homocysteine has been researched along with Hyperhomocysteinemia in 2462 studies
*Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated ( [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.04) | 18.7374 |
| 1990's | 104 (4.22) | 18.2507 |
| 2000's | 1358 (55.16) | 29.6817 |
| 2010's | 787 (31.97) | 24.3611 |
| 2020's | 212 (8.61) | 2.80 |
| Authors | Studies |
|---|---|
| Fast, W; Hong, L | 1 |
| Cheng, M; Fu, C; Li, X; Shi, Y; Wang, Y; Xue, H; Yan, Q; Zhu, D | 1 |
| Aiello, V; Angelini, A; Capelli, I; Cappuccilli, ML; Cianciolo, G; Croci Chiocchini, AL; Iacovella, F; Magnoni, G; Mancini, R; Napoletano, A; Troiano, A | 1 |
| da Silva Scarton, SR; de Lion Siervo, GEM; Deminice, R; Dos Santos, DP; Erthal, RP; Fernandes, GSA; Frigoli, GF; Ribeiro, DF; Seiva, FRF; Staurengo-Ferrari, L; Verri, WA | 1 |
| Al-Shabrawey, M; DeAngelis, MM; Kim, IK; Kira, D; Mohamed, R; Owen, LA; Rajpurohit, P; Samra, YA; Shakoor, A; Sheibani, N; Tawfik, A | 1 |
| Bao, F; Cong, H; Cui, M; Ju, S; Shi, X | 1 |
| Faliva, MA; Fossari, F; Naso, M; Nichetti, M; Perna, S; Peroni, G; Rondanelli, M; Tartara, A; Vecchio, V | 1 |
| Guo, Y; Han, W; Jia, S; Liu, X; Sun, J; Wu, S; Yan, Z; Zhao, Y; Zhou, Y | 1 |
| Cao, J; Geng, HR; Lin, Y; Liu, L; Qiao, YN; Qu, YY; Xu, W; Zhang, X; Zhao, JY | 1 |
| Bruin, N; Geisslinger, G; Nieraad, H; Pannwitz, N; Till, U | 1 |
| Bhat, OM; Huang, D; Li, G; Li, N; Li, PL; Ritter, JK; Zou, Y | 1 |
| Barra, M; Borriello, M; Cassinese, A; Chianese, F; Coppola, A; D'Angelo, P; Ingrosso, D; Lombari, P; Marasso, SL; Perna, AF; Tarabella, G; Vurro, D | 1 |
| de Paula, AMB; Engedal, K; Felício, LFF; Kristiansen, KM; Leão, LL; Monteiro-Junior, RS; Santos, SHS; Tangen, GG | 1 |
| Elmaghrabi, A; Gotway, G; Wolf, MTF; Wood, WD | 1 |
| Devi, NK; Garg, PR; Joshi, S; Longkumer, I; Rajkumari, S; Saraswathy, KN; Yadav, S | 1 |
| Dong, Y; He, Q; Hocher, B; Hocher, CF; Hong, X; Kraemer, BK; Li, J; Lv, Y; Xie, M; Yang, Y; Ye, X; Yuan, S; Zeng, Y | 1 |
| Gupta, JK; Srivastava, R; Varshney, KK; Verma, N | 1 |
| Brown, CJ; Elias, MF | 1 |
| Ostojic, SM | 1 |
| Bao, H; Cheng, X; Hu, F; Huang, X; Li, J; Wang, T; Yu, S; Zhou, W | 1 |
| He, H; Hou, A; Luo, M; Ran, S; Song, D; Tang, J; Tang, Y; Wang, H; Wang, T; Yan, X; Yang, R; Yu, B; Zhang, S | 1 |
| Cai, BQ; Huang, DD; Ren, YG; Yang, YP | 1 |
| Guieu, R; Mottola, G; Ruf, J | 1 |
| Choi, JH; Lee, MY; Lee, YT; Park, CH; Seo, JW; Yoon, KJ | 1 |
| Bjørk, MH; Bjørke-Monsen, AL; Storstein, A; Tysnes, OB; Ueland, PM | 1 |
| Fu, G; Gao, Y; Liu, X; Ming, L; Wang, X | 1 |
| Cao, C; Chen, H; Chen, X; Dou, Y; Huang, G; Huang, X; Jiang, Y; Li, M; Ma, X; Sheng, W; Wang, D; Wang, Y; Yan, W; Zhang, Y | 1 |
| Wang, AY; Wu, HHL | 1 |
| Gil, APR; Katsa, ME | 1 |
| Herrmann, M; Herrmann, W | 1 |
| Chen, YX; Qian, LJ; Tian, YR; Wang, SD; Wang, X; Wang, XT; Xie, F; Xue, BH; Zhang, ZQ; Zhao, Y | 1 |
| Mr, R; Paul, K | 1 |
| Bajic, Z; Djuric, DM; Matavulj, A; Ponorac, N; Skrbic, R; Sobot, T; Stojiljkovic, MP | 1 |
| García-Alfaro, P; Pérez-López, FR; Rodriguez, I | 1 |
| Ahmed, Z; Andrews, SC; Iqbal, K; Khan, MS; Qadir, SA; Saeedullah, A; Shahzad, B; Shahzad, M | 1 |
| Coutinho-Silva, R; Dos Santos, TM; Leite-Aguiar, R; Ramires Junior, OV; Savio, LEB; Silveira, JS; Wyse, ATS | 1 |
| Bogatova, K; Enikeev, D; Gerasimova, E; Giniatullin, R; Hermann, A; Sitdikova, G; Yakovleva, O | 1 |
| Cruciani-Guglielmacci, C; Daubigney, F; Denis, RG; Denom, J; Georgiadou, E; Janel, N; Kassis, N; Le Stunff, H; Magnan, C; Makaci, F; Meneyrol, K; Migrenne-Li, S; Paul, JL; Rachdi, L; Rodriguez Sanchez-Archidona, A; Rutter, GA; Thorens, B | 1 |
| Li, M; Ling, J; Tao, K; Tu, Y | 1 |
| Romdoni, R; Sargowo, D; Sugijo, H; Widjajanto, E | 1 |
| Bala, R; Budhwar, S; Prakash, N; Sachan, S; Verma, R | 1 |
| Djuric, D; Gopcevic, K; Kotlica, B; Labudovic Borovic, M; Medic, A; Stankovic, S; Stojanovic, M; Todorovic, D | 1 |
| Ara, R; Rahman, S; Sultana, MN | 1 |
| Abdul Ghani, SAB; Arul, K; Bee, GGB; Cheah, CC; Chow, PKH; Cook, SA; Lim, TR; Pei, HJ; Sandireddy, R; Shekeran, SG; Singh, BK; Singh, MK; Sinha, RA; Suzuki, A; Tikno, K; Tripathi, M; Wang, J; Widjaja, A; Wong, KA; Xiao, RP; Yen, PM; Zhang, X; Zhou, J | 1 |
| Chung, BY; Chung, EH; Eun, YS; Heo, NH; Kim, HO; Kim, JE; Kim, JY; Lee, SH; Lee, SY; Park, CW; Park, YL; Shin, MJ; Yang, NG | 1 |
| Lee, YT; Park, CH; Rhim, HC; Yoo, TK; Yoon, KJ | 1 |
| Cohen, E; Goldberg, E; Goldberg, I; Krause, I; Lerman, TT; Sochat, T | 1 |
| Igarashi, A; Inoue, S; Kimura, T; Machida, H; Minegishi, Y; Murano, H; Nakano, H; Nemoto, T; Nishiwaki, M; Otaki, Y; Sato, K; Sato, M; Shibata, Y; Tokairin, Y; Watanabe, M; Yamauchi, K; Yang, S | 1 |
| Li, C; Zhang, B | 1 |
| Balwani, M; Fanelli, MJ; Gouya, L; Longo, N; Petrides, PE; Phillips, J; Plutzky, J; Rhyee, S; Sardh, E; Sweetser, MT; Ventura, P | 1 |
| Cai, X; Li, N; Liu, Y; Yuan, Y | 1 |
| An, X; Deng, Y; Fan, R; Li, J; Li, Z; Liao, J; Wang, Y; Xia, Y; Yang, X | 1 |
| Yuan, F; Zheng, K | 1 |
| Burton, GJ; Capatina, N; Yung, HW | 1 |
| Jia, J; Li, T; Quan, M; Song, Y | 1 |
| Guéant, JL; Guéant-Rodriguez, RM; Oussalah, A; Rosenberg, I; Zuily, S | 1 |
| Deng, Y; Kong, J | 1 |
| Huang, X; Liu, D; Wu, M | 1 |
| Gambello, MJ; Gonzalez, A; Kožich, V; Li, H; Smith, GH; Sokolová, J | 1 |
| Benítez, S; Escolà-Gil, JC; Griñán, R; Julve, J; Rotllan, N | 1 |
| Gurecká, R; Koborová, I; Podracká, Ľ; Repiská, G; Šebeková, K | 1 |
| Guo, J; Jia, Y; Li, S; Zhu, Z | 1 |
| Åberg, F; Jula, A; Lundqvist, A; Männistö, V | 1 |
| Abdulhalim, EN; El-Bassyouni, HT; Hamed, K; Hashem, SA; Kamel, SM; Khedr, AA; Youness, ER | 1 |
| Asanidze, E; Kristesashvili, J; Urjumelashvili, M | 1 |
| Shen, Z; Zhang, Z; Zhao, W | 1 |
| Gospodarczyk, A; Gospodarczyk, N; Marczewski, K; Tkocz, M; Widuch, M; Zalejska-Fiolka, J | 1 |
| Chen, L; Chen, Y; He, Z; Huang, G; Li, J; Peng, L; Sun, H; Wang, J; Xiao, K; Xiao, L; Xv, L; Xv, Y | 1 |
| Cai, L; Kaddour-Djebbar, I; Raghavan, R; Rajpurohit, P; Samra, YA; Tawfik, A; Zaidi, Y | 1 |
| Han, H; Hu, X; Li, A; Li, R; Li, Y; Qin, Z; Song, W; Zhou, X | 1 |
| Chen, S; Fang, AP; He, TT; Huang, BX; Huang, RZ; Huang, ZH; Li, SY; Liu, XZ; Liu, ZY; Lu, XT; Luo, Y; Maierhaba, W; Mo, QW; Wang, YF; Wang, YN; Yang, MT; Zhang, XG; Zhu, HL | 1 |
| Gong, J; Li, Z; Ma, X; Xu, R; Zhang, L; Zhang, X | 1 |
| Park, HY; Song, BM; Song, S | 1 |
| Celermajer, DS; Chook, P; Guo, DS; Kwok, CYT; Lin, CQ; Poon, YKP; Woo, KS; Yin, YH | 1 |
| Asahina, M; Imaizumi, K; Kawano, M; Nakashima, S; Sakamoto, M; Sato, M; Shirouchi, B; Tanaka, Y; Tashiro, K; Yamaguchi, C | 1 |
| Chen, L; Han, X; Hu, L; Lu, Y; Yin, J; Yu, L | 1 |
| Chai, HT; Chang, CT; Chiu, LW; Friedman, M; Lin, CW; Lin, HC; Lin, PW; Salapatas, AM | 1 |
| Shi, B; Zhang, M; Zhao, M | 1 |
| Chandratheva, A; Chen, J; Coughlan, CH; Goodison, W; Murphy, E; Rees, A | 1 |
| Huang, W; Wen, C; Xu, R; Yu, X | 1 |
| Chen, GL; Li, L; Liu, H; Lv, L; Ma, Z; Tong, X | 1 |
| Bian, J; Jiao, X; Li, Y; Liu, G; Song, Y; Tang, B; Wang, X; Xie, X; Zhang, J; Zhao, Y | 1 |
| Bao, H; Chen, G; Cheng, X; Cheng, Z; Cui, Y; Ding, C; Hu, L; Huang, X; Huo, Y; Li, P; Qin, X; Sheng, C; Song, D; Tang, G; Wang, J; Wang, X; Wang, Z; Yao, C; Zhang, J | 1 |
| Andersson, U; Apostolopoulos, V; Gadanec, LK; Zulli, A | 1 |
| Chen, W; Feng, J; Ji, P; Liu, Y; Wan, H; Zhang, J | 1 |
| Bottiglieri, T; Fardo, DW; Johnson, SN; Qiao, Q; Rogers, CB; Sudduth, TL; Weekman, EM; Wilcock, DM; Xie, K | 1 |
| Banerjee, S; Bhat, A; Bissa, B; Chatterjee, B; Kaur, B; Lal, M; Nattarayan, V; Ramasamy, S; Roy, SS; Samaddar, S; Sharma, PK | 1 |
| Al-Khlaiwi, T; Almushawah, A; Alsomali, A; Habib, SA; Habib, SS | 1 |
| Gu, J; Lei, C; Zhang, M | 1 |
| Duan, XL; Wang, LB; Wang, XH; Wu, CY | 1 |
| Cai, X; Li, N; Luo, Q; Ren, Y; Wang, G; Wang, M; Yao, L; Yue, N; Zhao, J | 1 |
| Cui, K; Liu, J; Ruan, Y; Song, J; Tang, Z; Wang, S; Wang, T; Yang, J; Yu, Z | 1 |
| Ge, Y; Guo, W; Jia, X; Liu, F; Liu, J; Liu, X; Lu, W; Ma, X; Rong, D; Sun, G; Xiong, J; Zhang, H | 1 |
| Chen, J; Chen, Y; Deng, X; Leng, H; Ma, Z; Pan, L; Wu, K; Yin, Y; Zhang, HT | 1 |
| Choi, ST; Park, JH; Song, JS | 1 |
| Abd Al-Badri, HJ; Abdul-Hassan, M | 1 |
| Choi, ET; Cueto, R; Fang, P; Fu, H; Gao, C; Liu, L; Shao, Y; Shen, W; Wang, H; Wu, Q; Yang, WY; Yang, X | 1 |
| Kiouri, E; Kosmas, N; Pavlakis, G; Rallidi, T; Rallidis, LS; Zolindaki, M | 1 |
| Andreeva-Gateva, PA; Dimova, II; Mihaleva, ID | 1 |
| Cong, G; Hou, J; Jia, S; Ma, W; Yan, N; Yan, R; Yang, L; Yang, W; Zhang, N; Zhu, L | 1 |
| Chen, L; Cheng, J; Hu, H; Li, F; Li, X; Liu, S; Sun, X; Tian, F; Zhao, Z | 1 |
| Kumar, S; Singh, NK; Sonkar, SK; Tandon, R | 1 |
| Annunziata, MC; Donnarumma, M; Fabbrocini, G; Marasca, C | 1 |
| Deng, M; Guo, W; Jiang, Y; Ma, P; Ma, S; Mao, C; Nie, L; Sun, J; Sun, L; Wang, N; Xiong, J; Yang, A; Zhang, H | 1 |
| Chen, Z; He, S; Huang, Z; Li, R; Li, W; Liang, Z; Wang, S; Wu, H; Zhu, J | 1 |
| De Luca, G; Marcolongo, M; Nardin, M; Negro, F; Pergolini, P; Rolla, R; Tonon, F; Verdoia, M | 1 |
| Choi, G; Harrison, J; Kwok, T; Lam, L; Lee, J; Lee, R; Lee, V; Mok, V; Wu, Y; Yung, CY | 1 |
| Kachula, S; Korda, M; Mel'nyk, A; Nechiporuk, V; Pentiuk, N | 1 |
| Dos Santos, TM; Kolling, J; Netto, CA; Sanches, EF; Siebert, C; Wyse, ATS | 1 |
| Curcio, C; Giraldi, M; Paltrinieri, S; Scarpa, P | 1 |
| Li, H; Li, J; Lin, J; Liu, L; Wang, A; Wang, Y; Zhao, X; Zuo, Z | 1 |
| Abdel-Latif, Y; Badawy, E; El-Laithy, N; El-Naggar, M; El-Waseef, M; Hassan, H; Hussein, J | 1 |
| Finnell, RH; Hou, J; Huang, L; Jin, L; Lin, Y; Liu, Z; Ma, J; Mei, X; Nie, J; Qi, D; Saiyin, H; Si, W; Wang, H; Wang, J; Xu, W; Xue, Y; Ye, J; Zhang, T; Zhao, J; Zhao, S; Zhao, Y; Zhu, P | 1 |
| Budoff, MJ; Garg, PK; Guan, W; Karger, AB; Nomura, SO; Steffen, BT; Szklo, M; Tsai, MY | 1 |
| Chen, Y; Guo, X; Sun, Y; Yang, H; Yu, S; Zheng, L | 1 |
| Godfrey, O; Huang, X; Li, D; Zhang, C; Zhang, W; Zhao, Q | 1 |
| Cao, Y; Chai, J; Dai, H; Ji, D; Luo, C; Wang, W; Xue, K; Yan, W; Zhang, S; Zhang, X; Zhang, Y | 1 |
| Li, J; Luo, S; Shi, T; Tan, C; Wang, H; Wang, Y | 1 |
| Cheng, Y; Hou, J; Jiang, Y; Li, J; Ma, Y; Man, Z; Su, X; Sun, L; Tian, M; Tie, T; Zhang, S; Zhang, T; Zhang, Y | 1 |
| Braconnier, A; Desmons, A; Garnotel, R; Gillery, P; Jaisson, S; Rieu, P; Wynckel, A | 1 |
| Cao, L; Guo, Y; Zhu, Z | 2 |
| Chen, S; Furuta, Y; Hata, J; Hirakawa, Y; Honda, T; Kitazono, T; Ninomiya, T; Ohara, T; Oishi, E; Sakata, S; Shibata, M; Yoshida, D | 1 |
| Du, X; Li, K; Liang, L; Liu, Z; Song, L; Sun, R; Xiao, L | 1 |
| Beutel, ME; Blettner, M; Blom, HJ; Joachimsen, L; Lackner, KJ; Lagrèze, WA; Münzel, T; Nickels, S; Pfeiffer, N; Schulz, A; Wild, PS | 1 |
| Cui, Z; Jia, Y; Li, F; Li, S; Qi, L; Sun, L; Wang, Z; Zhao, X | 1 |
| Du, B; Huang, X; Li, D; Ren, B; Yue, L; Zhang, C; Zhang, W; Zhao, Q | 1 |
| Chen, X; Huang, X; Li, D; Ren, B; Shi, F; Wang, X; Yue, L; Zhang, C; Zhang, W; Zhao, Q; Zheng, C | 1 |
| Fiskum, G; Goodfellow, M; Li, F; Miller, C; Puche, A; Ramsue, L; Tchantchou, F | 1 |
| Bao, H; Cheng, X; Deng, H; Hu, X; Huang, X; Wan, K; Wang, D; Wang, H; Wu, Q; Xu, Z; Zhan, B; Zhang, Y | 1 |
| Cao, P; Gao, N; Lei, L; Li, L; Lin, L; Xu, R; Zhang, Y; Zhao, X | 2 |
| Boyina, HK; Boyina, S; Gangarapu, K; Kanala, DR; Pasangulapati, JP; Ravula, AR | 1 |
| Chang, G; Heizhati, M; Hong, J; Li, N; Luo, Q; Pan, F; Sun, L; Wang, L; Yue, N; Zhang, D; Zhou, L | 1 |
| Buzzetti, E; Corradini, E; Cuoghi, C; Di Pierro, E; Marcacci, M; Marchini, S; Pietrangelo, A; Ventura, P | 1 |
| Liu, H; Liu, Z; Ning, X; Wang, J; Xia, L; Xiong, Z; Yang, Y; Yao, X; Zhang, K; Zhang, Y; Zhao, T; Zhong, Y | 1 |
| Baptista, J; Ferin, R; Fontes, A; Lima, A; Martins, D; Pavão, ML; Santos, E | 1 |
| De Martinis, M; Fontanella, L; Ginaldi, L; Nocelli, C; Sirufo, MM | 1 |
| McCully, KS | 4 |
| Cho, S; Lee, JS | 1 |
| Bruzzese, L; Chefrour, M; Criado, C; Cuisset, T; Deharo, P; Fenouillet, E; Fromonot, J; Gastaldi, M; Gaubert, M; Gaudry, M; Guieu, R; Guiol, C; Kipson, N; Mace, P; Marlinge, M; Mottola, G; Paganelli, F; Ruf, J; Vairo, D | 1 |
| Ding, L; Liu, L; Zeng, J; Zhang, W; Zheng, Z; Zhou, K | 1 |
| Bogatova, K; Gerasimova, E; Hermann, A; Mukhtarova, R; Shakhmatova, V; Sitdikova, G; Yakovlev, A; Yakovleva, O; Ziyatdinova, G | 1 |
| Ali, MM; Bianco, FM; Cristoforo, GP; Frederick, P; Gangemi, A; Haloul, M; Hassan, C; Mahmoud, AM; Masrur, M; Mirza, MI; Naquiallah, D; Phillips, SA; Qureshi, M; Vinjamuri, SJ | 1 |
| Ben, Z; Chen, S; Li, X; Ruan, H; Wang, J; Zhan, J | 1 |
| Chen, L; He, Y; Jiang, P; Zhao, Y | 1 |
| George, AK; Homme, RP; Jovanovic, M; Singh, M; Stanisic, D; Tyagi, N; Tyagi, SC | 1 |
| Wang, L; Zhang, Y | 1 |
| George, AK; Singh, M; Smolenkova, I; Stanisic, D; Tyagi, SC | 1 |
| Hong, J; Hu, J; Huang, L; Jin, N; Pu, J; Rong, H; Wang, S; Xie, Y | 1 |
| Al-Shabrawey, M; Elsherbiny, NM; Samra, YA; Tawfik, A | 1 |
| Adamkov, M; Hnilicova, P; Kalenska, D; Kovalska, M; Lehotsky, J; Tomascova, A | 1 |
| Graban, A; Jakubowski, H; Kubalska, J; Perła-Kaján, J; Utyro, O | 1 |
| Cao, L; Deng, J; Guo, W; Liu, J; Liu, X; Wang, Q; Zhang, H | 1 |
| Cornett, EM; Fuller, MC; Jeha, GM; Kaye, AD; Kevil, CG; Lerner, ZI; Pham, AD; Sibley, GT; Urits, I; Viswanath, O | 1 |
| Chang, JY; Chiang, CP; Sun, A | 1 |
| Maiha, BB; Onyemelukwe, OU | 2 |
| Domi, E; Hoxha, B; Hoxha, M; Zappacosta, B | 1 |
| Al Amri, F; Al Hazmi, M; Al Saleb, A; Al Shehri, M; Al Turki, M; Al Yousef, MZ; Ferwana, M; Othman, F; Saeed, A | 1 |
| Chen, J; Chen, Y; Fan, S; Huang, B; Huang, Z; Liu, J; Shan, Z; Wei, X; Xie, Z; Zhang, X; Zhao, F; Zheng, Z | 1 |
| Chen, AF; Chen, R; He, S; Leng, Y; Shi, X; Zhang, Z; Zhou, X | 1 |
| Li, Y; Sun, D; Yao, D; Yin, D; Zhang, H; Zhao, Y | 1 |
| Chen, LQ; Chen, RY; Chen, XQ; Li, XZ; Lin, Q; Shen, YY; Wu, HY; Xu, QY; Zhu, XM; Zhu, Y | 1 |
| George, AK; Homme, RP; Mallonee, CJ; Molnar, J; Singh, M; Stanisic, D; Tyagi, SC | 1 |
| Bushnell, CD; Kim, HJ; Kim, HY; Kim, YS; Ryu, CH; Yoo, JS | 1 |
| Cynober, L; Deutz, NEP; Engelen, MPKJ; Ligthart-Melis, GC; Simbo, SY; Ten Have, GAM; Thaden, JJ | 1 |
| Paskaleva, D; Sandeva, M; Tufkova, S | 1 |
| Eyob, W; George, AK; Homme, RP; Sandhu, H; Singh, M; Stanisic, D; Tyagi, SC | 1 |
| Douillard, C; Grzych, G; Joncquel Chevalier Curt, M; Lannoy, J | 1 |
| Al-Shabrawey, M; Alhusban, S; Kira, D; Mohamed, R; Tawfik, A | 1 |
| Chen, M; Huang, P; Jiang, Z; Lin, N; Shi, H; Sun, X; Wang, L; Yang, S; Yu, R | 1 |
| Jiang, B; Yao, C; Yao, G; Zheng, N | 1 |
| Lu, Y; Sun, X; Wang, Q; Wang, Z; Zheng, L | 1 |
| Poddar, R | 1 |
| Kumar, M; Sandhir, R | 1 |
| Chan, SH; Chen, HI; Chen, YA; Chou, WC; Chu, PM; Hsieh, PL; Li, CW; Ou, HC; Pai, PY; Tsai, KL; Wu, SY | 1 |
| Andriichuk, V; Korda, M; Kovalchuk, O; Nechyporuk, V; Pentiuk, L | 1 |
| Dragnić, S; Kraljević, I; Mikhailidis, DP; Muzurović, E; Solak, M | 1 |
| Armin, M; Askari, G; Clark, CCT; Lotfi, K; Moradi, F; Rouhani, MH | 1 |
| Gabelli, C; Reffo, A | 1 |
| Guo, Y; Han, W; Jia, S; Liu, W; Sun, J; Wu, S; Yan, Z; Zhao, Y; Zhou, Y | 1 |
| Fishchuk, L; Gorovenko, N; Medvedieva, N; Rossokha, Z; Sheyko, L | 1 |
| De Luca, G; Gioscia, R; Marcolongo, M; Nardin, M; Negro, F; Saghir Afifeh, AM; Verdoia, M; Viglione, F | 1 |
| Gao, H; Hao, B; Premaratne, S; Su, X; Sun, L; Wang, S; Xu, H; Yang, T; Yao, J; Zhang, J; Zhang, W | 1 |
| Deharo, P; Fromonot, J; Guieu, R; Marlinge, M; Mottola, G; Paganelli, F; Ruf, J | 1 |
| Alli, AL; Chori, BS; Danladi, B; Inyang, BA; Nwegbu, MM; Odili, AN; Okoh, MP | 1 |
| Bedarf, J; Bidkhori, G; Ehrlich, SD; Hildebrand, F; Le Chatelier, E; Lee, S; Mardinoglu, A; Proctor, G; Rosario, D; Shoaie, S; Uhlen, M; Wüllner, U | 1 |
| Cai, J; Chen, Z; Cui, C; Fan, X; Geng, B; Gong, Y; Jiang, S; Xu, W | 1 |
| Guéant, JL; Jeannesson, E; Levy, J; Oussalah, A; Rodriguez-Guéant, RM; Wahl, D; Ziuly, S | 1 |
| Bjørklund, G; Chirumbolo, S; Dadar, M; Lenchyk, L; Lozynska, I; Lysiuk, R; Peana, M; Severin, B; Upyr, T | 1 |
| Alves, VS; Coutinho-Silva, R; Dos Santos, TM; Ramires Júnior, OV; Savio, LEB; Wyse, ATS | 1 |
| Bobermin, LD; Dos Santos, TM; Quincozes-Santos, A; Wyse, ATS | 1 |
| Chu, X; Dong, J; Guo, Y; Hou, C; Li, Z; Sun, F; Zhao, J | 1 |
| Aarsand, AK; Aguilera, P; Brunet, M; Deulofeu, R; García-Villoria, J; Gómez-Gómez, À; Pozo, OJ; Sandberg, S; To-Figueras, J; Wijngaard, R | 1 |
| Chen, JY; Shih, CC; Shih, YL | 1 |
| Anusree, VR; Chandran, M; Jaleel, A; Kumar, AA; Lakshmi, S; Pillai, MR; Satheesh, G; Simon, L; Vijayakumar, G | 1 |
| Gui, HL; Jiang, Q; Li, B; Si, X; Tan, DH; Tian, JL; Wang, L; Zhang, Y | 1 |
| Anamnart, C; Kitjarak, R | 1 |
| Dai, C; Fei, Y; Li, J; Shi, Y; Yang, X | 1 |
| Aday, AW; Christen, WG; Duran, EK; Kim, E; Manson, JE; Pradhan, AD; Ridker, PM; Van Denburgh, M | 1 |
| Beykirch, MK; Klein, M; Loehr, C; Molitor, B; Obermeier, Z; Petrides, PE; Schuhmann, E; Torkler, H | 1 |
| Adamkov, M; Baranovicova, E; Kalenska, D; Kovalska, L; Kovalska, M; Lehotsky, J; Tomascova, A | 1 |
| Agrawal, NR; Bala, R; Rajender, S; Singh, K; Singh, V; Verma, P; Verma, R; Yadav, N | 1 |
| Kalita, J; Misra, UK; Singh, VK | 1 |
| Chen, Y; Dong, H; Li, Y; Wang, S; Wang, X; Wu, J; Xu, Y; Zhang, B | 1 |
| Chu, M; Gao, J; Guo, L; Liu, L; Teng, J; Wang, Y; Zhang, L | 1 |
| Jin, YT; Lin, PY; Wu, YC; Wu, YH; Yang, JH | 1 |
| Elsherbiny, NM; Rajpurohit, P; Tawfik, A; Zaidi, Y | 1 |
| Cuoghi, C; Marcacci, M; Pietrangelo, A; Ricci, A; Ventura, P | 1 |
| Fu, C; Gao, Y; Wang, Q; Xia, H | 1 |
| Cao, YW; Diao, JY; Gao, TJ; Wu, HY; Yao, XW; You, PH | 1 |
| Bu, S; Chu, Y; Dai, H; Hu, F; Hu, P; Qiu, X; Sha, W; Yang, X | 1 |
| Avagimyan, A | 1 |
| Bobermin, LD; Dos Santos, TM; Quincozes-Santos, A; Siebert, C; Wyse, ATS | 1 |
| Cao, H; Cui, ZQ; Ge, JB; Gu, ZH; Hong, B; Hu, JL; Jin, XJ; Lv, XC; Qian, XL; Shen, L; Tang, MN; Tang, WQ; Yao, ZF; Zhang, J; Zhang, L; Zhou, J | 1 |
| Boyko, AN; Dubchenko, EA; Kiseleva, EV; Spirin, NN; Spirina, NN | 1 |
| Cao, Y; Chai, J; Ji, D; Liu, H; Liu, J; Luo, C; Wang, W; Wu, J; Wu, Y; Xue, K; Yan, W; Zhu, X | 1 |
| Ahsan, A; Chu, P; Han, G; Li, H; Lin, Y; Liu, S; Peng, J; Sun, B; Sun, Z; Tang, Z; Wu, J; Xi, Y; Zhang, Z; Zhou, Z | 1 |
| Katsiki, N; Mikhailidis, DP; Perez-Martinez, P | 1 |
| Ai, Y; Li, J; Liu, L; Peng, C; Sun, Z; Xiao, X | 1 |
| Chang, Y; Chen, Y; Dai, D; Guo, X; Li, Y; Sun, Y | 1 |
| Kumar, M; Modi, M; Sandhir, R | 1 |
| Hidaka, S; Ishioka, K; Kobayashi, S; Maesato, K; Mochida, Y; Moriya, H; Ohtake, T; Oka, M | 1 |
| Ding, R; Jiang, L; Jiang, Y; Lin, X; Wu, C; Xia, X; Yang, W; Zheng, S | 1 |
| Gupta, S; Vijayan, V | 1 |
| Arutjunyan, AV; Milyutina, YP; Pustygina, AV; Zaloznyaya, IV | 1 |
| Coppola, M; Mondola, R | 1 |
| Feng, X; Xu, Y | 1 |
| Padovani, D | 1 |
| Chen, AF; Chen, RF; Leng, YP; Li, XG; Li, XH; Li, YP; Ma, YS; Qiu, CF; Zeng, PY; Zhang, Z | 1 |
| Chai, R; Guo, X; Li, X; Li, Y; Liu, K; Peng, Y; Wu, J; Xuekelati, S; Yin, Y; Zhang, Y | 1 |
| Dong, JZ; Du, X; Gao, LJ; Hu, R; Jiang, CX; Liu, T; Long, DY; Lv, Q; Ning, M; Shang, MS; Tang, RB; Yang, XH; Yao, Y; Zhao, JH; Zhu, H | 1 |
| Li, L; Ma, L; Tang, Z | 1 |
| Al-Nafisee, D; Guo, W; Jia, S; Jia, X; Khalil, RA; Li, H; Li, Y; Liu, J; Liu, X; Lu, W; Ma, X; Rong, D; Sun, G; Xiong, J; Zhang, H | 1 |
| Ding, S; Sun, J; Wen, S; Zhou, J | 1 |
| Bandzeviciene, R; Bartkeviciene, D; Bartkeviciute, A; Boreikaite, E; Serapinas, D; Silkunas, M | 1 |
| Abraham, MR; Guo, X; Li, Z; Liu, Y; Sun, G; Sun, Y; Zheng, L | 1 |
| Dai, XL; Jin, MH; Liu, GC; Mi, NN; Ren, XY; Wang, J; Wang, SQ; Zhang, J | 1 |
| Cai, Z; Fu, Y; Kong, W; Liu, Z; Wang, X; Wang, Y; Yu, B; Yu, F; Zhang, L; Zhou, J | 1 |
| Belskikh, ES; Bulatetskiy, SV; Medvedev, DV; Ryabkov, AN; Uryasev, OM; Zvyagina, VI | 1 |
| Fu, Y; Kong, W; Wang, X | 1 |
| Kumar, KJ; Murthy, DS; Saldanha, K; Sushma, K; Vishwanath, P | 1 |
| Aguilar-Ros, A; Carson, BP; Díaz-Martínez, ÁE; García-González, Á; Iglesias-Gutiérrez, E; O'Gorman, DJ; Terrados, N; Úbeda, N; Venta, R | 1 |
| Guo, G; Liu, G; Sun, W; Zhao, J; Zheng, H | 1 |
| Ingenbleek, Y | 1 |
| DiPette, DJ; Skeete, J | 1 |
| Cao, Y; Ding, XM; Hao, XD; Ning, B; Ren, JR; Ren, SH; Wang, S; Wu, J; Zhen, ZG | 1 |
| Fang, Y; Li, Y; Niu, X; Wang, L; Zhang, W | 1 |
| Kim, J; Kim, JO; Kim, NK; Kim, OJ; Oh, SH; Park, HS; Ryu, CS; Shin, JW | 1 |
| Chen, H; Chen, J; Gu, Y; Liu, N; Yang, K; Zhao, J | 1 |
| Azad, MAK; Huang, P; Liu, G; Ren, W; Teklebrh, T; Yan, W; Yin, Y; Zhou, X | 1 |
| Farina, N; Hart, K; Jernerén, F; Tabet, N; Turner, C | 1 |
| Cecchet, D; Coracina, A; Kiwanuka, E; Puricelli, L; Tessari, P; Vettore, M | 1 |
| Absalom, AR; de Bock, GH; Gernaat, SAM; Huisman, MG; Izaks, GJ; van der Wal-Huisman, H; van Leeuwen, BL; Weerink, LBM | 1 |
| Baldessari, A; Genoud, V; Gionco, S; Quintana, I; Quintana, PG | 1 |
| Bjørnestad, EØ; Borsholm, RA; Bønaa, KH; Midttun, Ø; Nygård, O; Pedersen, ER; Seifert, R; Svingen, GFT; Tell, GS; Ueland, PM | 1 |
| Dong, Y; Liu, H; Luo, C; Sun, Q; Wang, H; Wang, W; Wu, Y; Xu, J; Zhang, H; Zhou, Y | 1 |
| Cassidy, RM; Chen, HM; Chen, JX; Li, JY; Li, R; Ning, Y; Soares, JC; Wang, N; Wang, SL; Zhang, LG; Zhang, XM; Zhang, XY; Zheng, Y; Zhou, SJ | 1 |
| Duan, Y; Huang, X; Kuang, YQ; Lin, D; Yang, Y | 1 |
| Di Luigi, L; Romanelli, F; Romano, M; Sansone, A; Sansone, M; Seraceno, S | 1 |
| Chang, Y; Guo, YZ; Jing, L; Tang, YS; Wang, YL; Yan, R; Zhang, JW; Zhang, JZ | 1 |
| Liu, J; Wang, G; Xu, Y; Zhang, Y | 1 |
| Jacques, PF; Livingston, K; Rogers, G; Rosenberg, IH; Scott, TM; Selhub, J; Troen, AM; Weiner, DE | 1 |
| Acikgoz, N; Arslan, AK; Cansel, M; Ermis, N; Karincaoglu, Y; Ozdemir, R; Pekdemir, H; Yagmur, J | 1 |
| Borowska, M; Dworacka, M; Krzyżagórska, E; Winiarska, H | 1 |
| de S Moreira, D; Figueiró, PW; Guma, FCR; Manfredini, V; Prezzi, CA; Rohden, F; Siebert, C; Wyse, ATS | 1 |
| Al-Bayyari, N; Hailat, R; Hamadneh, J; Hamadneh, S | 1 |
| Di Meco, A; Li, JG; Praticò, D | 1 |
| Cella, PS; da Silva, LECM; Deminice, R; Jordao, AA; Riberio, DF | 1 |
| Hussain, T; Kutala, VK; Lakshmitha, G; Naushad, SM; Nivetha, S; Rama Devi, AR; Stanley, AB | 1 |
| Chen, W; Guo, H; Han, X; He, M; Hu, H; Liang, Y; Miao, X; Tang, Y; Wang, F; Wang, J; Wang, Y; Wei, S; Wu, T; Yang, H; Yao, P; Yu, C; Yuan, J; Zhang, X; Zheng, D | 1 |
| Begum, R; Jadeja, SD; Mansuri, MS; Marfatia, YS; Patel, H; Singh, M | 1 |
| Chatterjee, M; Mukhopadhyay, K; Rajamma, U; Ray, A; Saha, T; Sinha, S; Verma, D | 1 |
| Chiua, YC; Hsieh, PL; Hung, CH; Jou, IM; Ma, CH; Tsai, KL; Tu, YK; Wu, CH | 1 |
| Cauli, O; Fuentes-Albero, M | 1 |
| Bhide, V; Mahalle, N; Naik, S | 1 |
| Hohberger, B; Jünemann, A; Rejdak, R | 1 |
| Guo, X; Inayat, A; Liu, K; Wu, J; Xuekelati, S; Yan, Z; Yang, X; Zhou, K | 1 |
| Azarpazhooh, MR; Bogiatzi, C; Mattia, A; Munoz, C; Quantz, MA; Spence, JD | 1 |
| Djuric, D; Jakovljevic, V; Jancic, S; Jeremic, J; Jeremic, N; Matic, S; Milosavljevic, I; Nikolic Turnic, T; Obrenovic, R; Rakocevic, M; Srejovic, I; Zivkovic, V | 1 |
| Bajic, V; Haidara, MA; Isenovic, ER; Jovanovic, M; Obradovic, M; Zaric, BL | 1 |
| Kim, H; Kim, J; Kwon, Y; Roh, H | 1 |
| Chen, Z; Dong, X; Liu, B; Qin, G | 1 |
| Hamano, T; Hayashi, K; Ikawa, M; Kanaan, NM; Kuriyama, M; Nakamoto, Y; Shirafuji, N; Yamamura, O; Yen, SH; Yoshida, H | 1 |
| Behera, J; George, AK; Kelly, KE; Mondal, NK; Richardson, KP; Tyagi, N | 1 |
| Colak, E; Dimitrijevic-Sreckovic, V; Gacic, J; Janeski, H; Janeski, N; Mrdovic, I; Soldatovic, I; Srećković, B; Sumarac-Dumanovic, M | 1 |
| Kontek, B; Olas, B; Oleszek, W; Stochmal, A | 1 |
| Abur, U; Avci, B; Gungor, L; Ozberk, MB; Polat, M | 1 |
| Kang, SS; Rosenson, RS | 1 |
| Garg, PR; Joshi, S; Saraswathy, KN; Yadav, S | 1 |
| Aniuliene, R; Bermagambetova, S; Gaiday, A; Tussupkaliyev, A | 1 |
| Chang, JY; Kuo, YS; Sun, A; Wang, YP; Wu, YC; Wu, YH | 1 |
| Brown, MJ; Chen, W; Cheng, H; Jin, H; Levy, MA; Sheng, X; Tian, J | 1 |
| Akrout, R; Ayedi, F; Bahloul, Z; Ben Hamad, M; Chaabane, S; Keskes, L; Maalej, A; Marzouk, S; Messedi, M; Rebai, A; Turki, M | 1 |
| Alfieri, DF; de Almeida, ERD; Dichi, I; Flauzino, T; Kaimen-Maciel, DR; Kallaur, AP; Lozovoy, MAB; Morimoto, HK; Oliveira, SR; Reiche, EMV; Sabino, BS; Simão, ANC | 1 |
| Fang, YY; Huo, JN; Li, D; Liu, HX; Ma, XX; Wang, TR; Wang, XX; Wu, QJ; Zhou, YM | 1 |
| Dhandapani, S; Goudihalli, S; Kumar, M; Mukherjee, K; Sandhir, R | 1 |
| Delgado-Saucedo, JI; Figuera, LE; Gallegos-Arreola, MP; Morán-Mendoza, A; Puebla-Pérez, AM; Rodríguez-Arévalo, F; Varela Almanza, KM; Zúñiga-González, GM | 1 |
| Lin, YY; Liu, XH; Liu, XY; Ma, XY; Xie, JC; Yu, J; Zhao, YC; Zhao, YX | 1 |
| Chen, M; Gao, X; Li, J | 1 |
| Ozcelik, F; Sertoglu, E | 1 |
| Chrysant, GS; Chrysant, SG | 1 |
| Adamkov, M; Kalenska, D; Kovalska, L; Kovalska, M; Lehotsky, J; Tatarkova, Z; Tomascova, A; Tothova, B | 1 |
| Blomhoff, R; Dhar, I; Midttun, Ø; Nygård, OK; Olsen, T; Pedersen, ER; Refsum, H; Svingen, GF; Tell, GS; Ueland, PM; Vinknes, KJ | 1 |
| Brizić, I; Čaušević, A; Jelić Knezović, N; Marković Boras, M; Mikulić, I; Vasilj, M | 1 |
| Chang, D; Hasegawa, H; Ichida, K; Inaba, N; Li, L; Liu, J; Yoshioka, W | 1 |
| Celik, E; Celik, SF | 1 |
| Bao, Z; Cheng, Y; Li, X; Wang, Z; Zhang, B; Zhang, Y; Zhong, X | 1 |
| Marumo, K; Saito, M | 2 |
| Bolevich, S; Jakovljevic, V; Joksimovic, J; Katanic, J; Mihailovic, V; Mijailovic, N; Nikolic, T; Pantic, M; Rosic, G; Selakovic, D; Zivkovic, V | 1 |
| Baloula, V; Fructuoso, M; Gueddouri, D; Janel, N; Kassis, N; Paul, JL | 1 |
| Anniwaer, J; Liu, MZ; Maimaiti, A; Xiamixiding, A; Xue, KD | 1 |
| Gaur, R; Kaur, G; Saraswathy, KN; Yadav, S | 1 |
| Gupta, P; John, D; John, SS; Rebekah, G | 1 |
| Shute, C | 1 |
| Benito, PJ; Carru, C; Díaz-Martínez, ÁE; González-Gross, M; González-Lamuño, D; Lopez-Torres, O; Maroto-Sánchez, B; Palacios, G; Valtueña, J; Zinellu, A | 1 |
| Guo, J; Li, Q; Ni, S; Wang, JZ; Yang, Y | 1 |
| George, AK; Homme, RP; Laha, A; Majumder, A; Singh, M; Tyagi, SC | 1 |
| Ke, CY; Lee, YJ; Lin, PK; Tien, N | 1 |
| Bian, R; Cao, G; Cooper, RS; Du Raza-Arvizu, R; Ji, P; Wang, W; Wang, Y; Xiong, Y; Xu, J; Zhu, J | 1 |
| Ostrakhovitch, EA; Tabibzadeh, S | 2 |
| Ban, Q; Chen, L; Cui, Y; He, M; Huang, X; Huo, Y; Li, J; Li, Y; Qin, X; Tang, G; Wang, B; Wu, H; Xu, X; Yin, D; Zhang, Y | 1 |
| Garg, PR; Ghosh, PK; Kaur, L; Saraswathy, KN | 1 |
| Huang, F; Ke, D; Liu, R; Mahaman, YAR; Salissou, MTM; Wang, JZ; Wang, Q; Wang, X; Wang, Y; Xu, Z; Zhang, B; Zhu, F | 1 |
| Jakubowski, H | 4 |
| Cohen, E; Goldberg, E; Krause, I; Margalit, I; Shochat, T | 1 |
| Guan, YF; Zhou, YF | 1 |
| Arslanova, AN; Dmitrieva, SA; Giniatullin, RA; Khaertdinov, NN; Minibayeva, FV; Sitdikova, GF; Yakovlev, AV; Yakovleva, OV; Ziganshina, AR; Ziyatdinova, GK | 1 |
| Geng, J; Li, X; Wang, L; Zhang, Y; Zhou, X | 1 |
| Aiello, P; Bello, C; Canali, R; Carminati, D; Comitato, R; Devirgiliis, C; Guantario, B; Meucci, A; Motta, V; Natella, F; Perozzi, G; Roselli, M; Tidona, F; Trevisi, P; Virgili, F; Zinno, P | 1 |
| Bermúdez-Muñoz, JM; Celaya, AM; Mandruzzato, G; Murillo-Cuesta, S; Pajares, MA; Partearroyo, T; Rodríguez-de la Rosa, L; Vallecillo, N; Varela-Moreiras, G; Varela-Nieto, I; Zeisel, SH | 1 |
| Chen, AF; Chen, R; Leng, Y; Ma, Y; Shi, R; Zeng, P; Zhang, Z | 1 |
| Chen, X; Hu, X; Xiao, S; Yang, C; Ye, R; Zhang, Z | 1 |
| Barroso, M; Castro, R; Esse, R; Tavares de Almeida, I | 1 |
| Capelli, I; Cappuccilli, M; Cianciolo, G; Gasperoni, L; La Manna, G; Tondolo, F; Zappulo, F | 1 |
| Baranovicova, E; Kalenska, D; Lehotsky, J; Tomascova, A | 1 |
| Arora, R; Bansal, AK; Bhattacharya, R; Hasan, T; Sharma, GS; Singh, LR | 1 |
| Abe, Y; Ao, M; Inoue, S; Inuiya, N; Kurose, S; Miyawaki, T; Niki, N; Ohta, J; Takaoka, H; Tanaka, K; Tanaka, S | 1 |
| Chen, S; Zhou, F | 1 |
| Cao, S; Fei, X; Luo, Z; Qin, B; Sui, X; Wang, F; Xin, Y; Xu, N; Yang, J; Yang, Z; Zhang, Y; Zhang, Z; Zhao, H; Zhao, X | 1 |
| Feng, Y; Jiang, Q; Luo, G; Wei, J; Xu, N; Yu, Y; Zhang, J; Zhang, X; Zheng, L | 1 |
| Allan, AM; Brigman, J; Jacobsen, DW; Jindal, A; Miller, JW; Paul, S; Poddar, R; Rajagopal, S; Winter, L | 1 |
| Alurkar, A; Basavaraj, A; Chandanwale, A; Harale, M; Kadam, DB | 1 |
| Aroonnual, A; Arthan, D; Chanchai, S; Chantaranipapong, Y; Chupeerach, C; Kaewprasert, S; Nakosiri, W; Nana, A; Paratthakonkun, C; Pooudoung, S; Prangthip, P; Soonthornworasiri, N; Tungtrongchitr, R; Wongsutthilerd, A | 1 |
| Liu, B; Wu, F; Yang, H | 1 |
| Anani Sarab, G; Kooshkaki, O; Kordi Tammandani, D; Zarfeshan Fard, Y | 1 |
| Baroni, L; Bazzerla, G; Bertola, C; Bonetto, C; Caberlotto, L; Rizzo, G | 1 |
| Alemdar, M; Selekler, HM | 1 |
| Chiang, CP; Sun, A; Wang, YP; Wu, YC; Wu, YH; Yu-Fong Chang, J | 1 |
| Jakubowski, H; Perła-Kaján, J | 2 |
| Kalinowska, S; Kłoda, K; Misiak, B; Safranow, K; Samochowiec, J; Trześniowska-Drukała, B | 1 |
| Wang, Q; Xu, B; Zhang, J; Zhao, K | 1 |
| Cannegieter, SC; Hensen, ADO; Lijfering, WM; Rosendaal, FR; van Hylckama Vlieg, A | 1 |
| Reddy, GB; Reddy, VS; Trinath, J | 1 |
| Chang, JY; Chiang, CP; Sun, A; Wang, YP; Wu, YC; Wu, YH | 2 |
| Diwaker, A; Kishore, D | 1 |
| Deng, J; Dong, H; Shen, Y; Xie, Z; Xiong, L; Zhang, P; Zhao, G | 1 |
| Charifa, A; El-Khoury, JM | 1 |
| Burkhanova, GF; Cmarko, L; Gaifullina, AS; Gerasimova, EV; Huang, J; Lazniewska, J; Rivas-Ramirez, P; Rzhepetskyy, Y; Sitdikova, GF; Tomin, A; Weiss, N; Zamponi, GW | 1 |
| Goyal, A; Gupta, JK; Narayan Yadav, H; Qureshi, SS | 1 |
| Aksamit, D; Drozdz, M; Ignacak, E; Janda, K; Kowalczyk-Michałek, M; Krzanowski, M; Sułowicz, W; Tabor-Ciepiela, B | 1 |
| Baghurst, PA; Coat, S; Gatford, KL; Hague, WM; Houda, CM; Lu, ZX; Owens, JA; Rowan, JA; Sikaris, K | 1 |
| Gao, W; Guo, C; Meng, B; Pu, L; Wei, J; Wu, J; Yang, J | 1 |
| Böttiger, AK; Farkas, SA; Finnell, RH; Isaksson, HS; Nilsson, TK; Ren, A | 1 |
| Feng, J; Jiang, C; Kong, W; Li, Y; Pang, Y; Wang, X; Xiang, X; Xu, G; Xu, M; Zhang, H | 1 |
| Beresford, SA; Brown, EC; Cheng, TY; Green, R; Miller, JW; Neuhouser, ML; Rodriguez, B; Song, X; Ulrich, CM; Zheng, Y | 1 |
| Belin, N; Bui, LC; Dairou, J; De Geest, B; de Koning, L; Delabar, JM; Dubois, T; Ducros, V; Jacobs, F; Janel, N; Mohamed, S; Paul, JL; Tlili, A | 1 |
| He, Z; Hu, Y; Huang, Y; Li, W; Wu, S; Wu, Y; Xu, D; Yang, Y; Zhong, J | 1 |
| Kalani, A; Kamat, PK; Tyagi, N; Tyagi, SC | 2 |
| Kalani, A; Tyagi, N; Tyagi, SC; Vacek, TP; Voor, MJ | 1 |
| Arslan, Z; Guler, A; Tavlasoglu, M; Yesil, FG | 1 |
| Briddon, A; Demiray, B; Duberley, K; Hargreaves, I; Land, J; Murphy, E; Turkes, F | 1 |
| Bogo, MR; Bonan, CD; Kolling, J; Loureiro, SO; Savio, LE; Scherer, EB; Schmitz, F; Schweinberger, BM; Siebert, C; Vuaden, FC; Wyse, AT | 1 |
| Bai, X; Feng, C; Hua, T; Huang, J; Liu, XY; Xu, Y | 1 |
| Garg, MK; Kulkarni, MV; Mahalle, N; Naik, SS | 1 |
| Gupta, S; Khandelwal, M; Manglani, K; Singh, RR; Surolia, A; Vijayan, V | 1 |
| Gao, X; Gong, J; Qian, L; Wang, W; Wang, X; Wu, S; Zhan, R; Zhang, Z; Zhao, Y | 1 |
| Caredda, E; Cennamo, M; Del Gado, R; Iossa, AC; Montaldo, L; Montaldo, P | 1 |
| Denecke, J | 1 |
| Douzis, ICh; Karkalousos, PL; Lazaris, AC; Liapi, CA; Mourouzis, IS; Pantos, CI; Perelas, AI; Strilakou, AA; Stylianaki, AT | 1 |
| Barman, SA; Bhalla, VK; Ganapathy, V; Newman, TM; Offermanns, S; Prasad, PD; Smith, SB; Sonne, SR; White, RE; Zhu, S | 1 |
| Ghosh, PK; Kaur, L; Mukhopadhhyay, R; Puri, M; Sachdeva, MP; Saraswathy, KN; Trivedi, SS; Walia, GK | 1 |
| Al Ali, M; Al Wadani, F; Khandekar, R; Ramzi, S; Salim, G | 1 |
| Collins, AR; Deary, IJ; Duthie, AC; Duthie, SJ; Lemmon, H; Murray, AD; Staff, RT; Starr, JM; Whalley, LJ | 1 |
| Fekih-Mrissa, N; Gritli, N; Klai, S; Mansour, M; Mrad, M; Mrissa, R; Nsiri, B | 1 |
| Flicker, L; Golledge, J; Hankey, GJ; McCaul, KA; Norman, PE; van Bockxmeer, FM; Wong, YY; Yeap, BB | 1 |
| Feng, W; Gui, L; Li, S; Wang, F; Wang, W; Wang, Y; Yang, L | 1 |
| De Geest, B; Gordts, SC; Jacobs, F; Muthuramu, I; Singh, N | 1 |
| Chrudinová, M; Demianová, Z; Jiráček, J; Kořínek, M; Mládková, J; Selicharová, I | 1 |
| Andria, G; Carnovale, E; Genovese, O; Giardina, B; Iacoviello, L; Mastroiacovo, P; Minucci, A; Mistura, L; Persichilli, S; Pounis, G; Ricci, R; Ruggeri, S; Scala, I; Turrini, A; Zappacosta, B | 1 |
| Bochud, M; Glaus, J; Lasserre, AM; Nabi, H; Preisig, M; Vollenweider, P; Waeber, G | 1 |
| Il'icheva, OE; Kharlamova, UV | 1 |
| Akioka, Y; Chikamoto, H; Hamatani, R; Hattori, M; Otsu, M | 1 |
| Cheng, DM; Huang, CY; Jiang, YG; Kong, HY; Liu, J; Pang, W; Sun, SD | 1 |
| Kałużna-Czaplińska, J; Michalska, M; Rynkowski, J; Żurawicz, E | 1 |
| Albright, KA; Neuman, JC; Schalinske, KL | 1 |
| Blanco-Vaca, F; Escolà-Gil, JC; Jauhiainen, M; Julve, J; Martín-Campos, JM; Osada, J; Quesada, H; Rentería-Obregón, IM; Rodríguez-Millán, E; Sánchez-Quesada, JL | 1 |
| Chen, DY; Chi, BJ; He, HL; Huang, WJ; Qin, WB; Wang, SQ | 1 |
| Imoto, I; Kinoshita, M; Numata, S; Ohmori, T; Shimodera, S; Tajima, A | 1 |
| Huang, J; Li, Y; Luo, M; Xie, N; Xu, H; Zheng, H | 1 |
| Balta, S; Cakar, M; Demirbas, S; Demirkol, S; Unlu, M | 1 |
| Bailey, KR; Garovic, VD; Kardia, SL; Kullo, IJ; Mosley, TH; Turner, ST; White, WM; Wiste, HJ | 1 |
| Gao, W; Guo, RC; Jia, Q; Liang, ES; Lin, WW; Liu, DS; Wang, SL; Zhang, JD; Zhang, WD | 1 |
| Hoey, L; McNulty, H; Pentieva, K; Strain, J; Ward, M | 1 |
| Chen, YJ; Duan, WY; Gong, XH; Huang, GY; Jiang, SS; Jin, L; Lu, CQ; Peng, QQ; Qiao, B; Shen, HB; Wang, HY; Zhao, JY | 1 |
| Dell'edera, D; Domenico, C; Epifania, AA; Francesco, L; Giuseppe, T; Malvasi, A; Marcello, G; Milazzo, GN; Pacella, E; Pierluigi, C; Tinelli, A | 1 |
| Fazeli, B; Ravari, H | 1 |
| Ayedi, F; Bahloul, Z; Chaabouni, Kh; Frigui, M; Jamoussi, K; Lahiyani, A; Messaouad, M; Messedi, M; Neifer, M; Turki, M | 1 |
| Cheng, YY; Hong, Y; Hou, Y; Li, YL; Niu, C; Yu, LX | 1 |
| Abbruzzese, G; Bandettini di Poggio, M; Barone, P; Bonuccelli, U; Borelli, P; Ceravolo, R; Contu, P; Cossu, G; Frosini, D; Iodice, R; Lopiano, L; Manca, D; Manganelli, F; Marchese, R; Melis, M; Mereu, A; Merola, A; Nicoletti, V; Paribello, A; Picillo, M; Santoro, L; Zibetti, M | 1 |
| Georgiades, A; Park, SB | 1 |
| Cao, L; Huang, X; Lou, X; Mou, N; Tan, H; Wu, W; Zou, Z | 1 |
| Tyagi, SC; Veeranki, S | 2 |
| Andras, A; Hansrani, M; Stansby, G | 1 |
| Chu, L; Dong, N; Wang, B; Xiao, L | 1 |
| Ferretti, A; Parisi, P; Villa, MP | 1 |
| El-Charabaty, E; El-Sayegh, S; Saifan, C | 1 |
| Liu, YP; Yang, YL | 1 |
| Digumarti, RR; Divyya, S; Gottumukkala, SR; Kotamraju, S; Kumaraswami, K; Kutala, VK; Naushad, SM; Reddy, CA | 1 |
| Ellis, SM; Melse-Boonstra, A; Moss, SJ; Nienaber-Rousseau, C; Towers, GW | 1 |
| Joseph, J; Loscalzo, J | 1 |
| Aizawa, T; Funase, Y; Ouchi, K; Sato, Y; Yamauchi, K | 1 |
| Sharma, PL; Sharma, S; Singh, M | 1 |
| Babhulkar, A; Bhide, V; Kulkarni, M; Mahalle, N; Naik, S; Parab, S; Thakre, R | 1 |
| Cui, W; Wen, X; Wu, W; Xu, E; Zhang, D; Zhang, Y | 1 |
| Ludwichowska, A; Szabat, K; Szadejko, K; Sławek, J | 1 |
| Cabarkapa, VS; Ilic, TA; Lozanov-Crvenkovic, ZS; Mitic, GP; Salatic, IR; Vuckovic, BA | 1 |
| Chlopocka-Wozniak, M; Dorszewska, J; Permoda-Osip, A; Rybakowski, JK; Skibinska, M | 1 |
| Hou, DD; Huang, HX; Li, X; Liu, T; Liu, W; Wang, K; Wang, W; Xu, HB; Xu, JP; Zhang, H; Zhao, Q; Zhen, PP | 1 |
| Li, X; Ling, W; Wang, M; Xia, M; Xiao, Y; Zhang, Y | 1 |
| Gupta, A; Kekunnaya, R; Mittal, V; Pathengay, A; Rao, BV; Sachdeva, V | 1 |
| Moraba, M; Motaung, S; Sengwayo, D | 1 |
| Köz, OG; Kural, G; Oner, V; Türkcü, FM; Yarangümeli, A | 1 |
| Ananthanarayanan, PH; Harichandrakumar, KT; Ikkruthi, S; Nandeesha, H; Rajappa, M; Satheesh, S; Sundar, I | 1 |
| Bartalini, S; Coppo, L; Di Giuseppe, D; Di Simplicio, P; Frosali, S; Margaritis, A; Priora, R; Summa, D; Ulivelli, M | 1 |
| Campion, J; Cordero, P; Martinez, JA; Milagro, FI | 1 |
| Chen, D; Chen, F; Guo, W; Hu, Y; Wei, Y; Wu, T; Xiong, J; Zuo, S | 1 |
| Chung, WY; Hwang, SC; Jung, YJ; Ki, SK; Kim, BT; Kim, K; Lee, KS; Lee, M; Oh, YM; Park, JH; Park, KJ; Park, SB; Sheen, S; Sun, JS | 1 |
| Subbotina, TF; Zhloba, AA | 1 |
| Iqbal, MP; Yakub, M | 2 |
| Kundu, S; Metreveli, N; Pushpakumar, SB; Sen, U | 1 |
| Akhlaghi, M; Davatchi, F; Faezi, ST; Faridar, A; Madanchi, N; Nadji, A; Sadeghi-Abdollahi, B; Shadmanfar, S; Shahram, F | 1 |
| Chao, MC; Davidson, LE; Hsu, HS; Hu, SL; Li, CI; Li, TC; Lin, CC; Lin, CH; Lin, WY; Liu, CS | 1 |
| Cosar, A; Gultepe, M; Muftuoglu, T; Ozcan, O | 1 |
| Cui, Y; Huo, Y; Jiang, S; Li, X; Liu, D; Liu, L; Liu, Z; Wang, Y; Xu, X; Zhao, Z | 1 |
| Diez-Roux, AV; Liu, Y; Nettleton, JA; Perng, W; Pilsner, JR; Shroff, MR; Villamor, E | 1 |
| Geerlings, MI; Kloppenborg, RP; Mali, WP; Nederkoorn, PJ; van der Graaf, Y; Vermeulen, M; Visseren, FL | 1 |
| Atamasirikul, K; Kajanachumpol, S; Tantibhedhyangkul, P | 1 |
| Jakubowski, H; Luczak, M; Marczak, L; Suszyńska-Zajczyk, J | 1 |
| Bahari, M; Jooyan, N; Karimi, M; Saffari, B; Senemar, S; Yavarian, M | 1 |
| Aydin, E; Karabacak, E; Muftuoglu, T; Ozcan, O | 1 |
| Ishii, I | 1 |
| Debreceni, B; Debreceni, L | 1 |
| Dhall, A; Garg, S; Gupta, SK; Kotwal, A; Kotwal, J | 2 |
| Caussé, E; Elbaz, M; Fakhry, A; Redonnet-Vernhet, I; Sabourdy, F | 1 |
| Dobrota, D; Drgova, A; Kovalska, M; Lehotsky, J; Mokra, D; Petras, M; Tatarkova, Z | 1 |
| Barbieri, L; Cassetti, E; De Luca, G; Di Giovine, G; Marino, P; Schaffer, A; Verdoia, M | 1 |
| Campana, C; Kobe, D; Peoples, K; Simon, E | 1 |
| Blom, H; Brouwer-Brolsma, EM; de Groot, LC; de Jongh, RT; Dhonukshe-Rutten, RA; Enneman, AW; Feskens, E; Geleijnse, JM; Ham, AH; Lips, P; Mattace-Raso, FU; Smulders, YM; Swart, KM; Uitterlinden, AG; van den Meiracker, AH; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Meurs, J; van Schoor, NM; van Wijngaarden, JP | 1 |
| Belarbi, S; Bendini, M; Chelouti, H; Djerdjouri, B; El Hadi Cherifi, M; Kacimi, G; Khelil, M; Nazef, K; Tazir, M | 1 |
| Fan, H; Gao, X; Liu, J; Wang, G; Xu, Y; Zhang, H | 1 |
| Díaz-Chamorro, A; Jiménez-Alonso, J; Martinez-Bordonado, J; Navarrete-Navarrete, N; Olvera-Porcel, C; Sabio, JM; Vargas-Hitos, JA; Zamora-Pasadas, M | 1 |
| Takagi, H; Umemoto, T | 1 |
| Chun, OK; Chung, SJ; Fernandez, ML; Koo, SI; McCullough, ML; Song, WO; Wang, Y | 1 |
| Li, MH; Tang, JP; Tang, XQ; Wang, CY; Wang, L; Wei, HJ; Xu, JH; Zhang, P; Zou, W | 1 |
| Christian, P; Khatry, SK; Schulze, KJ; Stewart, CP; West, KP; Yakub, M | 1 |
| Liu, H; Liu, T; Liu, X; Lu, L; Ma, L; Song, D; Sun, Q; Wang, K; Wang, W; Zhang, H; Zhang, X; Zhen, P; Zuo, X | 1 |
| Malone, FD | 1 |
| Dos Santos, TM; Kolling, J; Marques, EP; Scherer, EB; Siebert, C; Wyse, AT | 1 |
| Bahous, RH; Bedell, BJ; Caudill, MA; Deng, L; Grand'maison, M; Jadavji, NM; Malysheva, O; Rozen, R | 1 |
| Desai, AR; Gore, AD; Gore, MA; Rao, GS | 1 |
| Barbieri, L; Bellomo, G; Luca, GD; Marino, P; Niccoli, G; Perrone-Filardi, P; Schaffer, A; Suryapranata, H; Verdoia, M | 1 |
| Jiahong, X; Jinfa, J; Ruhui, L; Wenlin, M | 1 |
| Baszczuk, A; Kopczyński, Z | 1 |
| Aridogan, IA; Demir, E; Erken, U; Izol, V; Paydas, S; Tansug, Z | 1 |
| Jiang, X; Lavelle, M; Shi, C; Tan, H; Wang, H; Yang, X; Yu, C | 1 |
| Dong, N; Tang, X; Xu, B | 1 |
| Choi, ST; Kim, JS; Song, JS | 1 |
| Cheng, Y; Hua, X; Jiang, YD; Liang, Y; Ma, CJ; Ma, SC; Tian, J; Wang, J; Yang, AN; Yang, XL | 1 |
| Cheng, D; Huang, C; Jiang, Y; Kong, H; Lu, H; Pang, W; Yang, H | 1 |
| Armitage, J; Bennett, D; Clarke, R; Collins, R; Dangour, AD; de Groot, LC; Eussen, SJ; Galan, P; Grodstein, F; Halsey, J; Hankey, GJ; Lewerin, C; Lewington, S; Lonn, E; Parish, S; Skeaff, M; Spence, JD; Stott, DJ | 1 |
| Ashtiani, MN; Azimi, SZ; Kazemnezhad, E; Khosravi, M; Lebadi, M; Mirzajani, E; Monfared, A | 1 |
| Das, SK; Dhar, P; Hota, KB; Hota, SK; Kumar, A; Mahapatra, BB; Norboo, T; Sharma, VK; Srivastava, RB; Vashishtha, V | 1 |
| Apergis, G; Dimitriadis, G; Fotiou, P; Raptis, A; Theodossiadis, P; Vergados, I | 1 |
| Enomoto, D; Higaki, J; Irita, J; Kudo, K; Kukida, M; Miyoshi, K; Nagao, T; Okura, T; Pei, Z; Tanino, A | 1 |
| Feng, L; Han, C; Li, M; Liu, J; Mao, J; Pang, X; Wang, S; Wu, D; Zhang, X; Zhao, J | 1 |
| Elasmi, M; Feki, M; Hadj-Taieb, S; Hammami, MB; Hsairi, M; Jemaa, R; Kaabachi, N; Kallel, A; Omar, S; Sanhaji, H | 1 |
| Chen, R; Hu, J; Liu, R; Liu, X; Tian, Q; Wang, JZ; Wang, P; Wang, Q; Wang, XC; Xia, Y; Zeng, K | 1 |
| Jeon, SB; Kang, DW; Kim, JS; Kwon, SU | 1 |
| Djuric, D; Hrnčić, D; Jakovljević, V; Macut, D; Obrenović, R; Petronijević, N; Puškaš, N; Rašić-Marković, A; Stanojlović, O; Stojković, T; Sušić, V; Velimirović, M | 1 |
| Li, JG; Praticò, D | 1 |
| Basu, A; Garvey, WT; Jenkins, AJ; Klein, RL; Lopes-Virella, MF; Lyons, TJ; Stoner, JA; Thorpe, SR | 1 |
| Khanduri, U; Kumar, J; Neogi, SS; Sharma, A; Thomas, M | 1 |
| Baronio, D; Castro, K; Gottfried, C; Klein, Lda S; Perry, IS; Riesgo, R | 1 |
| Sengupta, S | 1 |
| Cibor, D; Jurczyszyn, A; Mach, T; Owczarek, D; Sałapa, K | 1 |
| D'Almeida, V; de Rezende, MM | 1 |
| Hong, JM; Lee, JS; Lee, PH; Yong, SW; Yoon, JH | 1 |
| Ahluwalia, J; Das, R; Kaur, R; Kumar, RM; Talwar, KK | 1 |
| Whayne, TF | 1 |
| Bai, L; Chen, Y; Fan, J; Li, Y; Liu, E; Liu, R; Wang, Y; Zhao, S | 1 |
| Drgova, A; Kaplan, P; Kovalska, M; Lehotsky, J; Petras, M; Tothova, B | 1 |
| Bôle-Feysot, C; Coëffier, M; Derouiche, F; Naïmi, D | 1 |
| Arning, E; Blokhin, IO; Bottiglieri, T; Dayal, S; Erger, RA; Faraci, FM; Jensen, M; Lentz, SR; Stevens, JW | 1 |
| Chengfeng, S; Lei, W; Lingjia, Q; Rui, Z; Wei, L; Xinxing, W | 1 |
| Fang, YL; Guo, JH; Li, CX; Li, Y; Ma, LS; Meng, HX; Min, GW; Niu, XY; Sun, MZ; Wang, TD; Zhang, J; Zhang, W | 1 |
| Cao, LY; Ding, H; Fan, WJ; Gan, HZ; Mei, Q; Xu, JM | 1 |
| Aliustaoglu, M; Bilici, A; Ercan, S; Gumus, M; Orcun, A; Seker, M; Sonkaya, A; Ustaalioglu, BB | 1 |
| Sun, NL; Yao, D | 1 |
| Cui, W; Liu, J; Sun, X; Xie, X; Zhang, D; Zhu, Y | 1 |
| Cediel, R; Garrido, F; Martínez-Álvarez, C; Martínez-Vega, R; Pajares, MA; Partearroyo, T; Varela-Moreiras, G; Varela-Nieto, I; Zeisel, SH | 1 |
| Chomtho, S; Iamopas, O; Ratanachu-ek, S | 1 |
| Bakoyiannis, C; Bastounis, E; Georgopoulos, S; Karaolanis, G; Moris, D; Palla, V; Skrapari, I | 1 |
| Brouwer-Brolsma, EM; Brug, J; de Groot, LC; Dhonukshe-Rutten, RA; Enneman, AW; Ham, AC; Lips, P; Sohl, E; Swart, KM; Uitterlinden, AG; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Meurs, JB; van Schoor, NM; van Wijngaarden, JP; Zillikens, MC | 1 |
| Heil, SG; Mandaviya, PR; Stolk, L | 1 |
| Cohen, E; Garty, M; Goldberg, E; Krause, I; Levi, A; Levi, M | 1 |
| Comparotto, H; Deminice, R; Jordao, AA | 1 |
| Capobianco, F; Catena, C; Colussi, G; Nait, F; Sechi, LA | 1 |
| Aliani, M; House, JD; Mayengbam, S; Raposo, S | 1 |
| Hlushchenko, SV; Zviagintseva, TD | 1 |
| Abbasian, S; Abdi, K; Babaei, M; Dashti, N; Gerayeshnejad, S; Lamei, N; Nazari, F | 1 |
| Fan, S; Sun, G; Wang, Y; Yang, B; Zheng, Q; Zhi, X | 1 |
| Alam, SF; Ganguly, P | 1 |
| Baracos, VE; Keshteli, AH; Madsen, KL | 1 |
| Gao, B; Ji, QH; Liu, XD; Liu, ZR; Ma, YY; Shi, M; Sun, D; Wang, B; Xu, X; Zhao, G | 1 |
| Choi, HS; Choi, YJ; Kim, SK; Kwak, HC; Lee, BH; Sim, WC; Yin, HQ | 1 |
| Garrard, P; Jacoby, R | 1 |
| de Jager, CA; Refsum, H; Rosenberg, IH; Smith, AD | 1 |
| Bennett, D; Clarke, R; Parish, S | 1 |
| Cohen, E; Garty, M; Goldberg, E; Krause, I; Levi, A; Vecht-Lifshitz, SE | 1 |
| Baggott, JE; Tamura, T | 1 |
| Cavallaro, RA; Desiderio, C; Di Napoli, A; Fuso, A; Gervasoni, J; Giardina, B; Nicolia, V; Persichilli, S; Scarpa, S | 1 |
| da Costa, KA; Fiorucci, S; Goedken, MJ; Guo, G; Jaeschke, H; Kong, B; Lebofsky, M; Lee, S; Orena, SJ; Renga, B; Rudraiah, S; Smalling, R; Tsuchiya, H; Wang, L; Yang, Z; Zeisel, SH; Zhang, Y | 1 |
| Birkner, E; Dobrakowski, M; Kasperczyk, A; Kasperczyk, S; Pawlas, N; Romuk, E; Rykaczewska-Czerwińska, M | 1 |
| Karpenko, AA; Klevanets, IuE; Shilova, AN | 1 |
| Kesherwani, V; Mishra, PK; Nandi, SS; Shahshahan, HR; Sharawat, SK | 1 |
| Bora, HK; Kalita, J; Misra, UK; Murthy, RC; Singh, SK | 1 |
| Bamba, M; Hirota, T; Miyajima, A; Muto, T | 1 |
| Gurda, D; Handschuh, L; Jakubowski, H; Kotkowiak, W | 1 |
| Azzaretto, L; Campanati, A; Consales, V; Ganzetti, G; Giannoni, M; Giuliodori, K; Guanciarossa, F; Liberati, G; Offidani, A; Postacchini, V; Vichi, S | 1 |
| Alam, MT; Kanpurwala, MA; Khan, MS; Sadiq, M | 1 |
| Phonrat, B; Satitvipawee, P; Suriyaprom, K; Tungtrongchitr, A; Tungtrongchitr, R | 1 |
| Ambrosino, P; Di Minno, A; Di Minno, MN; Lupoli, R; Lupoli, V; Marrone, E; Mitidieri, E; Nardo, A; Scaravilli, A; Tufano, A | 1 |
| Amin, R; De Geest, B; Debasse, M; Jacobs, F; Muthuramu, I; Nefyodova, E; Singh, N; Van Horenbeeck, I | 1 |
| Cao, CJ; Jiang, YD; Jiao, Y; Kong, FQ; Liu, XM; Yang, AN; Yang, XL; Zhao, L | 1 |
| Reimann, M; Weiss, N; Ziemssen, T | 1 |
| Reimann, M; Rüdiger, H; Weiss, N; Ziemssen, T | 1 |
| Luft, FC | 1 |
| Bian, ZX; Chen, ZY; Huang, Y; Ping Leung, F; San Cheang, W; Tak Wong, W; Wai Lau, C; Yen Tam, Y; Yu Tian, X; Yuen Ngai, C; Zhang, Y | 1 |
| Chan, SH; Chu, PM; Hung, CH; Tsai, KL | 1 |
| Ding, Y; Guo, H; Guo, S; He, J; Li, S; Liu, J; Ma, R; Niu, Q; Pang, H; Rui, D; Yan, Y; Zhang, J; Zhang, M | 1 |
| Han, F; Huang, Z; Liu, Y; Lu, J; Sugiyama, K; Sun, L; Wang, Q | 1 |
| Pawlak, R | 1 |
| Amoretti, A; Baldini, S; Corradini, R; Di Lorenzo, R; Ferri, P; Landi, G; Pollutri, G; Soli, M | 1 |
| Bonetti, F; Brombo, G; Magon, S; Zuliani, G | 1 |
| Sharma, M; Tiwari, M; Tiwari, RK | 1 |
| Cao, YJ; Cheng, J; Du, HP; Hu, LF; Li, JJ; Li, Q; Liu, CF; Wang, F; Wang, YL; Xu, XS; You, SJ | 1 |
| Hiramatsu, M; Kinoshita, S; Kunisawa, K; Nagao, M; Nakashima, N; Nomura, T | 1 |
| Bloemenkamp, KW; Blom, HJ; De Groot, CJ; Franx, A; Heijboer, AC; Hermes, W; Koopmans, C; Mol, BW; Van Pampus, MG; Visser, S | 1 |
| de la Cruz, AP; Del Pozo, EP; Florea, D; Molina-López, J; Quintero-Osso, B; Rodríguez-Elvira, M | 1 |
| Ghaznavi, H; Samiei, S; Soheili, Z; Soltanpour, MS | 2 |
| Fujita, A; Kanouchi, H; Miyazaki, Y; Sugimoto, Y | 1 |
| Baudin, B; Chalghoum, A; Dandana, A; Ferchichi, S; Jeridi, G; Karkouch, I; Miled, A; Noichri, Y | 1 |
| Li, Y; Liu, J; Pang, X; Zhang, X; Zhao, J | 1 |
| Asmer, I; Barak, M; Cassel, A; Flugelman, MY; Karkabi, B; Karkabi, K; Remer, E; Rozenberg, O; Shiran, A; Zittan, E | 1 |
| Chen, S; Guo, X; Hu, W; Li, W; Li, Z; Sun, G; Sun, Y; Wang, J; Yang, H; Yu, S; Zheng, L; Zhou, L | 1 |
| Tsuda, K | 1 |
| Kan, MY; Lai, WK | 1 |
| Battastini, AM; Bergamin, LS; Coutinho-Silva, R; de Souza Wyse, AT; Morrone, FB; Zanin, RF | 1 |
| Borah, A; Paul, R | 1 |
| Bodis, M; Geisel, J; Herrmann, M; Herrmann, W; Hübner, U; Kirsch, SH; Laufs, U; Pusceddu, I; Wagenpfeil, S; Werner, C | 1 |
| Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Liu, X; Parvez, F; Peters, BA; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Ajith, TA | 1 |
| Catena, C; Colussi, G; Sechi, LA | 1 |
| Bhatia, P; Singh, N | 1 |
| Antonini, G; Busetto, GM; Conti, SL; De Berardinis, E; De Cobelli, O; Del Giudice, F; Ferro, M; Gentile, V; Giovannone, R; Lucarelli, G; Ragonesi, G; Tricarico, S | 1 |
| Hsu, YH; Jiang, S; Li, K; Liu, Y; Tang, G; Venners, SA; Wang, B; Weinstock, J; Xu, X | 1 |
| Bonaterra, G; Dugi, KA; Edler, L; Hildebrandt, W; Kinscherf, R; Sauer, R | 1 |
| Bain, VG; Bhanji, RA; Ma, M; Montano-Loza, AJ | 1 |
| Chen, CH; Hsiao, YH; Huang, SC; Huang, YC; Yang, WC | 1 |
| Hajjari, S; Hemmateenejad, B; Javadi, S; Masoudi, R; Yousefi, R | 1 |
| Deng, G; Fang, P; Guo, J; Hou, F; Huo, Y; Li, Y; Qin, X; Tang, G; Wang, B; Wang, H; Wang, Q; Wang, X; Wu, S; Xie, D; Xu, X; Yang, S; Yuan, Y; Zhang, Q | 1 |
| Caussé, E; Fourcade, J; Fournier, P; Galinier, M; Roncalli, J; Salvayre, R | 1 |
| Achour, A; Achour, O; Bouacida, L; Boumaiza, I; Bouslama, A; Elmtaoua, S; Moussa, A; Omezzine, A; Rejeb, J; Rejeb, NB; Zellama, D | 1 |
| Balsat, M; Bert, A; Blond, E; Drai, J; Escoffre-Barbe, M; Etienne, G; Etienne, M; Fossard, G; Giraudier, S; Heiblig, M; Labussière-Wallet, H; Lega, JC; Mahon, FX; Morisset, S; Nicolini, FE; Redonnet-Vernhet, I; Sobh, M | 1 |
| Hu, S; Li, W; Liu, L; Ren, L; Wang, Y; Zhang, R; Zhao, X | 1 |
| Arru, D; Carru, C; Cossu, A; Giordo, R; Mangoni, AA; Pintus, G; Posadino, AM; Scanu, B; Sotgia, S; Zinellu, A | 1 |
| Hainsworth, AH; Weekman, EM; Wilcock, DM; Yeo, NE | 1 |
| Kolling, J; Longoni, A; Loureiro, S; Petenuzzo, L; Scherer, EB; Siebert, C; Weis, S; Wyse, AT | 1 |
| Cheng, WW; He, BW; Xu, X; Yang, WJ; Yang, XY | 1 |
| Cha, KS; Jeong, DW; Kang, YH; Kim, YJ; Lee, JG; Lee, SY; Song, SH; Tak, YJ | 1 |
| Cybulska, B; Kłosiewicz-Latoszek, L | 1 |
| Yamauchi, M | 1 |
| Allen, RH; Gaustadnes, M; Hvas, AM; Mudd, SH; Stabler, SP; Sørensen, JT | 1 |
| Bonatti, S; Bruzzese, L; Cuisset, T; Deharo, P; Fenouillet, E; Fromonot, J; Guieu, R; Mottola, G; Quilici, J; Ruf, J | 1 |
| Adamkov, M; Kovalska, L; Kovalska, M; Lehotsky, J; Mahmood, S; Tothova, B | 1 |
| Blom, HJ; de Groot, LC; de Jonge, R; de Jongh, RT; Dhonukshe-Rutten, RA; Enneman, AW; Feskens, EJ; Geleijnse, JM; Ham, AC; Lips, P; Mattace-Raso, FU; Smulders, YM; Swart, KM; Uitterlinden, AG; van den Meiracker, TH; van der Velde, N; van Dijk, SC; van Schoor, NM; van Wijngaarden, JP | 1 |
| Abbondanza, S; Davin, A; Guaita, A; Mangieri, M; Polito, L; Poloni, TE; Vaccaro, R; Villani, S | 1 |
| Ren, MY; Zhang, CS; Zhang, XJ; Zhong, JQ | 1 |
| Ansari, Z | 1 |
| Guo, W; Hu, YH; Jia, SH; Jia, X; Li, Y; Liu, J; Song, YX; Wei, YQ; Xiong, J; Zhang, T; Zuo, SW | 1 |
| Barbieri, L; Cassetti, E; De Luca, G; Schaffer, A; Suryapranata, H; Verdoia, M | 1 |
| Fang, X; Gu, X; Guan, S; Hua, Y; Ji, X; Liu, B; Liu, H; Tang, Z; Wang, C; Wu, X; Zhang, Z | 1 |
| Chen, Z; Jia, F; Lu, G; Sun, J; Wu, C | 1 |
| Bartalini, S; Cerase, A; Coppo, L; Di Giuseppe, D; Di Simplicio, P; Frosali, S; Margaritis, A; Martini, G; Priora, R; Summa, D; Ulivelli, M | 1 |
| Biniaz, V; Ebadi, A; Einollahi, B; Rahimi, A; Savari, S; Shermeh, MS; Tayebi, A | 1 |
| Badiga, S; Johanning, GL; Macaluso, M; Piyathilake, CJ; Siddiqui, NR | 1 |
| Gang, L; Yanyan, Z | 1 |
| Lin, L; Wang, B; Zhao, C | 1 |
| Bruzzese, L; Condo, J; Deharo, P; Durand-Gorde, JM; Fenouillet, E; Fromonot, J; Guieu, R; Kipson, N; Mottola, G; Ruf, J | 1 |
| Cuoghi, C; Fiorini, M; Marcacci, M; Marchini, S; Pietrangelo, A; Ventura, P; Venturelli, G | 1 |
| Cakmak, S; Cumhur Cure, M; Cure, E; Kirbas, A; Kirbas, S; Tufekci, A; Yazici, T | 1 |
| Demarquet, L; Feigerlova, E; Guéant, JL | 1 |
| Frydecka, D; Kiejna, A; Loska, O; Misiak, B; Piotrowski, P; Ślęzak, R; Szmida, E; Słoka, NK; Łaczmański, Ł | 1 |
| Mendioroz Iriarte, M; Muruzabal Pérez, J; Pulido Fontes, L; Pulido Fontes, M; Quesada Jiménez, P | 1 |
| Arnone, G; Coveri, M; Forti, P; Maioli, F; Pirazzoli, GL; Procaccianti, G; Zoli, M | 1 |
| Abbate, R; Boddi, M; Cioni, G; Gensini, GF; Giglioli, C; Gori, AM; Marcucci, R; Valente, S | 1 |
| Fang, L; He, C; Li, H; Li, X; Liu, N; Sun, X; Wang, J; Yang, Z | 1 |
| Abais, JM; Boini, K; Li, G; Li, PL; Ritter, JK; Xia, M | 1 |
| Andreau, K; Blanc, E; Bokobza, C; Daubigney, F; Delabar, JM; Janel, N; Legrand, B; Mortreux, M; Paul, JL; Renon, M; Rouach, H | 1 |
| Chen, KJ; Chen, RC; Lee, MS; Li, D; Wahlqvist, ML; Xiu, L | 1 |
| Benazzoug, Y; Janel, N; Latour, A; Middendorp, S; Otman, A; Yefsah-Idres, A | 1 |
| Cass, A; Gallagher, MP; Jardine, MJ; Kang, A; Kulshrestha, S; Navaneethan, SD; Nigwekar, SU; Perkovic, V; Strippoli, GF; Zoungas, S | 1 |
| Chen, S; Chen, Y; Guo, X; Qian, H; Sun, G; Sun, Y; Zhang, N | 1 |
| Cao, LD; Guo, G; Wu, QY; Xu, S | 1 |
| Gandhapudi, SK; Tyagi, SC; Veeranki, S | 1 |
| Refsum, H; Smith, AD | 1 |
| Li, Y; Lou, T; Ma, X; Peng, H; Wang, C; Ye, Z; Zhang, J; Zhang, Q | 2 |
| Gao, X; Liu, J; Miao, L; Wang, G; Xu, Y; Yang, N; Yao, Z | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Comoglu, SS; Guven, H; Kocer, B | 1 |
| Adaikalakoteswari, A; Maheswaran, H; Saravanan, P; Sukumar, N; Venkataraman, H | 1 |
| Jakubowski, H; Malinowska, A; Perła-Kajan, J; Rusek, M; Sitkiewicz, E; Utyro, O | 1 |
| Ding, R; Jiang, LJ; Jiang, Y; Lin, XQ; Shao, XX; Wu, H; Wu, XL; Xia, XP; Zheng, SZ | 1 |
| Jiang, T; Ou, Z; Shi, JQ; Tian, YY; Wang, BR; Zhang, YD; Zhao, HD; Zhou, JS | 1 |
| Drid, P; Ostojic, J; Ostojic, SM; Vranes, M | 1 |
| Dai, S; Deth, RC; Handy, DE; Loscalzo, J; Ma, J; Pottenplackel, LP; Zang, T; Zhou, ZS | 1 |
| Hua, P; Li, T; Liu, B; Liu, N; Shi, Y; Tian, X; Yan, Y | 1 |
| Andini, R; De Vincentiis, L; Dialetto, G; Durante-Mangoni, E; Iossa, D; Mattucci, I; Molaro, R; Parrella, A; Ursi, MP; Utili, R | 1 |
| Grzanka, A; Gwóźdź, A; Kasperska-Zając, A; Mazur, B; Zamłyński, J | 1 |
| Aggarwal, D; Bala, J; Kharb, S; Nanda, S | 1 |
| Wee, AK | 1 |
| Červeňová, T; Drgová, A; Halašová, E; Lehotský, J; Mahmood, S; Škovierová, H; Sopková, J; Vidomanová, E | 1 |
| Bamonti, F; Chiarelli, G; Consonni, D; De Giuseppe, R; De Vita, C; Dellanoce, C; Esposito, S; Guez, S; Maiavacca, R; Manzoni, F; Salera, S; Venturelli, G | 1 |
| George, AK; Kamat, PK; Mallonee, CJ; Tyagi, N; Tyagi, SC | 1 |
| Kong, X; Ma, X; Su, H; Xu, D; Zhang, C | 1 |
| Chen, D; Fang, K; Gao, P; Hu, Y; Li, J; Liu, K; Qin, X; Song, J; Sun, K; Tang, X; Wang, L; Wang, X; Wu, T; Wu, Y | 1 |
| Bala, J; Behera, J; Nuru, M; Tyagi, N; Tyagi, SC | 1 |
| Gluszek, J; Oszkinis, G; Pawlak, AL; Radziemski, A; Strauss, E; Supinski, W | 1 |
| Fu, Y; Liang, K; Su, Z; Sun, Y; Tang, W; Wang, X; Wang, Z; Wei, X; Yi, F; Zhang, Y; Zhou, M | 1 |
| Barrero, C; Gupta, S; Kruger, WD; Li, JG; Merali, S; Praticò, D | 1 |
| Arun Reddy, R; Dinesh Kumar, B; Diwan, PV; Hemanth Kumar, B; Mahesh Kumar, J | 1 |
| Deng, J; Feng, J; Jiang, C; Liu, B; Liu, H; Lü, S; Wang, X; Xu, Q | 1 |
| Astell-Burt, T; Chen, S; Duan, D; Duan, S; Feng, X; Gu, K; Han, L; Liu, Y; Lu, N; Ma, J; Tang, L; Wang, C; Wang, K; Wen, Q; Xu, G; You, D; Zhang, L; Zhang, T | 1 |
| Anning, Y; Guizhong, L; Li, Z; Nan, L; Ning, D; Shengchao, M; ShuQiang, L; Xiaoling, Y; Xiaoming, Y; Yideng, J; Yuexia, J | 1 |
| Spence, JD | 3 |
| Adachi, T; Kobayashi, Y; Ochi, A | 1 |
| Behera, J; Jeremic, N; Majumder, A; Tyagi, SC | 1 |
| Cui, W; Lou, J; Niu, N; Wang, F; Wang, Y; Wu, Y; Xu, D; Zhang, D; Zhang, L; Zhang, X | 1 |
| Nichols, J | 1 |
| Ingrosso, D; Perna, AF; Trepiccione, F; Zacchia, M | 1 |
| Abais-Battad, JM; Boini, KM; Conley, SM; Li, PL; Yuan, X; Zhang, Q | 1 |
| Hu, Z; Lei, W; Li, S; Long, Y; Nie, J; Zha, Y; Zhen, X; Zhu, F | 1 |
| Cheng, QZ; Dong, XF; Guo, QZ; Kong, FZ; Luo, WF; Shen, AR; Wu, DF; Wu, GH | 1 |
| Cheng, F; Dai, SX; Huang, JF; Li, GH; Li, WX; Liu, D; Liu, F; Lv, WW; Zhang, AJ; Zhang, H; Zhang, Q; Zhang, T; Zhou, T | 1 |
| Chen, J; Li, G; Lu, J; Peng, L; Shao, Y; Wang, Y; Xie, H; Xu, Z; Yuan, D; Zhang, C | 1 |
| Ma, Y; Wang, Y; Zhong, F; Zhuang, L | 1 |
| Dairou, J; Haddadi-Guemghar, H; Janel, N; Madani, K; Paul, JL; Tlili, A | 1 |
| Aixalá, M; Alberto, MF; Casais, P; Lazzari, MA; Meschengieser, SS; Salviú, MJ | 1 |
| Corella, D; Ferrando, F; Gómez, I; Mira, Y; Vayá, A | 1 |
| Frølich, W; Mansoor, MA; Stea, TH; Uglem, S; Wandel, M | 1 |
| Karasu, E; Sadan, G; Tasatargil, A | 1 |
| Dayal, S; Lentz, SR | 2 |
| Escola, JM; Garcia Gallego, F; Robles, NR; Sanchez Munoz-Torrero, JF; Velasco Gemio, J | 1 |
| Arning, E; Bottiglieri, T; Cooke, JP; Dayal, S; Faraci, FM; Kimoto, M; Lentz, SR; Murry, DJ; Rodionov, RN | 1 |
| Furusyo, N; Hayashi, J; Maeda, S; Ohnishi, H; Sawayama, Y; Tatsukawa, M | 1 |
| Atamasirikul, K; Kajanachumpol, S; Tantibhedhyangkul, P; Wilairat, P | 1 |
| Barone, P; Burn, DJ; Hsu, C; Lane, RM; Poewe, W; van Laar, T | 1 |
| Kalathil, D; Musarrat, K; Varughese, GI | 1 |
| Cheng, CH; Huang, MC; Huang, YC; Lee, BJ; Lin, PT; Tsai, TP | 1 |
| Fukada, S; Morita, T; Sugiyama, K | 1 |
| Morita, T; Ohuchi, S; Setoue, M; Sugiyama, K | 2 |
| Belkahla, R; Ben Abdelaziz, A; Ben Hadj Mbarek, I; Ben Rejeb, N; Boughzala, E; Bouslama, A; Kchok, K; Nabli, N; Omezzine, A; Rebhi, L; Rejeb, J; Slimane, N | 1 |
| Adeyomoye, AA; Awosanya, GO; Danesi, MA; Okubadejo, NU; Oladipo, OO | 1 |
| Huang, Y; Li, Z; Zhang, R; Zhi, Y | 1 |
| Ray, JG | 1 |
| Delabar, JM; Hamelet, J; Janel, N; Matulewicz, E; Noll, C; Paul, JL | 1 |
| Gulerman, C; Gungor, T; Kilic, S; Mollamahmutoglu, L; Pektas, M; Tonguc, E; Yilmaz, N | 1 |
| Guo, JX; Lu, CL; Wang, G | 1 |
| Berker, B; Cengiz, SD; Cesur, M; Demirtaş, S; Erdoğan, G; Kaya, C | 1 |
| Carrasco, M; Castro, C; Estrada, C; López-Toledano, MA; Murillo-Carretero, M; Rabaneda, LG; Ruiz, FA | 1 |
| Selhub, J | 3 |
| Smith, AD | 1 |
| Deshpande, SS; Hanumante, NM; Khadilkar, AV; Sanwalka, NJ; Vaidya, MV; Wadia, RS | 1 |
| Romanelli, P; Schwartzfarb, EM | 1 |
| Alam, MM; Ghani, U; Mohammad, AA; Schwindt, B; Shuaib, A; Shuaib, U; Todd, KG; Wang, C | 1 |
| Bulbul, T; Ferdausi, M; Hoque, MM; Islam, NA; Mahal, M | 1 |
| Klevay, LM | 1 |
| Shea, TB; Tchantchou, F | 1 |
| Ansari, MN; Bhandari, U | 1 |
| Cao, HF; Chen, QJ; Hao, P; Hu, CL; Qin, WB; Yang, YQ; Zhang, DS | 1 |
| Barro, C; Bosson, JL; Carpentier, P; Desruet, MD; Ducros, V; Pernod, G; Polack, B; Yver, J | 1 |
| Angelova, EA; Atanassova, PA; Chalakova, NT; Dimitrov, BD | 1 |
| Cao, XZ; Gao, SY; Li, SD; Zhang, KQ; Zhang, Y; Zhao, YS; Zou, CG | 1 |
| Barbakadze, T; Mikeladze, D; Zhuravliova, E | 1 |
| Davis, MR; Long, JN; Marques, M; Shell, DH | 1 |
| Antoniades, C; Bouras, G; Latsios, G; Marinou, K; Siasos, G; Stefanadi, E; Stefanadis, C; Tousoulis, D; Toutouzas, K; Vasiliadou, C | 1 |
| Bañes, I; Fridman, O; Gariglio, L; Junco, MN; Morales, A; Porcile, R; Potenzoni, MA; Vanasco, V | 1 |
| Cabarkapa, V; Ilincić, B; Stosić, Z; Zeravica, R | 1 |
| Devi, S; Joseph, J; Joseph, L; Kennedy, RH | 1 |
| Gupta, HP; Mehrotra, SS; Prasad, S; Shukla, M; Singh, R; Singh, RK; Singh, U | 1 |
| Chen, FP; Cheng, CH; Chou, MC; Huang, YC; Tsai, TP | 1 |
| Andreazza, AC; Erdtmann, B; Garcia, SC; Gonçalves, CA; Mackedanz, V; Matté, C; Moro, AM; Salvador, M; Scherer, EB; Stefanello, FM; Wyse, AT; Zanotto, C | 1 |
| Bai, CH; Chang, HY; Chen, HJ; Chen, KJ; Chuang, SY; Lin, BF; Pan, WH; Weng, LC; Yeh, WT | 1 |
| Lavie, CJ; Milani, RV | 1 |
| Li, N; Li, PL; Tang, L; Xia, M; Yi, F; Zhang, C | 1 |
| Chin-Dusting, J; De Silva, DA; Kingwell, B; Koh, TH; Moe, KT; Wong, MC; Wong, P; Woon, FP | 1 |
| Cho, CW; Park, CM; Rosenfeld, ME; Song, YS | 1 |
| Garcia, P; Herrmann, M; Herrmann, W; Hübner, U; Ross, S; Schorr, H; Taban-Shomal, O; Tami, A; Umanskaya, N; Wagner, A; Wildemann, B; Wolny, M | 1 |
| Matsumoto, Y; Morita, T; Ohuchi, S; Sugiyama, K | 2 |
| Albert, CM; Buring, JE; Cook, N; Grodstein, F; Kang, JH; Manson, J | 1 |
| Rosa, G; Uehara, SK | 1 |
| Choi, YM; Choue, R; Lim, HJ | 1 |
| Acharya, U; Carlsen, W; Gau, JT; Horvath, W; Hsueh, CT; Ventura, P | 1 |
| Hatzitolios, A; Ntaios, G; Savopoulos, C | 1 |
| Pessina, AC; Rossi, GP; Seccia, TM | 1 |
| Scholl, J | 1 |
| Govindaiah, V; Krishna, PC; Naushad, SM; Prabhakara, K; Radha Rama Devi, A | 1 |
| Caccamo, D; Currò, M; Gorgone, G; Ientile, R; Oteri, G; Parisi, G; Pisani, F; Pisani, LR; Rossini, PM | 1 |
| Garlassi, E; Guaraldi, G; Marchini, S; Moriondo, V; Nardini, G; Orlando, G; Squillace, N; Stentarelli, C; Tebas, P; Ventura, P; Zona, S | 1 |
| Cao, XZ; Gao, SY; Li, SD; Zhang, KQ; Zhang, M; Zhao, YS; Zou, CG | 1 |
| Kajdy, A; Niemiec, T | 1 |
| Clement, CI; Goldberg, I; Graham, SL; Healey, PR | 1 |
| Shevchenko, OP | 1 |
| Arutyunian, AV; Bulygina, ER; Kozina, LS; Makhro, AV; Mashkina, AP; Solenaya, OA; Trunova, OA | 1 |
| Baj, Z; Kaczmarek, P; Rysz, J; Sierakowska-Fijałek, A; Stepień, M | 1 |
| Bonadei, I; Dei Cas, L; Fiorina, C; Frattini, S; Raddino, R; Vizzardi, E; Zanini, G | 1 |
| Righetti, M | 2 |
| Armon, MP; Finglas, PM; Jennings, BA; Khandanpour, N; Loke, YK; Meyer, FJ; Willis, G; Wright, AJ | 1 |
| Arning, E; Banerjee, R; Bottiglieri, T; Hernandez, C; Li, S; Lin, JD; Liu, C; Vitvitsky, V | 1 |
| Banecka-Majkutewicz, Z; Banecki, B; Jakóbkiewicz-Banecka, J; Kadziński, L; Nyka, W; Sawuła, W; Wegrzyn, G | 1 |
| Bauer, DC; Cauley, J; Cummings, S; Jackson, R; Kooperberg, C; LaCroix, A; Leboff, MS; Lee, J; Lewis, C; Narweker, R; Thomas, AM; Wu, L | 1 |
| Baumgartner, RW; Benninger, DH; Georgiadis, D; Herrmann, FR; Kretschmer, R; Sarikaya, H; Schiller, A | 1 |
| Bansal, V; Kalita, J; Kumar, G; Misra, UK | 1 |
| de la Plata, CM; Diaz-Arrastia, R; Fields, BA; Gong, YH; Hynan, LS; Qu, BX; Rosenberg, RN; Weiner, MF; Womack, KB | 1 |
| Chryssogonidis, I; Destanis, E; Economou, I; Grekas, D; Hatzitolios, A; Karamitsos, D; Ntaios, G; Pidonia, I; Polatides, C; Savopoulos, C; Sion, M; Zebekakis, P | 1 |
| Arnolda, LF; Beer, C; Eikelboom, JW; Hankey, GJ; Lenzo, N; Potter, K | 1 |
| Cabrera, RM; Finnell, RH; Gupta, S; Jakubowski, H; Kraus, JP; Kruger, WD; Perla-Kaján, J; Shih, DM; Wang, H | 1 |
| Levasseur, R | 1 |
| Ballotta, A; Boncilli, A; Brozzi, S; Costa, E; Frigiola, A; Mehta, RH; Ranucci, M | 1 |
| Lonn, E; McQueen, M; Ray, JG; Saposnik, G; Sheridan, P | 1 |
| Achour, A; Kerkeni, M; Letaief, A; Maaroufi, K; Miled, A; Trivin, F | 1 |
| Fang, H; Huang, C; Jiang, Y; Kong, H | 1 |
| Phelip, JM; Roblin, X | 1 |
| Gurzhiĭ, AA; Papaian, LP; Saltykova, NB; Shmeleva, VM | 1 |
| Fan, DS; Gao, XH; Liu, N; Qiao, SD; Zhou, JW | 1 |
| Huang, L; Li, Y; Song, XM; Zhu, WL | 1 |
| Cheng, X; Luo, D; Song, Y; Yan, S | 1 |
| Borch, K; Eriksson, O; Nägga, K; Petersson, F; Redéen, S; Ryberg, A | 1 |
| Belcastro, V; Striano, P | 2 |
| Cutler, MJ; Freeman, DJ; House, AA; Spence, JD; Urquhart, BL | 1 |
