; DNA Damage; DNA-Binding Proteins; Etoposide; Female; Homocysteine; Male; Methotrexate; Mice; Nerve Degeneration; Neurons; Protein Serine-Threonine Kinases; Rats; Staurosporine; Tumor Suppressor Proteins

2004
Levodopa-associated increase of homocysteine levels and sural axonal neurodegeneration.
    Archives of neurology, 2004, Volume: 61, Issue:5

    Topics: Action Potentials; Aged; Antiparkinson Agents; Axons; Chromatography, High Pressure Liquid; Electrophysiology; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Nerve Degeneration; Neural Conduction; Parkinson Disease; Sural Nerve

2004
Studies on homocysteine plasma levels in Alzheimer's patients. Relevance for neurodegeneration.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Female; Homocysteine; Humans; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2005
Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate.
    Experimental neurology, 2005, Volume: 192, Issue:2

    Topics: Amino Acids; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Brain; Brain Chemistry; Brain Injuries; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Functional Laterality; Glucose; Glycogen; Homocysteine; Lactic Acid; Male; Nerve Degeneration; Organic Chemicals; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures; Time Factors; Xanthenes

2005
Homocysteine increases neuronal damage in hippocampal slices receiving oxygen and glucose deprivation.
    Metabolic brain disease, 2006, Volume: 21, Issue:4

    Topics: Animals; Brain Ischemia; Cell Death; Glucose; Hippocampus; Homocysteine; Homocystinuria; L-Lactate Dehydrogenase; Male; Nerve Degeneration; Organ Culture Techniques; Oxygen; Rats; Rats, Wistar; Reperfusion Injury

2006
Elevated plasma homocysteine levels in patients with amyotrophic lateral sclerosis.
    Neurology, 2008, Jan-15, Volume: 70, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Biomarkers; Central Nervous System; Comorbidity; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nerve Degeneration; Predictive Value of Tests; Risk Factors; Sensitivity and Specificity; Up-Regulation; Vitamin B 12

2008
Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study.
    Archives of neurology, 2008, Volume: 65, Issue:5

    Topics: Aged; Atrophy; Biomarkers; Brain Infarction; Cerebral Cortex; Cohort Studies; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Massachusetts; Middle Aged; Nerve Degeneration; Nerve Fibers, Myelinated; Predictive Value of Tests; Prognosis

2008