| Collins, P; Cooney, MT; Daly, C; Fitzgerald, AP; Graham, IM; O'Callaghan, P | 1 |
| D'Angelo, A; Di Simone, S; Fimognari, FL; Loffredo, L; Monaldo, M; Pastorelli, R; Sampietro, F; Violi, F | 1 |
| Barchak, AG; Busanello, EN; Camargo, D; Carrion, MJ; da Costa, JC; Dalbem, A; de Mello Rieder, CR; de Sousa Miguel, SR; dos Santos, EF; Miglioranza, A; Rosa, C; Saute, J; Vargas, CR; Wajner, M; Zanatta, A | 1 |
| Couty, JP; Crain, AM; Delabar, JM; Hamelet, J; Janel, N; Noll, C; Paul, JL; Postic, C; Viguier, M | 1 |
| Acikel, S; Akdemir, R; Dogan, M | 1 |
| Anastos, K; Gao, W; Glesby, MJ; Hoover, DR; Kaplan, RC; Lee, I; Raiszadeh, F; Shi, Q | 1 |
| Altamura, C; Bressi, F; Chiovenda, P; Curcio, G; Gorgone, G; Ientile, R; Pisani, F; Rossini, PM; Silvestrini, M; Squitti, R; Tombini, M; Ursini, F; Vernieri, F | 1 |
| Lu, G; Wu, F; Xu, Z | 1 |
| Kawakami, Y; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
| Abruzzese, G; Antonini, A; Bonuccelli, U; Canesi, M; Cristina, S; Defazio, G; dell'Aquila, C; Lamberti, P; Livrea, P; Logroscino, G; Marchese, R; Pacchetti, C; Zagaglia, R; Zoccolella, S | 1 |
| Elmadfa, I; Singer, I | 1 |
| Dun, Y; Duplantier, J; Farley, MJ; Ganapathy, PS; Liu, K; Moister, B; Moister, TK; Mysona, BA; Prasad, PD; Roon, P; Smith, SB | 1 |
| Aguirre Errasti, C; Egurbide Arberas, MV; Martínez Berriotxoa, A | 1 |
| Agarwal, GG; Anand, P; Awasthi, S; Mahdi, A; Tiwari, M | 1 |
| Chang, YY; Lai, SL; Lan, MY; Liu, JS; Su, CS; Tseng, YL | 1 |
| Bhagwat, VR; Rathod, IM; Yadav, AS | 1 |
| Cao, Y; Chai, JG; Chen, YC; Liu, XD; Liu, XQ; Ma, C; Shao, JP; Zhao, J; Zhou, J | 1 |
| Basir, A; Bougteba, A; Kissani, N | 1 |
| Cirocchi, R; Farinella, E; La Mura, F; Sciannameo, F | 1 |
| Herrmann, W; Obeid, R | 2 |
| Abe, OA; Basu, P; Givvimani, S; Metreveli, N; Passmore, JC; Sen, U; Shah, KS; Tyagi, N; Tyagi, SC | 1 |
| Akgul, EO; Cakir, E; Cayci, T; Erbil, MK; Gocgeldi, E; Kunak, ZI; Kurt, YG; Macit, E; Yaman, H | 1 |
| Aridon, P; D'Amelio, M; Gueli, MC; Lupo, I; Mangiapane, P; Ragonese, P; Saia, V; Salemi, G | 1 |
| Handy, DE; Joseph, J; Loscalzo, J | 1 |
| Givvimani, S; Maldonado, C; Pushpakumar, S; Rosenberger, D; Soni, CV; Todnem, ND; Tyagi, SC; Villafane, J | 1 |
| Chi, J; Guo, H; Wang, P; Xing, Y | 1 |
| Adamopoulos, D; Cokkinos, D; Gialernios, T; Gymnopoulou, E; Karpanou, E; Kyvelou, SM; Stefanadis, C; Vyssoulis, G | 1 |
| Agrawal, S; Baburaj, VP; Sankhwar, SN; Sharma, RK; Tripathi, G | 1 |
| Beghi, E; Bendotti, C; Logroscino, G; Zoccolella, S | 1 |
| Jiménez-Escrig, A; Martín, A; Sánchez-Moreno, C | 1 |
| Armon, MP; Jennings, B; Khandanpour, N; Loke, YK; Meyer, FJ | 1 |
| Cruz, E; Terrados, N; Valcárcel, G; Venta, R | 1 |
| Kundu, S; Sen, U; Tyagi, N; Tyagi, SC | 1 |
| Eminagaoglu, S; Erem, C; Ersoz, HO; Hacihasanoglu, AB; Karahan, C; Kocak, M; Ukinc, K; Yilmaz, M | 1 |
| Cagnacci, A; Cannoletta, M; Volpe, A | 1 |
| Cunha, AA; Dos Santos, TM; Mackedanz, V; Matté, C; Netto, CA; Pereira, LO; Wyse, AT | 1 |
| Boreham, CA; Hammons, AL; McNulty, H; Mitchell, LE; Murray, L; Scott, JM; Strain, JJ; Summers, CM; Whitehead, AS; Woodside, JV; Young, IS | 1 |
| Chandler, DL; Granger, JP; LaMarca, B; Llinas, MT; Reckelhoff, JF; Speed, J | 1 |
| Saito, M | 1 |
| Boldyrev, AA | 1 |
| Grandone, E; Margaglione, M; Pisanelli, D; Tomaiuolo, M; Vecchione, G | 1 |
| Ates, K; Ertek, S; Torun, AN | 1 |
| O, K; Siow, YL; Wu, N | 1 |
| Bivona, G; Butera, D; Ciaccio, M; Fazzari, M; La Bella, V; Paladino, P; Piccoli, T; Valentino, F | 1 |
| de Andrade, CR; de Oliveira, AM; Eberlin, MN; Haddad, R; Iyomasa, MM; Ramalho, LN; Tirapelli, CR; Uyemura, SA | 1 |
| Avignon, A; Badiou, S; Bariolet, S; Cristol, JP; Dupuy, AM; Sultan, A | 1 |
| Kundu, S; Mishra, PK; Tyagi, N; Tyagi, SC | 1 |
| Gültepe, M; Ipçioğlu, OM; Kiralp, MZ; Ozçakar, L; Ozcan, O | 1 |
| Remko, M; Remková, A | 1 |
| Acca, M; D'Erasmo, E; Francucci, CM; Petramala, L | 1 |
| Atabak, S; Azadibakhsh, N; Golestan, B; Hosseini, RS; Nateghiyan, N; Rad, AH | 1 |
| Kordich, L; Lauricella, AM; Oberholzer, MV; Quintana, IL | 1 |
| Chang, HI; Chen, CN; Chen, HJ; Cheng, JC; Chien, S; Sung, ML; Wu, CC; Yen, CK | 1 |
| Ghafari, A; Masoumi, R; Moghaddasi, S; Nafisi, R; Nogh, H; Nouri-Majalan, N | 1 |
| Melo, SS; Vannucchi, H | 1 |
| Kuriyama, N; Mitani, S; Mizuno, T; Ozaki, E; Ozasa, K; Shigeta, M; Watanabe, Y; Yokota, S | 1 |
| Eshraghian, A; Izadi, HR; Naghshvar, F; Pourahmad, M; Shojaie, M | 1 |
| Assadi, M; Ebrahimi, A; Jafari, SM; Moradhaseli, F; Movahed, A; Nabipour, I; Obeidi, N; Sanjdideh, Z; Vahdat, K | 1 |
| Chen, CC; Hsieh, IC; Hsieh, MJ; Lee, CH; Lee, TH; Lin, FC; Wen, MS; Wu, D | 1 |
| Burlutsky, G; Flood, VM; Gopinath, B; Mitchell, P; Wang, JJ; Wong, TY | 1 |
| Blazícek, P; Krajcovicová-Kudlácková, M; Krivosíková, Z; Nĕmcová, T; Spustová, V; Stefíková, K; Valachovicová, M | 1 |
| Almeida, D; Broekman, MJ; Deora, AB; Greenberg, CB; Hajjar, KA; Jacovina, AT; Ling, Q; Marcus, AJ; Smith, JD | 1 |
| Duan, ZQ; Fan, YY; He, JA; Hu, XH; Liu, CW; Xin, SJ; Yang, DH; Yang, J; Zhang, J; Zhang, Q; Zhang, ZS | 1 |
| Gómez-Sánchez, MP; Melero-Rubio, E; Merchán-Mayado, E; Párraga-Díaz, M; Pellicer-Villaescusa, S | 1 |
| Bonadei, I; Dei Cas, L; Fiorina, C; Raddino, R; Vizzardi, E; Zanini, G | 1 |
| Chmurzynska, A; Malinowska, A | 1 |
| Chen, WS; Cheng, CH; Huang, YC; Tsai, TP | 1 |
| Thiengburanatham, S | 1 |
| Arvanitidou, M; Makedou, A; Malindretos, P; Papandreou, D; Rousso, I | 2 |
| Gould, TJ; Kruger, WD; Portugal, GS; Pratico, D; Wang, H; Zhuo, JM | 1 |
| Azizi, ZA; Dabaghmanesh, MH; Mohammadi, A; Namavar, MR; Omrani, GR; Omrani, L; Omrani, LR; Zamani, A | 1 |
| Akgul, A; Durmazlar, SP; Eskioglu, F | 1 |
| McNulty, H; Scott, JM; Strain, JJ; Ward, M; Wilson, CP | 1 |
| Grekas, D; Hatzitolios, A; Ntaios, G; Savopoulos, C | 1 |
| Brustolin, S; Félix, TM; Giugliani, R | 1 |
| Cardoso, JE; Carvalho, MG; Dusse, LM; Fernandes, AP; Lages, GF; Lasmar, MC; Lwaleed, BA; Novelli, BA; Soares, AL; Sousa, MO; Vieira, LM | 1 |
| Malinowska, J; Nowak, P; Olas, B | 2 |
| Dayal, S; DiBello, PM; Jacobsen, DW; Kaveti, S; Kinter, M; Lentz, SR; Zhang, D | 1 |
| Hu, Q; Huang, Y; Ma, L; Yu, X | 1 |
| Bottiglieri, T; Devlin, AM; Green, TJ; Innis, SM; Singh, R | 1 |
| Garg, G; Ghosh, S; Karthikeyan, G; Kumar, A; Kumar, J; Ramakrishnan, L; Sanapala, KR; Sengupta, S; Sundaramoorthy, E | 1 |
| Caccamo, D; Condello, S; Curro', M; Ferlazzo, N; Ientile, R; Pisani, F | 1 |
| Chun, S; Chung, SJ; Kim, BJ; Kim, GS; Kim, HK; Kim, MJ; Kim, SR; Koh, JM; Lee, MC; Lee, SH; Ryu, JS | 1 |
| Balakrishnan, V; Girish, BN; Rajesh, G; Rao, NA; Reshmi, S; Vaidyanathan, K | 1 |
| Belcastro, V; Calabresi, P; Castrioto, A; Gorgone, G; Ientile, R; Menichetti, C; Pierguidi, L; Pisani, F; Rossi, A; Tambasco, N | 1 |
| Jakovic, N; Jaksic, V; Knezevic, M; Markovic, V; Milenkovic, S; Stefanovic, I | 1 |
| Anees, M; Asghar, A; Ibrahim, M; Mumtaz, A; Shaheen, SM | 1 |
| Angeli, A; Borrione, P; Fagnani, F; Grasso, L; Pigozzi, F; Spaccamiglio, A; Termine, A | 1 |
| Devlin, AM; Green, TJ; Innis, SM; McMahon, JA; Skeaff, CM; Venn, BJ; Williams, SM | 1 |
| Altantsetseg, P; Erdenekhuu, N; Huang, SL; Mungun-Ulzii, K; Zulgerel, D | 1 |
| Almeida, OP; Fenner, S; Flicker, L; Ford, AH; Hegarty, S; Hirani, V; McCaul, K; van Bockxmeer, F | 1 |
| Komarov, AL; Panchenko, EP; Shakhmatova, OO | 1 |
| Alter, P; Figiel, JH; Klose, KJ; Maisch, B; Renz, H; Rominger, MB; Rupp, H | 1 |
| Antoniades, C; Bouras, G; Chatzis, G; Marinou, K; Miliou, A; Papageorgiou, N; Stefanadis, C; Tentolouris, C; Tousoulis, D; Tsioufis, C | 1 |
| Givvimani, S; Sen, U; Tyagi, N; Tyagi, SC; Vacek, JC | 1 |
| Doupis, J; Eleftheriadou, I; Gonis, A; Katsilambros, N; Kokkinos, A; Pavlatos, S; Perrea, D; Tentolouris, N | 1 |
| Allen, LH; Garrod, MG; Green, R; Haan, MN; Miller, JW | 1 |
| Bhat, DS; Deshmukh, US; Fall, CH; Hardikar, PS; Jackson, AA; Joglekar, CV; Konde, TB; Lubree, HG; Naik, SS; Nanivadekar, AS; Ramdas, LV; Raut, DA; Refsum, H; Wills, AK; Yajnik, CS | 1 |
| Bartegi, A; López, JJ; Redondo, PC; Rosado, JA; Salido, GM; Zbidi, H | 1 |
| Gargoum, R; Maldonado, C; Metreveli, N; Rosenberger, D; Sen, U; Tyagi, N; Tyagi, S | 1 |
| Akbari, MR; Gheisari, M; Kavand, S; Roodsari, MR; Saeedi, M; Sarrafi-rad, N | 1 |
| Gao, JJ; Liu, JM; Qu, QG | 1 |
| Garcia, P; Herrmann, M; Herrmann, W; Histing, T; Holstein, JH; Klein, M; Kurz, K; Menger, MD; Pohlemann, T; Siebel, T; Splett, C | 1 |
| Kaur, T; Pal Singh, A; Singh Bedi, PM; Singh, N; SinghDahiya, R | 1 |
| Coppola, A; Di Minno, G; Di Minno, MN; Lupoli, R; Tremoli, E | 1 |
| Adragna, NC | 1 |
| Choi, BY; Ha, HY; Kim, HJ; Kim, JU; Kim, MK | 1 |
| Mishra, PK; Sen, U; Tyagi, N; Tyagi, SC | 1 |
| Abe, O; Gargoum, R; Munjal, C; Qipshidze, N; Sen, U; Tyagi, SC | 1 |
| Hasdai, D; Iakobishvili, Z; Kaluski, DN; Lev, E; Mager, A; Messika, AH; Shohat, M | 1 |
| da Cunha, AA; Ferreira, AG; Wyse, AT | 1 |
| Dohi, Y; Ito, A; Itoh, T; Kajikuri, J; Koyama, K; Kumagai, H; Nakamura, H; Nishio, T; Ohte, N; Sano, A; Yamamoto, J | 1 |
| Fujiki, Y; Hirashima, Y; Kanouchi, H; Matsumoto, M; Nishiyama, K; Oka, T; Okabe, M; Seshimo, S | 1 |
| Adam, DJ; Bradbury, AW; Darvall, KA; Fegan, CD; Sam, RC; Silverman, SH | 1 |
| Francis, AM; Miller, JP; Nagele, P; Rao, LK; Wilcox, U | 1 |
| Akbulut, S; Altiparmak, E; Kucukazman, M; Ozaslan, E; Topal, F; Yonem, O | 1 |
| Jang, Y; Lee, M; Oh, H; Park, H; Park, M; Seo, H | 1 |
| Ansquer, JC; Brugère, L; Foucher, C | 1 |
| Aouni, Z; El Oudi, M; Machghoul, S; Mazigh, C; Ouertani, H | 1 |
| Arnal, C; Barranquero, C; Bregante, MA; García-Gimeno, MA; Gascón, S; Godino, J; Guillén, N; Guzmán, MA; Hernandez, E; Lou-Bonafonte, JM; Navarro, MA; Nuño-Ayala, M; Osada, J; Royo-Cañas, M; Sarría, AJ | 1 |
| Blom, HJ; Smulders, YM | 1 |
| Armitage, JM; Bowman, L; Bulbulia, R; Clarke, RJ; Collins, R; Haynes, R; Parish, S; Peto, R; Rahimi, K; Sleight, P; Wallendszus, K | 1 |
| Kołodziejczyk, J; Malinowska, J; Olas, B | 1 |
| Bhopal, RS; Rafnsson, SB; Saravanan, P; Yajnik, CS | 1 |
| Chen, Z; Ge, L; Huang, S; Jiang, T; Jiang, Y; Lei, Y; Xia, B; Zhao, J; Zhou, F | 1 |
| Wu, Y; Yang, L; Zhong, L | 1 |
| Dahiya, K; Dhankhar, R; Sachdeva, A; Sethi, J; Singh, SB; Singh, V; Sood, S; Yadav, M | 1 |
| Conrad, R; Geiser, F; Harbrecht, U; Imbierowicz, K; Klingmüller, D; Liedtke, R; Meier, C; Oldenburg, J | 1 |
| Dionisio, N; Jardín, I; Rosado, JA; Salido, GM | 1 |
| Dentali, F; La Regina, M; Orlandini, F; Prisco, D | 1 |
| Dwyer, J; Hibberd, P; Jacques, P; Leung, J; Rand, W; Rocco, MV | 1 |
| Oosterbaan, AM; Steegers-Theunissen, RP; van Mil, NH | 1 |
| Alves, T; Fonseca, A; Heimfarth, L; Loureiro, SO; Moura Neto, V; Pessoa-Pureur, R; Romão, L; Wyse, AT | 1 |
| Iliceto, G; Lamberti, P; Lamberti, SV; Logroscino, G; Santamato, A; Zoccolella, S | 1 |
| Cheng, DM; Huang, CY; Jiang, YG; Kong, HY; Pang, W; Yang, HP | 1 |
| Aggio, S; Chinaglia, M; Grassetto, G; L'Erario, R; Mazza, A; Montemurro, D; Pastore, G; Piergentili, C; Rubello, D; Zamboni, S; Zanier, A; Zanon, F | 1 |
| Li, L; Li, Q; Sun, J; Tan, HM; Wu, WK; Yan, TT; Zhang, Q; Zhang, XH | 1 |
| Aydoğdu, M; Bukan, N; Ekim, N; Kanbay, A; Köktürk, N; Özyılmaz, E | 1 |
| Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT | 1 |
| Grenz, A; Hammel, P; Hermes, M; Kloor, D; Osswald, H; Roll, JB | 1 |
| Bhat, D; Joglekar, C; Joshi, S; Katre, P; Lubree, H; Otiv, S; Rush, E; Yajnik, C | 1 |
| Atabati, E; Ostovan, MA; Raisjalai, GA; Roozbeh, J; Sagheb, MM; Sohrabi, Z | 1 |
| Chang, CC; Chang, WN; Chen, C; Chen, CF; Chen, NC; Huang, CW; Lin, YT; Lui, CC; Tu, MC; Wang, YL | 1 |
| Aminzadeh, MA; Gollapudi, P; Vaziri, ND | 1 |
| Afrasibi, AR; Akbari, A; Dehbozorgian, J; Gafari, H; Gerdabi, J; Karimi, M | 1 |
| Givvimani, S; Metreveli, N; Mishra, PK; Tyagi, SC | 1 |
| Chatzopoulos, S; Hatzitolios, A; Mikhailidis, D; Ntaios, G; Savopoulos, C | 1 |
| Chen, AF; Feng, J; He, L; Hong, T; Li, F; Liu, J; Liu, S; Mao, J; Wang, G; Wang, X; Yu, J; Zeng, H | 1 |
| Malinowska, J; Olas, B | 3 |
| Kapoor, P; Khanna, S; Pillai, KK; Vohora, D | 1 |
| Fedin, AI; Kaluga, AS; Mironova, OP; Solov'eva, EIu | 1 |
| Biter, HI; Cakar, MA; Cetin, S; Dinçkal, MH; Enhos, A; Okuyan, E; Onür, I; Sahin, I; Uslu, A | 1 |
| Adachi, K; Akatsu, H; Hosono, T; Jung, CG; Komano, H; Michikawa, M; Minagawa, H; Ohtsuka, C; Takahashi, S; Terayama, Y; Wakita, H; Watanabe, A | 1 |
| Finch, JM; Joseph, J | 1 |
| Antonakos, G; Armaganidis, A; Bagos, P; Dima, K; Dimopoulou, I; Kapsimali, V; Kopterides, P; Nikolopoulos, G; Travlou, A; Tsangaris, I; Tsantes, A; Vrioni, G | 1 |
| Benazzoug, Y; Cherifi, Mel H; Delabar, JM; Delcayre, C; Janel, N; Noll, C; Raaf, L; Samuel, JL | 1 |
| Braganza, JM; McCloy, RF; Odom, N; Ubbink, JB | 1 |
| Erdogan, M; Eroglu, Z; Karadeniz, M; Olukman, M; Saygili, F; Tamsel, S; Yilmaz, C; Zengi, A | 1 |
| Ebbing, M; Ueland, PM | 1 |
| Cao, SG; Huang, S; Jiang, Y; Lei, Y; Lin, LM; Wang, CG; Xia, B; Xu, CL; Zhao, J | 1 |
| Acilmis, YG; Balat, O; Cebesoy, FB; Cicek, H; Dikensoy, E; Kutlar, AI; Ozturk, E; Pence, S | 1 |
| Bonet, E; Carrasco, P; Morales-Suárez-Varela, MM; Plumé, G; Vayá, A | 1 |
| Falcone, JC; Givvimani, S; Munjal, C; Qipshidze, N; Tyagi, N; Tyagi, SC | 1 |
| da Cunha, AA; da Cunha, MJ; Kolling, J; Scherer, EB; Wyse, AT | 1 |
| Carvalho, MG; das C L E Silva, F; Faria, MC; Fernandes, AP; Freitas, FR; Gomes, KB; Mota, AP; Santos, ME | 1 |
| Steed, MM; Tyagi, SC | 1 |
| Farkas, M; Ineichen, B; Jelcic, I; Jung, H; Keskitalo, S; Kühnlein, P; Linnebank, M; Ludolph, AC; Petersen, J; Semmler, A; Weller, M | 1 |
| Collins, P; Cooney, MT; Graham, IM; Mayne, P; McGarrigle, SA; Monavari, A; Moran, N; O'Neill, S; Walsh, GM | 1 |
| Abraham, JM; Cho, L | 1 |
| Wu, SQ; Xu, D; Yi, D | 1 |
| Mayers, M; Moradi, IE; Rosenbaum, PS; Srinivasan, S; Zelefsky, JR | 1 |
| Agam, G; Belmaker, R; Bromberg, A; Levine, J | 1 |
| O, K; Sarna, LK; Siow, YL; Wu, N | 1 |
| Abbate, R; Fedi, S; Giambene, B; Marcucci, R; Menchini, U; Prisco, D; Sodi, A; Sofi, F | 1 |
| Eijkemans, MJ; Laven, JS; Lindemans, J; Smedts, HP; Steegers, EA; Steegers-Theunissen, RP; Valkenburg, O; van Uitert, EM | 1 |
| Choi, KC; Kwok, T; Lam, LC; Law, CB; Lee, J; Pan, PC; Yung, CY | 1 |
| Blom, HJ; Fowler, B; Kožich, V | 1 |
| Cacciapuoti, F | 2 |
| da Cunha, AA; Ferreira, AG; Machado, FR; Mussulini, BH; Tagliari, B; Wofchuk, S; Wyse, AT | 1 |
| Duan, JH; Hong, N; Hou, DD; Wang, HX; Wang, W; Zhao, Q; Zhen, HX; Zhen, PP | 1 |
| Agoston-Coldea, L; Dumitrascu, DL; Gatfosse, M; Lupu, S; Mocan, T | 1 |
| Rosenblatt, DS; Watkins, D | 1 |
| Andrikopoulos, V; Barbatis, C; Bastounis, E; Drougou, A; Georgopoulos, S; Klonaris, C; Koliaraki, V; Lioupis, C; Mamalaki, A | 1 |
| Hoffman, M; Sauls, DL; Warren, M | 1 |
| Corella, D; Ejarque, I; Laiz, B; Tembl, J; Vayá, A | 1 |
| Badia, N; Carmona, P; Corella, D; Hernandez Mijares, A; Pérez, R; Vayá, A | 1 |
| Fleming, JT; Tyagi, N; Tyagi, SC; Vacek, JC; Vacek, TP | 1 |
| Chen, JR; Chen, YL; Hsieh, YC; Peng, HC; Yang, SC; Yang, SS | 1 |
| Bengel, G; Ebersbach, G; Ehret, R; Jugel, C; Klostermann, F; Muhlack, S; Müller, T | 1 |
| Ghorbani, R; Jamshidi, L; Malek, F; Malek, M; Soliemani, A; Tamadon, MR | 1 |
| Ahmad, M; Bibi, S; Memon, A; Qazi, RA; Qureshi, PM | 1 |
| Geerlings, MI; Kloppenborg, RP; Nederkoorn, PJ; van der Graaf, Y | 1 |
| Agoşton-Coldea, L; Dobie, L; Lupu, S; Mărginean, A; Mocan, T | 1 |
| Bots, ML; Durga, J; Grobbee, DE; Kok, FJ; Schouten, EG; Verhoef, P | 1 |
| Liu, WH; Liu, WJ; Ma, LQ; Zhang, KQ; Zhou, W; Zou, CG | 1 |
| Chiarello, PG; Geleilete, TJ; Guerra, DC; Silva de Almeida, CC; Vannucchi, H; Vannucchi, MT | 1 |
| Kandel, M; Metreveli, N; Munjal, C; Pushpakumar, SB; Qipshidze, N; Tyagi, N; Tyagi, SC; Vacek, JC | 1 |
| Cuesta, J; Férnandez, C; García-Moll, X; Martí-Fabregas, J; Piñana, JL; Queraltó, JM; Remacha, AF; Rodriguez, A; Sardà, MP; Souto, JC | 1 |
| Antoniades, C; Bouras, G; Hatzis, G; Marinou, K; Miliou, A; Papageorgiou, N; Stefanadi, E; Stefanadis, C; Tousoulis, D; Tsioufis, C | 1 |
| Aspichueta, P; Botham, KM; Bravo, E; Buqué, X; Cano, A; Napolitano, M; Ochoa, B; Palleschi, S; Rossi, B | 1 |
| Du, XM; Feng, WY; Jia, G; Liu, LZ; Ma, YH; Song, YS; Wang, TC; Yan, L; Zhang, J; Zhang, N; Zhou, JW | 1 |
| Herrmann, M; Herrmann, W; Obeid, R; Schlundt, J; Umanskaya, N | 1 |
| Deng, Y; Duan, Y; Guo, J; Kuang, D; Wan, J; Wang, G; Xiao, G; Zhu, Y | 1 |
| Chrostek, L; Cylwik, B | 1 |
| Ahmadi, KR; Andrew, T; Clement, G; Cotlarciuc, I; Dew, T; Gill, R; Sherwood, R; Surdulescu, G | 1 |
| Bozard, BR; Ganapathy, PS; Ha, Y; Perry, E; Perry, RL; Roon, P; Smith, RM; Smith, SB; Tawfik, A | 1 |
| Chen, HJ; Di, RK; Gao, L; Guo, HM; Wu, XM; Wu, Y; Zeng, XN | 1 |
| Cheng, Z; Durante, W; Gupta, S; Jiang, X; Kruger, WD; Madesh, M; Mallilankaraman, K; Praticò, D; Schafer, AI; Wang, H; Yang, X | 1 |
| Clarke, R | 3 |
| Cavalca, V; Coppola, A; D'Angelo, A; Di Minno, G; Di Minno, MN; Palmieri, V; Pezzullo, S; Sampietro, F; Tremoli, E | 1 |
| Ali, JM; Mejia Mohamed, EH; Mohamed, Z; Tan, KS | 1 |
| Blood, J; Kharasch, ED; Nagele, P; Sharma, A; Tallchief, D | 1 |
| Praticò, D; Wang, H; Zhuo, JM | 1 |
| da Cunha, AA; da Cunha, MJ; Delwing, D; Kolling, J; Lima, DD; Scherer, EB; Schmitz, F; Sitta, A; Vargas, CR; Wyse, AT | 1 |
| Garlipp, CR; Gobbi, LT; Gobbi, S; Nascimento, CM; Santos, RF; Stella, F | 1 |
| Becker, DL; Coelho, JG; da Cunha, AA; da Cunha, MJ; Dutra-Filho, CS; Ferreira, AG; Pederzolli, CD; Wyse, AT | 1 |
| Giannoglou, GD; Tahiaos, P; Tsaousis, KT | 1 |
| Lau, YT; Ma, YH; Yen, CH; Yu, HP | 1 |
| Choi, D; Choi, KH; Han, SH; Hong, MK; Jang, Y; Kang, SW; Kim, BK; Kim, JS; Kim, SJ; Ko, YG; Yoo, TH | 1 |
| Grodnitskaya, EE; Kurtser, MA | 1 |
| Li, D; Ling, W; Lv, X; Ma, J; Qiu, J; Su, D; Xia, M; Xiao, Y; Zhang, Y | 1 |
| Dilger, RN; Garrow, TA; Gupta, S; Kruger, WD; Li, L; Strakova, J; Tryon, K | 1 |
| Hitri, K; Kondacs, A; Mandi, Y; Nedo, E; Somogyvari, F; Szaniszlo, I; Szekeres, M; Szolnoki, Z | 1 |
| Chang, HH; Chen, BY; Chen, YS; Lin, DP; Lin, W; Liu, HJ; Teng, MC; Tsao, ZJ | 1 |
| Carrilho, FJ; Muniz, MT; Oliveira, CP; Pereira, LM; Silva, F; Siqueira, ER | 1 |
| Atilla, P; Bitik, O; Çalş, M; Ersoy, US; Kamburoğlu, HO; Öcal, E; Pnar, A; Şafak, T; Sönmez, E; Uzun, H | 1 |
| Raman, R; Sukla, KK | 1 |
| Hur, M; Joo, SY; Kim, JQ; Ko, YJ; Moon, HW; Whang, DH; Yun, YM | 1 |
| Ahn, JK; Chang, S; Hong, IH; Park, SP | 1 |
| Brosnan, JT; Brosnan, ME; Lamarre, SG; Molloy, AM; Reinke, SN; Sykes, BD | 1 |
| Bochud, M; Marques-Vidal, PM; Marti, F; Mooser, V; Paccaud, F; Vollenweider, P; Waeber, G | 1 |
| Cai, Z; Jiang, Y; Lin, L; Pei, J; Shen, S; Wang, W; Xia, B; Xia, X; Xu, C; Zheng, B | 1 |
| Flood, VM; Gopinath, B; Mitchell, P; Rochtchina, E; Thiagalingam, A | 1 |
| Carmona Nava, LP; López Alarcón, M; López Domínguez, J; Montalvo Velarde, I; Vital Reyes, VS | 1 |
| Guéant, JL; Oussalah, A; Peyrin-Biroulet, L | 1 |
| Bouslama, A; Douki, W; Gaha, L; Mabrouk, H; Mechri, A; Najjar, MF; Omezzine, A; Younes, MK | 1 |
| Bocedi, A; Dawood, KF; Dessì, M; Fabrini, R; Federici, G; Fucci, G; Galli, F; Manca di Villahermosa, S; Massoud, R; Noce, A; Pastore, A; Ricci, G; Taccone-Gallucci, M; Zingaretti, V | 1 |
| Bogo, MR; Bonan, CD; Ferreira, AG; Savio, LE; Scherer, EB; Vuaden, FC; Wyse, AT | 1 |
| Feng, J; Li, J; Wang, X | 1 |
| Ayyagari, R; Balakrishna, N; Lopamudra, P; Mudili, S; Pitla, S; Reddy, GB; Reddy, PY; Satyanarayana, A; Suryanarayana, P; Viswanath, K | 1 |
| Badiou, S; Bargnoux, AS; Bosc, JY; Canaud, B; Chalabi, L; Cristol, JP; Jaussent, I; Leray-Moragues, H; Morena, M; Rodriguez, A | 1 |
| Stanger, O; Wonisch, W | 1 |
| D'Anci, KE; Dallal, GE; Dobson, B; Jacques, PF; Levey, AS; Moorthy, D; Rogers, G; Rosenberg, IH; Scott, TM; Selhub, J; Troen, AM; Weiner, DE | 1 |
| de Oliveira, GM; Luiz, RR; Rosa, G; Scorsatto, M; Uehara, SK | 1 |
| Blom, HJ; den Heijer, M; Hogeveen, M | 1 |
| Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M | 1 |
| Tyagi, SC; Vacek, JC; Vacek, TP | 1 |
| Akin, KO; Bilgili, SG; Ertugrul, DT; Karadag, AS; Tutal, E | 1 |
| Banks, WA; Beard, RS; Bearden, SE; Chen, CH; Ercal, N; Erickson, MA; Mayo, JN; Price, TO | 1 |
| Al-Farsi, YM; Al-Sharbati, MM; Ali, A; Deth, RC; Essa, MM; Waly, MI | 1 |
| Ganapathy, P; Peachey, NS; Smith, SB; Sturgill-Short, G; Tawfik, A; Yu, M | 1 |
| Ahmadian, S; Aryapour, H; Hoveizi, E; Karima, O; Khodadadi, S; Riazi, GH | 1 |
| Kang, RX; Zhang, JJ | 1 |
| Cho, CS; Kim, KJ; Kim, WU; Oh, IH; Park, SJ | 1 |
| Abaterusso, C; Bellinghieri, G; Cirillo, G; Cirillo, M; Coppola, S; De Santo, NG; Di Iorio, B; Ingrosso, D; Lanza, D; Lupo, A; Perna, AF; Raiola, I; Raiola, P; Santoro, D; Satta, E; Savica, V; Sepe, I; Tirino, G; Violetti, E | 1 |
| Cui, L; Handy, DE; Jiang, B; Joseph, J; Liao, R; Loscalzo, J; Pimental, D; Wang, X | 1 |
| Borowczyk, K; Jakubowski, H; Tisończyk, J | 1 |
| Cui, Y; Ge, J; Guan, D; Hu, J; Huo, Y; Li, J; Liu, Z; Qin, X; Wang, X; Wang, Y; Xu, X; Zhang, F; Zhao, Z | 1 |
| Cai, LL; Guo, LL; Jin, HM; Liu, XL; Pan, Y; Shu, JL; Zhu, XJ | 1 |
| Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
| Babicz, K; Malinowska, J; Olas, B; Oleszek, W; Stochmal, A | 1 |
| Brown, AT; Deng, H; Luo, S; Moursi, MM; Nyalala, JO | 1 |
| Champier, J; Claustrat, B; Claustrat, F; Fèvre Montange, M; Nazaret, N | 1 |
| Belcastro, V; Caccamo, D; Calabresi, P; Currò, M; Ferlazzo, N; Gorgone, G; Ientile, R; Parisi, G; Parnetti, L; Pisani, F; Rossi, A; Tambasco, N | 1 |
| Chen, Y; Hammock, BD; Kong, W; Xie, X; Zhang, D; Zhu, Y | 1 |
| Aouni, Z; El Oudi, M; Machghoul, S; Mazigh, C | 1 |
| Barkhordar, GS; Hellgren, M; Palmqvist, L; Parén, L; Zetterberg, H | 1 |
| Bochyńska, A; Graban, A; Gugała-Iwaniuk, M; Lechowicz, W; Lipczyńska-Łojkowska, W; Lipska, B; Restel, M; Ryglewicz, D | 1 |
| Ali, A; Bhargava, S; Parakh, R; Saxena, R; Srivastava, LM | 1 |
| B, BV; Dukat, A; Fodor, GJ; Lietava, J | 1 |
| Borowczyk, K; Jakubowski, H; Shih, DM | 1 |
| Agota, A; Joó, JG; Kriszbacher, I; Langmár, Z; Marosi, K; Nagy, ZB; Végh, V | 1 |
| Bhat, D; Joglekar, C; Katre, P; Lubree, H; Naik, S; Raut, K; Rege, S; Rush, E; Yajnik, C | 1 |
| Barone, E; Coppola, G; Ingrosso, D; Lattanzio, F; Matera, S; Operto, FF; Signoriello, G; Verrotti, A | 1 |
| Abchee, AB; Badro, DA; Cazier, JB; Chammas, E; Douaihy, B; el Bayeh, H; Gauguier, D; Ghassibe-Sabbagh, M; Haber, M; Hager, J; Kamatani, Y; Kibbani, S; Milane, A; Nemr, R; Othman, R; Platt, DE; Salloum, AK; Shasha, N; Stewart, K; Youhanna, S; Zalloua, PA | 1 |
| Durajski, L; Fijorek, K; Głowacki, R; Kozynacka, A; Mazur, P; Pfitzner, R; Sadowski, J; Undas, A | 1 |
| Alexandrova, LA; Blashko, EL; Chefu, SG; Cirlin, VA; Kuz'menko, NV; Zhloba, AA | 1 |
| Alexander, JS; Ganta, CV | 1 |
| Alis, R; de la Fuente, M; Hernández-Mijares, A; Laiz, B; Rivera, L; Romagnoli, M; Solá, E; Vayá, A | 1 |
| Azam, I; Chaudhry, B; Iqbal, MP; Moti, N; Parveen, S; Yakub, M | 1 |
| Devlin, AM; Singh, R; Sulistyoningrum, DC | 1 |
| Hamada, A; Mori, H; Mori, M; Taguchi, T; Yamori, Y | 1 |
| Bleich, S; Frieling, H; Haschemi-Nassab, M; Hillemacher, T; Kornhuber, J; Leitmeier, V; Rhein, M | 1 |
| Coley, DM; Givvimani, S; Kundu, S; Metreveli, N; Mishra, PK; Qipshidze, N; Sathnur, PB; Sen, U; Tyagi, N; Tyagi, SC | 1 |
| Assis, PA; Baggio, MS; Bassi, SC; Benício, MT; Falcão, RP; Figueiredo-Pontes, LL; Garcia, AB; Jácomo, RH; Lange, AP; Lima, AS; Oliveira, LO; Rego, EM; Santana-Lemos, BA | 1 |
| Alvarez, B; Fernández, E; Gené, A; Luccini, F; Matas, M; Yugueros, X | 1 |
| da Cunha, AA; da Cunha, MJ; Ferreira, AG; Grudzinski, PB; Hoppe, JB; Horn, AP; Loureiro, SO; Salbego, CG; Schmitz, F; Wyse, AT | 1 |
| Beck, B; Bossenmeyer-Pourié, C; Guéant, JL; Jeannesson, E; Richy, S | 1 |
| Antal, L; Bodog, A; Bodog, F; Micle, O; Muresan, M | 1 |
| Kolodziejczyk, J; Malinowska, J; Olas, B | 1 |
| Demidova, VS; Doguzhieva, RM; Lebedeva, AN; Pokrovskiĭ, AV | 1 |
| Loscalzo, J; Ueland, PM | 1 |
| Ben Abdallah, J; Charfeddine, B; Letaef, A; Limem, K; Naffeti, S; Othmen, LB; Smach, MA | 1 |
| Abais, JM; Boini, KM; Li, PL; Li, X; Liu, Q; Xia, M; Zhang, C | 1 |
| Lee, KJ; Min, JY; Min, KB; Park, JB | 1 |
| Abdessalem, S; Feki, M; Jemaa, R; Kaabachi, N; Kallel, A; Mechmeche, R; Mourali, MS; Sediri, Y | 1 |
| Liao, MT; Lin, YF; Lo, L; Lu, KC; Wu, CC; Zheng, CM | 1 |
| Asimi, S; Huang, T; Li, D; Lou, D | 1 |
| Bian, H; Chang, XX; Gao, X; Xia, MF; Xu, Q; Yan, HM; Zhu, TF | 1 |
| Almeida, OP; Flicker, L; Hankey, GJ; McCaul, KA; van Bockxmeer, FM; Wong, YY; Yeap, BB | 1 |
| Liu, Y; Liu, YQ; Morita, T; Sugiyama, K | 1 |
| Liu, Y; Liu, YQ; Mori, M; Morita, T; Sugiyama, K | 1 |
| Malinowska, J; Olas, B; Oleszek, W; Stochmal, A | 1 |
| Ehrlich, D; Humpel, C | 1 |
| Baer, DJ; Chen, K; Clifford, AJ; Fadel, JG; Holstege, DM; Kim, SH; Liu, B; McWade, L; Medrano, JF; Moshfegh, AJ; Müller, HG; Novotny, JA; Owens, JE; Rincon, G | 1 |
| Ankrah, A; Buscombe, J; Sathekge, MM | 1 |
| Chen, Y; Kong, W; Liu, J; Wang, Q; Xie, X; Zhang, D; Zhu, Y | 1 |
| Cheng, CH; Hou, CT; Huang, PN; Huang, YC; Wu, YH | 1 |
| Alfonso, H; Almeida, OP; Flicker, L; Hankey, GJ; McCaul, K; Yeap, BB | 1 |
| Gjessing, HK; Igland, J; Nygård, OK; Tell, GS; Ueland, PM; Vollset, SE | 1 |
| Lominadze, D; Ovechkin, A; Sen, U; Tyagi, N; Tyagi, SC | 1 |
| Slot, O | 1 |
| Kowalska, I; Kołodziejczyk-Czepas, J; Malinowska, J; Moniuszko-Szajwaj, B; Olas, B; Oleszek, W; Stochmal, A | 1 |
| Guarino, P; Joseph, J; Kaufman, J; Rafeq, Z; Roh, JD | 1 |
| Içağasioğlu, S; Kiliçli, F; Korkmaz, S; Yildiz, G; Yilmaz, A | 1 |
| Dąbrowski, W; Majdan, M; Nowicka-Stążka, P; Parada-Turska, J; Stążka, K; Turski, W | 1 |
| Abekhoukh, S; Delabar, JM; Janel, N; Paul, JL; Planque, C; Ripoll, C; Urbaniak, P | 1 |
| Hussain, S; Kazmi, AR; Malik, SA; Mustafa, M; Naeem, M; Qureshi, S | 1 |
| Ding, Y; Huang, Y; Li, XY; Liu, YP; Ma, YY; Song, JQ; Wang, Q; Wu, TF; Yang, YL | 1 |
| Fuster, V; Moreno, PR; Sanz, J | 1 |
| D'Almeida, V; Poloni, S; Schwartz, IV; Schweigert Perry, ID | 1 |
| Bartolomucci, F; Bonifazi, R; Brigiani, MS; Fattouch, K; Fiore, F; Gaudino, M; Gaudio, C; Lamarra, M; Nasso, G; Romano, V; Rosano, G; Speziale, G; Spirito, R | 1 |
| Bereczky, Z; Csiki, Z; Katona, É; Shemirani, AH; Zsóri, KS | 1 |
| Chen, K; Jin, X; Yan, L; Yin, G; Zhang, Z | 1 |
| Broda, G; Sygnowska, E; Waśkiewicz, A | 1 |
| Gustafson, L; Hultberg, B; Nilsson, K | 2 |
| Cerdena, I; Teng, YW; Zeisel, SH | 1 |
| Kurban, S; Mehmetoglu, I; Polat, H; Yerlikaya, FH | 1 |
| Gong, H; Jiang, Y; Shi, Y; Sun, T; Sun, W; Wang, J; Wei, J; Yang, B; Zhang, H | 1 |
| Kenet, G; Kuint, J; Kuperman, A; Lubetsky, A; Maayan-Metzger, A; Rosenberg, N; Sela, BA; Simchen, MJ; Strauss, T | 1 |
| Abais, JM; Boini, KM; Li, CX; Li, PL; Xia, M; Xu, M | 1 |
| Chang, N; Kim, G; Kim, H; Kim, KN; Kim, SY; Son, JI; Tamura, T | 1 |
| Babazadeh, H; Majidinia, M; Mehraban, K; Rasmi, Y; Sadreddini, M; Seyyed-Mohammadzad, M; Zeynalzadeh, J | 1 |
| Baudin, B; Chalghoum, A; Chkioua, L; Dandana, A; Ferchichi, S; Gammoudi, I; Jeridi, G; Khelil, S; Miled, A; Noichri, Y | 1 |
| Almeida, OP; Flicker, L; Hankey, GJ; McCaul, KA; Wong, YY; Yeap, BB | 1 |
| Cheng, X | 1 |
| Gamsjaeger, S; Klaushofer, K; Paschalis, EP; Rumpler, M; Spitzer, S; Thaler, R; Varga, F; Zwerina, J | 1 |
| Abais, JM; Boini, KM; Gehr, TW; Li, PL; Liu, Q; Xia, M; Zhang, C | 1 |
| Balasch, J; Carmona, F; Creus, M; Deulofeu, R; Peñarrubia, J | 1 |
| Trimmer, EE | 1 |
| Kim, H; Kim, JK; Kim, SK; Kwak, HC; Lee, MY; Lim, CH; Oh, SJ; Park, K; Yang, JS | 1 |
| Durmus, M; Kirbas, A; Oner, V; Sekeryapan, B; Turkyilmaz, K | 1 |
| Aung, KC; Feng, L; Ng, TP; Scherer, SC; Yap, KB | 1 |
| Abe, S; Aida, Y; Igarashi, A; Inoue, S; Kato, T; Kayama, T; Kishi, H; Konta, T; Kubota, I; Nunomiya, K; Sato, M; Shibata, Y; Ueno, Y; Watanabe, T; Yamashita, H; Yamauchi, K | 1 |
| Idris, S; McIlwee, A; Ukachukwu, V | 1 |
| Schalinske, KL; Smazal, AL | 1 |
| Babińska, A; Kaniuka-Jakubowska, S; Skibowska-Bielińska, A; Sowińska-Przepiera, E; Świątkowska-Stodulska, R; Sworczak, K; Wiśniewski, P | 1 |
| Chai, GS; Cheng, XS; Jiang, X; Liu, GP; Ma, ZW; Ni, ZF; Wang, JZ; Wang, Q; Xie, AJ | 1 |
| Feng, M; Guo, Z; He, ZM; Liu, LH; Wu, ZZ; Xiong, Y | 1 |
| Asmadi, AY; Azizi, A; Faizah, O; Kamisah, Y; Norsidah, KZ | 1 |
| Fennessey, PJ; Heneghan, HM; Hynes, N; Sultan, S; Tawfick, W; Waters, PS | 1 |
| An, SA; Kim, NK; Kim, OJ; Kim, SH; Kim, Y; Lee, HB; Oh, SH; Park, SY | 1 |
| Aleliunas, RE; Bottiglieri, T; Devlin, AM; Glier, MB; Ngai, YF; Sulistyoningrum, DC | 1 |
| de Andrade, RB; Ferreira, G; Gonçalves, CA; Hansen, F; Kolling, J; Scaini, G; Scherer, EB; Siebert, C; Streck, EL; Torres, FV; Wannmacher, CM; Wyse, AT | 1 |
| Duan, J; Hou, D; Jiang, D; Liu, T; Lu, L; Wang, W; Zhao, Q; Zhen, P | 1 |
| Deng, F; Guo, X; Hao, Y; Huang, J; Qin, Y; Shima, M; Wang, H; Wang, X; Wei, H; Wu, S; Zheng, C | 1 |
| Boldyrev, A; Bryushkova, E; Mashkina, A; Vladychenskaya, E | 1 |
| Chen, KJ; Chen, RC; Huang, YC; Lee, MS; Li, D; Wahlqvist, ML; Xiu, LL | 1 |
| Banecka-Majkutewicz, Z; Banecki, B; Kadziński, L; Sawuła, W; Węgrzyn, A | 1 |
| Kapoor, S | 1 |
| Ciment, S; Cueto, R; Jan, M; Meng, S; Pham, H; Tran, T; Wang, H; Yang, XF | 1 |
| Bopp, G; Hoefgen, B; Kallweit, U; Linnebank, M; Maier, W; Moskau, S; Schütz, CG; Semmler, A; Wüllner, U | 1 |
| Orlovsky, V; Zharkova, A | 1 |
| Chappell, DC; Dunnett, A; Obersby, D; Tsiami, AA | 1 |
| Mazur, P; Undas, A | 1 |
| Al-Shabrawey, M; Atherton, SS; Covar, JA; El-Remessy, A; Ganapathy, PS; Ganapathy, V; Matragoon, S; Roon, P; Smith, SB; Sonne, S; Tawfik, A | 1 |
| Liu, C; Wang, Q; Xu, H | 1 |
| Ascaso, JF; Chaves, FJ; Folgado, J; Gonzalez, R; Lorente, R; Martínez-Hervás, S; Molina, M; Priego, A; Real, JT | 1 |
| Ashraf, MZ; Behari, M; Chatterjee, T; Choudhry, VP; Gupta, N; Saxena, R | 1 |
| Ali, A; Bhargava, S; Das, S; Kankra, M; Manocha, A; Srivastava, LM | 1 |
| Bornstein, S; Julius, U; Müller, G; Rodionov, RN; Tselmin, S | 1 |
| Girard, CL; Guay, F; Matte, JJ | 1 |
| Elger, C; Linnebank, M; Moskau-Hartmann, S; Semmler, A; Stoffel-Wagner, B | 1 |
| Hayakawa, T; Isa, Y; Nakagawa, T; Yamamoto, K | 1 |
| Bo, S; Breda, S; Dall'Ara, P; Giordano, A; Paltrinieri, S; Pengo, G; Rossi, G | 1 |
| Brar, S; Carmel, R; Frouhar, Z; Mallidi, PV; Vinarskiy, S | 1 |
| Peters, WH; Raijmakers, MT; Roes, EM; Steegers, EA | 1 |
| Bostom, AG; Friedman, AN; Levey, AS; Rosenberg, IH; Selhub, J | 1 |
| Aitken, W; Chisholm, A; Harper, MJ; Mann, JI; Riddell, LJ; Rossaak, JI; Venn, BJ; Williams, SM | 1 |
| Guo, Q; Lu, J; Pan, C | 1 |
| Bacchi-Reggiani, L; Branzi, A; Carigi, S; Grigioni, F; Leone, O; Magelli, C; Magnai, G; Magnani, G; Poci, MG; Potena, L; Sassi, S; Sorbello, S | 1 |
| Adamek, L; Domagala, TB; Nizankowska, E; Sanak, M; Szczeklik, A | 1 |
| Carmel, R; James, SJ | 1 |
| Dán, A; Görögh, S; Locsey, L; Szegedi, J; Tóths, E | 1 |
| Hoffer, LJ | 2 |
| Cheong, HI; Choi, Y; Ha, IS; Hahn, H; Kang, HG; Lee, BS; Lee, JH | 1 |
| Delvin, EE; Genest, J; Lambert, M; Merouani, A; Rozen, R | 1 |
| Balla, J; Ben, T; Bereczky, Z; Kakuk, G; Kárpáti, I; Katona, E; Mohácsi, A; Muszbek, L; Páll, D; Paragh, G; Szóke, G; Toma, K; Varga, Z | 1 |
| Christensen, PB; Ekelund, S; Hansen, H; Jensen, OK; Mollerup, F; Rasmussen, C; Thulstrup, AM | 1 |
| Gala, JL; Hainaut, P; Heusterspreute, M; Jaumotte, C; Lavenne, E; Moriau, M; Verhelst, D; Wallemacq, P; Zech, F | 1 |
| Sainani, GS; Sainani, R | 1 |
| Karthikeyan, G; Prabhakaran, D; Reddy, KS | 1 |
| Shete, MM; Yeolekar, ME | 1 |
| Krishnaswamy, K; Lakshmi, AV | 1 |
| Ashavaid, TF; Dalal, JJ; Eghlim, FF; Nair, KG; Nair, SR | 1 |
| Carlsson, CM; Stein, JH | 1 |
| Atta, IA; Ben-Yehuda, A; Friedman, G; Goldschmidt, N; Haviv, YS; Shpichinetsky, V | 1 |
| Furie, KL; Kelly, PJ; Kistler, JP; Plomaritoglou, A; Rosand, J; Shih, VE; Silveira, S | 1 |
| Angelini, GD; Jeremy, JY; Shukla, N | 2 |
| Ghitescu, L; Gugliucci, A | 1 |
| Chen, YF; Li, PL; Zou, AP | 1 |
| Andersson, A; Hultberg, B; Jonasson, T; Lindgren, A; Ohlin, H | 1 |
| Lau, YT; Yen, CH | 1 |
| Aldámiz-Echevarría, L; Aquino, L; Gimeno, P; Pérez-Nanclares, G; Rodríguez-Soriano, J; Rueda, M; Ruiz, I; Sanjurjo, P; Urreizti, R; Vallo, A | 1 |
| Baydas, G; Canatan, H; Canpolat, S; Cikim, G; Gursu, MF; Kelestimur, H; Yasar, A | 1 |
| Deicher, R; Vierhapper, H | 1 |
| Doulgerakis, C; Karakasis, P; Kountouris, S; Kourvelou, C; Papagalanis, N; Rammos, G; Ziakka, S | 1 |
| Hirosawa, K; Hishida, A; Ikegaya, N; Katoh, S; Kimura, M; Kumagai, H | 1 |
| Blazícek, P; Krajcovicová-Kudlácková, M | 1 |
| Dear, AE; Grigg, MJ; Kuan, YM | 1 |
| Ghods, AJ; Porooshani, F; Rezakhani, S; Savaj, S | 1 |
| de Meer, K; Finglas, P; Smulders, Y; Stam, F; Stehouwer, CD; van den Akker, JT | 1 |
| Korczyn, AD | 1 |
| Dynan, KB; Lawson, JT; McIlroy, SP; Passmore, AP; Patterson, CC | 1 |
| Del Zotto, E; Padovani, A; Pezzini, A | 1 |
| Abrahamsson, L; Ahola, L; Møller, J | 1 |
| Chan, SP; Cheng, A; Ng, KC; Yong, QW | 1 |
| Apeland, T; Mansoor, MA; McNulty, H; Pentieva, K; Seljeflot, I; Strandjord, RE | 1 |
| Hasuike, Y; Itahana, R; Izumi, M; Miyagawa, K; Nakanishi, T; Nanami, M; Nishikage, H; Otaki, Y; Takamitsu, Y | 1 |
| Frick, B; Fuchs, D; Schröcksnadel, K | 1 |
| Agulló-Ortuño, MT; Albaladejo, MD; Fenollar, M; Martínez, P; Parra, S; Rodríguez-Manotas, M; Ruíz-Espejo, F; Tebar, J | 1 |
| Key, NS; McGlennen, RC | 1 |
| Hou, F; Hu, M; Yang, L; Yang, Y; Yu, Y; Zhang, X; Zhou, H | 1 |
| Adachi, K; Ishihara, S; Kinoshita, Y; Miyaoka, Y; Takashima, T; Yoshino, N; Yuki, T | 1 |
| O, K; Siow, YL; Sung, FL; Wang, G; Woo, CW | 1 |
| Barrera, G; Bunout, D; Escobar, E; Gattas, V; Glasinovic, A; Hirsch, S; Petermann, M; Pia De la Maza, M; Yañez, P | 1 |
| O'Donnell, J; Perry, DJ | 1 |
| Falk, E; Fuglsang, J; Møller, J; Ravn, HB; Stender, M; Zhou, J | 1 |
| Al-Salem, IH; Al-Salem, MH; Nkansa-Dwamena, D; Refai, TM | 1 |
| Caldera, A; Dec, GW | 1 |
| Bavbek, N; Gunduz, K; Kockar, MC; Korkar, MC; Okka, M; Oztürk, M; Rasier, Y | 1 |
| Isakov, I; Sharir, M | 1 |
| Hsieh, BS; Huang, JW; Pai, MF; Tsai, TJ; Wu, KD; Yen, CJ | 1 |
| Boiocchi, M; Corona, G; Innocenti, F; Mini, E; Russo, A; Sartor, F; Toffoli, G; Tumolo, S | 1 |
| Tonstad, S; Urdal, P | 1 |
| Bostom, AG; Eckfeldt, JH; Ellison, RC; Gravel, RA; Jacques, PF; Rich, S; Rozen, R; Selhub, J | 1 |
| Herrmann, W; Jouma, M; Obeid, R | 1 |
| Chasiotis, G; Elisaf, M; Miltiadous, G; Papakostas, J; Seferiadis, K | 1 |
| Arning, E; Bottiglieri, T; Brown, KL; Dayal, S; Faraci, FM; Lentz, SR; Oberley, LW; Weydert, CJ | 1 |
| Artner-Dworzak, E; Frick, B; Fuchs, D; Laich, A; Leblhuber, F; Widner, B | 1 |
| Abdella, NA; Akanji, AO; Mojiminiyi, OA; Moussa, MA | 1 |
| Heo, YR; Lim, HS | 1 |
| Blazícek, P; Krajcovicová-Kudlácková, M; Sebeková, K; Valachovicová, M | 1 |
| Akcakus, M; Halici, C; Karaküçük, I; Narin, F; Narin, N; Ustdal, M | 1 |
| Miller, JW | 2 |
| Abdelmouttaleb, I; Barbarino, P; Barbé, F; Boutroy, JL; Chéry, C; Gérard, P; Guéant, JL; Lequere, C | 1 |
| Benmerabet, S; Candito, M; Canivet, B; Fredenrich, A; Robillon, JF; Van Obberghen, E | 1 |
| Blom, HJ; Boers, GH; Den Heijer, M; Heil, SG; Kluijtmans, LA; Lievers, KJ; Trijbels, FJ; Verhoef, P | 1 |
| Nanayakkara, PW; Stehouwer, CD; van Guldener, C | 1 |
| Bandelow, B; Bleich, S; Degner, D; Havemann-Reinecke, U; Javaheripour, K; Kornhuber, J; Müller, A; Rüther, E; Sperling, W; Wilhelm, J | 1 |
| Diaz-Arrastia, R; Frol, AB; Rogers, JD; Sanchez-Saffon, A | 1 |
| Hunt, MJ; Sood, HS; Tyagi, SC | 1 |
| Barceló, M; Cadafalch, J; Fuster, M; Remacha, AF; Sardà, P | 1 |
| Blom, HJ; Kluijtmans, LA; Lievers, KJ | 1 |
| Castro, C; Chen, Z; Garrow, T; Genest, J; Laryea, MD; Lussier-Cacan, S; Mar, MH; Rozen, R; Schwahn, BC; Wendel, U; Zeisel, SH | 1 |
| Barron, M; Furie, KL; Kelly, PJ; Kistler, JP; Mandell, R; Picard, EH; Shih, VE | 1 |
| Green, T; Mann, J | 1 |
| Fuster, A; Garcia, A; Gibert, MJ; Hernanz, A; Martín, I; Obrador, A; Pintos, C; Tur, J | 1 |
| Chang, NS; Cho, CS; Chung, SY; Kang, MS; Kim, NK; Kim, SH; Na, BW; Oh, D; Park, S | 1 |
| Ambrosi, P; Artaud-Navarro, A; Barlatier, A; Boussuges, A; Bouvenot, G; Ferracci, A; Garçon, D; Habib, G; Luccioni, R | 1 |
| Alpérovitch, A; Ducros, V; Dufouil, C; Tzourio, C | 1 |
| Bambara, LM; Biasi, D; Caramaschi, P; Carletto, A; Faccini, G; Ferrari, M; Martinelli, N; Scambi, C; Volpe, A | 1 |
| Goldstein, M; Kurtz, S; Lazar, M; Leibovitch, I; Loewenstein, A; Sela, BA; Shemesh, G | 1 |
| Auch, D; Kaps, M; Osthaus, S; Rosengarten, B | 1 |
| Cuniberti, LA; Dominguez, GN; Fischer, PA; Martinez, V; Masnatta, LD; Ramirez, AJ; Werba, JP | 1 |
| Boskey, AL; Cole, DE; Donovan, SM; Hauschka, P; Howell, DS; Massé, PG; Ziv, I | 1 |
| Arnone, G; Forti, P; Maioli, F; Mariani, E; Muscari, A; Nativio, V; Ravaglia, G; Sacchetti, L; Talerico, T | 1 |
| Bridge, PJ; Fung, E; Hyndman, ME; Manns, BJ; Parsons, HG; Scott-Douglas, NW; Snyder, FF | 1 |
| Barcellona, D; Contu, P; Fenu, L; Marongiu, F; Pisu, G | 1 |
| Feroci, D; Ferri, S; Guerriero, G; Iachetta, RP; Scona, M; Stio, F; Stio, RE | 1 |
| Adam, B; Calikoğlu, E; Gürer, MA; Oztaş, M; Sengül, N | 1 |
| Miller, AL | 1 |
| Acantora, F; Cesare, CM; De Santo, NG; Ingrosso, D; Lombardi, C; Perna, AF; Satta, E | 1 |
| Devi, RR; Govindaiah, V; Jyothy, A; Kumar, KS; Naushad, SE | 1 |
| Arsava, EM; Ay, H; Ozer, N; Saribas, O; Tokgözoglu, SL | 1 |
| Frenkel, EP; Lee, R | 1 |
| Aukrust, P; Haugstad, TS; Holm, T; Holven, KB; Nenseter, MS; Ose, L | 1 |
| Abate, N; Cabo-Chan, AV; Chandalia, M; Devaraj, S; Grundy, SM; Jialal, I | 1 |
| Yang, ZZ; Zou, AP | 1 |
| Ahmed, R; Choudhry, VP; Gupta, M; Gupta, S; Saxena, R | 1 |
| Cheek, DJ; Coffey, M; Crowder, GK | 1 |
| Boreham, CA; Kluijtmans, LA; McMaster, D; McNulty, H; McPartlin, J; Murray, L; Scott, JM; Strain, JJ; Whitehead, AS; Young, IS | 1 |
| Calevo, MG; Canepa, A; Canini, S; Caridi, G; Carrea, A; Cerone, R; Dertenois, L; Minniti, G; Perfumo, F | 1 |
| Gao, L; Tang, CS | 1 |
| Haynes, WG | 1 |
| Arnadottir, M; Hultberg, B | 1 |
| Berthelot, A; Groubatch, F; Jacqueson, A; Laurant, P; Maupoil, V; Robin, S | 1 |
| Gustafson, L; Hultberg, B; Isaksson, A; Nilsson, K | 1 |
| Balas, D; Bouzigon, E; Emeriau, JP; Parrot, F; Rainfray, M; Salles-Montaudon, N | 1 |
| Dunbar, MS; Gallaher, MJ; Powers, RW; Roberts, JM | 1 |
| Feldman, RG; Miller, JW; Nadeau, MR; Selhub, J; Thomas, CA; Wolf, PA | 1 |
| Bleich, S; Kornhuber, J | 1 |
| Meissner, T | 1 |
| Boreham, CA; Brown, KS; Evans, AE; Kluijtmans, LA; McMaster, D; McNulty, H; Mitchell, LE; Murray, L; Strain, JJ; Whitehead, AS; Woodside, J; Yarnell, JW; Young, IS | 1 |
| Dijck-Brouwer, DA; Fokkema, MR; Muskiet, FA; Reijngoud, DJ; van Doormaal, JJ | 1 |
| Clarke, R; Landray, M; Lewington, S | 1 |
| Massy, ZA | 1 |
| Acanfora, F; Cesare, CM; De Santo, NG; Ingrosso, D; Lombardi, C; Perna, AF; Romano, MM; Satta, E; Violetti, E | 1 |
| Födinger, M; Sunder-Plassmann, G | 1 |
| Lailla, JM; López-Quesada, E; Vilaseca, MA | 1 |
| Calcagnotto, T; Matté, C; Streck, EL; Vieira, PS; Wajner, M; Wannmacher, CM; Wyse, AT | 1 |
| Cerula, SL; Huber, HA; Majors, AK; Powers, RW; Roberts, JM; Schmidt, BP | 1 |
| Boysen, G; Brander, T; Christensen, H; Gideon, R; Truelsen, T | 1 |
| Chang, JB; Chu, NF; Liang, YH; Shen, MH; Shieh, SM; Wu, DM | 1 |
| Fokkema, MR; Gilissen, MF; Kema, IP; Muskiet, FA; Van Doormaal, JJ; Volmer, M | 1 |
| Berner, YN; Doolman, R; Dror, Y; Gomori, JM; Isayev, M; Levy, S; Polyak, Z; Sela, BA; Stern, F | 1 |
| Bosy-Westphal, A; Czech, N; Fleig, W; Hinrichsen, H; Lotterer, E; Müller, MJ; Oehler, G; Plauth, M; Ruschmeyer, M | 1 |
| Ji, C; Kaplowitz, N | 2 |
| Chmiel, G; Czarnecka, D; Drozdz, M; Gozdecka, H; Kowalczyk-Michałek, M; Kraśniak, A; Małczak, J; Miłkowski, A; Moskal, K; Podwysocki, A; Sułowicz, W; Sydor, A; Szczeklik, A; Szmigielski, M; Wiecek, A; Zabawa-Hołyś, S | 1 |
| Echenne, B; Giraudier, S; Landrieu, P; Saudubray, JM; Tonetti, C; Zittoun, J | 1 |
| de Jong, N; Ferguson, EL; Gibson, RS; Green, TJ; Horwath, CC; McKenzie, JE; Skeaff, CM; Thomson, CD | 1 |
| Austin, RC; de Koning, AB; Dickhout, JG; Falk, E; Hossain, GS; Jacobsen, DW; Kaufman, RJ; Poddar, R; Sood, SK; Tang, D; van Thienen, JV; Werstuck, GH; Wu, D; Zhang, K; Zhou, J | 1 |
| Chiarello, PG; Vannucchi, H; Vannucchi, MT | 1 |
| Bayani, N; Blacher, J; Blondel, J; Coscas, G; Glacet-Bernard, A; Lelong, F; Nordmann, JP; Soubrane, G | 1 |
| Geisel, J; Herrmann, W; Obeid, R; Schorr, H; Zarzour, W | 1 |
| Mbewu, AD; Nogoduka, C; Taylor, B | 1 |
| Bernardino, L; Brito, AP; Fonseca, N; Inês, L; Santos, J; Silvestre, I; Vidal, N | 1 |
| Bazzano, LA; He, J; Muntner, P; Vupputuri, S; Whelton, PK | 1 |
| Hague, WM | 1 |
| Handy, DE; Loscalzo, J | 1 |
| Anábitarte, A; Díaz-Cremades, JM; Ferrario, CM; Fiuza, D; Hernández, E; Hernández-Perera, O; Losada, A; Rodríguez-Esparragón, F; Rodríguez-Pérez, JC; Yunis, C | 1 |
| Austin, RC; Falk, E; Larsen, ML; Møller, J; Ritskes-Hoitinga, M; Zhou, J | 1 |
| Favier, A; Galan, P; Guilland, JC; Hercberg, S; Potier de Courcy, G | 1 |
| Kowa, H; Nakashima, K; Nakaso, K; Takeshima, T; Yasui, K | 1 |
| Ben Abdallah, T; Ben Maiz, H; Feki, M; Fellah, H; Hsairi, M; Kaabachi, N; Lacour, B; Massy, ZA; Mebazaa, A; Sanhaji, H | 1 |
| Geisel, J; Herrmann, W; Obeid, R; Schorr, H | 1 |
| Farag, NH; Kennedy, BP; Mills, PJ; Ziegler, MG | 1 |
| Acartürk, E; Bozkurt, A; Cayli, M; Toyaksi, H; Tuli, A | 1 |
| Jofe, M; Liebmann, JM; Ritch, R; Vessani, RM | 1 |
| Hogan, K; Laxova, R; Rosenblatt, DS; Selzer, RR | 1 |
| Christiansen, K; Ebbesen, LS; Ingerslev, J | 1 |
| Deng, X; Huang, Q; Li, Y; Liu, H; Peng, H; Qiao, X; Sun, S | 1 |
| Battaglia Parodi, M; Di Crecchio, L | 1 |
| Badiwala, MV; Dhillon, B; Li, SH; Maitland, A; Rao, V; Verma, S | 1 |
| Holubec, L; Mayer, O; Pikner, R; Simon, J; Subrt, I | 1 |
| Benedetti, S; Buoncristiani, E; Buoncristiani, U; Canestrari, F; Conte, C; Floridi, A; Galli, F; Piroddi, M | 1 |
| de Gómez Dumm, NT; Giammona, AM; Touceda, LA | 1 |
| Morris, MS | 1 |
| Blann, A; Lip, GY; Nadar, S | 1 |
| Ceska, R; Grauova, B; Haas, T; Hradec, J; Kozich, V; Krijt, J; Malik, J; Melenovsky, V; Stulc, T; Wichterle, D | 1 |
| Gilfix, BM | 1 |
| Buysschaert, M; Hermans, MP | 1 |
| Aro, A | 1 |
| Contino, L; Demicheli, M; Fiorini, T; Levis, A; Santi, R | 1 |
| Hoffman, M; Sauls, DL; Wolberg, AS | 1 |
| Catena, G; Colistro, F; Danesi, H; Di Ciommo, V; Di Donato, RM; Fina, F; Giannone, G; Parisi, F | 1 |
| Bohle, B; Födinger, M; Hörl, WH; Kletzmayr, J; Papagiannopoulos, M; Sengoelge, G; Sunder-Plassmann, G | 1 |
| Minagawa, T; Oda, H; Ohashi, H; Ohkuma, T; Ohno, M; Takada, N | 1 |
| Bleich, S; Kornhuber, J; Wiltfang, J | 1 |
| Deussen, A | 1 |
| Blom, HJ; Boers, GH; Riksen, NP; Rongen, GA; Russel, FG; Smits, P | 1 |
| Cooke, JP; Graf, EE; Kapoor, O; Malinow, MR; Oka, RK; Pachinger, O; Schmölzer, I; Stühlinger, MC; Szuba, A; Upson, BM; Wascher, TC | 1 |
| Cheng, C; Cook, EH; Das, S; Griener, J; Hudson, M; Kishi, S; Pei, D; Pui, CH; Relling, MV; Rubnitz, J; Sandlund, JT | 1 |
| Anello, G; Barone, C; Bosco, P; Caraci, F; Guéant, JL; Guéant-Rodriguez, RM; Namour, F; Romano, A; Romano, C | 1 |
| Lip, GY; Nadar, S | 1 |
| Stabler, SP | 1 |
| Allen, LH; Green, R; Haan, MN; Jagust, WJ; Miller, JW; Mungas, DM; Ramos, MI | 1 |
| D'Almeida, V; Martins, PJ; Perez, AB; Tufik, S; Vergani, N | 1 |
| Aso, Y; Inukai, T; Okumura, K; Takebayashi, K; Wakabayashi, S | 1 |
| Costa, T; Faria, MS; Fonseca, I; Henriques, AC; Mota, C; Pereira, E; Pereira, M; Santos, MJ; Sarmento, AM | 1 |
| Austin, RC; Lawrence de Koning, AB; Werstuck, GH; Zhou, J | 1 |
| Algra, A; Banga, JD; de Valk, HW; Grobbee, DE; van de Laak, MF; van der Graaf, Y; van der Griend, R | 1 |
| Errasti, P; Garcia-Fernández, N; Hernandez, A; Lavilla, J; Manrique, J; Pujante, D; Purroy, A; Rossich, E | 1 |
| BRENTON, DP; CUSWORTH, DC; GAULL, GE | 1 |
| Also-Rayo, E; López-Quesada, E; Vilaseca, MA | 1 |
| Holmes, VA | 1 |
| Araya, J; Orellana, M; Passalacqua, W; Rivera, G; Rodrigo, R | 2 |
| Nakanishi, T; Sass, JO; Sato, T; Shimizu, A; Sperl, W | 1 |
| Bocchini, JA; Kooragayala, LM; Thurmon, TF; Yanamandra, K | 1 |
| Aranda, JM; Cleeton, TS; Hill, JA; Schofield, RS; Walker, TC; Wessel, TR | 1 |
| Cole, DE; Delgado, DH; Miriuka, SG; Rao, V; Ross, HJ | 1 |
| Chotkowska, E; Dzielińska, Z; Gaździk, D; Janas, J; Kadziela, J; Piotrowski, W; Ruzyłło, W; Szperl, M | 1 |
| Caso, V; Gallai, V | 1 |
| Duraisamy, G; Ling, KH; Nasir, MT; Rosli, R | 1 |
| Chada, L; McGaw, J; Nakano, E; Powers, HJ; Taylor, CJ | 1 |
| Ateş, A; Aydintuğ, O; Duman, M; Düzgün, N; Olmez, U | 1 |
| Cucinotta, D; Russo, GT | 1 |
| Albertini, F; Archetti, S; Assanelli, D; Bonanome, A; Grassi, M; Maccalli, P; Negrini, R; Pezzini, A; Visioli, F | 1 |
| D'Agostino, RB; Jacques, PF; Levy, D; Rosenberg, IH; Selhub, J; Sullivan, L; Sundström, J; Vasan, RS; Wilson, PW | 1 |
| Bamford, JM; Bell, R; D'Souza, R; Hassan, A; Hunt, BJ; Jeffery, S; Markus, HS; O'Sullivan, M | 1 |
| Gao, X; Li, Y; Ma, G; McCrory, MA; Roberts, SB; Tucker, KL; Yao, M | 1 |
| Abbate, R; Brunelli, T; Evangelisti, L; Fedi, S; Gensini, GF; Giusti, B; Pepe, G; Porciani, MC; Sani, G; Yacoub, M | 1 |
| Derbeneva, SA; Pogozheva, AV | 1 |
| Schulz-Hanke, I | 1 |
| Oron-Herman, M; Rosenthal, T; Sela, BA | 1 |
| Czeizel, E; Kalina, A | 1 |
| Alonso, B; Benetucci, J; de Larrañaga, G; Puga, L | 1 |
| Au-Yeung, KK; O, K; Siow, YL; Sung, FL; Woo, CW; Yip, JC | 1 |
| Carmel, R; Green, R; Rosenblatt, DS; Watkins, D | 1 |
| Sela, BA; Tanne, D | 1 |
| Borzone, L; Cancino, M; Casanueva, V; Cid, L; Cid, X | 1 |
| Tsikas, D | 1 |
| Frick, B; Fuchs, D; Herold, M; Kaser, S; Ledochowski, M; Mur, E; Schroecksnadel, K; Wirleitner, B | 1 |
| Liu, H; Peng, YM; Wang, HT | 1 |
| Herrmann, W | 2 |
| Dierkes, J; Fowler, B; Geisel, J; Herrmann, W; Pietrzik, K; Stanger, O; Weger, M | 2 |
| Stehouwer, CD; van Guldener, C | 2 |
| Monsen, AL; Ueland, PM | 1 |
| Bodis, M; Geisel, J; Herrmann, W; Hübner, U; Knapp, JP; Obeid, R; Schorr, H | 1 |
| Frick, B; Fuchs, D; Leblhuber, F; Schroecksnadel, K; Winkler, C; Wirleitner, B | 1 |
| Stanger, O; Weger, M | 1 |
| Heydrick, SJ; Keaney, JF; Keller, C; Loscalzo, J; Postea, O; Weiss, N | 1 |
| Harrington, DJ; Kovacs, JA; Rangarajan, S; Savidge, GF; Shearer, MJ; Sobczyńska-Malefora, A | 1 |
| Geisel, J; Hennen, B; Herrmann, W; Hübner, U; Knapp, JP | 1 |
| Atkins, RC; Branley, P; Kerr, PG; McGrath, BP; McNeil, JJ; Polkinghorne, KR; Villanueva, E; Zoungas, S | 1 |
| Lutgens, E; Rosenberg, IH; Selhub, J; Smith, DE; Troen, AM | 1 |
| Aharonian, VJ; Burchette, RJ; Jorgensen, MB; Kojoglanian, SA; Wolde-Tsadik, G | 1 |
| De Santo, NG; Ingrosso, D; Perna, AF | 1 |
| Gauthier, GM; Keevil, JG; McBride, PE | 1 |
| Clement, L | 1 |
| Harrington, DJ; Kapustin, SI; Papayan, LP; Savidge, GF; Shmeleva, VM; Sobczyńska-Malefora, A | 1 |
| Axer-Siegel, R; Benjamini, Y; Bourla, D; Dotan, G; Ehrlich, R; Gavendo, S; Sela, BA; Weinberger, D | 1 |
| Cobelli, M; Marietta, M; Panini, R; Rosa, MC; Salvioli, G; Ventura, P | 1 |
| Qiu, L; Song, YH; Yan, SK | 1 |
| Atabek, ME; Erkul, I; Pirgon, O | 1 |
| Algra, A; Bloemenkamp, DG; Blom, HJ; Rosendaal, FR; Tanis, BC; van den Bosch, MA; van der Graaf, Y | 1 |
| Gurwitz, D; Habano, W; Itoh, C; Nakai, K | 1 |
| Chiarello, PG; Moysés Neto, M; Vannucchi, H; Vannucchi, MT | 1 |
| Baviera, G; Corrado, F; D'Anna, R; Granese, D; Ientile, R; Stella, NC | 1 |
| Faraci, FM; Lentz, SR | 1 |
| Emiliani, S; Panini, R; Salvioli, G; Ventura, P | 1 |
| Fleischer, W; Görtz, P; Hoinkes, A; Otto, F; Schwahn, B; Siebler, M; Wendel, U | 1 |
| Berthelot, A; Courderot-Masuyer, C; Jacqueson, A; Nicod, L; Richert, L; Robin, S | 1 |
| Clarke, ZL; Goodfellow, J; Lang, D; Lewis, MJ; Madhavan, AK; McDowell, IF; Moat, SJ | 1 |
| Rauwerda, JA; Stehouwer, CD; Twisk, JW; van Campen, CM; van Engeland, MI; Vermeulen, EG; Visser, FC | 1 |
| Agelink, MW; Andrich, J; Arz, A; Kraus, PH; Kuhn, W; Müller, T; Saft, C; Schneider, B | 1 |
| Ambrosi, P | 1 |
| Cap, AP; Heydrick, SJ; Keaney, JF; Loscalzo, J; Pimentel, DR; Thomas, SR; Weiss, N | 1 |
| Di Rocco, A; Werner, P | 1 |
| Fuchs, D; Leblhuber, F; Schroecksnadel, K | 1 |
| Cheng, J; Guo, H; Lee, JD; Shan, J; Ueda, T; Wang, J | 1 |
| Andriolo, A; Franco, LJ; Gimeno, SG; Perez, AB; Sañudo, A; Tavares, EF; Vergani, N; Vieira-Filho, JP | 2 |
| Huffman, FG; Koutoubi, S | 2 |
| Dierkes, J; Luley, C; Westphal, S | 2 |
| Austen, SK; Coombes, JS; Fassett, RG | 1 |
| Kalra, DK | 1 |
| Chang, SJ; Chang, TW; Lee, YC; Liu, SY | 1 |
| Aupetit, J; Chassé, JF; Janel, N; Kamoun, P; London, J; Paly, E; Robert, K; Santiard-Baron, D | 1 |
| Benjamin, EJ; D'Agostino, RB; Jacques, PF; Levy, D; Rosenberg, IH; Selhub, J; Sullivan, L; Sundström, J; Vasan, RS; Wilson, PW | 1 |
| Agarwal, N; Ganapathy, V; Martin, PM; Ola, MS; Smith, SB | 1 |
| Alexander, SR; Belson, A; Dar, MH; Reif, S; Salvatierra, O; Sanchez, J; Yorgin, PD | 1 |
| Choy, PC; Mymin, D; O, K; Siow, YL | 1 |
| Dagalp, K; Erbil, MK; Kocar, IH; Musabak, U; Oktenli, C; Pay, S; Saglam, K; Sanisoglu, SY; Yesilova, Z | 1 |
| Sachdev, P | 1 |
| Edirisinghe, SP | 1 |
| Bottiglieri, T; Caso, V; Conte, C; Corea, F; Floridi, A; Lanari, A; Parnetti, L; Santucci, A | 1 |
| Cole, DE; Delgado, DH; Evrovski, J; Keren, ES; Langman, LJ; Mamer, OA; Miner, SE; Miriuka, SG; Ross, HJ | 1 |
| Arnesen, H; Bates, CJ; Knudsen, A; Larsen, TW; Mansoor, MA; Mishra, G; Seljeflot, I | 1 |
| Acanfora, F; De Santo, NG; Ingrosso, D; Lombardi, C; Perna, AF; Satta, E | 2 |
| Bleich, S; Bönsch, D; Degner, D; Kornhuber, J; Sperling, W; Thürauf, N | 1 |
| Daftary, AR; Ness, RB; Patrick, TE; Powers, RW; Roberts, JM | 1 |
| Amiri, F; Endemann, D; Neves, MF; Pu, Q; Rozen, R; Schiffrin, EL; Virdis, A | 1 |
| Blom, HJ; Den Heijer, M; Heil, SG; Kluijtmans, LA; Van Der Rijt-Pisa, BJ | 1 |
| Abassi, Z; Brenner, B; Green, J; Khankin, E; Lanir, N; Nakhoul, F; Plawner, M; Ramadan, R | 1 |
| Barron, JL; Saldana Chaparro, R | 1 |
| Di Crecchio, L; Iacono, P; Parodi, MB; Ravalico, G; Sanguinetti, G | 1 |
| Arcaro, G; Dagradi, R; Degan, M; Faccini, G; Fava, C; Gaino, S; Lechi, A; Lechi, C; Minuz, P | 1 |
| Qi, JS; Qiao, JT; Qin, Y | 1 |
| Hou, FF; Liu, ZQ; Yu, YM; Zhang, X; Zhou, H | 1 |
| Gavendo, S; Goldstein, M; Leibovitch, I; Loewenstein, A; Sela, BA; Yeffimov, I | 1 |
| Castro, C; Garrow, TA; Leclerc, D; Lussier-Cacan, S; Mar, MH; Rozen, R; Schwahn, BC; Wendel, U; Zeisel, SH | 1 |
| Bisschops, RH; Mali, WP; van der Graaf, Y; van der Grond, J | 1 |
| Breteler, MM; de Groot, LC; de Jonge, R; Dhonukshe-Rutten, RA; Hofman, A; Lindemans, J; Lips, P; Pluijm, SM; Pols, HA; Uitterlinden, AG; van der Klift, M; van Leeuwen, JP; van Meurs, JB; Witteman, JC | 1 |
| Broe, KE; Cupples, LA; Hannan, MT; Jacques, PF; Kiel, DP; McLean, RR; Samelson, EJ; Selhub, J; Tucker, KL | 1 |
| Raisz, LG | 1 |
| Bovenzi, F | 1 |
| Di Sabato, F | 1 |
| Casciani, S; Cortese, C; De Angelis, S; Dessì, MR; Federici, G; Ferranini, M; Liberatoscioli, L; Pastore, A; Splendiani, G; Tullio, T | 1 |
| Behrmann, C; Heins, S; Podhaisky, H; Taute, BM; Taute, R | 1 |
| Holubec, L; Mayer, O; Pikner, R; Simon, J; Trefil, L; Vobrubová, I | 1 |
| Sztenc, S | 1 |
| Green, R; Luchsinger, JA; Mayeux, R; Miller, J; Shea, S; Tang, MX | 1 |
| De Caterina, R; Fioretti, P; Madonna, R; Vanuzzo, D; Zampolli, A | 1 |
| Aras, O; Arends, VL; Hanson, NQ; Hunninghake, DB; Matas, AJ; Sozen, H; Tsai, MY; Woll, PS | 1 |
| Malinow, MR; Muy-Rivera, M; Qiu, C; Sanchez, SE; Vadachkoria, S; Williams, MA | 1 |
| Hartnett, ME; Laposata, M; Van Cott, EM | 1 |
| Börner, C; Dambrink, JH; De Luca, G; Dille, J; Kallmayer, K; Lange, H; Pasalary, MN; Scherer, E; Suryapranata, H | 1 |
| Hennekens, CH; Lamas, GA; Splaver, A | 1 |
| Aléssio, AC; Annichino-Bizzacchi, JM; Bydlowski, SP; Eberlin, MN; Höehr, NF; Vellasco, AP | 1 |
| Black, J; Bryda, EC; Cansino, S; Chappell, J; Hunt, L; Parris, C; Studeny, M; Walker, E; Wehner, P; Wright, GL | 1 |
| Vasa-Nicotera, M | 1 |
| Austin, RC; Lentz, SR; Werstuck, GH | 1 |
| Bavaresco, CS; Netto, CA; Streck, EL; Wyse, AT | 1 |
| Eren, M; Koçak, N; Nur Saltik-Temizel, I | 1 |
| Frick, B; Fuchs, D; Schroecksnadel, K | 1 |
| Nishio, I; Tsuda, K | 1 |
| Allen, RH; Lee, HS; Paik, MC; Sacco, RL; Stabler, SP; Wright, CB | 1 |
| Allasino, B; Angeli, A; Aroasio, E; Bosio, S; Brusa, E; Camaschella, C; Daffara, F; Reimondo, G; Sacchetto, G; Terzolo, M; Ventura, M | 1 |
| Bots, ML; Durga, J; Schouten, E; Verhoef, P | 1 |
| Black, MJ; Buxton, BF; Hare, DL; Zulli, A | 1 |
| Zák, A; Zeman, M | 1 |
| Bleie, Ø; Guttormsen, AB; Nexo, E; Nordrehaug, JE; Nygård, O; Refsum, H; Schneede, J; Ueland, PM; Vollset, SE | 1 |
| Qian, LJ; Wu, SQ | 1 |
| Adachi, T; Morishita, T; Nakashima, Y; Nihei, S; Okazaki, M; Ozumi, K; Tasaki, H; Tsutsui, M; Yamashita, K | 1 |
| Hata, J; Hirakata, H; Iida, M; Kato, I; Kiyohara, Y; Kubo, M; Nakamura, H; Ninomiya, T; Oishi, Y; Okubo, K; Tanaka, K; Tanizaki, Y | 1 |
| Alvestrand, A; Anderstam, B; Bárány, P; Heimburger, O; Lindholm, B; Qureshi, AR; Stenvinkel, P; Suliman, ME | 1 |
| Auer, J; Eber, B; Lamm, G | 1 |
| Bursztyn, M | 1 |
| Arranz-Peña, ML; Luis, DD; Pérez-Castrillón, JL | 1 |
| Ellenberg, SS; Orloff, DG; Temple, RJ | 1 |
| Al Khader, A; Al Mofawaz, TA; Al Suliman, M; Khan, SA; Saadeddin, SM; Sobki, SH | 1 |
| Lang, AE; Postuma, RB | 1 |
| Deng, Q; Ji, C; Kaplowitz, N | 1 |
| Fernández, S; González, S; Huerta, JM; Lasheras, C; Patterson, AM; Prada, M; San Martín, J; Vigil, E | 1 |
| Chillemi, R; Musumeci, M; Musumeci, S; Persichilli, S; Simporè, J; Zappacosta, B | 1 |
| Aso, Y; Inukai, T; Matsutomo, R; Okumura, K; Takebayashi, K; Wakabayashi, S; Yoshida, N | 1 |
| Fowler, B; Herrmann, W; Stanger, O | 1 |
| Chang, HW; Cheng, TT; Lai, HM; Luo, SF | 1 |
| Asmis, R; Haefeli, WE; Linder, L; Litynsky, P; Nyfeler, J; Romerio, SC; Wenk, M | 1 |
| Eliasziw, M; Freeman, DJ; House, AA; Spence, JD; Urquhart, BL | 1 |
| Delabar, J; Janel, N; Ledru, A; Maurin, N; Robert, K | 1 |
| Gürdöl, F; Isbilen, E; Isbir, T; Unlüçerçi, Y; Yilmaz, H | 1 |
| Aeschlimann, SE; Carlsson, CM; Mitchell, C; Pharo, LM; Stein, JH; Underbakke, G | 1 |
| Fowler, B; Heun, R; Jeub, M; Klockgether, T; Koch, HG; Kölsch, H; Linnebank, A; Linnebank, M; Suormala, T; Wüllner, U | 1 |
| Bhat, G; Costea, A | 1 |
| Carson, RJ | 1 |
| Enokido, Y; Harada, T; Ishii, I; Kimura, H; Nagai, Y; Namekata, K | 1 |
| Roth, E; Szabo, T; Szamosi, T; Tomsits, E; Tordai, A | 1 |
| Kotel'nikov, MV | 1 |
| Haynes, WG; Lentz, SR | 1 |
| Bárány, P; Kalantar-Zadeh, K; Lindholm, B; Stenvinkel, P; Suliman, ME | 1 |
| Caram, SG; Dominguez, GN; Fischer, PA; Masnatta, LD; Monserrat, AJ; Ossani, GP | 1 |
| Brouns, RM; de Jonge, R; Griffioen, PH; Lindemans, J; van Zelst, B; Visser, W | 1 |
| Guldiken, S; Kilic-Okman, T; Kucuk, M | 1 |
| Jołda-Mydłowska, B | 1 |
| Arakawa, N; Bode-Böger, SM; Böger, RH; Hornig, B; Münzel, T; Sydow, K; Tsikas, D | 1 |
| Bessomo, A; Buysschaert, M; Gala, JL; Hermans, MP | 1 |
| Cheng, J; Geshi, T; Guo, H; Lee, JD; Toyoda, K; Ueda, T; Xing, Y | 1 |
| Amato, NA; Celeste, T; Del Bianco, A; Fulgieri, AM; Lombardi, L; Maruotti, G; Pietropaolo, F | 1 |
| Bednarek-Tupikowska, G; Tupikowski, K | 1 |
| Blom, HJ; Boers, GH; Riksen, NP; Rongen, GA; Smits, P; van den Broek, PH | 1 |
| Geisel, J; Herrmann, W; Hübner, U; Koch, I; Obeid, R; Retzke, U | 1 |
| Accadia, M; Alberta Ortali, V; Ascione, L; De Michele, M; Inserviente, L; Petti, M; Rumolo, S; Russo, G; Sacra, C; Tuccillo, B | 1 |
| Chandraker, A; Curhan, GC; Endler, G; Födinger, M; Hörl, WH; Kramar, R; Sunder-Plassmann, G; Winkelmayer, WC | 1 |
| De Bacquer, D; De Vriese, AS; Delanghe, JR; Geerolf, I; Lameire, NH; Langlois, M; Stevens, L; Taes, YE | 1 |
| Chu, PL; Chu, TS; Hsu, SP; Huang, JW; Shih, KY; Wu, KD; Yang, SY | 1 |
| El Matri, L; Feki, M; Ghannouchi, M; Hamzaoui, K; Houman, H; Kaabachi, N; Mebazaa, A; Smiti-Khanfir, M | 1 |
| Chang, N; Ha, EH; Kim, KN; Kim, YJ; Park, H | 1 |
| Nakata, R; Okawa, N; Shigematsu, N; Yagisawa, M | 1 |
| Devi, S; Hauer-Jensen, M; Joseph, J; Joseph, L; Kennedy, RH; Wang, J | 1 |
| de Meer, K; Jakobs, C; Stam, F; Stehouwer, CD; Ter Wee, PM; van Guldener, C | 1 |
| Ikegaya, N; Kumagai, H; Yanagisawa, C | 1 |
| Cole, DE; D'Mello, N; Delgado, DH; Evrovski, J; Langman, LJ; Miner, SE; Miriuka, SG; Ross, HJ; Wong, BY | 1 |
| Helkamaa, T; Larjonmaa, H; Nissinen, E; Nissinen, H; Rauhala, P; Reenilä, I; Väänänen, A | 1 |
| Fernández, S; González, S; Huerta, JM; Lasheras, C; Patterson, AM | 1 |
| Janel, N; Maurin, N; Robert, K; Siauve, N; Vayssettes, C | 1 |
| Ahmadi, M; Biniszkiewicz, D; Endres, M; Gertz, K; Kruman, I; Meisel, A | 1 |
| Chassé, JF | 1 |
| Crone, J; Falger, J; Födinger, M; Huemer, C; Huemer, M; Sailer-Höck, M; Ulmer, H | 1 |
| Choy, PC; Minuk, GY; Mymin, D; O, K; Pierce, GN; Siow, YL; Woo, CW | 1 |
| Barut, Y; Direskeneli, H; Inanc, N; Ozdemir, A; Sahinoglu, S; Tarcin, O; Tiftikci, A; Uras, F; Yavuz, S | 1 |
| Niwa, T; Takayama, F; Taki, K | 1 |
| Chua, B; Kifley, A; Mitchell, P; Wong, TY | 2 |
| Blazícek, P; Ginter, E; Krajcovicová-Kudlácková, M; Valachicová, M | 1 |
| Araújo, F; Bates, CJ; Blom, HJ; Bouter, LM; Cunha-Ribeiro, LM; de Bree, A; Dekker, JM; Dierkes, J; Galan, P; Heine, RJ; Herrmann, W; Mennen, LI; Nijpels, GN; Nygard, O; Refsum, H; Stehouwer, CD; Ueland, PM; Ullrich, M; van der Put, NM; Verschuren, WM; Vollset, S; Westphal, S | 1 |
| Fathi, Z; Golbahar, J; Tamadon, M | 1 |
| Carroli, G; Khan, KS; Kilby, MD; Latthe, PM; Mignini, LE; Villar, J | 1 |
| Abbud-Filho, M; Baptista, MA; Eberlin, MN; Goloni-Bertollo, EM; Haddad, R; Hoerh, NF; Pavarino-Bertelli, EC; Sanches de Alvarenga, MP | 1 |
| Almarza, C; Carvajal, C; Foncea, R; Leighton, F | 1 |
| Guilhem, S; Igor, S; Isabelle, RV | 1 |
| Alam, MK; Arslan, MI; Banu, S; Hamid, MA; Mollah, FH; Rahman, MA; Wahab, MA | 1 |
| Kameda, G; Mayatepek, E; Schwahn, B; Wessalowski, R | 1 |
| Ebbesen, LS | 1 |
| Giusti, B; Lapini, I; Lenti, M; Marcucci, R; Pepe, G; Sestini, I; Yacoub, M | 1 |
| Stanger, O | 1 |
| Alpers, DH | 1 |
| Cetinkaya, A; Guven, MA | 1 |
| Racek, J; Rusnáková, H; Siala, KK; Trefil, L | 1 |
| Stanger, O; Stühlinger, MC | 1 |
| van Guldener, C | 2 |
| Weiss, N | 1 |
| Meloni, GF; Musumeci, S; Tonolo, GC; Zappacosta, B; Zuppi, C | 1 |
| Antònia Vilaseca, M; Gómez, E; Lailla, JM; López-Quesada, E | 1 |
| Chang, N; Kim, HJ; Kim, JM; Lee, H; Lee, I | 1 |
| Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S | 1 |
| Andersen, ML; Benedito-Silva, AA; D'Almeida, V; Galdieri, LC; Martins, PJ; Souza, FG; Tufik, S | 1 |
| Li, W; Li, WP; Yang, T | 1 |
| Beck, GJ; Greene, T; Kusek, JW; Levey, AS; Menon, V; Sarnak, MJ; Selhub, J; Wang, X | 1 |
| Hase, K; Sakuta, H; Suzuki, T; Wakiyama, H; Yasuda, H | 1 |
| Aguilar, B; Collados, MT; Rojas, JC | 1 |
| Abbate, R; Gori, AM; Marcucci, R | 1 |
| Kozlova, TV | 1 |
| Armenise, E; de Mari, M; Fraddosio, A; Iliceto, G; Lamberti, P; Lamberti, SV; Livrea, P; Zoccolella, S | 1 |
| Blom, HJ; Den Heijer, M; Hoogendoorn, ML; Kahn, RS; Kluijtmans, LA; Muntjewerff, JW; Sinke, RJ | 1 |
| Bokhari, SW; Bokhari, ZW; Faxon, DP; Lee, DW; Zell, JA | 1 |
| D'Almeida, V; Dabela, ML; Fonseca, FA; Helfenstein, T; Izar, MC; Matheus, SC; Relvas, WG; Rodrigues, PR; Santos, AO; Sousa, EF; Souza, FG; Taglieri, R; Tufik, S | 1 |
| Tan, HM; Wang, H; Yang, F | 1 |
| Dowey, L; McNulty, H; Pentieva, K; Strain, JJ; Ward, M | 1 |
| Fu, JF; He, J; Huang, XM; Jiang, GP; Yu, ZS; Zhang, YY; Zhu, WH | 1 |
| Li, XF; Wang, LY; Xiao, CS; Xu, XY; Zhou, WH | 1 |
| Lu, SC; Mato, JM | 1 |
| de la Peña, P; Fernández-Miranda, C; Gómez de la Cámara, A; Gómez, P; Penas, M; Saiz, R | 1 |
| Coto, A; Fernández-Miranda, C; Gómez de la Cámara, A; Gómez, P; Martínez, J | 1 |
| González Ordóñez, AJ | 1 |
| Blanco Vaca, F; González Sastre, F; Llevadot, J | 1 |
| Boxer, AL; Finley, R; Goldman, J; Johnston, K; Kramer, JH; Miller, BL | 1 |
| Bronstein, J; Guarnieri, M; Hubble, J; Kang, GA; Ostrem, JL; Rabinowicz, AL; Subramanian, I | 1 |
| Christensen, H; Jorm, AF; Lux, O; Naidoo, D; Parslow, RA; Sachdev, PS; Salonikas, C; Wen, W | 1 |
| Barutcu, I; Esen, AM; Gullu, H; Ozdemir, R; Sezgin, AT; Sezgin, N; Topal, E | 1 |
| Also-Rallo, E; Balcells, S; Grinberg, D; Lailla, JM; Lopez-Quesada, E; Urreizti, R; Vilaseca, MA | 1 |
| Abbate, R; Alessandrello Liotta, A; Berloco, P; Cellai, AP; Leprini, E; Marcucci, R; Pagnini, P; Prisco, D; Rogolino, A | 1 |
| Hultberg, B | 1 |
| Amato, S; Bottini, F; Calevo, MG; Cerone, R; Minniti, G; Molinari, AC; Perutelli, P | 1 |
| Andria, G; Scala, I; Sebastio, G | 1 |
| Cesari, M; Pessina, AC; Rossi, GP; Sticchi, D | 1 |
| Aydin, S; Curgunlu, A; Erdine, S; Ertürk, N; Karter, Y; Kutlu, A; Oztürk, E; Simsek, G; Uzun, H; Vehid, S | 1 |
| Benetin, J; Blazícek, P; Gmitterová, K; Kukumberg, P; Valkovic, P; Valkovicová, L | 1 |
| Allen, RH; Brown, TR; DeCarli, C; Paik, MC; Sacco, RL; Stabler, SP; Wright, CB | 1 |
| Bourdon, E; Delabar, JM; Delcayre, C; Friguet, B; Janel, N; Nehmé, J; Pivert, G; Robert, K | 1 |
| Harma, M; Kocyigit, A | 1 |
| Cucinelli, F; Lanzone, A; Mele, C; Panunzi, S; Perri, C; Ranieri, M; Suriano, R; Villa, P | 1 |
| Fan, DS; Shen, Y; Sun, AP; Wang, HL; Yang, YJ; Zhang, J | 1 |
| Joseph, T; Muntzel, MS; Onwumere, O | 1 |
| Franzon, R; Stefanello, FM; Tagliari, B; Wajner, M; Wannmacher, C; Wyse, AT | 1 |
| Ahsan, H; Factor-Litvak, P; Gamble, MV; Graziano, JH; Ilievski, V; Liu, X; Parvez, F; Slavkovich, V | 1 |
| Stammler, F | 1 |
| Bencze, J; Préda, I; Vargova, K | 1 |
| Mahmood, A; Mahy, G; Mainwaring, J; Needham, J; Prosser, J; Ramage, J; Trebble, T | 1 |
| Battler, A; Harell, D; Koren-Morag, N; Mager, A; Shohat, M | 1 |
| Cattaneo, M; De Franchis, R; Formenti, S; Lecchi, A; Meucci, G; Rondonotti, E; Saibeni, S; Tagliabue, L; Vecchi, M | 1 |
| Bayerlein, K; Bleich, S; Hillemacher, T; Kornhuber, J; Mugele, B; Reulbach, U; Sperling, W | 1 |
| Kinalska, I; Kowalska, I; Rudy, A; Straczkowski, M | 1 |
| Bakan, E; Becit, N; Keleş, S; Koçak, H; Koçoğullari, CU; Unlü, Y | 1 |
| Ward, RA | 1 |
| Blasco, C; Caballería, J; Deulofeu, R; Gual, A; Lligoña, A; Lluis, JM; Parés, A; Rodés, J | 1 |
| Bauer, DC; Jamal, SA; Leiter, RE | 1 |
| Burnett, JR; Gillett, MJ | 1 |
| Arteaga-Vizcaíno, M; Diez-Ewald, M; Fernández, G; Fernández, M; Fernández, N; Narváez, J; Torres, E; Vizcaíno, G | 1 |
| Ayaz, S; Riza Erbay, A; Sahin, O; Sasmaz, H; Senen, K; Turhan, H; Yasar, AS; Yetkin, E | 1 |
| Gottsäter, A; Hultberg, B; Jonasson, T; Ohlin, AK; Ohlin, H | 1 |
| Favilla, S; Ghiadoni, L; Pinto, S; Salvetti, A; Salvetti, G; Taddei, S; Versari, D; Virdis, A | 1 |
| Abouzahir, A; Baigts, F; Bauduceau, B; Bordier, L; Burnat, P; Dupuy, O; Garcin, JM; Gardet, V; Mayaudon, H | 1 |
| Biagio Mercuri, N; De Sarro, G; Ferreri Ibbadu, G; Gallelli, L; Mancuso, F; Siniscalchi, A | 1 |
| Atar, I; Atar, IA; Aydinalp, A; Bozbaş, H; Demircan, S; Korkmaz, ME; Müderrisoğlu, H; Ozin, B; Yildirir, A | 1 |
| Bostantjopoulou, S; Frangia, T; Hatzizisi, O; Katsarou, Z; Kazis, A; Kiosseoglou, G; Kyriazis, G; Papazisis, K | 1 |
| Lominadze, D; Roberts, AM; Tyagi, SC | 1 |
| Fowler, B | 1 |
| de Groot, LC; Verhoef, P | 1 |
| Blom, HJ; den Heijer, M; Gellekink, H; Heil, SG | 1 |
| Dierkes, J; Westphal, S | 1 |
| McDowell, IF; Moat, SJ | 1 |
| Lentz, SR; Wilson, KM | 1 |
| Cotter, A; Daly, S; Molloy, AE; Scott, J | 1 |
| Rosenberg, I; Troen, A | 1 |
| Alvarez González, A; Delgado, P; Hernández, D; Lorenzo, V; Pérez Tamajón, L; Sánchez Alvarez, JE | 1 |
| Fernández-Ballart, J; Joven, J; Labad, A; Martorell, L; Murphy, M; Simó, JM; Valero, J; Vilella, E; Virgos, C | 1 |
| Seftel, AD | 1 |
| Branzi, A; Carigi, S; Coccolo, F; Grigioni, F; Kessels, K; Koessels, K; Magelli, C; Magnani, G; Marrozzini, C; Marzocchi, A; Musuraca, AC; Ortolani, P; Potena, L; Russo, A; Sassi, S | 1 |
| Frick, B; Fuchs, D; Schennach, H; Schroecksnadel, K; Winkler, C; Wirleitner, B | 1 |
| Lentz, SR | 3 |
| Sachdev, PS | 1 |
| Avdelidou, A; Demitriadis, A; Destanis, E; Economou, H; Grekas, D; Makedou, A; Theodoridou, A; Tourkantonis, A | 1 |
| Bottiglieri, T | 1 |
| Díez, N; Hurtado, V; Pérez, R; Santidrián, S | 1 |
| Chang, JM; Chen, HC; Chiu, YW; Chuang, HY; Hwang, SJ; Kuo, HT; Lai, YH; Tsai, JC | 1 |
| Henderson, B; Joshua, IG; Moshal, KS; Ovechkin, AV; Roberts, AM; Rodriguez, W; Steed, M; Tyagi, N; Tyagi, SC | 1 |
| Doherty, GH; Foister, NS; Mackie, JB; Oldreive, CE | 1 |
| Cangemi, R; D'Angelo, A; Di Lecce, VN; Fimognari, FL; Loffredo, L; Mazzola, G; Sampietro, F; Sbrighi, PS; Violi, F | 1 |
| Bottiglieri, T; Diaz-Arrastia, R | 1 |
| Bunout, D; Hirsch, S | 1 |
| Ahmed, F; Azfar, F; Zaidi, MS | 1 |
| Basar, N; Bicer, A; Erbay, AR; Sahin, O; Turhan, H; Yasar, AS; Yetkin, E | 1 |
| Adachi, T; Horiuchi, M; Kobayashi, K; Nagai, Y; Nakashima, Y; Nihei, S; Suzuka, H; Tasaki, H; Yamashita, K | 1 |
| Pfanzagl, B | 1 |
| Chen, KJ; Lin, BF; Pan, WH; Shaw, NS; Wei, IL; Yang, FL | 1 |
| Dagnelie, PC; Garcia, AL; Hoffmann, I; Katz, N; Koebnick, C; Leitzmann, C; Lindemans, J; Strassner, C | 1 |
| Chen, J; Li, M; Liao, YH; Shu, YW | 1 |
| Bouzouf, M; Guerrero, JM; Martinez-Cruz, F; Molinero, P; Osuna, C | 1 |
| Akar, N; Ozdemir, F; Tekeli, O; Turaçli, ME | 1 |
| Chen, JH; Hashmi, A; Kuo, HK; Lipsitz, LA; Milberg, WP; Sorond, FA | 1 |
| Scott, PM | 1 |
| Chauhan, AK; Dole, VS; Handy, DE; Kamath, AF; Kisucka, J; Loscalzo, J; Wagner, DD | 1 |
| Ausserer, B; Graninger, G; Hubmann, M; Huemer, C; Huemer, M; Schlachter, K; Simma, B; Tscharre, A; Ulmer, H | 1 |
| Blom, HJ; Boers, GH; Riksen, NP; Rongen, GA; Smits, P | 1 |
| Acanfora, F; Capasso, R; Ingrosso, D; Lombardi, C; Perna, AF; Satta, E | 1 |
| Cibulka, R; Eiselt, J; Filipovský, J; Racek, J; Rajdl, D; Rusnáková, H; Siroká, R; Trefil, L | 1 |
| Itaya, Y; Suzuki, H; Takenaka, T | 1 |
| Baltar, VT; Batlouni, M; Bertolami, MC; Gravina-Taddei, CF; Salvarini, NA; Sarteschi, C; Sousa, JE | 1 |
| Fields, MC; Levine, SR | 1 |
| Bryan, RM; Durante, W; Jiang, X; Liao, D; Randhawa, JK; Rumbaut, RE; Schafer, AI; Tan, H; Wang, H; Yang, F; Yang, X | 1 |
| Bailey, LB | 1 |
| Hu, R; Lau, CP; Tse, HF; Wang, WQ; Zhang, XX | 1 |
| Clarke, R; Lewington, S | 1 |
| Sun, W; Wang, G; Wang, X; Zeng, XK; Zhang, ZM | 1 |
| Durante, W; Jiang, X; Li, Z; Liao, D; Magera, MJ; Tan, H; Trial, J; Wang, H; Yang, F; Yang, X | 1 |
| Borgiel-Marek, H; Gatnar, A; Gnot, R; Januła, A; Kajdaniuk, D; Kos-Kudła, B; Marek, B; Sierek, K; Strzyzewski, A; Wyrwas-Bełz, U; Zeka, G | 1 |
| Chen, TW; Lin, CC; Tai, HC; Yang, WC | 1 |
| Casis Herce, B; Fernández-Miranda, C; Gómez de la Cámara, A; Gómez González, P; Martínez López, J; Martínez Prieto, M; Sáenz-López Pérez, S; Sánchez Gómez, F | 1 |
| Fan, YH; Lam, WW; Liang, KS; Mok, V; Wong, A; Wong, KS | 1 |
| Chai, H; Chen, C; Lin, PH; Mu, H; Ohashi, R; Yan, S; Yao, Q | 1 |
| Frick, B; Fuchs, D; Fuith, LC; Schroecksnadel, K; Winkler, C | 1 |
| Iwamoto, J; Kanoko, T; Sato, Y; Satoh, K | 1 |
| Corvisier, JM; Dorval, I; Geffroy, F; Lellouche, F; Rouaut, G | 1 |
| Chiariello, M; De Luca, G; Gregorio, G; Lange, H; Suryapranata, H | 1 |
| Fortmann, SP; Gaziano, JM; Goldfarb, DS; Haroldson, JA; Hartigan, P; Jamison, RL; Kaufman, J; Lavori, P; McCully, KS; Robinson, K | 1 |
| Barberis, G; Drenkard, C; Gamron, S; Menso, E; Onetti, CM; Onetti, L; Villafañe, S | 2 |
| Rafflenbeul, W | 1 |
| Bamford, L; Chakravarthy, U; Gilchrist, SE; Graydon, R; Hughes, AE; McGibbon, D; McGimpsey, SJ; McKeeman, GC; O'Reilly, D; Patterson, CC; Woodside, JV; Young, IS | 1 |
| Bouter, LM; Dekker, JM; Heine, RJ; Nijpels, G; Smulders, YM; Spoelstra-De Man, AM; Stehouwer, CD | 1 |
| Aksoy, Y; Turhan, H; Yetkin, E | 1 |
| Brozek, J; Szczeklik, A; Undas, A | 1 |
| Acres, JM; Almeida, OP; Flicker, L; Hankey, GJ; Jamrozik, K; Norman, P; Thomas, J; Vasikaran, SD | 1 |
| Gunenc, Z; Karabulut, E; Onalan, G; Onalan, R | 1 |
| Aksoy, Y; Kosar, F; Ozerol, I; Sincer, I | 1 |
| Giannoulia-Karantana, A; Papaconstantinou, ED; Schulpis, KH; Tjamouranis, I; Tsakiris, S; Tsakiris, T | 1 |
| Alvestrand, A; Anderstam, B; Sjöberg, B; Suliman, M | 1 |
| Chu, NF | 1 |
| Hekimsoy, Z; Ozmen, B; Ulusoy, S | 1 |
| Ai, L; Lin, JS; Sun, XM; Tang, WX; Yuan, SY; Zhang, WY; Zhou, XM | 1 |
| Chuy, E; Díaz, JM; Facundo, C; Gich, I; Guirado, LL; Montañés, R; Oliver, A; Puig, T; Sainz, Z; Solà, R | 1 |
| Diáz, A; Errasti, P; Gavira, JJ; Hernández, A; Manrique, J; Pujante, D | 1 |
| Chuy, E; Díaz, JM; Gich, I; Guirado, LL; Montañés, R; Oliver, A; Puig, T; Sainz, Z; Solà, R | 1 |
| Araki, R; Igarashi, S; Maruyama, C; Maruyama, T; Satoh, T; Umegaki, K; Yoshida, M | 1 |
| Brancato, R; D'Angelo, A; Fattorini, A; Lattanzio, R; Ramoni, A; Sampietro, F | 1 |
| Chan, JB; Chen, CP; Eikelboom, JW; Hankey, GJ; Ho, GY; Tan, SL; Wong, CR | 1 |
| Mallamaci, F; Zoccali, C | 1 |
| Chalopin, JM; Devillard, N; Ducloux, D; Kazory, A; Klein, A | 1 |
| Bárány, P; Lindholm, B; Rashid Qureshi, A; Stenvinkel, P; Suliman, ME | 1 |
| Babushkin, I; Belmaker, RH; Bersudsky, Y; Levine, J; Osher, Y; Ruderman, V; Sela, BA; Shumaico, O; Stahl, Z | 1 |
| Eichinger, S | 1 |
| den Heijer, M | 1 |
| Brahmachari, V; Mahajan, A; Sengupta, S; Senthilkumar, RD; Sharma, A; Sharma, P; Sundaramoorthy, E | 1 |
| Díaz, ML; Forrester, M; Freixas, E; Schropp, J; Trimarchi, H; Young, P | 1 |
| Fowler, B; Koch, HG; Lagler, F; Linnebank, M; Muntau, AC; Olgemöller, B; Röschinger, W | 1 |
| Bolek, L; Cífková, R; Dolejsová, M; Filipovský, J; Mayer, O; Simon, J | 1 |
| Cipriani, F; Durigon, E; Matté, C; Stefanello, FM; Wajner, M; Wyse, AT | 1 |
| Chiarello, PG; Cuppari, L; Draibe, SA; Feiten, SF; Nerbass, FB; Vannucchi, H | 1 |
| Shah, DI; Singh, M | 2 |
| Angelini, GD; Jeremy, JY; Jones, RA; Koupparis, A; Persad, R; Shukla, N | 1 |
| Bandarian, F; Fakhrzadeh, H; Ghotbi, S; Heshmat, R; Larijani, B; Nouri, M; Pourebrahim, R; Shafaee, A | 1 |
| Yeh, SM; Yeh, YY | 1 |
| Allami, A; Bendriss, A; Benjouad, A; Benkouka, F; Bennouar, N; Benomar, A; Benomar, M; Carrié, A; Coiffard, AS; Fellati, S; Guedira, A; Kadiri, N; Laraqui, A; Raisonnier, A; Srairi, JE | 1 |
| Creatsas, G; Economou, EV; Kouskouni, EE; Magaziotou-Elefsinioti, I; Malamitsi-Puchner, AV; Pitsavos, CP | 1 |
| Hoffman, M; Lenkowski, A; Lockhart, E; Sauls, DL; Warren, ME; Wilhelm, SE | 1 |
| O, K; Siow, YL; Woo, CW | 1 |
| Blom, HJ; Borm, GF; den Heijer, M; Keijzer, MB; Verhoef, P | 1 |
| Carosi, G; Cologni, G; Costarelli, S; Labate, L; Lapadula, G; Moretti, F; Quiros-Roldan, E; Tirelli, V; Torti, C; Uccelli, MC | 1 |
| Bayram, C; Bekpinar, S; Cetin, O; Turkmen, A; Ulutin, T; Unlucerci, Y | 1 |
| Guthikonda, S; Haynes, WG | 1 |
| Lominadze, D; Moshal, KS; Ovechkin, AV; Tyagi, N; Tyagi, SC | 1 |
| Jacobsen, DW | 1 |
| Loscalzo, J | 3 |
| Netto, CA; Salbego, CG; Tagliari, B; Wyse, AT; Zamin, LL | 1 |
| Lawson-Yuen, A; Levy, HL | 1 |
| Aksoy, M; Ayalp, K; Baktiroglu, S; Basar, Y; Dilege, S; Genc, FA; Kayabali, M; Kurtoglu, M; Salmayenli, N | 1 |
| Abbate, R; Biagini, MR; Capanni, M; Ceni, E; Fedi, S; Galli, A; Manta, R; Marcucci, R; Milani, S; Paniccia, R; Surrenti, C; Tozzi, A | 1 |
| Brozek, J; Jakubowski, H; Jankowski, M; Siudak, Z; Szczeklik, A; Undas, A | 1 |
| Camps, J; Fernández-Ballart, J; Ferré, N; Joven, J; Mackness, B; Mackness, M; Marsillach, J; Murphy, MM | 1 |
| Cook, S; Hess, OM | 1 |
| Aznar, J; Calvo, J; Corella, D; España, F; Estellés, A; Ricart, JM; Santaolaria, M; Todolí, J; Vayá, A; Villa, P | 1 |
| Colaizzo, D; Croce, AI; Grandone, E; Margaglione, M; Notarangelo, A; Sciannamè, N; Vecchione, G | 1 |
| Blom, HJ; Castro, R; Jakobs, C; Rivera, I; Tavares de Almeida, I | 1 |
| Lucchesi, PA; Rezk, B; Rocic, P | 1 |
| Burlina, A; Cesari, M; Maiolino, G; Pedon, L; Pessina, AC; Rossi, GP; Seccia, TM; Sticchi, D; Zanchetta, M; Zavattiero, S | 1 |
| Bydlowski, SP; Chagas, AC; Chamone, DA; da Luz, PL; Faria-Neto, JR; Lemos Neto, PA; Ramirez, JA | 1 |
| Huber, K; Jordanova, N; Maurer, G; Niessner, A; Nikfardjam, M; Schreiber, W; Speidl, WS; Wojta, J; Zeiner, A; Zorn, G | 1 |
| Chen, FY; Chen, L; Feng, XH; Gao, W; Guo, YH; Tang, CS | 1 |
| Akilzhanova, A; Aoyagi, K; Karazhanova, L; Takamura, N; Yamashita, S; Zhaojia, Y | 1 |
| Bieglmayer, C; Koppensteiner, R; Minar, E; Plank, C; Schernthaner, G; Schernthaner, GH | 1 |
| Chen, L; Li, N; Li, PL; Muh, RW | 1 |
| Nakajima, K | 1 |
| Djukanovic, L; Jemcov, T; Novakovic, I; Pejanovic, S; Radovic, M; Simic-Ogrizovic, S; Stosovic, M | 1 |
| Bernasconi, AR; Del Pino, N; Heguilén, RM; Liste, A; Rosa Diez, GJ | 1 |
| Behari, M; Biswas, A; Chatterjee, T; Choudhry, PV; Panigrahi, I; Saxena, R | 1 |
| Baudo, F; Campolo, J; Caruso, R; Cighetti, G; De Chiara, B; Dellanoce, C; Parodi, O; Parolini, M; Sedda, V; Tonini, A | 1 |
| Alessi, E; Antico, A; Cucinotta, D; Di Benedetto, A; Di Cesare, E; Ientile, R; La Scala, R; Nicocia, G; Raimondo, G; Russo, GT | 1 |
| Lena, KB; Pai, GP; Rajadhyaksha, VD; Sali, N; Shaikh, AA; Shenoy, KT; Shenoy, ST; Syam, S | 1 |
| Bayerlein, K; Bleich, S; Degner, D; Frieling, H; Hillemacher, T; Kornhuber, J | 1 |
| Fillet, M; Li, N; Li, PL; Muh, RW; Renert, AF; Yi, F; Zhang, AY | 1 |
| Arvanitidou, M; Makedou, A; Mavromichalis, I; Papandreou, D; Rousso, I | 1 |
| Bell, RJ; Davis, SR; Shah, S | 1 |
| Bjelland, I; Gjesdal, CG; Nurk, E; Nygård, O; Refsum, H; Smith, AD; Tell, GS; Tverdal, A; Ueland, PM; Vollset, SE | 1 |
| Addad, F; Chauffert, M; Chevenne, D; Farhat, MB; Gerhardt, M; Kerkeni, M; Maaroufi, K; Miled, A; Myara, A; Trivin, F | 1 |
| Boerwinkle, E; de Andrade, M; Ding, K; Kardia, SL; Kullo, IJ; Mosley, TH; Turner, ST | 1 |
| Hasiripi, H; Karakurt, A; Saricaoglu, MS; Sengun, A | 1 |
| Angelova, EA; Atanasova, PA; Minkova, GD; Semerdjieva, MA; Tzvetkova, TZ | 1 |
| Chan, MT; Forbes, A; Leslie, K; Myles, PS; Paech, M; Peyton, P | 2 |
| Karasu, E; Ozdem, S; Sadan, G; Tasatargil, A | 1 |
| Engedal, K; Laake, K; Landaas, S; Lyberg, T; Raeder, S | 1 |
| Thompson, J | 1 |
| Barcikowska, M; Chodakowska-Zebrowska, M; Czyzewski, K; Lokk, J; Peplonska, B; Religa, D; Stepien, K; Styczynska, M; Winblad, B | 1 |
| Athanassious, CN; Lentz, SR; Mullick, AE; Rutledge, JC; Symons, JD; Zaid, UB | 1 |
| Camicioli, R; Espay, AJ; Lafontaine, AL; Lang, AE; Martin, WR; Postuma, RB; Ranawaya, R; Suchowersky, O; Zadikoff, C | 1 |
| Kes, P; Lovcić, V; Reiner, Z | 1 |
| Green, TJ; Knight, RG; Mann, JI; McMahon, JA; Skeaff, CM; Williams, SM | 1 |
| Kim, DJ; Kim, GS; Kim, HH; Kim, YS; Koh, JM; Lee, KU; Lee, YS; Park, JY | 1 |
| Lominadze, D; Moshal, KS; Ovechkin, AV; Sen, U; Steed, MM; Tyagi, N; Tyagi, SC | 1 |
| Naushad, SM; Prasad, KC; Radha Rama Devi, A | 1 |
| Aléssio, AC; Annichino-Bizzacchi, JM; Bydlowski, SP; Höehr, NF; Siqueira, LH | 1 |
| Akoglu, B; Caspary, WF; Faust, D; Wondra, K | 1 |
| Almawi, WY; Aouni, Z; Chaieb, A; Chaieb, M; Ezzidi, I; Mahjoub, T; Marmouche, H; Mtiraoui, N; Vaxillaire, M | 1 |
| Björck, J; Hellgren, M; Lindblad, U; Råstam, L | 1 |
| Defazio, G; Lamberti, P; Livrea, P; Martino, D; Zoccolella, S | 1 |
| Elmadfa, I; Genser, D; Halbmayer, WM; Hauer, R; Mlczoch, J; Prachar, H | 1 |
| Chernikova, IV; Kostiuchenko, GI; Kostiuchenko, LA; Kulikov, VP | 1 |
| Battezzati, A; Bertoli, S; San Romerio, A; Testolin, G | 1 |
| Jordao, AA; Meirelles, MS; Melo, SS; Persuhn, DC; Vannucchi, H | 1 |
| Kozłowska, I | 1 |
| Carlsson, CM | 1 |
| Clement, CI; Goldberg, I | 1 |
| Gaĭgaĭlaĭte, V; Sabaliauskene, Z | 1 |
| Evert, BO; Jakobs, C; Jarre, E; Klockgether, T; Kunz, WS; Linnebank, M; Lutz, H; Noelker, C; Struys, E; Vielhaber, S; Wüllner, U | 1 |
| Henderson, B; Moshal, KS; Rosenberger, DS; Sen, U; Singh, M; Tyagi, N; Tyagi, SC; Zhang, H | 1 |
| Badiou, S; Canaud, B; Cristol, JP; Delcourt, C; Dupuy, AM; Jaussent, I; Leray-Moragues, H; Maurice, F; Naudin, E; Rivory, JP; Terrier, N | 1 |
| Chan, C; Ji, C; Kaplowitz, N | 1 |
| Fukada, S; Kawagishi, H; Morita, T; Sekiya, A; Sugiyama, K | 1 |
| Deulofeu, R; Doreste, J; Fiuza, MD; Henríquez, P; Serra-Majem, L | 1 |
| Cacoub, P; Limal, N; Piette, JC; Scheuermaier, K; Sene, D; Tazi, Z | 1 |
| Ferrannini, E; Nannipieri, M; Santini, E; Solini, A | 1 |
| Assanelli, D; Grassi, M; Pezzini, A | 1 |
| Bouzid, C; Essais, O; Ibrahim, H; Machghoul, S; Ouertani, H; Ouni, Z; Zidi, B | 1 |
| Ghosh, K | 1 |
| Abdella, NA; Al Humood, S; Al Wazzan, H; Marouf, R; Mojiminiyi, OA; Qurtom, M; Zubaid, M | 1 |
| Chan, L; Durante, W; Gaubatz, J; Hui, R; Jiang, X; Li, Z; Liao, D; Pownall, HJ; Schafer, AI; Tan, H; Wang, H; Yang, F; Yang, X | 1 |
| Hankey, GJ | 1 |
| Kes, P; Kusec, V; Lovcić, V; Zeljko, R | 1 |
| Munakata, M; Tayama, J; Toyota, T; Yoshinaga, K | 1 |
| Goutzioulis, M; Hitoglou, A; Kalogiannidis, I; Makedos, A; Makedos, G; Papanicolaou, A; Vrazioti, V | 1 |
| Glowacki, R; Jakubowski, H; Stepień, E; Tisończyk, J; Tracz, W; Undas, A | 1 |
| Cho, SE; Chung, WS; Hong, KS; Shin, GJ | 1 |
| Blom, HJ; Bos, GM; Cattaneo, M; den Heijer, M; Eichinger, S; Gerrits, WB; Rosendaal, FR; Willems, HP | 1 |
| Aminzadeh, MA; Golbahar, J; Kassab, SE; Omrani, GR | 1 |
| Bozzini, C; Corrocher, R; Faccini, G; Friso, S; Girelli, D; Guarini, P; Martinelli, N; Olivieri, O; Pizzolo, F; Trabetti, E | 1 |
| Imren, E; Ozkan, Y; Simşek, B; Torun, M; Yardim-Akaydin, S | 1 |
| Allen, JC; Arnold, EK; Bell, CW; Hoffman, M; Sauls, DL | 1 |
| Elmadfa, I; Genser, D; Majchrzak, D; Männer, M; Rust, P; Singer, I; Wagner, KH | 1 |
| Darvish, S; Davoodi, G; Fallah, N; Fallahi, F; Karimi, A; Mahmoodian, M; Sadeghian, S; Salarifar, M | 1 |
| Blom, HJ; Borm, GF; den Heijer, M; Hermus, AR; Keijzer, MB; Ueland, PM; Vollset, SE | 1 |
| Lucca, U; Quadri, P; Tettamanti, M | 1 |
| Pietrzik, K | 1 |
| Cottin, Y; Duvillard, L; Gambert, P; Guilland, JC; Korandji, C; Moreau, D; Rochette, L; Sicard, P; Vergely, C; Zeller, M | 1 |
| Feki, H; Feki, M; Ghorbel, IB; Houman, H; Kaabachi, N; Omar, S; Souissi, M | 1 |
| Antoniades, C; Bouras, G; Marinou, K; Pitsavos, C; Stefanadis, C; Tentolouris, C; Tousoulis, D; Vasiliadou, C | 1 |
| Cattaneo, M | 5 |
| Candito, E; Candito, M; Chatel, M; Dunac, A; van Obberghen, E | 1 |
| Boughanem, N; Leemann, B; Schnider, A | 1 |
| Delabar, JM; Demuth, K; Hamelet, J; Janel, N; Paul, JL | 1 |
| Brenner, B; Hoffman, R; Nadir, Y | 1 |
| Clarke, ZL; Lang, D; Lewis, MJ; Miller, AL; Moat, SJ; Randall, MD | 1 |
| Chang, L; Dai, J; Li, W; Tang, C; Wang, N; Wang, X; Zhang, Z; Zhu, Y | 1 |
| Hart, SR; Jackson, SH; Mangoni, AA; Swift, CG | 1 |
| Chaiyasoot, W; Chanchairujira, T; Leowattana, W; Ong-ajyooth, L; Ong-ajyooth, S; Shayakul, C; Sritippayawan, S; Tungkasereerak, P; Vareesangthip, K; Vasuvattakul, S | 1 |
| Balogh, E; Bereczky, Z; Boda, K; Császár, A; Czuriga, I; Edes, I; Ferdinandy, P; Kónya, C; Koszegi, Z; Muszbek, L | 1 |
| Lucock, MD | 1 |
| Födinger, M; Hubmann, M; Huemer, M; Krumpholz, R; Simma, B; Ulmer, H; Vonblon, K | 1 |
| Guldener, CV; Stehouwer, CDA | 1 |
| Bartelings, MM; de Jonge, R; Gittenberger-de Groot, AC; Helbing, WA; Lindemans, J; Ottenkamp, J; Siebel, FM; Steegers, EA; Steegers-Theunissen, RP; Ursem, NT; Verkleij-Hagoort, AC; Verlinde, M | 1 |
| Arning, E; Austin, RC; Bottiglieri, T; Lentz, SR; Leo, L; Lhoták, S; McCaw, RB; Wilson, KM | 1 |
| Alvim, TC; Cardoso, J; Carvalho, Md; Dusse, LM; Fernandes, AP; Franco, Hde A; Franco, RM; Guimarães, DA; Teixeira, Gda S | 1 |
| Calzavara Pinton, PG; Girolomoni, G; Gisondi, P; Malerba, M; Radaeli, A; Sala, R | 1 |
| Chow, G; Mattie, M; Yazaki, Y | 1 |
| Rosenson, RS; Tangney, CC | 1 |
| de Jonge, R; de Vries, JH; Hop, WC; Steegers-Theunissen, RP; Ursem, NT; Verkleij-Hagoort, AC | 1 |
| Emmelot-Vonk, M; Grobbee, DE; Muller, M; Nakhai Pour, HR; van der Schouw, YT | 1 |
| Angayarkanni, N; Lakshmi, S; Ramakrishnan, S; Selvi, R; Sulochana, KN | 1 |
| Argun, L; Calýpkan, S; Comlekçi, A; Demir, O; Demir, T; Esen, A; Gülcü, A; Seçil, M; Yepil, S | 1 |
| Dudczak, R; Graf, S; Huber, K; Khorsand, A; Kletter, K; Maurer, G; Nekolla, S; Nikfardjam, M; Ofluoglu, S; Pirich, C | 1 |
| de Bree, A; de Deckere, E; Jacobs, RG; van den Berg, H; van der Put, NM; van Vliet, T | 1 |
| Bianchin, M; Chiappelli, M; Forti, P; Licastro, F; Maioli, F; Montesi, F; Patterson, C; Ravaglia, G | 1 |
| Asthana, S; Bofkin, KA; Evans, C; Halazun, KJ; Henderson, M; Spark, JI | 1 |
| Latella, C; Lombardo, VT; Luise, F; Mammi, C; Occhiuto, A; Oriana, V; Piromalli, A; Ramirez, F; Sottilotta, G | 1 |
| Areekul, S; Atamasirikul, K; Cheeramakara, C; Chotsuppakarn, S; Chuansumrit, A; Sirachainan, N; Tapanapruksakul, P; Visudtibhan, A | 1 |
| Hansrani, M; Oates, C; Stansby, G | 1 |
| Chen, YL; Guo, MH; Huang, JX; Lin, RJ; Zhang, Y | 1 |
| Chambers, S; Fraser, R; George, P; Lever, M; McEntyre, C; Slow, S; Vasudevamurthy, M | 1 |
| Brouwer, JL; Lijfering, WM; van de Poel, MH; van der Meer, J; Veeger, NJ | 1 |
| Ayabakan, H; Baran, F; Kalaslioglu, V; Sarican, T; Turkmen, S; Yenice, N | 1 |
| Bozzini, C; Corrocher, R; Faccini, G; Friso, S; Girelli, D; Guarini, P; Lotto, V; Martinelli, N; Mazzucco, A; Olivieri, O; Pignatti, PF; Pizzolo, F; Tenuti, I; Trabetti, E; Villa, G | 1 |
| Austin, RC; Colgan, SM | 1 |
| Bini, T; Bongiovanni, M; Casana, M; Cicconi, P; Monforte, Ad; Pisacreta, M; Ranieri, R; Russo, U; Tordato, F | 1 |
| Hintze, TH; Kinugawa, S; Koller, A; Ojaimi, C; Recchia, FA; Suematsu, N; Wang, Z; Xu, X | 1 |
| Brandsch, C; Dinger, C; Eder, K; Hirche, F; Stangl, GI; Weisse, K | 1 |
| Pandey, SN; Talwalkar, S; Vaidya, AD; Vaidya, RA | 1 |
| Deshpande, JA; Deshpande, SS; Deshpande, VU; Farrant, H; Ganpule, AA; Joshi, NP; Lubree, HG; Naik, SS; Ramdas, LV; Refsum, H; Thuse, NV; Uradey, BS; Yajnik, CS | 1 |
| Chiolero, A; Faeh, D; Paccaud, F | 1 |
| Hao, L; Li, Z; Ma, J; Stampfer, MJ; Tian, Y; Willett, WC; Zhu, J | 1 |
| Henninger, N; Krause, M; Okun, JG; Schwab, S; Wang, Q | 1 |
| Guéant, JL; Peyrin-Biroulet, L; Roblin, X | 1 |
| Denz, HA; Fiegl, M; Frick, B; Fuchs, D; Schroecksnadel, K; Winkler, C | 1 |
| Engin, B; Ozkan, Y; Sepici, A; Sepici, V; Simşek, B; Yardim-Akaydin, S | 1 |
| Alberto, JM; Blaise, SA; Bossenmeyer-Pourié, C; Daval, JL; Guéant, JL; Nédélec, E; Schroeder, H | 1 |
| Herrmann, M; Herrmann, W; Obeid, R | 1 |
| Corrocher, R; Faccini, G; Friso, S; Girelli, D; Guarini, P; Martinelli, N; Olivieri, O; Pavan, C; Pizzolo, F | 1 |
| Jakubowski, H; Perła-Kaján, J; Twardowski, T | 1 |
| Anai, M; Anan, F; Chiba, S; Gotoh, K; Higuchi, K; Kakuma, T; Katsuragi, I; Masaki, T; Tanaka, K; Tsubone, T; Yoshimatsu, H | 1 |
| Dairou, J; Delabar, JM; Demuth, K; Dupret, JM; Hamelet, J; Janel, N; Ledru, A; Paul, JL; Rodrigues-Lima, F | 1 |
| Leonova, SF; Shirokov, EA | 1 |
| Fu, M; Haugen, E; Kondziella, D; Zetterberg, H | 1 |
| Abe, Y; Aoyagi, K; Kadota, K; Kusano, Y; Maeda, T; Morishita, Y; Nagazumi, T; Nakazato, M; Takamura, N; Yagura, C | 1 |
| Castañon, MM; Kordich, L; Lauricella, AM; Quintana, I | 1 |
| Belardinelli, R; Caramia, G | 1 |
| Abu-Hijleh, M; Garadah, T; Golbahar, J; Gumaa, K; Kassab, S; Senok, S; Wazir, J | 1 |
| Alvares Delfino, VD; Barbosa, DS; de Andrade Vianna, AC; Matsuo, T; Mise, RA; Mocelin, AJ | 1 |
| Boers, GH; Chwatko, G; Jakubowski, H; Shih, DM; Strauss, KA | 1 |
| Komaroff, AL | 1 |
| Blandini, F; Martignoni, E; Nappi, G; Pacchetti, C; Tassorelli, C; Zangaglia, R | 1 |
| Blom, HJ; Boers, GH; Heil, SG; Riksen, NP; Smulders, Y | 1 |
| Bigard, MA; Bronowicki, JP; Chamaillard, M; Desreumaux, P; Guéant, JL; Peyrin-Biroulet, L; Rodriguez-Guéant, RM; Xia, B | 1 |
| Chen, BC; Chen, CW; Lin, CL; Lin, CT; Lin, TK; Lin, YL | 1 |
| Bala, E; Heur, M; Kosmorsky, GS; Peachey, NS | 1 |
| Ballard, C; Dickinson, HO; Kalaria, R; Kenny, RA; Rowan, EN; Stephens, S | 1 |
| Bottiglieri, T; Cross, JC; Elmore, CL; Gravel, RA; Krupenko, NI; Krupenko, SA; Leclerc, D; Matthews, RG; Rozen, R; Watson, ED; Wu, X | 1 |
| Carvalho, Md; da Fonseca Neto, CP; Fernandes, AP; Garcia, JC; Lima, LM; Loures-Vale, AA; Saad, JA; Sabino, Ade P; Sousa, MO | 1 |
| Badrinath, VS; Karunakaran, C; Narayanasamy, A; Ranganathan, P; Roy, J; Sharma, T; Sivaramakrishnan, R; Subramaniam, B | 1 |
| Chen, QZ; dos Santos, EA; Li, N; Li, PL; Xia, M; Yi, F | 1 |
| Goto, Y; Hamajima, N; Ishida, Y; Itou, S; Kawai, S; Kondo, T; Naito, M; Nishio, K | 1 |
| Blom, HJ; den Heijer, M; Graafsma, SJ; Hermus, AR; Kranendonk, SE; Peeters, AC; van Landeghem, BA | 1 |
| Bleich, S; Frieling, H; Hillemacher, T; Kornhuber, J; von Ahsen, N; Wilhelm, J | 1 |
| Barrantes-Santamaría, M; Holst-Schumacher, I; Monge-Rojas, R | 1 |
| Gatt, A; Makris, M | 1 |
| Chang, L; Dai, J; Guan, Y; Li, W; Wang, X; Zhang, Z | 1 |
| Bendini, MG; Cozzari, L; De Cristofaro, R; Farina, SM; Giordano, A; Giordano, G; Lanza, GA; Leggio, M; Mazza, A; Menichini, G; Moriconi, E | 1 |
| Anastasio, R; Casuccio, A; Ciaccio, M; Cigna, V; Coco, LL; Malato, A; Siragusa, S | 1 |
| Jakubowski, H; Kaján, L; Marczak, Ł; Perła-Kaján, J; Skowronek, P; Twardowski, T | 1 |
| Barros, N; Cardien, LC; D'Almeida, V; Ferreira, SR; Garofolo, L; Miranda, F | 1 |
| Pofelski, J; Roblin, X; Zarski, JP | 1 |
| Chae, EH; Chang, N; Kim, JM; Kim, SJ; Lee, H; Lee, I | 1 |
| Albeck, M; Carmely, A; Dikshtein, Y; Frei, G; Levy, E; Ofir, A; Okun, E; Saida, H; Sela, BA; Sredni, B; Varshavsky, L | 1 |
| Akoglu, B; Bolouri, H; Caspary, WF; Faust, D; Jaffari, A; Kutschera, E; Schrott, M | 1 |
| Moshal, KS; Sen, U; Singh, M; Tyagi, N; Tyagi, SC | 1 |
| Berthier, S; Bonnotte, B; Falvo, N; Ghiringhelli, F; Lorcerie, B | 1 |
| Arsenault, L; Buel, J; Buell, J; Folstein, M; Liu, T; Peter, I; Qiu, WW; Scott, T | 1 |
| Delabar, JM; Fulchiron, R; Hamelet, J; Janel, N; Maurin, N | 1 |
| Budavari, AI; Hartsell, Z | 1 |
| Caprini, JA; Eldibany, MM | 1 |
| Kothekar, MA | 1 |
| Belcastro, V; Caccamo, D; Gaetano, G; Ientile, R; Italiano, D; Oteri, G; Pisani, F; Pisani, LR; Striano, P; Striano, S | 1 |
| Hauner, H | 1 |
| Biagini, MR; Bongini, E; Capanni, M; Galli, A; Milani, S; Surrenti, C; Tozzi, A | 1 |
| Ancora, MA; Carluccio, M; Carluccio, MA; De Caterina, R; Distante, A; Massaro, M; Scoditti, E; Storelli, C | 1 |
| Alonso, E; Arauz, A; Cantú, C; Fernández, Mde L; García, I; Hoyos, L; Jara, A; Martínez, L | 1 |
| Cupini, LM; Stipa, E | 1 |
| Angeli, A; Borrione, P; Massazza, G; Paccotti, P; Pigozzi, F; Schonhuber, H; Viberti, G | 1 |
| Papadimitriou, DK; Pitoulias, GA; Tachtsi, MD; Tsiaousis, PZ | 1 |
| Marcus, J; Menon, V; Sarnak, MJ | 1 |
| Hanchaipiboolkul, S; Moleerergpoom, W; Sura, T; Tantirittisak, T | 1 |
| Agnati, LF; Andreoli, N; Astancolle, S; Carone, C; Davalli, P; Filaferro, M; Fuxe, K; Genedani, S; Leo, G | 1 |
| Huang, RF; Kuo, CS; Liao, SL; Wong, KC; Wu, MY; Yang, LK | 1 |
| Faghihi, H; Farahvash, MS; Karkhaneh, R; Maghsoudipour, M; Moghimi, S; Najmi, Z | 1 |
| Ben Ghorbel, I; El Matri, L; Fki, M; Ghannouchi, M; Hamzaoui, K; Houman, MH; Jeddi, A; Khanfir, M; Lamloum, M; Miled, M; Naffati, H | 1 |
| Chan, A; Chen, S; Rogers, EJ | 1 |
| Wierzbicki, AS | 1 |
| Jiang, SL; Ni, M; Zhang, XH; Zhang, Y | 1 |
| Alina, AR; Bondar', IA; Pechkovskiĭ, EV; Pikalov, IV | 1 |
| Albers, U; Alder, M; Barrios, L; Castillo, MJ; Gonzalez-Gross, M; Pietrzik, K; Sola, R | 1 |
| Chen, SS; Chen, TH; Chen, WH; Huang, CW; Lai, SL; Lin, HS; Liu, JS; Tseng, YL | 1 |
| Cohn, J; Jiang, H; Maclean, KN; Mikael, LG; Rozen, R; Schwahn, BC; Wang, XL; Wu, Q | 1 |
| Bugan, B; Celik, T; Isik, E; Iyisoy, A; Yuksel, UC | 1 |
| Arai, H; Egashira, T; Hattori, H; Horibe, H; Ishikawa, Y; Itakura, H; Kita, T; Mabuchi, H; Matsuzawa, Y; Nakaya, N; Oikawa, S; Ouchi, Y; Saito, Y; Sasaki, J; Teramoto, T; Yamada, N; Yamamoto, A | 1 |
| Chandra, R; Rai, SK; Sharma, M; Tiwari, M | 1 |
| Blum, A; Blum, N; Eizenberg, MM; Hijazi, I | 1 |
| Klein, A; Linnebank, M; Moskau, S; Semmler, A | 1 |
| Herrmann, W; Lorenzl, S; Obeid, R | 1 |
| Ageno, W; Dentali, F; Ghirarduzzi, A; Pesavento, R; Prandoni, P; Romualdi, E | 1 |
| Cao, J; Jiang, Y; Li, G; Sun, T; Wang, S; Xiong, J | 1 |
| Papatheodorou, L; Weiss, N | 1 |
| Handy, DE; Loscalzo, J; Lubos, E | 1 |
| Donmez, L; Herrmann, M; Ozdem, S; Sadan, G; Samanci, S; Tasatargil, A; Yildiz, A | 1 |
| Kumar, M; Moshal, KS; Rodriguez, WE; Sen, U; Tyagi, N; Tyagi, SC | 1 |
| Bednarek-Tupikowska, G; Bidzińska, B; Bohdanowicz-Pawlak, A; Filus, A; Kuliczkowska, J; Milewicz, A; Szymczak, J; Tupikowski, K | 1 |
| Aksungar, FB; Ayalp, S; Boru, UT; Karsidag, S; Sahin, S; Topkaya, AE; Yildiz, Z | 1 |
| D'Almeida, V; de Carvalho, JF; de Souza, AW; Noguti, MA; Sato, EI; Silva, NP | 1 |
| Christopher, R; Nagaraja, D; Shankar, SK | 1 |
| Bleich, S; Frieling, H; Hillemacher, T; Muschler, MA | 1 |
| Armstrong, VW; Bachmann, CG; Guth, N; Happe, S; Helmschmied, K; Paulus, W | 1 |
| Garcia, VD; Keitel, E; Piovesan, F; Pozza, R; Saitovitch, D; Santos, AF; Sarturi, PS; Tognon, A; Veronese, FJ | 1 |
| Belcastro, V; Caccamo, D; Calabresi, P; Currò, M; Di Iorio, W; Gorgone, G; Ientile, R; Menichetti, C; Parisi, G; Parnetti, L; Pisani, F; Rossi, A | 1 |
| Hasegawa, H; Hashimoto, T; Shinohara, Y | 1 |
| Majluf-Cruz, A; Montano-Loza, A; Uscanga, L; Vargas-Vorackova, F; Zapata-Colindres, JC; Zepeda-Gómez, S | 1 |
| Elmore, CL; Matthews, RG | 1 |
| Dai, J; Wang, X | 1 |
| Chen, H; Li, J; Li, L; Liu, X; Luo, F; Wu, W | 1 |
| Josse, RG; Lonn, E; Ray, JG; Sawka, AM; Yi, Q | 1 |
| Aït-Yahya-Graison, E; Badel-Chagnon, A; Camproux, AC; Delabar, JM; Demuth, K; Hamelet, J; Janel, N; Matulewicz, E; Noll, C; Paul, JL | 1 |
| Amini, AL; Amiri, M; Jafari, SM; Nabipour, I; Pazoki, R; Riazi, A; Sanjdideh, Z; Shafeiae, E; Vahdat, K | 1 |
| Au-Yeung, KK; Hwang, SY; O, K; Siow, YL; Woo, CW; Zhu, TY | 1 |
| Burcombe, RJ; Cladd, H; Cooper, P; Gatt, A; Makris, A; Makris, M; Smith, JM; Thompson, D | 1 |
| Asfar, S; Safar, HA | 1 |
| Herrmann, M; Herrmann, W; Sen, U; Tyagi, SC | 1 |
| Luo, Y; Wang, J; Yang, X; Zhou, X | 1 |
| Barschak, AG; Matté, C; Netto, CA; Scherer, EB; Stefanello, FM; Vargas, CR; Wyse, AT | 1 |
| O, K; Siow, YL; Woo, CWH | 1 |
| Barsacchi, R; Barsanti, L; Battaglia, D; Kusmic, C; Palombo, C; Paolicchi, A; Parodi, O; Taddei, MC; Vesentini, N | 1 |
| das Graças Carvalho, M; de Castro Santos, ME; Dusse, LM; Fernandes, AP; Lima, LM; Mota, AP; Ribeiro, DD; Sabino, A; Sousa, MO | 1 |
| Abalain, JH; Lacut, K; Le Gal, G; Mottier, D; Oger, E | 1 |
| Baines, M; Davison, A; Fraser, WD; Higgins, G; Kredan, MB; Ranganath, LR; West, C | 1 |
| Barraud, H; Bronowicki, JP; Guéant, JL; Lalonde, R; Ravey, J; Strazielle, C | 1 |
| Edirimanne, VE; O, K; Pierce, GN; Siow, YL; Woo, CW; Xie, JY | 1 |
| Ilhan, N; Kaman, D; Kucuksu, M; Ozbay, Y | 1 |
| Alam, MA; Chauhan, SS; Husain, SA; Kabra, M; Narang, R; Vasisht, S | 1 |
| Aguglia, U; Battaglia, L; Condino, F; de Marco, V; Luise, F; Morabito, F; Morabito, P; Piromalli, A; Quattrone, A; Russo, C; Trapani Lombardo, V; Vinci, A | 1 |
| Abbud-Filho, M; Biselli, PM; Cardoso, MA; Eberlin, MN; Ferreira-Baptista, MA; Galbiatti, AL; Goloni-Bertollo, EM; Goto, MT; Haddad, R; Pavarino-Bertelli, EC; Sanches de Alvarenga, MP | 1 |
| Capasso, R; De Santo, NG; Ingrosso, D; Lombardi, C; Luciano, MG; Perna, AF; Pulzella, P; Satta, E | 1 |
| Schulz, RJ | 1 |
| Distrutti, E; Donini, A; Fiorucci, S; Mencarelli, A; Orlandi, S; Renga, B; Santucci, L; Shah, V | 1 |
| Lai, L; Liu, F; Liu, G; Wang, B; Wang, R; Yin, H; Yu, S; Zhang, J | 1 |
| Chen, T; Deaciuc, I; McClain, CJ; Song, Z; Zhou, Z | 1 |
| Kurul, S; Unalp, A; Yiş, U | 1 |
| Ayotunde, A; Hughes, WM; Kumar, M; Metreveli, N; Moshal, KS; Rodriguez, WE; Rosenberger, DS; Sen, U; Singh, M; Sithu, SD; Tyagi, N; Tyagi, SC; Vacek, TP; Zeldin, DC | 1 |
| Cigerim, N; Karabudak, E; Kiziltan, G | 1 |
| Jiang, C; Li, Y; Tang, C; Wang, N; Wang, X; Xu, G; Zhu, Y | 1 |
| Lamberti, P; Logroscino, G; Samarelli, V; Serlenga, L; Simone, IL; Tortelli, R; Zoccolella, S | 1 |
| Hillenbrand, A; Hillenbrand, R; Liewald, F; Zimmermann, J | 1 |
| De Angelis, S; Diana, L; Palleschi, S; Papa, V; Rossi, B; Severini, G; Splendiani, G | 1 |
| Bolca, O; Cakmak, N; Nurkalem, Z; Onturk, E; Sahin, S; Sayar, N; Tangurek, B; Yilmaz, H; Yilmaz, M | 1 |
| Medina, MA; Montañez, R; Rodríguez-Alonso, J; Rodríguez-Caso, L | 1 |
| Angeli, A; Borrione, P; Dovio, A; Fagnani, F; Parisi, A; Pigozzi, F; Rizzo, M; Salvo, RA; Spaccamiglio, A; Termine, A | 1 |
| Khoroshko, ND; Kulikov, SM; Levina, AA; Mamukova, IuI; Manakova, TE; Orel, EB; Rokhnianskaia, AA; Romanova, EA; Rudakova, VE; Semenova, EA; Sokolova, MA; Sudarikov, AB; Sukhanova, GA; Tsvetaeva, NV; Turkina, AG; Tutaeva, VV; Vasil'ev, SA | 1 |
| Alley, RA; Beyer, TD; Chen, EL; Prinz, RA | 1 |
| Akin, R; Demirkaya, E; Gokçay, E; Gul, D; Kul, M; Unay, B; Vurucu, S | 1 |
| Bodamer, OA; Födinger, M; Herle, M; Huemer, M; Möslinger, D; Mühl, A; Stöckler-Ipsiroglu, S; Ulmer, H; Weigmann, C | 1 |
| Carvajal, Z; Marchi, R; Weisel, JW | 1 |
| Abdella, NA; Al Humood, S; Al Shayeb, AR; Al Wazzan, H; El-Muzaini, H; Marouf, R; Mojiminiyi, OA; Qurtom, M; Samad, MA | 1 |
| Anan, F; Eshima, N; Fujiki, M; Kobayashi, H; Saikawa, T; Shimomura, T; Umeno, Y; Yoshimatsu, H | 1 |
| Boeger, RH; Deussen, A; Henle, T; Pexa, A; Schwedhelm, E | 1 |
| Manore, MM; Woolf, K | 1 |
| Asadi, N; Dehbashi, S; Kazerooni, T; Zolghadri, J | 1 |
| Benyamina, A; Debuire, B; Karila, L; Lemoine, A; Marill, C; Pham, P; Reffas, M; Reynaud, M; Saffroy, R | 1 |
| Beavers, DP; Beavers, KM; Bowden, RG; Gentile, M; Wilson, RL | 1 |
| de Jonge, R; Dunkelgrun, M; Feringa, HH; Goei, D; Hoeks, SE; Lindemans, J; Poldermans, D; Schouten, O; van Domburg, RT; van Gestel, YR; Vidakovic, R; Welten, GM | 1 |
| Cutler, MJ; Freeman, DJ; House, AA; Mainra, R; Spence, JD; Urquhart, BL | 1 |
| Austin, RC; DiBello, PM; Dickhout, J; Jacobsen, DW; Lhoták, S; Majors, AK; Shi, YY; Tedesco, V; Trigatti, B; Werstuck, GH; Zhou, J | 1 |
| Bambara, LM; Biasi, D; Caramaschi, P; Patuzzo, G; Tinazzi, I | 1 |
| Toohey, JI | 1 |
| Brehm, A; Brión, M; Carracedo, A; Freitas, AI; Guerra, G; Mendonça, I; Reis, RP | 1 |
| Barbaresi, M; Bracci, M; Copertaro, A; Santarelli, L | 1 |
| Frank, I; Metreveli, N; Moshal, KS; Tyagi, SC | 1 |
| Geisel, J; Hentschel, B; Herrmann, W; Kuntze, T; Rassoul, F; Richter, V | 1 |
| Ducros, V; Dufouil, C; Tzourio, C; Vidal, JS | 1 |
| Corrêa, FM; de Andrade, CR; de Oliveira, AM; Eberlin, MN; Haddad, R; Resstel, LB | 1 |
| Medina, MA | 1 |
| Antolini, L; Conti, E; DeFilippi, F; Facheris, M; Fenaroli, F; Ferrarese, C; Galimberti, G; Isella, V; Perlangeli, V; Piazza, F; Zini, M | 1 |
| Gupta, S; Hua, X; Kozich, V; Krijt, J; Kruger, WD; Wang, L | 1 |
| El Bouchti, I; Kuntz, JL; Sibilia, J; Sordet, C | 1 |
| Au, R; Beiser, AS; D'Agostino, RB; DeCarli, C; Jacques, PF; Rosenberg, IH; Selhub, J; Seshadri, S; Wolf, PA; Yoshita, M | 1 |
| Lentz, SR; Rodionov, RN | 1 |
| Bachnalkar, A; Christopher, R; Diwakar, L; Nagaraja, D; Ravindranath, V; Rudresh Kumar, KJ | 1 |
| Camporesi, EM; Karlnoski, RA; Luzardo, GE; Mangar, D; Williams, B | 1 |
| Bissé, E; Dierkes, J; Luley, C; Mayer, H; Nauck, M; Orth, M; Wieland, H | 1 |
| Bos, GM; Den Heijer, M; Gerrits, WB; Willems, HP | 1 |
| Franco, A; Haverstick, L; Malone, M; Rothkopf, MM; Usiskin, K | 1 |
| Bellet, E; Chassé, JF; Dupuy, E; Janbon, C; Molho-Sabatier, P; Quéré, I; Tobelem, G | 1 |
| Baker, RI; Eikelboom, JW | 1 |
| Han, Q; Hoffman, RM; Lenz, M; Miljkovic, D; Sun, X; Tan, X; Tan, Y; Tang, L; Xu, M | 1 |
| Boucher, BJ; Iles, RA; Mannan, N; Obeid, OA; Perry, G | 1 |
| Crombleholme, WR; Evans, RW; Majors, AK; Ness, RB; Ojimba, JI; Powers, RW; Roberts, JM | 1 |
| Ali, A; Lavie, CJ; Li, S; Lin, HC; Lohmann, TP; Malik, FS; Mehra, MR; Milani, RV; Murgo, JP | 1 |
| Ubbink, JB | 2 |
| de Bruijne, EL; Keulen-de Vos, GH; Ouwendijk, RJ | 1 |
| Moustapha, A; Robinson, K | 2 |
| Wilcken, DE | 1 |
| Danesh, J; Lewington, S | 1 |
| Graham, IM; Meleady, RA | 1 |
| Domagała, TB; Libura, M; Szczeklik, A; Undas, A | 1 |
| Clarke, R; Collins, R | 1 |
| Asmi, M; Busjahn, A; Joubran, R; Jouma, M; Luft, FC; Vergopoulos, A | 1 |
| Moneta, GL; Porter, JM; Schuff, RA; Sexton, GJ; Taylor, LM | 1 |
| Cameron, DP; Gibbs, H; Hickman, PE; Kesting, JB; Marczak, M; McWhinney, B; Purdie, D; Shaw, JT; Tate, JR | 1 |
| Ambrosch, A; Bosselmann, HP; Dierkes, J; Domröse, U; Luley, C; Neumann, KH | 1 |
| Chambers, JC; Jean-Marie, J; Kooner, JS; McGregor, A; Obeid, OA | 1 |
| de Meer, K; Donker, AJ; Janssen, MJ; Stehouwer, CD; van Guldener, C | 1 |
| Assanelli, D; Bersatti, F; Bollani, G; Cattaneo, M; Ferrari, M; Ferrari, R; Visioli, O; Zighetti, ML | 1 |
| Arheart, K; Dennis, VW; Gupta, A; Jacobsen, DW; Moustapha, A; Robinson, K; Schreiber, MJ | 1 |
| Bignell, MK; Bullemer, FE; Graham, KJ; Hanson, NQ; Rasmussen, R; Schwichtenberg, K; Tsai, MY; Vessey, J; Welge, BG; Yang, F | 1 |
| Banga, JD; Biesma, DH; Duran, M; Haas, FJ; Meuwissen, OJ; van der Griend, R | 1 |
| Hall, TN; Leahy, MF; Ramakrishnan, LL | 1 |
| Blom, HJ; den Heijer, M; Smeitink, JA; te Poele Pothoff, MT; van Beynum, IM | 1 |
| Carlberg, B; Dahlén, G; Hultdin, J; Kristensen, B; Malm, J; Nilsson, TK; Olsson, T | 1 |
| Födinger, M; Hörl, WH; Papagiannopoulos, M; Sunder-Plassmann, G; Vychytil, A; Wölfl, G | 1 |
| Aarsland, T; Grundt, H; Hetland, O; Mansoor, MA; Nilsen, DW; Woie, L | 1 |
| Bostom, AG; Selhub, J | 1 |
| Beilby, JP; Hung, J; McQuillan, BM; Nidorf, M; Thompson, PL | 1 |
| Blom, HJ; Bos, GM; den Heijer, M; Gerrits, WB; Rosendaal, FR; Willems, HP | 1 |
| Alders, D; de Jong, SC; Jakobs, C; Kostense, PJ; Pals, G; Rauwerda, JA; Stehouwer, CD; van den Berg, M | 1 |
| Cha, DR; Cho, WY; Huh, K; Kim, HK; Kwon, YJ; Lee, YK; Oh, KS; Pyo, HJ; Yoon, JW | 1 |
| Aarnoudse, JG; Lubbers, MF; van Doormaal, JJ | 1 |
| Bates, CJ; Berge, T; Drabløs, PA; Hervig, T; Hetland, O; Kristensen, O; Mansoor, MA; Osland, A; Pentieva, K; Rolfsen, S; Vefring, H | 1 |
| Abel, JG; Cook, RC; Frohlich, JJ; Gao, M; Ignaszewski, AP; Kingsbury, K; Parker, S; Tupper, JK | 1 |
| Andreotti, F; Burzotta, F; Manzoli, A; Maseri, A; Mazza, A; Robinson, K | 1 |
| Allen, JC; Bonham, JR; Moat, SJ; Powers, HJ; Tanner, MS | 1 |
| Bodis, M; Geisel, J; Herrmann, W; Quast, S; Schultze, H; Ullrich, M | 1 |
| Cordy, P; Freeman, D; Kortas, C; Spence, JD | 1 |
| Cable, GG | 1 |
| Beaulieu, AJ; Bostom, AG; Dworkin, L; Gohh, RY; Han, H; Jacques, PF; Liaugaudas, G; Rosenberg, IH; Selhub, J | 1 |
| Bots, ML; Breteler, MM; Hofman, A; Kalmijn, S; Launer, LJ; Lindemans, J | 1 |
| Boers, GH; de Jong, SC; Devillé, W; Jakobs, C; Pals, G; Rauwerda, JA; Stehouwer, CD; van den Berg, M | 1 |
| Bouter, LM; de Jong, SC; Geurts, TW; Rauwerda, JA; Stehouwer, CD; van den Berg, M | 1 |
| Laskin, CA; Ray, JG | 1 |
| Artuch, R; Campistol, J; Cardo, E; Colomé, C; Pineda, M; Vilaseca, MA | 1 |
| Faiman, C; Green, R; Hussein, WI; Jacobsen, DW | 1 |
| Eikelboom, JW; Genest, J; Hankey, G; Lonn, E; Yusuf, S | 1 |
| Harjai, KJ | 1 |
| Graham, I | 1 |
| Puddu, P | 1 |
| Solenthaler, M; Wuillemin, WA | 1 |
| Allen, RH; Cohen, JA; Estacio, R; Jeffers, BW; Schrier, RW; Stabler, SP | 1 |
| Allaman, M; Browning, RL; Haynes, WG; Kanani, PM; Knapp, HR; Sinkey, CA | 1 |
| Gravel, RA; Leclerc, D; Rosenblatt, DS; Wilson, A | 1 |
| Cheng, TO | 1 |
| Augier, T; Bescond, A; Chareyre, C; Charpiot, P; Garçon, D; Hornebeck, W | 1 |
| Alpert, MA | 1 |
| Oakley, GP | 1 |
| Perry, IJ | 1 |
| Burgess, ED; Hyndman, ME; Manns, BJ; Parsons, HG; Schaefer, JP; Scott-Douglas, NW | 1 |
| Panini, R; Pasini, MC; Salvioli, G; Scarpetta, G; Ventura, P | 1 |
| Doshi, SN; Goodfellow, J; Lewis, MJ; McDowell, IF | 1 |
| Donker, AJ; Lambert, J; Rauwerda, JA; Stehouwer, CD; Steyn, M; van den Berg, M | 1 |
| Keller, C; Pietrzik, K; Weiss, N | 1 |
| Ciuffetti, G; Locati, EH; Lombardini, R; Lupattelli, G; Mannarino, E; Rufini, S; Siepi, D | 1 |
| Pasceri, V; Willerson, JT | 1 |
| Altura, BM; Altura, BT; Li, W; Wang, J; Zheng, T | 1 |
| Grimble, GK | 1 |
| Celermajer, DS; Chook, P; Lolin, YI; Metreweli, C; Sanderson, JE; Woo, KS | 1 |
| Andreotti, F; Burzotta, F; Manzoli, A; Robinson, K | 1 |
| Beaulieu, AJ; Bostom, AG; Gohh, RY; Hakas, D; Han, H; Jacques, PF; Selhub, J | 1 |
| Blann, AD; Boisseau, M; Conri, C; Constans, J; Guérin, V; Parrot, F; Renard, M; Resplandy, F; Seigneur, M | 1 |
| Kircher, T; Sinzinger, H | 1 |
| Chao, CL; Chien, KL; Lee, YT | 1 |
| Ridker, PM | 1 |
| Dudman, NP | 1 |
| Tsai, MY | 1 |
| Auberger, K; Homberger, A; Junker, R; Koch, HG; Linnebank, M; Nabel, P; Nowak-Göttl, U; Schobess, R | 1 |
| Chao, CL; Kuo, TL; Lee, YT | 1 |
| Chambers, JC; Hackett, D; Hooper, J; Kooner, JS; Obeid, OA; Refsum, H; Thompson, SG; Turner, RM; Ueland, P | 1 |
| Park, SC; Yoo, JH | 1 |
| Bar-On, H; Ben-Yehuda, A; Friedlander, Y; Friedman, G; Kidron, M; Rosenberg, IH; Selhub, J | 1 |
| Genest, J | 1 |
| Jahn, B; Kirchgessner, M; Schwarz, FJ; Stangl, GI | 1 |
| Archbold, GP; Harmon, DL; Lennox, S; Linton, T; McMaster, D; McNulty, H; Rea, IM; Whitehead, AS; Woodside, JV; Young, IS | 1 |
| Cacoub, P; Foglietti, MJ; Godeau, P; Hamidou, S; Hausfater, P; Jacob, N; Piette, JC; Tazi, Z | 1 |
| Krumdieck, CL; Prince, CW | 1 |
| Arnadottir, M; Gudnason, V; Hultberg, B | 1 |
| Celermajer, DS; Chan, LT; Cheung, AS; Chook, P; Lolin, YI; Metreweli, C; Sanderson, JE; Sun, YY; Woo, KS | 1 |
| Brouwer, IA; Duran, M; Eskes, TK; Hautvast, JG; Steegers-Theunissen, RP; Thomas, CM; van Dusseldorp, M | 1 |
| Banga, JD; Biesma, DH; van der Griend, R | 3 |
| Cole, DE; Evrovski, J; Langman, LJ; Ray, JG; Yeo, E | 1 |
| Quéré, I | 1 |
| Andrés, A; Carillo, JL; Díaz-Rubio, P; Estenoz, J; Fernández-Miranda, C; Gómez, P; Morales, JM | 1 |
| Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE | 1 |
| Gejyo, F; Kimura, H; Miyazaki, R; Suzuki, S | 1 |
| Ellgass, A; Herrmann, W; Kiessig, ST; Molinari, E; Quast, S; Riegel, W; Wolter, K | 1 |
| Bagley, PJ; Choi, SW; Kim, YI; Mason, JB; Russell, RM; Seitz, HK; Selhub, J; Stickel, F | 1 |
| Dudman, NP; Fu, W; Perry, MA; Wang, XL; Young, K | 1 |
| Cerbone, AM; Coppola, A; D'Angelo, A; Fermo, I; Galli, L; Madonna, P; Mazzola, G; Pagano, A | 1 |
| Floth, A; Födinger, M; Sunder-Plassmann, G | 1 |
| Bouter, LM; Dekker, JM; Heine, RJ; Hoogeveen, EK; Jakobs, C; Kostense, PJ; Nijpels, G; Rauwerda, JA; Stehouwer, CD | 1 |
| Fridman, O | 1 |
| Bieglmayer, C; Buchmayer, H; Födinger, M; Heinz, G; Hörl, WH; Schindler, K; Sunder-Plassmann, G; Wilfing, A; Wölfl, G; Zauner, C | 1 |
| Mizock, BA | 1 |
| Chisholm, A; Mann, JI; Riddell, LJ; Williams, S | 1 |
| Vine, AK | 2 |
| Bode-Böger, SM; Böger, RH; Heistad, DD; Lentz, SR; Sydow, K | 1 |
| Blom, HJ; Eskes, TK; Monnens, LA; Nováková, I; van der Molen, EF; Verbruggen, B | 1 |
| Fiedor, P; Polakowska, MJ; Socha, MW; Socha-Urbanek, K | 1 |
| Perry, DJ | 1 |
| Bagley, P; Bostom, AG; Christopher, K; Dworkin, L; Jacques, PF; Massy, ZA; Selhub, J; Shemin, D; Spiegel, P; Zanabli, A | 1 |
| Biasioli, S; Schiavon, R | 1 |
| Lynn, K; McGregor, D; Shand, B | 1 |
| Hashimoto, S; Midorikawa, S; Sanada, H; Watanabe, T | 1 |
| Stehouwer, DA | 1 |
| Brattström, L | 1 |
| Bernhard, W; Fuchs, D; Ledochowski, M | 1 |
| Allen, RH; Blom, HJ; Brattström, L; Finkelstein, JD; Jacobsen, DW; Lentz, SR; Malinow, MR; Mudd, SH; Refsum, H; Rosenberg, IH; Selhub, J; Stabler, SP; Ueland, PM; Wilcken, B; Wilcken, DE | 1 |
| Abbate, R; Brunelli, T; Capanni, M; Federici, G; Fedi, S; Gensini, GF; Gori, AM; Marcucci, R; Pastore, A; Pepe, G; Prisco, D; Simonetti, I | 1 |
| Duarte, N; Trudinger, BJ; Wang, J; Wang, XL; Wilcken, DE | 1 |
| Law, MR; Wald, NJ | 1 |
| Molloy, AM; Scott, JM; Weir, DG | 1 |
| Coppola, A; Di Minno, G; Mancini, FP; Margaglione, M | 1 |
| Bar-Meir, E; George, J; Shoenfeld, Y | 1 |
| Doolman, R; Sela, BA | 1 |
| Bonnardeaux, A; Busque, L; Geadah, D; Leblanc, M; Lebrun, M; Ouimet, D; Tremblay, R | 1 |
| Almog, Y; Goldstein, M; Loewenstein, A; Man, O; Pianka, P; Sela, BA | 1 |
| Brattström, L; Wilcken, DE | 1 |
| Beresford, SA; Refsum, H; Ueland, PM; Vollset, SE | 1 |
| Scott, JM | 1 |
| Audelin, MC; Genest, J; Lonn, E | 1 |
| Booth, GL; Wang, EE | 1 |
| Hamada, C; Kitaoka, M; Kurihara, H; Kuwaki, T; Morita, H; Nagai, R; Suzuki, S; Yazaki, Y | 1 |
| Makris, M | 1 |
| McKinley, MC | 1 |
| Banga, JD; Biesma, DH; Duran, M; Faber, JA; Haas, FJ; Meuwissen, OJ; van der Griend, R | 1 |
| Morrow, LE | 1 |
| Beloqui, O; Cienfuegos, JA; Herrero, JI; Pardo, F; Prieto, J; Quiroga, J; Sangro, B | 1 |
| Robinson, K; Seshadri, N | 1 |
| Dayal, S; Erger, RA; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR | 1 |
| Amores-Sánchez, MI; Medina, MA | 1 |
| Smulders, YM | 1 |
| Dalton, M; Gadson, P; Limpach, A; Miles, R | 1 |
| Blom, HJ | 1 |
| Cerbone, AM; Coppola, A; Davi, G; De Stefano, V; Di Minno, G; Mancini, FP | 1 |
| Rozen, R | 1 |
| Refsum, H; Schneede, J; Ueland, PM | 1 |
| Bos, GM; den Heijer, M; Willems, HP | 1 |
| Robinson, K; van Guldener, C | 1 |
| Armitage, J; Clarke, R | 1 |
| Boers, GH; Naughten, ER; Wilcken, B; Wilcken, DE; Yap, S | 1 |
| Cornwell, PE; Lowenthal, EA; Mayo, MS; Thornley-Brown, D | 1 |
| Graefe, U; Henning, BF; Tepel, M; Zidek, W | 1 |
| Diaz-Arrastia, R | 1 |
| Bleich, S; Degner, D; Javaheripour, K; Kornhuber, J; Kurth, C; Quintela-Schneider, M; Rüther, E; Spilker, K; Wiltfang, J | 1 |
| Bek, T; Hansen, L; Ingerslev, J; Kristensen, HL | 1 |
| Gao, W; Jiang, N; Zhu, G | 1 |
| Cheong, HI; Cho, BK; Lee, BH; Shin, YS; Wang, KC | 1 |
| Födinger, M; Sunder-Plassmann, G; Winkelmayer, WC | 1 |
| Bang, BK; Bostom, AG; Dwyer, JT; Han, H; Jacques, PF; Kim, YS; Park, JH; Selhub, J | 1 |
| Ayala, D; Bremner, WF; Foley, S; Garbincius, J; Hermida, RC; Holmes, EW; Johnson, M; Kanabrocki, EL; Nemchausky, BA; Ryan, MD; Scheving, LE; Shirazi, P; Third, JL | 1 |
| Chao, TH; Chen, JH; Chen, TY; Li, YH; Lin, LJ; Tsai, LM; Tsai, WC | 1 |
| Woodside, JV; Young, IS | 1 |
| Clarke, R; Devlin, AM; Fernando, S; Halsted, CH; Ling, EH; Peerson, JM; Smith, AD | 1 |
| González, S; López-Quesada, EL; Vilaseca, MA | 1 |
| Kirchgessner, M; Roth-Maier, DA; Stangl, GI | 1 |
| Bowman, BA; Gunter, EW; Jacques, PF; Johnson, CL; Morris, MS; Rosenberg, IH; Selhub, J; Wright, JD | 1 |
| Bonham, JR; Moat, SJ; Powers, HJ | 1 |
| Delport, R | 1 |
| Caldarera, M; Cucinotta, D; Dalmonte, E; Forti, P; Grossi, G; Macini, P; Maioli, F; Ravaglia, G; Zanardi, V | 1 |
| Akita, T; Duan, J; Ikeda, H; Imaizumi, T; Murohara, T; Sasaki, K; Shimada, T; Shintani, S | 1 |
| Choi, KH; Han, DS; Hwang, JH; Kim, SI; Kim, YS; Lee, HY; Moon, JI; Paeng, KJ; Park, KI; Song, HY; Yoo, TH | 1 |
| Devaraj, S; Jialal, I | 1 |
| De Souza , C; Fonseca, V; Keebler, ME | 1 |
| Buysschaert, M; Dramais, AS; Hermans, MP; Wallemacq, PE | 1 |
| Bostom, AG; Dworkin, L; Hsu, N; Jacques, PF; Selhub, J; Shemin, D; Yango, A | 1 |
| Kurihara, H; Kurihara, Y; Morita, H; Nagai, R; Oh-Hashi, Y; Saito, Y; Shindo, T; Yazaki, Y; Yoshida, S | 1 |
| Dijkhuisen, R; Greaves, M; Meiklejohn, DJ; Vickers, MA | 1 |
| Okatani, Y; Reiter, RJ; Wakatsuki, A | 1 |
| Balcells, S; Ferrer, I; Garcia-Giralt, N; Grinberg, D; Mainou, C; Meco, JF; Ordovás, JM; Palá, M; Pintó, X; Vilaseca, MA | 1 |
| Castaldo, P; De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF | 1 |
| Stam, F; Stehouwer, CD; van Guldener, C | 1 |
| Ceballos, I; Chadefaux-Vekemens, B; Descamps-Latscha, B; Drüeke, TB; Jungers, P; Massy, ZA; Nguyen-Khoa, T | 1 |
| Födinger, M; Hörl, WH; Sunder-Plassmann, G; Wagner, OF | 1 |
| Bieglmayer, C; Födiger, M; Hörl, WH; Ignatescu, MC; Kletzmayr, J; Sunder-Plassmann, G | 1 |
| Busch, M; Fleck, C; Müller, A; Sperschneider, H; Stein, G | 1 |
| Bode-Böger, SM; Böger, RH; Haynes, WG; Knapp, HR; Lentz, SR | 1 |
| Barbé, F; Boisson, F; Chango, A; Christidès, JP; Galan, P; Guilland, JC; Hercberg, S; Nicolas, JP; Perrin, MO; Pfister, M; Potier De Courcy, G; Rabhi, K | 1 |
| Sandrick, K | 1 |
| Abrams, J; Chai, AU | 1 |
| Hsu, YC; Huang, RF; Lin, HL; Yang, FL | 1 |
| Anderstam, B; Bárány, P; Bergström, J; Filho, JC; Lindholm, B; Suliman, ME | 1 |
| Böger, RH; Sydow, K | 1 |
| Bostom, AG; Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J | 1 |
| Larrabure, G; Rene Malinow, M; Sanchez, SE; Ware-Jauregui, S; Williams, MA; Zhang, C | 1 |
| Alfie, J; Galarza, C; Kordich, L; Murúa, A; Quintana, I | 1 |
| Burgess, E; Hyndman, E; Manns, B; Parsons, H; Schaefer, J; Scott-Douglas, N; Snyder, F | 1 |
| Bald, E; Chwatko, G; Czupryniak, L; Drzewoski, J | 1 |
| Auer, J; Berent, R; Eber, B; Lassnig, E; Weber, T | 1 |
| Akyürek, O; Dinçer, I; Erol, C; Ertas, F; Gülec, S; Kiliçkap, M; Kumbasar, SD; Laleli, Y; Oral, D; Sipahi, E | 1 |
| Halsted, CH | 1 |
| Arning, E; Bottiglieri, T; Cardaioli, G; Caso, V; Gallai, V; Paciaroni, M; Parnetti, L | 1 |
| Haas, A; Stanger, O; Weger, M | 1 |
| Accinni, R; Bartesaghi, S; Campolo, J; Cursano, CF; De Leo, G; Galluzzo, C; Parodi, O; Vegezzi, PG | 1 |
| Hajjar, KA | 1 |
| Dilaveraki, E; Emmanouel, D; Ganotakis, E; Gravanis, A; Kouroumalis, EA; Koutroubakis, IE; Mouzas, IA; Vardas, E; Vlachonikolis, IG; Vrentzos, G | 1 |
| Daniel, J; Gradman, WS; Haji-Aghaii, M; Miller, B | 1 |
| Hoffer, LJ; Kaplan, LN; Mamer, OA | 1 |
| Apsner, R; Bieglmayer, C; Buchmayer, H; Födinger, M; Hagen, W; Hauser, AC; Hörl, WH; Ignatescu, M; Köller, E; Papagiannopoulos, M; Rehak, PH; Sunder-Plassmann, G | 1 |
| McNulty, H; McPartlin, J; Scott, JM; Strain, JJ; Ward, M; Weir, DG | 1 |
| Artuch, R; Cardo, E; Colomé, C; Farré, C; Monrós, E; Pineda, M; Valls, C; Vilaseca, MA | 1 |
| Billett, HH; Estrada, DA | 1 |
| Aguirre Errasti, C; Egurbide Arberas, MV | 1 |
| Bosselmann, KP; Dierkes, J; Domröse, U; Luley, C; Neumann, KH | 1 |
| Bogels, M; Niessen, HW; Rauwerda, JA; Stehouwer, CD; van Hinsbergh, VW; Vermeulen, EG | 1 |
| Bennett, M | 1 |
| Brzósko, S; Hryszko, T; Małyszko, J; Myśliwiec, M | 1 |
| Bamonti, F; Belardinelli, R; Bortone, L; Cavalca, V; Cighetti, G; De Franceschi, M; Guazzi, MD; Loaldi, A; Novembrino, C | 1 |
| Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J | 1 |
| de Meer, K; Stam, F; van Guldener, C | 1 |
| Bamonti-Catena, F; Colucci, P; De Franceschi, M; De Vecchi, AF; Finazzi, S; Lando, G; Maiolo, AT; Marocchi, A; Novembrino, C; Patrosso, C; Taioli, E | 1 |
| Bleich, S; Degner, D; Kornhuber, J; Kurth, C; Paulus, W; Sperling, W; Wegerer, V | 1 |
| Bamonti-Catena, F; Carrabba, M; Cavalca, V; Cighetti, G; Cortelezzi, A; Fracchiolla, NS; Lambertenghi Deliliers, G; Maiolo, AT; Motta, M | 1 |
| Bostom, AG; Jacques, PF; Liaugaudas, G; Rosenberg, IH; Selhub, J | 1 |
| Andersson, A; Ankerst, J; Hultberg, B; Larsson, K; Lindgren, A | 1 |
| Blache, D; Durand, P; Loreau, N; Lussier-Cacan, S; Prost, M | 1 |
| Dijck-Brouwer, DA; Fokkema, MR; Muskiet, FA; van Doormaal, JJ; Weijer, JM | 1 |
| Ron, D | 1 |
| Austin, RC; Dayal, S; Hossain, GS; Krisans, SK; Lentz, SR; Maeda, N; Malinow, MR; Shi, YY; Sood, SK; Werstuck, GH; Zhou, J | 1 |
| Kes, P | 1 |
| Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Robson, RA | 1 |
| Castaldo, P; Cimmino, A; De Santo, NG; di Carlo, E; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Bostom, AG; Chen, Z; Curtis Ellison, R; Eckfeldt, JH; Jacques, PF; Rozen, R; Selhub, J; Weisberg, IS | 1 |
| Chang, CJ; Chiang, CW; Hsu, LA; Hsu, TS; Ko, YL; Kuo, CT; Lee, YS; Sun, CF | 1 |
| Boers, GH | 1 |
| Arning, E; Bottiglieri, T; Dayal, S; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR; Sigmund, CD | 1 |
| Cieślik, G; Idzior-Waluś, B | 1 |
| Armani, U; Bertolini, S; Cerone, R; Minniti, G; Piana, A; Susco, G | 1 |
| Desai, A; Lankford, HA; Warren, JS | 1 |
| Lambert, LA; Sarkar, PK | 1 |
| Blanche, P; Jouve, P; Si-Larbi, AG | 1 |
| Bostom, AG; Jacques, PF; Rosenberg, IH; Selhub, J; Wilson, PW | 1 |
| Puzyrev, VP; Spiridonova, MG; Stepanov, VA | 1 |
| Ching, JY; Choi, PC; Leung, WK; Ma, PK; Ng, AC; Poon, P; Sung, JJ; Woo, KS | 1 |
| Deleu, D | 1 |
| Aksu, K; Bayindir, O; Doğanavşargil, E; Gümüşdiş, G; Keser, G; Kitapçioğlu, G; Oksel, F; Ozmen, D; Turgan, N | 1 |
| Bailey, R; Hanson, NQ; Hunninghake, DB; Rao, G; Tsai, MY | 1 |
| Lavie, L; Levy, Y; Yeromenko, Y | 1 |
| Alfthan, G; Aromaa, A; Heliövaara, M; Knekt, P; Marniemi, J; Reunanen, A; Rissanen, H | 1 |
| Belletti, S; Costantini, A; Crippa, M; Lorenzi, G | 1 |
| Hanratty, CG; Johnston, DG; McAuley, DF; McGrath, LT; Young, IS | 1 |
| Blom, HJ; de Bree , A; Kromhout, D; Verschuren, WM | 1 |
| Amores-Sánchez, MI; Medina, M; Urdiales, JL | 1 |
| Artner-Dworzak, E; Fuchs, D; Leblhuber, F; Reibnegger, G; Vrecko, K; Walli, J; Widner, B | 1 |
| Choi, JR; Kim, HK; Kim, JH; Shin, JS; Song, JW; Song, KS | 1 |
| Bang, BK; Bostom, AG; Chang, YK; Dwyer, JT; Han, H; Houser, RF; Jacques, PF; Jung, KA; Kim, S; Kim, YS; Park, JH; Selhub, J | 1 |
| Bamforth, F; Dias, VC; Fedorak, RN; Romagnuolo, J; Teltscher, M | 1 |
| Gadkari, M; Guttormsen, AB; Joglekar, A; Orning, L; Refsum, H; Sayyad, MG; Schneede, J; Ueland, PM; Ulvik, A; Vollset, SE; Yajnik, CS | 1 |
| Armani, U; Cerone, R; Lorini, R; Minniti, G; Piana, A | 1 |
| Barbaux, S; Evans, A; Gaughan, DJ; Kluijtmans, LA; McMaster, D; Whitehead, AS; Yarnell, JW; Young, IS | 1 |
| Gromeier, S; Herrmann, W; Julius, U; Pietzsch, J; Schorr, H | 1 |
| Cohen, JA; Estascio, R; Jeffers, BW; Schrier, RW; Stabler, S | 1 |
| Debreceni, L | 1 |
| Barbado Hernández, FJ; Gómez Cerezo, JF; Ríos Blanco, JJ; Suárez García, I; Vázquez Rodríguez, JJ | 1 |
| Ghods, AJ; Ghorbani, G; Savaj, S | 1 |
| Abbate, R; Brunelli, T; Fedi, S; Giusti, B; Marcucci, R; Pepe, G; Prisco, D | 1 |
| Lee, WJ; Sheu, WH; Wan, CJ; Wang, CW; Wu, HS | 1 |
| Baethmann, M; Blom, H; Göhlich-Ratmann, G; Hoffmann, GF; Kleinlein, B; Seiffert, P; Voit, T; Wendel, U | 1 |
| Erdei, F; Katona, A; Kondacs, A; Márk, L; Márki-Zay, J; Nagy, E | 1 |
| Haraki, T; Hirai, J; Inazu, A; Kajinami, K; Kawashiri, M; Kitoh, C; Koizumi, J; Mabuchi, H; Shimada, T; Takegoshi, T; Wakasugi, T | 1 |
| Chen, J; Cheng, L; Li, Y; Zhang, I | 1 |
| Austin, RC; Bentzon, J; Danielsen, CC; Falk, E; Møller, J; Ravn, HB; Zhou, J | 1 |
| Casorelli, I; Chiusolo, P; Danese, S; De Stefano, V; Gasbarrini, A; Gasbarrini, G; Giardina, B; Leone, G; Papa, A; Persichilli, S; Zappacosta, B | 1 |
| Nakanishi, T; Takamitsu, Y | 1 |
| Ward, M | 1 |
| Artner-Dworzak, E; Fuchs, D; Jaeger, M; Leblhuber, F; Widner, B; Wirleitner, B | 1 |
| Naurath, HJ | 1 |
| Bodis, M; Geisel, J; Herrmann, W; Hübner, U; Knapp, JP; Schorr, H; Zimbelmann, I | 1 |
| Konetschny, R; Renner, W; Stanger, O; Weger, M | 1 |
| Bárány, P; Bergström, J; Lindholm, B; Suliman, ME | 1 |
| Nelen, WL | 1 |
| Gao, W; Jiang, N; Meng, Z; Tang, J | 1 |
| Apeland, T; Mansoor, MA; Strandjord, RE | 1 |
| Cortese, C; Motti, C | 1 |
| Alimollah, A; Gao, SZ; Giannetti, N; Herity, NA; Hunt, SA; Schroeder, JS; Valantine, HA; Yeung, AC | 1 |
| Cole, DE; Daly, PA; Evrovski, J; Miner, SE; Ross, HJ; Verma, A | 1 |
| Ashfield-Watt, PA; Doshi, SN; McDowell, IF; Moat, SJ | 1 |
| Krishna, TP; Lakshmi, AV; Maniprabha, C | 1 |
| Wattanapenpaiboon, N | 1 |
| Arias, R; Avila, MA; Berasain, C; Caballería, J; Corrales, FJ; García-Tevijano, ER; Martín-Duce, A; Mato, JM; Rodríguez, JA | 1 |
| Balint, RF; Cooke, JP; Her, JH; Kimoto, M; Stühlinger, MC; Tsao, PS | 1 |
| Chen, Z; Tang, J; Xu, H | 1 |
| Födinger, M; Hagen, W; Hörl, WH; Sunder-Plass-Mann, G | 1 |
| Adachi, MT; Aso, T; Hashimoto, Y; Kawauchi, J; Kitajima, S; Oshiro, S; Zhang, C | 1 |
| Clarke, R; Stansbie, D | 1 |
| Panini, R; Salvioli, G; Scarpetta, G; Ventura, P; Verlato, C | 1 |
| Bjørke Monsen, AL; Ueland, PM | 1 |
| Artuch, R; Colomé, C; Fortuny, C; Muñoz-Almagro, C; Sierra, C; Valls, C; Vilaseca, MA; Vilches, MA | 1 |
| Chetrit, A; Dardik, R; Davidson, J; Eskaraev, R; Inbal, A; Ravid, B; Rosenberg, N; Sela, BA; Seligsohn, U; Streifler, JY; Zivelin, A | 1 |
| Rauwerda, JA; Stehouwer, CD; Steyn, M; Twisk, JW; van Dijk, RA | 1 |
| Bacchi-Reggiani, L; Branzi, A; Falchetti, E; Grigioni, F; Magelli, C; Magnani, G; Mantovani, V; Potena, L; Sassi, S; Sorbello, S; Viggiani, M | 1 |
| Haneda, T; Ishida, H; Kikuchi, K; Morimoto, K; Okamoto, K | 1 |
| Gillespie, JI; Hansrani, M; Stansby, G | 1 |
| Camps, J; Fernández-Ballart, J; Ferré, N; Gómez, F; Joven, J; Murphy, MM; Simó, JM | 1 |
| Eberli, FR; Flammer, Y; Hess, OM; Lange, H; Meier, B; Pin, R; Roffi, M; Schnyder, G; Turi, ZG | 1 |
| Abu-Lebdeh, HS; Flemming, KD; Nguyen, TT; O'Fallon, WM; Parisi, JE; Petty, GW; Sicks, JD; Wiebers, DO | 1 |
| Carlino, P; De Sole, P; Giardina, B; Martorana, GE; Minucci, A; Mordente, A; Persichilli, S; Zappacosta, B | 1 |
| Acevedo, M; Simpfendorfer, C; Tagle, R | 1 |
| Cerbone, AM; Cirillo, F; Coppola, A; de Stefano, V; Di Minno, G; Madonna, P; Orefice, G | 1 |
| Bierl, C; Cap, A; Heydrick, S; Loscalzo, J; Weiss, N; Zhang, YY | 1 |
| Butler, R; Morris, AD; Struthers, AD | 1 |
| Kurabayashi, M; Morita, H; Nagai, R; Saito, Y | 1 |
| Kubo, T; Matsubara, N; Miyakaw, S; Murakami, S; Saitoh, M; Shoji, M | 1 |
| Cadet, JL; Cutler, RG; Duan, W; Kruman, II; Ladenheim, B; Mattson, MP | 1 |
| Cattaneo, M; Chantarangkul, V; Mannucci, PM; Tripodi, A; Zighetti, ML | 1 |
| Cook, JW; Malinow, MR; Moneta, GL; Orloff, SL; Taylor, LM | 1 |
| Chang, SJ; Chou, HF; Huang, HB; Huang, PC; Hung, CJ; Li, YH; Lin, BF; Lu, SC | 1 |
| Barrera, G; Bunout, D; de la Maza, P; Gattás, V; Hirsch, S; Petermann, M | 1 |
| Brown, BA; Brozetti, JJ; Dick, JS; Hollifield, RD; Howard, RS; Marx, JL; Thach, AB; Ward, TP | 1 |
| Du, J; Li, J; Tang, C; Yao, X; Zhang, B; Zhang, Y | 1 |
| Falk, E; Møller, J; Zhou, J | 1 |
| Baydas, G; Canatan, H; Cikim, G; Gursu, MF | 1 |
| Beiser, A; D'Agostino, RB; Jacques, PF; Rosenberg, IH; Selhub, J; Seshadri, S; Wilson, PW; Wolf, PA | 1 |
| Cattaneo, M; Chantarangkul, V; Hoffman, RM; Tan, Y; Tripodi, A | 1 |
| Bellanuova, I; Benedetto, FA; Cataliotti, A; Fermo, I; Malatino, LS; Mallamaci, F; Soldarini, A; Tripepi, G; Zoccali, C | 1 |
| Buysschaert, M; Dramais, AS; Hermans, MP; Jamart, J; Wallemacq, P | 1 |
| Albertini, A; Archetti, S; Assanelli, D; Bani, P; Del Zotto, E; Gasparotti, R; Grassi, M; Magoni, M; Negrini, R; Padovani, A; Pezzini, A; Vignolo, LA | 1 |
| Warren, CJ | 1 |
| Cutler, RG; Evans, M; Haughey, N; Kruman, II; Kruman, Y; Kumaravel, TS; Lee, J; Lohani, A; Mattson, MP; Pedersen, WA | 1 |
| Dudman, NP; Fu, WY; Perry, MA; Wang, XL | 1 |
| Chen, YF; Li, N; Zou, AP | 1 |
| Abdelfatah, A; Alber, D; Chalopin, JM; Ducloux, D; Motte, G; Toubin, G | 1 |
| Desouza, C; Fonseca, V; Keebler, M; McNamara, DB | 1 |
| Hasty, R; Smolar, EN | 1 |
| Friedland, RP; Jacobsen, DW; Mizrahi, EH | 1 |
| Bettahar-Lebugle, K; Feugeas, O; Nisand, I; Ohl, J; Rongières, C; Wittemer, C | 1 |
| Avivi, I; Brenner, B; Hoffman, R; Lanir, N | 1 |
| Corrocher, R; Faccini, G; Friso, S; Girelli, D; Olivieri, O; Pignatti, PF; Pizzolo, F; Stranieri, C; Trabetti, E | 1 |
| Guo, J; Wang, X; Zeng, X; Zhang, Q | 1 |
| Cohen, B; Lima, J; Oppenheimer, SM; Sen, S | 1 |
| Meinitzer, A; Rehak, P; Rigler, B; Semmelrock, HJ; Stanger, OH; Tiran, A; Tiran, B | 1 |
| Battler, A; Birnbaum, Y; Magal, N; Mager, A; Shohat, M | 1 |
| Aukrust, P; Holm, T; Holven, KB; Nenseter, MS; Ose, L | 1 |
| Archetti, S; Assanelli, D; Boldini, A; Bonanome, A; Bonetti, P; Grassi, M; Pagnan, A; Pezzini, A; Ruggeri, G; Salvadori, G | 1 |
| Bieglmayer, C; Födinger, M; Hörl, WH; Ignatescu, MC; Kletzmayr, J; Sunder-Plassmann, G | 1 |
| Aimo, G; Canavese, C; Fenoglio, R; Massarenti, P; Mesiano, P; Messuerotti, A; Pauletto, D; Priolo, G | 1 |
| Funamizu, M; Hata, A; Hayashi, K; Hiejima, Y; Hirayama, H; Kawabata, M; Makita, Y; Nakamura, T; Saionji, K; Tago, K; Tajiri, M; Takano, H | 1 |
| Deutschmann, H; Haas, A; Renner, W; Schmut, O; Semmelrock, J; Stanger, O; Temmel, W; Weger, M | 1 |
| Heiss, G; Malinow, MR; Nieto, FJ; Schreiner, PJ; Stinson, VL; Szklo, M; Wu, KK | 1 |
| Delabar, U; Kloor, D; Luippold, G; Mühlbauer, B; Osswald, H | 1 |
| Bhuripanyo, K; Leowattana, W; Mahanonda, N; Pokum, S | 1 |
| Davies, G; Hudson, P; McCaddon, A; Regland, B | 1 |
| Ballarin, A; Bissoli, L; Bosello, O; Brocco, G; Caruso, B; Di Francesco, V; Mandragona, R; Trespidi, R; Zamboni, M | 1 |
| Lin, Z; Liu, J; Liu, S; Wang, W; Wu, Z; Zhang, Z; Zhao, D | 1 |
| Jackson, SH; Mangoni, AA | 1 |
| Rosenberg, IH | 1 |
| Bale, A; Balling, R; Christensen, B; Colmenares, C; Ernest, S; Gilfix, BM; Hosack, A; Mamer, OA; McGrath, J; Nadeau, JH; Rodier, M; Rosenblatt, DS; Sankoff, D | 1 |
| Filipovský, J; Hromádka, M; Mayer, O; Racek, J; Stehlík, P; Svobodová, V; Trefil, L; Zárybnická, M | 1 |
| Camera, L; Camera, MI; Galarza, CR; Janson, JJ; Kordich, L; Mayorga, LM; Morales, M; Murúa, A; Przygoda, PA; Quintana, I; Waisman, G | 1 |
| Afeltra, A; Amoroso, A; Del Porto, F; Francia, A; Galluzzo, S; Gandolfo, GM; Mitterhofer, AP; Vadacca, M | 1 |
| Algra, A; Banga, JD; de Jaegere, PP; Grobbee, DE; Pasterkamp, G; van der Graaf, Y | 1 |
| Ai, VH; Chow, WS; Lam, KS; O, K; Siow, YL; Tan, KC | 1 |
| Bucciarelli, P; Cafro, A; Mannucci, PM; Martinelli, I; Zighetti, ML | 1 |
| Abdel-Raheem, MM; Danielson, BD; Hebert, B; Koka, VK; Potti, A | 1 |
| Cumurcu, T; Doganay, S; Er, H; Evereklioglu, C; Ozerol, E; Sahin, K; Türköz, Y | 1 |
| Ducloux, D; Massy, ZA; Motte, G | 1 |
| Castañon, M; Diaz, ML; Freixas, E; Genoud, V; Kordich, L; Martino, D; Pereyra, H; Schiel, A; Schropp, J; Trimarchi, H | 1 |
| Jennings, I; Kitchen, S; Preston, FE; Smith, J; Woods, TA | 1 |
| Janssens, Y; van Wersch, JW; Zandvoort, JA | 1 |
| Deutschmann, H; Haas, A; Quehenberger, F; Renner, W; Schmut, O; Semmelrock, J; Stanger, O; Temmel, W; Weger, M | 1 |
| Andel, M; Janosíková, B; Kozich, V; Krupková-Meixnerová, L; Veselá, K; Vitová, A | 1 |
| Dvorsak, B; Ekart, R; Gorenjak, M; Hojs, R; Pecovnik-Balon, B | 1 |
| Elian, KM; Hoffer, LJ | 1 |
| Ahmad, FU; Devi, JR; Dwivedi, M; Guleria, R; Jain, K; Khanna, N; Luthra, K; Misra, A; Pandey, RM; Sharma, R; Vikram, NK | 1 |
| Asnani, S; Desouza, C; Fonseca, V; Homan, J; McNamara, DB; Murthy, SN | 1 |
| Costimba, I; Delaportas, N; Georgalidis, C; Kaliolia, I; Karaliotas, G; Katsarou, A; Klonou, E; Koulouridis, E; Krokida, A; Lachanas, A; Panagiotaki, E; Tzilianos, M | 1 |
| Deutschmann, H; Haas, A; Leitner, FJ; Renner, W; Schmut, O; Semmelrock, J; Stanger, O; Weger, M | 1 |
| Cook, JW; Malinow, MR; Orloff, SL; Yin, Q | 1 |
| Wu, JT; Wu, LL | 1 |
458 review(s) available for homocysteine and Hyperhomocysteinemia
| Article | Year |
|---|---|
The link between homocysteine, folic acid and vitamin B12 in chronic kidney disease.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Dialysis; Vitamin B 12 | 2021 |
Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
Topics: Aged; Bone Density; Dietary Supplements; Eating; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex | 2022 |
Hyperhomocysteinemia: Metabolic Role and Animal Studies with a Focus on Cognitive Performance and Decline-A Review.
Topics: Animals; Cognition; Cognitive Dysfunction; Homocysteine; Humans; Hyperhomocysteinemia; One-Carbon Group Transferases | 2021 |
Safety of Dietary Guanidinoacetic Acid: A Villain of a Good Guy?
Topics: Aged; Animals; Creatine; Dietary Supplements; Energy Metabolism; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Risk Assessment | 2021 |
Hyperhomocysteinemia and cardiovascular diseases.
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methionine; Risk Factors | 2022 |
Vitamin B-related Gene Polymorphisms and Cardiovascular Disease.
Topics: Aminohydrolases; Cardiovascular Diseases; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Neoplasm Proteins; Polymorphism, Genetic; Receptors, Cell Surface; Vitamin B 12; Vitamin B Complex | 2022 |
The Controversial Role of HCY and Vitamin B Deficiency in Cardiovascular Diseases.
Topics: Aged; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency | 2022 |
Homocysteine, Vitamins B6 and Folic Acid in Experimental Models of Myocardial Infarction and Heart Failure-How Strong Is That Link?
Topics: Animals; Folic Acid; Gasotransmitters; Heart Failure; Homocysteine; Hyperhomocysteinemia; Inflammation; Models, Theoretical; Myocardial Infarction; Vitamin B 6; Vitamins | 2022 |
Homocysteine and the Mortality of Critically Ill Patients: A Meta-Analysis.
Topics: Cohort Studies; Critical Illness; Homocysteine; Humans; Hyperhomocysteinemia; Intensive Care Units | 2022 |
Hyperhomocysteinemia in Cardiovascular Diseases: Revisiting Observational Studies and Clinical Trials.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2023 |
Epigenetic Regulation by microRNAs in Hyperhomocysteinemia-Accelerated Atherosclerosis.
Topics: Atherosclerosis; Biomarkers; Cholesterol; Epigenesis, Genetic; Homocysteine; Humans; Hyperhomocysteinemia; MicroRNAs | 2022 |
HOMOCYSTEINE AND CARDIOVASCULAR DISEASE - A CURRENT REVIEW.
Topics: Atherosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Reactive Oxygen Species | 2022 |
Association of hyperhomocysteinemia and chronic kidney disease in the general population: a systematic review and meta-analysis.
Topics: Cross-Sectional Studies; Databases, Factual; Homocysteine; Humans; Hyperhomocysteinemia; Renal Insufficiency, Chronic | 2023 |
Homocysteine as a predictor and prognostic marker of atherosclerotic cardiovascular disease: a systematic review and meta-analysis.
Topics: Aged; Atherosclerosis; Cardiovascular Diseases; Carotid Intima-Media Thickness; Child; Endothelial Cells; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prognosis; Risk Factors; Vitamin B 12 | 2023 |
Folate and retinal vascular diseases.
Topics: Diabetic Retinopathy; Endothelial Cells; Folic Acid; Glucose; Homocysteine; Humans; Hyperhomocysteinemia; Methionine | 2023 |
[Research progress on the role and mechanism of endothelial dysfunction in hyperhomocysteine-induced atherosclerosis].
Topics: Atherosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Risk Factors | 2023 |
Homocysteine, vitamin B12, and folate levels in patients with multiple sclerosis in Chinese population: A case-control study and meta-analysis.
Topics: Adult; Case-Control Studies; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multiple Sclerosis; Vitamin B 12 | 2019 |
Type 2 diabetes mellitus and cardiovascular risk; what the pharmacotherapy can change through the epigenetics.
Topics: Alarmins; Antihypertensive Agents; Cardiovascular Diseases; Chromatin; Diabetes Mellitus, Type 2; DNA Methylation; Endothelium, Vascular; Epigenesis, Genetic; Extracellular Traps; Gastrointestinal Microbiome; Histones; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Hypoglycemic Agents; Insulin; Metabolic Syndrome; Renin-Angiotensin System; Risk Factors; RNA, Untranslated | 2020 |
The association between homocysteine and ischemic stroke subtypes in Chinese: A meta-analysis.
Topics: Atherosclerosis; Brain Ischemia; China; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke | 2020 |
Environmental Pollution, Oxidative Stress and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis and Aging.
Topics: Aging; Animals; Atherosclerosis; Carcinogenesis; Electromagnetic Fields; Environmental Pollution; Fluorides; Glycine; Glyphosate; Homocysteine; Humans; Hyperhomocysteinemia; Mitochondria; Neoplasms; Oxidative Phosphorylation; Oxidative Stress; Vitamin B 12 | 2020 |
Gut microbiota and the periodontal disease: role of hyperhomocysteinemia.
Topics: Dysbiosis; Folic Acid; Gastrointestinal Microbiome; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Periodontitis; Probiotics | 2021 |
Elevated Homocysteine Levels Associated with Atrial Fibrillation and Recurrent Atrial Fibrillation.
Topics: Atrial Fibrillation; Case-Control Studies; Homocysteine; Humans; Hyperhomocysteinemia; Recurrence; Risk Assessment; Software | 2020 |
Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction.
Topics: Aging; Alzheimer Disease; Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Endoplasmic Reticulum Stress; Homocysteine; Humans; Hyperhomocysteinemia; Macular Degeneration; Oxidative Stress | 2020 |
Folic Acid Supplementation in Patients with Elevated Homocysteine Levels.
Topics: Animals; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2020 |
The Interaction between Arachidonic Acid Metabolism and Homocysteine.
Topics: Animals; Arachidonic Acid; Biomarkers; Cardiovascular Diseases; Heart Disease Risk Factors; Homocysteine; Humans; Hyperhomocysteinemia; Prognosis; Risk Assessment | 2021 |
Relationship between total plasma homocysteine and the risk of aneurysms - a meta-analysis.
Topics: Aneurysm; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Plasma | 2021 |
Hidradenitis Suppurativa and 1-Carbon Metabolism: Role of Gut Microbiome, Matrix Metalloproteinases, and Hyperhomocysteinemia.
Topics: Animals; Bacteria; Biomarkers; Diet, High-Fat; Dysbiosis; Gastrointestinal Microbiome; Hidradenitis Suppurativa; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinases; Risk Assessment; Risk Factors; Skin | 2020 |
Metabolic Consequences of Supplemented Methionine in a Clinical Context.
Topics: Animals; Body Fluid Compartments; Cardiovascular Diseases; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Proteins; Vitamin B Complex; Vitamin B Deficiency | 2020 |
Regulation of the parental gene GRM4 by circGrm4 RNA transcript and glutamate-mediated neurovascular toxicity in eyes.
Topics: Animals; Cystathionine beta-Synthase; Endothelial Cells; Epigenesis, Genetic; Eye; Eye Diseases; Glutamic Acid; Homocysteine; Humans; Hyperhomocysteinemia; MicroRNAs; Receptors, Metabotropic Glutamate; RNA, Circular; Vascular Diseases | 2021 |
Hyperhomocysteinemia is an emerging comorbidity in ischemic stroke.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Stroke; MAP Kinase Signaling System | 2021 |
Homocysteine and diabetes: Role in macrovascular and microvascular complications.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Diabetic Nephropathies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2021 |
The association between serum homocysteine and depression: A systematic review and meta-analysis of observational studies.
Topics: Depression; Depressive Disorder; Homocysteine; Humans; Hyperhomocysteinemia; Observational Studies as Topic; Risk Factors | 2021 |
Hyperhomocysteinemia and Cardiovascular Disease: Is the Adenosinergic System the Missing Link?
Topics: Animals; Cardiovascular Diseases; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Receptor, Adenosine A2A | 2021 |
The role of B vitamins in stroke prevention.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B 12; Vitamin B Complex | 2022 |
Homocysteine and Gliotoxicity.
Topics: Animals; Astrocytes; Gliosis; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Neuroglia | 2021 |
Current progress on the mechanisms of hyperhomocysteinemia-induced vascular injury and use of natural polyphenol compounds.
Topics: Animals; Biological Products; Homocysteine; Humans; Hyperhomocysteinemia; Polyphenols; Protective Agents; Vascular System Injuries | 2021 |
A Novel Review of Homocysteine and Pregnancy Complications.
Topics: Abortion, Habitual; Aging; Birth Weight; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2021 |
Hyperhomocysteinemia and low vitamin B12 are associated with the risk of early pregnancy loss: A clinical study and meta-analyses.
Topics: Abortion, Spontaneous; Adult; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Nutritional Physiological Phenomena; Meta-Analysis as Topic; Nutritional Status; Odds Ratio; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
Homocysteine and Age-Related Central Nervous System Diseases: Role of Inflammation.
Topics: Age Factors; Animals; Central Nervous System Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation | 2021 |
Hyperhomocysteinemia as a Link of Chemotherapy-Related Endothelium Impairment.
Topics: Animals; Atherosclerosis; Endothelium; Homocysteine; Humans; Hyperhomocysteinemia; Rats; Rats, Wistar; Trimetazidine | 2022 |
Homocysteine and Non-Cardiac Vascular Disease.
Topics: Animals; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carotid Artery Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Peripheral Arterial Disease; Vascular Diseases | 2017 |
Hyperhomocysteinaemia and vascular injury: advances in mechanisms and drug targets.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Vascular System Injuries | 2018 |
Lean Body Mass Harbors Sensing Mechanisms that Allow Safeguarding of Methionine Homeostasis.
Topics: Betaine-Homocysteine S-Methyltransferase; Biomarkers; Body Composition; Body Mass Index; Cystathionine beta-Synthase; Diet, Protein-Restricted; Dietary Proteins; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Methionine; S-Adenosylmethionine | 2017 |
Role of Hyperhomocysteinemia and Hyperuricemia in Pathogenesis of Atherosclerosis.
Topics: Animals; Atherosclerosis; Biomarkers; Cell Proliferation; Endoplasmic Reticulum Stress; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Hyperuricemia; Inflammation; Inflammation Mediators; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Risk Factors; Uric Acid | 2017 |
Hyperhomocysteinemia and cardiovascular disease in animal model.
Topics: Animals; Cardiovascular Diseases; Disease Models, Animal; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Risk Factors | 2018 |
Homocysteine in retinal artery occlusive disease: A meta-analysis of cohort studies.
Topics: Aged; Cohort Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Publication Bias; Retinal Artery Occlusion; Risk Factors; Sensitivity and Specificity | 2017 |
Dissecting the Role of 5-Lipoxygenase in the Homocysteine-Induced Alzheimer's Disease Pathology.
Topics: Alzheimer Disease; Animals; Arachidonate 5-Lipoxygenase; Brain; Epigenesis, Genetic; Homocysteine; Humans; Hyperhomocysteinemia | 2018 |
Homocysteine Levels in Autism Spectrum Disorder: A Clinical Update.
Topics: Adolescent; Adolescent Behavior; Adolescent Development; Age Factors; Autism Spectrum Disorder; Biomarkers; Child; Child Behavior; Child Development; Child, Preschool; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prognosis; Severity of Illness Index; Up-Regulation | 2018 |
[Significance of Homocysteine in Glaucoma].
Topics: Endothelium, Vascular; Epigenesis, Genetic; Exercise; Eye; Feeding Behavior; Glaucoma; Glaucoma, Open-Angle; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Nerve Degeneration; Optic Atrophy; Risk Factors; Vascular Resistance; Weight Loss | 2018 |
Homocysteine and Hyperhomocysteinaemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Avitaminosis; Cystathionine beta-Synthase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B 6 | 2019 |
Causes of hyperhomocysteinemia and its pathological significance.
Topics: Alzheimer Disease; Anemia; Animals; Biomarkers; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2018 |
Analytic Approaches for the Treatment of Hyperhomocysteinemia and Its Impact on Vascular Disease.
Topics: Animals; Betaine; Biomarkers; Cardiovascular Diseases; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Phenotype; Risk Factors; Tetrahydrofolates; Treatment Outcome | 2018 |
An evidence-based approach to globally assess the covariate-dependent effect of the MTHFR single nucleotide polymorphism rs1801133 on blood homocysteine: a systematic review and meta-analysis.
Topics: Evidence-Based Practice; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide | 2018 |
The current status of homocysteine as a risk factor for cardiovascular disease: a mini review.
Topics: Atherosclerosis; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex | 2018 |
The Effects of Homocysteine on the Skeleton.
Topics: Bone and Bones; Collagen; Folic Acid Deficiency; Glycation End Products, Advanced; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Osteoblasts; Osteoclasts; Osteoporosis; Polymorphism, Genetic; Psychotic Disorders; Vitamin B Deficiency | 2018 |
Remote ischemic conditioning as a cytoprotective strategy in vasculopathies during hyperhomocysteinemia: An emerging research perspective.
Topics: Animals; Cytokines; Endoplasmic Reticulum Stress; Homocysteine; Homocysteine S-Methyltransferase; Humans; Hyperhomocysteinemia; Inflammation; Ischemia; Mesenchymal Stem Cells; Mice; Oxidative Stress; Reactive Oxygen Species; Reperfusion; Vascular Diseases | 2019 |
Homocysteine Modification in Protein Structure/Function and Human Disease.
Topics: Animals; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2019 |
[Hyperhomocysteinemia and kidney diseases].
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases | 2018 |
Association of Elevated Plasma Homocysteine Level with Restenosis and Clinical Outcomes After Percutaneous Coronary Interventions: a Systemic Review and Meta-analysis.
Topics: Adult; Aged; Biomarkers; Coronary Restenosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Percutaneous Coronary Intervention; Risk Assessment; Risk Factors; Stents; Treatment Outcome; Up-Regulation | 2019 |
The Contribution of Homocysteine Metabolism Disruption to Endothelial Dysfunction: State-of-the-Art.
Topics: Atherosclerosis; Cardiovascular Diseases; Endothelial Cells; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Methionine; Nitric Oxide; Reactive Oxygen Species; S-Adenosylhomocysteine | 2019 |
Folic Acid and Vitamin B12 Administration in CKD, Why Not?
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Risk Factors; Vitamin B 12 | 2019 |
Disturbed homocysteine metabolism is associated with cancer.
Topics: Alleles; Animals; Cystathionine beta-Synthase; Disease Susceptibility; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Metabolic Networks and Pathways; Neoplasms; Polymorphism, Genetic; Risk Factors; Sulfur; Thromboembolism | 2019 |
Hyperhomocysteinemia and risk of incident cognitive outcomes: An updated dose-response meta-analysis of prospective cohort studies.
Topics: Alzheimer Disease; Cognition; Cognitive Dysfunction; Cohort Studies; Dementia, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Prospective Studies; Risk Factors | 2019 |
Dysregulation of Epigenetic Mechanisms of Gene Expression in the Pathologies of Hyperhomocysteinemia.
Topics: Animals; DNA Methylation; Epigenesis, Genetic; Histone Code; Homocysteine; Humans; Hyperhomocysteinemia; RNA, Untranslated | 2019 |
Implication of homocysteine in protein quality control processes.
Topics: Animals; Apoptosis; Autophagy; Cell Line; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Molecular Chaperones; Protein Aggregation, Pathological; Protein Processing, Post-Translational; Rats; Ubiquitination; Unfolded Protein Response; Vitamin B 12 | 2019 |
Synergy of homocysteine, microRNA, and epigenetics: a novel therapeutic approach for stroke.
Topics: Animals; Epigenesis, Genetic; Homocysteine; Humans; Hyperhomocysteinemia; MicroRNAs; RNA Editing; Stroke | 2013 |
The role of homocysteine in bone remodeling.
Topics: Bone Remodeling; Collagen; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinases; Mitochondria; Osteoporosis; Oxidative Stress | 2013 |
A focus on homocysteine in autism.
Topics: Animals; Autistic Disorder; Avitaminosis; Body Fluids; Cystathionine beta-Synthase; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B 6 | 2013 |
Defective homocysteine metabolism: potential implications for skeletal muscle malfunction.
Topics: Endoplasmic Reticulum Stress; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Muscle, Skeletal; Nitric Oxide; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Signal Transduction | 2013 |
Homocysteine lowering interventions for peripheral arterial disease and bypass grafts.
Topics: Arteriosclerosis; Disease Progression; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Peripheral Vascular Diseases; Randomized Controlled Trials as Topic; Tetrahydrofolates; Vascular Grafting; Vitamin B Complex | 2013 |
[Advances in the clinical and laboratory studies on methylmalonic aciduria combined with homocysteinemia type cblC].
Topics: Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Betaine; Carrier Proteins; Child; China; DNA Mutational Analysis; Gas Chromatography-Mass Spectrometry; Genotype; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Infant; Methylmalonic Acid; Mutation; Oxidoreductases; Vitamin B 12 | 2013 |
Methoxistasis: integrating the roles of homocysteine and folic acid in cardiovascular pathobiology.
Topics: Cardiovascular Diseases; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Oxidation-Reduction; Randomized Controlled Trials as Topic; Vitamin B Complex; Vitamin B Deficiency; Vitamins | 2013 |
[Homocysteine and its role in pathogenesis of Parkinson's disease and other neurodegenerative disorders].
Topics: Catechol O-Methyltransferase Inhibitors; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Neurodegenerative Diseases; Parkinson Disease; Vitamin B Complex | 2013 |
[Reconsideration of homocysteinemia].
Topics: Animals; Disease Models, Animal; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Sulfhydryl Compounds | 2013 |
The role of homocysteine-lowering B-vitamins in the primary prevention of cardiovascular disease.
Topics: Biomarkers; Cardiovascular Diseases; Down-Regulation; Homocysteine; Humans; Hyperhomocysteinemia; Primary Prevention; Risk Assessment; Risk Factors; Treatment Outcome; Vitamin B Complex | 2014 |
Hyperhomocysteinemia as a risk factor for the neuronal system disorders.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Risk Factors | 2014 |
A meta-analysis of circulating homocysteine levels in subjects with versus without abdominal aortic aneurysm.
Topics: Aortic Aneurysm, Abdominal; Biomarkers; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Odds Ratio; Risk Factors | 2015 |
[Hyperhomocysteinemia in patients with cardiovascular disease].
Topics: Cardiovascular Diseases; Causality; Comorbidity; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Myocardial Infarction; Risk Factors; Vitamin B 12 | 2014 |
Folic acid and autism: What do we know?
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Autism Spectrum Disorder; Child; Child Nutritional Physiological Phenomena; Diet; Dietary Supplements; Evidence-Based Medicine; Female; Fetal Development; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Reproducibility of Results; Risk Factors | 2016 |
Methylenetetrahydrofolate reductase C677T polymorphism, venous thrombosis, cardiovascular risk, and other effects.
Topics: Animals; Biomarkers; Comorbidity; Dietary Supplements; Gene Frequency; Genetic Predisposition to Disease; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Methylenetetrahydrofolate Reductase (NADPH2); Phenotype; Polymorphism, Genetic; Risk Assessment; Risk Factors; Treatment Outcome; Venous Thromboembolism; Vitamin B Complex | 2015 |
Mechanisms involved in the ischemic tolerance in brain: effect of the homocysteine.
Topics: Animals; Brain; Brain Ischemia; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Preconditioning | 2015 |
Homocysteine and DNA methylation: a review of animal and human literature.
Topics: Animals; Case-Control Studies; Diet; Dietary Supplements; DNA Methylation; Female; Folic Acid; Gene Knockout Techniques; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Models, Animal; Vitamin B Complex; Vitamin B Deficiency | 2014 |
Prevalence of hyperhomocysteinemia in China: a systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; China; Databases, Factual; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Sensitivity and Specificity; Young Adult | 2014 |
Role of homocysteine in the development of cardiovascular disease.
Topics: Brain; Cardiovascular Diseases; Catecholamines; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Hypothalamus; Placebos; Stroke | 2015 |
Hyperhomocysteinemia as a potential contributor of colorectal cancer development in inflammatory bowel diseases: a review.
Topics: Biomarkers; Cell Transformation, Neoplastic; Colorectal Neoplasms; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Prognosis; Risk Assessment; Risk Factors | 2015 |
Homocysteine, iron and cardiovascular disease: a hypothesis.
Topics: Biomarkers; Cardiovascular Diseases; Cystathionine; Dietary Supplements; Folic Acid; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Lipoproteins, LDL; Methionine; Risk Factors; S-Adenosylhomocysteine; Vitamin B Complex | 2015 |
Is vitamin B12 deficiency a risk factor for cardiovascular disease in vegetarians?
Topics: Cardiovascular Diseases; Diet, Vegetarian; Dietary Supplements; Homocysteine; Humans; Hyperhomocysteinemia; Prevalence; Risk Factors; Vegetarians; Vitamin B 12 Deficiency | 2015 |
Hyperhomocysteinemia: Impact on Neurodegenerative Diseases.
Topics: Animals; Biomarkers; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nutritional Status; Prognosis; Risk Factors; Vitamin B Deficiency | 2015 |
Homocysteine-Induced Endothelial Dysfunction.
Topics: Biological Availability; Cardiovascular Diseases; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Nitric Oxide; Oxidative Stress; Risk Factors; Vasodilation | 2015 |
The potential physiological crosstalk and interrelationship between two sovereign endogenous amines, melatonin and homocysteine.
Topics: Amines; Animals; Antioxidants; Biosynthetic Pathways; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Melatonin; Oxidative Stress | 2015 |
Homocysteine in ocular diseases.
Topics: Animals; Eye Diseases; Homocysteine; Humans; Hyperhomocysteinemia | 2015 |
Homocysteine excess: delineating the possible mechanism of neurotoxicity and depression.
Topics: Cysteine; Depression; Homocysteine; Humans; Hyperhomocysteinemia; Neurotoxicity Syndromes; S-Adenosylmethionine | 2015 |
Homocysteine in Chronic Kidney Disease.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylation; Oxidation-Reduction; Oxidative Stress | 2015 |
Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID).
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Disease Models, Animal; Homocysteine; Humans; Hyperhomocysteinemia | 2016 |
Homocysteine--is it still an important risk factor for cardiovascular disease?
Topics: Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors | 2015 |
[The assessment of bone quality in lifestyle-related diseases].
Topics: Arginine; Biomarkers; Bone and Bones; Bone Remodeling; Collagen; Diabetes Mellitus, Type 2; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Lysine; Osteoporosis; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Risk; Tomography, X-Ray Computed | 2016 |
Homocysteine and Mild Cognitive Impairment: Are These the Tools for Early Intervention in the Dementia Spectrum?
Topics: Brain; Cognition; Cognitive Dysfunction; Dementia; Disease Progression; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2016 |
One carbon metabolism and bone homeostasis and remodeling: A review of experimental research and population studies.
Topics: Animals; Bone and Bones; Bone Remodeling; Carbon; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Osteoblasts; Osteoclasts; Vitamin B 12; Vitamin B Deficiency | 2016 |
Interventions for lowering plasma homocysteine levels in dialysis patients.
Topics: Aged; Cardiovascular Diseases; Cause of Death; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Renal Dialysis; Stroke; Venous Thrombosis; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2016 |
Interactions of hyperhomocysteinemia and T cell immunity in causation of hypertension.
Topics: Animals; Biomarkers; Blood Pressure; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Immunity, Cellular; Inflammation Mediators; Lymphocyte Activation; Prognosis; Risk Assessment; Risk Factors; Signal Transduction; T-Lymphocytes; Up-Regulation | 2017 |
Homocysteine, B Vitamins, and Cognitive Impairment.
Topics: Aging; Animals; Biomarkers; Cerebrovascular Circulation; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nootropic Agents; Nutritional Status; Practice Guidelines as Topic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
The Molecular and Cellular Effect of Homocysteine Metabolism Imbalance on Human Health.
Topics: Bone Diseases; Cardiovascular Diseases; Cerebrovascular Disorders; Gastrointestinal Diseases; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Neoplasms; Oxidation-Reduction; Oxidative Stress; Risk Factors | 2016 |
Homocysteine, Alcoholism, and Its Potential Epigenetic Mechanism.
Topics: Alcoholism; Animals; Epigenesis, Genetic; Ethanol; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Models, Biological; Models, Neurological | 2016 |
Homocysteine as a Pathological Biomarker for Bone Disease.
Topics: Animals; Biomarkers; Bone and Bones; Bone Remodeling; Chondrocytes; Collagen; Disease Progression; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinases; Mitochondria; Osteoclasts; Osteogenesis; Osteoporosis; Oxidative Stress; Regional Blood Flow | 2017 |
Determinants of hyperhomocysteinemia in healthy and hypertensive subjects: A population-based study and systematic review.
Topics: Blood Pressure; Body Mass Index; China; Creatinine; Diet, Healthy; Dietary Supplements; Exercise; Female; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Life Style; Male; Risk Factors; Triglycerides; Uric Acid; Vegetables; Vitamin B Complex | 2017 |
Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy.
Topics: Animals; DNA Methylation; Epigenesis, Genetic; Folic Acid; Histones; Homocysteine; Humans; Hyperhomocysteinemia; Metformin; Muscle, Skeletal; Muscular Diseases; Oxidative Stress; RNA Interference; Thiazolidinediones; Vitamin B 12; Vitamin B 6 | 2017 |
The Sulfur Metabolite Lanthionine: Evidence for a Role as a Novel Uremic Toxin.
Topics: Alanine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Renal Dialysis; Sulfides; Uremia | 2017 |
Homocysteine levels and risk of essential hypertension: A meta-analysis of published epidemiological studies.
Topics: Essential Hypertension; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Odds Ratio; Publication Bias; Risk Factors | 2017 |
Murine models of hyperhomocysteinemia and their vascular phenotypes.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Genetic Predisposition to Disease; Homocysteine; Hyperhomocysteinemia; Mice; Phenotype; Thrombosis | 2008 |
Hyperhomocysteinemia: no longer a consideration in the management of venous thromboembolism.
Topics: Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Polymorphism, Genetic; Risk Factors; Venous Thromboembolism | 2008 |
Public health significance of elevated homocysteine.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neural Tube Defects; Pregnancy; Public Health; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
The worldwide challenge of the dementias: a role for B vitamins and homocysteine?
Topics: Aged; Aged, 80 and over; Aging; Dementia; Environment; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B Complex | 2008 |
Hyperhomocysteinemia and lower extremity wounds.
Topics: Blood Coagulation; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Lower Extremity; Myocytes, Smooth Muscle; Platelet Aggregation; Risk Factors; Varicose Ulcer; Wounds and Injuries | 2008 |
[Homocysteine metabolism disorders as a potential predictor of preeclamsia].
Topics: Biomarkers; Female; Health Knowledge, Attitudes, Practice; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Welfare; Pre-Eclampsia; Pregnancy; Prenatal Care; Primary Prevention; Risk Assessment; Risk Factors | 2008 |
Homocysteine and heart failure: an overview.
Topics: Animals; Clinical Trials as Topic; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Vascular Diseases; Vitamin B 12 Deficiency | 2009 |
Protective effect of vitamin B therapy on bone and cardiovascular disease.
Topics: Bone Diseases; Cardiovascular Diseases; Clinical Trials as Topic; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Vitamin B Complex | 2009 |
Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cross-Sectional Studies; England; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multicenter Studies as Topic; Mutation; Odds Ratio; Peripheral Vascular Diseases; Phenotype; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Risk Assessment | 2009 |
Bone tissue and hyperhomocysteinemia.
Topics: Animals; Bone and Bones; Bone Density; Bone Remodeling; Disease Models, Animal; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Osteoporosis | 2009 |
The pathophysiological hypothesis of homocysteine thiolactone-mediated vascular disease.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cystathionine beta-Synthase; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Methionine-tRNA Ligase; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Thrombosis; Vascular Diseases | 2008 |
[Present role of homocysteine in clinical medicine].
Topics: Adolescent; Adult; Cardiovascular Diseases; Child; Child, Preschool; Ectopia Lentis; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Life Style; Male; Middle Aged; Myopia; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Quo vadis: whither homocysteine research?
Topics: Animals; Cardiovascular Diseases; Clinical Trials as Topic; Homocysteine; Humans; Hyperhomocysteinemia | 2009 |
Hyperhomocysteinemia and sudden cardiac death: potential arrhythmogenic mechanisms.
Topics: Animals; Arrhythmias, Cardiac; Calcium Signaling; Connexins; Coronary Disease; Death, Sudden, Cardiac; Dietary Supplements; Heart; Heart Conduction System; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinases; Myocardium; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; Risk Factors; Vitamin B Complex | 2010 |
Homocysteine levels and amyotrophic lateral sclerosis: A possible link.
Topics: Amyotrophic Lateral Sclerosis; Animals; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Risk Factors | 2010 |
Stroke: roles of B vitamins, homocysteine and antioxidants.
Topics: Antioxidants; Avitaminosis; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vegetables; Vitamin B Complex; Vitamins | 2009 |
Homocysteine and peripheral arterial disease: systematic review and meta-analysis.
Topics: Aged; Aged, 80 and over; Biomarkers; Dietary Supplements; Evidence-Based Medicine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Peripheral Vascular Diseases; Treatment Outcome; Up-Regulation | 2009 |
[Nutrition and bone health. Roles of vitamin C and vitamin B as regulators of bone mass and quality].
Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Bone Density; Collagen; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex; Vitamin B Deficiency | 2009 |
Molecular mechanisms of homocysteine toxicity.
Topics: Animals; Apoptosis; Blood Cells; Cardiovascular Diseases; Carnosine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neurodegenerative Diseases; Neurons; Pregnancy; Receptors, N-Methyl-D-Aspartate; Risk Factors | 2009 |
Stable-isotope dilution LC-ESI-MS/MS techniques for the quantification of total homocysteine in human plasma.
Topics: Carotid Artery Thrombosis; Chromatography, Liquid; Homocysteine; Humans; Hyperhomocysteinemia; Indicator Dilution Techniques; Isotope Labeling; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Hyperhomocysteinemia: a biochemical link between bone and cardiovascular system diseases?
Topics: Animals; Biomarkers; Bone and Bones; Bone Diseases; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia | 2009 |
[Hyperhomocysteinemia and cardiometabolic risk].
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Deficiency; Vitamins | 2009 |
[Homocysteine: a casual link with heart failure?].
Topics: Animals; Biomarkers; Evidence-Based Medicine; Heart Failure; Heart Failure, Systolic; Homocysteine; Humans; Hyperhomocysteinemia; Myocardium; Prognosis; Risk Factors; Severity of Illness Index | 2009 |
Polymorphism of genes encoding homocysteine metabolism-related enzymes and risk for cardiovascular disease.
Topics: Cardiovascular Diseases; Enzymes; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Physiological Phenomena; Polymorphism, Genetic; Risk Factors; Vitamins | 2009 |
Postgraduate Symposium: The MTHFR C677T polymorphism, B-vitamins and blood pressure.
Topics: Blood Pressure; Clinical Trials as Topic; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Hypertension; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Riboflavin; Risk Factors; Stroke; Vitamin B Complex | 2010 |
The controversial role of B-vitamins in cardiovascular risk: An update.
Topics: Biomarkers; Cardiovascular Diseases; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Risk Assessment; Risk Factors; Treatment Outcome; Vitamin B Complex | 2009 |
Genetics of homocysteine metabolism and associated disorders.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Dehydrogenase (NAD+); Severity of Illness Index; Vitamin B 12; Vitamin B 6 | 2010 |
[Hyperhomocysteinemia and the disturbance of haemostasis--facts and mythes].
Topics: Animals; Cardiovascular Diseases; Hemostasis; Hemostatic Disorders; Homocysteine; Humans; Hyperhomocysteinemia | 2009 |
Homocysteine, vitamin determinants and neurological diseases.
Topics: Avitaminosis; Homocysteine; Humans; Hyperhomocysteinemia; Nervous System Diseases; Polymorphism, Genetic; Vascular Diseases; Vitamin B Complex | 2010 |
[Disturbances of homocysteine metabolism as a risk factor of cardiovascular diseases development: effect on prognosis and possibilities of correction with drugs].
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Prognosis; Risk Factors; Russia; Vitamin B Complex | 2010 |
Homocysteine and arterial thrombosis: Challenge and opportunity.
Topics: Animals; Biomarkers; Clinical Trials as Topic; Coronary Thrombosis; Diagnostic Tests, Routine; Diet Therapy; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Platelet Activation; Prognosis; Reactive Oxygen Species; Risk Factors; Vitamins | 2010 |
Homocysteine to hydrogen sulfide or hypertension.
Topics: Calcium; Collagen; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Hypertension; Muscle, Smooth, Vascular; Nitric Oxide | 2010 |
Fenofibrate, homocysteine and renal function.
Topics: Animals; Biomarkers; Creatinine; Disease Progression; Dyslipidemias; Fenofibrate; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Kidney; PPAR alpha; Renal Insufficiency; Risk Factors; Sulfhydryl Compounds | 2010 |
The homocysteine controversy.
Topics: Animals; Dissent and Disputes; Epidemiologic Research Design; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mendelian Randomization Analysis; Models, Biological; Severity of Illness Index; Vitamin B Complex | 2011 |
[CKD-MBD (Chronic Kidney Disease-Mineral and Bone Disorder). Bone quality in chronic kidney disease : enzymatic and non-enzymatic glycation or oxidation induced cross-links in bone].
Topics: Animals; Arginine; Bone and Bones; Bone Diseases, Metabolic; Chronic Disease; Collagen; Fractures, Bone; Glycation End Products, Advanced; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Lysine; Osteoporosis; Oxidative Stress; Risk | 2010 |
Is a low blood level of vitamin B12 a cardiovascular and diabetes risk factor? A systematic review of cohort studies.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Meta-Analysis as Topic; Risk Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Homocysteine, intracellular signaling and thrombotic disorders.
Topics: Animals; Blood Platelets; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Signal Transduction; Thrombosis; Vascular Diseases | 2010 |
Homocysteine in vascular Behcet disease: a meta-analysis.
Topics: Adult; Behcet Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thrombosis | 2010 |
Teratogenicity and underlying mechanisms of homocysteine in animal models: a review.
Topics: Abnormalities, Drug-Induced; Animals; Chickens; Congenital Abnormalities; Embryonic Development; Female; Fetal Development; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Neural Crest; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Rats; Teratogens | 2010 |
Hyperhomocysteinemia in L-dopa treated patients with Parkinson's disease: potential implications in cognitive dysfunction and dementia?
Topics: Antiparkinson Agents; Cognition Disorders; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Neurons; Parkinson Disease | 2010 |
Iatrogenic hyperhomocysteinemia in patients with metabolic syndrome: a systematic review and metaanalysis.
Topics: Administration, Oral; Aged; Antihypertensive Agents; Clinical Trials as Topic; Fibric Acids; Homocysteine; Humans; Hydrochlorothiazide; Hyperhomocysteinemia; Hyperlipidemias; Hypoglycemia; Iatrogenic Disease; Metabolic Syndrome; Metformin; Middle Aged | 2011 |
Homocysteine in neurological disease: a marker or a cause?
Topics: Biomarkers; Cell Death; Homocysteine; Humans; Hyperhomocysteinemia; Molecular Targeted Therapy; Nervous System Diseases; Neurons; Risk Factors | 2011 |
Homocysteine, cardiovascular inflammation, and myocardial remodeling.
Topics: Animals; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Ventricular Remodeling | 2010 |
Mechanisms of cardiovascular remodeling in hyperhomocysteinemia.
Topics: Animals; Cardiovascular Diseases; Cardiovascular System; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinases; Methionine; Nitric Oxide Synthase; Oxidation-Reduction; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species | 2011 |
The homocysteine hypothesis: still relevant to the prevention and treatment of cardiovascular disease?
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Primary Prevention; Vitamin B 6; Vitamin B Complex | 2010 |
Hyper-homocysteinemia: a novel risk factor or a powerful marker for cardiovascular diseases? Pathogenetic and therapeutical uncertainties.
Topics: Acute Disease; Biomarkers; Cardiovascular Diseases; Chronic Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2011 |
[Disturbances of folic acid and homocysteine metabolism in alcohol abuse].
Topics: Acute Coronary Syndrome; Alcoholism; Anemia, Megaloblastic; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases; Malnutrition | 2011 |
Quality control in tRNA charging -- editing of homocysteine.
Topics: Amino Acyl-tRNA Synthetases; Animals; Brain Diseases; Catalytic Domain; Escherichia coli; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Substrate Specificity; Transfer RNA Aminoacylation; Vascular Diseases | 2011 |
Is hyperhomocysteinemia an Alzheimer's disease (AD) risk factor, an AD marker, or neither?
Topics: Alzheimer Disease; Animals; Biomarkers; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2011 |
Meta-analysis: hyperhomocysteinaemia in inflammatory bowel diseases.
Topics: Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Genetic; Risk Factors; Thromboembolism | 2011 |
[Advances in studies on the protein homocysteinylation].
Topics: Animals; Atherosclerosis; Homocysteine; Humans; Hyperhomocysteinemia; Protein Binding; Protein Denaturation; Protein Processing, Post-Translational; Proteins | 2011 |
Enzymatic and non-enzymatic antioxidative effects of folic acid and its reduced derivates.
Topics: Animals; Antioxidants; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress | 2012 |
Maternal homocysteine and small-for-gestational-age offspring: systematic review and meta-analysis.
Topics: Birth Weight; Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Infant, Small for Gestational Age; Odds Ratio; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 2012 |
Mitochondrial mitophagic mechanisms of myocardial matrix metabolism and remodelling.
Topics: Animals; Autophagy; Calcium; Extracellular Matrix; Fibrinolysin; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinases; Mice; Mitochondria, Heart; Myocardium; Myocytes, Cardiac; Oxidative Stress; Permeability; Peroxisome Proliferator-Activated Receptors; Plasminogen; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger; Ventricular Remodeling | 2012 |
Homocysteine-lowering therapy does not lead to reduction in cardiovascular outcomes in chronic kidney disease patients: a meta-analysis of randomised, controlled trials.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Randomized Controlled Trials as Topic | 2012 |
[The role of homocysteine and methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase polymorphisms in the development of cardiovascular diseases and hypertension].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cardiovascular Diseases; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide | 2012 |
Expanding roles of glutamate receptors in neurovascular regulation.
Topics: Cardiovascular Diseases; Endothelial Cells; Glutamic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurons; Receptors, Glutamate | 2012 |
The disturbance of hemostasis induced by hyperhomocysteinemia; the role of antioxidants.
Topics: Animals; Antioxidants; Blood Platelets; Blood Vessels; Endothelial Cells; Fibrinolysis; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia | 2012 |
Paraoxonase 1 and homocysteine metabolism.
Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Atherosclerosis; Coronary Artery Disease; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipoproteins, HDL; Mice; Oxidative Stress; Stroke | 2012 |
[Homocysteine, vitamin B-12, folic acid and the cognitive decline in the elderly].
Topics: Aged; Brain; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nutritional Physiological Phenomena; Receptors, N-Methyl-D-Aspartate; Risk Factors; Vitamin B 12 | 2013 |
Role of homocysteine in end-stage renal disease.
Topics: Animals; Dialysis; Homocysteine; Humans; Hyperglycemia; Hyperhomocysteinemia; Kidney; Kidney Failure, Chronic; Meta-Analysis as Topic; Renal Dialysis | 2012 |
Antiepileptic drugs, hyperhomocysteinemia and B-vitamins supplementation in patients with epilepsy.
Topics: Anticonvulsants; Epilepsy; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2012 |
[Kynurenic acid--a new tool in the treatment of hiperhomocysteinemia and its consequences?].
Topics: Atherosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Kynurenic Acid; Stroke; Tissue Distribution | 2012 |
The year in atherothrombosis.
Topics: Animals; Atherosclerosis; Biomarkers; Cardiovascular Agents; Diabetes Complications; Dyslipidemias; Early Diagnosis; Fibrinolytic Agents; Global Health; Health Behavior; Health Care Costs; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Hypertension; Magnetic Resonance Imaging; Medication Adherence; Plaque, Atherosclerotic; Risk Factors; Risk Reduction Behavior; Stents; Thrombosis; United States | 2012 |
Updating the relationship between hyperhomocysteinemia lowering therapy and cardiovascular events.
Topics: Animals; Biomarkers; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Treatment Outcome | 2013 |
Methylenetetrahydrofolate reductase: biochemical characterization and medical significance.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Arabidopsis; Cardiovascular Diseases; Catalysis; Escherichia coli; Homocysteine; Humans; Hyperhomocysteinemia; Leishmania major; Mental Disorders; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; Molecular Sequence Data; Neoplasms; Neural Tube Defects; Polymorphism, Single Nucleotide; Sequence Alignment; Tetrahydrofolates | 2013 |
Homocysteine imbalance: a pathological metabolic marker.
Topics: Biomarkers; Epigenesis, Genetic; Health; Homocysteine; Humans; Hyperhomocysteinemia; Methylation | 2012 |
Lowering homocysteine levels with folic acid and B-vitamins do not reduce early atherosclerosis, but could interfere with cognitive decline and Alzheimer's disease.
Topics: Alzheimer Disease; Atherosclerosis; Cognition; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2013 |
Homocysteine, heat shock proteins, genistein and vitamins in ischemic stroke--pathogenic and therapeutic implications.
Topics: Dietary Supplements; Genistein; Heat-Shock Proteins; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Vitamins | 2012 |
Plasma total homocysteine status of vegetarians compared with omnivores: a systematic review and meta-analysis.
Topics: Adult; Cohort Studies; Cross-Sectional Studies; Diet; Diet, Vegetarian; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Hyperhomocysteinemia in renal transplant recipients.
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Risk Factors | 2002 |
Methods for measuring sulfur amino acid metabolism.
Topics: Amino Acids, Sulfur; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kinetics; Methionine; Methylation; Models, Biological; Radioisotope Dilution Technique; Vitamin B 12 | 2002 |
Homocysteine and its role in the pathogenesis of atherosclerotic vascular disease.
Topics: Arteriosclerosis; Clinical Trials as Topic; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Muscle, Smooth, Vascular; Risk Factors | 2002 |
Plasma homocysteine levels and cardiovascular risk in Indians.
Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; India; Risk Factors | 2002 |
Homocysteine and hypertension.
Topics: Age Factors; Diabetes Complications; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Risk Factors; Vascular Diseases | 2002 |
Role of nutritional supplementation in reducing the levels of homocysteine.
Topics: Dietary Supplements; Homocysteine; Humans; Hyperhomocysteinemia; India; Reference Values; Vitamin B Deficiency | 2002 |
Homocysteine, MTHFR 677C-->T polymorphism, and risk of ischemic stroke: results of a meta-analysis.
Topics: Brain Ischemia; Case-Control Studies; Cohort Studies; Comorbidity; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prevalence; Prospective Studies; Retrospective Studies; Risk Assessment; Stroke | 2002 |
Homocysteine: an aetiological contributor to peripheral vascular arterial disease.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Peripheral Vascular Diseases | 2002 |
In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions.
Topics: Deuterium Oxide; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Kidney Failure, Chronic; Methionine; Methylation; Serine; Tomography, Emission-Computed; Tritium | 2002 |
Hyperhomocyst(e)inemia and Thrombophilia.
Topics: Blood Coagulation Tests; Homocysteine; Humans; Hyperhomocysteinemia; Practice Guidelines as Topic; Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Thromboembolism; Thrombophilia; Venous Thrombosis | 2002 |
Pharmacotherapy of hyperhomocysteinaemia in patients with thrombophilia.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Pyridoxine; Renal Insufficiency; Thrombophilia; Vitamin B 12; Vitamins | 2002 |
Hyperhomocysteinemia and transplant coronary artery disease.
Topics: Animals; Coronary Disease; Folic Acid; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine | 2002 |
Behçet's disease--current status.
Topics: Angiogenesis Inhibitors; Azathioprine; Behcet Syndrome; C-Reactive Protein; Drug Therapy, Combination; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Inflammation; Interferon alpha-2; Interferon-alpha; Recombinant Proteins | 2002 |
Homocysteine, folate deficiency, and Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Parkinson Disease; Risk Factors | 2002 |
[Clinical relevance of homocysteine monitoring in the diabetic patient].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Monitoring, Physiologic | 2002 |
Homocysteine and blood pressure.
Topics: Animals; Arteries; Blood Pressure; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin Resistance; Kidney | 2003 |
Genetics of hyperhomocysteinaemia in cardiovascular disease.
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Models, Biological; Polymorphism, Genetic | 2003 |
[Hyperhomocysteinemia and thrombosis: clinical case and literature's review].
Topics: Adult; Femoral Artery; Homocysteine; Humans; Hyperhomocysteinemia; Male; Popliteal Artery; Thromboembolism; Treatment Outcome | 2002 |
The methionine-homocysteine cycle and its effects on cognitive diseases.
Topics: Alzheimer Disease; Cardiovascular Diseases; Cognition Disorders; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Memory Disorders; Methionine; Methionine Adenosyltransferase; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2003 |
Homocysteine in uremia.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Uremia | 2003 |
Hyperhomocysteinemia and thrombosis.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Thrombosis | 2003 |
Reducing coronary artery disease by decreasing homocysteine levels.
Topics: Coronary Disease; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Nurse's Role; Patient Education as Topic; Primary Prevention; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
[Cellular and molecular mechanism of cardiovascular disease resulting from hyperhomocysteinemia].
Topics: Animals; Arteriosclerosis; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Rats | 2002 |
Hyperhomocysteinemia, vascular function and atherosclerosis: effects of vitamins.
Topics: Arteriosclerosis; Avitaminosis; Coronary Disease; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney Failure, Chronic; Methionine; Risk Factors; Thrombosis; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamins | 2002 |
Homocysteine, renal function, and risk of cardiovascular disease.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Prospective Studies; Risk Factors; Stroke | 2003 |
Potential strategies to normalize the levels of homocysteine in chronic renal failure patients.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Uremia | 2003 |
Possible mechanisms of homocysteine toxicity.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Toxins, Biological; Uremia | 2003 |
Genetic determinants of the homocysteine level.
Topics: Antigens, Surface; Carboxypeptidases; Carrier Proteins; Glutamate Carboxypeptidase II; Homocysteine; Humans; Hyperhomocysteinemia; Membrane Proteins; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Transcobalamins | 2003 |
Plasma homocysteine and arterial thromboembolic disease.
Topics: Arterial Occlusive Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thromboembolism | 2003 |
Homocysteine and pregnancy.
Topics: Female; Homocysteine; Humans; Hyperhomocysteinemia; Neural Tube Defects; Placenta Diseases; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic | 2003 |
Homocysteine and atherothrombosis: diagnosis and treatment.
Topics: Arteriosclerosis; Coronary Disease; Endothelium, Vascular; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidative Stress; Polymorphism, Genetic; Thrombosis | 2003 |
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].
Topics: Animals; Arteriosclerosis; Biomarkers; Cystathionine beta-Synthase; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Nitric Oxide; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Rats; Risk Factors; S-Adenosylmethionine; Signal Transduction; Thrombophilia; Vascular Diseases; Vasodilation; Vitamin B 6 Deficiency | 2003 |
Homocysteine and Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Homocysteine; Hyperhomocysteinemia; Risk Factors | 2003 |
Hyperhomocysteinemia: genetic determinants and selected mouse models.
Topics: Adenosine Deaminase; Animals; Disease Models, Animal; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Models, Biological; Polymorphism, Genetic; Time Factors | 2003 |
[How to treat and manage hyperhomocysteinemia].
Topics: Diabetes Complications; Homocysteine; Humans; Hyperhomocysteinemia; Vascular Diseases | 2003 |
[Homocysteine and coronary artery disease].
Topics: Coronary Artery Disease; Dietary Supplements; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2003 |
Potential role for adenosine in the pathogenesis of the vascular complications of hyperhomocysteinemia.
Topics: Adenosine; Cardiovascular Diseases; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Receptors, Purinergic P1; S-Adenosylhomocysteine | 2003 |
Hyperhomocysteinemia and its role in the development of atherosclerosis.
Topics: Animals; Aorta; Arteriosclerosis; Chemokine CCL2; Diet; Endoplasmic Reticulum; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Models, Animal; Oxidative Stress; Risk Factors | 2003 |
[Hyperhomocysteinemia during pregnancy as a risk factor of preeclampsia].
Topics: Carbohydrate Metabolism; Female; Homocysteine; Humans; Hyperhomocysteinemia; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors; Ultrasonography, Doppler; Uterus | 2003 |
Changes in haemostasis during normal pregnancy: does homocysteine play a role in maintaining homeostasis?
Topics: Female; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Neural Tube Defects; Placenta Diseases; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Thromboembolism | 2003 |
Implications of oxidative stress and homocysteine in the pathophysiology of essential hypertension.
Topics: Animals; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Oxidative Stress | 2003 |
Hyperhomocysteinemia in heart transplantation: from bench to bedside.
Topics: Coronary Artery Disease; Female; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Postoperative Complications | 2003 |
[Hyperhomocysteinemia and cardiovascular risk in diabetes mellitus].
Topics: Adult; Arteriosclerosis; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Thrombophilia | 2003 |
Homocysteine and essential hypertension.
Topics: Antioxidants; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Muscle, Smooth, Vascular; Nitric Oxide; Vitamin B 12 | 2003 |
[Homocysteine as a coronary risk factor].
Topics: Alcoholic Beverages; Arteriosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Disease; Diet; Female; Folic Acid; Glycine max; Homocysteine; Humans; Hyperhomocysteinemia; Male; Platelet Aggregation; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
[Public health control of hyperhomocysteinemia and its consequences].
Topics: Alzheimer Disease; Canada; Cardiovascular Diseases; Flour; Folic Acid; Food, Fortified; Hematinics; Homocysteine; Humans; Hungary; Hyperhomocysteinemia; Neoplasms; Neural Tube Defects; Primary Prevention; Public Health; Randomized Controlled Trials as Topic; United Kingdom; United States; Vitamin B Complex; Vitamin B Deficiency | 2003 |
Update on cobalamin, folate, and homocysteine.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Metabolism, Inborn Errors; Polymorphism, Genetic; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
DACH-LIGA homocystein (german, austrian and swiss homocysteine society): consensus paper on the rational clinical use of homocysteine, folic acid and B-vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations.
Topics: Austria; Cardiovascular Diseases; Female; Folic Acid; Germany; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Switzerland; Thrombosis; Vitamin B 12; Vitamin B 6 | 2003 |
Does homocysteine cause hypertension?
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Metabolic Syndrome; Pyridoxine | 2003 |
Hyperhomocysteinemia and B-vitamin deficiencies in infants and children.
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Vitamin B 12 Deficiency | 2003 |
The role of genetic factors in the development of hyperhomocysteinemia.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Aged, 80 and over; Aging; Catechol O-Methyltransferase; Diet, Vegetarian; Folic Acid Deficiency; Genotype; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Mutation; Thymidylate Synthase; Transcobalamins; Vitamin B 12 Deficiency | 2003 |
Hyperhomocysteinemia and immune activation.
Topics: Cytokines; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Reactive Oxygen Species; Vascular Diseases | 2003 |
Interactions of homocysteine, nitric oxide, folate and radicals in the progressively damaged endothelium.
Topics: Endothelium, Vascular; Folic Acid; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Nitric Oxide; Vascular Diseases | 2003 |
Influence of hyperhomocysteinemia on the cellular redox state--impact on homocysteine-induced endothelial dysfunction.
Topics: Animals; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Vascular Diseases | 2003 |
Homocysteine and oxidative stress.
Topics: Animals; Cardiovascular Diseases; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Lipoproteins, LDL; Models, Biological; Oxidative Stress; Risk Factors; Superoxide Dismutase | 2003 |
The association of homocysteine and coronary artery disease.
Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2003 |
Correlation between C677T MTHFR gene polymorphism, plasma homocysteine levels and the incidence of CAD.
Topics: Clinical Trials as Topic; Coronary Artery Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Polymorphism, Genetic; Prevalence | 2001 |
Folate, homocysteine, endothelial function and cardiovascular disease.
Topics: Antioxidants; Cardiovascular Diseases; Endothelium, Vascular; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Risk Factors; Vitamin B Complex | 2004 |
Homocysteine and post-angioplasty restenosis.
Topics: Angioplasty, Balloon, Coronary; Coronary Restenosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Postoperative Complications; Risk Factors | 2003 |
The effect of fibrates and other lipid-lowering drugs on plasma homocysteine levels.
Topics: Fenofibrate; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypolipidemic Agents; Niacin; Risk Factors; Simvastatin | 2004 |
Homocysteine and cardiovascular disease in renal disease.
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases | 2003 |
Homocysteine and cardiovascular disease.
Topics: Arteriosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Endothelium, Vascular; Genetic Variation; Homocysteine; Humans; Hyperhomocysteinemia | 2004 |
Lipids and atherosclerosis.
Topics: Arteriosclerosis; Chemokines; Cholesterol; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Lipoproteins, LDL; Risk Factors | 2004 |
[Homocysteine and neuropsychiatric disorders].
Topics: Alzheimer Disease; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mental Disorders; Parkinson Disease; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6 | 2004 |
Homocysteine-induced thrombosis.
Topics: Adult; Aged; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Thrombosis | 2004 |
Homocysteine metabolism in renal failure.
Topics: DNA Methylation; Homocysteine; Humans; Hyperhomocysteinemia; Renal Insufficiency | 2004 |
Homocysteine as a neurotoxin in chronic alcoholism.
Topics: Alcoholism; Animals; Apoptosis; Central Nervous System Depressants; Ethanol; Homocysteine; Humans; Hyperhomocysteinemia; Neurotoxins; Receptors, Glutamate | 2004 |
[Homocysteine and Alzheimer's disease].
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Homocysteine; Humans; Hyperhomocysteinemia | 2004 |
[Hyperhomocysteinemia and pregnancy complications].
Topics: Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Patient Education as Topic; Pregnancy; Pregnancy Complications; Pregnancy, High-Risk; Risk Factors | 2004 |
New cardiovascular risk factors: homocysteine and vitamins involved in homocysteine metabolism.
Topics: Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamins | 2004 |
Homocysteine and cardiovascular disease: biological mechanisms, observational epidemiology, and the need for randomized trials.
Topics: Cardiovascular Diseases; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2004 |
Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease.
Topics: Animals; Apoptosis; Arteriosclerosis; Cardiovascular Diseases; Cell Adhesion; Endoplasmic Reticulum; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Models, Biological; Oxidative Stress; Protein Folding; Risk Factors; Thrombosis; Transcription Factors | 2004 |
Clinical use and rational management of homocysteine, folic acid, and B vitamins in cardiovascular and thrombotic diseases.
Topics: Cardiovascular Diseases; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Patient Care Management; Practice Guidelines as Topic; Thrombosis; Vitamin B Complex | 2004 |
Homocysteine and carotid intima-media thickness: a critical appraisal of the evidence.
Topics: Carotid Artery Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Tunica Intima; Tunica Media | 2004 |
[Consequences of moderate hyperhomocysteinemia in internal medicine].
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2004 |
Homocysteine and levodopa: should Parkinson disease patients receive preventative therapy?
Topics: Antiparkinson Agents; Arteriosclerosis; Catechol O-Methyltransferase; Dementia; Disease Progression; Disease Susceptibility; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Levodopa; Models, Biological; Multicenter Studies as Topic; Oxidative Stress; Parkinson Disease; Randomized Controlled Trials as Topic; Substantia Nigra | 2004 |
[Hyperhomocysteinemia: from theory and practice in the treatment of thrombophilias].
Topics: Administration, Oral; Anticoagulants; Blood Coagulation Tests; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Marfan Syndrome; Multicenter Studies as Topic; Mutation; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Risk Factors; Thrombophilia; Time Factors; Venous Thrombosis; Vitamin B 12; Vitamin B 6 | 2004 |
Homocysteine: is it a clinically important cardiovascular risk factor?
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Myocardial Infarction; Reference Values; Risk Factors; Vitamin B Complex | 2004 |
[Homocysteine as the factor of atherosclerosis risk].
Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia | 2004 |
[Homocysteine--an underestimated atheromatosis risk factor. Do sex hormones influence homocysteine concentrations?].
Topics: Atherosclerosis; Cardiovascular Diseases; Comorbidity; Female; Gonadal Steroid Hormones; Homocysteine; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Insulin; Menopause; Obesity; Risk Factors | 2004 |
Homocysteine remethylation and trans-sulfuration.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Sulfur | 2004 |
Mapping the theories of preeclampsia: the role of homocysteine.
Topics: Adult; Age Factors; Biomarkers; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Maternal Age; Parity; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Primary Prevention; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Survival Rate; Vitamin B 12 | 2005 |
Hyperhomocysteinemia, thrombosis and vascular biology.
Topics: Animals; Blood Coagulation; Blood Vessels; Cells, Cultured; Extracellular Matrix; Fibrinolysis; Folic Acid Deficiency; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Platelet Activation; Rats; Risk; Thrombelastography; Thrombosis; Time Factors; Vascular Diseases | 2004 |
Role of hyperhomocysteinemia in aortic disease.
Topics: Aged; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Diseases; Collagen; Disease Progression; Extracellular Matrix; Female; Fibrillin-1; Fibrillins; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Marfan Syndrome; Microfilament Proteins; Middle Aged; Risk; Thrombosis; Vascular Diseases | 2004 |
The potential role of homocysteine in percutaneous coronary interventions (PCI): review of current evidence and plausibility of action.
Topics: Adult; Aged; Angioplasty; Angioplasty, Balloon, Coronary; Animals; Clinical Trials as Topic; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Stenosis; Endothelium, Vascular; Female; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Middle Aged; Models, Biological; Risk; Risk Factors; Vitamin B Complex | 2004 |
What is new in vitamin B(12)?
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Intestinal Absorption; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Asymmetric dimethyl-L-arginine (ADMA): a possible link between homocyst(e)ine and endothelial dysfunction.
Topics: Animals; Arginine; Arteriosclerosis; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Nitric Oxide; Vascular Diseases | 2005 |
Mechanisms of increased vascular oxidant stress in hyperhomocys-teinemia and its impact on endothelial function.
Topics: Animals; Antioxidants; Blood Vessels; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Superoxides | 2005 |
Metabolism of homocysteine and its relationship with cardiovascular disease.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 2004 |
[Hyperhomocysteinemia as a clinical manifestation of thrombosis risk].
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Mutation; Risk Factors; Thrombosis | 2005 |
Hyperhomocysteinemia and atherosclerosis.
Topics: Animals; Atherosclerosis; Cystathionine beta-Synthase; Homocysteine; Humans; Hyperhomocysteinemia; Reactive Oxygen Species | 2005 |
B-vitamins, homocysteine metabolism and CVD.
Topics: Carbon-Nitrogen Ligases; Cardiovascular Diseases; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Polymorphism, Genetic; Risk Factors; Vitamin B Complex; Vitamin B Deficiency | 2004 |
Homocysteine, the bad thiol.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases; Sulfhydryl Compounds | 2005 |
[Determination and utilisation of the plasmatic concentration of homocysteine in clinical practice].
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2005 |
Health implications of homocysteine and folates: possible preventive measures.
Topics: Aging; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Preventive Medicine; Risk Factors; Sex Characteristics | 2005 |
Is homocysteine important as risk factor for coronary heart disease?
Topics: Aging; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prospective Studies; Risk Factors; Sex Characteristics | 2005 |
[Endothelial function and ischemic heart disease].
Topics: Arteritis; Brachial Artery; Cell Adhesion Molecules; Coronary Angiography; Cytokines; Endothelium, Vascular; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Hypertension; Infections; Inflammation; Laser-Doppler Flowmetry; Lipoproteins, LDL; Monocytes; Myocardial Ischemia; Oxidation-Reduction; Platelet Adhesiveness; Platelet Aggregation; Risk Factors; Ultrasonography; Vasodilation | 2005 |
Is Hyperhomocyst(e)inemia a humoral predictor of coronary heart disease?
Topics: Clinical Trials as Topic; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Meta-Analysis as Topic; Predictive Value of Tests; Risk Factors | 2005 |
Increase in plasma homocysteine levels induced by drug treatments in neurologic patients.
Topics: Cerebrovascular Disorders; Epilepsy; Homocysteine; Humans; Hyperhomocysteinemia; Parkinson Disease; Vitamins | 2005 |
Homocysteine in microvascular endothelial cell barrier permeability.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Endothelium, Vascular; Extracellular Matrix; Homocysteine; Humans; Hyperhomocysteinemia; Microcirculation; Models, Cardiovascular; Neurodegenerative Diseases | 2005 |
Homocysteine: overview of biochemistry, molecular biology, and role in disease processes.
Topics: Animals; Disease Progression; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Oxidation-Reduction | 2005 |
Dietary determinants of plasma homocysteine concentrations.
Topics: Dietary Supplements; Feeding Behavior; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2005 |
Genetic determinants of plasma total homocysteine.
Topics: Cardiovascular Diseases; Genetic Markers; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors | 2005 |
Effect of drugs on homocysteine concentrations.
Topics: Anti-Inflammatory Agents; Anticonvulsants; Diuretics; Estrogens; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents | 2005 |
Homocysteine and endothelial function in human studies.
Topics: Blood Flow Velocity; Endothelium, Vascular; Folic Acid; Hematinics; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Vascular Diseases; Vasodilation | 2005 |
Mechanisms of the atherogenic effects of elevated homocysteine in experimental models.
Topics: Animals; Arteriosclerosis; Disease Models, Animal; Endothelium, Vascular; Homocysteine; Hyperhomocysteinemia; Methionine; Mice; Nitric Oxide; Oxidative Stress; Risk Factors | 2005 |
Homocysteine and folic acid: implications for pregnancy.
Topics: Canada; Female; Folic Acid; Food, Fortified; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; International Cooperation; National Health Programs; Neural Tube Defects; Pre-Eclampsia; Pregnancy; United States | 2005 |
Homocysteine and cognitive function.
Topics: Cognition; Cognition Disorders; Dementia; Dietary Supplements; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2005 |
Homocysteine-lowering trials for prevention of heart disease and stroke.
Topics: Biomarkers; Clinical Trials as Topic; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Treatment Outcome; Vitamin B Complex | 2005 |
Mechanisms of homocysteine-induced atherothrombosis.
Topics: Animals; Apolipoproteins E; Apoptosis; Arginine; Atherosclerosis; Coronary Thrombosis; Cysteine; Disease Models, Animal; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methionine; Mice; Models, Biological; Nitric Oxide; Oxidative Stress; Oxygen; Phenotype; Signal Transduction | 2005 |
Homocysteine and brain atrophy.
Topics: Alcoholism; Animals; Atrophy; Brain Diseases; Cognition Disorders; Homocysteine; Humans; Hyperhomocysteinemia | 2005 |
Homocysteine and folate metabolism in depression.
Topics: Animals; Depression; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Models, Biological; Neurotransmitter Agents; Vitamin B 12 Deficiency | 2005 |
Mitochondrial mechanism of oxidative stress and systemic hypertension in hyperhomocysteinemia.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Mitochondria; Oxidative Stress; Reactive Oxygen Species | 2005 |
The role of homocysteine in multisystem age-related problems: a systematic review.
Topics: Aging; Animals; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2005 |
Hyperhomocysteinemia and arteriosclerosis: historical perspectives.
Topics: Animals; Arteriosclerosis; History, 19th Century; History, 20th Century; History, 21st Century; Homocysteine; Humans; Hyperhomocysteinemia | 2005 |
Reduced adenosine receptor stimulation as a pathogenic factor in hyperhomocysteinemia.
Topics: Adenosine; Animals; Homocysteine; Humans; Hyperhomocysteinemia; Receptors, Purinergic P1 | 2005 |
Hyperhomocysteinemia and macromolecule modifications in uremic patients.
Topics: Animals; DNA; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Uremia | 2005 |
Hyperhomocysteinemia and response of methionine cycle intermediates to vitamin treatment in renal patients.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Methionine; Methylation; Vitamins | 2005 |
Homocysteine and coronary heart disease.
Topics: Adult; Child; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B Complex; Vitamins | 2002 |
[Homocysteine and diabetes].
Topics: Arteriosclerosis; Diabetes Complications; Diabetic Angiopathies; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2005 |
[Homocysteine--risk factor or risk indicator?].
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Child; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex | 2005 |
Homocysteine and thrombosis: from basic science to clinical evidence.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thrombosis | 2005 |
Hyperhomocysteinemia, malnutrition, and inflammation in ESRD patients.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Kidney Failure, Chronic; Malnutrition | 2006 |
Are B vitamins a risk factor for venous thromboembolism? Yes.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Recurrence; Risk Factors; Thromboembolism; Venous Thrombosis; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Deficiency | 2006 |
Are B vitamins a risk factor for VTE? Perhaps.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thromboembolism; Venous Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Deficiency | 2006 |
Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies.
Topics: Animals; Apoptosis; Atherosclerosis; Blood Coagulation; Cardiovascular Diseases; Epigenesis, Genetic; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Mutation; Nervous System Diseases; Oxidative Stress; Polymorphism, Genetic; Signal Transduction | 2006 |
ADMA and hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Homocysteine; Humans; Hyperhomocysteinemia; Nitric Oxide; Nitric Oxide Synthase Type III; Risk Factors; Superoxides; Vasodilation | 2005 |
Homocysteine: role and implications in atherosclerosis.
Topics: Atherosclerosis; Biomarkers; Disease Progression; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Risk Factors | 2006 |
The use of betaine in the treatment of elevated homocysteine.
Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation | 2006 |
Homocysteine and B vitamins.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Vitamin B Complex | 2005 |
Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: an overview.
Topics: Animals; DNA Methylation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Models, Biological; Vascular Diseases; Vitamin B Complex | 2006 |
Homocysteine, estrogen and cognitive decline.
Topics: Cognition; Estrogen Replacement Therapy; Estrogens; Female; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2006 |
The many facets of hyperhomocysteinemia: studies from the Framingham cohorts.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Massachusetts; Middle Aged; Risk Factors; Stroke; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease.
Topics: Adult; Aged; Aging; Bone Density; Cardiovascular Diseases; Cognition Disorders; Depression; Disease; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mortality; Norway; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors | 2006 |
Vitamins and minerals 4: overview of folate and the B vitamins.
Topics: Alzheimer Disease; Cardiovascular Diseases; Chemoprevention; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neoplasms; Primary Prevention; Risk Factors; Risk Reduction Behavior; Vitamin B 12; Vitamin B 6 | 2006 |
Hyperhomocysteinemia in movement disorders: Current evidence and hypotheses.
Topics: Adolescent; Adult; Animals; Case-Control Studies; Catechol O-Methyltransferase; Cystathionine beta-Synthase; Dopamine Agents; Dystonia; Homocysteine; Humans; Huntington Disease; Hyperhomocysteinemia; Levodopa; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Movement Disorders; Parkinson Disease; Prospective Studies | 2006 |
Homocysteine lowering with folic acid and vitamin B supplements: effects on cardiovascular disease in older adults.
Topics: Adult; Aging; Animals; Cardiovascular Diseases; Clinical Trials as Topic; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex; Vitamin B Deficiency | 2006 |
Is plasma homocysteine a modifiable risk factor for stroke?
Topics: Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Thrombosis; Vitamins | 2006 |
Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum.
Topics: Animals; Betaine; Endoplasmic Reticulum; Gastrointestinal Agents; Gene Expression Profiling; Glutathione; Homocysteine; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Mice; Mitochondria, Liver; Oxidative Stress; Rats; Sterol Regulatory Element Binding Proteins; Tumor Necrosis Factor-alpha | 2006 |
Hyperhomocysteinemia and venous thromboembolism.
Topics: Case-Control Studies; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Prospective Studies; Recurrence; Risk Factors; Thromboembolism; Thrombophilia; Venous Thrombosis; Vitamins | 2006 |
Synergy of genes and nutrients: the case of homocysteine.
Topics: Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Mood Disorders; Neoplasms; Public Health; Selection, Genetic; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Homocysteine and large arteries.
Topics: Arteries; Cardiovascular Diseases; Endothelium, Vascular; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Vascular Resistance | 2007 |
Biochemistry of homocysteine in health and diseases.
Topics: Animals; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Chemical; Oxidative Stress; Smoking; Thrombosis; Vitamin B 12; Vitamin B 6 | 2006 |
Homocysteine as a risk factor for cardiovascular disease: should we (still) worry about?
Topics: Biomarkers; Cardiovascular Diseases; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Randomized Controlled Trials as Topic; Risk Factors; Uncertainty; Vitamin B Complex | 2006 |
Hyperhomocysteinaemia: a critical review of old and new aspects.
Topics: Age Factors; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors; Sex Factors | 2007 |
Mechanisms of homocysteine toxicity in humans.
Topics: Animals; Aryldialkylphosphatase; Hemostasis; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Inflammation; Lipoproteins, HDL; Lipoproteins, LDL; Protein-Lysine 6-Oxidase; Proteins | 2007 |
[Hyperhomocysteinemia in pediatric age and nutritional aspects of folates: an early cardiovascular risk factor].
Topics: Atherosclerosis; Cardiovascular Diseases; Drug Therapy, Combination; Endothelium; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Homocysteine and Parkinson's disease: a dangerous liaison?
Topics: Brain; Brain Diseases, Metabolic; Causality; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Nerve Degeneration; Parkinson Disease | 2007 |
Vascular and cellular stress in inflammatory bowel disease: revisiting the role of homocysteine.
Topics: Animals; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Oxidative Stress; Risk Factors; Thromboembolism; Vitamin B 12 Deficiency | 2007 |
Hyperhomocysteinemia and venous thrombosis.
Topics: Female; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Pregnancy Complications, Hematologic; Prospective Studies; Retrospective Studies; Venous Thrombosis | 2007 |
[Risk factors for cardiovascular diseases: what is the role for homocysteine?].
Topics: Cardiovascular Diseases; Folic Acid; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
[Steatosis, chronic hepatitis virus C infection and homocysteine].
Topics: Adult; Animals; Antiviral Agents; Child; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Resistance, Viral; Fatty Liver; Fatty Liver, Alcoholic; Female; Hepacivirus; Hepatitis C, Chronic; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Insulin Resistance; Interferons; Liver; Liver Cirrhosis; Male; Mice; Mice, Transgenic; Multivariate Analysis; Mutation; Risk Factors | 2007 |
The homocysteine hypothesis of depression.
Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Child; Comorbidity; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mutation; Neurotransmitter Agents; Stroke; Vitamin B 12; Vitamin B 6 | 2007 |
Hyperhomocysteinemia and thrombosis: an overview.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Thromboembolism | 2007 |
Homocysteine in cardiovascular disease: a culprit or an innocent bystander?
Topics: Cardiovascular Diseases; Confounding Factors, Epidemiologic; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2007 |
[Nutritional medicine 2007].
Topics: Cardiovascular Diseases; Diet; Evidence-Based Medicine; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Practice Guidelines as Topic; Primary Prevention; Risk Assessment; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine lowering and cardiovascular disease risk: lost in translation.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Risk Factors; Survival Rate; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine and cardiovascular disease: a review of the evidence.
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Risk Assessment; Risk Factors; Treatment Outcome; Up-Regulation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
[Review of the role of hyperhomocysteinemia and B-vitamin deficiency in neurological and psychiatric disorders--current evidence and preliminary recommendations].
Topics: Aged; Central Nervous System; Child; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mental Disorders; Nervous System Diseases; Parkinson Disease; Risk Factors; Vitamin B 12; Vitamin B Deficiency | 2007 |
Vascular oxidant stress and inflammation in hyperhomocysteinemia.
Topics: Animals; Atherosclerosis; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Models, Biological; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2007 |
Homocysteine and glutathione peroxidase-1.
Topics: Animals; Atherosclerosis; Biological Availability; Endothelium, Vascular; Evidence-Based Medicine; Glutathione Peroxidase; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Muscle, Smooth, Vascular; Nitric Oxide; Thrombosis | 2007 |
Homocysteine and cerebral stroke in developing countries.
Topics: Developing Countries; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Nutritional Status; Stroke; Vitamin B 12 | 2007 |
[Homocysteine metabolism].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Cardiovascular Diseases; Deuterium; Gas Chromatography-Mass Spectrometry; Gout; Homocysteine; Humans; Hyperhomocysteinemia; Isotope Labeling; Methionine; Oxidation-Reduction; Risk Factors; Serum Albumin; Vitamin B 12 | 2007 |
Defects in homocysteine metabolism: diversity among hyperhomocyst(e)inemias.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Models, Animal | 2007 |
Homocysteine levels and peripheral arterial occlusive disease: a prospective cohort study and review of the literature.
Topics: Adult; Aged; Ankle; Arterial Occlusive Diseases; Blood Pressure; Brachial Artery; Cohort Studies; Cross-Sectional Studies; Diabetes Complications; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kuwait; Logistic Models; Male; Middle Aged; Odds Ratio; Peripheral Vascular Diseases; Prevalence; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Sex Factors | 2007 |
Homocysteine as a biomarker for cognitive dysfunction in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Cognition Disorders; Diagnosis, Differential; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Predictive Value of Tests; Vitamin B Complex | 2007 |
[Homocysteine and rheumatic disease].
Topics: Arthritis, Rheumatoid; Behcet Syndrome; Cardiovascular Diseases; Case-Control Studies; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Male; Meta-Analysis as Topic; Prospective Studies; Rheumatic Diseases; Risk Factors; Scleroderma, Systemic | 2007 |
Homocysteine toxicity in connective tissue: theories, old and new.
Topics: Animals; Aryldialkylphosphatase; Ascorbic Acid; Autoimmune Diseases; Collagen; Connective Tissue Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Sulfhydryl Compounds | 2008 |
Mitochondrial MMP activation, dysfunction and arrhythmogenesis in hyperhomocysteinemia.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Enzyme Activation; Extracellular Matrix; Heart Failure; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Matrix Metalloproteinases; Mitochondria, Heart; Myocytes, Cardiac; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2008 |
Mechanisms of thrombosis in hyperhomocysteinemia.
Topics: Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Thrombosis | 1998 |
Should all elderly people receive folate supplements?
Topics: Aged; Aging; Coronary Disease; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Nutritional Requirements; Nutritional Status | 1998 |
High plasma homocysteine: a risk factor for vascular disease in the elderly.
Topics: Aged; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vascular Diseases | 1998 |
Novel risk factors for vascular disease: the homocysteine hypothesis of cardiovascular disease.
Topics: Cardiovascular Diseases; Endothelium, Vascular; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Risk Factors | 1998 |
Plasma homocysteine and coronary heart disease: systematic review of published epidemiological studies.
Topics: Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 1998 |
Homocysteine and vascular disease: nature or nurture?
Topics: Cardiovascular Diseases; Diet; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 1998 |
Pathogenesis of vascular disease in hyperhomocysteinaemia.
Topics: Arteriosclerosis; Endothelium, Vascular; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Muscle, Smooth, Vascular; Risk Factors; Thrombosis | 1998 |
Can dietary supplements with folic acid or vitamin B6 reduce cardiovascular risk? Design of clinical trials to test the homocysteine hypothesis of vascular disease.
Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine; Randomized Controlled Trials as Topic; Research Design; Vitamin B 12 | 1998 |
Hyperhomocysteinemia, atherosclerosis and thrombosis.
Topics: Adult; Aged; Animals; Arteriosclerosis; Avitaminosis; Case-Control Studies; Clinical Trials as Topic; Cohort Studies; Cross-Sectional Studies; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle, Smooth, Vascular; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Primates; Prospective Studies; Pyridoxine; Risk Factors; Smoking; Tamoxifen; Thrombophilia; Thrombosis; Vitamin B 12 | 1999 |
Homocysteine: an emerging age-related cardiovascular risk factor.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Menopause; Methionine; Middle Aged; Prevalence; Primary Health Care; Risk Factors | 1999 |
[Hyperhomocysteinemia as a risk factor for venous thrombosis].
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Venous Thrombosis; Vitamin B 12 | 1999 |
Homocysteine and arterial occlusive disease: a concise review.
Topics: Arterial Occlusive Diseases; Biomarkers; Diet; Homocysteine; Humans; Hyperhomocysteinemia; Reference Values; Risk Factors | 1999 |
Homocysteine metabolism.
Topics: Animals; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nutritional Physiological Phenomena; Oxidoreductases Acting on CH-NH Group Donors | 1999 |
Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review.
Topics: Abortion, Habitual; Abortion, Spontaneous; Abruptio Placentae; Female; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Infarction; Odds Ratio; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors | 1999 |
Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence.
Topics: Arteriosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 1999 |
Potential new cardiovascular risk factors: left ventricular hypertrophy, homocysteine, lipoprotein(a), triglycerides, oxidative stress, and fibrinogen.
Topics: Cardiovascular Diseases; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Hypertriglyceridemia; Hypertrophy, Left Ventricular; Lipoprotein(a); Oxidative Stress; Risk Factors; Triglycerides | 1999 |
Homocysteine and risk for atherothrombotic events.
Topics: Arteriosclerosis; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thrombosis | 1999 |
[Hyperhomocysteinemia: a risk factor for arterial and venous thrombosis].
Topics: Arteriosclerosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine; Risk Factors; Thromboembolism; Vitamin B 12 | 1999 |
Homocyst(e)ine, atherosclerosis, and thrombosis.
Topics: Adult; Aged; Arteriosclerosis; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Hyperhomocysteinemia; Male; Middle Aged; Thrombosis | 1999 |
Homocysteine and risk of stroke.
Topics: Arteriosclerosis; Carotid Stenosis; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Prevalence; Risk Factors; Stroke | 1999 |
Homocysteine and endothelial function.
Topics: Aged; Cardiovascular Diseases; Endothelium, Vascular; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regional Blood Flow; Risk Factors; Vasodilation | 1999 |
[Hyperhomocysteinemia, a risk factor for atherosclerosis: causes and effects].
Topics: Age Factors; Arterial Occlusive Diseases; Arteriosclerosis; Cerebrovascular Disorders; Coronary Disease; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Metabolism; Lipoproteins; Male; Meta-Analysis as Topic; Methionine; Middle Aged; Peripheral Vascular Diseases; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors | 1999 |
Homocysteine and coronary heart disease: a review of the current evidence.
Topics: Animals; Case-Control Studies; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Prospective Studies; Risk Assessment; Sensitivity and Specificity | 1999 |
Homocysteine and risk of cardiovascular disease.
Topics: Arteriosclerosis; Biomarkers; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thrombosis | 2000 |
Novel risk factors and markers for coronary disease.
Topics: Biomarkers; C-Reactive Protein; Coronary Disease; Fibrinogen; Fibrinolysis; Homocysteine; Humans; Hyperhomocysteinemia; Lipoprotein(a); Risk Factors; Thrombophilia; Vasculitis | 2000 |
Moderate hyperhomocysteinemia and cardiovascular disease.
Topics: Animals; Arterial Occlusive Diseases; Cardiovascular Diseases; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thrombosis | 2000 |
Emerging risk factors associated with cardiovascular diseases.
Topics: Adult; Aged; Blood Coagulation Factors; Cardiovascular Diseases; Chlamydia Infections; Chlamydophila pneumoniae; Homocysteine; Humans; Hyperhomocysteinemia; Lipoprotein(a); Middle Aged; Risk Factors | 1999 |
Mechanisms of homocysteine toxicity on connective tissues: implications for the morbidity of aging.
Topics: Aging; Animals; Chronic Disease; Connective Tissue; Epidermal Growth Factor; Homocysteine; Humans; Hyperhomocysteinemia | 2000 |
Hyperhomocysteinaemia as a cardiovascular risk factor: an update.
Topics: Adult; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2000 |
Hyperhomocysteinemia in organ transplantation.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Organ Transplantation; Polymorphism, Genetic; Pyridoxine; Risk Factors; Vitamin B 12 | 2000 |
[Hyperhomocysteinemia: atherothrombosis and neurotoxicity].
Topics: Brain Ischemia; Homocysteine; Humans; Hyperhomocysteinemia; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Risk Factors; Thrombosis; Vascular Diseases | 1999 |
Homocysteine and critical illness.
Topics: Critical Illness; Homocysteine; Humans; Hyperhomocysteinemia | 2000 |
Hyperhomocysteinemia as a risk factor for cardiovascular diseases. The association of hyperhomocysteinemia with diabetes mellitus and renal transplant recipients.
Topics: Cardiovascular Diseases; Diabetes Complications; Diabetic Nephropathies; Diabetic Retinopathy; Endothelium, Vascular; Heart Transplantation; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Risk Factors | 1999 |
Hyperhomocysteinaemia.
Topics: Animals; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Pregnancy; Risk Factors; Thrombophilia; Thrombosis; Vascular Diseases; Vitamin B Complex | 1999 |
Homocysteine as a cardiovascular risk factor.
Topics: Cardiovascular Diseases; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Risk Factors; Vitamins | 2000 |
Clinical relevance of hyperhomocysteinaemia in atherothrombotic disease.
Topics: Arteriosclerosis; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thrombosis | 2000 |
Homocysteine and its disulfide derivatives: a suggested consensus terminology.
Topics: Disulfides; Homocysteine; Humans; Hyperhomocysteinemia; Terminology as Topic | 2000 |
Homocysteine and ischaemic heart disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Cohort Studies; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Ischemia; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Retrospective Studies | 1999 |
Homocysteine, folate enzymes and neural tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Pregnancy Complications; Vitamin B 12 | 1999 |
Homocysteine, platelet function and thrombosis.
Topics: Arterial Occlusive Diseases; Blood Coagulation Factors; Blood Platelets; Comorbidity; Endothelium, Vascular; Fibrinolysis; Free Radicals; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Nitric Oxide; Oxidative Stress; Thrombin; Thrombomodulin; Thrombophilia; Thromboxane A2 | 1999 |
[Hyperhomocysteinemia--a risk factor or vascular disease?].
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vascular Diseases | 1999 |
[Dialysis patients and cyclosporine-treated graft recipients: two sectors with high homocysteine levels].
Topics: Cyclosporine; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Renal Dialysis; Transplantation Immunology | 1999 |
Homocysteine and cardiovascular disease: cause or effect?
Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases | 2000 |
The controversy over homocysteine and cardiovascular risk.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Kidney Diseases; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Prospective Studies; Risk Factors; Vitamin B Complex | 2000 |
Preventive health care, 2000 update: screening and management of hyperhomocysteinemia for the prevention of coronary artery disease events. The Canadian Task Force on Preventive Health Care.
Topics: Aged; Arteriosclerosis; Canada; Coronary Disease; Dietary Supplements; Disease Susceptibility; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Methionine; Preventive Medicine; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12 | 2000 |
Hyperhomocysteinemia and thrombosis.
Topics: Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Male; Pregnancy; Risk Factors; Thrombosis | 2000 |
Nutritional aspects and possible pathological mechanisms of hyperhomocysteinaemia: an independent risk factor for vascular disease.
Topics: Arteriosclerosis; Cardiovascular Diseases; Diet; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Nutritional Status; Risk Factors; Vitamin B Complex | 2000 |
Homocysteine and coronary risk.
Topics: Age Factors; Clinical Trials as Topic; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Risk Factors; Sex Factors | 1999 |
Homocysteine: an emergent cardiovascular risk factor?
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2000 |
Consequences of homocysteine export and oxidation in the vascular system.
Topics: Arteriosclerosis; Blood Cells; Cardiovascular System; Disulfides; Endothelium, Vascular; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Liver; Oxidation-Reduction; Thrombophilia | 2000 |
Assay methods for the measurement of total homocyst(e)ine in plasma.
Topics: Bridged Bicyclo Compounds; Chromatography, Gas; Chromatography, High Pressure Liquid; Eating; Electrochemistry; Electrophoresis, Capillary; Fluorescent Dyes; Fluorobenzenes; Fluorometry; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Posture; Reproducibility of Results; Specimen Handling; Spectrometry, Mass, Electrospray Ionization | 2000 |
Homocysteine, coagulation, platelet function, and thrombosis.
Topics: Adolescent; Adult; Arteriosclerosis; Blood Coagulation; Cardiovascular Diseases; Cellular Senescence; Child; Endothelium, Vascular; Female; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Lipoproteins, LDL; Male; Methyltransferases; Oxidation-Reduction; Platelet Activation; Reactive Oxygen Species; Renal Insufficiency; Risk Factors; S-Adenosylhomocysteine; Thrombophilia; Thromboxane B2; Vitamin K | 2000 |
Genetic modulation of homocysteinemia.
Topics: Amino Acid Substitution; Cardiovascular Diseases; Cystathionine beta-Synthase; Cysteine; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methyltransferases; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Sulfur; Tetrahydrofolates | 2000 |
Biological and environmental determinants of plasma homocysteine.
Topics: Adult; Aged; Aging; Alcohol Drinking; Child; Cystathionine beta-Synthase; Diagnosis-Related Groups; Dietary Proteins; Endocrine System Diseases; Female; Folic Acid Antagonists; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Inflammation; Intestinal Diseases; Life Style; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Niacin; Nitrous Oxide; Norway; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Renal Insufficiency; Smoking; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Homocysteine and renal disease.
Topics: Adult; Arteriosclerosis; Cardiovascular Diseases; Case-Control Studies; Child; Endothelium, Vascular; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Life Tables; Male; Methionine; Peritoneal Dialysis; Prospective Studies; Pyridoxine; Renal Dialysis; Survival Analysis; Thrombophilia; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Vitamin supplements and cardiovascular risk: review of the randomized trials of homocysteine-lowering vitamin supplements.
Topics: Adult; Aged; Cardiovascular Diseases; Clinical Trials as Topic; Diet; Double-Blind Method; Drug Synergism; Europe; Female; Folic Acid; Forecasting; Genetic Variation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; North America; Prospective Studies; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Treatment Outcome; Vitamin B 12 | 2000 |
Vascular complications of severe hyperhomocysteinemia in patients with homocystinuria due to cystathionine beta-synthase deficiency: effects of homocysteine-lowering therapy.
Topics: Adolescent; Adult; Aged; Australia; Child; Child, Preschool; Cohort Studies; Cystine; Drug Resistance; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Ireland; Male; Methionine; Middle Aged; Netherlands; Pyridoxine; Risk; Risk Factors; Thrombophilia; Vascular Diseases; Vitamin B 12 | 2000 |
Homocysteine and neurologic disease.
Topics: Brain Diseases; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Pyridoxine; Vascular Diseases; Vitamin B 12 | 2000 |
Therapeutic potential of total homocysteine-lowering drugs on cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Renal Dialysis; Risk Factors; Vitamin B 12 | 2000 |
Folate and homocysteine.
Topics: Blood Vessels; Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Polymorphism, Genetic; Risk Factors; Vitamin B Complex | 2000 |
[Homocysteine and pregnancy].
Topics: Biomarkers; Female; Homocysteine; Humans; Hyperhomocysteinemia; Pregnancy; Pregnancy Complications; Risk Factors; Thrombosis | 2000 |
Hyperhomocyst(e)inemia, related vitamins and dementias.
Topics: Aged; Aging; Dementia; Dietary Supplements; Folic Acid Deficiency; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B 12 Deficiency | 2000 |
Antioxidants and vitamins to reduce cardiovascular disease.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Carotenoids; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Vitamins | 2000 |
Diagnosis and treatment of hyperhomocysteinemia.
Topics: Biomarkers; Homocysteine; Humans; Hyperhomocysteinemia; Vitamins | 2001 |
Homocysteine and transmethylations in uremia.
Topics: Acylation; Amino Acids; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Nitroso Compounds; Oxidation-Reduction; Proteins; Uremia | 2001 |
Homocysteine metabolism in renal failure.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases | 2001 |
Homocyst(e)ine, oxidative stress, and endothelium function in uremic patients.
Topics: Animals; Arteriosclerosis; Endothelium, Vascular; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Uremia; Vasodilation | 2001 |
Recent insights into the molecular genetics of the homocysteine metabolism.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Anemia, Megaloblastic; Animals; Carrier Proteins; Folate Receptor 1; Folate Receptors, GPI-Anchored; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Molecular Biology; Oxidoreductases; Point Mutation; Polymorphism, Genetic; Receptors, Cell Surface; Renal Replacement Therapy; Syndrome | 2001 |
Getting to the heart of homocysteine testing.
Topics: Cardiovascular Diseases; Chromatography, High Pressure Liquid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Mass Screening; Reference Values; Reproducibility of Results; Risk Factors; Specimen Handling | 2000 |
Homocysteine: a new cardiac risk factor?
Topics: Coronary Artery Disease; Coronary Disease; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Risk Factors | 2001 |
Hyperhomocysteinaemia and atherothrombosis.
Topics: Causality; Comorbidity; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Thrombosis | 2000 |
[Homocysteine, endothelial dysfunction and cardiovascular risk: pathomechanisms and therapeutic options].
Topics: Adult; Aged; Cardiovascular Diseases; Clinical Trials as Topic; Drug Therapy, Combination; Endothelium, Vascular; Female; Fibrinolysis; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Time Factors; Vitamin B Complex | 2001 |
[Homocysteine and cardiovascular risk].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Arteriosclerosis; Clinical Trials as Topic; Coronary Artery Disease; Disease Models, Animal; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Vitamin B 12 | 2001 |
Homocysteine: a sulph'rous fire.
Topics: Animals; Arteriosclerosis; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Inflammation; Male; Vascular Diseases | 2001 |
[Homocysteine--new risk factor for progression of atherosclerosis and its complications].
Topics: Arteriosclerosis; Disease Progression; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Risk Factors | 2001 |
Impaired homocysteine metabolism and atherothrombotic disease.
Topics: Age Factors; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Models, Chemical; Risk Factors; S-Adenosylmethionine; Sex Factors | 2001 |
Hyperhomocysteinemia in end-stage renal failure.
Topics: Arteriosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Risk Factors | 2000 |
[From gene to disease; from homocysteine to hyperhomocysteinemia].
Topics: Cystathionine beta-Synthase; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Hyperhomocysteinemia; Methionine; Mutation; Risk Factors; Vascular Diseases | 2001 |
[Chronic complication of diabetes and homocysteine].
Topics: Cardiovascular Diseases; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2000 |
Aetiology and treatment of hyperhomocysteinaemia causing ischaemic stroke.
Topics: Anemia, Pernicious; Brain Ischemia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypothyroidism; Kidney Failure, Chronic; Male; Neoplasms; Risk Assessment; Risk Factors; Thrombosis | 2001 |
[Role of polymorphic variants of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene in the pathogenesis of cardiovascular diseases].
Topics: Alleles; Animals; Cardiovascular Diseases; Genetic Variation; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Racial Groups | 2001 |
Homocysteine and cardiovascular risk in patients with diabetes mellitus.
Topics: Coronary Disease; Diabetes Complications; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Metformin; Risk Factors; Vitamin B Complex | 2001 |
Roles of homocysteine in cell metabolism: old and new functions.
Topics: Cardiovascular Diseases; Cell Physiological Phenomena; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nervous System Malformations; Pregnancy; Pregnancy Complications; RNA, Transfer, Amino Acyl; S-Adenosylmethionine | 2001 |
Does lowering plasma homocysteine reduce vascular disease risk?
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine; Risk Factors; Vascular Diseases | 2001 |
[Homocysteine--a risk factor for atherosclerosis].
Topics: Antioxidants; Arteriosclerosis; Disease Progression; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Risk Factors; Thrombosis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2001 |
[Homocysteine. The cardiovascular risk factor of the next millennium?].
Topics: Animals; Arteriosclerosis; Cardiovascular Diseases; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Risk Factors; Thromboembolism | 2001 |
Association of endothelial dysfunction with sulfur amino acid metabolism in chronic renal failure.
Topics: Animals; Arteriosclerosis; Chronic Disease; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Dialysis; Stress, Mechanical; Vascular Diseases | 2001 |
Homocysteine, folate, and cardiovascular disease.
Topics: Antioxidants; Cardiovascular Diseases; Europe; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Primary Prevention; Risk Factors; Vegetables | 2001 |
Homocysteine-lowering treatment: an overview.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Vitamin B Deficiency; Vitamins | 2001 |
The importance of hyperhomocysteinemia as a risk factor for diseases: an overview.
Topics: Diet, Vegetarian; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Methylation; Models, Biological; Models, Chemical; Pregnancy; Risk Factors; Vascular Diseases; Vitamin B 12 Deficiency | 2001 |
Vascular dysfunction in hyperhomocyst(e)inemia. Implications for atherothrombotic disease.
Topics: Endothelium, Vascular; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Models, Biological; Models, Chemical; Oxidative Stress; Vascular Diseases; Venous Thrombosis | 2001 |
Hyperhomocysteinemia in chronic renal failure patients: relation to nutritional status and cardiovascular disease.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Models, Chemical; Mutation; Renal Insufficiency; Serum Albumin | 2001 |
Hyperhomocysteinaemia and human reproduction.
Topics: Abortion, Spontaneous; Chromosome Aberrations; Congenital Abnormalities; Family Health; Female; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Mutation; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors | 2001 |
MTHFR gene polymorphism, homocysteine and cardiovascular disease.
Topics: Apolipoproteins E; Arteriosclerosis; Cardiovascular Diseases; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prevalence; Risk Factors | 2001 |
Folate, homocysteine, endothelial function and cardiovascular disease. What is the link?
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Endothelium, Vascular; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Nitric Oxide; Oxidoreductases Acting on CH-NH Group Donors; Vitamins | 2001 |
Cardiovascular risk in the Asia-Pacific region from a nutrition and metabolic point of view: vitamin deficiencies.
Topics: Aged; Antioxidants; Asia; Avitaminosis; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pacific Islands; Risk Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Therapy of hyperhomocysteinemia in end-stage renal disease patients.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Replacement Therapy; Vitamin B 12; Vitamin B 6 | 2001 |
Assessment of homocysteine as a cardiovascular risk factor in clinical practice.
Topics: Biomarkers; Blood Chemical Analysis; Cardiovascular Diseases; Clinical Trials as Topic; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Mutation; Risk Factors; Vitamin B 12 | 2001 |
Homocysteine in myointimal hyperplasia.
Topics: Animals; Arterial Occlusive Diseases; Cell Division; Coronary Restenosis; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Hyperplasia; Muscle, Smooth, Vascular; Recurrence; Tunica Intima | 2002 |
Non-traditional risk factors for atherosclerosis.
Topics: Arteriosclerosis; Biomarkers; C-Reactive Protein; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Lipoprotein(a); Risk Factors | 2001 |
Homocysteine and atherothrombosis.
Topics: Arteriosclerosis; Diet; Homocysteine; Humans; Hyperhomocysteinemia; Myocardial Ischemia; Risk Factors; Stroke; Thrombosis | 2001 |
Hyperhomocysteinemia and thrombosis.
Topics: Animals; Arteriosclerosis; Case-Control Studies; Cross-Sectional Studies; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thrombosis; Venous Thrombosis | 2001 |
Emergent cardiovascular risk factor: homocysteine.
Topics: Blood Chemical Analysis; Cardiovascular Diseases; Folic Acid; Health Education; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 6 | 2002 |
Drugs affecting homocysteine metabolism: impact on cardiovascular risk.
Topics: Anticonvulsants; Betaine; Cardiovascular Diseases; Clinical Trials as Topic; Gonadal Steroid Hormones; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Lipotropic Agents; Risk Factors | 2002 |
Homocysteine.
Topics: Arteriosclerosis; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Diseases | 2002 |
Plasma homocysteine: a new risk factor for Alzheimer's disease?
Topics: Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2002 |
Homocysteine and cardiovascular disease: current evidence and future prospects.
Topics: Blood Coagulation Disorders; Cardiovascular Diseases; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Muscle, Smooth, Vascular; Risk Factors | 2002 |
Hyperhomocyst(e)inemia as a risk factor after renal transplantation.
Topics: Cardiovascular Diseases; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Risk Factors | 2001 |
Postmethionine-load homocysteine determination for the diagnosis hyperhomocysteinaemia and efficacy of homocysteine lowering treatment regimens.
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome | 2002 |
Hormones and homocysteine.
Topics: Diabetic Angiopathies; Homocysteine; Hormones; Humans; Hyperhomocysteinemia; Hyperlipidemias; Methionine; Vascular Diseases | 2002 |
Hyperhomocysteinemia is a risk factor for cancer and a new potential tumor marker.
Topics: Biomarkers, Tumor; Homocysteine; Humans; Hyperhomocysteinemia; Neoplasms; Oxidative Stress; Risk Factors | 2002 |
194 trial(s) available for homocysteine and Hyperhomocysteinemia
| Article | Year |
|---|---|
Effects of individualized administration of folic acid on prothrombotic state and vascular endothelial function with H-type hypertension: A double-blinded, randomized clinical cohort study.
Topics: Amlodipine; Cohort Studies; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Precision Medicine; Vascular Endothelial Growth Factor A | 2022 |
Adolescent Afghan Refugees Display a High Prevalence of Hyperhomocysteinemia and Associated Micronutrients Deficiencies Indicating an Enhanced Risk of Cardiovascular Disease in Later Life.
Topics: Adolescent; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Micronutrients; Prevalence; Refugees; Vitamin B 12 | 2022 |
Pirfenidone alleviates vascular intima injury caused by hyperhomocysteinemia.
Topics: Animals; Antioxidants; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Hyperplasia; Lipids; Malondialdehyde; Methionine; Oxidants; Pyridones; Rabbits; Reactive Oxygen Species; Superoxide Dismutase; Tunica Intima | 2022 |
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial.
Topics: Adolescent; Adult; Aged; Betaine; Dietary Supplements; Double-Blind Method; East Asian People; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 12; Vitamin B Complex; Young Adult | 2023 |
Combined use of amlodipine and folic acid are significantly more efficacious than amlodipine alone in lowering plasma homocysteine and blood pressure among hypertensive patients with hyperhomocysteinemia and intolerance to ACEI: A multicenter, randomized,
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Stroke; Treatment Outcome | 2023 |
A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients.
Topics: Aged; Aged, 80 and over; Cognition; Cognitive Dysfunction; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2020 |
Homocysteine Level Predicts Response to Dual Antiplatelet in Women With Minor Stroke or Transient Ischemic Attack: Subanalysis of the CHANCE Trial.
Topics: Aged; Aspirin; Biomarkers; China; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Risk Assessment; Risk Factors; Sex Factors; Stroke; Time Factors; Treatment Outcome | 2020 |
Effects of vitamin B12, folate, and entacapone on homocysteine levels in levodopa-treated Parkinson's disease patients: A randomized controlled study.
Topics: Aged; Antiparkinson Agents; Catechols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Research Design; Vitamin B 12 | 2021 |
Association between malnutrition and hyperhomocysteine in Alzheimer's disease patients and diet intervention of betaine.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Betaine; Case-Control Studies; Dementia; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Memory; Nerve Tissue Proteins; Risk Factors | 2017 |
Muscular contraction frequency does not affect plasma homocysteine concentration in response to energy expenditure- and intensity-matched acute exercise in sedentary males.
Topics: Adult; Anthropometry; Cross-Over Studies; Diet; Energy Metabolism; Exercise; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Muscle Contraction; Nutritional Status; Physical Endurance; Sedentary Behavior; Vitamin B 12; Vitamin B 6; Young Adult | 2018 |
Nitration-mediated deficiency of cystathionine β-synthase activity accelerates the progression of hyperhomocysteinemia.
Topics: Adult; Aged; Aged, 80 and over; Animals; Cystathionine beta-Synthase; Disease Models, Animal; Disease Progression; Female; Free Radical Scavengers; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metalloporphyrins; Middle Aged; Mutation; Nitro Compounds; Nitrosative Stress; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tyrosine | 2017 |
B-Vitamin Therapy for Kidney Transplant Recipients Lowers Homocysteine and Improves Selective Cognitive Outcomes in the Randomized FAVORIT Ancillary Cognitive Trial.
Topics: Cognition; Cognition Disorders; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; North America; Postoperative Complications; Treatment Outcome; Vitamin B Complex | 2017 |
Homocysteine as a non-classical risk factor for atherosclerosis in relation to pharmacotherapy of type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Risk Factors; Waist Circumference | 2017 |
Rehydration during exercise prevents the increase of homocysteine concentrations.
Topics: Adult; Creatine; Creatinine; Cross-Over Studies; Drinking Water; Exercise; Fluid Therapy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Isotonic Solutions; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Young Adult | 2019 |
Effect of long-term low-dose folic acid supplementation on degree of total homocysteine-lowering: major effect modifiers.
Topics: Aged; China; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Genotype; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Smoking; Stroke | 2018 |
Hyperhomocysteinaemia and the risk of recurrent venous thrombosis: results from the MEGA follow-up study.
Topics: Adolescent; Adult; Aged; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Recurrence; Risk Factors; Venous Thrombosis | 2019 |
Vitamin B12 and homocysteine status during pregnancy in the metformin in gestational diabetes trial: responses to maternal metformin compared with insulin treatment.
Topics: Adult; Biomarkers; Cohort Studies; Diabetes, Gestational; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Metformin; Nutritional Status; Postpartum Period; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnancy Trimester, Third; South Australia; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Homocysteine lowering by folate-rich diet or pharmacological supplementations in subjects with moderate hyperhomocysteinemia.
Topics: Adult; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Severity of Illness Index; Tetrahydrofolates; Vitamin B Complex | 2013 |
Daily milk intake improves vitamin B-12 status in young vegetarian Indians: an intervention trial.
Topics: Adult; Animals; Buffaloes; Diet, Fat-Restricted; Diet, Vegetarian; Female; Functional Food; Health Promotion; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Milk; Nutrition Policy; Nutritional Sciences; Nutritional Status; Patient Education as Topic; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Phytoestrogen α-Zearalanol attenuates homocysteine-induced apoptosis in human umbilical vein endothelial cells.
Topics: Animals; Apoptosis; Atherosclerosis; bcl-2-Associated X Protein; Caspase 9; Down-Regulation; Estrogens, Non-Steroidal; Female; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Rats; Zeranol | 2013 |
Predicting Hyperhomocysteinemia by Methylenetetrahydrofolate Reductase C677T Polymorphism in Chinese Patients With Hypertension.
Topics: Adult; Aged; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2015 |
B-vitamin levels and genetics of hyperhomocysteinemia are not associated with arterial stiffness.
Topics: Aged; Aged, 80 and over; Blood Pressure; Body Mass Index; Creatinine; Cross-Sectional Studies; Double-Blind Method; Female; Folic Acid; Genotyping Techniques; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Methylmalonic Acid; Multivariate Analysis; Pulse Wave Analysis; Risk Factors; Vascular Stiffness; Vitamin B 12; Vitamin B Complex | 2014 |
B vitamin supplementation improves cognitive function in the middle aged and elderly with hyperhomocysteinemia.
Topics: Aged; Aged, 80 and over; Aging; China; Cognitive Dysfunction; Dietary Supplements; Elder Nutritional Physiological Phenomena; Female; Folic Acid; Follow-Up Studies; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nursing Homes; Prevalence; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
Effect of folic acid supplementation on plasma homocysteine in obese children: a randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Body Mass Index; Child; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pediatric Obesity | 2014 |
Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Endpoint Determination; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Motor Activity; Netherlands; Osteoporotic Fractures; Risk Factors; Treatment Outcome; Vitamin B 12 | 2014 |
Effect of N-acetylcysteine administration on homocysteine level, oxidative damage to proteins, and levels of iron (Fe) and Fe-related proteins in lead-exposed workers.
Topics: Acetylcysteine; Adult; Air Pollutants, Occupational; Anemia, Iron-Deficiency; Antioxidants; Dietary Supplements; Haptoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Inhalation Exposure; Iron; Lead; Lead Poisoning; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Oxidative Stress; Poland; Protein Carbonylation; Protoporphyrins; Transferrin | 2016 |
Cyclic supplementation of 5-MTHF is effective for the correction of hyperhomocysteinemia.
Topics: Adult; Dietary Supplements; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prospective Studies; Tetrahydrofolates; Treatment Outcome | 2015 |
Different responses of the retinal and cutaneous microcirculation to transient dysmetabolic conditions.
Topics: Acetylcholine; Administration, Cutaneous; Adult; Dietary Fats; Germany; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Iontophoresis; Laser-Doppler Flowmetry; Light; Male; Methionine; Microcirculation; Microvessels; Photic Stimulation; Predictive Value of Tests; Regional Blood Flow; Reproducibility of Results; Retinal Vessels; Skin; Vasodilation; Vasodilator Agents; Young Adult | 2015 |
Acute hyperlipidemia but not hyperhomocysteinemia impairs reflex regulation of the cardiovascular system.
Topics: Adrenergic beta-Agonists; Adult; Baroreflex; Blood Pressure; Cardiovascular System; Dietary Fats; Germany; Heart Rate; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methionine; Sympathetic Nervous System; Time Factors; Vagus Nerve; Vasodilator Agents; Young Adult | 2015 |
Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial.
Topics: Adult; Bangladesh; Biomarkers; Cohort Studies; Creatine; Dietary Supplements; Double-Blind Method; Down-Regulation; Female; Folic Acid; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Intention to Treat Analysis; Male; Middle Aged; Patient Dropouts; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Oral N-acetylcysteine reduces plasma homocysteine concentrations regardless of lipid or smoking status.
Topics: Acetylcysteine; Administration, Oral; Adult; Antihypertensive Agents; Antioxidants; Biotransformation; Cholesterol; Cysteine; Double-Blind Method; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Leukocytes, Mononuclear; Male; Middle Aged; Smoking; Triglycerides | 2015 |
The C677T MTHFR genotypes influence the efficacy of B9 and B12 vitamins supplementation to lowering plasma total homocysteine in hemodialysis.
Topics: Adult; Biomarkers; Dietary Supplements; Down-Regulation; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Renal Dialysis; Time Factors; Treatment Outcome; Tunisia; Vitamin B 12; Vitamins | 2016 |
Effect of vitamin B12 and folic acid supplementation on biomarkers of endothelial function and inflammation among elderly individuals with hyperhomocysteinemia.
Topics: Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers; Dietary Supplements; Double-Blind Method; Drug Combinations; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Inflammation Mediators; Male; Netherlands; Time Factors; Treatment Outcome; Vitamin B 12 | 2016 |
Hyperhomocysteinaemia is an independent risk factor of abdominal aortic aneurysm in a Chinese Han population.
Topics: Aged; Aortic Aneurysm, Abdominal; Asian People; Case-Control Studies; China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors | 2016 |
Homocysteinemia control by cysteine in cerebral vascular patients after methionine loading test: evidences in physiological and pathological conditions in cerebro-vascular and multiple sclerosis patients.
Topics: Adult; Cerebrovascular Disorders; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Multiple Sclerosis; Serum Albumin, Human | 2016 |
Effect of Vitamin B12 supplementation on serum homocysteine in patients undergoing hemodialysis: A randomized controlled trial.
Topics: Aged; Biomarkers; Dietary Supplements; Female; Hematocrit; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2016 |
Homocysteine Levels in Parkinson's Disease: Is Entacapone Effective?
Topics: Adult; Aged; Aged, 80 and over; Catechol O-Methyltransferase; Catechols; Dopamine Agonists; Female; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Prospective Studies | 2016 |
Guanidinoacetic acid versus creatine for improved brain and muscle creatine levels: a superiority pilot trial in healthy men.
Topics: Adult; Biomarkers; Creatine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Follow-Up Studies; Frontal Lobe; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Spectroscopy; Male; Middle Cerebellar Peduncle; Neurons; Performance-Enhancing Substances; Pilot Projects; Quadriceps Muscle; Serbia; Up-Regulation; Young Adult | 2016 |
Rivastigmine versus placebo in hyperhomocysteinemic Parkinson's disease dementia patients.
Topics: Aged; Analysis of Variance; Dementia; Double-Blind Method; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Middle Aged; Neuroprotective Agents; Parkinson Disease; Phenylcarbamates; Prospective Studies; Rivastigmine; Severity of Illness Index | 2008 |
[Effect of low-dose folate treatment on plasma homocystyeine and chemokine levels in patients with hyperhomocysteinemia].
Topics: Aged; Chemokines; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Treatment Outcome | 2008 |
Comparative effects of atorvastatin and simvastatin on the plasma total homocysteine levels in women with polycystic ovary syndrome: a prospective randomized study.
Topics: Adult; Anticholesteremic Agents; Atorvastatin; Female; Heptanoic Acids; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Clearance Rate; Polycystic Ovary Syndrome; Pyrroles; Retrospective Studies; Simvastatin; Treatment Outcome | 2009 |
Methionine-loading rapidly impairs endothelial function, by mechanisms independent of endothelin-1: evidence for an association of fasting total homocysteine with plasma endothelin-1 levels.
Topics: Analysis of Variance; Antioxidants; Ascorbic Acid; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Fasting; Female; Forearm; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, LDL; Male; Methionine; Oxidative Stress; Regional Blood Flow; Vitamin E | 2008 |
A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Chi-Square Distribution; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Psychometrics; Risk Factors; Statistics, Nonparametric; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Dietary intervention with emphasis on folate intake reduces serum lipids but not plasma homocysteine levels in hyperlipidemic patients.
Topics: Adult; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Chi-Square Distribution; Diet; Diet Records; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Korea; Lipids; Male; Middle Aged; Vitamins | 2008 |
The effect of folic acid supplementation on carotid intima-media thickness in patients with cardiovascular risk: a randomized, placebo-controlled trial.
Topics: Aged; Carotid Artery Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; Risk Factors; Tunica Intima; Tunica Media; Ultrasonography; Vitamin B Complex | 2010 |
Effect of long-term homocysteine reduction with B vitamins on arterial wall inflammation assessed by fluorodeoxyglucose positron emission tomography: a randomised double-blind, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Aorta; Arteritis; Atherosclerosis; Brachial Artery; Carotid Arteries; Cross-Sectional Studies; Double-Blind Method; Drug Combinations; Female; Femoral Artery; Fluorodeoxyglucose F18; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Stroke; Time Factors; Treatment Outcome; Ultrasonography; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2009 |
Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trial.
Topics: Aged; Disability Evaluation; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2009 |
Mesna for the treatment of hyperhomocysteinemia in hemodialysis patients.
Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Mesna; Middle Aged; Pilot Projects; Renal Dialysis | 2009 |
Hyperhomocysteinemia in levodopa-treated patients with Parkinson's disease dementia.
Topics: Aged; Analysis of Variance; Antiparkinson Agents; Case-Control Studies; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Dementia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Logistic Models; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Parkinson Disease | 2009 |
Influence of folic acid on plasma homocysteine levels & arterial endothelial function in patients with unstable angina.
Topics: Acute Coronary Syndrome; Adult; Aged; Angina, Unstable; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vasodilation; Vitamin B 12; Vitamin B Complex | 2009 |
Efficacy of folate and vitamin B12 in lowering homocysteine concentrations in hemodialysis patients.
Topics: Administration, Oral; Adult; Aged; Biomarkers; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2009 |
Shear stress inhibits homocysteine-induced stromal cell-derived factor-1 expression in endothelial cells.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Cells, Cultured; Chemokine CXCL12; Dose-Response Relationship, Drug; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; Male; MAP Kinase Kinase 4; Middle Aged; Nitric Oxide Donors; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Risk Factors; RNA, Small Interfering; Sp1 Transcription Factor; Stress, Physiological; Transcription Factor AP-1 | 2009 |
Homocysteine lowering with folic acid supplements in children: effects on blood pressure.
Topics: Adolescent; Age Factors; Blood Pressure; Child; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2010 |
Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life.
Topics: Age Factors; Antidepressive Agents; Biomarkers; Citalopram; Depression; Double-Blind Method; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Medication Adherence; Middle Aged; Psychiatric Status Rating Scales; Research Design; Severity of Illness Index; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Western Australia | 2010 |
The activation of endothelin-1 pathway during methionine-induced homocysteinemia mediates endothelial dysfunction in hypertensive individuals.
Topics: Adult; Ascorbic Acid; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methionine; Oxidative Stress; Signal Transduction; Vasodilation; Vitamin E | 2010 |
Acute hyperhomocysteinemia impairs endothelium function in subjects with type 2 diabetes mellitus.
Topics: Aged; Blood Glucose; Blood Pressure; Brachial Artery; Cholesterol; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Heart Rate; Homocysteine; Humans; Hyperhomocysteinemia; Luteal Phase; Male; Methionine; Middle Aged; Triglycerides; Vasodilation; Water | 2010 |
Effect of physiological doses of oral vitamin B12 on plasma homocysteine: a randomized, placebo-controlled, double-blind trial in India.
Topics: Adult; Child; Dietary Supplements; Double-Blind Method; Family; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2010 |
Randomized controlled trial of the effect of short-term coadministration of methylcobalamin and folate on serum ADMA concentration in patients receiving long-term hemodialysis.
Topics: Administration, Oral; Aged; Arginine; Cardiovascular Diseases; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors; Vitamin B 12; Vitamin B Complex | 2010 |
Pre-operative vitamin B infusion and prevention of nitrous oxide-induced homocysteine increase.
Topics: Adult; Anesthetics, Inhalation; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitrous Oxide; Preanesthetic Medication; Prospective Studies; Vitamin B 12; Vitamin B Complex | 2010 |
Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Morbidity; Myocardial Infarction; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2010 |
Hyperhomocysteinemia prevalence among patients with venous thromboembolism.
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Factors; Venous Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Effects of oral folate supplementation on serum total homocysteine and cholesterol levels in hyperhomocysteinemic children.
Topics: Child; Cholesterol; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2010 |
A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Hong Kong; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Patient Dropouts; Vitamin B 12; Vitamin B Complex | 2011 |
Elevation of total homocysteine levels in patients with Parkinson's disease treated with duodenal levodopa/carbidopa gel.
Topics: Aged; Antiparkinson Agents; Carbidopa; Drug Combinations; Duodenum; Female; Gels; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 2011 |
Effect of different doses of folic acid on serum homocysteine level in patients on hemodialysis.
Topics: Aged; Aged, 80 and over; Cross-Over Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 2011 |
The association between homocysteine level and metabolic syndrome in patients of prior myocardial infarction.
Topics: Age Factors; Aged; Blood Glucose; Coronary Angiography; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolic Syndrome; Middle Aged; Myocardial Infarction; Regression Analysis; Risk Factors; Sex Factors | 2010 |
Effect of 3 y of folic acid supplementation on the progression of carotid intima-media thickness and carotid arterial stiffness in older adults.
Topics: Aged; Atherosclerosis; Carotid Artery Diseases; Carotid Artery, Common; Dietary Supplements; Disease Progression; Double-Blind Method; Elasticity; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Netherlands; Risk Factors; Tunica Intima; Tunica Media; Ultrasonography | 2011 |
Serum homocysteine and physical exercise in patients with Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Exercise; Female; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Matched-Pair Analysis; Mental Status Schedule; Middle Aged; Parkinson Disease | 2011 |
Does hemodiafiltration improve the removal of homocysteine?
Topics: Adult; Aged; Aged, 80 and over; beta 2-Microglobulin; Cardiovascular Diseases; Cross-Sectional Studies; Female; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Risk Factors | 2011 |
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause | 2012 |
MTHFR C677T and MTR A2756G polymorphisms and the homocysteine lowering efficacy of different doses of folic acid in hypertensive Chinese adults.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Antihypertensive Agents; China; Double-Blind Method; Enalapril; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2012 |
The effect of vitamin B supplementation on homocysteine metabolism and clinical state of patients with chronic epilepsy treated with carbamazepine and valproic acid.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dietary Supplements; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Valproic Acid; Vitamin B 12; Vitamin B Complex; Young Adult | 2012 |
Adverse myocardial effects of B-vitamin therapy in subjects with chronic kidney disease and hyperhomocysteinaemia.
Topics: Aged; Body Mass Index; Cohort Studies; Follow-Up Studies; Heart; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Prospective Studies; Regression Analysis; Renal Insufficiency, Chronic; Serum Albumin; Vitamin B Complex; Vitamins | 2013 |
Vitamin B12 level in peripheral arterial disease.
Topics: Aged; Amino Acid Substitution; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Peripheral Arterial Disease; Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2013 |
[Correlation between long-term proton pump ingibitor use, homocysteine and lipoproteins serum concentrations in patients with comorbidity of ischemic heart disease and acid peptic disease].
Topics: Cholesterol; Comorbidity; Dyslipidemias; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Parenteral; Lipoproteins, LDL; Myocardial Ischemia; Peptic Ulcer; Proton Pump Inhibitors; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
The contribution of portal drained viscera to circadian homocysteinemia in pigs.
Topics: Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Homocysteine; Hyperhomocysteinemia; Portal Vein; Swine; Swine Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Effects of oral N-acetylcysteine on plasma homocysteine and whole blood glutathione levels in healthy, non-pregnant women.
Topics: Acetylcysteine; Administration, Oral; Adult; Antioxidants; Dietary Supplements; Female; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia | 2002 |
Assessment of three levels of folic acid on serum folate and plasma homocysteine: a randomised placebo-controlled double-blind dietary intervention trial.
Topics: Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neural Tube Defects; Nutritional Requirements; Placebos; Vitamin B 12 | 2002 |
Reduction of plasma homocysteine by folic acid in children with chronic renal failure.
Topics: Adolescent; Child; Child, Preschool; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Kidney Failure, Chronic; Male | 2002 |
Vitamin supplementation normalizes total plasma homocysteine concentration but not plasma homocysteine redox status in patients with acute coronary syndromes and hyperhomocysteinemia.
Topics: Acute Disease; Aged; Blood Pressure; Body Mass Index; Coronary Disease; Diabetic Angiopathies; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reference Values; Vitamins | 2002 |
Effect of folic acid therapy on serum homocysteine level in renal transplant recipients.
Topics: Adult; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male | 2002 |
The effect of B-vitamins on hyperhomocysteinemia in patients on antiepileptic drugs.
Topics: Adult; Anticonvulsants; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Methionine; Middle Aged; Pyridoxic Acid; Riboflavin; Selectins; Vascular Cell Adhesion Molecule-1; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2002 |
Hyperhomocysteinemia and endothelial function in young subjects: effects of vitamin supplementation.
Topics: Adolescent; Adult; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 6 | 2002 |
Effects of acute hyperhomocysteinemia on the neurovascular coupling mechanism in healthy young adults.
Topics: Acute Disease; Adult; Blood Flow Velocity; Brain; Cerebrovascular Circulation; Cross-Over Studies; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Photic Stimulation; Posterior Cerebral Artery; Reference Values; Systole; Ultrasonography, Doppler, Transcranial | 2003 |
Vitamin B12 decreases, but does not normalize, homocysteine and methylmalonic acid in end-stage renal disease: a link with glycine metabolism and possible explanation of hyperhomocysteinemia in end-stage renal disease.
Topics: Cysteine; Genotype; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Threonine; Vitamin B 12 | 2003 |
Folic acid treatment reduces elevated plasma levels of asymmetric dimethylarginine in hyperhomocysteinaemic subjects.
Topics: Adult; Aged; Arginine; Biomarkers; Dietary Supplements; Enzyme Inhibitors; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitric Oxide Synthase | 2003 |
The effect of vitamin B12 on total plasma homocysteine concentration in folate-replete hemodialysis patients.
Topics: Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Statistics, Nonparametric; Treatment Outcome; Vitamin B 12 | 2003 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
Topics: Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Linear Models; Male; Middle Aged; Parkinson Disease; Pyridoxal Phosphate; Risk Factors; Vitamin B 12; Vitamin B Complex | 2003 |
Fenofibrate-induced hyperhomocysteinemia may be prevented by folate co-administration.
Topics: Aged; Anticholesteremic Agents; Cross-Over Studies; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Indoles; Male; Middle Aged; Prospective Studies | 2003 |
The effect of PMMA-based protein-leaking dialyzers on plasma homocysteine levels.
Topics: Aged; Aged, 80 and over; Blood Proteins; Dialysis Solutions; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Membranes, Artificial; Middle Aged; Polymethyl Methacrylate; Renal Dialysis; Serum Albumin | 2003 |
Effect of folic acid on fenofibrate-induced elevation of homocysteine and cysteine.
Topics: Cholesterol; Creatinine; Cysteine; Female; Fenofibrate; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Prospective Studies; Statistics as Topic; Triglycerides; Uric Acid | 2003 |
Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine.
Topics: Adult; Age Factors; Aged; Arginine; Arteriosclerosis; Brachial Artery; Endothelium, Vascular; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Peripheral Vascular Diseases; Regional Blood Flow; Regression Analysis; Vasodilation | 2003 |
A 2-step strategy to reduce the need for methionine-loading tests to diagnose hyperhomocysteinemia.
Topics: Adult; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Prospective Studies; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Treatment of hyperhomocysteinemia after renal transplantation.
Topics: Adult; Aged; Creatinine; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Reproducibility of Results; Safety; Time Factors; Vitamin B 12 | 2003 |
Folic acid and vitamin E supplementation effects on homocysteinemia, endothelial function and plasma antioxidant capacity in young myocardial-infarction patients.
Topics: Adult; Antioxidants; Diagnostic Techniques and Procedures; Dietary Supplements; Drug Administration Schedule; Endothelium, Vascular; Female; Folic Acid; Gene Frequency; Genetic Markers; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Pharmacology, Clinical; Uric Acid; Vasodilation; Vitamin E | 2004 |
Randomized, placebo-controlled trial of intramuscular vitamin B12 for the treatment of hyperhomocysteinaemia in dialysis patients.
Topics: Adult; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intramuscular; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2003 |
Effect of homocysteine-lowering vitamin treatment on electrocardiography stress tests in a randomized, placebo-controlled trial: comparison between ST-segment changes and Athen QRS-score.
Topics: Coronary Artery Disease; Double-Blind Method; Electrocardiography; Exercise Test; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 6 | 2004 |
Effects of folic acid fortification and multivitamin therapy on homocysteine and vitamin B(12) status in cardiac transplant recipients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Canada; Cohort Studies; Dietary Supplements; Female; Ferredoxin-NADP Reductase; Folic Acid; Food, Fortified; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamins | 2004 |
Comparative study of response to treatment with supraphysiologic doses of B-vitamins in hyperhomocysteinemic hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
Acute hyperhomocysteinemia induces a reduction in arterial distensibility and compliance.
Topics: Acute Disease; Adult; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Compliance; Cross-Over Studies; Double-Blind Method; Femoral Artery; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Oxidative Stress; Regional Blood Flow; Time Factors; Vasodilation | 2004 |
[Study of the effect of medicinal product "STRESSEN" on blood levels of homocysteine in patients with current cardiovascular disease].
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Drug Combinations; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 12 | 2004 |
[Comparison of treatment with STRESSEN and arginine glutamate on homocysteine blood levels].
Topics: Dipeptides; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Single-Blind Method; Vitamin B 12 | 2004 |
Folate therapy and in-stent restenosis after coronary stenting.
Topics: Aged; Coronary Angiography; Coronary Disease; Coronary Restenosis; Coronary Vessels; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stents; Treatment Failure; Vitamin B 12; Vitamin B 6 | 2004 |
Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Cardiovascular Diseases; Cystathionine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Norway; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2004 |
Dimercaptosuccinic acid for the treatment of hyperhomocysteinemia in hemodialysis patients: a placebo-controlled, double-blind, randomized trial.
Topics: Administration, Oral; Cardiovascular Diseases; Chelating Agents; Double-Blind Method; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors; Succimer; Vitamins | 2004 |
Effects of multivitamins and low-dose folic acid supplements on flow-mediated vasodilation and plasma homocysteine levels in older adults.
Topics: Aged; Aged, 80 and over; Brachial Artery; Dietary Supplements; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prospective Studies; Single-Blind Method; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamins | 2004 |
Evaluation of a shorter methionine loading test.
Topics: Administration, Oral; Adult; Cardiovascular Diseases; Chelating Agents; Edetic Acid; Fasting; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pre-Eclampsia; Pregnancy; Risk Factors; Time Factors | 2004 |
Effect of acute hyperhomocysteinemia on coronary flow reserve in healthy adults.
Topics: Acute Disease; Adult; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Cross-Over Studies; Echocardiography, Doppler; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Placebos | 2004 |
Creatine supplementation does not decrease total plasma homocysteine in chronic hemodialysis patients.
Topics: Aged; Aged, 80 and over; Creatine; Cross-Over Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Nutrition Assessment; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2004 |
Factors associated with increased plasma homocysteine in patients using an amino acid peritoneal dialysis fluid.
Topics: Adult; Amino Acids; Dialysis Solutions; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Function Tests; Male; Malnutrition; Middle Aged; Peritoneal Dialysis; Probability; Prospective Studies; Risk Assessment; Severity of Illness Index; Single-Blind Method; Statistics, Nonparametric; Taiwan; Treatment Outcome | 2005 |
The influence of folate and antioxidants on homocysteine levels and oxidative stress in patients with hyperlipidemia and hyperhomocysteinemia.
Topics: Adult; Aged; Antioxidants; Biomarkers; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress | 2005 |
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation | 2005 |
Homocysteine in chronic kidney disease: Effect of low protein diet and repletion with B vitamins.
Topics: Analysis of Variance; Diet, Protein-Restricted; Dietary Supplements; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Multivariate Analysis; Vitamin B Complex | 2005 |
[Hyperhomocysteinemia and treatment with antiepileptic drugs. Effects of different doses of folic acid].
Topics: Adult; Aged; Anticonvulsants; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2005 |
The effect of entacapone on homocysteine levels in Parkinson disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cohort Studies; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Treatment Outcome | 2005 |
L-folic acid supplementation in healthy postmenopausal women: effect on homocysteine and glycolipid metabolism.
Topics: Blood Glucose; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cysteine; Energy Metabolism; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Middle Aged; Postmenopause; Risk Factors; Risk Reduction Behavior | 2005 |
Plasma homocysteine and markers for oxidative stress and inflammation in patients with coronary artery disease--a prospective randomized study of vitamin supplementation.
Topics: Aged; Biomarkers; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Pyridoxine; Vitamin B 12; Vitamins | 2005 |
Beta blocker effects on plasma homocysteine levels in patients with hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Metoprolol; Middle Aged; Sex Factors; Treatment Outcome | 2005 |
[Efficacy and safety of two vitamin supplement regimens on homocysteine levels in hemodialysis patients. Prospective, randomized clinical trial].
Topics: Aged; Aged, 80 and over; Cohort Studies; Diabetic Nephropathies; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
Homocysteine-lowering therapy and early progression of transplant vasculopathy: a prospective, randomized, IVUS-based study.
Topics: Adult; Cytomegalovirus Infections; Disease Progression; Female; Folic Acid; Heart Diseases; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Hyperplasia; Male; Middle Aged; Prospective Studies; Research Design; Risk Factors; Tetrahydrofolates; Time Factors; Ultrasonography; Vascular Diseases | 2005 |
Experimental hyperhomocysteinemia impairs coronary flow velocity reserve.
Topics: Adenosine Triphosphate; Administration, Oral; Adult; Antioxidants; Ascorbic Acid; Biomarkers; Blood Flow Velocity; Coronary Circulation; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Oxidative Stress; Reference Values; Research Design; Superoxide Dismutase; Time Factors | 2005 |
Hyperhomocysteinemia in children treated with antiepileptic drugs is normalized by folic acid supplementation.
Topics: Anticonvulsants; Child; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Treatment Outcome; Vitamin B 12 | 2005 |
Efficacy of B vitamins in lowering homocysteine in older men: maximal effects for those with B12 deficiency and hyperhomocysteinemia.
Topics: Aged; Dietary Supplements; Double-Blind Method; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Homocysteine levels in acromegaly patients.
Topics: Acromegaly; Adult; Cardiovascular Diseases; Female; Glucose Tolerance Test; Growth Hormone; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Statistics, Nonparametric | 2005 |
Determining factors of the response to hyperhomocysteinemia treatment in renal transplant patients.
Topics: Adult; Aged; Analysis of Variance; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; ROC Curve; Treatment Outcome; Vitamin B 12 | 2005 |
Preliminary results of the effect of treatment of hyperhomocysteinemia and its relationship with inflammation, coagulation status, and endothelial function after renal transplantation.
Topics: Adult; Aged; Biomarkers; Blood Coagulation; Blood Coagulation Disorders; Brachial Artery; Creatinine; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prospective Studies; Vitamin B 12 | 2005 |
Effects of short-term folic acid and/or riboflavin supplementation on serum folate and plasma total homocysteine concentrations in young Japanese male subjects.
Topics: Adult; Alanine Transaminase; Dietary Supplements; Double-Blind Method; Drug Interactions; Erythrocytes; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Riboflavin; Vitamin B Complex | 2006 |
Methylenetetrahydrofolate reductase polymorphisms and homocysteine-lowering effect of vitamin therapy in Singaporean stroke patients.
Topics: Aged; Coronary Artery Disease; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Middle Aged; Models, Statistical; Placebos; Polymorphism, Genetic; Regression Analysis; Risk Factors; Singapore; Stroke; Vitamin B 12; Vitamin B 6; Vitamins | 2006 |
Homocysteine-reducing strategies improve symptoms in chronic schizophrenic patients with hyperhomocysteinemia.
Topics: Adult; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Pyridoxine; Schizophrenia; Schizophrenic Psychology; Time Factors; Vitamin B 12; Vitamin B Complex | 2006 |
Mild hyperhomocysteinemia is associated with a decreased fibrinolytic activity in patients after ST-elevation myocardial infarction.
Topics: Adult; Aged; Coronary Artery Disease; Female; Fibrinolysis; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Risk Factors; Tissue Plasminogen Activator | 2007 |
No effect of homocysteine-lowering therapy on vascular inflammation and haemostasis in peripheral arterial occlusive disease.
Topics: Aged; Arterial Occlusive Diseases; Biomarkers; Chronic Disease; Drug Therapy, Combination; Female; Folic Acid; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation Mediators; Male; Middle Aged; Patient Compliance; Peripheral Vascular Diseases; Vasculitis; Vitamin B Complex | 2006 |
Folic acid 5 or 15 mg/d similarly reduces plasma homocysteine in patients with moderate-advanced chronic renal failure.
Topics: Aged; Double-Blind Method; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Middle Aged; Renal Replacement Therapy; Vitamin B Complex | 2006 |
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study.
Topics: Aged; Antiparkinson Agents; Canada; Catechols; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Placebo Effect; Treatment Outcome; United States; Vitamin B 12; Vitamins | 2006 |
A controlled trial of homocysteine lowering and cognitive performance.
Topics: Aged; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Psychological Tests; Vitamin B 12; Vitamin B Complex | 2006 |
Direct, reverse or reciprocal causation in the relation between homocysteine and ischemic heart disease.
Topics: Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Ischemia; Risk Factors | 2007 |
Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Proportional Hazards Models; Pulmonary Embolism; Pyridoxine; Recurrence; Risk Factors; Thrombophilia; Treatment Failure; Venous Thrombosis; Vitamin B 12 | 2007 |
Pro-thrombotic and pro-oxidant effects of diet-induced hyperhomocysteinemia.
Topics: Animals; Antioxidants; Ascorbic Acid; Caspase 3; Choline Deficiency; Diet; Disease Models, Animal; Female; Fibrinolysis; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Mitochondria; Oxidative Stress; Rabbits; Risk Factors; Thrombosis; Vitamin E | 2007 |
B-vitamin status and concentrations of homocysteine in Austrian omnivores, vegetarians and vegans.
Topics: Adult; Aged; Alcohol Drinking; Anthropometry; Aspartate Aminotransferases; Austria; Diet; Diet, Vegetarian; Feeding Behavior; Female; Folic Acid; Glutathione Reductase; Homocysteine; Humans; Hyperhomocysteinemia; Male; Meat; Middle Aged; Pyridoxal Phosphate; Pyridoxic Acid; Riboflavin; Riboflavin Deficiency; Surveys and Questionnaires; Thiamine; Transketolase; Vegetables; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2006 |
Asymmetrical dimethylarginine regulates endothelial function in methionine-induced but not in chronic homocystinemia in humans: effect of oxidative stress and proinflammatory cytokines.
Topics: Adult; alpha-Tocopherol; Arginine; Ascorbic Acid; Cholesterol, LDL; Chronic Disease; Cytokines; Double-Blind Method; Endothelium, Vascular; Female; Forearm; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-6; Male; Methionine; Oxidative Stress; Time Factors; Vascular Resistance; von Willebrand Factor | 2006 |
Lack of significant effects of methionine loading on endothelial function in elderly volunteers.
Topics: Aged; Aged, 80 and over; Brachial Artery; C-Reactive Protein; Cholesterol; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Methionine; Placebos; Regional Blood Flow; Time Factors; Triglycerides | 2006 |
Effect of short-term folate and vitamin B supplementation on blood homocysteine level and carotid artery wall thickness in chronic hemodialysis patients.
Topics: Atherosclerosis; Carotid Arteries; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Treatment Outcome; Ultrasonography; Vitamin B 12; Vitamin B 6 | 2006 |
A single-center, double-blinded, randomized controlled study to evaluate the relative efficacy of sublingual and oral vitamin B-complex administration in reducing total serum homocysteine levels.
Topics: Administration, Oral; Administration, Sublingual; Aged; Aged, 80 and over; Atherosclerosis; Dietary Supplements; Double-Blind Method; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Treatment Outcome; Vitamin B Complex | 2006 |
Effect of fortified spread on homocysteine concentration in apparently healthy volunteers.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine, MTHFR C677 T, vitamin B12, and folate levels in Thai children with ischemic stroke: a case-control study.
Topics: Adolescent; Child; Child, Preschool; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Ischemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors; Stroke; Thailand; Thrombosis; Vitamin B 12 | 2006 |
Oral vitamin B12 supplementation reduces plasma total homocysteine concentration in women in India.
Topics: Administration, Oral; Adult; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Middle Aged; Prevalence; Treatment Outcome; Vegetables; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2007 |
Folic acid therapy reduces plasma homocysteine levels and improves plasma antioxidant capacity in hemodialysis patients.
Topics: Cardiovascular Diseases; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hydrogen Peroxide; Hyperhomocysteinemia; Lipid Peroxidation; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Renal Dialysis; Time Factors; Vitamin B Complex | 2007 |
The risk of recurrent cardiovascular events in patients with increased plasma homocysteine levels is reduced by short but not long-term therapy with folate and B vitamins.
Topics: Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Recurrence; Risk Factors; Time Factors; Treatment Outcome; Vitamin B Complex | 2007 |
The folic acid metabolite L-5-methyltetrahydrofolate effectively reduces total serum homocysteine level in orthotopic liver transplant recipients: a double-blind placebo-controlled study.
Topics: Chromatography, High Pressure Liquid; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Transplantation; Male; Middle Aged; Prospective Studies; Tetrahydrofolates; Treatment Outcome | 2008 |
[Evaluation of the influence of sex hormones on homocysteine concentration in pre- and postmenopausal women].
Topics: Dehydroepiandrosterone Sulfate; Estrogen Replacement Therapy; Estrogens; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Homocysteine; Humans; Hydrocortisone; Hyperhomocysteinemia; Male; Middle Aged; Postmenopause; Premenopause; Progesterone; Testosterone | 2005 |
Randomized clinical trial of homocysteine level lowering therapy and fractures.
Topics: Aged; Cardiovascular Diseases; Drug Therapy, Combination; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Proportional Hazards Models; Pyridoxine; Risk Factors; Treatment Outcome; Vitamin B 12 | 2007 |
Effects of folic acid and N-acetylcysteine on plasma homocysteine levels and endothelial function in patients with coronary artery disease.
Topics: Acetylcysteine; Administration, Oral; Aged; Coronary Artery Disease; Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2007 |
[Hyperhomocysteinemia--one of the factors underlying thrombotic complications in patients with chronic myeloproliferative diseases].
Topics: Adolescent; Adult; Biomarkers; Chronic Disease; DNA; Factor V; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myeloproliferative Disorders; Platelet Count; Point Mutation; Polymerase Chain Reaction; Prognosis; Prothrombin; Thrombosis | 2007 |
Effect of folic acid in women with and without insulin resistance who have hyperhomocysteinemic polycystic ovary syndrome.
Topics: Adolescent; Adult; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Insulin Resistance; Polycystic Ovary Syndrome; Prospective Studies; Vitamin B Complex | 2008 |
Omega-3 fatty acid supplementation and total homocysteine levels in end-stage renal disease patients.
Topics: Aged; Corn Oil; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Nonprescription Drugs; Prospective Studies; Renal Dialysis; Texas; Time Factors; Treatment Outcome; Up-Regulation | 2008 |
Mesna for treatment of hyperhomocysteinemia in hemodialysis patients: a placebo-controlled, double-blind, randomized trial.
Topics: Aged; Double-Blind Method; Drug Administration Schedule; Female; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intravenous; Kidney Failure, Chronic; Male; Mesna; Renal Dialysis; Treatment Outcome | 2008 |
Effect of nitrous oxide on plasma homocysteine and folate in patients undergoing major surgery.
Topics: Adult; Aged; Anesthetics, Inhalation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intraoperative Period; Male; Middle Aged; Nitrous Oxide; Postoperative Complications; Risk Assessment; Risk Factors | 2008 |
Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy.
Topics: Adult; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Oxidative Stress; Time Factors | 1999 |
Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients.
Topics: Adult; Betaine; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome | 1999 |
Atherothrombogenic risk modulation by n-3 fatty acids was not associated with changes in homocysteine in subjects with combined hyperlipidaemia.
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Bleeding Time; Body Mass Index; Double-Blind Method; Fatty Acids; Fatty Acids, Omega-3; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Middle Aged; Patient Compliance; Phospholipids; Plasminogen Activator Inhibitor 1; Platelet Count; Risk Factors; Thrombosis; Triglycerides | 1999 |
Plasma total homocysteine response to oral doses of folic acid and pyridoxine hydrochloride (vitamin B6) in healthy individuals. Oral doses of vitamin B6 reduce concentrations of serum folate.
Topics: Administration, Oral; Adult; Cholesterol; Cysteine; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Middle Aged; Norway; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Vitamin B 12 | 1999 |
Hyperhomocysteinemia in high-aged subjects: relation of B-vitamins, folic acid, renal function and the methylenetetrahydrofolate reductase mutation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Regression Analysis; Risk Assessment; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 1999 |
Serum homocysteine increases after therapy with fenofibrate or bezafibrate.
Topics: Adult; Bezafibrate; Chromatography, High Pressure Liquid; Fenofibrate; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Hypertriglyceridemia; Hypolipidemic Agents; Male; Middle Aged; Pilot Projects; Pyridoxine; Vitamin B 12 | 1999 |
Variability of fasting and post-methionine plasma homocysteine levels in normo- and hyperhomocysteinaemic individuals.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Analysis of Variance; Fasting; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases; Statistics, Nonparametric | 1999 |
Total homocysteine is associated with nephropathy in non-insulin-dependent diabetes mellitus.
Topics: Adult; Aged; Albuminuria; Cystathionine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney Function Tests; Male; Methylmalonic Acid; Middle Aged; Regression Analysis; Vitamins | 1999 |
Folic acid improves arterial endothelial function in adults with hyperhomocystinemia.
Topics: Administration, Oral; Adult; Aged; Arteriosclerosis; Brachial Artery; Cholesterol; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Observer Variation; Treatment Outcome; Ultrasonography; Vasodilation | 1999 |
Enhanced reduction of fasting total homocysteine levels with supraphysiological versus standard multivitamin dose folic acid supplementation in renal transplant recipients.
Topics: Adult; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Logistic Models; Male; Middle Aged; Postoperative Complications; Renal Dialysis; Renal Insufficiency | 1999 |
Low-dose folic acid supplementation does not influence plasma methionine concentrations in young non-pregnant women.
Topics: Adolescent; Adult; Contraceptives, Oral; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Vitamin B 12 | 1999 |
Dietary strategies for lowering homocysteine concentrations.
Topics: Adult; Aged; Blood Glucose; Body Weight; Diet; Dietary Supplements; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Lipoproteins; Male; Middle Aged; Vitamin B 12 | 2000 |
Hyperhomocysteinemia and other thrombotic risk factors in women with placental vasculopathy.
Topics: Activated Protein C Resistance; Adult; Antithrombin III; Case-Control Studies; Factor V; Female; Homocysteine; Humans; Hyperhomocysteinemia; Mutation; Placenta; Placenta Diseases; Pregnancy; Protein C; Protein S; Risk Factors; Tetrahydrofolates; Thrombosis | 2000 |
Controlled comparison of L-5-methyltetrahydrofolate versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Dialysis; Tetrahydrofolates; Treatment Failure | 2000 |
A controlled trial of the effect of folate supplements on homocysteine, lipids and hemorheology in end-stage renal disease.
Topics: Adult; Aged; Arteriosclerosis; Double-Blind Method; Female; Folic Acid; Hemorheology; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipids; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Risk Factors | 2000 |
Hyperhomocysteinemia in hemodialysis patients: effects of 12-month supplementation with hydrosoluble vitamins.
Topics: Aged; Cohort Studies; Female; Folic Acid; Follow-Up Studies; Genotype; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Renal Dialysis; Solubility; Vitamin B Complex | 2000 |
Homocysteine and venous thrombosis: outline of a vitamin intervention trial.
Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Netherlands; Prospective Studies; Pulmonary Embolism; Pyridoxine; Retrospective Studies; Secondary Prevention; Thrombophilia; Thrombophlebitis; Treatment Outcome; Ultrasonography; Venous Thrombosis; Vitamin B 12 | 2000 |
Oxidative stress and an altered methionine metabolism in alcoholism.
Topics: Adult; Aged; Alcoholism; Chlormethiazole; Chromatography, High Pressure Liquid; Chronic Disease; Ethanol; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypnotics and Sedatives; Lipid Peroxidation; Male; Malondialdehyde; Methionine; Middle Aged; Oxidative Stress | 2000 |
Rapid communication: L-folinic acid versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leucovorin; Male; Middle Aged; Renal Dialysis; Treatment Outcome | 2001 |
Plasma homocysteine concentrations in the acute and convalescent periods of atherothrombotic stroke.
Topics: Acute Disease; Adult; Aged; Arteriosclerosis; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Convalescence; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Lipids; Male; Middle Aged; Regression Analysis; Risk Factors; Scotland; Stroke; Stroke Rehabilitation; Tomography, X-Ray Computed; Vitamin B 12 | 2001 |
Oral vitamin B(12) and high-dose folic acid in hemodialysis patients with hyper-homocyst(e)inemia.
Topics: Administration, Oral; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Dialysis; Vitamin B 12 | 2001 |
Hyperhomocysteinemia in poorly controlled type 2 diabetes patients.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Risk Factors | 2000 |
Parenteral vitamin B12 reduces hyperhomocysteinemia in end-stage renal disease.
Topics: Cysteine; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Subcutaneous; Kidney Failure, Chronic; Methylmalonic Acid; Renal Dialysis; Vitamin B 12 | 2001 |
Efficacy of folinic versus folic acid for the correction of hyperhomocysteinemia in hemodialysis patients.
Topics: Double-Blind Method; Drug Administration Schedule; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Leucovorin; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Renal Dialysis; Treatment Outcome; Vitamin B 12 | 2001 |
Homocysteine lowering effect of different multivitamin preparations in patients with end-stage renal disease.
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Pyridoxine; Renal Dialysis; Vitamin B 12 | 2001 |
Risk assessment of alcohol withdrawal seizures with a Kohonen feature map.
Topics: Adult; Aged; Alcohol Withdrawal Seizures; Alcoholism; Algorithms; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Neural Networks, Computer; Risk Assessment; Statistics, Nonparametric | 2001 |
Hyperhomocysteinemia and changed plasma thiol redox status in chronic obstructive pulmonary disease.
Topics: Aged; Aged, 80 and over; Cysteine; Dipeptides; Female; Free Radicals; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Lung Diseases, Obstructive; Male; Middle Aged; Oxidation-Reduction; Sulfhydryl Compounds | 2001 |
The effect on endothelial function of vitamin C during methionine induced hyperhomocysteinaemia.
Topics: Acetylcholine; Administration, Oral; Adult; Area Under Curve; Ascorbic Acid; Cross-Over Studies; Endothelium, Vascular; Forearm; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intra-Arterial; Male; Methionine; Oxidative Stress; Plethysmography; Regional Blood Flow; Single-Blind Method; Vasodilation | 2001 |
Homocysteine levels in patients treated with lipid apheresis: effect of a vitamin therapy.
Topics: Adult; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipoproteinemia Type II; Lipids; Male; Vitamin B 12; Vitamin B 6 | 2001 |
Increasing homocysteine levels and diabetic autonomic neuropathy.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Renal; Logistic Models; Male; Middle Aged; Prospective Studies; Risk Factors | 2001 |
Cerebrovascular events in patients with significant stenosis of the carotid artery are associated with hyperhomocysteinemia and platelet antigen-1 (Leu33Pro) polymorphism.
Topics: Aged; Amino Acid Substitution; Antibodies, Antiphospholipid; Antigens, Human Platelet; Carotid Stenosis; Comorbidity; Factor V; Female; Homocysteine; Humans; Hyperhomocysteinemia; Integrin beta3; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Platelet Membrane Glycoproteins; Polymorphism, Genetic; Prothrombin; Risk Assessment; Risk Factors; Stroke | 2001 |
Long-term homocysteine-lowering treatment with folic acid plus pyridoxine is associated with decreased blood pressure but not with improved brachial artery endothelium-dependent vasodilation or carotid artery stiffness: a 2-year, randomized, placebo-contr
Topics: Adult; Blood Pressure; Brachial Artery; Carotid Arteries; Drug Therapy, Combination; Elasticity; Endothelium, Vascular; Female; Folic Acid; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pyridoxine; Vasodilation | 2001 |
Decreased rate of coronary restenosis after lowering of plasma homocysteine levels.
Topics: Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Pyridoxine; Vitamin B 12 | 2001 |
Treatment of hyperhomocysteinemia with folic acid reduces oxidative stress in renal transplant recipients.
Topics: Adult; Antioxidants; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Oxidative Stress; Postoperative Complications; Time Factors | 2002 |
Risk factors for progression of aortic atheroma in stroke and transient ischemic attack patients.
Topics: Anticoagulants; Aortic Diseases; Arteriosclerosis; Demography; Disease Progression; Echocardiography, Transesophageal; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Remission, Spontaneous; Risk Factors; Stroke; Treatment Outcome | 2002 |
Influence of mycophenolic acid and tacrolimus on homocysteine metabolism.
Topics: Adult; Cells, Cultured; Enzyme Inhibitors; Female; Graft Rejection; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubules, Proximal; Male; Middle Aged; Mycophenolic Acid; Tacrolimus | 2002 |
Hydroxocobalamin reduces hyperhomocysteinemia in end-stage renal disease.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Injections, Subcutaneous; Kidney Failure, Chronic; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12 | 2002 |
1810 other study(ies) available for homocysteine and Hyperhomocysteinemia
| Article | Year |
|---|---|
Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia.
Topics: Amidohydrolases; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Drug Design; Homocysteine; Humans; Hydrogen Peroxide; Hyperhomocysteinemia; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
Prevalence of hyperhomocysteinemia (HHcy) and its major determinants among hypertensive patients over 35 years of age.
Topics: Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Prevalence; Risk Factors; Vitamin B 12 | 2022 |
Voluntary Exercise Attenuates Hyperhomocysteinemia, But Does not Protect Against Hyperhomocysteinemia-Induced Testicular and Epididymal Disturbances.
Topics: Animals; Catalase; Epididymis; Homocysteine; Hyperhomocysteinemia; Male; Mice; Oxidative Stress; Physical Conditioning, Animal; Testis; Testosterone; Thiobarbituric Acid Reactive Substances | 2022 |
Implication of
Topics: Aged; Aged, 80 and over; Animals; Cell Line; Choroidal Neovascularization; Cystathionine beta-Synthase; Disease Models, Animal; Endothelial Cells; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoxia-Inducible Factor 1, alpha Subunit; Macular Degeneration; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Neovascularization, Pathologic; Primary Cell Culture; Receptors, N-Methyl-D-Aspartate; Retinal Pigment Epithelium; Vascular Endothelial Growth Factor A | 2021 |
Distribution characteristics and influencing factors of homocyteine in an apparently healthy examined population.
Topics: Adult; Age Factors; Aged; Biomarkers; Cardiovascular Diseases; China; Cholesterol, HDL; Creatinine; Female; Healthy Volunteers; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Middle Aged; Risk Assessment; Risk Factors; Sex Factors; Uric Acid; Young Adult | 2021 |
Combined effect of hyperhomocysteinemia and smoking on the severity of coronary artery disease in young adults ≤ 35 years of age: a hospital-based observational study.
Topics: Adolescent; Adult; Age of Onset; Beijing; Biomarkers; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Smoking; Young Adult | 2021 |
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation.
Topics: Adipose Tissue; Animals; Antigens, CD; CHO Cells; Cricetulus; Diabetes Mellitus, Type 2; Disease Models, Animal; Furin; HEK293 Cells; Hep G2 Cells; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Liver; Male; Mice, Inbred C57BL; Muscle, Skeletal; Protein Processing, Post-Translational; Rats; Receptor, Insulin | 2021 |
Exosome Biogenesis and Lysosome Function Determine Podocyte Exosome Release and Glomerular Inflammatory Response during Hyperhomocysteinemia.
Topics: Animals; Exosomes; Homocysteine; Hyperhomocysteinemia; Inflammasomes; Inflammation; Kidney Glomerulus; Lysosomes; Male; Mice, Inbred C57BL; Multivesicular Bodies; NLR Family, Pyrin Domain-Containing 3 Protein; Podocytes; Sphingomyelin Phosphodiesterase | 2022 |
Homocysteine Solution-Induced Response in Aerosol Jet Printed OECTs by Means of Gold and Platinum Gate Electrodes.
Topics: Dielectric Spectroscopy; Electrochemical Techniques; Electrodes; Gold; Homocysteine; Humans; Hyperhomocysteinemia; Platinum; Point-of-Care Systems; Printing, Three-Dimensional; Transistors, Electronic | 2021 |
The Link between Exercise and Homocysteine in the Alzheimer's Disease: A Bioinformatic Network Model.
Topics: Alzheimer Disease; Brain; Cognitive Dysfunction; Computational Biology; Exercise; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress | 2021 |
The roles of homocysteinemia and methylmalonic acidemia in kidney injury in atypical hemolytic uremic syndrome caused by cobalamin C deficiency.
Topics: Acute Kidney Injury; Amino Acid Metabolism, Inborn Errors; Atypical Hemolytic Uremic Syndrome; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Kidney; Methylmalonic Acid; Oxidoreductases; Thrombotic Microangiopathies; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Association of air pollution and homocysteine with global DNA methylation: A population-based study from North India.
Topics: Adult; Aged; Air Pollution; Cross-Sectional Studies; DNA Methylation; Female; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Vitamin B 12 Deficiency | 2021 |
Prevalence and risk factors for hyperhomocysteinemia: a population-based cross-sectional study from Hunan, China.
Topics: China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Factors | 2021 |
Ameliorative Effect of Acetyl L-carnitine in Alzheimer's Disease via Downregulating of Homocysteine Levels in Hyperhomocysteinemia Induced Cognitive Deficit in Mouse Model.
Topics: Acetylcarnitine; Acetylcholinesterase; Alzheimer Disease; Animals; Cognition; Homocysteine; Hyperhomocysteinemia; Mice; Neuroinflammatory Diseases | 2021 |
New Evidence for Homocysteine Lowering for Management of Treatment-Resistant Hypertension.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Vitamin B Complex | 2022 |
Association Between Hyperhomocysteinemia Combined with Metabolic Syndrome and Higher Prevalence of Stroke in Chinese Adults Who Have Elevated Blood Pressure.
Topics: Aged; Biomarkers; Blood Pressure Determination; China; Comorbidity; Correlation of Data; Female; Heart Disease Risk Factors; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Metabolic Syndrome; Prevalence; Risk Assessment; Stroke | 2022 |
Homocysteine Suppresses Autophagy Through AMPK-mTOR-TFEB Signaling in Human THP-1 Macrophages.
Topics: AMP-Activated Protein Kinases; Atherosclerosis; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Child; Homocysteine; Humans; Hyperhomocysteinemia; Macrophages; Signal Transduction; TOR Serine-Threonine Kinases | 2022 |
Association between Elevated Plasma Homocysteine and Low Skeletal Muscle Mass in Asymptomatic Adults.
Topics: Adult; Cross-Sectional Studies; Homocysteine; Humans; Hyperhomocysteinemia; Muscle, Skeletal; Odds Ratio | 2022 |
Severe Hyperhomocysteinemia in a Patient with Parkinson Disease.
Topics: Drug Combinations; Homocysteine; Humans; Hyperhomocysteinemia; Parkinson Disease | 2022 |
A Descriptive Study of Total Serum Homocysteine Status in Adult Henan Province, China.
Topics: Adult; China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Factors; Young Adult | 2022 |
RBC Folate and Serum Folate, Vitamin B-12, and Homocysteine in Chinese Couples Prepregnancy in the Shanghai Preconception Cohort.
Topics: Biomarkers; China; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Vitamin B12 and chronic kidney disease.
Topics: Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Renal Insufficiency, Chronic; Vitamin B 12 | 2022 |
Homocysteine-Induced Disturbances in DNA Methylation Contribute to Development of Stress-Associated Cognitive Decline in Rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; DNA Methylation; Homocysteine; Hyperhomocysteinemia; Rats; Stress, Psychological | 2022 |
A Study of Srum Homocysteine Level in Ischaemic Stoke.
Topics: Aged; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Ischemic Stroke; Lipids; Risk Factors; Stroke; Vitamin B 12 | 2022 |
Plasma homocysteine levels and handgrip strength in postmenopausal women.
Topics: Creatinine; Female; Hand Strength; Homocysteine; Humans; Hyperhomocysteinemia; Postmenopause; Prospective Studies | 2022 |
Rivastigmine Reverses the Decrease in Synapsin and Memory Caused by Homocysteine: Is There Relation to Inflammation?
Topics: Acetylcholinesterase; Animals; Homocysteine; Hyperhomocysteinemia; Ibuprofen; Inflammation; Male; Oxidative Stress; Rats; Rats, Wistar; Rivastigmine; Synapsins | 2022 |
Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats.
Topics: Animals; Anxiety; Cortical Excitability; Female; Homocysteine; Hyperalgesia; Hyperhomocysteinemia; Migraine Disorders; Nitroglycerin; Photophobia; Pregnancy; Rats | 2022 |
Homocysteine Metabolism Pathway Is Involved in the Control of Glucose Homeostasis: A Cystathionine Beta Synthase Deficiency Study in Mouse.
Topics: Animals; Cystathionine beta-Synthase; Diabetes Mellitus, Type 2; Glucose; Homeostasis; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Mice | 2022 |
Prevalence and correlative factors of hyperhomocysteinemia in elderly patients with femoral neck fracture: A cross-sectional study.
Topics: Aged; Cross-Sectional Studies; Female; Femoral Neck Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Prevalence; Retrospective Studies; Risk Factors | 2022 |
The role of methylenetetrahydrofolate reductase C677T gene polymorphism as a risk factor for coronary artery disease: a cross-sectional study in the Sidoarjo Regional General Hospital.
Topics: Case-Control Studies; Coronary Artery Disease; Cross-Sectional Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic | 2022 |
Fetal hyperhomocysteinemia is associated with placental inflammation and early breakdown of maternal-fetal tolerance in pre-term birth.
Topics: Biomarkers; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Placenta; Pregnancy; Premature Birth; Term Birth; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vitamin B 12 | 2022 |
Effects of four weeks lasting aerobic physical activity on cardiovascular biomarkers, oxidative stress and histomorphometric changes of heart and aorta in rats with experimentally induced hyperhomocysteinemia.
Topics: Animals; Aorta; Biomarkers; Exercise; Homocysteine; Hyperhomocysteinemia; Male; Oxidative Stress; Rats; Rats, Wistar; Saline Solution | 2023 |
Comparison of the Levels of Blood Homocysteine between Women with Unexplained Infertility and Normal Fertility.
Topics: Cross-Sectional Studies; Female; Fertility; Homocysteine; Humans; Hyperhomocysteinemia; Infertility, Female; Pregnancy | 2022 |
Vitamin B
Topics: Animals; Fatty Acids; Fibrosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Qa-SNARE Proteins; Vitamin B 12; Vitamins | 2022 |
Relationships of Serum Homocysteine, Vitamin B
Topics: Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Rosacea; Vitamin B 12; Vitamins | 2022 |
Relationship between hyperhomocysteinemia and coexisting obesity with low skeletal muscle mass in asymptomatic adult population.
Topics: Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Muscle, Skeletal; Obesity; Risk Factors | 2022 |
Proton pump inhibitor use and its effect on vitamin B12 and homocysteine levels among men and women: A large cross-sectional study.
Topics: Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Proton Pump Inhibitors; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Effect of hyperhomocysteinemia on a murine model of smoke-induced pulmonary emphysema.
Topics: Animals; Apoptosis; Disease Models, Animal; Emphysema; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Nicotiana; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema | 2022 |
The Protective Effects of Acetazolamide Against Homocysteine-Induced Blood-Brain-Barrier Disruption by Regulating the Activation of the Wnt/β-Catenin Signaling Pathway.
Topics: Acetazolamide; Animals; beta Catenin; Blood-Brain Barrier; Brain Diseases; Carbonic Anhydrase Inhibitors; Claudin-5; Endothelial Cells; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Neuroprotective Agents; Occludin; Rats; Wnt Signaling Pathway | 2022 |
Hyperhomocysteinemia in acute hepatic porphyria (AHP) and implications for treatment with givosiran.
Topics: Clinical Trials as Topic; Cystathionine beta-Synthase; Folic Acid; Heme; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Porphyrias, Hepatic; Pyridoxine; RNA, Small Interfering; Sulfur; Vitamin B 6 | 2022 |
Dose-response association between plasma homocysteine and white matter lesions in patients with hypertension: a case-control study.
Topics: Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; White Matter | 2022 |
Hyperhomocysteinemia Promotes Cardiac Hypertrophy in Hypertension.
Topics: Animals; Calcineurin; Cardiomegaly; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Mice; Myocytes, Cardiac; NFATC Transcription Factors; Rats; Retrospective Studies | 2022 |
Elevated homocysteine activates unfolded protein responses and causes aberrant trophoblast differentiation and mouse blastocyst development.
Topics: Animals; Blastocyst; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Placenta; Pregnancy; Trophoblasts; Unfolded Protein Response; Vitamins | 2022 |
Serum Homocysteine, Vitamin B12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia.
Topics: Alzheimer Disease; Cognitive Dysfunction; Dementia, Vascular; Folic Acid; Frontotemporal Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2022 |
Distribution and Determinants of Plasma Homocysteine Levels in a Preconception Population: A Retrospective Single-Center Study.
Topics: China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Retrospective Studies | 2022 |
Elevated homocysteine levels: What inborn errors of metabolism might we be missing?
Topics: Adult; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Metabolism, Inborn Errors; Retrospective Studies; Vitamin B 12 | 2023 |
The Presence of Hyperhomocysteinemia Does Not Aggravate the Cardiometabolic Risk Imposed by Hyperuricemia in Young Individuals: A Retrospective Analysis of a Cross-Sectional Study.
Topics: Biomarkers; Blood Glucose; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hyperuricemia; Insulins; Lipids; Male; Metabolic Syndrome; Retrospective Studies; Risk Factors; Uric Acid | 2022 |
Homocysteine promotes migration of adventitial fibroblasts via angiotensin II type 1 receptor activation to aggravate atherosclerosis.
Topics: Adventitia; Atherosclerosis; Fibroblasts; Homocysteine; Humans; Hyperhomocysteinemia; Receptor, Angiotensin, Type 1; Telmisartan | 2022 |
Hyperhomocysteinemia predicts liver-related clinical outcomes in the general population.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Liver; Vitamin B Complex | 2023 |
The role of the deficiency of vitamin B12 and folic acid on homocysteinemia in children with Turner syndrome.
Topics: Child; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Turner Syndrome; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
HOMOCYSTEINE LEVEL IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME WITH AND WITHOUT INSULIN RESISTANCE.
Topics: Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hyperinsulinism; Insulin; Insulin Resistance; Polycystic Ovary Syndrome; Young Adult | 2022 |
Relationship between plasma homocysteine and chronic kidney disease in US patients with type 2 diabetes mellitus: a cross-sectional study.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutrition Surveys; Renal Insufficiency, Chronic | 2022 |
The relationship between hyperhomocysteinemia and total coronary artery occlusion: a cross-sectional study from Southwest China.
Topics: Adult; Aged; China; Coronary Artery Disease; Coronary Occlusion; Cross-Sectional Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Overweight; Risk Factors | 2023 |
Warburg Effect as a Novel Mechanism for Homocysteine-Induced Features of Age-Related Macular Degeneration.
Topics: Animals; Cells, Cultured; Choroidal Neovascularization; Cystathionine beta-Synthase; Homocysteine; Hyperhomocysteinemia; Macular Degeneration; Mice; Retinal Pigment Epithelium | 2023 |
Using Bayesian networks with Tabu-search algorithm to explore risk factors for hyperhomocysteinemia.
Topics: Algorithms; Bayes Theorem; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Smoking | 2023 |
Mechanism of arterial injury exacerbated by hyperhomocysteinemia in spontaneously hypertensive rats.
Topics: Animals; Homocysteine; Hyperhomocysteinemia; Hypertension; Inflammation; Interleukin-6; NF-kappa B; Rats; Rats, Inbred SHR; Vascular System Injuries | 2023 |
Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
Topics: Adult; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Prospective Studies; Republic of Korea; Risk Factors | 2023 |
A Potential Strategy for Atherosclerosis Prevention in Modernizing China - Hyperhomocysteinemia, MTHFR C677T Polymorphism and Air Pollution (PM2.5) on Atherogenesis in Chinese Adults.
Topics: Air Pollution; Atherosclerosis; Carotid Intima-Media Thickness; East Asian People; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Particulate Matter | 2023 |
Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Betaine; Glucose; Homocysteine; Hypercholesterolemia; Hyperhomocysteinemia; Liver; Mutation; Phosphoprotein Phosphatases; Rats; Rats, Inbred BN; Sarcosine; Sarcosine Dehydrogenase | 2023 |
MiR
Topics: Animals; Apoptosis; Autophagy; bcl-2-Associated X Protein; Homocysteine; Hyperhomocysteinemia; MicroRNAs; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species | 2023 |
Homocysteine Levels in Severe OSA Patients Before and After TORS-OSA Surgery.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Retrospective Studies; Robotic Surgical Procedures; Sleep Apnea, Obstructive; Treatment Outcome | 2023 |
Cerebral venous thrombosis with hyperhomocysteinemia due to loss of heterozygosity at methylenetetrahydrofolate reductase (MTHFR) locus: a case report.
Topics: Adolescent; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Loss of Heterozygosity; Methylenetetrahydrofolate Reductase (NADPH2); Venous Thrombosis | 2023 |
Ischaemic stroke with multi-focal venous and arterial thrombosis due to hyperhomocysteinemia: anabolic androgenic steroid use and MTHFR c.667 C > T variant - a case report.
Topics: Anabolic Androgenic Steroids; Brain Ischemia; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Stroke; Male; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Stroke; Thrombosis; Vitamin B 12 | 2023 |
Dapagliflozin's effect on serum homocysteine in patients with hypertension complicated with insulin resistance.
Topics: Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin Resistance; Retrospective Studies | 2023 |
Folic acid enhances the cardiovascular protective effect of amlodipine in renal hypertensive rats with elevated homocysteine.
Topics: Amlodipine; Animals; Endothelial Cells; Folic Acid; Homocysteine; Hyperhomocysteinemia; Hypertension; Kidney; Rats | 2023 |
In Situ Fluorescence Imaging Reveals Contribution of Cerebral Hydroxyl Radicals in Hyperhomocysteinemia-Induced Alzheimer-like Dementia.
Topics: Alzheimer Disease; Animals; Homocysteine; Hydroxyl Radical; Hyperhomocysteinemia; Mice; Optical Imaging; Risk Factors | 2023 |
Glycyrrhizic Acid Inhibits High-Mobility Group Box-1 and Homocysteine-Induced Vascular Dysfunction.
Topics: Acetylcholine; Animals; Atherosclerosis; Glycyrrhizic Acid; HMGB Proteins; Homocysteine; Hyperhomocysteinemia; Inflammation; Male; Rabbits | 2023 |
Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes.
Topics: Alzheimer Disease; Animals; Atorvastatin; Cognition; Cognitive Dysfunction; Dementia, Vascular; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Mice | 2023 |
Defective quality control autophagy in Hyperhomocysteinemia promotes ER stress and consequent neuronal apoptosis through proteotoxicity.
Topics: Animals; Apoptosis; Autophagy; Homocysteine; Hyperhomocysteinemia; Quality Control; Zebrafish | 2023 |
Development and Validation of a Novel Model for Predicting Coronary Heart Disease in Snoring Hypertensive Patients with Hyperhomocysteinemia.
Topics: Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Nomograms; Snoring | 2023 |
Melatonin Treatment Ameliorates Hyperhomocysteinemia-Induced Impairment of Erectile Function in a Rat Model.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caspase 3; Disease Models, Animal; Erectile Dysfunction; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malondialdehyde; Melatonin; NADPH Oxidases; Oxidative Stress; Penile Erection; Penis; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 2019 |
Associations Between Elevated Plasma Total Homocysteine Level and Risk of Thromboangiitis Obliterans in a Chinese Population: A Matched Case-Control Study.
Topics: Adult; Biomarkers; Case-Control Studies; China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Assessment; Risk Factors; Thromboangiitis Obliterans; Up-Regulation | 2020 |
Increased Carotid Intima-Media Thickness (IMT) in Hyperuricemic Individuals May Be Explained by Hyperhomocysteinemia Associated with Renal Dysfunction: a Cross-Sectional Study.
Topics: Carotid Arteries; Carotid Intima-Media Thickness; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hyperuricemia; Kidney Diseases; Male; Middle Aged; Risk Factors; Ultrasonography | 2019 |
Serum total homocysteine level in Iraqi woman with unexplained recurrent Miscarriage.
Topics: Abortion, Habitual; Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; ROC Curve; Sensitivity and Specificity; Vitamin B 12 | 2019 |
Homocysteine-methionine cycle is a metabolic sensor system controlling methylation-regulated pathological signaling.
Topics: Cytosol; Gene Regulatory Networks; Histones; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Protein Interaction Maps; Protein Transport | 2020 |
Homocysteine is an independent predictor of long-term cardiac mortality in patients with stable coronary artery disease in the era of statins.
Topics: Acute Coronary Syndrome; Aged; Arrhythmias, Cardiac; Cardiovascular Diseases; Cholesterol, LDL; Coronary Artery Disease; Coronary Stenosis; Female; Greece; Homocysteine; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Ischemic Stroke; Male; Middle Aged; Myocardial Revascularization; Prognosis; Proportional Hazards Models; Registries | 2020 |
Hyperhomocysteinemia induces vascular calcification by activating the transcription factor RUNX2 via Krüppel-like factor 4 up-regulation in mice.
Topics: Animals; Atherosclerosis; Core Binding Factor Alpha 1 Subunit; Female; Homocysteine; Hyperhomocysteinemia; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Phosphates; RNA, Small Interfering; Vascular Calcification | 2019 |
Low-dose alcohol ameliorated homocysteine-induced anxiety-related behavior via attenuating oxidative stress in mice.
Topics: Animals; Anxiety; Behavior, Animal; Central Nervous System Depressants; Elevated Plus Maze Test; Ethanol; Heme Oxygenase-1; Hippocampus; Homocysteine; Hyperhomocysteinemia; Inflammation; Interleukin-1beta; Male; Membrane Proteins; Mice; Open Field Test; Oxidative Stress; Superoxide Dismutase-1 | 2020 |
Hyperhomocysteinemia induced locked-in syndrome in a young adult due to folic acid deficiency.
Topics: Adolescent; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Locked-In Syndrome; Male; Vitamin B 12; Young Adult | 2021 |
Comment on 'The effects of isotretinoin therapy on serum homocysteine, folate and vitamin B12 levels in patients with acne': may retinoids be useful to treat hyperhomocysteinemia found in patients affected by hidradenitis suppurativa?
Topics: Acne Vulgaris; Folic Acid; Hidradenitis Suppurativa; Homocysteine; Humans; Hyperhomocysteinemia; Isotretinoin; Retinoids; Vitamin B 12 | 2020 |
Homocysteine accelerates atherosclerosis by inhibiting scavenger receptor class B member1 via DNMT3b/SP1 pathway.
Topics: Animals; Apolipoproteins E; Atherosclerosis; CD36 Antigens; Diet; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Down-Regulation; Foam Cells; HEK293 Cells; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Plaque, Atherosclerotic; Promoter Regions, Genetic; Protein Binding; Signal Transduction; Sp1 Transcription Factor; THP-1 Cells | 2020 |
IL‑37 expression is decreased in patients with hyperhomocysteinemia and protects cells from inflammatory injury by homocysteine.
Topics: Adult; Aged; Aged, 80 and over; Female; Gene Expression Regulation; Homocysteine; Humans; Hydro-Lyases; Hyperhomocysteinemia; Inflammation; Interleukin-1; Interleukin-1beta; Interleukin-6; Male; Middle Aged; RNA, Messenger; Tumor Necrosis Factor-alpha | 2020 |
Homocysteine levels and platelet reactivity in coronary artery disease patients treated with ticagrelor.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Biomarkers; Dual Anti-Platelet Therapy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticagrelor; Time Factors; Treatment Outcome | 2020 |
INFLUENCE OF CHRONIC HYPERHOMOCYSTEINEMIA ON METABOLISM OF SULFUR CONTAINING AMINO ACIDS IN THE RATS' HEART AND BRAIN ON THE BACKGROUND OF HYPERTHYREOSIS AND HYPOTHYREOSIS.
Topics: Amino Acids; Animals; Brain; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Myocardium; Sulfur | 2019 |
Chronic mild hyperhomocysteinemia induces anxiety-like symptoms, aversive memory deficits and hippocampus atrophy in adult rats: New insights into physiopathological mechanisms.
Topics: Adenosine Triphosphate; Animals; Anxiety; Atrophy; Avoidance Learning; Chronic Disease; DNA Damage; Electron Transport Complex IV; Hippocampus; Homocysteine; Hyperhomocysteinemia; Male; Memory Disorders; Open Field Test; Oxidative Stress; Rats; Rats, Wistar | 2020 |
Serum concentration of homocysteine in spontaneous feline chronic kidney disease.
Topics: Animals; Azotemia; Cat Diseases; Cats; Enzyme Assays; Female; Homocysteine; Hyperhomocysteinemia; Hypertension; Longitudinal Studies; Male; Proteinuria; Renal Insufficiency, Chronic | 2019 |
Homocysteine and Asymmetrical Dimethylarginine in Diabetic Rats Treated with Docosahexaenoic Acid-Loaded Zinc Oxide Nanoparticles.
Topics: Animals; Arginine; Cellulose; Diabetes Mellitus, Experimental; Docosahexaenoic Acids; Homocysteine; Hyperhomocysteinemia; Insulin; Insulin Resistance; Male; Metal Nanoparticles; Microscopy, Electron, Transmission; Nitric Oxide; Rats; Risk Factors; Zinc Oxide | 2020 |
Inhibiting MARSs reduces hyperhomocysteinemia-associated neural tube and congenital heart defects.
Topics: Animals; Female; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Male; Methionine-tRNA Ligase; Mice; Mice, Inbred C57BL; Neural Tube Defects; Rats; Rats, Sprague-Dawley; United States | 2020 |
Association Between Homocysteine and Vascular Calcification Incidence, Prevalence, and Progression in the MESA Cohort.
Topics: Aged; Aged, 80 and over; Biomarkers; Disease Progression; Female; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Prevalence; Prognosis; Prospective Studies; Risk Assessment; Risk Factors; Time Factors; United States; Up-Regulation; Vascular Calcification | 2020 |
Hyperhomocysteinemia accompany with metabolic syndrome increase the risk of left ventricular hypertrophy in rural Chinese.
Topics: Adult; Biomarkers; China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertrophy, Left Ventricular; Male; Metabolic Syndrome; Middle Aged; Prevalence; Risk Assessment; Risk Factors; Rural Health; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Associations of MTRR A66G polymorphism and promoter methylation with ischemic stroke in patients with hyperhomocysteinemia.
Topics: Aged; Case-Control Studies; DNA Methylation; Female; Ferredoxin-NADP Reductase; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Stroke; Logistic Models; Male; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Factors | 2020 |
Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging.
Topics: Aging; Animals; Autophagy; Cells, Cultured; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Male; Metalloporphyrins; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley | 2020 |
Hyperhomocysteinemia Associated with Multiple Organ Failure in Acute Pancreatitis Patients.
Topics: C-Reactive Protein; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Leukocyte Count; Logistic Models; Male; Middle Aged; Multiple Organ Failure; Multivariate Analysis; Pancreatitis; ROC Curve; Severity of Illness Index; Treatment Outcome | 2020 |
An unusually high plasma concentration of homocysteine resulting from a combination of so-called "secondary" etiologies.
Topics: Aged; Betaine; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Leucovorin; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2020 |
Effects of hyperhomocysteinemia on ischemic cerebral small vessel disease and analysis of inflammatory mechanisms.
Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Cerebral Small Vessel Diseases; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Male; Middle Aged; Risk Factors | 2021 |
Serum homocysteine and risk of dementia in Japan.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Dementia, Vascular; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors | 2020 |
A prospective cohort study of MTHFR C677T gene polymorphism and its influence on the therapeutic effect of homocysteine in stroke patients with hyperhomocysteinemia.
Topics: Adult; Aged; Alleles; Cohort Studies; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prospective Studies; Risk Factors; Stroke | 2020 |
No evidence for an association of plasma homocysteine levels and refractive error - Results from the population-based Gutenberg Health Study (GHS).
Topics: Adult; Aged; Female; Germany; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myopia; Prospective Studies; Refractive Errors; Risk Factors | 2020 |
Effect of High Homocysteine Level on the Severity of Coronary Heart Disease and Prognosis After Stent Implantation.
Topics: Aged; Aged, 80 and over; Biomarkers; Coronary Artery Disease; Drug-Eluting Stents; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Percutaneous Coronary Intervention; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome | 2020 |
Identifying gene-environment interactions on the efficacy of folic acid therapy for hyperhomocysteinemia based on prediction model.
Topics: Aged; Algorithms; Coronary Disease; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Machine Learning; Male; Middle Aged; Models, Theoretical; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Stroke; Treatment Failure; Treatment Outcome | 2020 |
Association between gene promoter methylation of the one-carbon metabolism pathway and serum folate among patients with hyperhomocysteinemia.
Topics: Carbon; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylation; Promoter Regions, Genetic | 2020 |
Hyperhomocysteinemia-Induced Oxidative Stress Exacerbates Cortical Traumatic Brain Injury Outcomes in Rats.
Topics: Animals; Anxiety; Behavior, Animal; Blood Coagulation; Blood-Brain Barrier; Brain Injuries, Traumatic; Cerebral Cortex; Homocysteine; Hyperhomocysteinemia; Inflammation; Intercellular Adhesion Molecule-1; Male; Methionine; Occludin; Oxidative Stress; Rats, Sprague-Dawley; Tyrosine; Zonula Occludens-1 Protein | 2021 |
Nicorandil reversed homocysteine-induced coronary microvascular dysfunction via regulating PI3K/Akt/eNOS pathway.
Topics: Animals; Cell Survival; Cells, Cultured; Chromones; Endothelial Cells; Homocysteine; Humans; Hyperhomocysteinemia; Hypoxia; Male; Mice; Microcirculation; Morpholines; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nicorandil; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Plant Lectins; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-akt; Ventricular Function, Left | 2020 |
Low doses of folic acid can reduce hyperhomocysteinemia-induced glomerular injury in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Drug Evaluation, Preclinical; Folic Acid; Homocysteine; Hyperhomocysteinemia; Hypertension; Kidney Cortex; Kidney Diseases; Male; Malondialdehyde; Membrane Proteins; NADPH Oxidase 2; NADPH Oxidase 4; Podocytes; Random Allocation; Rats, Inbred SHR; Superoxide Dismutase; Vitamin B Complex | 2020 |
Ocimum Sanctum Linn: A Potential Adjunct Therapy for Hyperhomocysteinemia-Induced Vascular Dementia.
Topics: Animals; Brain; Dementia, Vascular; Homocysteine; Hyperhomocysteinemia; Maze Learning; Molecular Docking Simulation; Nitric Oxide; Ocimum sanctum; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar | 2020 |
Distribution characteristics of circulating homocysteine and folate and related factors in agriculture, stock-raising and urban populations: a cross-sectional survey.
Topics: Agriculture; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2021 |
Hyperhomocysteinemia-Induced Oxidative Stress Aggravates Renal Damage in Hypertensive Rats.
Topics: Albuminuria; Animals; Blood Pressure; Creatinine; Glomerular Filtration Rate; Homocysteine; Hyperhomocysteinemia; Hypertension; Kidney; Malondialdehyde; Membrane Proteins; NADPH Oxidase 2; NADPH Oxidase 4; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Insufficiency; Superoxide Dismutase | 2020 |
Hyperhomocysteinemia in patients with acute porphyrias: A potentially dangerous metabolic crossroad?
Topics: Cystathionine beta-Synthase; Homocysteine; Humans; Hyperhomocysteinemia; Porphyria, Acute Intermittent; Vitamin B 12 | 2020 |
Prevalence and clinical demography of hyperhomocysteinemia in Han Chinese patients with schizophrenia.
Topics: Aged; Asian People; China; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Risk Factors; Schizophrenia | 2021 |
Cysteine is a better predictor of coronary artery disease than conventional homocysteine in high-risk subjects under preventive medication.
Topics: Adult; Aged; Biomarkers; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Portugal; Predictive Value of Tests; Prevalence; Primary Prevention; Prognosis; Retrospective Studies; Risk Assessment; Risk Factors; Secondary Prevention; Severity of Illness Index | 2020 |
Hyperhomocysteinemia is Associated with Inflammation, Bone Resorption, Vitamin B12 and Folate Deficiency and MTHFR C677T Polymorphism in Postmenopausal Women with Decreased Bone Mineral Density.
Topics: Bone Density; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osteitis; Osteoporosis, Postmenopausal; Oxidoreductases; Polymorphism, Genetic; Postmenopause; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Methylene tetrahydrofolate reductase C677T polymorphism in Korean livedoid vasculopathy patients.
Topics: Adolescent; Adult; Case-Control Studies; Eczema; Female; Genetic Association Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Point Mutation; Polymorphism, Single Nucleotide; Psoriasis; Republic of Korea; Retrospective Studies; Thrombophilia; Vasculitis; Young Adult | 2021 |
Homocysteine concentration and adenosine A
Topics: Aged; Cells, Cultured; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Leukocytes, Mononuclear; Male; Receptor, Adenosine A2A | 2020 |
Anti-Oxidant and Anti-Endothelial Dysfunctional Properties of Nano-Selenium in vitro and in vivo of Hyperhomocysteinemic Rats.
Topics: Animals; Antioxidants; Apoptosis; Biological Availability; Glutathione Peroxidase; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Hypertension; Male; Mitochondria; Nanoparticles; Oxidation-Reduction; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Selenium | 2020 |
Hydrogen Sulfide Alleviates Anxiety, Motor, and Cognitive Dysfunctions in Rats with Maternal Hyperhomocysteinemia via Mitigation of Oxidative Stress.
Topics: Animals; Anxiety; Cognitive Dysfunction; Cystathionine beta-Synthase; Female; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Oxidative Stress; Pregnancy; Pregnancy Complications; Rats; Reactive Oxygen Species; Treatment Outcome | 2020 |
Hyperhomocysteinemia and Low Folate and Vitamin B12 Are Associated with Vascular Dysfunction and Impaired Nitric Oxide Sensitivity in Morbidly Obese Patients.
Topics: Adult; Alcohol Drinking; Arterioles; Bariatric Surgery; Brachial Artery; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nitric Oxide; Nutritional Status; Obesity, Morbid; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Characteristics of the carotid plaque in hypertensive patients with hyperhomocysteinemia using multimode ultrasound.
Topics: Aged; Biomarkers; Blood Pressure; Carotid Intima-Media Thickness; Carotid Stenosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Plaque, Atherosclerotic; Predictive Value of Tests; Prognosis; Risk Factors; Severity of Illness Index | 2020 |
Hierarchical Surface Architecture of Hemodialysis Membranes for Eliminating Homocysteine Based on the Multifunctional Role of Pyridoxal 5'-phosphate.
Topics: Cell Adhesion; Cell Proliferation; Coated Materials, Biocompatible; Glycerol; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hydrophobic and Hydrophilic Interactions; Hyperhomocysteinemia; Membranes, Artificial; Models, Biological; Muramidase; Polymers; Porosity; Pyridoxal Phosphate; Renal Dialysis; Serum Albumin, Bovine; Sulfones; Surface Properties; Tromethamine | 2020 |
Role of hyperhomocysteine, thyroid dysfunction and their interaction in ischemic stroke patients with non-valvular atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypothyroidism; Ischemic Stroke; Magnetic Resonance Imaging; Male; Middle Aged; Prospective Studies; Risk Factors; Sex Factors; Thyroid Gland; Thyrotropin | 2020 |
Hyperhomocysteinemia: an instigating factor for periodontal disease.
Topics: Animals; Cystathionine beta-Synthase; Disease Models, Animal; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mice; Mice, Transgenic; Oxidative Stress; Periodontitis; Periodontium | 2021 |
Effect of Methionine Diet on Time-Related Metabolic and Histopathological Changes of Rat Hippocampus in the Model of Global Brain Ischemia.
Topics: Animals; Brain Ischemia; Diet; Hippocampus; Homocysteine; Hyperhomocysteinemia; Magnetic Resonance Spectroscopy; Male; Methionine; Rats; Rats, Wistar | 2020 |
Telomere length and mtDNA copy number in human cystathionine β-synthase deficiency.
Topics: Adolescent; Adult; Child; Child, Preschool; Cystathionine beta-Synthase; DNA Copy Number Variations; DNA, Mitochondrial; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Middle Aged; Telomere; Telomere Shortening; Young Adult | 2020 |
The Association between Hyperhomocysteinemia and Thoracoabdominal Aortic Aneurysms in Chinese Population.
Topics: Aortic Aneurysm, Thoracic; Asian People; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Odds Ratio; Risk Factors | 2020 |
Which one, gastric parietal cell antibody positivity or hyperhomocysteinemia, is a better biomarker to predict oral mucosal disease patients with vitamin B12 deficiency?
Topics: Biomarkers; Case-Control Studies; Folic Acid; Folic Acid Deficiency; Glossitis; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Parietal Cells, Gastric; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Prevalence of hyperhomocysteinaemia, selected determinants and relation to hypertension severity in Northern-Nigerian hypertensives: the ABU homocysteine survey.
Topics: Adult; Blood Pressure; Blood Pressure Determination; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Nigeria; Prevalence; Risk Factors; Surveys and Questionnaires | 2020 |
The association between plasma homocysteine level and metabolic syndrome. A record-based study of Saudi patients attending King Abdulaziz Medical City in Riyadh, Saudi Arabia.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Comorbidity; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolic Syndrome; Middle Aged; Prevalence; Saudi Arabia; Tertiary Care Centers; Young Adult | 2020 |
Homocysteine induces oxidative stress and ferroptosis of nucleus pulposus via enhancing methylation of GPX4.
Topics: Animals; Ferroptosis; Homocysteine; Hyperhomocysteinemia; Methylation; Mice; Nucleus Pulposus; Oxidative Stress; Rats | 2020 |
HMGB1 mediates homocysteine-induced endothelial cells pyroptosis via cathepsin V-dependent pathway.
Topics: Aged; Animals; Caspase 1; Cathepsins; Cell Line; Cysteine Endopeptidases; Endothelium, Vascular; Female; HMGB1 Protein; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Middle Aged; Phosphate-Binding Proteins; Pyroptosis; Thoracic Arteries | 2020 |
Proteinuria as a presenting sign of combined methylmalonic acidemia and homocysteinemia: case report.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Base Sequence; Carnitine; Child, Preschool; DNA; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Proteinuria | 2020 |
Homocysteinemia is Associated with the Presence of Microbleeds in Cognitively Impaired Patients.
Topics: Aged; Aged, 80 and over; Biomarkers; Cerebral Hemorrhage; Cognition; Cognitive Dysfunction; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Risk Factors; Seoul | 2020 |
Acute exogenous intoxications and homocysteine.
Topics: Adolescent; Adult; Aged; Alcohols; Female; Heroin; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Middle Aged; Oxidative Stress; Poisoning; Prospective Studies; Young Adult | 2020 |
Very High Plasma Homocysteine without Malnutrition or Inherited Disorder.
Topics: Dairy Products; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nitrous Oxide; Young Adult | 2020 |
N-Methyl-D-aspartate receptor activation, novel mechanism of homocysteine-induced blood-retinal barrier dysfunction.
Topics: Animals; Blood-Retinal Barrier; Disease Models, Animal; Endothelial Cells; Homocysteine; Humans; Hyperhomocysteinemia; Mice, Inbred C57BL; Mice, Transgenic; Receptors, N-Methyl-D-Aspartate; Retina | 2021 |
Study on Maternal SNPs of MTHFR Gene and HCY Level Related to Congenital Heart Diseases.
Topics: Adult; Case-Control Studies; Child; Female; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Mutation; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Surveys and Questionnaires; Young Adult | 2021 |
The effect of folate and VitB
Topics: Aged; Cognition; Cognitive Dysfunction; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Treatment Outcome; Vitamin B 12 | 2020 |
No causal association between plasma homocysteine levels and atrial fibrillation: A Mendelian randomization study.
Topics: Atrial Fibrillation; Biomarkers; Genetic Predisposition to Disease; Genome-Wide Association Study; Homocysteine; Humans; Hyperhomocysteinemia; Mendelian Randomization Analysis; Meta-Analysis as Topic; Phenotype; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors | 2021 |
Hydrogen sulfide attenuates hyperhomocysteinemia-induced blood-brain barrier permeability by inhibiting MMP-9.
Topics: Animals; Blood-Brain Barrier; Coloring Agents; Evans Blue; Fluorescein; Gelatin; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Permeability; RNA, Messenger; Sodium; Water | 2022 |
Epigallocatechin Gallate Reduces Homocysteine-Caused Oxidative Damages through Modulation SIRT1/AMPK Pathway in Endothelial Cells.
Topics: AMP-Activated Protein Kinases; Antioxidants; Apoptosis; Catechin; Dose-Response Relationship, Drug; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; NADPH Oxidases; Oxidative Stress; Phytotherapy; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Sirtuin 1; Tea | 2021 |
Implementation of programmed cell death in circulating neutrophils and its special characteristics in experimentally induced hyperhomocysteinemia in a setting of thyroid dysfunction.
Topics: Animals; Apoptosis; Homocysteine; Hyperhomocysteinemia; Neutrophils; Rats; Reactive Oxygen Species | 2020 |
Relationship between plasma homocysteine and blood pressure in hypertensive Northern-Nigerians.
Topics: Biomarkers; Blood Pressure; Blood Pressure Determination; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Risk Factors | 2020 |
Hyperhomocysteinemia and Dementia Associated With Severe Cortical Atrophy, but No Amyloid Burden.
Topics: Aged; Alzheimer Disease; Atrophy; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 2022 |
Associations between hyperhomocysteinemia and the presence and severity of acute coronary syndrome in young adults ≤ 35 years of age.
Topics: Acute Coronary Syndrome; Adolescent; Adult; Age of Onset; Beijing; Biomarkers; Coronary Angiography; Coronary Stenosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Up-Regulation; Young Adult | 2021 |
POSITIVE EFFECT OF BETAINE-ARGININE SUPPLEMENT ON IMPROVED HYPERHOMOCYSTEINEMIA TREATMENT IN MARRIED COUPLES WITH REPRODUCTIVE DISORDERS.
Topics: Arginine; Betaine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12 | 2020 |
Association between vitamin D deficiency and serum Homocysteine levels and its relationship with coronary artery disease.
Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin D; Vitamin D Deficiency | 2021 |
Association of High Serum Homocysteine Levels and Severe Chronic Venous Disease.
Topics: Age Factors; Aged; Biomarkers; Chronic Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Sex Factors; Up-Regulation; Vascular Diseases; Veins | 2021 |
Hyperhomocysteinemia and its relations to conventional risk factors for cardiovascular diseases in adult Nigerians: the REMAH study.
Topics: Adolescent; Adult; Aged; Biomarkers; Black People; Blood Pressure; Cardiovascular Diseases; Cholesterol, HDL; Dyslipidemias; Heart Disease Risk Factors; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Nigeria; Prevalence; Risk Assessment; Young Adult | 2021 |
Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson's disease.
Topics: Aged; Bacteria; Case-Control Studies; Databases, Genetic; Dysbiosis; Folic Acid; Folic Acid Deficiency; Gastrointestinal Microbiome; Homocysteine; Humans; Hyperhomocysteinemia; Intestines; Male; Metabolome; Metabolomics; Metagenome; Metagenomics; Middle Aged; Mucins; Parkinson Disease; Polysaccharides; Severity of Illness Index | 2021 |
Hydrogen sulphide reduces hyperhomocysteinaemia-induced endothelial ER stress by sulfhydrating protein disulphide isomerase to attenuate atherosclerosis.
Topics: Animals; Atherosclerosis; Cell Line; Disease Models, Animal; Endoplasmic Reticulum Stress; Endothelial Cells; HEK293 Cells; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Mice; Mice, Knockout, ApoE; Protein Disulfide-Isomerases; Up-Regulation | 2021 |
Cardiovascular manifestations of intermediate and major hyperhomocysteinemia due to vitamin B12 and folate deficiency and/or inherited disorders of one-carbon metabolism: a 3.5-year retrospective cross-sectional study of consecutive patients.
Topics: Adult; Cardiovascular Diseases; Child, Preschool; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Middle Aged; Retrospective Studies; Vitamin B 12 | 2021 |
Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents.
Topics: Animals; Cerebellum; Corpus Striatum; Cytokines; Electron Transport Complex IV; Energy Metabolism; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Male; Mitochondria; Oxidative Stress; Rats; Rats, Wistar | 2021 |
Gender differences in risk factors for high plasma homocysteine levels based on a retrospective checkup cohort using a generalized estimating equation analysis.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; China; Factor Analysis, Statistical; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Models, Biological; Prevalence; Retrospective Studies; Risk Factors; Sex Characteristics; Young Adult | 2021 |
Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Topics: Acetylgalactosamine; Adult; Arginine; Cystathionine beta-Synthase; Female; Folic Acid; Heme; Homeostasis; Homocysteine; Homocystinuria; Humans; Hydroxymethylbilane Synthase; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Porphyria, Acute Intermittent; Pyridoxal Phosphate; Pyrrolidines; Young Adult | 2021 |
The association between homocysteine levels and cardiovascular disease risk among middle-aged and elderly adults in Taiwan.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Female; Heart Disease Risk Factors; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Risk Assessment; Taiwan; Time Factors; Up-Regulation | 2021 |
Hyperhomocysteinemia-related serum metabolome alterations not normalized by short-term folic acid treatment.
Topics: Adolescent; Adult; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Metabolome; Vitamin B 12; Young Adult | 2021 |
Homocysteine Is Associated With Future Venous Thromboembolism in 2 Prospective Cohorts of Women.
Topics: Adult; Age Factors; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Middle Aged; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Sex Factors; Time Factors; United States; Venous Thromboembolism | 2021 |
Severe homocysteinemia in two givosiran-treated porphyria patients: is free heme deficiency the culprit?
Topics: 5-Aminolevulinate Synthetase; Acetylgalactosamine; Adult; Arginine; Colitis; Colon, Sigmoid; Controlled Clinical Trials as Topic; Drug Hypersensitivity; Female; Fibrosis; Heme; Hepatocytes; High-Throughput Nucleotide Sequencing; Homocysteine; Humans; Hydroxymethylbilane Synthase; Hyperhomocysteinemia; Male; Models, Biological; Pancreatitis; Porphyria, Acute Intermittent; Pyrrolidines | 2021 |
Methionine Diet Evoked Hyperhomocysteinemia Causes Hippocampal Alterations, Metabolomics Plasma Changes and Behavioral Pattern in Wild Type Rats.
Topics: Animals; Behavior, Animal; Hippocampus; Homocysteine; Hyperhomocysteinemia; In Situ Nick-End Labeling; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methionine; Rats, Wistar; Staining and Labeling | 2021 |
A study of hyperhomocysteinemia in cerebral venous sinus thrombosis.
Topics: Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; India; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Sinus Thrombosis, Intracranial; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Simvastatin increases circulating endothelial progenitor cells and inhibits the formation of intracranial aneurysms in rats with diet-induced hyperhomocysteinemia.
Topics: Animals; Biomarkers; Disease Models, Animal; Endothelial Progenitor Cells; Endothelium, Vascular; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Intracranial Aneurysm; Male; Rats; Rats, Sprague-Dawley; Simvastatin; Vascular Remodeling | 2021 |
Mild hyperhomocysteinemia induces blood-brain barrier dysfunction but not neuroinflammation in the cerebral cortex and hippocampus of wild-type mice.
Topics: Animals; Blood-Brain Barrier; Cerebral Cortex; Cytokines; Hippocampus; Homocysteine; Hyperhomocysteinemia; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Signal Transduction; STAT3 Transcription Factor | 2021 |
Higher serum homocysteine level and frequency of hyperhomocysteinemia in carcinoembryonic antigen-positive or squamous cell carcinoma-antigen-positive oral leukoplakia patients.
Topics: Antigens, Neoplasm; Autoantibodies; Carcinoembryonic Antigen; Erythrocyte Indices; Folic Acid; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Leukoplakia, Oral; Parietal Cells, Gastric; Serpins; Vitamin B 12 | 2021 |
Hyperhomocysteinemia in patients with acute porphyrias: a possible effect of ALAS1 modulation by siRNAm therapy and its control by vitamin supplementation.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Porphyria, Acute Intermittent; Vitamin B 12; Vitamins | 2021 |
Elevated Plasma Homocysteine Level Associated with Further Left Ventricular Structure and Function Damages in Type 2 Diabetic Patients: A Three-Dimensional Speckle Tracking Echocardiography Study.
Topics: Aged; Diabetes Mellitus, Type 2; Echocardiography; Female; Heart Ventricles; Homocysteine; Humans; Hyperhomocysteinemia; Imaging, Three-Dimensional; Male; Middle Aged; Ventricular Dysfunction, Left; Ventricular Remodeling | 2021 |
Analysis of the association and predictive value of hyperhomocysteinaemia for obstructive coronary artery disease.
Topics: China; Coronary Angiography; Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Retrospective Studies; Risk Factors | 2021 |
Lower expression of Hsa_circRNA_102682 in diabetic hyperhomocysteinemia negatively related to creatinemia is associated with TGF-β and CTGF.
Topics: Connective Tissue Growth Factor; Creatinine; Diabetic Nephropathies; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; RNA, Circular; ROC Curve; Transforming Growth Factor beta | 2021 |
Mild Hyperhomocysteinemia Causes Anxiety-like Behavior and Brain Hyperactivity in Rodents: Are ATPase and Excitotoxicity by NMDA Receptor Overstimulation Involved in this Effect?
Topics: Animals; Anxiety; Brain; Dizocilpine Maleate; Glutamate-Ammonia Ligase; Glutamic Acid; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Rodentia; Sodium-Potassium-Exchanging ATPase; Sucrose | 2022 |
The prevalence, relative risk factors and MTHFR C677T genotype of H type hypertension of the elderly hypertensives in Shanghai, China: a cross-section study : Prevalence of H type hypertension.
Topics: Adult; Aged; Aged, 80 and over; China; Cross-Sectional Studies; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Prevalence; Risk Factors | 2021 |
[Homocysteine and markers of endothelial dysfunction in multiple sclerosis].
Topics: Biomarkers; Homocysteine; Humans; Hyperhomocysteinemia; Male; Multiple Sclerosis; von Willebrand Factor | 2021 |
Insufficient S-Sulfhydration of Methylenetetrahydrofolate Reductase Contributes to the Progress of Hyperhomocysteinemia.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidation-Reduction; Vitamin B 12 | 2022 |
EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways.
Topics: Antioxidants; Apoptosis; Atherosclerosis; Catechin; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Mitochondria; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Signal Transduction | 2017 |
Homocysteine Induces Hepatic Steatosis Involving ER Stress Response in High Methionine Diet-Fed Mice.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cells, Cultured; Endoplasmic Reticulum Stress; Gene Expression Regulation; Hepatocytes; Homocysteine; Hyperhomocysteinemia; Lipogenesis; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Organ Size; Phenylbutyrates; Random Allocation; Tunicamycin | 2017 |
The Prevalence of Hypertension Accompanied by High Homocysteine and its Risk Factors in a Rural Population: A Cross-Sectional Study from Northeast China.
Topics: Adult; Aged; China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Prevalence; Risk Factors; Rural Population | 2017 |
Hydrogen sulfide attenuates homocysteine-induced cognitive deficits and neurochemical alterations by improving endogenous hydrogen sulfide levels.
Topics: Animals; Cerebral Cortex; Cognition; Cognitive Dysfunction; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dopamine; Epinephrine; Gene Expression; Hippocampus; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Injections, Subcutaneous; Locomotion; Male; Maze Learning; Monoamine Oxidase; Norepinephrine; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Serotonin; Sulfides | 2017 |
Correlation of hippocampal atrophy with hyperhomocysteinemia in hemodialysis patients: An exploratory pilot study.
Topics: Age Factors; Aged; Ankle Brachial Index; Atherosclerosis; Atrophy; Body Mass Index; Cross-Sectional Studies; Female; Hippocampus; Homocysteine; Humans; Hyperhomocysteinemia; Hypoalbuminemia; Magnetic Resonance Imaging; Male; Organ Size; Outpatients; Pilot Projects; Pulse Wave Analysis; Regression Analysis; Renal Dialysis | 2017 |
An Analysis of Transcobalamin II Gene Polymorphisms and Serum Levels of Homocysteine, Folate and Vitamin B12 in Chinese Patients with Crohn's Disease.
Topics: Adult; Asian People; Case-Control Studies; Crohn Disease; Female; Folic Acid; Genetic Association Studies; Haplotypes; Homocysteine; Humans; Hyperhomocysteinemia; Male; Polymorphism, Single Nucleotide; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2017 |
Role of osteocytes in mediating bone mineralization during hyperhomocysteinemia.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Biomarkers; Biomechanical Phenomena; Calcification, Physiologic; Caspase 3; Extracellular Matrix Proteins; Female; Gene Expression Regulation; Glycoproteins; Homocysteine; Hyperhomocysteinemia; Intercellular Signaling Peptides and Proteins; Mice; Osteocalcin; Osteocytes; RNA, Messenger | 2017 |
[Age-related changes in biogenic amine content and oxidative stress profile in the rat hypothalamus in hyperhomocysteinemia].
Topics: Aging; Animals; Biogenic Amines; Female; Gonadotropin-Releasing Hormone; Homocysteine; Hyperhomocysteinemia; Hypothalamus; Oxidative Stress; Rats; Rats, Wistar | 2016 |
Correlation between plasma homocysteine levels and craving in alcohol dependent stabilized patients.
Topics: Alcoholism; Craving; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Psychiatric Status Rating Scales; Severity of Illness Index | 2018 |
Hyperhomocysteinemia as a Metabolic Risk Factor for Glucose Intolerance Among High-Risk Groups of Chinese Adults.
Topics: Adult; Asian People; Female; Glucose Intolerance; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Risk Factors | 2017 |
[A new link between high homocysteine levels, cancers and neurodegenerative diseases].
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Methionine; Neoplasms; Neurodegenerative Diseases; Risk Factors | 2017 |
l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia.
Topics: Animals; Aorta, Thoracic; Cathepsins; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; THP-1 Cells; Vascular Diseases | 2018 |
Expression levels of atherosclerosis-associated miR-143 and miR-145 in the plasma of patients with hyperhomocysteinaemia.
Topics: Adult; Area Under Curve; Carotid Artery Diseases; Case-Control Studies; Circulating MicroRNA; Female; Genetic Markers; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; MicroRNAs; Middle Aged; Plaque, Atherosclerotic; Predictive Value of Tests; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; ROC Curve; Ultrasonography | 2017 |
Elevated homocysteine increases the risk of left atrial/left atrial appendage thrombus in non-valvular atrial fibrillation with low CHA2DS2-VASc score.
Topics: Aged; Atrial Appendage; Atrial Fibrillation; Biomarkers; Cross-Sectional Studies; Echocardiography, Transesophageal; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Registries; Risk Assessment; Risk Factors; Thrombosis; Up-Regulation | 2018 |
Epidemiological characteristics of hyperhomocysteinemia and H-type hypertension in the elderly in Beijing, China.
Topics: Aged; Beijing; China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Longitudinal Studies; Male; Middle Aged; Prevalence; Retrospective Studies; Risk Factors; Rural Health; Urban Health | 2017 |
Hyperhomocysteinaemia is an independent risk factor for peripheral arterial disease in a Chinese Han population.
Topics: Aged; Ankle Brachial Index; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Peripheral Arterial Disease; Prevalence; Risk Assessment; Risk Factors | 2017 |
The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations.
Topics: Abortion, Habitual; Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Pregnancy; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2017 |
Plasma homocysteine levels associated with a corrected QT interval.
Topics: Action Potentials; Adult; Aged; Arrhythmias, Cardiac; Biomarkers; China; Electrocardiography; Female; Heart Conduction System; Heart Rate; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Predictive Value of Tests; Risk Factors; Time Factors | 2017 |
An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Sequence; Cells, Cultured; Exons; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylation; Models, Molecular; Pregnancy; Pregnancy Complications; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Deletion; Spinal Dysraphism; Young Adult | 2017 |
CYLD Deubiquitinates Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Contributing to Adventitial Remodeling.
Topics: Adventitia; Animals; Aortic Aneurysm, Abdominal; Calcium Phosphates; Cell Movement; Cell Transdifferentiation; Chemokine CCL2; Chlorocebus aethiops; COS Cells; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Stability; Extracellular Matrix; Genotype; Half-Life; HEK293 Cells; Homocysteine; Humans; Hyperhomocysteinemia; Interleukin-6; Male; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; NADPH Oxidase 4; NADPH Oxidases; Phenotype; Proteolysis; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA Interference; Signal Transduction; Time Factors; Transfection; Transforming Growth Factor beta1; Ubiquitin Thiolesterase; Ubiquitination; Vascular Remodeling | 2017 |
[Metabolic changes in pulmonary mitochondria of rats with experimental hyperhomocysteinemia].
Topics: Animals; Enzyme Inhibitors; Homocysteine; Humans; Hyperhomocysteinemia; L-Lactate Dehydrogenase; Lung; Male; Methionine; Mitochondria; Mitochondrial Proton-Translocating ATPases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Phosphorylation; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Succinate Dehydrogenase; Superoxide Dismutase | 2017 |
A Prospective Study of Homocysteine and its relation to Body Mass Index and Lipid Profile in School Children.
Topics: Adolescent; Body Mass Index; Child; Child, Preschool; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; India; Lipids; Male; Overweight; Pediatric Obesity; Prospective Studies; Risk Factors; Students | 2017 |
Comparison of oxidative stress biomarkers in hypertensive patients with or without hyperhomocysteinemia.
Topics: Aged; Antioxidants; Biomarkers; Catalase; Dinoprost; Female; Glutathione Peroxidase; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Oxidative Stress; Peroxides; Risk Factors; Superoxide Dismutase | 2018 |
Relationship between homocysteine and hypertension: New data add to the debate.
Topics: Adult; Blood Pressure; Causality; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension | 2017 |
Hyperhomocysteinemia as a Risk Factor for Saccular Intracranial Aneurysm: A Cohort Study in a Chinese Han Population.
Topics: Adult; Aged; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Intracranial Aneurysm; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Prospective Studies; Protective Factors; Risk Factors; Up-Regulation; Vitamin B 12 | 2017 |
No association between elevated homocysteine levels and carotid atherosclerosis in a rural population in China.
Topics: Aged; Biomarkers; Carotid Artery Diseases; China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Assessment; Risk Factors; Rural Health; Up-Regulation | 2016 |
Interplay between 3'-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke.
Topics: 3' Untranslated Regions; Aged; Brain Ischemia; Case-Control Studies; Female; Folic Acid; Gene Expression; Gene-Environment Interaction; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; Stroke | 2017 |
Homocysteine concentrations in the cognitive progression of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition; Disease Progression; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Mental Status and Dementia Tests; Neuropsychological Tests; Nutrition Assessment; Nutritional Status; Surveys and Questionnaires; Time Factors; Up-Regulation; Vitamin B 12 | 2017 |
Decreased Homocysteine Trans-Sulfuration in Hypertension With Hyperhomocysteinemia: Relationship With Insulin Resistance.
Topics: Blood Glucose; Case-Control Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin Resistance; Male; Middle Aged; Prognosis; Risk Factors; Sulfur | 2018 |
Vitamin Status and the Development of Postoperative Cognitive Decline in Elderly Surgical Oncologic Patients.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Preoperative Period; Vitamin B 12 | 2018 |
Structural changes of fibrinogen molecule mediated by the N-homocysteinylation reaction.
Topics: Electrophoresis, Capillary; Electrophoresis, Gel, Two-Dimensional; Fibrinogen; Homocysteine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Hyperhomocysteinemia; Isoelectric Focusing | 2018 |
Neopterin as an Effect Modifier of the Cardiovascular Risk Predicted by Total Homocysteine: A Prospective 2-Cohort Study.
Topics: Aged; Angina, Stable; Biomarkers; C-Reactive Protein; Coronary Angiography; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation Mediators; Kaplan-Meier Estimate; Linear Models; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Neopterin; Norway; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Up-Regulation | 2017 |
Prevalence and clinical-demographic correlates of hyperhomocysteinemia in inpatients with bipolar disorder in a Han Chinese population.
Topics: Adult; Bipolar Disorder; China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inpatients; Male; Middle Aged; Prevalence | 2018 |
Folate: a possible role in erectile dysfunction?
Topics: Adult; Case-Control Studies; Erectile Dysfunction; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Severity of Illness Index; Surveys and Questionnaires; Ultrasonography; Vitamin B 12 | 2018 |
Hyperhomocysteinemia-induced autophagy and apoptosis with downregulation of hairy enhancer of split 1/5 in cortical neurons in mice.
Topics: Animals; Apoptosis; Autophagy; Basic Helix-Loop-Helix Transcription Factors; Down-Regulation; Frontal Lobe; Homocysteine; Hyperhomocysteinemia; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Microscopy, Electron, Transmission; Neurons; Repressor Proteins; Transcription Factor HES-1 | 2017 |
Impact of hyperhomocysteinemia on insulin resistance in patients with H-type hypertension.
Topics: Adult; Blood Pressure; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin Resistance; Male; Middle Aged | 2018 |
Relationship between serum homocysteine levels and structural-functional carotid arterial abnormalities in inactive Behçet's disease.
Topics: Adult; Behcet Syndrome; Carotid Arteries; Carotid Intima-Media Thickness; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vasculitis | 2018 |
Chronic Mild Hyperhomocysteinemia Alters Inflammatory and Oxidative/Nitrative Status and Causes Protein/DNA Damage, as well as Ultrastructural Changes in Cerebral Cortex: Is Acetylsalicylic Acid Neuroprotective?
Topics: Acetylcholinesterase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalase; Cerebral Cortex; Comet Assay; Cytokines; Dendritic Spines; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Homocysteine; Hyperhomocysteinemia; Male; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2018 |
Total homocysteine is positively correlated with body mass index, waist-to-hip ratio, and fat mass among overweight reproductive women: A cross-sectional study.
Topics: Adolescent; Adult; Body Composition; Body Mass Index; Chromatography, Liquid; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Jordan; Middle Aged; Obesity; Overweight; Prevalence; Tandem Mass Spectrometry; Waist-Hip Ratio; Young Adult | 2017 |
Acute exercise alters homocysteine plasma concentration in an intensity-dependent manner due increased methyl flux in liver of rats.
Topics: Animals; Body Weight; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine Adenosyltransferase; Methylation; Physical Conditioning, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Swimming | 2018 |
Neuro-fuzzy model of homocysteine metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Asian People; Chromatography, High Pressure Liquid; Female; Ferredoxin-NADP Reductase; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Models, Theoretical; Polymorphism, Single Nucleotide; Thymidylate Synthase | 2017 |
Inverse association between plasma homocysteine concentrations and type 2 diabetes mellitus among a middle-aged and elderly Chinese population.
Topics: Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Biomarkers; Blood Glucose; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Assessment; Risk Factors | 2018 |
Association of elevated homocysteine levels and Methylenetetrahydrofolate reductase (MTHFR) 1298 A > C polymorphism with Vitiligo susceptibility in Gujarat.
Topics: Adolescent; Adult; Case-Control Studies; Child; Computer Simulation; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Vitamin B 12; Vitiligo; Young Adult | 2018 |
Genetic variants of the folate metabolic system and mild hyperhomocysteinemia may affect ADHD associated behavioral problems.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Attention Deficit Disorder with Hyperactivity; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Child; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Variation; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Pilot Projects; Problem Behavior; Replication Protein C; Signal Transduction | 2018 |
Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Chondrocytes; Cyclooxygenase 2; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinase 13; Mice; Mitochondria; Osteoarthritis; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Protein Kinases; Signal Transduction; Sirtuin 1 | 2018 |
Identification of vitamin B12 deficiency in vegetarian Indians.
Topics: Adult; Biomarkers; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Sample Size; Vegetarians; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2018 |
Expression Profiles of Six Atherosclerosis-Associated microRNAs That Cluster in Patients with Hyperhomocysteinemia: A Clinical Study.
Topics: Adult; Atherosclerosis; Biomarkers; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; MicroRNAs; Middle Aged; ROC Curve; Transcriptome; Up-Regulation | 2018 |
Association of homocysteine and smoking with cerebral microemboli in patients with mechanical heart valves: a transcranial Doppler study.
Topics: Aged; Biomarkers; Female; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Embolism; Male; Middle Aged; Predictive Value of Tests; Registries; Risk Assessment; Risk Factors; Smoking; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial; Up-Regulation | 2017 |
Vitamin B complex mitigates cardiac dysfunction in high-methionine diet-induced hyperhomocysteinemia.
Topics: Animals; Catalase; Diet; Glutathione; Heart; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Vitamin B Complex | 2018 |
Topics: Atherosclerosis; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Melatonin; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 | 2018 |
Association of prehypertension and hyperhomocysteinemia with subclinical atherosclerosis in asymptomatic Chinese: a cross-sectional study.
Topics: Adult; Atherosclerosis; Biomarkers; Blood Glucose; Blood Pressure; Carotid Intima-Media Thickness; China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prehypertension; Risk Factors | 2018 |
Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.
Topics: Alzheimer Disease; Animals; Brain; Cell Line, Tumor; Cyclin-Dependent Kinase 5; Disease Models, Animal; Glycogen Synthase Kinase 3; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Transgenic; Neurofibrillary Tangles; Phosphorylation; Protein Aggregation, Pathological; Protein Phosphatase 2; tau Proteins; Tauopathies | 2018 |
Exercise Mitigates Alcohol Induced Endoplasmic Reticulum Stress Mediated Cognitive Impairment through ATF6-Herp Signaling.
Topics: Activating Transcription Factor 6; Analysis of Variance; Animals; Behavior, Animal; Blood Pressure; Blood-Brain Barrier; Capillary Permeability; Cerebrovascular Circulation; Cognitive Dysfunction; Endoplasmic Reticulum Stress; Epigenesis, Genetic; Ethanol; Exercise Test; Exercise Therapy; Homocysteine; Hyperhomocysteinemia; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Animal; Normal Distribution; Oxidative Stress; Physical Conditioning, Animal | 2018 |
Homocysteine is the confounding factor of metabolic syndrome-confirmed by siMS score.
Topics: Adult; Age Factors; Aged; Biomarkers; Blood Glucose; C-Reactive Protein; Confounding Factors, Epidemiologic; Cross-Sectional Studies; Decision Support Techniques; Dyslipidemias; Female; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation Mediators; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Middle Aged; Obesity, Abdominal; Predictive Value of Tests; Risk Factors; Up-Regulation; Uric Acid | 2018 |
COMMERCIAL EXTRACT FROM ARONIA AS A MODULATOR OF ADHESIVE PROPERTIES OF FIBRINOGEN TREATED WITH HOMOCYSTEINE AND ITS THIOLACTONE IN VITRO.
Topics: Blood Platelets; Fibrinogen; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Photinia; Plant Extracts; Platelet Adhesiveness; Polyphenols | 2016 |
Which Ischemic Stroke Subtype Is Associated with Hyperhomocysteinemia?
Topics: Adult; Biomarkers; Brain Ischemia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Risk Factors; Stroke | 2018 |
Metabolic distress in lipid & one carbon metabolic pathway through low vitamin B-12: a population based study from North India.
Topics: Adult; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cross-Sectional Studies; Dyslipidemias; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Obesity; Triglycerides; Vitamin B 12; Vitamin B 12 Deficiency; Waist Circumference | 2018 |
[HYPERTENSION OF PREGNANCY ASSOCIATED WITH HYPERGOMOCYSTEINEMIA OF THE FIRST TRIMESTER OF PREGNANCY].
Topics: Adult; Eclampsia; Female; HELLP Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Pregnancy-Induced; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Prognosis; Prospective Studies | 2018 |
Significantly higher frequencies of hemoglobin, iron, vitamin B12, and folic acid deficiencies and of hyperhomocysteinemia in patients with Behcet's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia; Behcet Syndrome; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2018 |
Association of hyperhomocysteinemia with genetic variants in key enzymes of homocysteine metabolism and methotrexate toxicity in rheumatoid arthritis patients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Thymidylate Synthase; Tunisia; Vitamin B 12 | 2018 |
Elevated plasma homocysteine levels are associated with disability progression in patients with multiple sclerosis.
Topics: Adult; Disability Evaluation; Disease Progression; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multiple Sclerosis; Platelet Endothelial Cell Adhesion Molecule-1; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2018 |
Hyperhomocysteinemia in polycystic ovary syndrome: decreased betaine-homocysteine methyltransferase and cystathionine β-synthase-mediated homocysteine metabolism.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Disease Models, Animal; Female; Homocysteine; Hyperhomocysteinemia; Liver; Polycystic Ovary Syndrome; Rats | 2018 |
Methylenetetrahydrofolate reductase C677T variant and hyperhomocysteinemia in subarachnoid hemorrhage patients from India.
Topics: Adult; Alleles; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Subarachnoid Hemorrhage | 2018 |
Increased homocysteine plasma levels in breast cancer patients of a Mexican population.
Topics: Adult; Aged; Breast Neoplasms; Case-Control Studies; Chromatography, High Pressure Liquid; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Mexico; Middle Aged; Neoplasm Staging; Population Surveillance; Risk Factors; Symptom Assessment | 2018 |
Homocysteine is Associated with Exaggerated Morning Blood Pressure Surge in Patients with Acute Ischemic Stroke.
Topics: Aged; Biomarkers; Blood Pressure; Brain Ischemia; Circadian Rhythm; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Risk Factors; Stroke; Time Factors | 2018 |
Effect of Homocysteine on the Differentiation of CD4
Topics: Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Colon; Cyclooxygenase 2; Disease Models, Animal; Folic Acid; Group IV Phospholipases A2; Homocysteine; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Mucous Membrane; Nuclear Receptor Subfamily 1, Group F, Member 3; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Th17 Cells; Treatment Outcome; Vitamin B Complex | 2018 |
Folate-dependent constructive effect of cirrhosis on hyperhomocysteinemia.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis | 2018 |
Association of Induced Hyperhomocysteinemia with Alzheimer's Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury.
Topics: Alzheimer Disease; Animals; Cerebral Cortex; Homocysteine; Hyperhomocysteinemia; Male; Nerve Degeneration; Rats; Rats, Wistar; Reperfusion Injury | 2018 |
The risk association of plasma total homocysteine with acute myocardial infarction is modified by serum vitamin A.
Topics: Angina, Stable; Biomarkers; Female; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Myocardial Infarction; Norway; Prognosis; Prospective Studies; Risk Assessment; Risk Factors; Vitamin A | 2018 |
A relation of serum homocysteine, uric acid and C-reactive protein level in patients with acute myocardial infarction.
Topics: Aged; Atherosclerosis; Biomarkers; C-Reactive Protein; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Lymphocytes; Male; Middle Aged; Myocardial Infarction; Neutrophils; Percutaneous Coronary Intervention; Uric Acid | 2018 |
Diet-induced hyperhomocysteinemia impairs vasodilation in 5/6-nephrectomized rats.
Topics: Acetylcholine; Animals; Diet; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Male; Methionine; Nephrectomy; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Vasodilation | 2018 |
Subclinical atherosclerosis and impaired cardiac autonomic control in pediatric patients with Vitamin B12 deficiency.
Topics: Adolescent; Atherosclerosis; Autonomic Nervous System; Biomarkers; Carotid Artery, Common; Carotid Intima-Media Thickness; Case-Control Studies; Child; Echocardiography; Female; Heart; Heart Rate; Homocysteine; Humans; Hyperhomocysteinemia; Male; Microscopy, Acoustic; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Nuclear factor erythroid 2-related factor 2 activation mediates hyperhomocysteinemia-associated lipolysis suppression in adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cytoplasm; Disease Models, Animal; Fatty Acids; Gene Knockdown Techniques; Glycerol; Homocysteine; Hyperhomocysteinemia; Lipolysis; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Triglycerides | 2018 |
The anxiolytic effects of atorvastatin and simvastatin on dietary-induced increase in homocysteine levels in rats.
Topics: Animals; Anti-Anxiety Agents; Anticholesteremic Agents; Anxiety Disorders; Atorvastatin; Behavior, Animal; Diet; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Simvastatin | 2019 |
Homocysteine-lowering gene therapy rescues signaling pathways in brain of mice with intermediate hyperhomocysteinemia.
Topics: Adenoviridae; Animals; Brain; Dyrk Kinases; Female; Gene Transfer Techniques; Genetic Therapy; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction | 2018 |
Homocysteine might increase the risk of recurrence in patients presenting with primary cerebral infarction.
Topics: Aged; Biomarkers; Cerebral Infarction; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Recurrence; Risk Factors | 2019 |
Association of vitamin B12 mediated hyperhomocysteinemia and methylenetetrafolate reductase (C677T) gene polymorphism with cognitive impairment: A population based study from North India.
Topics: Adult; Aged; Cognitive Dysfunction; Comorbidity; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Vitamin B 12 | 2018 |
Role of hyperhomocysteinemia in proliferative diabetic retinopathy: A case-control study.
Topics: Adult; Aged; Blood Glucose; Case-Control Studies; Diabetic Retinopathy; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2018 |
A case report of branch retinal artery occlusion in a teenager due to hyperhomocysteinaemia; the interplay of genetic and nutritional defects.
Topics: Adolescent; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Methylenetetrahydrofolate Reductase (NADPH2); Retinal Artery Occlusion; Vision Disorders; Visual Acuity; Visual Field Tests; Visual Fields; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Folate/Vitamin B Alleviates Hyperhomocysteinemia-Induced Alzheimer-Like Pathologies in Rat Retina.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Dietary Supplements; Disease Models, Animal; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Rats, Sprague-Dawley; Retina; Retinal Vessels; tau Proteins; Vitamin B 12 | 2019 |
The serum homocysteine level in patients with acute ischemic stroke (AIS) after thrombolysis and its relationship with clinical outcomes.
Topics: Administration, Intravenous; Aged; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Risk Factors; ROC Curve; Severity of Illness Index; Stroke; Thrombolytic Therapy | 2018 |
Hyperhomocysteinemia Causes Chorioretinal Angiogenesis with Placental Growth Factor Upregulation.
Topics: Animals; Capillaries; Choroid; Disease Models, Animal; Fluorescein Angiography; Fundus Oculi; Homocysteine; Hyperhomocysteinemia; Male; Placenta Growth Factor; Rats, Sprague-Dawley; Retina; Tomography, Optical Coherence; Up-Regulation | 2018 |
The Association Between Tea Consumption and Hyperhomocysteine in Chinese Hypertensive Patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Blood Pressure; China; Cross-Sectional Studies; Female; Habits; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Prognosis; Protective Factors; Recommended Dietary Allowances; Retrospective Studies; Risk Assessment; Risk Factors; Tea; Up-Regulation | 2019 |
Homocysteine and age-associated disorders.
Topics: Aged; Aging; Bone Diseases; Chronic Disease; Hearing Loss; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Quality of Life; Renal Insufficiency; Risk Factors | 2019 |
Impaired Homocysteine Metabolism Associated with High Plasma Interleukin-17A Levels, a Pro-Atherogenic Marker, in an Endogamous Population of North India.
Topics: Adult; Biomarkers; Female; Forkhead Transcription Factors; Homocysteine; Humans; Hyperhomocysteinemia; India; Interleukin-10; Interleukin-17; Leukocytes, Mononuclear; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Population Surveillance; Prevalence; Vitamin B 12 | 2018 |
Methanolic extract of
Topics: Alzheimer Disease; Animals; Homocysteine; Hyperhomocysteinemia; Male; Memory Disorders; Methanol; Neurons; Oxidative Stress; Phosphorus Compounds; Phosphotransferases; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Tamaricaceae; tau Proteins | 2018 |
Gender differences in homocysteine concentrations, a population-based cross-sectional study.
Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Biomarkers; Coronary Artery Disease; Cross-Sectional Studies; Female; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Israel; Male; Middle Aged; Prevalence; Prognosis; Risk Factors; Sex Factors; Vitamin B 12 Deficiency; Young Adult | 2019 |
Hydrogen Sulfide Ameliorates Developmental Impairments of Rat Offspring with Prenatal Hyperhomocysteinemia.
Topics: Animals; Antioxidants; Brain; Female; Glutathione Peroxidase; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Lipid Peroxidation; Locomotion; Malondialdehyde; Pregnancy; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Sulfides; Superoxide Dismutase | 2018 |
The immunomodulatory mechanism of brain injury induced by hyperhomocysteinemia in spontaneously hypertensive rats.
Topics: Animals; Blood-Brain Barrier; Brain Injuries; Forkhead Transcription Factors; Homocysteine; Humans; Hyperhomocysteinemia; Immunomodulation; Inflammation; Interleukin-10; Interleukin-17; Interleukin-6; Methionine; Nuclear Receptor Subfamily 1, Group F, Member 3; Rats; Rats, Inbred SHR; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Transforming Growth Factor beta | 2019 |
Supplementation with dairy matrices impacts on homocysteine levels and gut microbiota composition of hyperhomocysteinemic mice.
Topics: Animals; Diet; Disease Models, Animal; Fermented Foods; Folic Acid; Gastrointestinal Microbiome; Homocysteine; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Milk | 2020 |
Betaine-homocysteine
Topics: Animals; Apoptosis; Betaine-Homocysteine S-Methyltransferase; Chromatography, High Pressure Liquid; Cochlea; Female; Gene Expression Profiling; Genotype; Hearing; Hearing Loss, Noise-Induced; Homocysteine; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prognosis; Time Factors | 2019 |
NRP1 regulates HMGB1 in vascular endothelial cells under high homocysteine condition.
Topics: Adult; Animals; Biomarkers; Case-Control Studies; Coculture Techniques; Disease Models, Animal; Female; HMGB1 Protein; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Inflammation; Inflammation Mediators; Male; Middle Aged; Neuropilin-1; p38 Mitogen-Activated Protein Kinases; Rats, Sprague-Dawley; Signal Transduction; THP-1 Cells; Up-Regulation | 2019 |
Metabolomic study of altered energy metabolism during global forebrain ischemia and ischemic precoditioning in blood plasma in homocysteine treated rats.
Topics: Animals; Biomarkers; Brain Ischemia; Disease Models, Animal; Energy Metabolism; Homocysteine; Hyperhomocysteinemia; Ischemic Preconditioning; Magnetic Resonance Spectroscopy; Male; Metabolomics; Prosencephalon; Rats; Rats, Wistar | 2018 |
Relationship between Homocysteine, Folate, Vitamin B
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Hand Strength; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Lower Extremity; Male; Muscle Strength; Nutritional Status; Physical Functional Performance; Regression Analysis; Sex Factors; Vitamin B 12 | 2019 |
The relationship between plasma homocysteine levels and MTHFR gene variation, age, and sex in Northeast China.
Topics: Adult; Age Factors; Aged; Asian People; Cardiovascular Diseases; China; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Sex Factors; Stroke | 2019 |
Negative Correlation Between Serum Levels of Homocysteine and Apolipoprotein M.
Topics: Apolipoproteins M; Case-Control Studies; Female; Hep G2 Cells; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Male; Middle Aged; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger | 2019 |
Hyperhomocysteinemia leads to exacerbation of ischemic brain damage: Role of GluN2A NMDA receptors.
Topics: Animals; Behavior, Animal; Brain; Brain Ischemia; Disease Models, Animal; Disease Progression; Homocysteine; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mice; Mice, Knockout; Motor Activity; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Rotarod Performance Test; Severity of Illness Index; Signal Transduction | 2019 |
Co-relation of Cerebral Venous Sinus Thrombosis with Vitamin B12 and Homocysteine Levels in a Tertiary Care Centre.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Sinus Thrombosis, Intracranial; Tertiary Care Centers; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Associations among serum folate, waist-to-hip ratio, lipid profile, and eating habits with homocysteine in an elderly Thai population.
Topics: Aged; Cross-Sectional Studies; Feeding Behavior; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Thailand; Vitamin B 12; Waist-Hip Ratio | 2019 |
Study of the Inflammatory Mechanisms in Hyperhomocysteinemia on Large-Artery Atherosclerosis Based on Hypersensitive C-Reactive Protein-A Study from Southern China.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Carotid Intima-Media Thickness; Carotid Stenosis; Case-Control Studies; China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Inflammation Mediators; Intracranial Arteriosclerosis; Male; Middle Aged; Plaque, Atherosclerotic; Prognosis; Risk Factors; Rupture, Spontaneous; Severity of Illness Index | 2019 |
Association between Homocysteine and Arterial Stiffness in Women with a History of Preeclampsia.
Topics: Adult; Biomarkers; Blood Pressure; Case-Control Studies; China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Peripheral Arterial Disease; Pre-Eclampsia; Pregnancy; Prognosis; Risk Assessment; Risk Factors; Time Factors; Vascular Stiffness | 2019 |
Investigation of the association between C677T polymorphism of the MTHFR gene and plasma homocysteine level in recurrent fetal miscarriage.
Topics: Abortion, Habitual; Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy | 2019 |
Association Between Cognitive Impairment and Vitamin B12, Folate, and Homocysteine Status in Elderly Adults: A Retrospective Study.
Topics: Aged; Aged, 80 and over; Biomarkers; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Hyperhomocysteinemia in female migraineurs of childbearing ages.
Topics: Adolescent; Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Migraine Disorders; Migraine with Aura; Migraine without Aura; Reproductive Health; Risk Factors; Stroke; Young Adult | 2019 |
Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in atrophic glossitis patients with or without microcytosis.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Erythropoiesis; Female; Folic Acid; Folic Acid Deficiency; Glossitis; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Iron Deficiencies; Male; Middle Aged; Parietal Cells, Gastric; Tongue; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2019 |
Evaluation of hyperhomocysteinemia prevalence and its influence on the selected cognitive functions in patients with schizophrenia.
Topics: Adult; Cognition; Cognitive Dysfunction; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neuropsychological Tests; Prevalence; Schizophrenia; Schizophrenic Psychology | 2019 |
Hyperhomocysteinemia is an independent risk factor for intracranial aneurysms: a case-control study in a Chinese Han population.
Topics: Adult; Age Factors; Aged; Asian People; Case-Control Studies; China; Confidence Intervals; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Aneurysm; Logistic Models; Male; Middle Aged; Regression Analysis; Retrospective Studies; Risk Factors | 2020 |
Does serum gastric parietal cell antibody titer have influence on anemia and vitamin B12 deficiency in atrophic glossitis patients?
Topics: Adult; Aged; Aged, 80 and over; Anemia, Macrocytic; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Tongue; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Evaluation of Plasma Homocysteine Levels in Patients of PCOS.
Topics: Case-Control Studies; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Insulin Resistance; Male; Polycystic Ovary Syndrome; Pregnancy | 2018 |
Hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with macrocytosis.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Anemia, Macrocytic; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hematinics; Hematologic Diseases; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Tongue; Vitamin B 12; Young Adult | 2019 |
Hyperhomocysteinemia is key for increased susceptibility to PND in aged mice.
Topics: Animals; Cognition; Dietary Supplements; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Postoperative Cognitive Complications; Postoperative Period; Preoperative Period; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2019 |
Hyperhomocysteinemia in a Gammopathy Patient: Malnutrition or Interference?
Topics: Aged, 80 and over; False Positive Reactions; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Waldenstrom Macroglobulinemia | 2019 |
A potential role for T-type calcium channels in homocysteinemia-induced peripheral neuropathy.
Topics: Animals; Calcium; Calcium Channels, T-Type; Cell Membrane; Disease Models, Animal; Ganglia, Spinal; Homocysteine; Hyperalgesia; Hyperhomocysteinemia; Nociception; Peripheral Nervous System Diseases; Rats; Rats, Wistar | 2019 |
A novel approach in the management of hyperhomocysteinemia.
Topics: Alcohol Oxidoreductases; Animals; Choline; Cytidine Diphosphate Choline; Dietary Supplements; Endothelial Cells; Folic Acid; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Kidney; Life Style; Liver; Methionine; Models, Theoretical; Vitamin B 12; Vitamin B 6 | 2019 |
[Influence of elevated homocystein level and selected lipid parameters in kidney transplant patients on the progression of atherosclerotic changes assessed by intima-media thickness index (CCA-IMT)].
Topics: Adolescent; Adult; Apolipoproteins B; Atherosclerosis; Biomarkers; Carotid Artery, Common; Carotid Intima-Media Thickness; Disease Progression; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Lipoprotein(a); Male; Middle Aged; Young Adult | 2012 |
Quercetin reduces serum homocysteine level in rats fed a methionine-enriched diet.
Topics: Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; Glutathione; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Liver; Male; Malondialdehyde; Methionine; Organ Size; Oxidative Stress; Protein Carbonylation; Quercetin; Random Allocation; Rats; Rats, Wistar; Weight Gain | 2013 |
Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia.
Topics: Case-Control Studies; CpG Islands; DNA Methylation; Epigenesis, Genetic; Female; Folate Receptor 1; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Leukocytes; Neural Tube Defects; Placenta; Polymorphism, Single Nucleotide; Pregnancy; Proton-Coupled Folate Transporter; Replication Protein C; RNA, Messenger; Transcription, Genetic | 2013 |
Hyperhomocysteinemia promotes insulin resistance by inducing endoplasmic reticulum stress in adipose tissue.
Topics: Adipocytes; Adipose Tissue; Animals; Cytokines; Diabetes Mellitus, Type 2; Endoplasmic Reticulum; Glucose; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Inflammation; Insulin; Insulin Resistance; Macrophages; Macrophages, Peritoneal; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2013 |
Homocysteine, cysteine, and risk of incident colorectal cancer in the Women's Health Initiative observational cohort.
Topics: Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Cohort Studies; Colonic Neoplasms; Cysteine; Ethnicity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Observation; Odds Ratio; Postmenopause; Rectal Neoplasms; Risk Factors | 2013 |
Hepatocyte-specific Dyrk1a gene transfer rescues plasma apolipoprotein A-I levels and aortic Akt/GSK3 pathways in hyperhomocysteinemic mice.
Topics: Animals; Aorta; Apolipoprotein A-I; Cystathionine beta-Synthase; Dyrk Kinases; Genetic Therapy; Hepatocytes; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Mutant Strains; Organ Specificity; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Transduction, Genetic | 2013 |
Hyperhomocysteinemia is an independent risk factor in young patients with coronary artery disease in southern China.
Topics: Biomarkers; China; Comorbidity; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Reproducibility of Results; Risk Factors; Sensitivity and Specificity | 2013 |
Brachial artery aneurysm accompanying a homozygous methylenetetrahydrofolate reductase mutation.
Topics: Adult; Aneurysm; Biomarkers; Brachial Artery; DNA Mutational Analysis; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Phenotype; Saphenous Vein; Treatment Outcome; Vascular Grafting | 2013 |
Assessment of mitochondrial electron transport chain function in a primary astrocyte cell model of hyperhomocystinaemia.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Dose-Response Relationship, Drug; Electron Transport Chain Complex Proteins; Glutathione; Homocysteine; Hyperhomocysteinemia; Mitochondria; Models, Biological; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Time Factors | 2013 |
Mild hyperhomocysteinemia reduces the activity and immunocontent, but does not alter the gene expression, of catalytic α subunits of cerebral Na+,K+-ATPase.
Topics: Animals; Blotting, Western; Catalytic Domain; Cerebral Cortex; Hippocampus; Homocysteine; Hyperhomocysteinemia; Protein Subunits; Rats; Rats, Wistar; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Transcription, Genetic | 2013 |
Hyperhomocysteinemia associates with small vessel disease more closely than large vessel disease.
Topics: Aged; Brain Ischemia; Cerebral Arteries; Female; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Middle Aged; Radiography; Risk Factors; Stroke | 2013 |
Vitamin B12 deficiency and hyperhomocysteinemia as correlates of cardiovascular risk factors in Indian subjects with coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Coronary Artery Disease; Dyslipidemias; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Homocysteine alters the osteoprotegerin/RANKL system in the osteoblast to promote bone loss: pivotal role of the redox regulator forkhead O1.
Topics: Acetylcysteine; Animals; Cells, Cultured; Female; Forkhead Transcription Factors; Homocysteine; Hyperhomocysteinemia; Nerve Tissue Proteins; Osteoblasts; Osteoporosis; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Protein Phosphatase 2; RANK Ligand; Rats; Rats, Sprague-Dawley | 2013 |
Inhibition of cystathionine β-synthase is associated with glucocorticoids over-secretion in psychological stress-induced hyperhomocystinemia rat liver.
Topics: Animals; Cell Nucleus; Cells, Cultured; Corticosterone; Cystathionine beta-Synthase; Glucocorticoids; Hepatocytes; Homocysteine; Hyperhomocysteinemia; Male; Models, Animal; Promoter Regions, Genetic; Protein Binding; Rats; Rats, Wistar; Receptors, Glucocorticoid; RNA, Messenger; Sp1 Transcription Factor; Sp3 Transcription Factor; Stress, Psychological; Up-Regulation | 2013 |
Small renal size in newborns with spina bifida: possible causes.
Topics: Biomarkers; Case-Control Studies; Creatinine; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Insulin-Like Growth Factor I; Kidney; Organ Size; Spinal Dysraphism; Ultrasonography | 2014 |
Testing for hyperhomocysteinemia in subjects with a history of thromboembolic events using HPLC technique.
Topics: Chromatography, High Pressure Liquid; Homocysteine; Humans; Hyperhomocysteinemia; Thromboembolism; Thrombophilia | 2013 |
Heart dysfunction induced by choline-deficiency in adult rats: the protective role of L-carnitine.
Topics: Animals; Cardiotonic Agents; Carnitine; Choline Deficiency; Dietary Supplements; Edema, Cardiac; Fibrosis; Heart Valves; Heart Ventricles; Homocysteine; Hyperhomocysteinemia; Lymphocytes; Male; Myocardial Contraction; Natriuretic Peptide, Brain; Random Allocation; Rats; Rats, Wistar; Ventricular Dysfunction, Left | 2013 |
Hyperhomocysteinemia is detrimental to pregnancy in mice and is associated with preterm birth.
Topics: Animals; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystathionine beta-Synthase; Dinoprostone; Female; Homocysteine; Humans; Hyperhomocysteinemia; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Mice; Mice, Inbred C57BL; Muscle Contraction; Myometrium; Placenta; Pregnancy; Pregnancy Complications; Premature Birth; Receptors, Nicotinic; Receptors, Oxytocin; Trophoblasts; Up-Regulation; Uterus | 2013 |
MTHFR C677T polymorphism, folate, vitamin B12 and homocysteine in recurrent pregnancy losses: a case control study among North Indian women.
Topics: Abortion, Habitual; Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; India; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Hyperhomocysteinia is a risk factor for retinal venous occlusion: a case control study.
Topics: Adolescent; Adult; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; India; Male; Middle Aged; Ophthalmoscopy; Retinal Vein Occlusion; Retrospective Studies; Risk Assessment; Risk Factors; Young Adult | 2014 |
Homocysteine, antioxidant micronutrients and late onset dementia.
Topics: Aged; Aged, 80 and over; Antioxidants; Body Mass Index; Cognition; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Micronutrients; Nutrition Assessment; Proportional Hazards Models; Risk Factors; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12 | 2014 |
Methylenetetrahydrofolate reductase (C677T and A1298C) polymorphisms, hyperhomocysteinemia, and ischemic stroke in Tunisian patients.
Topics: Adult; Aged; Biomarkers; Brain Ischemia; Case-Control Studies; Chi-Square Distribution; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Phenotype; Polymorphism, Genetic; Risk Factors; Stroke; Tunisia; Up-Regulation | 2013 |
Plasma total homocysteine is associated with abdominal aortic aneurysm and aortic diameter in older men.
Topics: Age Factors; Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Biomarkers; Comorbidity; Cross-Sectional Studies; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoassay; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Odds Ratio; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Assessment; Risk Factors; Sex Factors; Ultrasonography; Up-Regulation; Western Australia | 2013 |
[Effect of homocysteine on gluconeogenesis in mice].
Topics: Animals; Gluconeogenesis; Glucose-6-Phosphatase; Homocysteine; Hyperhomocysteinemia; Insulin Resistance; Liver; Male; Mice; Mice, Inbred Strains; Phosphoenolpyruvate Carboxykinase (ATP) | 2013 |
Selective homocysteine lowering gene transfer improves infarct healing, attenuates remodelling, and enhances diastolic function after myocardial infarction in mice.
Topics: Adenoviridae; Animals; Cystathionine beta-Synthase; Diastole; Diet, High-Fat; Female; Genetic Vectors; Heart; Heart Failure; Homocysteine; Homocystinuria; Hypercholesterolemia; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Receptors, LDL; Transgenes; Ventricular Remodeling | 2013 |
Effects of hyperhomocysteinemia and betaine-homocysteine S-methyltransferase inhibition on hepatocyte metabolites and the proteome.
Topics: Apolipoprotein A-I; Apoptosis; Betaine-Homocysteine S-Methyltransferase; Blotting, Western; Cell Proliferation; Cells, Cultured; Colorectal Neoplasms; Electrophoresis, Gel, Two-Dimensional; Fibrinogen; Hepatocytes; Homocysteine; Humans; Hyperhomocysteinemia; Liver Neoplasms; Male; Metabolomics; Middle Aged; Protein Multimerization; Proteome; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Association of serum homocysteine with major depressive disorder: results from a large population-based study.
Topics: Adult; Aged; Depressive Disorder, Major; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Factors; Socioeconomic Factors; Switzerland | 2013 |
[Effect of homocysteine on left ventricular structural and functional parameters in patients on programmed hemodialysis].
Topics: Adult; Female; Heart Ventricles; Homocysteine; Humans; Hyperhomocysteinemia; Hypertrophy, Left Ventricular; Male; Middle Aged; Renal Dialysis; Structure-Activity Relationship; Ultrasonography; Ventricular Remodeling | 2013 |
Plasma homocysteine and folate levels and dietary folate intake in adolescents and young adults who underwent kidney transplantation during childhood.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Age Factors; Biomarkers; Cardiovascular Diseases; Child; Child Nutritional Physiological Phenomena; Cross-Sectional Studies; Diet; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Kidney; Kidney Transplantation; Linear Models; Male; Nutrition Assessment; Nutritional Status; Prevalence; Risk Factors; Time Factors; Treatment Outcome; Vitamin B Deficiency; Young Adult | 2014 |
Homocysteine levels and cognitive function scores measured with MMSE and BCAT of middle-aged and elderly subjects in Tianjin City.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; China; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intelligence Tests; Linear Models; Male; Middle Aged; Neuropsychological Tests; Prevalence; Sex Factors; Surveys and Questionnaires | 2013 |
Exercise prevents hyperhomocysteinemia in a dietary folate-restricted mouse model.
Topics: Absorption; Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Disease Models, Animal; Female; Folic Acid; Homocysteine; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Physical Conditioning, Animal | 2013 |
Methionine-induced hyperhomocysteinemia impairs the antioxidant ability of high-density lipoproteins without reducing in vivo macrophage-specific reverse cholesterol transport.
Topics: Animals; Antioxidants; Apolipoprotein A-I; Aryldialkylphosphatase; Atherosclerosis; Biological Transport; Cell Line; Cholesterol, HDL; Disease Models, Animal; Female; Homocysteine; Hyperhomocysteinemia; Lipid Metabolism; Liver; Macrophages; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2013 |
[Effects of plasma Hcy on the contents of CO and HO-2 in the corpus cavernosum of ED rats with hyperhomocysteinemia].
Topics: Animals; Carbon Monoxide; Erectile Dysfunction; Heme Oxygenase (Decyclizing); Homocysteine; Hyperhomocysteinemia; Male; Penis; Rats; Rats, Wistar | 2013 |
Plasma total homocysteine is associated with DNA methylation in patients with schizophrenia.
Topics: CpG Islands; DNA Methylation; Homocysteine; Humans; Hyperhomocysteinemia; Leukocytes; Male; Middle Aged; Schizophrenia | 2013 |
Echocardiographic assessment of hypertensive patients with or without hyperhomocysteinemia.
Topics: Adult; Aged; Diastole; Echocardiography; Female; Heart Ventricles; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Ventricular Dysfunction, Left; Ventricular Function, Left | 2014 |
Helicobacter pylori infection and homocysteine levels in patients with cardiac syndrome X.
Topics: Female; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Hyperhomocysteinemia; Male; Microvascular Angina | 2013 |
Hypertension in pregnancy is associated with elevated homocysteine levels later in life.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Pregnancy-Induced; Linear Models; Logistic Models; Middle Aged; Pregnancy; Time Factors | 2013 |
Effects of allicin on hyperhomocysteinemia-induced experimental vascular endothelial dysfunction.
Topics: Animals; Aorta; Disulfides; Endothelins; Endothelium, Vascular; Fibroblast Growth Factor 2; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar; Sulfinic Acids; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2013 |
Nutrition throughout life: folate.
Topics: Biological Availability; Cardiovascular Diseases; Drug Stability; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Neural Tube Defects; Nutrition Policy; Nutritional Physiological Phenomena; Nutritional Requirements; Nutritional Status; Pregnancy | 2012 |
Genetic variants reducing MTR gene expression increase the risk of congenital heart disease in Han Chinese populations.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Asian People; Case-Control Studies; DNA Methylation; Ferredoxin-NADP Reductase; Gene Expression; Genetic Predisposition to Disease; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; MicroRNAs; Risk Factors; Transcription, Genetic | 2014 |
Effect of multivitamins on plasma homocysteine in patients with the 5,10 methylenetetrahydrofolate reductase C677T homozygous state.
Topics: Adult; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Vitamin B 12; Vitamins | 2013 |
Hyperhomocysteinemia as a consequence of life style among patients suffering from thromboangiitis obliterans.
Topics: Biomarkers; Case-Control Studies; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Malnutrition; Odds Ratio; Risk Factors; Smoking; Socioeconomic Factors; Thromboangiitis Obliterans; Up-Regulation | 2013 |
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and variations of homocysteine concentrations in patients with Behcet's disease.
Topics: Adult; Behcet Syndrome; Case-Control Studies; Cobamides; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Young Adult | 2013 |
[The clinical studies of hyperhomocysteinemia and Alzheimer's disease].
Topics: Alzheimer Disease; Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 2013 |
Neuropathy and levodopa in Parkinson's disease: evidence from a multicenter study.
Topics: Aged; Antiparkinson Agents; Female; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Logistic Models; Male; Middle Aged; Neural Conduction; Parkinson Disease; Peripheral Nervous System Diseases; Prevalence; Risk; Vitamin B 12 | 2013 |
Changes in body composition predict homocysteine changes and hyperhomocysteinemia in Korea.
Topics: Adipose Tissue; Body Composition; Body Mass Index; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Republic of Korea | 2013 |
Folic acid attenuates hyperhomocysteinemia-induced glomerular damage in rats.
Topics: Albuminuria; Animals; Cell Proliferation; Collagen; Creatinine; Folic Acid; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Kidney; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Podocytes; Random Allocation; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Up-Regulation | 2013 |
Plasma homocysteine concentrations in the acute phase after central retinal vein occlusion in a Chinese population.
Topics: Acute Disease; Aged; Asian People; Cardiovascular Diseases; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2013 |
The role of hyperhomocysteinemia in neurological features associated with coeliac disease.
Topics: Blood-Brain Barrier; Celiac Disease; Child; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Neurons; Vitamin B Deficiency | 2013 |
Hyperhomocysteinemia and vascular access thrombosis in hemodialysis patients: a retrospective study.
Topics: Aged; Aspirin; Biomarkers; Chi-Square Distribution; Diabetes Complications; Female; Fibrinolytic Agents; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney Failure, Chronic; Logistic Models; Male; Middle Aged; Renal Dialysis; Retrospective Studies; Risk Factors; Thrombosis; Up-Regulation | 2013 |
Impact of hyperhomocysteinemia on breast cancer initiation and progression: epigenetic perspective.
Topics: BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Homocysteine; Humans; Hyperhomocysteinemia; MCF-7 Cells; Membrane Proteins; Microtubule-Associated Proteins; Proto-Oncogene Proteins; Transcriptome; Tumor Suppressor Proteins; Vitamin B 12 | 2014 |
Gene-environment and gene-gene interactions of specific MTHFR, MTR and CBS gene variants in relation to homocysteine in black South Africans.
Topics: Adult; Cystathionine beta-Synthase; Epistasis, Genetic; Female; Gene-Environment Interaction; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Phosphotransferases (Alcohol Group Acceptor); Polymorphism, Single Nucleotide; South Africa | 2013 |
Relationship between metformin use, vitamin B12 deficiency, hyperhomocysteinemia and vascular complications in patients with type 2 diabetes.
Topics: Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Japan; Male; Metformin; Middle Aged; Prevalence; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Mechanism of hyperhomocysteinemia-induced vascular endothelium dysfunction - possible dysregulation of phosphatidylinositol-3-kinase and its downstream phosphoinositide dependent kinase and protein kinase B.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Acetylcholine; Animals; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Male; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; RNA, Messenger; Vasodilation | 2013 |
Homocysteine-related hTERT DNA demethylation contributes to shortened leukocyte telomere length in atherosclerosis.
Topics: Animals; Atherosclerosis; Epigenesis, Genetic; Homocysteine; Humans; Hyperhomocysteinemia; Leukocytes; Mice; Telomerase; Telomere; Telomere Shortening | 2013 |
Clinical significance of determining plasma homocysteine: case-control study on arterial and venous thrombotic patients.
Topics: Adolescent; Adult; Case-Control Studies; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Risk Factors; Venous Thrombosis; Young Adult | 2013 |
Hyperhomocysteinemia in bipolar depression: clinical and biochemical correlates.
Topics: Adult; Aged; Biomarkers; Bipolar Disorder; E-Selectin; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Middle Aged; Vitamin B 12; Young Adult | 2013 |
Dietary protein and plasma total homocysteine, cysteine concentrations in coronary angiographic subjects.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Coronary Angiography; Cross-Sectional Studies; Cysteine; Dietary Proteins; Female; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Multivariate Analysis; Surveys and Questionnaires | 2013 |
Isolated abducens nerve palsy with hyperhomocysteinemia: association and outcomes.
Topics: Abducens Nerve Diseases; Adolescent; Adult; Child; Diagnosis, Differential; Diplopia; Eye Movements; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Retrospective Studies; Risk Factors; Young Adult | 2013 |
Association of homocysteinaemia with hyperglycaemia, dyslipidaemia, hypertension and obesity.
Topics: Adult; Biomarkers; Blood Glucose; Blood Pressure; Cross-Sectional Studies; Dyslipidemias; Female; Homocysteine; Humans; Hyperglycemia; Hyperhomocysteinemia; Hypertension; Lipids; Male; Metabolic Syndrome; Middle Aged; Obesity; Prospective Studies; Risk Factors; South Africa | 2013 |
Plasma homocysteine, folic acid, and vitamin B₁₂ levels in patients with pseudoexfoliation syndrome, pseudoexfoliation glaucoma, and normotensive glaucoma.
Topics: Aged; Exfoliation Syndrome; Female; Folic Acid; Glaucoma; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12 | 2013 |
Hyperhomocysteinemia and hyperlipoproteinemia (a) in obese South Indian men: an indication for increased cardiovascular risk.
Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Biomarkers; Body Mass Index; Cardiovascular Diseases; Case-Control Studies; Comorbidity; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipoproteinemias; India; Lipoprotein(a); Male; Obesity; Risk Factors; Up-Regulation; Waist Circumference; Waist-Hip Ratio; Young Adult | 2014 |
The control of hyperhomocysteinemia through thiol exchange mechanisms by mesna.
Topics: Adult; Antioxidants; Drug Evaluation, Preclinical; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mesna; Methionine; Middle Aged; Oxidation-Reduction | 2014 |
Maternal methyl donors supplementation during lactation prevents the hyperhomocysteinemia induced by a high-fat-sucrose intake by dams.
Topics: Animals; Body Weight; Diet, High-Fat; Dietary Sucrose; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Female; Homocysteine; Hyperhomocysteinemia; Lactation; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylmethionine | 2013 |
Association of polymorphisms on chromosome 9p21.3 region with increased susceptibility of abdominal aortic aneurysm in a Chinese Han population.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Chromosomes, Human, Pair 9; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Factors | 2014 |
Unique features of non-obstructive emphysema and pure airway obstruction.
Topics: Adult; Aged; Airway Obstruction; Biomarkers; Body Mass Index; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoalbuminemia; Leukocyte Count; Logistic Models; Lung; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Osteoporosis; Pulmonary Emphysema; Republic of Korea; Respiratory Function Tests; Retrospective Studies; Risk Factors; Serum Albumin; Serum Albumin, Human; Tomography, X-Ray Computed | 2014 |
Homocysteinylation score of high-molecular weight plasma proteins.
Topics: Adult; Aged; Aged, 80 and over; Blood Proteins; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Molecular Weight; Protein Binding | 2014 |
Smokeless tobacco use: a risk factor for hyperhomocysteinemia in a Pakistani population.
Topics: Adolescent; Adult; Cities; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Income; Male; Middle Aged; Pakistan; Pyridoxal Phosphate; Risk Factors; Tobacco, Smokeless; Vitamin B 12; Young Adult | 2013 |
Folic acid mitigates angiotensin-II-induced blood pressure and renal remodeling.
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Collagen; Drinking; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Hypertension; Kidney; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; RNA, Messenger; Tissue Inhibitor of Metalloproteinases | 2013 |
The relationship between plasma homocysteine level and HLA-B51 in patients with Behcet's disease: a case-control study.
Topics: Adult; Behcet Syndrome; Biomarkers; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; HLA-B51 Antigen; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Male; Prevalence; Risk Factors; Young Adult | 2014 |
Serum homocysteine level is positively associated with chronic kidney disease in a Taiwan Chinese population.
Topics: Adult; Aged; Asian People; Biomarkers; Chi-Square Distribution; China; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Life Style; Linear Models; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Predictive Value of Tests; Renal Insufficiency, Chronic; Risk Factors; Taiwan; Tertiary Care Centers; Time Factors; Up-Regulation | 2014 |
Higher homocysteine levels in young Indian adults: impact of vitamin B12 & folate deficiencies.
Topics: Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2) | 2013 |
Dietary intake, plasma homocysteine, and repetitive element DNA methylation in the Multi-Ethnic Study of Atherosclerosis (MESA).
Topics: Aged; Aged, 80 and over; Alu Elements; Atherosclerosis; Biomarkers; Body Height; Body Mass Index; Cross-Sectional Studies; Diet; DNA Methylation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Long Interspersed Nucleotide Elements; Los Angeles; Male; Micronutrients; Middle Aged; New York City; Obesity, Morbid; Risk Factors | 2014 |
Homocysteine and progression of generalized small-vessel disease: the SMART-MR Study.
Topics: Age Factors; Aged; Atrophy; Brain; Cerebrovascular Disorders; Disease Progression; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Middle Aged; Nerve Fibers, Myelinated; Prospective Studies; Risk Factors; Sex Factors | 2014 |
C677T methylenetetrahydrofolate reductase and plasma homocysteine levels among Thai vegans and omnivores.
Topics: Adult; Diet, Vegetarian; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Vitamin B 12 | 2013 |
Hyperhomocysteinemia and bleomycin hydrolase modulate the expression of mouse brain proteins involved in neurodegeneration.
Topics: Analysis of Variance; Animals; Brain; Cysteine Endopeptidases; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Genotype; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
An MTHFR variant, plasma homocysteine levels and late-onset coronary artery disease in subjects from southern Iran.
Topics: Age of Onset; Aged; Biomarkers; Chi-Square Distribution; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Phenotype; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors | 2013 |
Comment on: “methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and variations of homocysteine concentrations in patients with Behcet's disease”.
Topics: Behcet Syndrome; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide | 2014 |
Authors' response.
Topics: Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2) | 2013 |
[Pulmonary embolism in young adults. Think of homocysteine].
Topics: Adult; Anticoagulants; Biomarkers; Drug Therapy, Combination; Female; Heparin; Homocysteine; Humans; Hyperhomocysteinemia; Pulmonary Embolism; Risk Factors; Treatment Outcome; Vitamin B 6; Vitamin B Complex; Young Adult | 2014 |
Homocysteine and risk of periprocedural myocardial infarction in patients undergoing coronary stenting.
Topics: Aged; Aged, 80 and over; Biomarkers; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Risk Factors; Stents | 2015 |
Hyperhomocysteinemia-induced myocardial infarction in a young male using anabolic steroids.
Topics: Adult; Anabolic Agents; Electrocardiography; Emergency Service, Hospital; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction | 2014 |
Hyperhomocysteinemia is a risk factor for Alzheimer's disease in an Algerian population.
Topics: Aged; Aged, 80 and over; Algeria; Alzheimer Disease; Case-Control Studies; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Risk Factors; Thyrotropin; Uric Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
Coronary flow velocity reserve is impaired in hypertensive patients with hyperhomocysteinemia.
Topics: Blood Flow Velocity; Coronary Vessels; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin Resistance; Male; Middle Aged; Regression Analysis | 2014 |
Relationship between homocysteine levels and hypertension in systemic lupus erythematosus.
Topics: Adult; Biomarkers; Blood Pressure; Body Mass Index; Case-Control Studies; Chi-Square Distribution; Cross-Sectional Studies; Female; Glucocorticoids; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Linear Models; Logistic Models; Lupus Erythematosus, Systemic; Middle Aged; Multivariate Analysis; Odds Ratio; Prednisone; Prevalence; Pulse Wave Analysis; Risk Factors; Spain; Vascular Stiffness | 2014 |
Dietary carotenoids are associated with cardiovascular disease risk biomarkers mediated by serum carotenoid concentrations.
Topics: Adult; beta Carotene; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Carotenoids; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Diet; Female; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Lutein; Lycopene; Male; Nutrition Surveys; Risk Factors; United States; Xanthophylls; Zeaxanthins | 2014 |
Hydrogen sulfide inhibits homocysteine-induced endoplasmic reticulum stress and neuronal apoptosis in rat hippocampus via upregulation of the BDNF-TrkB pathway.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Line; Endoplasmic Reticulum Stress; Hippocampus; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptor, trkB; Signal Transduction; Up-Regulation | 2014 |
High plasma homocysteine increases risk of metabolic syndrome in 6 to 8 year old children in rural Nepal.
Topics: Biomarkers; Blood Pressure; Body Mass Index; Child; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Metabolic Syndrome; Nepal; Obesity, Abdominal; Prevalence; Risk Factors; Rural Population; Triglycerides; Waist Circumference | 2014 |
Alleviation of plasma homocysteine level by phytoestrogen α-zearalanol might be related to the reduction of cystathionine β-synthase nitration.
Topics: Animals; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Female; Homocysteine; Hyperhomocysteinemia; Liver; Nitrates; Oxidation-Reduction; Phytoestrogens; Rats; Rats, Wistar; Treatment Outcome; Tyrosine; Zeranol | 2014 |
What is new in obstetric antecedents of chronic disease? Best articles from the past year.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Diabetes, Gestational; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Pregnancy-Induced; Kidney Diseases; Obesity; Pregnancy; Premature Birth | 2014 |
Creatine prevents the imbalance of redox homeostasis caused by homocysteine in skeletal muscle of rats.
Topics: Animals; Catalase; Creatine; Female; Fluoresceins; Glutathione; Glutathione Peroxidase; Homeostasis; Homocysteine; Hyperhomocysteinemia; Male; Muscle, Skeletal; Nitrites; Oxidation-Reduction; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2014 |
Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism.
Topics: Acetylcholinesterase; Animals; Apoptosis; Betaine; Cerebellum; Choline; Choline O-Acetyltransferase; Disease Models, Animal; DNA Methylation; Ferredoxin-NADP Reductase; Gene Expression; Hippocampus; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Male; Memory, Short-Term; Methionine; Mice; Mice, Knockout; Synaptic Transmission | 2014 |
Multiple extra macular branch retinal vein occlusions in hyperhomocysteinemia.
Topics: Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retinal Vein Occlusion; Tomography, Optical Coherence | 2014 |
Elevated homocysteine and the risk of contrast-induced nephropathy: a cohort study.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Chi-Square Distribution; Contrast Media; Coronary Angiography; Coronary Artery Disease; Creatinine; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Logistic Models; Male; Odds Ratio; Percutaneous Coronary Intervention; Registries; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Up-Regulation | 2015 |
Influence of hyperhomocysteinemia on left ventricular diastolic function in Chinese patients with hypertension.
Topics: Biomarkers; Causality; China; Comorbidity; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Incidence; Male; Middle Aged; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity; Ventricular Dysfunction, Left | 2015 |
Immediate and long-term high levels of plasma homocysteine after extracorporeal shock wave lithotripsy in patients with renal stone disease.
Topics: Adult; Biomarkers; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Calculi; Lithotripsy; Male; Middle Aged; Oxidative Stress; Time Factors; Treatment Outcome; Up-Regulation | 2014 |
Hyperhomocysteinemia promotes vascular remodeling in vein graph in mice.
Topics: Animals; Blotting, Western; Carotid Arteries; Cell Proliferation; Cells, Cultured; Collagen; Cystathionine beta-Synthase; Elastin; Homocysteine; Hyperhomocysteinemia; Jugular Veins; Leukocyte Common Antigens; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Rats; Vascular Remodeling | 2014 |
Plasma homocysteine concentrations in acute and convalescent changes of central retinal vein occlusion in a Chinese population.
Topics: Aged; Biomarkers; China; DNA; Electroretinography; Female; Folic Acid; Follow-Up Studies; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Microscopy, Acoustic; Middle Aged; Ophthalmoscopy; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prognosis; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Time Factors; Tomography, Optical Coherence; Vitamin B 12 | 2014 |
Elevated serum homocysteine levels were not correlated with serum uric acid levels, but with decreased renal function in gouty patients.
Topics: Glomerular Filtration Rate; Gout; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency, Chronic; Severity of Illness Index; Uric Acid | 2014 |
Homocysteine induces blood vessel global hypomethylation mediated by LOX-1.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Vessels; DNA Methylation; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Mice; Scavenger Receptors, Class E | 2014 |
Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Randomized Controlled Trials as Topic; Vitamin B Complex | 2014 |
Hyperhomocysteinemia and assessment of its associated factors in renal transplant recipients: a single-center study in northern Iran.
Topics: Adult; Biomarkers; Blood Urea Nitrogen; Chi-Square Distribution; Creatinine; Cross-Sectional Studies; Cyclosporine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Iran; Kidney Failure, Chronic; Kidney Transplantation; Linear Models; Male; Middle Aged; Multivariate Analysis; Prevalence; Risk Factors; Time Factors; Vitamin B 12 | 2014 |
Domain specific changes in cognition at high altitude and its correlation with hyperhomocysteinemia.
Topics: Acclimatization; Adult; Altitude; Cognition; Cognitive Dysfunction; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Neuropsychological Tests; Vitamin B 12 | 2014 |
Vitamin status as a determinant of serum homocysteine concentration in type 2 diabetic retinopathy.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Prevalence; Regression Analysis; Risk Factors; Vitamin B 12; Vitamins | 2014 |
Hyperhomocysteinemia is one of the risk factors associated with cerebrovascular stiffness in hypertensive patients, especially elderly males.
Topics: Aged; Blood Pressure; Brain; C-Reactive Protein; Carotid Intima-Media Thickness; Cerebrovascular Disorders; Cholesterol; Cross-Sectional Studies; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipoproteins, HDL; Male; Middle Aged; Risk Factors; Uric Acid | 2014 |
Homocysteine induces the expression of C-reactive protein via NMDAr-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells.
Topics: Animals; Atherosclerosis; C-Reactive Protein; Cells, Cultured; Dizocilpine Maleate; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Interleukins; Male; MAP Kinase Signaling System; Methionine; Mitogen-Activated Protein Kinases; Myocytes, Smooth Muscle; NF-kappa B; Onium Compounds; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Signal Transduction; Superoxides; Thenoyltrifluoroacetone | 2014 |
Plasma total homocysteine: usual values and main determinants in adults living in the Great Tunis region.
Topics: Adult; Aged; Analysis of Variance; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Reference Values; Smoking; Tunisia; Vitamin B 12 Deficiency | 2014 |
Novel multipotent AChEI-CCB attenuates hyperhomocysteinemia-induced memory deficits and Neuropathologies in rats.
Topics: Animals; Brain Diseases; Calcium Channel Blockers; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Drug Therapy, Combination; Hippocampus; Homocysteine; Hyperhomocysteinemia; Indans; Male; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Nifedipine; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Silver Staining; Tacrine | 2014 |
Homocysteine, small-vessel disease, and atherosclerosis: an MRI study of 825 stroke patients.
Topics: Atherosclerosis; Brain Ischemia; Cerebral Arteries; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Retrospective Studies; Risk Factors; Stroke | 2014 |
Hyperhomocysteinemia induced by methionine dietary nutritional overload modulates acetylcholinesterase activity in the rat brain.
Topics: Acetylcholinesterase; Animals; Brain; Diet; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats, Wistar | 2014 |
Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells.
Topics: Animals; Brain; Endothelial Cells; Epigenesis, Genetic; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondria, Heart; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2015 |
High levels of homocysteine results in cerebral amyloid angiopathy in mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animal Feed; Animals; Brain; Cerebral Amyloid Angiopathy; Diet; Disease Models, Animal; Female; Homocysteine; Hyperhomocysteinemia; Male; Mice, Transgenic; Random Allocation | 2015 |
Plasma total homocysteine and carotid intima-media thickness in type 1 diabetes: a prospective study.
Topics: Adolescent; Adult; Age Factors; C-Reactive Protein; Carotid Intima-Media Thickness; Comorbidity; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Disease Progression; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipids; Male; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Smoking; Young Adult | 2014 |
Early markers of occult megaloblastosis for low-cost detection of hyperhomocysteinemia in patients with ischaemic stroke: preventive approach for primary health care.
Topics: Anemia, Megaloblastic; Biomarkers; Brain Ischemia; Early Diagnosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neutrophils; Primary Health Care; Stroke; Vitamin B 12 | 2014 |
Combined branch retinal artery and vein occlusion in hyperhomocysteinemia.
Topics: Blindness; Fluorescein Angiography; Glaucoma, Neovascular; Homocysteine; Humans; Hyperhomocysteinemia; Male; Retinal Artery Occlusion; Retinal Vein Occlusion | 2014 |
Homocysteine in patients with inflammatory bowel diseases.
Topics: Adult; Aged; Colitis, Ulcerative; Crohn Disease; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Middle Aged; Prospective Studies; Young Adult | 2014 |
Central and systemic responses to methionine-induced hyperhomocysteinemia in mice.
Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cysteine; Dose-Response Relationship, Drug; Drug Administration Schedule; Glutathione; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Mice; Motor Activity; Recognition, Psychology; Time Factors | 2014 |
Endothelial dysfunction and hyperhomocysteinemia in Parkinson's disease: flow-mediated dilation study.
Topics: Aged; Antiparkinson Agents; Brachial Artery; Catechols; Dilatation; Endothelium; Female; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Logistic Models; Male; Middle Aged; Nitriles; Parkinson Disease; Statistics, Nonparametric | 2014 |
Genetic polymorphisms, Biochemical Factors, and Conventional Risk Factors in Young and Elderly North Indian Patients With Acute Myocardial Infarction.
Topics: Adult; Aged; Antigens, Human Platelet; Blood Coagulation Factors; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Obesity; Polymorphism, Genetic; Risk Factors | 2016 |
Homocysteine reduces protein S-nitrosylation in endothelium.
Topics: Animals; Aorta; Endothelium, Vascular; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Male; Methionine; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein S; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Transcription Factor RelA; Vascular Cell Adhesion Molecule-1 | 2014 |
Hyperhomocysteinemia-induced oxidative stress differentially alters proteasome composition and activities in heart and aorta.
Topics: Animals; Aorta; Catalase; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Male; Malondialdehyde; Myocardium; Oxidation-Reduction; Oxidative Stress; Proteasome Endopeptidase Complex; Protein Carbonylation; Rats; Rats, Wistar; Signal Transduction; Superoxide Dismutase; Ubiquitinated Proteins; Ubiquitination | 2014 |
Protective vascular and cardiac effects of inducible nitric oxide synthase in mice with hyperhomocysteinemia.
Topics: Animals; Cerebral Arteries; Diet; Disease Models, Animal; Endothelium, Vascular; Female; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Mice; Mice, Knockout; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type II; Phenotype; Reactive Oxygen Species; Thrombosis; Vasodilator Agents | 2014 |
Hyperhomocysteinemia is a result, rather than a cause, of depression under chronic stress.
Topics: Animals; Behavior, Animal; Betaine-Homocysteine S-Methyltransferase; Chronic Disease; Depression; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats, Wistar; Recombinant Proteins; Sertraline; Stress, Psychological | 2014 |
Nutritional status of the elderly in rural North China: a cross-sectional study.
Topics: Aged; Aged, 80 and over; Body Mass Index; China; Cholesterol; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutrition Surveys; Nutritional Status; Obesity; Prevalence; Rural Health; Rural Population; Thinness; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Homocysteine promotes intestinal fibrosis in rats with trinitrobenzene sulfonic acid-induced colitis.
Topics: Animals; Colitis; Collagen Type I; Collagen Type III; Colon; Cytokines; Disease Models, Animal; Ethanol; Fibrosis; Homocysteine; Hyperhomocysteinemia; Inflammation Mediators; Intestinal Mucosa; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 2015 |
The changing of serum vitamin B12 and homocysteine levels after gastrectomy in patients with gastric cancer: do they associate with clinicopathological factors?
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Gastrectomy; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Hyperhomocysteinemia accelerates collagen accumulation in the adventitia of balloon-injured rat carotid arteries via angiotensin II type 1 receptor.
Topics: Adventitia; Angioplasty, Balloon; Animals; Carotid Artery Injuries; Collagen; Fibroblasts; Gene Expression; Homocysteine; Hyperhomocysteinemia; Male; Rats; Receptor, Angiotensin, Type 1 | 2014 |
Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase.
Topics: Angiotensin II; Animals; Binding Sites; CCCTC-Binding Factor; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; DNA Methylation; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Male; Mice, Inbred C57BL; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; S-Adenosylmethionine; Sp1 Transcription Factor; Telomerase; Telomere; Telomere Shortening; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2015 |
Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism.
Topics: Animals; Apoptosis; Betaine-Homocysteine S-Methyltransferase; Catalase; Chromatography, High Pressure Liquid; Cochlea; Female; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Glutathione Synthase; Hair Cells, Auditory; Hearing Loss; Homocysteine; Hyperhomocysteinemia; In Situ Nick-End Labeling; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidation-Reduction; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase | 2015 |
Homocysteine as a risk factor of restenosis after carotid endarterectomy.
Topics: Aged; Asymptomatic Diseases; Biomarkers; Carotid Artery, Internal; Carotid Stenosis; Endarterectomy, Carotid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Plaque, Atherosclerotic; Prospective Studies; Recurrence; Risk Factors; Saphenous Vein; Severity of Illness Index; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Duplex | 2015 |
Elevated serum homocysteine is a predictor of accelerated decline in renal function and chronic kidney disease: A historical prospective study.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Disease Progression; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Israel; Linear Models; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors; Superior Sagittal Sinus; Young Adult | 2014 |
Whey protein supplementation increases methionine intake but not homocysteine plasma concentration in rats.
Topics: Advanced Oxidation Protein Products; Animals; Biomarkers; Caseins; Dietary Supplements; Glutathione; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Liver; Male; Methionine; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Random Allocation; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Whey Proteins | 2015 |
Elevated Homocysteine Levels Are Associated With the Metabolic Syndrome and Cardiovascular Events in Hypertensive Patients.
Topics: Adult; Aged; Biomarkers; Blood Pressure; Cerebrovascular Disorders; Chi-Square Distribution; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Italy; Logistic Models; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Prevalence; Prognosis; Risk Factors; Up-Regulation | 2015 |
Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulfuration pathway in moderately vitamin B₆ deficient rats.
Topics: Animals; Asymptomatic Diseases; Biomarkers; Cystathionine; Cystathionine gamma-Lyase; Diet; Disease Models, Animal; Disease Progression; Flax; Homocysteine; Hyperhomocysteinemia; Liver; Male; Non-alcoholic Fatty Liver Disease; Proline; Pyridoxal Phosphate; Pyridoxine; Random Allocation; Rats, Sprague-Dawley; Seeds; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
[Hyperhomocysteinemia--a predictor of inflammatory changes in the liver].
Topics: Adult; Disease Progression; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-6; Liver; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Prognosis; Tumor Necrosis Factor-alpha | 2014 |
Evaluation of plasma concentrations of homocysteine, IL-6, TNF-alpha, hs-CRP, and total antioxidant capacity in patients with end-stage renal failure.
Topics: Adult; Antioxidants; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-6; Kidney Failure, Chronic; Male; Middle Aged; Oxidative Stress; Renal Dialysis; Risk Factors; Tumor Necrosis Factor-alpha | 2014 |
Mechanisms of hyperhomocysteinemia induced skeletal muscle myopathy after ischemia in the CBS-/+ mouse model.
Topics: Animals; Antioxidants; Blotting, Western; Cystathionine beta-Synthase; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Ischemia; Mice, Inbred C57BL; Models, Biological; Muscle, Skeletal; Muscular Diseases; Nitric Oxide Donors; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Protein Binding; Transcription Factors; Tyrosine | 2015 |
Prevalence of hyperhomocysteinaemia and some of its major determinants in Shaanxi Province, China: a cross-sectional study.
Topics: Adult; Aged; Aged, 80 and over; China; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutrition Surveys; Polymorphism, Genetic; Prevalence; Risk Factors; Young Adult | 2015 |
L-serine supplementation attenuates alcoholic fatty liver by enhancing homocysteine metabolism in mice and rats.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Dietary Supplements; Energy Intake; Ethanol; Fatty Liver, Alcoholic; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; S-Adenosylmethionine; Serine; Triglycerides | 2015 |
B-vitamin trials meta-analysis: less than meets the eye.
Topics: Aging; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2015 |
Homocysteine lowering, B vitamins, and cognitive aging.
Topics: Aging; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2015 |
Reply to Garrard and Jacoby and Smith et al.
Topics: Aging; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2015 |
Assessment of a possible link between hyperhomocysteinemia and hyperuricemia.
Topics: Adult; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hyperuricemia; Male; Middle Aged; Uric Acid; Young Adult | 2015 |
Plasma thiols levels in Alzheimer's disease mice under diet-induced hyperhomocysteinemia: effect of S-adenosylmethionine and superoxide-dismutase supplementation.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Chromatography; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; S-Adenosylmethionine; Sulfhydryl Compounds; Superoxide Dismutase | 2015 |
Interactions Between Nuclear Receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Blood Glucose; Cholestyramine Resin; Cholic Acid; Circadian Rhythm; Cystathionine gamma-Lyase; Diet, High-Fat; Disease Models, Animal; Ethanol; Gene Expression Regulation, Enzymologic; Glucose Intolerance; Hepatocyte Nuclear Factor 3-alpha; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Mice, Knockout; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Time Factors; Transcriptional Activation | 2015 |
[Pulmonary artery thromboembolism on the background of hyperhomocysteinemia].
Topics: Aged; Angiography; Diagnosis, Differential; Endovascular Procedures; Female; Homocysteine; Humans; Hyperhomocysteinemia; Multidetector Computed Tomography; Pulmonary Embolism; Thrombectomy; Thrombolytic Therapy; Ultrasonography, Doppler | 2015 |
Hydrogen sulfide mitigates homocysteine-mediated pathological remodeling by inducing miR-133a in cardiomyocytes.
Topics: Animals; Gene Expression Regulation; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; MEF2 Transcription Factors; Mice; MicroRNAs; Myocytes, Cardiac; Ventricular Remodeling | 2015 |
Nitrous oxide related behavioral and histopathological changes may be related to oxidative stress.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Demyelinating Diseases; Disease Models, Animal; Glutathione; Homocysteine; Hyperhomocysteinemia; Male; Motor Activity; Muscle Strength; Nitrous Oxide; Oxidative Stress; Rats, Wistar; Spinal Cord; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Dysfunction of blood pressure regulation in hyperhomocyteinemia model in rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiovascular Diseases; Disease Models, Animal; Elastic Tissue; Epinephrine; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Oxidation-Reduction; Rats, Sprague-Dawley; Risk Factors; Thiobarbiturates | 2015 |
Homocysteine thiolactone and N-homocysteinylated protein induce pro-atherogenic changes in gene expression in human vascular endothelial cells.
Topics: Atherosclerosis; Cells, Cultured; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Transcriptional Activation; Transcriptome | 2015 |
Homocysteine plasma levels in psoriasis patients: our experience and review of the literature.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Biomarkers; Case-Control Studies; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Prospective Studies; Psoriasis; Risk Factors; Young Adult | 2015 |
Frequency of hyper-homocysteinaemia in ischaemic stroke patients of Karachi.
Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Stroke | 2014 |
Homocysteine but not serum amyloid A, vitamin A and E related to increased risk of metabolic syndrome in post-menopausal Thai women.
Topics: Anthropometry; Body Mass Index; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Syndrome; Middle Aged; Odds Ratio; Postmenopause; Risk Factors; Serum Amyloid A Protein; Thailand; Vitamin A; Vitamin E | 2014 |
Selective homocysteine-lowering gene transfer attenuates pressure overload-induced cardiomyopathy via reduced oxidative stress.
Topics: Animals; Cardiomegaly; Cardiomyopathies; Cystathionine beta-Synthase; Female; Gene Transfer Techniques; Genetic Therapy; Hemodynamics; Homocysteine; Hyperhomocysteinemia; Mice, Inbred C57BL; Myocardium; Oxidative Stress | 2015 |
[The effect of miR-124 on homocysteine-induced atherosclerosis via promoter region DNA methylation in ApoE(-/-) mice].
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Diet; DNA Methylation; Foam Cells; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Promoter Regions, Genetic | 2015 |
Fitting homocysteine to disease models, as well as adjusting the models to the disease.
Topics: Animals; Cardiovascular Diseases; Disease Models, Animal; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidative Stress; Risk Factors; Signal Transduction; Vitamin B 12 | 2015 |
Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress.
Topics: Angiotensin II; Animals; Aorta; Biflavonoids; Blood Pressure; Camellia sinensis; Capillary Resistance; Catechin; Cells, Cultured; Endoplasmic Reticulum Stress; Endothelial Cells; Endothelium, Vascular; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tea; Vasodilation | 2015 |
Homocysteine facilitates LOX-1 activation and endothelial death through the PKCβ and SIRT1/HSF1 mechanism: relevance to human hyperhomocysteinaemia.
Topics: Animals; Apoptosis; Binding Sites; Cells, Cultured; DNA-Binding Proteins; Endothelial Cells; Enzyme Activation; Heat Shock Transcription Factors; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, LDL; Methionine; Mice; Mice, Inbred C57BL; NADPH Oxidases; Phosphorylation; Protein Kinase C beta; Protein Processing, Post-Translational; Reactive Oxygen Species; RNA, Messenger; Scavenger Receptors, Class E; Sirtuin 1; Transcription Factors; Up-Regulation | 2015 |
Ethnic differences in the prevalence of high homocysteine levels among low-income rural Kazakh and Uyghur adults in far western China and its implications for preventive public health.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Biomarkers; China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Poverty Areas; Prevalence; Public Health; Rural Health | 2015 |
[Betaine-enriched beet suppresses hyperhomocysteinemia induced by choline deficiency in rats].
Topics: Amino Acids; Animals; Beta vulgaris; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Choline Deficiency; Cysteine; Diet; Dietary Supplements; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Rats; Rats, Wistar | 2015 |
Homocysteine levels in schizophrenia patients newly admitted to an acute psychiatric ward.
Topics: Adult; Brief Psychiatric Rating Scale; Female; Homocysteine; Hospitalization; Humans; Hyperhomocysteinemia; Inpatients; Life Style; Male; Middle Aged; Psychiatric Department, Hospital; Schizophrenia | 2015 |
Cognitive Status According to Homocysteine and B-Group Vitamins in Elderly Adults.
Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Comorbidity; Confidence Intervals; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Odds Ratio; Prevalence; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter.
Topics: Animals; Cells, Cultured; Cystathionine gamma-Lyase; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression Regulation; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Inflammation Mediators; Macrophages; Male; Methionine; Mice; Morpholines; Organothiophosphorus Compounds; Promoter Regions, Genetic; Signal Transduction | 2015 |
Betaine prevents homocysteine-induced memory impairment via matrix metalloproteinase-9 in the frontal cortex.
Topics: Animals; Betaine; Drug Interactions; Frontal Lobe; Homocysteine; Hyperhomocysteinemia; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; Memory Disorders; Mice | 2015 |
Homocysteinemia After Hypertensive Pregnancy Disorders at Term.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Pregnancy-Induced; Linear Models; Logistic Models; Longitudinal Studies; Middle Aged; Pregnancy; Prospective Studies; Risk Factors; Time Factors | 2015 |
Pyridoxal-5'-phosphate deficiency is associated with hyperhomocysteinemia regardless of antioxidant, thiamine, riboflavin, cobalamine, and folate status in critically ill patients.
Topics: Adult; APACHE; Biomarkers; Cardiovascular Diseases; Critical Illness; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intensive Care Units; Male; Middle Aged; Nutritional Status; Oxidative Stress; Prevalence; Prospective Studies; Pyridoxal Phosphate; Risk; Spain; Vitamin B 6 Deficiency | 2016 |
Association study of methylenetetrahydrofolate reductase C677T mutation with cerebral venous thrombosis in an Iranian population.
Topics: Adolescent; Adult; Aged; Alleles; Case-Control Studies; Fasting; Female; Gene Expression; Genetic Association Studies; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Venous Thrombosis | 2015 |
Ethanol extract of Brazilian propolis ameliorates cognitive dysfunction and suppressed protein aggregations caused by hyperhomocysteinemia.
Topics: Animals; Antioxidants; Cognition Disorders; Diet; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Oxidative Stress; Propolis; Protein Aggregation, Pathological; Reactive Oxygen Species; Risk Factors | 2015 |
Metabolic interactions between hyperhomocysteinemia and endothelin-1 among Tunisian patients with acute coronary diseases.
Topics: Acute Coronary Syndrome; Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Endothelin-1; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mass Spectrometry; Middle Aged; Prospective Studies; Risk Factors; Sex Factors; Statistics as Topic; Tunisia | 2015 |
Emodin Inhibits Homocysteine-Induced C-Reactive Protein Generation in Vascular Smooth Muscle Cells by Regulating PPARγ Expression and ROS-ERK1/2/p38 Signal Pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; C-Reactive Protein; Emodin; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR gamma; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2015 |
Association of Vitamin B12 Deficiency with Homozygosity of the TT MTHFR C677T Genotype, Hyperhomocysteinemia, and Endothelial Cell Dysfunction.
Topics: Adult; Cardiovascular Diseases; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Physical Endurance; Polymorphism, Genetic; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2015 |
Hyperhomocysteinemia independently associated with the risk of hypertension: a cross-sectional study from rural China.
Topics: Adult; Age Distribution; Aged; Biomarkers; Blood Pressure; Chi-Square Distribution; China; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Prevalence; Risk Assessment; Risk Factors; Rural Health; Sex Distribution; Up-Regulation | 2016 |
Plasma Homocysteine Levels and Endothelial Dysfunction in Cerebro- and Cardiovascular Diseases in the Metabolic Syndrome.
Topics: Cerebrovascular Disorders; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Metabolic Syndrome | 2015 |
Pathological concentrations of homocysteine increases IL-1β production in macrophages in a P2X7, NF-ĸB, and erk-dependent manner.
Topics: Acetylcysteine; Animals; Antioxidants; Homocysteine; Hyperhomocysteinemia; Interleukin-1beta; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Reactive Oxygen Species; Receptors, Purinergic P2X7; Toll-Like Receptor 4 | 2015 |
Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: the role of B vitamins supplementation.
Topics: Aged; Blood Cells; Calcium; Cross-Sectional Studies; Dietary Supplements; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Telomere; Tetrahydrofolates; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D | 2016 |
Response to "Plasma Homocysteine Levels and Endothelial Dysfunction in Cerebro- and Cardiovascular Diseases in the Metabolic Syndrome".
Topics: Cerebrovascular Disorders; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Metabolic Syndrome | 2015 |
Hyperhomocysteinemia as an Early Predictor of Erectile Dysfunction: International Index of Erectile Function (IIEF) and Penile Doppler Ultrasound Correlation With Plasma Levels of Homocysteine.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Erectile Dysfunction; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Middle Aged; Penis; Risk Factors; Severity of Illness Index; Ultrasonography, Doppler | 2015 |
Individual and Joint Associations of Methylenetetrahydrofolate Reductase C677T Genotype and Plasma Homocysteine With Dyslipidemia in a Chinese Population With Hypertension.
Topics: Asian People; Cholesterol, LDL; Dyslipidemias; Essential Hypertension; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Methylenetetrahydrofolate Reductase (NADPH2) | 2017 |
Hyperhomocysteinemia is associated with severity of cirrhosis and negative impact after liver transplantation.
Topics: Adolescent; Adult; Aged; Alberta; Female; Graft Survival; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis; Liver Transplantation; Logistic Models; Male; Middle Aged; Multivariate Analysis; Risk Factors; ROC Curve; Severity of Illness Index; Thrombosis; Young Adult | 2016 |
High homocysteine, low vitamin B-6, and increased oxidative stress are independently associated with the risk of chronic kidney disease.
Topics: Adult; Aged; Antioxidants; Case-Control Studies; Female; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Pyridoxal Phosphate; Renal Insufficiency, Chronic; Risk Factors; Superoxide Dismutase; Vitamin B 6; Vitamin B 6 Deficiency | 2016 |
The Structural Alteration and Aggregation of Bovine Lens Gamma-Crystallin by Homocysteinylation; The Pathomechanism Underlying Cataract Development During Hyperhomocysteinimia.
Topics: Animals; Cataract; Cattle; Circular Dichroism; Disulfides; gamma-Crystallins; Homocysteine; Hydrophobic and Hydrophilic Interactions; Hyperhomocysteinemia; Lens, Crystalline; Protein Aggregates | 2016 |
Hyperhomocysteinemia predicts renal function decline: a prospective study in hypertensive adults.
Topics: Aged; Blood Pressure; Cohort Studies; Demography; Female; Folic Acid; Follow-Up Studies; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney; Male; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors; Vitamin B 12 | 2015 |
Homocysteine in Chronic Heart Failure.
Topics: Adult; Aged; Biomarkers; Comorbidity; Female; Follow-Up Studies; France; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Kidney Diseases; Male; Middle Aged; Natriuretic Peptide, Brain; Oxidative Stress; Oxygen Consumption; Prognosis; Proportional Hazards Models; Risk Factors; Young Adult | 2015 |
Hyperhomocysteinemia and high doses of nilotinib favor cardiovascular events in chronic phase Chronic Myelogenous Leukemia patients.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Cholesterol, HDL; Coronary Artery Disease; Drug Administration Schedule; Female; Homocysteine; Humans; Hyperhomocysteinemia; Imatinib Mesylate; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Prospective Studies; Pyrimidines; Retrospective Studies; Triglycerides | 2016 |
Homocysteine-lowering therapy and early functional outcomes of ischemic patients with H-type hypertension: a retrospective analysis of CNSR.
Topics: Aged; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Prognosis; Stroke; Treatment Outcome | 2015 |
Plasma homocysteine levels, methylene tetrahydrofolate reductase A1298C gene polymorphism and risk of retinal vein thrombosis.
Topics: Adult; Aged; Alleles; Case-Control Studies; Fasting; Female; Gene Expression; Gene Frequency; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Retinal Vein Occlusion; Risk Factors | 2016 |
N- and S-homocysteinylation reduce the binding of human serum albumin to catechins.
Topics: Aminoacylation; Catechin; Cysteine; Electrophoresis, Capillary; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Ligands; Lysine; Protein Processing, Post-Translational; Serum Albumin; Serum Albumin, Human | 2017 |
Severe Hyperhomocysteinemia Decreases Respiratory Enzyme and Na(+)-K(+) ATPase Activities, and Leads to Mitochondrial Alterations in Rat Amygdala.
Topics: Amygdala; Animals; Apoptosis; Creatine; Electron Transport Chain Complex Proteins; Electron Transport Complex IV; Female; Homocysteine; Hyperhomocysteinemia; Male; Mitochondria; Necrosis; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Succinate Dehydrogenase | 2016 |
Placental NRP1 and VEGF expression in pre-eclamptic women and in a homocysteine-treated mouse model of pre-eclampsia.
Topics: Adult; Animals; Disease Models, Animal; Female; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Neuropilin-1; Placenta; Pre-Eclampsia; Pregnancy; Vascular Endothelial Growth Factor A | 2016 |
Hyperhomocysteinaemia as a potential marker of early renal function decline in middle-aged Asian people without chronic kidney disease.
Topics: Adult; Age Factors; Biomarkers; Cross-Sectional Studies; Female; Follow-Up Studies; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Function Tests; Male; Middle Aged; Renal Insufficiency, Chronic; Republic of Korea; Retrospective Studies; Time Factors | 2016 |
Molecular and biochemical investigations of patients with intermediate or severe hyperhomocysteinemia.
Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Bone Density; Cystathionine beta-Synthase; Denmark; Female; Follow-Up Studies; Genotype; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymorphism, Genetic; Prevalence; Thromboembolism; Young Adult | 2016 |
Adenosine plasma level correlates with homocysteine and uric acid concentrations in patients with coronary artery disease.
Topics: Adenosine; Aged; Case-Control Studies; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Tumor Cells, Cultured; Uric Acid | 2016 |
Combination of hyperhomocysteinemia and ischemic tolerance in experimental model of global ischemia in rats.
Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Ischemic Preconditioning; Male; Mitogen-Activated Protein Kinases; Rats, Wistar | 2015 |
High homocysteine and epistasis between MTHFR and APOE: association with cognitive performance in the elderly.
Topics: Age Factors; Aged; Aging; Apolipoproteins E; Biomarkers; Cognition; Cognition Disorders; Cross-Sectional Studies; Epistasis, Genetic; Executive Function; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Phenotype; Polymorphism, Genetic; Principal Component Analysis; Risk Factors; Up-Regulation | 2016 |
Acute Myocardial Infarction in a Young Man with Hyperhomocysteinemia and Pulmonary Tuberculosis.
Topics: Acute Disease; Adult; Chest Pain; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Risk Factors; Tuberculosis, Pulmonary; Vitamin B Complex | 2016 |
Impact of Diabetes on Homocysteine Levels and Its Relationship with Coronary Artery Disease: A Single-Centre Cohort Study.
Topics: Age Factors; Aged; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Diabetic Angiopathies; Diabetic Cardiomyopathies; Diabetic Nephropathies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Hypertriglyceridemia; Italy; Male; Middle Aged; Prevalence; Renal Insufficiency; Risk Factors; Severity of Illness Index; Smoking | 2016 |
Combined Effect of Hyperhomocysteinemia and Hypertension on the Presence of Early Carotid Artery Atherosclerosis.
Topics: Aged; Biomarkers; Blood Pressure; Carotid Artery Diseases; Carotid Artery, Common; Carotid Intima-Media Thickness; China; Early Diagnosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Logistic Models; Male; Middle Aged; Odds Ratio; Plaque, Atherosclerotic; Predictive Value of Tests; Prevalence; Protective Factors; Risk Factors; Severity of Illness Index; Up-Regulation | 2016 |
Atorvastatin attenuates atherosclerotic plaque destabilization by inhibiting endoplasmic reticulum stress in hyperhomocysteinemic mice.
Topics: Animals; Aorta; Apolipoproteins E; Atorvastatin; Blotting, Western; Down-Regulation; Endoplasmic Reticulum Stress; Homocysteine; Hyperhomocysteinemia; Macrophages; Male; Matrix Metalloproteinase 9; Methionine; Mice; Mice, Knockout; Plaque, Atherosclerotic; RAW 264.7 Cells; Real-Time Polymerase Chain Reaction; Thapsigargin; Tumor Necrosis Factor-alpha | 2016 |
Homocysteinemia is Associated with a Lower Degree of PBMC LINE-1 Methylation and a Higher Risk of CIN 2C in the U.S. Post-Folic Acid Fortification Era.
Topics: Adult; Body Mass Index; Contraceptives, Oral, Hormonal; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leukocytes, Mononuclear; Logistic Models; Long Interspersed Nucleotide Elements; Middle Aged; Papillomavirus Infections; Risk Factors; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Young Adult | 2016 |
Increased neutrophil to lymphocyte ratio in persons suffering from hypertension with hyperhomocysteinemia.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Cholesterol; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lymphocytes; Male; Middle Aged; Neutrophils; Retrospective Studies; Risk Factors; Triglycerides | 2016 |
Related factors of serum uric acid in patients with primary hypertension and hyperhomocysteinemia.
Topics: Adult; Aged; Blood Glucose; China; Cholesterol; Creatinine; Cross-Sectional Studies; Essential Hypertension; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Risk Factors; Triglycerides; Uric Acid | 2016 |
High homocysteine levels prevent via H2 S the CoCl2 -induced alteration of lymphocyte viability.
Topics: Adenosine; Adult; Alkynes; Cell Hypoxia; Cell Survival; Cobalt; Glycine; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Lymphocytes; Middle Aged; Models, Biological; Signal Transduction | 2016 |
Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis.
Topics: Aged; Carcinoma, Hepatocellular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis; Liver Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Portal Vein; Retrospective Studies; Venous Thrombosis | 2016 |
Serum levels of homocysteine, asymmetric dimethylarginine and nitric oxide in patients with Parkinson's disease.
Topics: Aged; Arginine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Male; Middle Aged; Nitric Oxide; Parkinson Disease | 2016 |
Metabolic dysregulation in first-episode schizophrenia patients with respect to genetic variation in one-carbon metabolism.
Topics: Adult; Betaine-Homocysteine S-Methyltransferase; Blood Glucose; Carbon; Case-Control Studies; Dyslipidemias; Fasting; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Male; Metabolic Syndrome; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Minor Histocompatibility Antigens; One-Carbon Group Transferases; Polymorphism, Genetic; Prevalence; Psychotic Disorders; Schizophrenia; Triglycerides; Vitamin B 12; Young Adult | 2016 |
Comparative case-control study of homocysteine, vitamin B
Topics: Adult; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Case-Control Studies; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B 12 | 2017 |
Homocysteinemia and early outcome of acute ischemic stroke in elderly patients.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Outcome Assessment, Health Care; Stroke | 2016 |
Increased homocysteine and lipoprotein(a) levels highlight systemic atherosclerotic burden in patients with a history of acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aged; Ankle Brachial Index; Atherosclerosis; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thickness; Chi-Square Distribution; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Lipoprotein(a); Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Predictive Value of Tests; Prognosis; Pulse Wave Analysis; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Ultrasonography, Doppler; Up-Regulation | 2016 |
Berberine activates peroxisome proliferator-activated receptor gamma to increase atherosclerotic plaque stability in Apoe
Topics: Animals; Apolipoproteins E; Berberine; Carotid Arteries; Cell Survival; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Homocysteine; Hyperhomocysteinemia; Male; Mice; Mice, Knockout; Oxidative Stress; Plaque, Atherosclerotic; PPAR gamma | 2016 |
Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes.
Topics: Animals; Arachidonic Acids; Celecoxib; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Endocannabinoids; Homocysteine; Hyperhomocysteinemia; Inflammasomes; Male; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Podocytes; Polyunsaturated Alkamides | 2016 |
Impact of Dyrk1A level on alcohol metabolism.
Topics: Alanine Transaminase; Animals; Aryldialkylphosphatase; Cystathionine beta-Synthase; Disease Models, Animal; Dyrk Kinases; Ethanol; Female; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NAD(P)H Dehydrogenase (Quinone); Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Triglycerides; Up-Regulation | 2016 |
Dietary diversity no longer offsets the mortality risk of hyperhomocysteinaemia in older adults with diabetes: a prospective cohort study.
Topics: Aged; Anthropometry; Biomarkers; Cohort Studies; Comorbidity; Diabetes Mellitus; Diet; Female; Health Status; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Prospective Studies; Risk Factors; Sex Distribution; Taiwan; Vitamin B Complex | 2016 |
Hepatoprotective effects of lycopene on liver enzymes involved in methionine and xenobiotic metabolism in hyperhomocysteinemic rats.
Topics: Adenosylhomocysteinase; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Carotenoids; Cystathionine beta-Synthase; Diet; Homocysteine; Hyperhomocysteinemia; Liver; Liver Diseases; Lycopene; Male; Malondialdehyde; Methionine; Oxidative Stress; Rats; Rats, Wistar | 2016 |
Daytime sleepiness is associated with hyperhomocysteinemia in rural area of China: A cross-sectional study.
Topics: Adult; Aged; Apnea; China; Coronary Disease; Cross-Sectional Studies; Disorders of Excessive Somnolence; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Risk Factors; Sex Factors; Sleep; Snoring; Stroke; Surveys and Questionnaires | 2016 |
The effect of levodopa benserazide hydrochloride on homocysteinemia levels in patients with Parkinson's disease and treatment of hyperhomocysteinemia.
Topics: Antiparkinson Agents; Benserazide; Dopamine Agents; Drug Combinations; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Parkinson Disease | 2016 |
Prevalence of Homocysteine-Related Hypertension in Patients With Chronic Kidney Disease.
Topics: Adolescent; Adult; Aged; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Linear Models; Male; Middle Aged; Renal Insufficiency, Chronic; Serum Albumin; Uric Acid; Young Adult | 2017 |
Homocysteine diminishes apolipoprotein A-I function and expression in patients with hypothyroidism: a cross-sectional study.
Topics: Adult; Apolipoprotein A-I; Cholesterol, HDL; Cross-Sectional Studies; Female; Gene Expression; Homocysteine; Humans; Hyperhomocysteinemia; Hypothyroidism; Insulin Resistance; Male; Middle Aged; Risk Factors | 2016 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
Vitamin B12 status in women of childbearing age in the UK and its relationship with national nutrient intake guidelines: results from two National Diet and Nutrition Surveys.
Topics: Adult; Cross-Sectional Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Malnutrition; Nutrition Policy; Nutrition Surveys; Prevalence; United Kingdom; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
N-Homocysteinylation impairs collagen cross-linking in cystathionine β-synthase-deficient mice: a novel mechanism of connective tissue abnormalities.
Topics: Animals; Collagen Type I; Collagen Type I, alpha 1 Chain; Connective Tissue; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Lysine; Mice, Knockout; Peptides | 2016 |
[Association of Crohn's disease with transcobalamin Ⅱ gene polymorphisms and serum homocysteine, folate and vitamin B12 levels in Chinese patients].
Topics: Alleles; Crohn Disease; Folic Acid; Folic Acid Deficiency; Genotype; Haplotypes; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Mutation; Polymorphism, Genetic; Prevalence; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Independent Correlation of Serum Homocysteine with Cerebral Microbleeds in Patients with Acute Ischemic Stroke due to Large-Artery Atherosclerosis.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Cerebral Hemorrhage; China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Magnetic Resonance Imaging; Male; Middle Aged; Prognosis; Risk Factors; Severity of Illness Index; Stroke; Up-Regulation | 2016 |
Comparison of Protein N-Homocysteinylation in Rat Plasma under Elevated Homocysteine Using a Specific Chemical Labeling Method.
Topics: Animals; Blood Proteins; Homocysteine; Hyperhomocysteinemia; Plasma; Protein Processing, Post-Translational; Rats; Vitamin B 12 Deficiency | 2016 |
Upregulation of DAPK contributes to homocysteine-induced endothelial apoptosis via the modulation of Bcl2/Bax and activation of caspase 3.
Topics: Apoptosis; Atherosclerosis; bcl-2-Associated X Protein; Caspase 3; Death-Associated Protein Kinases; Endothelium; Gene Expression Regulation; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger | 2016 |
Clinical significance of hyperhomocysteinemia in infective endocarditis: A case-control study.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Endocarditis; Female; Heart Valve Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Prevalence; Young Adult | 2016 |
Lower serum B12 vitamin concentrations are not accompanied by hyperhomocysteinaemia in chronic spontaneous urticaria.
Topics: Adult; Atherosclerosis; Biomarkers; C-Reactive Protein; Chronic Disease; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Immunoturbidimetry; Luminescent Measurements; Male; Severity of Illness Index; Time Factors; Urticaria; Vitamin B 12 | 2017 |
Evaluation of Homocysteine, Vitamin B12 and Folic Acid Levels During all the Trimesters in Pregnant and Preeclamptic Womens.
Topics: Case-Control Studies; Female; Fetal Blood; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Pregnancy Trimesters; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Serum folate predicts muscle strength: a pilot cross-sectional study of the association between serum vitamin levels and muscle strength and gait measures in patients >65 years old with diabetes mellitus in a primary care setting.
Topics: Accidental Falls; Aged; Cross-Sectional Studies; Diabetes Mellitus; Female; Folic Acid; Folic Acid Deficiency; Gait; Hand Strength; Homocysteine; Humans; Hyperhomocysteinemia; Male; Muscle Strength; Pilot Projects; Primary Health Care; Risk Factors; Singapore; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D; Vitamin D Deficiency | 2016 |
High Prevalence of Hyperhomocysteinemia and Its Association with Target Organ Damage in Chinese Patients with Chronic Kidney Disease.
Topics: Adult; Calcium Phosphates; Carotid Arteries; Carotid Intima-Media Thickness; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Hypertrophy, Left Ventricular; Incidence; Kidney; Linear Models; Male; Middle Aged; Prevalence; Renal Insufficiency, Chronic; Risk Factors; Serum Albumin; Sex Factors; Uric Acid; Ventricular Dysfunction, Left | 2016 |
Homocysteine metabolism in children and adolescents with epidermolysis bullosa.
Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Child, Preschool; Epidermolysis Bullosa; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Linear Models; Male; Severity of Illness Index; Young Adult | 2016 |
Hyperhomocysteinemia increases the risk of chronic kidney disease in a Chinese middle-aged and elderly population-based cohort.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; China; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Proteinuria; Renal Insufficiency, Chronic; Risk Factors | 2017 |
Associations between homocysteine metabolism related SNPs and carotid intima-media thickness: a Chinese sib pair study.
Topics: Asian People; Atherosclerosis; Carotid Artery, Common; Carotid Intima-Media Thickness; Coronary Artery Disease; Epistasis, Genetic; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Polymorphism, Single Nucleotide; Siblings | 2017 |
Is hyperhomocysteinemia a causal factor for heart failure? The impact of the functional variants of MTHFR and PON1 on ischemic and non-ischemic etiology.
Topics: Aged; Aryldialkylphosphatase; Cardiomyopathy, Dilated; Causality; Female; Genetic Predisposition to Disease; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Ischemia; Poland; Risk Factors; Stroke Volume | 2017 |
Therapeutic Potential of Progranulin in Hyperhomocysteinemia-Induced Cardiorenal Dysfunction.
Topics: Animals; Cardio-Renal Syndrome; Disease Models, Animal; Echocardiography; Granulins; Homocysteine; Hyperhomocysteinemia; Intercellular Signaling Peptides and Proteins; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Progranulins; Recombinant Proteins | 2017 |
Homocysteine modulates 5-lipoxygenase expression level via DNA methylation.
Topics: Amyloid beta-Peptides; Animals; Arachidonate 5-Lipoxygenase; Brain; Diet; DNA Methylation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mice; Neurons; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic | 2017 |
Effects of fisetin on hyperhomocysteinemia-induced experimental endothelial dysfunction and vascular dementia.
Topics: Acetylcholinesterase; Animals; Aorta; Brain; Catalase; Cholesterol; Dementia, Vascular; Donepezil; Dose-Response Relationship, Drug; Endothelium, Vascular; Flavonoids; Flavonols; Glutathione; Homocysteine; Hyperhomocysteinemia; Indans; Lipid Peroxidation; Male; Maze Learning; Methionine; Necrosis; Nitric Oxide; Nitrites; Piperidines; Rats; Superoxide Dismutase | 2017 |
Homocysteine Activates B Cells via Regulating PKM2-Dependent Metabolic Reprogramming.
Topics: Animals; Atherosclerosis; B-Lymphocytes; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Knockdown Techniques; Homocysteine; Hyperhomocysteinemia; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Pyruvate Kinase; Tandem Mass Spectrometry | 2017 |
Hyperhomocysteinemia in ApoE-/- Mice Leads to Overexpression of Enhancer of Zeste Homolog 2 via miR-92a Regulation.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cell Line; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Deletion; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Up-Regulation | 2016 |
Increased Coagulation With Aging: Importance of Homocysteine and Vitamin B12.
Topics: Adult; Aged; Aged, 80 and over; Aging; Atrial Fibrillation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Thrombophilia; Vitamin B 12 | 2017 |
Increased Coagulation With Aging: Importance of Homocysteine and Vitamin B12 - Reply.
Topics: Aging; Homocysteine; Humans; Hyperhomocysteinemia; Thrombophilia; Vitamin B 12 | 2017 |
Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation.
Topics: Adult; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; DNA Methylation; Eicosanoids; Female; Hep G2 Cells; Homocysteine; Humans; Hyperhomocysteinemia; Immunohistochemistry; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transplantation, Heterologous | 2017 |
Testing for homocysteine in clinical practice.
Topics: Alzheimer Disease; Blood Chemical Analysis; Cardiovascular Diseases; Cognition Disorders; Delivery of Health Care; Homocysteine; Humans; Hyperhomocysteinemia; Practice Patterns, Physicians' | 2017 |
Contribution of guanine nucleotide exchange factor Vav2 to NLRP3 inflammasome activation in mouse podocytes during hyperhomocysteinemia.
Topics: Animals; CARD Signaling Adaptor Proteins; Disease Models, Animal; Homocysteine; Humans; Hyperhomocysteinemia; Inflammasomes; Kidney Glomerulus; Mice; Neuropeptides; NLR Family, Pyrin Domain-Containing 3 Protein; Podocytes; Proto-Oncogene Proteins c-vav; rac1 GTP-Binding Protein; Reactive Oxygen Species; RNA, Small Interfering | 2017 |
Hyperhomocysteinemia Exacerbates Cisplatin-induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Line; Cell Proliferation; Cisplatin; Endoplasmic Reticulum Stress; Homocysteine; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Rats | 2017 |
Association between hyperhomocysteinemia and stroke with atherosclerosis and small artery occlusion depends on homocysteine metabolism-related vitamin levels in Chinese patients with normal renal function.
Topics: Aged; Aged, 80 and over; Asian People; Case-Control Studies; Cerebrovascular Disorders; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Kidney; Male; Middle Aged; Retrospective Studies; Stroke; Vitamin B 12 | 2017 |
Folate Deficiency and Gene Polymorphisms of MTHFR, MTR and MTRR Elevate the Hyperhomocysteinemia Risk.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors | 2017 |
Elevated Plasma Homocysteine Level Increased the Risk of Early Renal Impairment in Acute Ischemic Stroke Patients.
Topics: Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Case-Control Studies; China; Cystatin C; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Middle Aged; Retrospective Studies; Risk Factors; Stroke | 2017 |
Effect of lyophilized prune extract on hyperhomocysteinemia in mice.
Topics: Adenosylhomocysteinase; Animals; Chlorogenic Acid; Cystathionine beta-Synthase; Female; Freeze Drying; Homocysteine; Hyperhomocysteinemia; Male; Mice, Inbred C57BL; Mice, Mutant Strains; NAD(P)H Dehydrogenase (Quinone); Plant Extracts; Prunus domestica | 2017 |
Pilot study of homocysteine and cysteine in patients with thrombosis in different vascular sites. Epidemiology and response to folate.
Topics: Adult; Aged; Cysteine; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pilot Projects; Thrombosis; Vitamin B 12 | 2009 |
Homocysteine levels in patients with deep vein thrombosis lacking thrombophilic defects.
Topics: Adult; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Assessment; Risk Factors; Thrombophilia; Venous Thrombosis | 2008 |
Changes in predictors and status of homocysteine in young male adults after a dietary intervention with vegetables, fruits and bread.
Topics: Adolescent; Adult; Bread; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Norway; Riboflavin; Surveys and Questionnaires; Treatment Outcome; Vegetables; Vitamin B 12; Vitamin B Complex | 2008 |
Effects of hyperhomocysteinemia on non-adrenergic non-cholinergic relaxation in isolated rat duodenum.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Disease Models, Animal; Duodenum; Electric Stimulation; Enteric Nervous System; Enzyme Inhibitors; Epinephrine; gamma-Aminobutyric Acid; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sulfathiazoles | 2008 |
Homocysteinemia in hypertensive patients with renal target organ damage (mild renal dysfunction).
Topics: Adult; Aged; Cardiovascular Diseases; Creatinine; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged | 2008 |
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents | 2008 |
Association of hyperhomocysteinemia and Chlamydia pneumoniae infection with carotid atherosclerosis and coronary artery disease in Japanese patients.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Bacterial; Carotid Artery Diseases; Case-Control Studies; Chlamydia Infections; Chlamydophila pneumoniae; Coronary Artery Disease; Cross-Sectional Studies; Female; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Immunoglobulin G; Japan; Male; Middle Aged | 2008 |
Clinical usefulness of a HPLC method for simultaneous quantitation of plasma homocysteine and cysteine.
Topics: Adult; Chromatography, High Pressure Liquid; Cysteine; Diet, Vegetarian; Female; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Male; Middle Aged; Nutritional Status; Time Factors | 2008 |
Metformin, B12 and homocysteine levels: the plausible cause or effect?
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Metformin; Venous Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
High plasma homocysteine is associated with the risk of coronary artery disease independent of methylenetetrahydrofolate reductase 677C-->T genotypes.
Topics: Alleles; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Effects of various amino acids on methionine-induced hyperhomocysteinemia in rats.
Topics: Amino Acids; Animals; Arginine; Dietary Supplements; Glutamic Acid; Histidine; Homocysteine; Hyperhomocysteinemia; Methionine; Rats | 2008 |
Hyperhomocysteinemia induced by guanidinoacetic acid is effectively suppressed by choline and betaine in rats.
Topics: Animals; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Glycine; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Rats | 2008 |
[Effect of polymorphisms on key enzymes in homocysteine metabolism, on plasma homocysteine level and on coronary artery-disease risk in a Tunisian population].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Coronary Stenosis; Cystathionine beta-Synthase; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Tunisia | 2008 |
Exploratory study of plasma total homocysteine and its relationship to short-term outcome in acute ischaemic stroke in Nigerians.
Topics: Aged; Black People; Case-Control Studies; Diabetes Complications; Female; Fluorescence Polarization Immunoassay; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Ischemia; Male; Middle Aged; Nigeria; Outcome Assessment, Health Care; Prevalence; Prospective Studies; Regression Analysis; Risk Factors; Severity of Illness Index; Smoking; Stroke; Survival Rate | 2008 |
[Hypermethylation of estrogen receptor-alpha gene and high homocysteine in atheromatosis patients].
Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; CpG Islands; DNA Methylation; Estrogen Receptor alpha; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Promoter Regions, Genetic | 2008 |
Effects of red wine polyphenolic compounds on paraoxonase-1 and lectin-like oxidized low-density lipoprotein receptor-1 in hyperhomocysteinemic mice.
Topics: Animals; Antioxidants; Aorta; Aryldialkylphosphatase; Biomarkers; Caffeic Acids; Cystathionine beta-Synthase; Disease Models, Animal; Female; Flavonoids; Gene Expression Regulation, Enzymologic; Heterozygote; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Phenols; Polyphenols; Receptors, Oxidized LDL; Wine | 2009 |
The correlation of plasma homocysteine with insulin resistance in polycystic ovary syndrome.
Topics: Adult; Blood Glucose; Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infertility, Female; Insulin; Insulin Resistance; Polycystic Ovary Syndrome; Turkey | 2008 |
Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2-dependent cyclin E expression.
Topics: Adult Stem Cells; Aged; Aged, 80 and over; Animals; Cell Proliferation; Cells, Cultured; Cognition Disorders; Cyclin E; Dementia; Dentate Gyrus; Disease Models, Animal; Fibroblast Growth Factor 2; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurodegenerative Diseases; Neurons; Trigeminal Caudal Nucleus | 2008 |
Homocysteine and stroke prevention: have the trials settled the issue?
Topics: Clinical Trials as Topic; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamins | 2006 |
Vitamin B12 and homocysteine status in asymptomatic Indian toddlers.
Topics: Body Height; Body Weight; Child, Preschool; Comorbidity; Cross-Sectional Studies; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Prevalence; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Homocysteine reduces endothelial progenitor cells in stroke patients through apoptosis.
Topics: Apoptosis; Caspase 3; Caspase 8; Cells, Cultured; Cytochromes c; Endothelial Cells; Enzyme Activation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stem Cells; Stroke; Vitamins | 2009 |
Serum homocysteine in pre-eclampsia and eclampsia.
Topics: Adult; Bangladesh; Case-Control Studies; Eclampsia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Pilot Projects; Pre-Eclampsia; Pregnancy; Risk Factors | 2008 |
Homocysteine is not so paradoxical.
Topics: Animals; Cardiovascular Diseases; Copper; Dietary Supplements; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2008 |
Folate deprivation, the methionine cycle, and Alzheimer's disease.
Topics: Alzheimer Disease; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Methionine | 2008 |
Protective effect of Embelia ribes Burm on methionine-induced hyperhomocysteinemia and oxidative stress in rat brain.
Topics: Animals; Brain; Cholesterol; Embelia; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Triglycerides | 2008 |
[Nitric oxide synthetase and carbon monoxide decrease in the penile corpus cavernous of hyper homocysteine rats].
Topics: Animals; Carbon Monoxide; Homocysteine; Hyperhomocysteinemia; Male; Nitric Oxide Synthase; Penis; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet | 2008 |
Should plasma homocysteine be used as a biomarker of venous thromboembolism? A case-control study.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Prevalence; Prospective Studies; Risk Factors; Ultrasonography; Venous Thromboembolism; Young Adult | 2009 |
Associations between serum selenium and total plasma homocysteine during the acute phase of ischaemic stroke.
Topics: Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Plasma; Selenium; Stroke | 2008 |
Homocysteine enhances cell proliferation in hepatic myofibroblastic stellate cells.
Topics: Animals; Cell Proliferation; Hepatic Stellate Cells; Homocysteine; Hyperhomocysteinemia; Liver Cirrhosis; Male; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2009 |
Ras proteins, nitrosylation and homocysteine metabolism.
Topics: Genes, ras; Homocysteine; Humans; Hyperhomocysteinemia; NF-kappa B; Nitrogen Oxides; Pheochromocytoma; ras Proteins | 2008 |
Free flap failure secondary to dual thrombophilia.
Topics: Factor VIII; Graft Survival; Homocysteine; Humans; Hyperhomocysteinemia; Leg; Male; Microsurgery; Middle Aged; Plastic Surgery Procedures; Postoperative Complications; Surgical Flaps; Thrombophilia; Thrombosis; Ultrasonography, Doppler | 2009 |
Study on homocysteine levels and methylenetetrahydrofolate reductase gene variant (C677T) in a population of Buenos Aires City.
Topics: Adolescent; Adult; Aged; Alleles; Argentina; Base Sequence; Cross-Sectional Studies; DNA Primers; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Vascular Diseases; Young Adult | 2008 |
[The importance of homocysteinemia measurement in chronic renal failure].
Topics: Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged | 2007 |
Effect of anti-oxidant treatment on hyperhomocysteinemia-induced myocardial fibrosis and diastolic dysfunction.
Topics: Animals; Antioxidants; Ascorbic Acid; Body Weight; Collagen; Coronary Vessels; Diastole; Endomyocardial Fibrosis; Heart; Homocysteine; Hyperhomocysteinemia; Male; Organ Size; Rats; Rats, Sprague-Dawley; Vitamin E | 2008 |
A study of changes in homocysteine levels during normal pregnancy and pre-eclampsia.
Topics: Adolescent; Adult; Case-Control Studies; Cross-Sectional Studies; Female; Fluorescence Polarization; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Welfare; Perinatal Care; Pre-Eclampsia; Pregnancy; Risk Factors; Young Adult | 2008 |
B-vitamins, homocysteine and gene polymorphism in adults with fasting or post-methionine loading hyperhomocysteinemia.
Topics: Adult; Cross-Sectional Studies; Fasting; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B Complex | 2008 |
Chronic hyperhomocysteinemia alters antioxidant defenses and increases DNA damage in brain and blood of rats: protective effect of folic acid.
Topics: Animals; Antioxidants; Catalase; DNA; DNA Damage; Folic Acid; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Micronucleus Tests; Parietal Lobe; Rats; Rats, Wistar | 2009 |
Is ischemic stroke risk related to folate status or other nutrients correlated with folate intake?
Topics: Adult; Aged; Aged, 80 and over; Blood Proteins; Brain Ischemia; Diet; Feeding Behavior; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Life Style; Male; Micronutrients; Middle Aged; Nutritional Requirements; Risk Factors; Sampling Studies; Surveys and Questionnaires; Taiwan | 2008 |
Homocysteine: the Rubik's cube of cardiovascular risk factors.
Topics: Atherosclerosis; Biomarkers; Coronary Disease; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Hypertension; Inflammation Mediators; Myocardial Infarction; Platelet Activation; Research Design; Risk Assessment; Risk Factors; Smoking; Stroke; Vascular Cell Adhesion Molecule-1; Vitamin B Complex | 2008 |
Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats.
Topics: Animals; Disease Models, Animal; Extracellular Matrix; Folic Acid; Homocysteine; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Glomerulus; Matrix Metalloproteinases; NADPH Oxidases; Oxidative Stress; Proto-Oncogene Proteins c-vav; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; RNA; Sclerosis; Superoxides; Tissue Inhibitor of Metalloproteinase-1; Transfection | 2009 |
Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population.
Topics: Acute Disease; Asian People; Brain Ischemia; DNA Mutational Analysis; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitric Oxide Synthase Type III; Nitrites; Polymorphism, Genetic; Singapore; Stroke | 2008 |
Methionine supplementation accelerates oxidative stress and nuclear factor kappaB activation in livers of C57BL/6 mice.
Topics: Animals; Antioxidants; Cholesterol; Dietary Supplements; Enzymes; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Oxidoreductases; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Triglycerides | 2008 |
Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone.
Topics: Aged; Animals; Bone and Bones; Collagen; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methionine; Myocardium; Osteoporosis; Porosity; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Stress, Mechanical | 2009 |
High-casein diet suppresses guanidinoacetic acid-induced hyperhomocysteinemia and potentiates the hypohomocysteinemic effect of serine in rats.
Topics: Animals; Caseins; Cysteine; Diet; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2008 |
Association of homocysteinemia with high concentrations of serum insulin and uric acid in Brazilian subjects with metabolic syndrome genotyped for C677T polymorphism in the methylenetetrahydrofolate reductase gene.
Topics: Adult; Body Mass Index; Brazil; Cross-Sectional Studies; Female; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Logistic Models; Male; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Uric Acid; Vitamin B 12 Deficiency | 2008 |
Hemolysis and hyperhomocysteinemia caused by cobalamin deficiency: three case reports and review of the literature.
Topics: Aged, 80 and over; Anemia, Hemolytic; Erythrocyte Transfusion; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Lowering homocysteine with B vitamins in patients with coronary artery disease.
Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2008 |
Lowering homocysteine with B vitamins in patients with coronary artery disease.
Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2008 |
Lowering homocysteine with B vitamins in patients with coronary artery disease.
Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2008 |
Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss.
Topics: Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; DNA Damage; Embryo Loss; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Micronuclei, Chromosome-Defective; Parents; Polymorphism, Single Nucleotide; Pregnancy; Recurrence; Young Adult | 2009 |
Hyperhomocysteinemia in patients with epilepsy: does it play a role in the pathogenesis of brain atrophy? A preliminary report.
Topics: Adolescent; Adult; Atrophy; Brain; Epilepsy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Oxidative Stress | 2009 |
Hyperhomocysteinaemia in HIV-infected patients: determinants of variability and correlations with predictors of cardiovascular disease.
Topics: Adult; Anthropometry; Antiretroviral Therapy, Highly Active; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Female; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolic Syndrome; Predictive Value of Tests; Prospective Studies; Risk Assessment | 2009 |
Homocysteine promotes proliferation and activation of microglia.
Topics: Animals; Animals, Newborn; Cell Proliferation; Cells, Cultured; DNA Replication; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Inbred BALB C; Microglia; NADPH Oxidases; Reactive Oxygen Species; Up-Regulation | 2010 |
Plasma homocysteine, MTHFR gene mutation, and open-angle glaucoma.
Topics: Aged; Cross-Sectional Studies; Exfoliation Syndrome; Female; Fluorescence Polarization Immunoassay; Glaucoma, Open-Angle; Homocysteine; Humans; Hyperhomocysteinemia; Intraocular Pressure; Male; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Polymerase Chain Reaction; Prospective Studies | 2009 |
[Homocysteine and its role in clinical practice (a lecture)].
Topics: Biomarkers; Clinical Chemistry Tests; Diabetes Mellitus; Female; Gastrointestinal Diseases; History, 20th Century; History, 21st Century; Homocysteine; Humans; Hyperhomocysteinemia; Hyperthyroidism; Kidney Diseases; Mental Disorders; Osteoporosis; Pregnancy; Pregnancy Complications, Cardiovascular | 2008 |
Prenatal hyperhomocysteinemia as a model of oxidative stress of the brain.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Cognition; Female; Fetus; Homocysteine; Hyperhomocysteinemia; Maze Learning; N-Methylaspartate; Oxidative Stress; Pregnancy; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2008 |
[Estimation of relation between homocysteine concentration and selected lipid parameters and adhesion molecules concentration in children with atherosclerosis risk factors].
Topics: Adolescent; Atherosclerosis; Biomarkers; Cell Adhesion Molecules; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipid Metabolism; Lipid Metabolism Disorders; Male; Obesity; Risk Factors; Selectins; Vascular Cell Adhesion Molecule-1 | 2008 |
Choline deprivation induces hyperhomocysteinemia in rats fed low methionine diets.
Topics: Animals; Betaine; Choline; Choline Deficiency; Cysteine; Dietary Supplements; Growth; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Liver; Male; Methionine; Rats; Rats, Wistar | 2008 |
Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1alpha.
Topics: Animals; Gene Expression Regulation; Hepatocytes; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Trans-Activators; Transcription Factors; Transcription, Genetic; Transduction, Genetic | 2009 |
Homocysteine level and metabolism in ischemic stroke in the population of Northern Poland.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adolescent; Adult; Aged; Aged, 80 and over; Brain Infarction; Cystathionine beta-Synthase; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Poland; Polymorphism, Genetic; Pyridoxal Phosphate; Retrospective Studies; Risk Factors; Sequence Analysis, DNA; Vitamin B 6 | 2009 |
Homocysteine levels and risk of hip fracture in postmenopausal women.
Topics: Aged; Alcohol Drinking; Biomarkers; Case-Control Studies; Female; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Postmenopause; Risk Factors; Smoking | 2009 |
Increased prevalence of hyperhomocysteinemia in cervical artery dissection causing stroke: a case-control study.
Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Case-Control Studies; Cervical Vertebrae; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Odds Ratio; Prevalence; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Thrombosis; Vertebral Artery Dissection; Young Adult | 2009 |
Relationship of homocysteine with other risk factors and outcome of ischemic stroke.
Topics: Adult; Aged; Brain Ischemia; Comorbidity; Diabetes Mellitus; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; India; Male; Middle Aged; Obesity; Risk Factors; Severity of Illness Index; Smoking; Stroke; Tomography, X-Ray Computed; Vitamin B 12 | 2009 |
Brain MRI, apoliprotein E genotype, and plasma homocysteine in American Indian Alzheimer disease patients and Indian controls.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Brain; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Indians, North American; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Polymorphism, Genetic | 2009 |
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice.
Topics: Animals; Cystathionine beta-Synthase; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Membrane Transport Proteins; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Knockout | 2009 |
Pre-operative homocysteine levels and morbidity and mortality following cardiac surgery.
Topics: Aged; Cardiopulmonary Bypass; Epidemiologic Methods; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intraoperative Complications; Length of Stay; Male; Middle Aged; Postoperative Complications; Preoperative Care; Prognosis; Thromboembolism; Young Adult | 2009 |
Hyperhomocysteinemia, paraoxonase concentration and cardiovascular complications in Tunisian patients with nondiabetic renal disease.
Topics: Adult; Aryldialkylphosphatase; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multivariate Analysis; Radioimmunoassay; Triglycerides; Tunisia; Vitamin B 12 | 2009 |
[A survey on serum homocysteine levels and cognitive function of the middle-aged and elderly persons in Tianjin city].
Topics: Aged; Aged, 80 and over; China; Cognition; Cognition Disorders; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Sampling Studies | 2008 |
Biological plausibility between proton pump inhibitory therapy and hip fracture: hyperhomocysteinemia can be the link.
Topics: Aged; Female; Gastroesophageal Reflux; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Proton Pump Inhibitors; Risk Factors; Vitamin B 12 Deficiency | 2009 |
[The state of oxidant-antioxidant system in basal and latent hyperhomocysteinemia in patients with atherosclerosis of the lower extremity arteries].
Topics: Antioxidants; Atherosclerosis; Catalase; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Leg; Male; Malondialdehyde; Methionine; Middle Aged; Oxidative Stress; Prognosis | 2008 |
[Relationship between smoking and homocysteine concentration in ischemic stroke patients].
Topics: Aged; Brain Ischemia; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Sex Factors; Smoking; Stroke; Vitamin B 12 | 2008 |
Plasma homocysteine and gene polymorphisms associated with the risk of hyperlipidemia in northern Chinese subjects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Asian People; Base Sequence; Case-Control Studies; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors | 2008 |
[Levels of homocysteine and polymorphisms of homocysteine metabolism-related enzymes in patients with type 2 diabetes mellitus and coronary heart disease].
Topics: Adult; China; Coronary Disease; Cystathionine beta-Synthase; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2009 |
Homocysteine levels in chronic gastritis and other conditions: relations to incident cardiovascular disease and dementia.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Chronic Disease; Dementia; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Gastritis; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Risk Factors; Sweden | 2010 |
Commentary to: "Evaluation of serum lipids and carotid artery intima media thickness in epileptic children treated with valproic acid".
Topics: Age Factors; Anticonvulsants; Carotid Stenosis; Child; Endothelial Cells; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Lipid Metabolism Disorders; Risk Factors; Tunica Intima; Valproic Acid | 2009 |
Homocysteine increases the risk associated with hyperlipidaemia.
Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Europe; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Logistic Models; Male; Middle Aged; Odds Ratio; Pilot Projects; Risk Assessment; Risk Factors; Triglycerides; Up-Regulation | 2009 |
Hyperhomocysteinaemia and poor vitamin B status in chronic obstructive pulmonary disease.
Topics: Aged; C-Reactive Protein; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Forced Expiratory Volume; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Logistic Models; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Risk Factors; Thrombosis; Vital Capacity; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2009 |
Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson's disease.
Topics: Analysis of Variance; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Matched-Pair Analysis; Middle Aged; Nerve Degeneration; Parkinson Disease; Reference Values; Statistics, Nonparametric; Vitamin B 12 | 2009 |
Calpain activation is required for homocysteine-mediated hepatic degradation of inhibitor I kappa B alpha.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Calpain; Cystathionine beta-Synthase; Fatty Liver; Gene Expression; Hepatocytes; Homocysteine; Hyperhomocysteinemia; I-kappa B Proteins; Kupffer Cells; Liver; Mice; Mice, Mutant Strains; NF-KappaB Inhibitor alpha; Phosphorylation | 2009 |
Homocysteine-lowering therapy for preventing atherothrombotic events: its role in high risk population.
Topics: Atherosclerosis; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thrombosis | 2010 |
Plasma homocysteine is not associated with HIV serostatus or antiretroviral therapy in women.
Topics: Adult; Anti-HIV Agents; Cross-Sectional Studies; Female; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Middle Aged | 2009 |
Hyperhomocysteinemia, intima-media thickness and C677T MTHFR gene polymorphism: a correlation study in patients with cognitive impairment.
Topics: Aged; Aged, 80 and over; Carotid Arteries; Cognition Disorders; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Tunica Intima | 2009 |
Simvastatin suppresses homocysteine-induced apoptosis in endothelial cells: roles of caspase-3, cIAP-1 and cIAP-2.
Topics: Apoptosis; Caspase 3; Cells, Cultured; Endothelium, Vascular; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Inhibitor of Apoptosis Proteins; Simvastatin | 2009 |
High casein diet decreases plasma homocysteine concentration in rats.
Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Diet; Dose-Response Relationship, Drug; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2009 |
Hypohomocysteinemic effect of cysteine is associated with increased plasma cysteine concentration in rats fed diets low in protein and methionine levels.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Choline; Cystathionine beta-Synthase; Cysteic Acid; Cysteine; Diet, Protein-Restricted; Dietary Supplements; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Mercaptoethylamines; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; Soybean Proteins | 2009 |
Vitamin B-12 and homocysteine status among vegetarians: a global perspective.
Topics: Anemia, Pernicious; Atherosclerosis; Cardiovascular Diseases; Diet, Vegetarian; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse.
Topics: Animals; Apoptosis; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Gene Expression; Glutathione; Homocysteine; Hyperhomocysteinemia; Male; Mice; Mice, Knockout; Microarray Analysis; Mutation; Retinal Diseases; Retinal Ganglion Cells | 2009 |
Serum homocysteine in Indian adolescents.
Topics: Adolescent; Age Factors; Cardiovascular Diseases; Child; Cross-Sectional Studies; Diet; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; India; Logistic Models; Male; Mass Screening; Odds Ratio; Probability; Risk Assessment; Sex Factors; Young Adult | 2009 |
Association of plasma homocysteine concentration with cerebral white matter hyperintensity on magnetic resonance images in stroke patients.
Topics: Animals; Axons; Brain; Cerebral Arterial Diseases; Comorbidity; Diabetes Mellitus; Dyslipidemias; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipids; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Obesity; Prevalence; Risk; Smoking; Stroke; Taiwan | 2009 |
Homocysteine, lipid indices and antioxidants in patients with ischaemic heart disease from Maharashtra, India.
Topics: Adult; Antioxidants; Cholesterol; Cross-Cultural Comparison; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Myocardial Ischemia; Reference Values; Risk Factors; Rural Population; Thiobarbituric Acid Reactive Substances; Triglycerides; Young Adult | 2009 |
Beneficial effects of danshensu, an active component of Salvia miltiorrhiza, on homocysteine metabolism via the trans-sulphuration pathway in rats.
Topics: Animals; Cardiovascular Agents; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Hyperhomocysteinemia; Lactates; Male; Methionine; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza | 2009 |
[Recurrent ischemic stroke revealing Biermer's disease].
Topics: Anemia, Pernicious; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Aged; Recurrence; Vitamin B 12 | 2009 |
A case of infarction of small bowel caused by thrombophilia secondary to hyperhomocysteinaemia.
Topics: Abdomen; Homocysteine; Humans; Hyperhomocysteinemia; Infarction; Intestine, Small; Laparotomy; Male; Middle Aged; Thrombophilia; Ultrasonography | 2009 |
Homocysteine and cholesterol: guilt by association?
Topics: Atherosclerosis; Cholesterol; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia | 2009 |
Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failure.
Topics: Animals; Antioxidants; Apoptosis; Cystathionine beta-Synthase; Desmin; Disease Models, Animal; Glutathione; Glutathione Disulfide; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Kidney; Kidney Failure, Chronic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Oxidative Stress; Proteinuria; Sulfides; Superoxides | 2009 |
Plasma total homocysteine concentrations in a Turkish population sample.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Infant; Male; Middle Aged; Reference Values; Retrospective Studies; Sex Factors; Turkey; Young Adult | 2009 |
Blood levels of homocysteine, cysteine, glutathione, folic acid, and vitamin B12 in the acute phase of atherothrombotic stroke.
Topics: Acute Disease; Aged; Aged, 80 and over; Brain Ischemia; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12; Vitamins | 2009 |
Associations between plasma homocysteine levels, aortic stiffness and wave reflection in patients with arterial hypertension, isolated office hypertension and normotensive controls.
Topics: Adult; Aortic Diseases; Blood Pressure; Female; Femoral Artery; Heart Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Linear Models; Male; Middle Aged; Pulsatile Flow; Risk Factors; Smoking | 2010 |
Role of thrombotic risk factors in end-stage renal disease.
Topics: 3' Untranslated Regions; Adult; Alleles; Amino Acid Substitution; Factor V; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Point Mutation; Prothrombin; Risk Factors; Thrombophilia; Vitamin B 12; Young Adult | 2010 |
Plasma vitamins, amino acids, and renal function in postexercise hyperhomocysteinemia.
Topics: Adolescent; Amino Acids; Creatinine; Exercise; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Male; Physical Exertion; Vitamin B 12; Young Adult | 2009 |
Matrix imbalance by inducing expression of metalloproteinase and oxidative stress in cochlea of hyperhomocysteinemic mice.
Topics: Animals; Blotting, Western; Cochlea; Cystathionine beta-Synthase; Extracellular Matrix; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinases | 2009 |
Methyltetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia as a novel risk factor for diabetic nephropathy.
Topics: Adult; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Disease Susceptibility; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Single Nucleotide; Risk Factors | 2009 |
High-dose short-term folate administration modifies ambulatory blood pressure in postmenopausal women. A placebo-controlled study.
Topics: Aging; Blood Pressure; Cardiovascular Diseases; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin; Middle Aged; Postmenopause; Vitamin B Complex | 2009 |
Acute homocysteine administration impairs memory consolidation on inhibitory avoidance task and decreases hippocampal brain-derived neurotrophic factor immunocontent: prevention by folic acid treatment.
Topics: Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Folic Acid; Hippocampus; Homocysteine; Hyperhomocysteinemia; Memory; Memory Disorders; Memory, Short-Term; Motor Activity; Parietal Lobe; Random Allocation; Rats; Rats, Wistar; Time Factors; Vitamin B Complex | 2009 |
Folate/homocysteine phenotypes and MTHFR 677C>T genotypes are associated with serum levels of monocyte chemoattractant protein-1.
Topics: Adult; Chemokine CCL2; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Sex Factors; Young Adult | 2009 |
Effects of hyperhomocysteinemia on arterial pressure and nitric oxide production in pregnant rats.
Topics: Animals; Blood Pressure; Female; Homocysteine; Hyperhomocysteinemia; Nitric Oxide; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Rats | 2009 |
The factors that affect plasma homocysteine levels, pulse wave velocity and their relationship with cardiovascular disease indicators in peritoneal dialysis patients.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Pulse; Risk Factors; Young Adult | 2010 |
Induction of hepatic cyclooxygenase-2 by hyperhomocysteinemia via nuclear factor-kappaB activation.
Topics: Animals; Antioxidants; Cell Nucleus; Cyclic N-Oxides; Cyclooxygenase 2; Disease Models, Animal; Enzyme Induction; Hepatitis; Homocysteine; Hyperhomocysteinemia; I-kappa B Proteins; Liver; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Phosphorylation; Pyrrolidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spin Labels; Superoxides; Thiocarbamates; Time Factors | 2009 |
Elevated cerebrospinal fluid and plasma homocysteine levels in ALS.
Topics: Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Central Nervous System; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Predictive Value of Tests | 2010 |
Hyperhomocysteinemia induced by feeding rats diets rich in DL-homocysteine thiolactone promotes alterations on carotid reactivity independent of arterial structure.
Topics: Animals; Carotid Arteries; Feeding Methods; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar; Vasoconstriction; Vasodilation | 2009 |
A New DiaSys colorimetric assay for plasma homocysteine: application in diabetic patients.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; C-Reactive Protein; Chromatography, High Pressure Liquid; Colorimetry; Diabetes Mellitus; Female; Folic Acid; Glomerular Filtration Rate; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reproducibility of Results; Vitamin B 12 | 2009 |
MicroRNAs are involved in homocysteine-induced cardiac remodeling.
Topics: Animals; Blotting, Western; Cell Line; Gene Expression Profiling; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinases; Mice; MicroRNAs; Myocytes, Cardiac; NADPH Oxidase 4; NADPH Oxidases; Regeneration; Ribonuclease III; Tissue Inhibitor of Metalloproteinases | 2009 |
Sacroiliitis and muscle cramps in a healthy young man: some spearhead on MTHFR mutations.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Biomarkers; DNA Mutational Analysis; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Keratolytic Agents; Low Back Pain; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Cramp; Muscle, Skeletal; Mutation; Radiography; Sacroiliac Joint; Sulfasalazine; Tretinoin | 2010 |
Homocysteine and endothelial markers are increased in patients with chronic liver diseases.
Topics: Adult; Aged; Blood Coagulation Factors; Case-Control Studies; Chronic Disease; Endothelium, Vascular; Fatty Liver; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis; Male; Middle Aged; Prothrombin Time | 2009 |
[Homocysteine as health risk: who is affected?].
Topics: Cardiovascular Diseases; Child; Child, Preschool; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Reference Values; Risk Factors | 2009 |
Impaired fibrin gel permeability by high homocysteine levels.
Topics: Factor XIII; Fibrin; Fibrinogen; Fibrinolysis; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Permeability | 2011 |
Relationship between serum homocysteine and other parameters in renal transplant patients.
Topics: Azathioprine; Blood Pressure; Body Mass Index; C-Reactive Protein; Creatinine; Cross-Sectional Studies; Cyclosporine; Diabetes Mellitus; Female; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Male | 2009 |
A cross-sectional study of familial clustering in hyperhomocysteinemia.
Topics: Aged; Aging; Asian People; Cluster Analysis; Cross-Sectional Studies; Family Health; Female; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Male; Middle Aged; Prevalence; Risk Factors | 2010 |
Homocysteine level in Iranian patients with premature acute myocardial infarction.
Topics: Adult; Case-Control Studies; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Male; Middle Aged; Myocardial Infarction; Risk Factors | 2009 |
The metabolic syndrome is not associated with homocysteinemia: the Persian Gulf Healthy Heart Study.
Topics: Adult; Aged; Cardiovascular Diseases; Cross-Sectional Studies; Female; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Indian Ocean; Iran; Male; Metabolic Syndrome; Middle Aged; Prevalence; Risk Factors | 2009 |
Metabolic syndrome and homocysteine level as predictors of the severity of coronary artery disease in patients with carotid stenosis.
Topics: Adult; Aged; Aged, 80 and over; Carotid Stenosis; Coronary Angiography; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolic Syndrome; Middle Aged; Risk Factors | 2009 |
The associations between blood levels of homocysteine, folate, vitamin B12, and retinal vascular caliber.
Topics: Aged; Aging; Arterioles; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Photography; Retinal Artery; Retinal Vein; Sex Factors; Smoking; Venules; Vitamin B 12 | 2009 |
The association between high plasma homocysteine levels and lower bone mineral density in Slovak women: the impact of vegetarian diet.
Topics: Adult; Age Distribution; Aged; Albumins; Blood Glucose; Bone Density; Calcium; Causality; Cohort Studies; Creatinine; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Phosphorus; Risk Factors; Slovakia; Vitamin B 12; Young Adult | 2010 |
Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.
Topics: Animals; Annexin A2; Cell Movement; Corneal Neovascularization; Diet; Endothelial Cells; Fibrin; Fibrinolysis; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Recombinant Proteins | 2009 |
Hyperhomocysteinaemia, low folate concentrations and methylene tetrahydrofolate reductase C677T mutation in acute mesenteric venous thrombosis.
Topics: Acute Disease; Adult; Aged; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Chromatography, High Pressure Liquid; Down-Regulation; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoassay; Male; Mesenteric Vascular Occlusion; Mesenteric Veins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Risk Assessment; Risk Factors; Venous Thrombosis; Vitamin B 12; Young Adult | 2010 |
Observational study on markers of cardiovascular risk in renal patient: conventional hemodialysis vs. haemofiltration online.
Topics: Biomarkers; Cardiovascular Diseases; Chi-Square Distribution; Cross-Sectional Studies; Female; Folic Acid; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Obesity; Online Systems; Renal Dialysis; Risk Assessment; Risk Factors; Treatment Outcome; Vitamin B 12 | 2009 |
Serum folate is a reliable indicator of hyperhomocysteinemia and borderline hyperhomocysteinemia in young adults.
Topics: Adolescent; Adult; Area Under Curve; Biomarkers; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pyridoxal Phosphate; Reference Values; Risk Factors; Severity of Illness Index; Taiwan; Vitamin B 12; Young Adult | 2009 |
Hyperhomocysteinemia-induced myocardial injury after coronary artery bypass.
Topics: Aged; Biomarkers; Constriction; Coronary Artery Bypass; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Linear Models; Male; Middle Aged; Myocardial Reperfusion Injury; Myocardium; Odds Ratio; Prospective Studies; Risk Assessment; Risk Factors; Treatment Outcome; Troponin T; Up-Regulation | 2009 |
Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Brain; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Down-Regulation; Female; Food, Formulated; Glycogen Synthase Kinase 3; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Transgenic; Plaque, Amyloid; Serine | 2010 |
Effects of hyperhomocysteinemia during the gestational period on ossification in rat embryo.
Topics: Animals; Animals, Newborn; Bone Diseases, Metabolic; Female; Gestational Age; Growth Plate; Homocysteine; Hyperhomocysteinemia; Male; Microscopy; Osteogenesis; Pregnancy; Pregnancy Complications; Radius; Rats; Rats, Sprague-Dawley; Spine; Tibia | 2010 |
Hyperhomocysteinemia in patients with stasis dermatitis and ulcer: a novel finding with important therapeutic implications.
Topics: Adult; Biomarkers; Case-Control Studies; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leg Dermatoses; Male; Middle Aged; Severity of Illness Index; Treatment Outcome; Varicose Ulcer; Vitamin B Complex | 2009 |
Plasma total homocysteine levels and methylenetetrahydrofolate reductase gene polymorphism in patients with type 2 diabetes mellitus.
Topics: Adult; Brazil; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide | 2008 |
The nutrigenetics of hyperhomocysteinemia: quantitative proteomics reveals differences in the methionine cycle enzymes of gene-induced versus diet-induced hyperhomocysteinemia.
Topics: Adenosylhomocysteinase; Animals; Antioxidants; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Diet; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nutrigenomics; Peroxiredoxins; Proteomics; Urea | 2010 |
Hyperhomocysteinemia stimulates hepatic glucose output and PEPCK expression.
Topics: Animals; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; Glucose; Hepatocytes; Homocysteine; Hyperhomocysteinemia; Insulin Resistance; Isoquinolines; Mice; Mice, Inbred BALB C; Phosphoenolpyruvate Carboxykinase (ATP); Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides | 2009 |
Hepatic acyl-coenzyme a:cholesterol acyltransferase-2 expression is decreased in mice with hyperhomocysteinemia.
Topics: Acyl Coenzyme A; Animals; Cholesterol Esters; CpG Islands; Cystathionine beta-Synthase; Diet; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Lipid Metabolism; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oleic Acid; RNA, Messenger; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2 | 2010 |
Single nucleotide polymorphisms in homocysteine metabolism pathway genes: association of CHDH A119C and MTHFR C677T with hyperhomocysteinemia.
Topics: Adult; Biosynthetic Pathways; Choline Dehydrogenase; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Single Nucleotide | 2009 |
Hyperhomocysteinemia due to levodopa treatment as a risk factor for osteoporosis in patients with Parkinson's disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Bone and Bones; Bone Density; Causality; Cohort Studies; Comorbidity; Female; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Osteoporosis; Prevalence; Risk Factors; Up-Regulation | 2010 |
Chronic pancreatitis is associated with hyperhomocysteinemia and derangements in transsulfuration and transmethylation pathways.
Topics: Adult; Creatinine; Cysteine; Erythrocytes; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Middle Aged; Models, Biological; Multivariate Analysis; Pancreatitis, Alcoholic; Pancreatitis, Chronic; Regression Analysis; Signal Transduction; Sulfates; Sulfur; Young Adult | 2010 |
Hyperhomocysteinemia recurrence in levodopa-treated Parkinson's disease patients.
Topics: Aged; Cross-Sectional Studies; Dopamine Agents; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Prospective Studies; Secondary Prevention; Treatment Outcome; Vitamin B 12 | 2010 |
MTHFR C677T homozygous mutation in a patient with pigmentary glaucoma and central retinal vein occlusion.
Topics: Adult; Antihypertensive Agents; Glaucoma, Open-Angle; Gonioscopy; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Intraocular Pressure; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Single Nucleotide; Retinal Vein Occlusion | 2010 |
Effect of anemia and hyperhomocysteinemia on mortality of patients on hemodialysis.
Topics: Adolescent; Adult; Aged; Anemia; Erythropoietin; Female; Ferritins; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Renal Dialysis; Risk Factors; Transferrin; Young Adult | 2010 |
N-terminal proB-type natriuretic peptide and homocysteine concentrations in athletes.
Topics: Adult; Biomarkers; Case-Control Studies; Competitive Behavior; Female; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-6; Male; Motor Activity; Natriuretic Peptide, Brain; Peptide Fragments; Risk Factors; Sports; Statistics as Topic | 2009 |
Asymptomatic Mongolian middle-aged women with high homocysteine blood level and atherosclerotic disease.
Topics: Adult; Asian People; Atherosclerosis; Biomarkers; Cross-Sectional Studies; Diet; Female; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Logistic Models; Middle Aged; Mongolia; Odds Ratio; Prevalence; Risk Assessment; Risk Factors; Ultrasonography, Doppler; Women's Health | 2010 |
Association of hyperhomocysteinemia with left ventricular dilatation and mass in human heart.
Topics: Adult; Dilatation, Pathologic; Female; Heart Ventricles; Homocysteine; Humans; Hyperhomocysteinemia; Hypertrophy, Left Ventricular; Male; Middle Aged; Natriuretic Peptide, Brain; Ventricular Function, Left; Ventricular Remodeling | 2010 |
Cardiac specific deletion of N-methyl-d-aspartate receptor 1 ameliorates mtMMP-9 mediated autophagy/mitophagy in hyperhomocysteinemia.
Topics: Animals; Autophagy; Blotting, Western; Cell Respiration; Connexin 43; Female; Homocysteine; Hyperhomocysteinemia; Integrases; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Cardiac; Oxidative Stress; Oxygen Consumption; Peroxynitrous Acid; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics.
Topics: Aged; Aging; Analysis of Variance; California; Female; Genotype; Health Surveys; Hispanic or Latino; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B Complex; White People | 2010 |
Homocysteine induces caspase activation by endoplasmic reticulum stress in platelets from type 2 diabetics and healthy donors.
Topics: Apoptosis; Blood Donors; Blood Platelets; Calcium Signaling; Caspase 3; Caspase 9; Cells, Cultured; Cinnamates; Diabetes Mellitus, Type 2; Diabetic Angiopathies; eIF-2 Kinase; Endoplasmic Reticulum; Enzyme Activation; Homocysteine; Humans; Hyperhomocysteinemia; Stress, Physiological; Thiourea | 2010 |
Homocysteine enriched diet leads to prolonged QT interval and reduced left ventricular performance in telemetric monitored mice.
Topics: Animals; Arrhythmias, Cardiac; Cardiovascular Diseases; Connexins; Diet; Disease Models, Animal; Echocardiography; Heart Ventricles; Homocysteine; Hyperhomocysteinemia; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neural Conduction; Random Allocation; Telemetry; Ventricular Dysfunction, Left; Ventricular Remodeling | 2011 |
The effect of isotretinoin treatment on plasma homocysteine levels in acne vulgaris.
Topics: Acne Vulgaris; Adolescent; Dermatologic Agents; Female; Homocysteine; Humans; Hyperhomocysteinemia; Isotretinoin; Liver Function Tests; Male; Risk Factors; Treatment Outcome; Young Adult | 2010 |
Prevalence of hyperhomocysteinaemia in a Chinese elderly population.
Topics: Aged; Alcohol Drinking; China; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Prevalence; Sex Factors; Surveys and Questionnaires; Vitamin B 12 | 2010 |
Hyperhomocysteinemia is not associated with reduced bone quality in humans with hip osteoarthritis.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Bone Density; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osteoarthritis, Hip; Vitamin B 12; Vitamin B 6 | 2010 |
Ameliorative role of rosiglitazone in hyperhomocysteinemia-induced experimental cardiac hypertrophy.
Topics: Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Homocysteine; Hyperhomocysteinemia; Hypertrophy, Left Ventricular; Male; Methionine; Oxidative Stress; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones | 2010 |
Homocysteine: to measure or not to measure? Focus on "functional NMDA receptors in rat erythrocytes".
Topics: Animals; Calcium; Cardiovascular Diseases; Cell Shape; Cell Size; Erythrocytes; Homocysteine; Humans; Hyperhomocysteinemia; Intermediate-Conductance Calcium-Activated Potassium Channels; Kinetics; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Superoxides | 2010 |
Major determinants of serum homocysteine concentrations in a Korean population.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2010 |
Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis.
Topics: Animals; Collagen; Cystathionine beta-Synthase; Down-Regulation; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Inflammation; Kidney; Kidney Diseases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL | 2010 |
Nutrigenetic impact of daily folate intake on plasma homocysteine and folate levels in patients with different methylenetetrahydrofolate reductase genotypes.
Topics: Biomarkers; Chi-Square Distribution; Dietary Supplements; Drug Administration Schedule; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Israel; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Nutrigenomics; Odds Ratio; Phenotype | 2010 |
Increased inflammatory markers in brain and blood of rats subjected to acute homocysteine administration.
Topics: Animals; Biomarkers; Blood Proteins; Brain; C-Reactive Protein; Cerebral Cortex; Chemokines; Cytokines; Disease Models, Animal; Drug Administration Schedule; Glycoproteins; Hippocampus; Homocysteine; Hyperhomocysteinemia; Inflammation Mediators; Leukocyte Count; Orosomucoid; Rats; Rats, Wistar | 2010 |
Homocysteine and copper induce cellular apoptosis via caspase activation and nuclear translocation of apoptosis-inducing factor in neuronal cell line SH-SY5Y.
Topics: Active Transport, Cell Nucleus; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Caspases; Catalase; Cell Line, Tumor; Copper; Enzyme Activation; Homocysteine; Humans; Hyperhomocysteinemia; Neurons | 2010 |
The incidence of raised procoagulant factors and hyperhomocysteinaemia in Chinese patients with chronic venous insufficiency.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Blood Coagulation Factors; Chronic Disease; Comorbidity; Factor IX; Factor VIII; Factor XI; Female; Homocysteine; Hong Kong; Humans; Hyperhomocysteinemia; Male; Middle Aged; United Kingdom; Venous Insufficiency; Venous Thromboembolism; White People | 2010 |
Increased levels of homocysteine in patients with ulcerative colitis.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Chi-Square Distribution; Colitis, Ulcerative; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Risk Assessment; Risk Factors; Thromboembolism; Up-Regulation; Vitamin B 12; Young Adult | 2010 |
Contribution of dietary intakes of antioxidants to homocysteine-induced low density lipoprotein (LDL) oxidation in atherosclerotic patients.
Topics: Adult; Aged; Antioxidants; Atherosclerosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Risk Factors; Vitamin B 12; Vitamin B Complex | 2010 |
Effect of lipopenic and hypotensive treatment on homocysteine levels in type 2 diabetics.
Topics: Aged; Antihypertensive Agents; Biomarkers; Case-Control Studies; Chi-Square Distribution; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Male; Middle Aged; Odds Ratio; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Triglycerides; Vitamin B 12 | 2010 |
Cysteinemia, rather than homocysteinemia, is associated with plasma apolipoprotein A-I levels in hyperhomocysteinemia: lipid metabolism in cystathionine beta-synthase deficiency.
Topics: Administration, Oral; Animals; Apolipoprotein A-I; Beverages; Biomarkers; Blood Glucose; Cholesterol, HDL; Cysteine; Disease Models, Animal; Glycine; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Lipid Metabolism; Liver; Male; Mice; Mice, Knockout; RNA, Messenger; Spain; Triglycerides | 2010 |
May modifications of human plasma proteins stimulated by homocysteine and its thiolactone induce changes of hemostatic function of plasma in vitro?
Topics: Acylation; Adult; Blood Coagulation; Blood Proteins; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Sulfhydryl Compounds | 2010 |
Genetic polymorphism of methylenetetrahydrofolate reductase G1793A, hyperhomocysteinemia, and folate deficiency correlate with ulcerative colitis in central China.
Topics: Adult; Alleles; China; Colitis, Ulcerative; DNA; Female; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Prevalence; Vitamin B 12 | 2010 |
Decreased serum levels of thioredoxin in patients with coronary artery disease plus hyperhomocysteinemia is strongly associated with the disease severity.
Topics: Aged; Analysis of Variance; Biomarkers; Blood Glucose; Case-Control Studies; China; Coronary Angiography; Coronary Artery Disease; Female; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Lipids; Male; Middle Aged; Severity of Illness Index; Thioredoxin-Disulfide Reductase; Thioredoxins | 2010 |
Effect of Ocimum sanctum on homocysteine levels and lipid profile in healthy rabbits.
Topics: Administration, Oral; Animal Feed; Animals; Blood Glucose; Cardiotonic Agents; Cardiovascular Diseases; Dyslipidemias; Female; Homocysteine; Hyperhomocysteinemia; Lipid Metabolism; Lipoproteins; Male; Ocimum; Plant Leaves; Rabbits; Triglycerides | 2011 |
Relative hyperhomocysteinemia in patients with panic disorder: a case-control study.
Topics: Adolescent; Adult; Aged; Agoraphobia; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Panic Disorder; Psychiatric Status Rating Scales; Severity of Illness Index | 2010 |
Association between adherence to folic acid supplements and serum folate, and plasma homocysteine among hemodialysis patients.
Topics: Administration, Oral; Adult; Aged; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multicenter Studies as Topic; Patient Compliance; Randomized Controlled Trials as Topic; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2011 |
Association of blood lead (Pb) and plasma homocysteine: a cross sectional survey in Karachi, Pakistan.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lead; Male; Middle Aged; Pakistan; Pyridoxal Phosphate; Young Adult | 2010 |
Homocysteine induces cytoskeletal remodeling and production of reactive oxygen species in cultured cortical astrocytes.
Topics: Actin Cytoskeleton; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Cytoskeleton; Homocysteine; Hyperhomocysteinemia; Oxidative Stress; Phosphorylation; Rats; Rats, Wistar; Reactive Oxygen Species | 2010 |
Polymorphism of MTHFR C677T, serum vitamin levels and cognition in subjects with hyperhomocysteinemia in China.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
Could genetic analysis be useful in reducing cerebrovascular risk in hypertensive subjects with hyperhomocysteinemia and patent foramen ovale? A 2-year follow-up study.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Blood Pressure; Cerebrovascular Disorders; Chi-Square Distribution; Echocardiography, Transesophageal; Female; Folic Acid; Follow-Up Studies; Foramen Ovale, Patent; Gene Frequency; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Hypertension; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymorphism, Genetic; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial; Vitamins; Young Adult | 2010 |
Homocysteine impaired endothelial function through compromised vascular endothelial growth factor/Akt/endothelial nitric oxide synthase signalling.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Cell Culture Techniques; Cell Line; Disease Models, Animal; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Nitric Oxide; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vasodilation | 2010 |
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Hyperhomocysteinemia is associated with decreased erythropoietin expression in rats.
Topics: Adenosylhomocysteinase; Animals; Carbon Monoxide; Erythropoietin; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Sprague-Dawley | 2010 |
Vitamin B12 and folic acid supplementation and plasma total homocysteine concentrations in pregnant Indian women with low B12 and high folate status.
Topics: Adult; Dietary Supplements; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Rural Population; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Hyperhomocysteinemia and cardiovascular risks in hemodialysis patients.
Topics: Adult; Aortic Valve Insufficiency; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Echocardiography, Doppler; Echocardiography, Doppler, Color; Female; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Contraction; Renal Dialysis; Risk Assessment; Risk Factors; Stroke Volume; Up-Regulation; Ventricular Function, Left | 2010 |
Hyperhomocysteinemia in Alzheimer dementia patients and cognitive decline after 6 months follow-up period.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cognition Disorders; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Retrospective Studies | 2010 |
Effect of nephrotic syndrome on homocysteine metabolism.
Topics: Animals; Blotting, Western; Cystathionine beta-Synthase; Homocysteine; Hypercholesterolemia; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Nephrotic Syndrome; Proteinuria; Rats; Rats, Sprague-Dawley | 2011 |
Frequency of afterload homocysteinemia in normal population of Southern Iran: a pilot study.
Topics: Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Male; Methionine; Pilot Projects; Young Adult | 2010 |
Attenuation of beta2-adrenergic receptors and homocysteine metabolic enzymes cause diabetic cardiomyopathy.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Cardiomyopathies; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Folic Acid; Glucose; Glucose Transporter Type 4; Heart Failure; Homocysteine; Hyperglycemia; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardial Contraction; Myocytes, Cardiac; Receptors, Adrenergic, beta-2; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2010 |
Homocysteine impairs coronary artery endothelial function by inhibiting tetrahydrobiopterin in patients with hyperhomocysteinemia.
Topics: Adult; Aged; Biopterins; Blood Flow Velocity; Chromatography, High Pressure Liquid; Coronary Vessels; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Statistics, Nonparametric | 2010 |
Effect of resveratrol on hemostatic properties of human fibrinogen and plasma during model of hyperhomocysteinemia.
Topics: Adult; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Resveratrol; Stilbenes | 2010 |
[The role of homocysteine levels in the pathogenesis of cognitive disorders in patients with chronic cerebral ischemia].
Topics: Aged; Brain Ischemia; Cognition Disorders; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Severity of Illness Index | 2009 |
Homocysteine levels in patients with heart failure with preserved ejection fraction.
Topics: Aged; Female; Heart Failure, Diastolic; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Prospective Studies; Pulmonary Edema; Risk Factors; Stroke Volume; Ventricular Function, Left | 2010 |
Homocysteine, another risk factor for Alzheimer disease, impairs apolipoprotein E3 function.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apolipoprotein E3; Apolipoprotein E4; Brain; Disulfides; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Mice; Mice, Knockout; Protein Multimerization; Risk Factors | 2010 |
The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis.
Topics: Activated Protein C Resistance; Aged; Blood Coagulation Tests; Cohort Studies; Comorbidity; Factor V; Female; Folic Acid; Homocysteine; Homocystinuria; Hospital Mortality; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Point Mutation; Protein C; Psychotic Disorders; Respiration, Artificial; Sepsis; Shock, Septic; Thrombophilia; Vitamin B 12 | 2010 |
Myocardial fibrosis and TGFB expression in hyperhomocysteinemic rats.
Topics: Animals; Collagen; Enzyme Activation; Extracellular Matrix; Fibrosis; Homocysteine; Hyperhomocysteinemia; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Myocardium; Myocytes, Cardiac; Rats; Rats, Wistar; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2011 |
Homocysteine and chronic pancreatitis.
Topics: Adolescent; Adult; Aged; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Pancreatitis, Alcoholic; Pancreatitis, Chronic; Young Adult | 2010 |
Methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish patients with polycystic ovary syndrome.
Topics: Adult; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polycystic Ovary Syndrome; Polymorphism, Genetic; Turkey; Young Adult | 2010 |
Prevention: B vitamins and CVD--failure to find a simple solution.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B Complex | 2010 |
[The relationship of methylenetetrahydrofolate reductase G1793A gene polymorphism, hyperhomocysteinaemia and ulcerative colitis].
Topics: Adult; Case-Control Studies; Colitis, Ulcerative; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12 | 2010 |
Homocysteine, folic acid and vitamin B12 levels in maternal and umbilical cord plasma and homocysteine levels in placenta in pregnant women with pre-eclampsia.
Topics: Adult; Case-Control Studies; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Placenta; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Vitamin B 12 | 2011 |
Hyperhomocysteinemia and the methylene tetrahydrofolate reductase C677T mutation in splanchnic vein thrombosis.
Topics: Adult; Cholesterol; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Mutation; Spain; Splanchnic Circulation; Venous Thrombosis | 2011 |
Mesenteric vascular remodeling in hyperhomocysteinemia.
Topics: Abdominal Pain; Amidohydrolases; Animals; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blotting, Western; Connexins; Cystathionine beta-Synthase; Disease Models, Animal; Elasticity; Elastin; Extracellular Matrix Proteins; Fluorescent Antibody Technique; Gap Junction alpha-5 Protein; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Matrix Metalloproteinase 9; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Microscopy, Video; Nitric Oxide Synthase Type III; Nitrites; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Splanchnic Circulation; Telemetry; Vascular Resistance | 2011 |
Homocysteine induces oxidative-nitrative stress in heart of rats: prevention by folic acid.
Topics: Animals; Antioxidants; Catalase; Disease Models, Animal; Female; Fluoresceins; Folic Acid; Heart Diseases; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Male; Myocardium; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Reactive Nitrogen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2011 |
Mutations in methylenetetrahydrofolate reductase and in cysthationine beta synthase: is there a link to homocysteine levels in peripheral arterial disease?
Topics: Aged; Brazil; Cystathionine beta-Synthase; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Peripheral Arterial Disease; Risk Factors | 2011 |
The thermolabile variant of 5,10-methylenetetrahydrofolate reductase is a possible risk factor for amyotrophic lateral sclerosis.
Topics: Adolescent; Adult; Aged; Amyotrophic Lateral Sclerosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Isoenzymes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nerve Degeneration; Risk Factors; Temperature; Young Adult | 2011 |
Integrin α(IIb)β₃ exists in an activated state in subjects with elevated plasma homocysteine levels.
Topics: Antibodies; Binding Sites, Antibody; Blood Platelets; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Integrins; Male; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Risk Factors; Sulfhydryl Compounds; Thrombosis | 2011 |
[The effect of recombined BHMT on the Hhcy rat].
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar; Recombinant Proteins | 2004 |
Branch retinal artery occlusion and non-ischemic central retinal vein occlusion due to hyperhomocysteinemia in a 14-year-old child.
Topics: Adolescent; Blindness; Female; Fluorescein Angiography; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Retinal Artery Occlusion; Retinal Vein Occlusion; Retinal Vessels; Tomography, Optical Coherence; Visual Acuity; Visual Field Tests; Visual Fields | 2010 |
Hyperhomocysteinemia does not affect global DNA methylation and nicotinamide N-methyltransferase expression in mice.
Topics: Animals; Brain; Disease Models, Animal; DNA Methylation; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Leukocytes; Mice; Mice, Inbred ICR; Nicotinamide N-Methyltransferase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2011 |
Regulation of hepatic cholesterol biosynthesis by berberine during hyperhomocysteinemia.
Topics: Alanine Transaminase; AMP-Activated Protein Kinases; Animals; Aspartate Aminotransferases; Berberine; Cholesterol; Disease Models, Animal; Enzyme Activation; Hep G2 Cells; Homocysteine; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Liver; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, LDL; Time Factors; Up-Regulation | 2011 |
Atherosclerotic and thrombophilic risk factors in patients with ischemic central retinal vein occlusion.
Topics: Acute Disease; Aged; Atherosclerosis; Biomarkers; Dyslipidemias; Factor VIII; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Ischemia; Male; Retinal Vein Occlusion; Risk Factors; Thrombophilia | 2011 |
Comparison of the effect of homocysteine in the reduced form, its thiolactone and protein homocysteinylation on hemostatic properties of plasma.
Topics: Adult; Blood Coagulation; Blood Proteins; Fibrinogen; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Oxidation-Reduction; Sulfhydryl Compounds | 2011 |
A derangement of the maternal lipid profile is associated with an elevated risk of congenital heart disease in the offspring.
Topics: Adult; Apolipoproteins B; Body Mass Index; Case-Control Studies; Child; Cholesterol, LDL; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Hyperglycemia; Hyperhomocysteinemia; Logistic Models; Multivariate Analysis; Odds Ratio; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Young Adult | 2012 |
Foreword to special issue on homocysteine disorders.
Topics: Congresses as Topic; Dietary Supplements; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Diseases; Metabolic Networks and Pathways; Metabolism, Inborn Errors; Vitamin B 12 | 2011 |
Homocysteine alters glutamate uptake and Na+,K+-ATPase activity and oxidative status in rats hippocampus: protection by vitamin C.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Glutamic Acid; Hippocampus; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2011 |
Phytoestrogen α-zearalanol improves vascular function in ovariectomized hyperhomocysteinemic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelin-1; Estradiol; Female; Homocysteine; Hyperhomocysteinemia; Methionine; Nitric Oxide Synthase Type III; Nitroprusside; Ovariectomy; Phenylephrine; Phytoestrogens; Rats; Rats, Wistar; Zeranol | 2011 |
Plasma homocysteine and the severity of heart failure in patients with previous myocardial infarction.
Topics: Aged; Biomarkers; Chi-Square Distribution; Chronic Disease; Cross-Sectional Studies; Echocardiography, Doppler; Female; Fluorescence Polarization Immunoassay; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Predictive Value of Tests; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke Volume; Up-Regulation; Ventricular Function, Left | 2011 |
Inborn errors of cobalamin absorption and metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Anemia, Megaloblastic; Cobamides; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Malabsorption Syndromes; Metabolism, Inborn Errors; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Neonatal Screening; Proteinuria; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Association of haptoglobin genotype and common cardiovascular risk factors with the amount of iron in atherosclerotic carotid plaques.
Topics: Aged; Cardiovascular Diseases; Carotid Stenosis; Diabetes Mellitus; Endarterectomy, Carotid; Female; Genetic Predisposition to Disease; Greece; Haptoglobins; Hemosiderin; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Iron; Linear Models; Male; Middle Aged; Oxidative Stress; Phenotype; Plaque, Atherosclerotic; Risk Assessment; Risk Factors; Severity of Illness Index; Sex Factors; Staining and Labeling | 2011 |
Homocysteinylated fibrinogen forms disulfide-linked complexes with albumin.
Topics: Albumins; Animals; Blotting, Western; Disulfides; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Rabbits | 2011 |
Hyperhomocysteinemia, obesity and cryptogenic stroke.
Topics: Adult; Case-Control Studies; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Obesity; Risk Factors; Stroke | 2011 |
Homocysteine levels and the metabolic syndrome in a Mediterranean population: a case-control study.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolic Syndrome; Middle Aged | 2011 |
Hyperhomocysteinemia decreases bone blood flow.
Topics: Animals; Biomarkers; Biomechanical Phenomena; Blood Pressure; Bone Density; Bone Remodeling; Disease Models, Animal; Folic Acid; Homocysteine; Hyperhomocysteinemia; Laser-Doppler Flowmetry; Male; Osteoporosis; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tibia; Time Factors; Up-Regulation; Vitamin B 12 | 2011 |
Folate and vitamin B12 improved alcohol-induced hyperhomocysteinemia in rats.
Topics: Animals; Cytochromes; Folic Acid; Homocysteine; Hyperhomocysteinemia; Liver; Liver Cirrhosis, Alcoholic; Liver Function Tests; Male; Matrix Metalloproteinase 2; Rats; Rats, Wistar; Vitamin B 12; Vitamin B Complex | 2011 |
Hyperhomocysteinaemia, vascular related pregnancy complications and the response to vitamin supplementation in pregnant women of Pakistan.
Topics: Abruptio Placentae; Case-Control Studies; Cohort Studies; Eclampsia; Female; Folic Acid; Gestational Age; Homocysteine; Hospitals, Teaching; Humans; Hyperhomocysteinemia; Pakistan; Pregnancy; Pregnancy Outcome; Vitamin B 6; Vitamin B Complex | 2010 |
Homocysteine and cerebral small vessel disease in patients with symptomatic atherosclerotic disease. The SMART-MR study.
Topics: Aged; Atherosclerosis; Brain; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Risk Factors | 2011 |
Inhibition of hepatic glycogen synthesis by hyperhomocysteinemia mediated by TRB3.
Topics: Animals; Cell Cycle Proteins; Disease Progression; Glycogen; Homocysteine; Humans; Hyperhomocysteinemia; Indoles; Insulin Resistance; Liver Glycogen; Methionine; Mice; Phosphorylation; PPAR gamma; Protein Serine-Threonine Kinases; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering | 2011 |
What is the meaning of homocysteine in patients on dialysis?
Topics: Adult; Aged; Biomarkers; Brazil; C-Reactive Protein; Creatine Kinase; Creatinine; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-6; Kidney Failure, Chronic; Linear Models; Lipids; Male; Malnutrition; Middle Aged; Peritoneal Dialysis; Prevalence; Renal Dialysis; Risk Factors; Tumor Necrosis Factor-alpha; Vitamin B 12 | 2011 |
Homocysteine mediated decrease in bone blood flow and remodeling: role of folic acid.
Topics: Animals; Bone Density; Bone Remodeling; Folic Acid; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Mice; Nitric Oxide; Osteoporosis; Oxidative Stress; Regional Blood Flow; Tibia; Tibial Arteries | 2011 |
Vitamin B12 deficiency, hyperhomocysteinemia and thrombosis: a case and control study.
Topics: Adult; Aged; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Methionine-induced homocysteinemia impairs endothelial function in hypertensives: the role of asymmetrical dimethylarginine and antioxidant vitamins.
Topics: Adult; Antioxidants; Arginine; Ascorbic Acid; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methionine; Middle Aged; Vasodilation; Vitamin E | 2011 |
High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dietary Fats; Down-Regulation; Fatty Liver; Homocysteine; Hyperhomocysteinemia; Insulin; Liver; Male; Metabolic Networks and Pathways; Methyltransferases; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Transcription, Genetic; Triglycerides | 2011 |
Vitamin B12 and folate deficiency and elevated plasma total homocysteine in workers with chronic exposure to chromate.
Topics: Adult; China; Chromates; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
Folate is related to phosphorylated neurofilament-H and P-tau (Ser396) in rat brain.
Topics: Animals; Brain; Female; Folic Acid; Frontal Lobe; Homocysteine; Homocystine; Hyperhomocysteinemia; Methionine; Methylation; Neurofilament Proteins; Phosphoproteins; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; tau Proteins | 2011 |
Response of blood platelets to resveratrol during a model of hyperhomocysteinemia.
Topics: Adult; Antioxidants; Blood Platelets; Homocysteine; Humans; Hyperhomocysteinemia; Platelet Aggregation; Resveratrol; Stilbenes; Superoxides; Young Adult | 2011 |
Hyperhomocysteinemia inhibited cardiac stem cell homing into the peri-infarcted area post myocardial infarction in rats.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Movement; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Male; Methionine; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Factor; Stem Cells | 2011 |
The basis of differential responses to folic acid supplementation.
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Genetic; Nutrigenomics; Polymorphism, Single Nucleotide; Twins, Dizygotic; Twins, Monozygotic; Vitamin B 12 | 2011 |
Homocysteine-mediated modulation of mitochondrial dynamics in retinal ganglion cells.
Topics: Animals; Animals, Newborn; Axons; Caspase 3; Cells, Cultured; Disease Models, Animal; DNA Primers; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique, Indirect; GTP Phosphohydrolases; Homocysteine; Hyperhomocysteinemia; Immunoenzyme Techniques; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Cognitive and neurochemical alterations in hyperhomocysteinemic rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain-Derived Neurotrophic Factor; Cognition; Dopamine; Hippocampus; Homocysteine; Homovanillic Acid; Hydroxyindoleacetic Acid; Hyperhomocysteinemia; Male; Maze Learning; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin | 2012 |
Hyperhomocysteinemia impairs endothelium-derived hyperpolarizing factor-mediated vasorelaxation in transgenic cystathionine beta synthase-deficient mice.
Topics: Animals; Biological Factors; Cardiovascular Diseases; Cell Line; Cystathionine beta-Synthase; Gene Deletion; Homocysteine; Humans; Hyperhomocysteinemia; Mesenteric Arteries; Mice; Mice, Transgenic; Nitrogen Oxides; Vasodilation | 2011 |
Homocysteine, B vitamins, and the risk of cardiovascular disease.
Topics: Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Peripheral Vascular Diseases; Risk; Vitamin B Complex | 2011 |
Genotype-independent in vivo oxidative stress following a methionine loading test: maximal platelet activation in subjects with early-onset thrombosis.
Topics: Adult; Age of Onset; Analysis of Variance; Biomarkers; Case-Control Studies; Chi-Square Distribution; Cystathionine beta-Synthase; Dinoprost; Female; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Italy; Linear Models; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidative Stress; Phenotype; Platelet Activation; Platelet Function Tests; Thrombosis; Thromboxane B2; Time Factors | 2011 |
TT genotype of the methylenetetrahydrofolate reductase C677T polymorphism is an important determinant for homocysteine levels in multi-ethnic Malaysian ischaemic stroke patients.
Topics: China; Ethnicity; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Malaysia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Genetic; Stroke; Vitamin B 12 | 2011 |
Nitrous oxide anesthesia and plasma homocysteine in adolescents.
Topics: Adolescent; Age Factors; Anesthetics, Inhalation; Child; Elective Surgical Procedures; Female; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Missouri; Nitrous Oxide; Orthopedic Procedures; Spine; Time Factors; Up-Regulation | 2011 |
Development of an animal model for chronic mild hyperhomocysteinemia and its response to oxidative damage.
Topics: Animals; Antioxidants; Catalase; Cerebral Cortex; Disease Models, Animal; Glutathione Peroxidase; Homocysteine; Humans; Hyperhomocysteinemia; Nitrites; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2011 |
Chronic hyperhomocysteinemia induces oxidative damage in the rat lung.
Topics: Animals; Catalase; Chronic Disease; Fluoresceins; Fluorescence; Glutathione; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Lung; Models, Biological; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2011 |
Bilateral crystalline lens dislocation associated with dilated cardiomyopathy in a patient with underlying hyperhomocysteinaemia.
Topics: Biomarkers; Cardiomyopathy, Dilated; Diagnosis, Differential; Echocardiography; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lens Subluxation; Middle Aged; Ophthalmoscopy | 2012 |
Reduction of superior mesenteric hemodynamic responsiveness to [Sar1, Thr8]-angiotensin II and bradykinin, but not sodium nitroprusside, in the presence of homocysteine infusion.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Endothelium, Vascular; Hemodynamics; Homocysteine; Hyperhomocysteinemia; Infusions, Intravenous; Male; Mesenteric Artery, Superior; Models, Animal; Nitroprusside; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vascular Resistance | 2010 |
Relation of homocysteinemia to contrast-induced nephropathy in patients undergoing percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Female; Follow-Up Studies; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Prognosis; Retrospective Studies; Time Factors; Triiodobenzoic Acids | 2011 |
Homocysteine metabolism in polycystic ovary syndrome.
Topics: Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperandrogenism; Hyperhomocysteinemia; Insulin Resistance; Polycystic Ovary Syndrome; Risk Factors | 2012 |
Relationship between lipid profiles and plasma total homocysteine, cysteine and the risk of coronary artery disease in coronary angiographic subjects.
Topics: Adult; Aged; Aged, 80 and over; Apolipoprotein A-I; Cholesterol, HDL; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Middle Aged; Prevalence; Risk Factors; Statistics, Nonparametric | 2011 |
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cysteine; Diet; Enzyme Inhibitors; Fatty Liver; Glutathione; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 2011 |
Evaluation of the MTHFR A1298C variant in leukoaraiosis.
Topics: Adult; Aged; Female; Genetic Carrier Screening; Genetic Predisposition to Disease; Genetic Variation; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multigene Family; Point Mutation; Risk Factors | 2012 |
Intravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors.
Topics: Animals; Calbindins; Diabetic Retinopathy; Dose-Response Relationship, Drug; Eye Proteins; Female; Glial Fibrillary Acidic Protein; Homeodomain Proteins; Homocysteine; Hyperhomocysteinemia; Immunoblotting; Immunohistochemistry; Intravitreal Injections; LIM-Homeodomain Proteins; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Paired Box Transcription Factors; PAX6 Transcription Factor; Photoreceptor Cells; Repressor Proteins; Retina; Retinal Degeneration; Retinal Ganglion Cells; Rhodopsin; S100 Calcium Binding Protein G; Transcription Factors | 2011 |
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil.
Topics: Brazil; Cross-Sectional Studies; Female; Genotype; Hepatitis C, Chronic; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2011 |
The effects of hyperhomocysteinemia on the microcirculation of skin flaps.
Topics: Animals; Disease Models, Animal; Graft Survival; Homocysteine; Hyperhomocysteinemia; Male; Microcirculation; Microvessels; Necrosis; Rats; Rats, Sprague-Dawley; Surgical Flaps | 2011 |
Association of MTHFR and RFC1 gene polymorphism with hyperhomocysteinemia and its modulation by vitamin B12 and folic acid in an Indian population.
Topics: Adult; Alleles; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Polymorphism, Single Nucleotide; Prevalence; Replication Protein C; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Reference interval and determinants of the serum homocysteine level in a Korean population.
Topics: Adult; Aged; Analysis of Variance; Asian People; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Life Style; Male; Middle Aged; Nutritional Status; Reference Values; Republic of Korea; Statistics, Nonparametric | 2011 |
Diagnostic efficacy of total homocysteine and C-reactive protein for ocular ischemic syndrome.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Carotid Stenosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Male; Middle Aged; Retinal Vein Occlusion; Sensitivity and Specificity | 2011 |
Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration.
Topics: Animals; Biomarkers; Brain; Folic Acid Deficiency; Formates; Homocysteine; Hyperhomocysteinemia; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methionine; Methylation; Methylmalonic Acid; Models, Biological; Random Allocation; Rats; Rats, Sprague-Dawley; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2012 |
Hyperhomocysteinemia is independently associated with albuminuria in the population-based CoLaus study.
Topics: Adult; Aged; Albuminuria; Causality; Cross-Sectional Studies; Female; Genotype; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Risk; Surveys and Questionnaires; Switzerland; Uric Acid | 2011 |
Hyperhomocysteinemia and related genetic polymorphisms correlate with ulcerative colitis in Chinese Han population in Central China [corrected].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Alleles; Amino Acid Substitution; Asian People; China; Colitis, Ulcerative; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2012 |
Serum homocysteine and folate but not vitamin B12 are predictors of CHD mortality in older adults.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Coronary Disease; Down-Regulation; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; New South Wales; Prognosis; Proportional Hazards Models; Risk Assessment; Risk Factors; Up-Regulation; Vitamin B 12 | 2012 |
[Serum levels of antioxidants and vitamins related to the homocystein's metabolism during postmenopause].
Topics: Abdominal Fat; Antioxidants; Body Mass Index; Cross-Sectional Studies; Estrogens; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Middle Aged; Motor Activity; Overweight; Postmenopause; Progesterone; Risk; Urban Population; Vitamin B 12; Vitamin B 6; Waist-Hip Ratio | 2005 |
[Hyperhomocysteinemia and schizophrenia: case control study].
Topics: Adult; Case-Control Studies; Chronic Disease; Comorbidity; Cross-Sectional Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reference Values; Schizophrenia; Schizophrenic Psychology; Statistics as Topic; Vitamin B 12 | 2011 |
Erythrocyte glutathione transferase: a potential new biomarker in chronic kidney diseases which correlates with plasma homocysteine.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Erythrocytes; Female; Glutathione Transferase; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Young Adult | 2012 |
Homocysteine and its thiolactone-mediated modification of fibrinogen affect blood platelet adhesion.
Topics: Adult; Blood Platelets; Fibrinogen; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Platelet Adhesiveness; Young Adult | 2012 |
Chronic mild hyperhomocysteinemia alters ectonucleotidase activities and gene expression of ecto-5'-nucleotidase/CD73 in rat lymphocytes.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Homocysteine; Hyperhomocysteinemia; Lymphocytes; Mesentery; Rats; Rats, Wistar | 2012 |
Status of B-vitamins and homocysteine in diabetic retinopathy: association with vitamin-B12 deficiency and hyperhomocysteinemia.
Topics: Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Diabetic Retinopathy; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Risk Factors; Vitamin B 12 Deficiency; Vitamin B Complex | 2011 |
Cognitive dysfunction and depression in adult kidney transplant recipients: baseline findings from the FAVORIT Ancillary Cognitive Trial (FACT).
Topics: Cognition Disorders; Cross-Sectional Studies; Depression; Dietary Supplements; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Kidney Transplantation; Logistic Models; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Vitamin B Deficiency; Vitamins | 2012 |
Fortification of flours with folic acid reduces homocysteine levels in Brazilian women.
Topics: Adult; Biomarkers; Brazil; Cardiovascular Diseases; Cross-Sectional Studies; Diet; Dietary Fiber; Edible Grain; Female; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Nutrition Assessment; Nutrition Policy; Obesity; Triticum; Zea mays | 2011 |
Serum holotranscobalamine, vitamin B12, folic acid and homocysteine levels in patients with vitiligo.
Topics: Adult; Biomarkers; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Logistic Models; Male; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitiligo; Young Adult | 2012 |
Nitrative stress in cerebral endothelium is mediated by mGluR5 in hyperhomocysteinemia.
Topics: Amidines; Animals; Benzylamines; Brain; Endothelium; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression Regulation, Enzymologic; Glycine; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Phenylacetates; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Stress, Physiological; Tyrosine | 2012 |
Hyperhomocysteinemia among Omani autistic children: a case-control study.
Topics: Autistic Disorder; Biomarkers; Case-Control Studies; Child, Preschool; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Reference Values; Vitamin B 12 | 2011 |
Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia.
Topics: Aging; Animals; Cystathionine beta-Synthase; Dark Adaptation; Disease Models, Animal; Electroretinography; Evoked Potentials, Visual; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Retina; Retinal Pigment Epithelium; Visual Acuity; Visual Cortex | 2012 |
Effect of N-homocysteinylation on physicochemical and cytotoxic properties of amyloid β-peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Chemical Phenomena; Cytotoxins; Homocysteine; Humans; Hyperhomocysteinemia; PC12 Cells; Protein Multimerization; Protein Processing, Post-Translational; Rats; Structure-Activity Relationship | 2012 |
A natural squamosamide derivative FLZ inhibits homocysteine-induced rat brain microvascular endothelial cells dysfunction.
Topics: Animals; Apoptosis; Benzeneacetamides; Brain; Cell Survival; Cells, Cultured; Cellular Senescence; Cytochromes c; Cytoprotection; Endothelium, Vascular; fas Receptor; Homocysteine; Hyperhomocysteinemia; Microvessels; NF-kappa B; Phenols; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Staining and Labeling; Tumor Suppressor Protein p53 | 2012 |
Involvement of endoplasmic reticulum stress in homocysteine-induced apoptosis of osteoblastic cells.
Topics: Apoptosis; Caspase 3; Caspase Inhibitors; Cell Line; Cell Survival; Cells, Cultured; Endoplasmic Reticulum Stress; Endoribonucleases; Gene Silencing; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Molecular Targeted Therapy; Organ Specificity; Osteoarthritis, Knee; Osteoblasts; Osteoporosis; Protein Serine-Threonine Kinases; RNA, Small Interfering; Synovial Membrane | 2012 |
Therapy of hyperhomocysteinemia in hemodialysis patients: effects of folates and N-acetylcysteine.
Topics: Acetylcysteine; Aged; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 2012 |
Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress.
Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Male; MAP Kinase Signaling System; Mice; Myocardial Contraction; Myocytes, Cardiac; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Reactive Oxygen Species; Thioredoxins | 2012 |
Metabolism and neurotoxicity of homocysteine thiolactone in mice: protective role of bleomycin hydrolase.
Topics: Animals; Blood Proteins; Brain; Cysteine Endopeptidases; Female; Half-Life; Homocysteine; Hyperhomocysteinemia; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurodegenerative Diseases; Organ Specificity; Seizures | 2012 |
Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARα, interferon-γ, and interleukin-10.
Topics: Animals; Apolipoprotein A-I; Choline Deficiency; DNA Methylation; Female; Gene Expression; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Inflammation Mediators; Interferon-gamma; Interleukin-10; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Knockout; Muscle Spasticity; Placenta; PPAR alpha; Pregnancy; Pregnancy Complications; Promoter Regions, Genetic; Psychotic Disorders; RNA, Messenger | 2012 |
Aronia melanocarpa extract suppresses the biotoxicity of homocysteine and its metabolite on the hemostatic activity of fibrinogen and plasma.
Topics: Adult; Anticoagulants; Antioxidants; Blood Coagulation; Cardiovascular Diseases; Coagulants; Dietary Supplements; Fibrinogen; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Oxidative Stress; Photinia; Plant Extracts; Poland; Polymerization; Resveratrol; Stilbenes | 2012 |
Estrogen replacement attenuates exaggerated neointimal hyperplasia following carotid endarterectomy in rats.
Topics: Angioplasty; Animals; Biomarkers; Carotid Artery Injuries; Carotid Artery, Common; Carotid Stenosis; Disease Models, Animal; Endarterectomy, Carotid; Estradiol; Estrogen Replacement Therapy; Female; Homocysteine; Hyperhomocysteinemia; Hyperplasia; Infusion Pumps, Implantable; Jugular Veins; Ovariectomy; Rats; Rats, Sprague-Dawley; Time Factors; Tunica Intima | 2011 |
Folate depletion changes gene expression of fatty acid metabolism, DNA synthesis, and circadian cycle in male mice.
Topics: Animals; Circadian Rhythm; Darkness; DNA; DNA Methylation; DNA Replication; Fatty Acids; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Hyperhomocysteinemia; Light; Lipid Metabolism; Liver; Male; Melatonin; Mice; Nuclear Proteins; Phosphatidate Phosphatase; Vitamin B Complex | 2012 |
Coenzyme Q10, hyperhomocysteinemia and MTHFR C677T polymorphism in levodopa-treated Parkinson's disease patients.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; Ubiquinone; Vitamin B 12 | 2012 |
Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo.
Topics: 8,11,14-Eicosatrienoic Acid; Activating Transcription Factor 6; Animals; Aorta; Base Sequence; DNA Methylation; Endothelial Cells; Epoxide Hydrolases; Gene Expression Regulation, Enzymologic; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Promoter Regions, Genetic; Pyrenes; RNA, Small Interfering; Solubility; Up-Regulation | 2012 |
Total homocysteine levels and cardiovascular risk factors in healthy Tunisians.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Factors; Tunisia | 2011 |
Pregnancy and a rare MTHFR haplotype.
Topics: Adult; Female; Folic Acid; Haplotypes; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications | 2012 |
Higher incidence of C677T polymorphism of the MTHFR gene in North Indian patients with vascular disease.
Topics: Adolescent; Adult; Aged; Biomarkers; Case-Control Studies; Chi-Square Distribution; Female; Gene Frequency; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoassay; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Assessment; Risk Factors; Urban Population; Vascular Diseases; Young Adult | 2012 |
Homocysteine Slovakia study: study design and occurrence of hyperhomocysteinaemia and other risk factors.
Topics: Adult; Aged; Female; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Middle Aged; Myocardial Ischemia; Risk Factors; Slovakia; Vitamins | 2012 |
Metabolism and neurotoxicity of homocysteine thiolactone in mice: evidence for a protective role of paraoxonase 1.
Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Brain; Epilepsy; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kidney; Liver; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Degeneration; Spleen | 2012 |
Marked gender difference in plasma total homocysteine concentrations in indian adults with low vitamin B₁₂.
Topics: Adult; Age Factors; Body Composition; Erythrocytes; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Role of folic acid depletion on homocysteine serum level in children and adolescents with epilepsy and different MTHFR C677T genotypes.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vitamin B 12 | 2012 |
Genetic and environmental influences on total plasma homocysteine and its role in coronary artery disease risk.
Topics: Adult; Aged; Constriction, Pathologic; Coronary Artery Disease; Diuretics; Female; Gene-Environment Interaction; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lebanon; Liver-Specific Organic Anion Transporter 1; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Organic Anion Transporters; Polymorphism, Genetic; Risk Factors | 2012 |
Nɛ-homocysteinyl-lysine isopeptide is associated with progression of peripheral artery disease in patients treated with folic acid.
Topics: Aged; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolism; Middle Aged; Oxidative Stress; Peptides; Peripheral Arterial Disease; Proteins; Vitamin B Complex | 2012 |
Content of total homocysteine and major aminothiols in rats with experimental renal ischemia.
Topics: Animals; Blood Pressure; Cysteine; Glutathione; Homocysteine; Hyperhomocysteinemia; Ischemia; Kidney; Male; Rats; Rats, Wistar; Renal Artery; Renal Artery Obstruction | 2011 |
Homocysteine levels in morbidly obese patients: its association with waist circumference and insulin resistance.
Topics: Adult; Blood Glucose; Female; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Leptin; Male; Metabolic Syndrome; Middle Aged; Obesity, Abdominal; Obesity, Morbid; Waist Circumference | 2012 |
Polymorphisms in MTHFR, MS and CBS genes and homocysteine levels in a Pakistani population.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Pakistan; Polymorphism, Single Nucleotide; Pyridoxal Phosphate; Risk Factors; Sex Factors; Vitamin B 12; Young Adult | 2012 |
Epigenetic regulation of glucocorticoid receptor expression in aorta from mice with hyperhomocysteinemia.
Topics: Animals; Aorta; Binding Sites; Chromatin Immunoprecipitation; Cystathionine beta-Synthase; Diet; DNA Methylation; Epigenesis, Genetic; Heterozygote; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Nuclear Respiratory Factor 1; Promoter Regions, Genetic; Receptors, Glucocorticoid; RNA, Messenger; Sequence Analysis, DNA | 2012 |
Serum folate, total homocysteine levels and methylenetetrahydrofolate reductase 677C>T polymorphism in young healthy female Japanese.
Topics: Adolescent; Amplified Fragment Length Polymorphism Analysis; Child; Diet; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Health Surveys; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2012 |
Reduced plasma levels of asymmetric di-methylarginine (ADMA) in patients with alcohol dependence normalize during withdrawal.
Topics: Adult; Alcoholism; Arginine; Diagnostic and Statistical Manual of Mental Disorders; Germany; Homocysteine; Humans; Hyperhomocysteinemia; International Classification of Diseases; Male; Middle Aged; Nitric Oxide Synthase; Pilot Projects; Prospective Studies; Risk Factors; Severity of Illness Index; Substance Withdrawal Syndrome; Time Factors; Vascular Diseases | 2012 |
Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia.
Topics: Animals; Cells, Cultured; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Endostatins; Forkhead Box Protein O3; Forkhead Transcription Factors; Genetic Therapy; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Hypertension, Renovascular; Matrix Metalloproteinase 13; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Renal Artery; Sulfurtransferases; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor A; Vascular System Injuries | 2012 |
Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.
Topics: Animals; Annexin A2; Blood Coagulation; Bone Marrow Transplantation; Disease Models, Animal; Fibrinolysin; Fibrinolysis; Homocysteine; Hyperhomocysteinemia; Leukemia, Promyelocytic, Acute; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Recombinant Proteins; Tissue Plasminogen Activator | 2012 |
Relationship between plasma homocysteine and the morphological and immunohistochemical study of carotid plaques in patients with carotid stenosis over 70%.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carotid Arteries; Carotid Stenosis; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Immunohistochemistry; Incidence; Male; Middle Aged; Plaque, Atherosclerotic; Prevalence; Risk Factors; Severity of Illness Index; Spain | 2012 |
Evidence that AKT and GSK-3β pathway are involved in acute hyperhomocysteinemia.
Topics: Animals; Cell Nucleus; Cytosol; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Homocysteine; Hyperhomocysteinemia; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; tau Proteins; Time Factors | 2012 |
Increased homocysteinemia is associated with beneficial effects on body weight after long-term high-protein, low-fat diet in rats.
Topics: Adipose Tissue; Animals; Diet, Fat-Restricted; Dietary Proteins; Energy Intake; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Obesity; Rats; Rats, Long-Evans; Weight Gain | 2012 |
The influence of homocysteine and oxidative stress on pregnancy outcome.
Topics: Biomarkers; C-Reactive Protein; Ceruloplasmin; Female; Homocysteine; Humans; Hyperhomocysteinemia; Malondialdehyde; Oxidative Stress; Placenta Diseases; Pregnancy; Pregnancy Outcome; Romania; Uric Acid | 2012 |
[Hyperhomocysteinemia and plasma acute-phase proteins in patients with type 2 diabetes mellitus and severe course of atherosclerosis after vascular operations].
Topics: Atherosclerosis; C-Reactive Protein; Diabetes Mellitus, Type 2; Disease Progression; Female; Fibrinogen; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Male; Middle Aged; Postoperative Complications; Risk Assessment; Severity of Illness Index; Statistics as Topic; Vascular Surgical Procedures | 2011 |
Homocysteine and cardiovascular risk: the perils of reductionism in a complex system.
Topics: Animals; Coronary Disease; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk; Vitamin B Complex | 2012 |
Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia.
Topics: Animals; Apoptosis Regulatory Proteins; Blotting, Western; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Chromatography, Gel; Cytoskeletal Proteins; Diet; Folic Acid; Homocysteine; Hyperhomocysteinemia; Inflammasomes; Interleukin-1beta; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Electron, Transmission; NLR Family, Pyrin Domain-Containing 3 Protein; Podocytes; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sclerosis; Vascular Endothelial Growth Factor A | 2012 |
Perfluorooctanoic acid exposure is associated with elevated homocysteine and hypertension in US adults.
Topics: Adult; Blood Pressure; Caprylates; Cross-Sectional Studies; Environmental Exposure; Female; Fluorocarbons; Hazardous Substances; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Nutrition Surveys; Odds Ratio; Risk Factors; United States; Young Adult | 2012 |
Association between endothelial nitric oxide gene intron 4a4b VNTR polymorphism and plasma homocysteine concentrations in Tunisian male patients with myocardial infarction.
Topics: Adult; Alleles; Coronary Artery Disease; Endothelium, Vascular; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Introns; Male; Middle Aged; Myocardial Infarction; Nitric Oxide; Nitric Oxide Synthase Type III; Polymerase Chain Reaction; Polymorphism, Genetic; Tunisia | 2012 |
Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians.
Topics: Adult; Cholesterol; Coronary Artery Disease; Female; Folic Acid; Genetic Association Studies; Homocysteine; Humans; Hyperhomocysteinemia; India; Lipoproteins, HDL; Lipoproteins, LDL; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Smoking; Triglycerides; Vitamin B 12 | 2012 |
Plasma phospholipid polyunsaturated fatty acids and homocysteine in Chinese type 2 diabetes patients.
Topics: Adult; Aged; Algorithms; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Outpatient Clinics, Hospital; Phospholipids; Prevalence; Vitamin B 12 | 2012 |
The effects of berberine on hyperhomocysteinemia and hyperlipidemia in rats fed with a long-term high-fat diet.
Topics: Animals; Aorta; Apolipoproteins; Atherosclerosis; Berberine; Cholesterol; Cholesterol, LDL; Diet, High-Fat; Drug Evaluation, Preclinical; Homocysteine; Hydroxymethylglutaryl CoA Reductases; Hyperhomocysteinemia; Hyperlipidemias; Hypolipidemic Agents; Lipids; Liver; Male; Rats; Rats, Sprague-Dawley; Receptors, Lipoprotein; Risk Factors | 2012 |
Elevated homocysteine is associated with poorer self-perceived physical health in older men: the Health in Men Study.
Topics: Aged; Aged, 80 and over; Confidence Intervals; Genotype; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Perception; Polymorphism, Genetic; Quality of Life; Regression Analysis | 2012 |
Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline Deficiency; Dietary Supplements; Enzyme Inhibitors; Folic Acid; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Wistar; Sarcosine | 2012 |
Factors contributing to the resistivity of a higher casein diet against choline deficiency-induced hyperhomocysteinemia in rats.
Topics: Animals; Caseins; Choline; Choline Deficiency; Diet; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2012 |
The polyphenol-rich extracts from black chokeberry and grape seeds impair changes in the platelet adhesion and aggregation induced by a model of hyperhomocysteinemia.
Topics: Adult; Antioxidants; Blood Platelets; Cardiovascular Diseases; Collagen; Dietary Supplements; Fibrinogen; Fruit; Grape Seed Extract; Homocysteine; Humans; Hyperhomocysteinemia; Photinia; Plant Extracts; Platelet Activation; Platelet Aggregation Inhibitors; Polyphenols; Seeds; Superoxides; Vitis; Young Adult | 2013 |
Chronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood-brain barrier leakage in rats in vivo.
Topics: Animals; Blood-Brain Barrier; Cholesterol; Cholinergic Neurons; Dietary Supplements; Disease Models, Animal; Ethanol; Homocysteine; Hypercholesterolemia; Hyperhomocysteinemia; Inflammation; Male; Maze Learning; Memory Disorders; Rats; Rats, Sprague-Dawley; Risk Factors; Space Perception; Time Factors | 2012 |
Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults.
Topics: Adult; Aged; Betaine-Homocysteine S-Methyltransferase; Cholesterol Ester Transfer Proteins; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Predictive Value of Tests; Reference Values; Retinol-Binding Proteins, Cellular; Risk Factors; Scavenger Receptors, Class B; Serine C-Palmitoyltransferase; Sex Distribution | 2012 |
Association between plasma homocysteine and myocardial SPECT abnormalities in patients referred for suspected myocardial ischaemia.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Body Mass Index; Cardiotonic Agents; Chi-Square Distribution; Coronary Artery Disease; Exercise Test; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Myocardial Ischemia; Myocardial Perfusion Imaging; Odds Ratio; Predictive Value of Tests; Prospective Studies; Referral and Consultation; Risk Assessment; Risk Factors; Severity of Illness Index; South Africa; Stroke Volume; Tomography, Emission-Computed, Single-Photon; Up-Regulation; Vasodilator Agents; Ventricular Function, Left | 2012 |
Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells.
Topics: Animals; Aorta; Atherosclerosis; Cell Proliferation; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Endothelium, Vascular; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Rats; RNA Interference; RNA, Small Interfering; Signal Transduction; Sp1 Transcription Factor; Tunica Intima | 2012 |
Higher plasma homocysteine is associated with lower vitamin B6 status in critically ill surgical patients.
Topics: Aged; Critical Illness; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intensive Care Units; Male; Middle Aged; Nutritional Status; Postoperative Complications; Prevalence; Pyridoxal Phosphate; Vitamin B 12; Vitamin B 6 Deficiency; Vitamin B Complex | 2012 |
Aspirin decreases the risk of depression in older men with high plasma homocysteine.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Aspirin; Australia; Cross-Sectional Studies; Depression; Depressive Disorder; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Platelet Aggregation Inhibitors; Risk; Vitamin B Complex | 2012 |
Relative importance of risk factors for coronary heart disease--the Hordaland Homocysteine study.
Topics: Adult; Age Factors; Aged; Biomarkers; Chi-Square Distribution; Cholesterol; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Myocardial Infarction; Norway; Proportional Hazards Models; Risk Assessment; Risk Factors; Sex Factors; Time Factors; Triglycerides | 2012 |
Homocysteine alters cerebral microvascular integrity and causes remodeling by antagonizing GABA-A receptor.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Cerebrovascular Circulation; Cystathionine beta-Synthase; GABA-A Receptor Agonists; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinases; Mice; Mice, Transgenic; Muscimol; Receptors, GABA-A; Tissue Inhibitor of Metalloproteinases | 2012 |
Homocysteine, a marker of cardiovascular disease risk, is markedly elevated in patients with gout.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Female; Gout; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Factors | 2013 |
Phenolic fractions from Trifolium pallidum and Trifolium scabrum aerial parts in human plasma protect against changes induced by hyperhomocysteinemia in vitro.
Topics: Adult; Antioxidants; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Oxidative Stress; Phenols; Plant Components, Aerial; Prothrombin Time; Thiobarbituric Acid Reactive Substances; Thrombin Time; Trifolium | 2012 |
Relationship between homocysteine and non-dipper pattern in patients with type 2 diabetes mellitus.
Topics: Blood Glucose; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Circadian Rhythm; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2012 |
Dyrk1A, a serine/threonine kinase, is involved in ERK and Akt activation in the brain of hyperhomocysteinemic mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cystathionine beta-Synthase; Dyrk Kinases; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; GRB2 Adaptor Protein; Harmine; Homocysteine; Hyperhomocysteinemia; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt | 2013 |
Study of the effect of antiviral therapy on homocysteinemia in hepatitis C virus- infected patients.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; Cholesterol; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Homocysteine; Humans; Hyperhomocysteinemia; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Triglycerides; Young Adult | 2012 |
[Abnormal findings during newborn period of 160 patients with early-onset methylmalonic aciduria].
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Child; Child, Preschool; China; Female; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylmalonic Acid; Neonatal Screening; Retrospective Studies; Vitamin B 12 | 2012 |
Does phase angle correlate with hyperhomocysteinemia? A study of patients with classical homocystinuria.
Topics: Adolescent; Adult; Cysteine; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Life Expectancy; Male; Methionine; Prognosis; Young Adult | 2013 |
Increased plasma homocysteine predicts arrhythmia recurrence after minimally invasive epicardial ablation for nonvalvular atrial fibrillation.
Topics: Aged; Area Under Curve; Atrial Fibrillation; Biomarkers; Catheter Ablation; Electrocardiography, Ambulatory; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Prospective Studies; Recurrence; Risk Assessment; Risk Factors; ROC Curve; Thoracotomy; Time Factors; Treatment Outcome; Up-Regulation | 2013 |
C677T methylenetetrahydrofolate reductase gene polymorphism as a risk factor involved in venous thromboembolism: a population-based case-control study.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Venous Thromboembolism | 2012 |
Homocysteine concentration and the risk of death in the adult Polish population.
Topics: Adult; Cardiovascular Diseases; Cause of Death; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Longitudinal Studies; Male; Middle Aged; Poland; Population Surveillance; Risk Factors; Smoking; Surveys and Questionnaires; Survival Rate | 2012 |
Elevated plasma homocysteine level is not primarily related to Alzheimer's disease.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Homocysteinemia in mice with genetic betaine homocysteine S-methyltransferase deficiency is independent of dietary folate intake.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Body Weight; Cysteine; Diet; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Mice; Mice, Knockout; Organ Size | 2012 |
Plasma ω-3 fatty acid levels negatively and ω-6 fatty acid levels positively associated with other cardiovascular risk factors including homocysteine in severe obese subjects.
Topics: Adult; Algorithms; Body Mass Index; Cardiovascular Diseases; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Middle Aged; Obesity; Risk Factors; Severity of Illness Index; Turkey; Vitamin B 12 Deficiency; Young Adult | 2012 |
The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Cholesterol, Dietary; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression; Homocysteine; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Male; Methionine; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2012 |
The impact of genetic and environmental factors on homocysteine levels in preterm neonates.
Topics: Cohort Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Infant, Premature; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide | 2013 |
Acid sphingomyelinase gene knockout ameliorates hyperhomocysteinemic glomerular injury in mice lacking cystathionine-β-synthase.
Topics: Animals; Cells, Cultured; Ceramides; Cystathionine beta-Synthase; Genotype; Homocysteine; Hyperhomocysteinemia; Kidney Diseases; Kidney Glomerulus; Male; Mice; Mice, Knockout; Oxidative Stress; Podocytes; Sphingomyelin Phosphodiesterase; Vascular Endothelial Growth Factor A | 2012 |
Relationship of cognitive function with B vitamin status, homocysteine, and tissue factor pathway inhibitor in cognitively impaired elderly: a cross-sectional survey.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Mental Status Schedule; Neuropsychological Tests; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Lack of significant association between Helicobacter pylori infection and homocysteine levels in patients with cardiac syndrome X.
Topics: Adult; Aged; Antibodies, Bacterial; Biomarkers; Case-Control Studies; Chi-Square Distribution; Enzyme-Linked Immunosorbent Assay; Female; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Hyperhomocysteinemia; Immunoglobulin G; Male; Microvascular Angina; Middle Aged; Up-Regulation | 2012 |
[Metabolic interactions between the hyperhomocysteinemia and angiotensin-1 converting enzyme activity in Tunisian patients with coronary heart disease].
Topics: Adult; Aged; Case-Control Studies; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Peptidyl-Dipeptidase A; Risk Factors; Tunisia | 2012 |
Homocysteine, frailty, and all-cause mortality in older men: the health in men study.
Topics: Aged; Aged, 80 and over; Cause of Death; Cohort Studies; Cross-Sectional Studies; Frail Elderly; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prospective Studies | 2013 |
Homocysteine induces serum amyloid A3 in osteoblasts via unlocking RGD-motifs in collagen.
Topics: 3T3 Cells; Animals; Base Sequence; beta Catenin; Cell Line; Chemokine CCL5; Collagen Type I; Extracellular Matrix; fas Receptor; Focal Adhesion Kinase 1; Gene Expression; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinase 13; Mice; Models, Biological; Oligopeptides; Osteoblasts; Osteoporosis; Paxillin; Protein Denaturation; RNA, Messenger; RNA, Small Interfering; Serum Amyloid A Protein; Signal Transduction | 2013 |
NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia.
Topics: Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Caspase 1; Cytoskeletal Proteins; Gene Silencing; Homocysteine; Hyperhomocysteinemia; Inflammasomes; Interleukin-1beta; Kidney Glomerulus; Male; Membrane Glycoproteins; Mice; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidases; Podocytes; Superoxides | 2013 |
Plasma homocysteine and vitamin B12 serum levels, red blood cell folate concentrations, C677T methylenetetrahydrofolate reductase gene mutation and risk of recurrent miscarriage: a case-control study in Spain.
Topics: Abortion, Spontaneous; Adult; Case-Control Studies; Erythrocytes; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Odds Ratio; Polymorphism, Single Nucleotide; Spain; Vitamin B 12 | 2013 |
The impact of intratracheally instilled carbon black on the cardiovascular system of rats: elevation of blood homocysteine and hyperactivity of platelets.
Topics: Air Pollutants, Occupational; Animals; Biomarkers; Blood Coagulation; Carcinogens, Environmental; Cardiovascular Diseases; Cardiovascular System; Dose-Response Relationship, Drug; Homocysteine; Hyperhomocysteinemia; Instillation, Drug; Lung; Male; Organ Specificity; Particle Size; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Soot | 2012 |
Plasma homocysteine levels in dry eye patients.
Topics: Dry Eye Syndromes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Luminescent Measurements; Male; Middle Aged; Prospective Studies; Surveys and Questionnaires; Vitamin B 12 | 2013 |
Homocysteine, folate, vitamin B-12, and physical function in older adults: cross-sectional findings from the Singapore Longitudinal Ageing Study.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Gait; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Middle Aged; Mobility Limitation; Postural Balance; Prospective Studies; Singapore; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Hyperhomocysteinaemia predicts the decline in pulmonary function in healthy male smokers.
Topics: Adult; Aged; Cross-Sectional Studies; Follow-Up Studies; Forced Expiratory Volume; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Male; Middle Aged; Regression Analysis; Respiratory Function Tests; ROC Curve; Smoking; Spirometry; Vital Capacity | 2013 |
Acute myocardial infarction in a young patient with hyperhomocysteinaemia.
Topics: Acute Disease; Adult; Betaine; Coronary Vessels; Folic Acid; Heart; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Myocardium; Thrombosis; Troponin; Ventricular Function, Left | 2012 |
Homocysteine and alpha-1 antitrypsin concentration in patients with subclinical hypercortisolemia.
Topics: Adult; Aged; alpha 1-Antitrypsin; Case-Control Studies; Cushing Syndrome; Female; Homocysteine; Humans; Hydrocortisone; Hyperhomocysteinemia; Male; Middle Aged; Thromboembolism | 2012 |
Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.
Topics: Alzheimer Disease; Animals; Betaine; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Male; Memory Disorders; Rats; Rats, Sprague-Dawley | 2013 |
Protection of DDAH2 overexpression against homocysteine-induced impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells.
Topics: Amidohydrolases; Arginine; Cells, Cultured; Endothelium; Gene Expression; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; L-Lactate Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase Type III; Signal Transduction | 2012 |
Palm tocotrienol-rich fraction reduced plasma homocysteine and heart oxidative stress in rats fed with a high-methionine diet.
Topics: Administration, Oral; Animals; Catalase; Cycas; Diet; Dietary Supplements; Folic Acid; Glutathione Peroxidase; Heart; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tocotrienols | 2013 |
The effects of normalizing hyperhomocysteinemia on clinical and operative outcomes in patients with critical limb ischemia.
Topics: Aged; Aged, 80 and over; Amputation, Surgical; Biomarkers; Chi-Square Distribution; Critical Illness; Disease-Free Survival; Drug Therapy, Combination; Endovascular Procedures; Female; Folic Acid; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Kaplan-Meier Estimate; Limb Salvage; Logistic Models; Lower Extremity; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Risk Factors; Time Factors; Treatment Outcome; Vascular Patency; Vitamin B 12; Vitamin B Complex | 2012 |
Different impact of hyperhomocysteinemia on cerebral small vessel ischemia and cervico-cerebral atherosclerosis in non-stroke individuals.
Topics: Aged; Biomarkers; Brain Ischemia; Cerebral Angiography; Cerebral Small Vessel Diseases; Chi-Square Distribution; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Leukoencephalopathies; Logistic Models; Magnetic Resonance Angiography; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Retrospective Studies; Risk Assessment; Risk Factors; Up-Regulation | 2013 |
Tissue-specific relationship of S-adenosylhomocysteine with allele-specific H19/Igf2 methylation and imprinting in mice with hyperhomocysteinemia.
Topics: Alleles; Animals; Base Sequence; Body Weight; Brain; Crosses, Genetic; Diet; DNA Methylation; Female; Genetic Loci; Genomic Imprinting; Homocysteine; Hyperhomocysteinemia; Insulin-Like Growth Factor II; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Organ Specificity; RNA, Long Noncoding; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity | 2013 |
Homocysteine induces energy imbalance in rat skeletal muscle: is creatine a protector?
Topics: Animals; Cell Survival; Citric Acid Cycle; Creatine; Drug Synergism; Energy Metabolism; Female; Glucose; Homocysteine; Hyperhomocysteinemia; Male; Mitochondria; Muscle, Skeletal; Oxidation-Reduction; Rats; Rats, Wistar | 2013 |
Genistein attenuates vascular endothelial impairment in ovariectomized hyperhomocysteinemic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelin-1; Endothelium, Vascular; Estradiol; Female; Genistein; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; In Vitro Techniques; Liver; Malondialdehyde; Muscle Contraction; Nitroprusside; Ovariectomy; Phenylephrine; Rats; Rats, Wistar | 2012 |
Chemical constituents of ambient particulate air pollution and biomarkers of inflammation, coagulation and homocysteine in healthy adults: a prospective panel study.
Topics: Adult; Air Pollution; Biomarkers; Blood Coagulation; China; Cobalt; Environmental Exposure; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation Mediators; Male; Manganese; Nitrates; Particulate Matter; Prospective Studies; Thrombophilia; Urban Health; Vehicle Emissions; Zinc | 2012 |
Why is homocysteine toxic for the nervous and immune systems?
Topics: Animals; Brain Ischemia; Carnosine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Neuroimmunomodulation; Neuroprotective Agents; Parkinson Disease; Pregnancy; Rats; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2013 |
Low and high homocysteine are associated with mortality independent of B group vitamins but interactive with cognitive status in a free-living elderly cohort.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Biomarkers; Cause of Death; Cognition; Cognition Disorders; Diet; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mortality, Premature; Proportional Hazards Models; Smoking; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Vitamin D deficiency and PAD: a close and often overlooked relationship.
Topics: Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Peptides; Peripheral Arterial Disease; Proteins; Vitamin B Complex | 2013 |
Homocysteine induces inflammatory transcriptional signaling in monocytes.
Topics: Cell Differentiation; Cytokines; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; Interferon-gamma; Interleukin-10; Monocytes; Promoter Regions, Genetic; Signal Transduction; Transcription Factors | 2013 |
A possible genetic link between MTHFR genotype and smoking behavior.
Topics: Adult; Behavior, Addictive; Cardiovascular Diseases; Female; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Smoking | 2012 |
Re: 'Vitamin D deficiency and PAD: a close and often overlooked relationship': vitamins and homocysteine metabolism.
Topics: Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Peptides; Peripheral Arterial Disease; Proteins; Vitamin B Complex | 2013 |
Alterations of retinal vasculature in cystathionine-Beta-synthase mutant mice, a model of hyperhomocysteinemia.
Topics: Animals; Blood-Retinal Barrier; Capillary Permeability; Cystathionine beta-Synthase; Disease Models, Animal; Fluorescein Angiography; Fundus Oculi; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Mice; Mice, Mutant Strains; Microscopy, Fluorescence; Retina; Retinal Diseases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A | 2013 |
Plaque image characteristics, hyperhomocysteinemia, and gene polymorphism of homocysteine metabolism-related enzyme (MTHFR C677T) in acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Plaque, Atherosclerotic; Polymorphism, Single Nucleotide | 2013 |
[Correlation between plasma concentrations of homocysteine and diabetic polyneuropathy evaluated with the Semmes-Weinstein monofilament test in patients with type 2 diabetes mellitus].
Topics: Age Factors; Aged; Alcohol Drinking; Cardiovascular Diseases; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Progression; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypesthesia; Hypoglycemic Agents; Hypolipidemic Agents; Male; Middle Aged; Overweight; Physical Examination; Risk Factors; Severity of Illness Index; Smoking; Vitamin B 12 | 2013 |
Prediction of ischemic stroke in young Indians: is thrombophilia profiling a way out?
Topics: Adolescent; Adult; Antithrombin III; Brain Ischemia; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; India; Lupus Coagulation Inhibitor; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Prognosis; Protein C; Protein C Deficiency; Protein S; Protein S Deficiency; Prothrombin; Stroke; Thrombophilia | 2013 |
Homocysteine in occlusive vascular disease: a risk marker or risk factor.
Topics: Adolescent; Adult; Aged; Biomarkers; Case-Control Studies; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Middle Aged; Retrospective Studies; Risk Factors; Vascular Diseases; Vitamin B Complex; Young Adult | 2012 |
Homocysteine in lipoprotein apheresis patients--retrospective data analysis in apheresis center of a university hospital.
Topics: Aged; Analysis of Variance; Biomarkers; Blood Component Removal; Cardiovascular Diseases; Chi-Square Distribution; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Female; Germany; Homocysteine; Hospitals, University; Humans; Hyperhomocysteinemia; Hyperlipidemias; Lipoprotein(a); Lipoproteins; Male; Middle Aged; Prevalence; Retrospective Studies; Risk Factors; Treatment Outcome; Triglycerides; Vitamin B Complex | 2013 |
Homocysteine plasma levels in patients treated with antiepileptic drugs depend on folate and vitamin B12 serum levels, but not on genetic variants of homocysteine metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anticonvulsants; Cystathionine beta-Synthase; Epilepsy; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Tetrahydrofolate Dehydrogenase; Transcobalamins; Vitamin B 12 | 2013 |
Involvement of 5-methyltetrahydrofolate in the amelioration of hyperhomocysteinemia caused by vitamin B(6) deficiency and L-methionine supplementation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Dietary Supplements; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; Tetrahydrofolates; Vitamin B 6; Vitamin B 6 Deficiency | 2013 |
Association between hypocobalaminaemia and hyperhomocysteinaemia in dogs.
Topics: Animals; Breeding; Dog Diseases; Dogs; Female; Folic Acid; Gastrointestinal Diseases; Homocysteine; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Hyperhomocysteinemia and cobalamin deficiency in young Asian Indians in the United States.
Topics: Adult; Diet, Vegetarian; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Hyperhomocysteinemia; India; Malabsorption Syndromes; Male; Sex Factors; United States; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
[The abnormal reaction to post methionine loading test in type diabetes with or without retinopathy].
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Nitrates; Oxidoreductases Acting on CH-NH Group Donors; Time Factors | 2002 |
Folate supplementation after heart transplantation: effects on homocysteine plasma levels and allograft vascular disease.
Topics: Coronary Angiography; Creatinine; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Time Factors; Transplantation, Homologous; Vascular Diseases | 2002 |
Mutations C677T and A1298C of the 5,10-methylenetetrahydrofolate reductase gene and fasting plasma homocysteine levels are not associated with the increased risk of venous thromboembolic disease.
Topics: 3' Untranslated Regions; Activated Protein C Resistance; Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Codon; Factor V; Fasting; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Poland; Prothrombin; Risk Factors; Thrombophilia; Venous Thrombosis | 2002 |
Alcohol abuse: an important cause of severe hyperhomocysteinemia.
Topics: Alcoholism; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2002 |
Homocysteine and cystatin C level changes in haemodialysed patients and connection with cerebro- and cardiovascular complications.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Cystatin C; Cystatins; Diabetes Mellitus, Type 1; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Stroke | 2001 |
Plasma homocysteine concentration changes after renal transplantation in children.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Male; Serum Albumin; Vitamin B 12 | 2002 |
[Frequency of hyperhomocysteinemia in hemodialysis patients with folic acid supplementation].
Topics: Adult; Age Factors; Aged; Female; Folic Acid; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Dialysis; Time Factors; Vitamin B 12 | 2002 |
Hyperhomocysteinemia in rheumatoid arthritis: influence of methotrexate treatment and folic acid supplementation.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Disability Evaluation; Drug Therapy, Combination; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methotrexate; Middle Aged; Surveys and Questionnaires; Treatment Outcome | 2002 |
Hyperhomocysteinemia and venous thromboembolism: a risk factor more prevalent in the elderly and in idiopathic cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Belgium; Case-Control Studies; Fasting; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Prospective Studies; Protein C Deficiency; Pulmonary Embolism; Risk Factors; Thrombophilia; Venous Thrombosis | 2002 |
Methylenetetrahydrofolate reductase gene mutation and hyperhomocysteinemia as a risk factor for coronary heart disease in the Indian population.
Topics: Adult; Coronary Disease; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Vitamin B 12 | 2002 |
Clinical trials testing the homocysteine hypothesis.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Clinical Trials as Topic; Edible Grain; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2002 |
The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Prevalence; Renal Dialysis; Risk Factors | 2002 |
Homocysteine and cardiovascular disease in diabetes mellitus.
Topics: Animals; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Female; Homocysteine; Hyperhomocysteinemia; Male; Nitric Oxide; Rabbits; Rats; Rats, Inbred Strains; Risk Factors; Sensitivity and Specificity; Severity of Illness Index | 2002 |
Is diabetic hypercoagulability an acquired annexinopathy? Glycation of annexin II as a putative mechanism for impaired fibrinolysis in diabetic patients.
Topics: Animals; Annexin A2; Clinical Trials, Phase III as Topic; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Fibrinolysis; Glycation End Products, Advanced; Glycosylation; Homocysteine; Hyperhomocysteinemia; Lipoprotein(a); Plasminogen; Risk Factors; Thrombophilia; Tissue Plasminogen Activator | 2002 |
Effect of hyperhomocysteinemia on plasma or tissue adenosine levels and renal function.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Fluorescence; Hemodynamics; Homocysteine; Hydrolases; Hyperhomocysteinemia; Kidney; Rats; Rats, Sprague-Dawley; Reference Standards; Risk Factors; Tubercidin | 2002 |
Vascular responses in male and female hypertensive rats with hyperhomocysteinemia.
Topics: Animals; Blood Pressure; Culture Techniques; Endothelium, Vascular; Estradiol; Female; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Methionine; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Sex Factors; Vasoconstriction; Vasodilation | 2002 |
Hyperhomocysteinemia in children with renal transplants.
Topics: Adolescent; Blood Glucose; Child; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Regression Analysis; Vitamin B 12 | 2002 |
Effects of pinealectomy on the levels and the circadian rhythm of plasma homocysteine in rats.
Topics: Aged; Aging; Animals; Circadian Rhythm; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pineal Gland; Rats; Risk Factors | 2002 |
Homocysteine: a risk factor for cardiovascular disease in subclinical hypothyroidism?
Topics: Adult; Aged; Arteriosclerosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypothyroidism; Male; Middle Aged; Myocardial Infarction; Risk Factors; Thyrotropin; Thyroxine | 2002 |
The effect of vitamin B6 and folate supplements on plasma homocysteine and serum lipids levels in patients on regular hemodialysis.
Topics: Adult; Aged; Body Mass Index; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipids; Male; Middle Aged; Renal Dialysis; Risk Factors; Vitamin B 6 | 2001 |
Renal tubulointerstitial injury in weanling rats with hyperhomocysteinemia.
Topics: Age Factors; Animal Feed; Animals; Choline; Folic Acid; Homocysteine; Hyperhomocysteinemia; Methionine; Nephritis, Interstitial; Rats; Rats, Inbred F344; Weaning | 2002 |
[Nutritional determinants of homocysteinemia].
Topics: Adult; Aged; Diet; Diet, Vegetarian; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B Complex | 2002 |
Homocysteine, stroke, and dementia.
Topics: Aging; Alzheimer Disease; Causality; Comorbidity; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Vitamin B Complex | 2002 |
Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland.
Topics: Aged; Alleles; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Comorbidity; Dementia, Vascular; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Northern Ireland; Nutritional Status; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Risk Assessment; Risk Factors; Statistical Distributions; Stroke | 2002 |
Hyperhomocysteinemia: a potential risk factor for cervical artery dissection following chiropractic manipulation of the cervical spine.
Topics: Adult; Arteries; Carotid Artery, Internal, Dissection; Cervical Vertebrae; Disease Susceptibility; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Manipulation, Chiropractic; Middle Aged; Risk Factors; Vertebral Artery Dissection | 2002 |
Evaluation of the DPC IMMULITE 2000 assay for total homocysteine in plasma.
Topics: Chemistry, Clinical; Evaluation Studies as Topic; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Methylmalonic Acid; Quality Control | 2002 |
Role of impaired renal function as a cause of elevated plasma homocysteine concentration in psychogeriatric patients.
Topics: Age Factors; Aged; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Mental Disorders; Predictive Value of Tests; Vitamin B 12 | 2002 |
Homocysteine, folate and vitamin B12 as risk factors for acute myocardial infarction in a Southeast Asian population.
Topics: Adult; Aged; Asian People; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Logistic Models; Male; Middle Aged; Myocardial Infarction; Risk Factors; Seroepidemiologic Studies; Singapore; Vitamin B 12 | 2002 |
Association of hyperhomocysteinemia with plasma sulfate and urine sulfate excretion in patients with progressive renal disease.
Topics: Analysis of Variance; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Proteinuria; Sulfates; Urea | 2002 |
Serum folate and homocysteine levels in head and neck squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Disease Progression; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Hyperhomocysteinemia; Neopterin; Prognosis; Risk Factors | 2002 |
Plasmatic homocysteine concentration and its relationship with complications associated to diabetes mellitus.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis | 2002 |
[The role of hyperhomocysteinemia on atherosclerosis in patients with chronic renal failure].
Topics: Adult; Arteriosclerosis; Carotid Arteries; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Regression Analysis | 2002 |
Helicobacter pylori infection does not affect the serum level of homocysteine.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Coronary Artery Disease; Female; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Sex Factors | 2002 |
Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: role of chemokine and adhesion molecules.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cell Adhesion Molecules; Chemokine CCL2; Chemokines; Diet; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Macrophages; Male; Monocytes; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Vascular Cell Adhesion Molecule-1 | 2002 |
Platelet activity and in vivo arterial thrombus formation in rats with mild hyperhomocysteinaemia.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Homocysteine; Hyperhomocysteinemia; Male; Platelet Activation; Platelet Count; Rats; Rats, Wistar; Thrombosis | 2002 |
Hyperhomocysteinaemia and risk of thrombosis in systemic lupus erythematosus patients.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kuwait; Lupus Erythematosus, Systemic; Male; Risk Factors; Thrombosis | 2002 |
Plasma homocysteine level and uveitis in Behçet's disease.
Topics: Adolescent; Adult; Behcet Syndrome; C-Reactive Protein; Case-Control Studies; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Male; Middle Aged; Retinal Vein Occlusion; Retinoblastoma; Risk Factors | 2002 |
Association between serum aspartate transaminase and homocysteine levels in hemodialysis patients.
Topics: Aspartate Aminotransferases; Female; Folic Acid; Forecasting; Hepatitis B Antibodies; Hepatitis B Antigens; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Renal Dialysis; Uremia; Vitamin B Complex | 2002 |
Effect of methylenetetrahydrofolate reductase 677C-->T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; DNA Primers; Female; Genotype; Hematologic Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Platelet Count; Polymerase Chain Reaction; Polymorphism, Genetic | 2003 |
Does short-term smoking cessation reduce plasma total homocysteine concentrations?
Topics: Adult; Body Mass Index; Cholesterol, HDL; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Random Allocation; Risk Factors; Smoking; Smoking Cessation | 2002 |
Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Female; Ferredoxin-NADP Reductase; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Middle Aged; Polymorphism, Genetic | 2003 |
Hyperhomocysteinemia and vitamin B-12 deficiency are more striking in Syrians than in Germans--causes and implications.
Topics: Adult; Arabs; Cholesterol, LDL; Coronary Disease; Female; Germany; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Prevalence; Syria; Vitamin D Deficiency | 2003 |
Statins and homocysteine.
Topics: Atorvastatin; Heptanoic Acids; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Pyrroles; Risk Factors; Simvastatin | 2003 |
Deficiency of glutathione peroxidase-1 sensitizes hyperhomocysteinemic mice to endothelial dysfunction.
Topics: Animals; Aorta, Thoracic; Carotid Arteries; Catalase; Diet; Endothelium, Vascular; Ethidium; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Superoxide Dismutase; Superoxides; Vasomotor System | 2002 |
Moderate hyperhomocysteinaemia and immune activation in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neopterin; Parkinson Disease; Vitamin B 12 | 2002 |
Associations of plasma homocysteine concentration in subjects with type 2 diabetes mellitus.
Topics: Albuminuria; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osmolar Concentration | 2002 |
Plasma total homocysteine, folate, and vitamin B12 status in Korean adults.
Topics: Adult; Age Factors; Aged; Area Under Curve; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Korea; Male; Middle Aged; Nutritional Status; Prevalence; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
[Therapy of hyperhomocysteinemia with vitamin B12].
Topics: Adult; Diet, Vegetarian; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
The effect of folic acid, vitamin B6 and vitamin B12 on the homocysteine levels in rabbits fed by methionine-enriched diets.
Topics: Animals; Diet; Dose-Response Relationship, Drug; Drug Combinations; Female; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rabbits; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2002 |
Hyperhomocysteinemia is related to a decreased blood level of vitamin B12 in the second and third trimester of normal pregnancy.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intrinsic Factor; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Receptors, Peptide; Statistics as Topic; Vitamin B 12 | 2002 |
Cystathionine beta-synthase polymorphisms and hyperhomocysteinaemia: an association study.
Topics: Adult; Cystathionine beta-Synthase; Fasting; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Vascular Diseases | 2003 |
Hyperhomocysteinemia as a new risk factor for brain shrinkage in patients with alcoholism.
Topics: Adult; Alcoholism; Atrophy; Case-Control Studies; Female; Hippocampus; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Regression Analysis; Risk Factors | 2003 |
Elevated plasma homocysteine levels in patients treated with levodopa: association with vascular disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Risk Factors; Vitamin B 12 | 2003 |
Peroxisome proliferator ameliorates endothelial dysfunction in a murine model of hyperhomocysteinemia.
Topics: Animals; Aorta; Blood Pressure; Clofibric Acid; Cystathionine beta-Synthase; Endothelium, Vascular; Enzyme Activation; Fibric Acids; Genotype; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Peroxisome Proliferators; Phenotype; Proteinuria; Tyrosine | 2003 |
Vitamin B-12 metabolism in HIV-infected patients in the age of highly active antiretroviral therapy: role of homocysteine in assessing vitamin B-12 status.
Topics: Adult; Antiretroviral Therapy, Highly Active; Diagnosis, Differential; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutrition Assessment; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Dose-Response Relationship, Drug; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Mice; Mice, Knockout; Models, Biological; Oxidoreductases; Phosphorylcholine | 2003 |
Stroke in young patients with hyperhomocysteinemia due to cystathionine beta-synthase deficiency.
Topics: Adolescent; Adult; Age Factors; Amino Acid Substitution; Cells, Cultured; Cerebral Infarction; Cystathionine beta-Synthase; DNA Mutational Analysis; Female; Fibroblasts; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mutation; Retinal Artery Occlusion; Stroke | 2003 |
Hyperhomocysteinaemia: time to screen and treat?
Topics: Animals; Antioxidants; Child; Evidence-Based Medicine; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; New Zealand; Randomized Controlled Trials as Topic; Risk Factors; Survival Rate; Vitamins | 2002 |
Folate status and a new repletion cut-off value in a group of healthy Majorcan women.
Topics: Adolescent; Adult; Aged; Female; Fluorescence Polarization Immunoassay; Folic Acid; Gene Frequency; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Radioimmunoassay; Reference Values; Spain | 2003 |
Acquired activated protein C resistance, high tissue factor expression, and hyper-homocysteinemia in systemic lupus erythematosus.
Topics: Activated Protein C Resistance; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lupus Erythematosus, Systemic; Male; Middle Aged; Prevalence; Retrospective Studies; Thromboembolism; Thromboplastin; Thrombosis | 2003 |
[Homocysteine and coronary events in coronary disease patients].
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cause of Death; Creatinine; Disease-Free Survival; Female; Follow-Up Studies; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Myocardial Ischemia; Myocardial Revascularization; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Risk Factors; Survival Analysis | 1999 |
Homocysteine, white matter hyperintensities, and cognition in healthy elderly people.
Topics: Aged; Brain; Cognition; Cognition Disorders; Cross-Sectional Studies; Dementia; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers; Risk Factors | 2003 |
Homocysteine plasma concentration is related to severity of lung impairment in scleroderma.
Topics: Adult; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lung Diseases; Male; Middle Aged; Scleroderma, Systemic; Severity of Illness Index | 2003 |
Hyperhomocystinemia in pseudoexfoliation glaucoma.
Topics: Aged; Chromatography, High Pressure Liquid; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Prospective Studies | 2003 |
Hyperhomocysteinemia induces renal hemodynamic dysfunction: is nitric oxide involved?
Topics: Animals; Cyclic GMP; Homocysteine; Hyperhomocysteinemia; Kidney Diseases; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Renal Circulation; Thiobarbituric Acid Reactive Substances; Tyrosine | 2003 |
Chemical and biomechanical characterization of hyperhomocysteinemic bone disease in an animal model.
Topics: Animals; Blood Chemical Analysis; Bone and Bones; Bone Density; Bone Development; Bone Diseases; Bone Matrix; Chickens; Diet; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Radiography; Tibia | 2003 |
Homocysteine and cognitive function in healthy elderly community dwellers in Italy.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Dementia; Educational Status; Female; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Life Style; Male; Neuropsychological Tests; Odds Ratio; Risk Factors; Socioeconomic Factors | 2003 |
Hyperhomocysteinemia: could the post-methionine oral loading test sometimes be avoided?
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Sensitivity and Specificity; Thrombosis | 2003 |
Serum homocysteine level in Behçet's disease.
Topics: Adult; Behcet Syndrome; Case-Control Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Vitamin B 12 | 2002 |
Plasma homocysteine levels correlated to interactions between folate status and methylene tetrahydrofolate reductase gene mutation in women with unexplained recurrent pregnancy loss.
Topics: Abortion, Habitual; Adolescent; Adult; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy | 2003 |
Hyperhomocysteinemia is associated with the presence of left atrial thrombus in stroke patients with nonvalvular atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Echocardiography, Transesophageal; Female; Heart Atria; Heart Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stroke; Thrombosis | 2003 |
Hyperhomocysteinemia in Asian Indians living in the United States.
Topics: Adult; Area Under Curve; Blood Glucose; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Insulin; Male; Middle Aged; United States; Vitamin B 12; White People | 2003 |
Homocysteine enhances TIMP-1 expression and cell proliferation associated with NADH oxidase in rat mesangial cells.
Topics: Animals; Antioxidants; Cell Division; Cells, Cultured; Collagen Type I; Cyclic N-Oxides; Enzyme Inhibitors; Gene Expression; Glomerular Mesangium; Homocysteine; Hyperhomocysteinemia; Membrane Glycoproteins; Membrane Transport Proteins; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidase 2; NADPH Oxidases; Onium Compounds; Oxidative Stress; Phosphoproteins; Rats; Reactive Oxygen Species; RNA, Messenger; Spin Labels; Tissue Inhibitor of Metalloproteinase-1 | 2003 |
Familial hyperhomocysteinemia: multiple venous thrombosis in four generations of a family.
Topics: Adult; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nitroprusside; Pedigree; Venous Thrombosis; Vitamin B 12; Warfarin | 2003 |
Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nutritional Status; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12 | 2003 |
Homocysteine, folate, vitamin B12 levels, and C677T MTHFR mutation in children with renal failure.
Topics: Adolescent; Child; Child, Preschool; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Predictive Value of Tests; Prevalence; Regression Analysis; Vitamin B 12 | 2003 |
Effect of a methionine-supplemented diet on the blood pressure of Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta; Bradykinin; Cysteine; Dietary Supplements; Endothelium, Vascular; Glutathione; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Methionine; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Systole; Vasodilator Agents | 2003 |
Folate deficiency is a common finding in psychogeriatric patients.
Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Regression Analysis; Vitamin B 12 | 2002 |
Prevalence and mechanisms of hyperhomocysteinemia in elderly hospitalized patients.
Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutritional Status; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
The 677 C-T methylenetetrahydrofolate reductase mutation does not predict increased maternal homocysteine during pregnancy.
Topics: Adult; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Retrospective Studies | 2003 |
Relationship between plasma homocysteine levels and brain atrophy in healthy elderly individuals.
Topics: Aged; Alcohol-Induced Disorders, Nervous System; Alcoholism; Atrophy; Brain Diseases; Chronic Disease; Ethanol; Homocysteine; Humans; Hyperhomocysteinemia | 2003 |
[Hyperhomocysteinemia hastens myocardial infarct and stroke. Prevention.with leaf salads and vitamins].
Topics: Adult; Age Factors; Aged; Arteriosclerosis; Clinical Trials as Topic; Dementia; Diet; Drug Therapy, Combination; Female; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Prospective Studies; Risk Factors; Sex Factors; Stroke; Vegetables; Vitamin B 12; Vitamin B 6 | 2003 |
Genetic evidence that nitric oxide modulates homocysteine: the NOS3 894TT genotype is a risk factor for hyperhomocystenemia.
Topics: Adult; Amino Acid Substitution; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Northern Ireland; Point Mutation; Prospective Studies; Risk Factors; Vitamin B 12 | 2003 |
Low diagnostic value of fasting and post-methionine load homocysteine tests. A study in Dutch subjects with homocysteine test indications.
Topics: Adult; Cardiovascular Diseases; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Netherlands; Prevalence; Reference Values; Retrospective Studies; Risk Factors; Sensitivity and Specificity | 2003 |
Plasma total homocysteine in uncomplicated pregnancy and in preeclampsia.
Topics: Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Vitamin B 12 | 2003 |
Impairment of energy metabolism in hippocampus of rats subjected to chemically-induced hyperhomocysteinemia.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Disease Models, Animal; Electron Transport Complex IV; Energy Metabolism; Glucose; Hippocampus; Homocysteine; Hyperhomocysteinemia; Rats; Rats, Wistar; Succinate Dehydrogenase | 2003 |
Changes in markers of vascular injury in response to transient hyperhomocysteinemia.
Topics: Adult; Animals; Biomarkers; Blood Vessels; Enzyme-Linked Immunosorbent Assay; Female; Fibronectins; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Mice; Mice, Transgenic; Vascular Cell Adhesion Molecule-1 | 2003 |
Homocysteine and risk of recurrent stroke.
Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Brain Ischemia; Cerebral Hemorrhage; Comorbidity; Denmark; Diabetes Mellitus; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Ischemic Attack, Transient; Male; Middle Aged; Odds Ratio; Prospective Studies; Recurrence; Risk; Risk Factors; Smoking; Stroke | 2003 |
Determinants and distributions of plasma total homocysteine concentrations among school children in Taiwan.
Topics: Adolescent; Age Factors; Anthropometry; Cardiovascular Diseases; Child; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Schools; Sex Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Fasting vs nonfasting plasma homocysteine concentrations for diagnosis of hyperhomocysteinemia.
Topics: Adult; Circadian Rhythm; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2003 |
Hyperhomocysteinemia and vitamin score: correlations with silent brain ischemic lesions and brain atrophy.
Topics: Aged; Aged, 80 and over; Atrophy; Brain; Brain Ischemia; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 6; Vitamins | 2003 |
Determinants of hyperhomocysteinemia in patients with chronic liver disease and after orthotopic liver transplantation.
Topics: Adult; Area Under Curve; Case-Control Studies; Chronic Disease; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases; Liver Transplantation; Male; Metabolic Clearance Rate; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2003 |
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice.
Topics: Animals; Betaine; Central Nervous System Depressants; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Fatty Liver, Alcoholic; Gastrointestinal Agents; Gene Expression; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis | 2003 |
[Hyperhomocysteinemia and advancement of atherosclerosis in patients with chronic renal failure on maintenance hemodialysis].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors | 2002 |
Relations between molecular and biological abnormalities in 11 families from siblings affected with methylenetetrahydrofolate reductase deficiency.
Topics: Child; Female; Folic Acid; Genes, Recessive; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolism, Inborn Errors; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; RNA Splice Sites | 2003 |
Vitamin B12 and folate status of older New Zealand women.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; New Zealand; Nutritional Status; Prevalence; Vitamin B 12 | 2003 |
TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the cevelopment of atherosclerosis in hyperhomocysteinemia.
Topics: Animals; Apoptosis; Arteriosclerosis; Blotting, Northern; Cell Adhesion; Cell Nucleus; Cells, Cultured; Cloning, Molecular; Crosses, Genetic; DNA, Complementary; Endoplasmic Reticulum; Endothelium, Vascular; Fluorescent Antibody Technique, Indirect; Gene Expression Profiling; Gene Library; Homocysteine; Humans; Hyperhomocysteinemia; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphorylation; Protein Binding; Protein Structure, Tertiary; RNA, Messenger; Subcellular Fractions; Time Factors; Tissue Distribution; Transcription Factors; Transcriptional Activation; Transfection; Tunicamycin; Umbilical Veins | 2003 |
Hyperhomocysteinemia and oxidative stress during dialysis treatment.
Topics: Adult; Aged; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Risk Factors; Vascular Diseases | 2003 |
[Retinal vein occlusion and hyperhomocysteinemia].
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reference Values; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Vision Disorders | 2003 |
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and the B-vitamins: a facet of nature-nurture interplay.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6 | 2003 |
Hyperhomocysteinemia--case report.
Topics: Adult; Cerebrovascular Disorders; Exophthalmos; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Intellectual Disability | 2003 |
Betaine. Monograph.
Topics: Betaine; Cardiovascular Diseases; Fatty Liver; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Obesity | 2003 |
Relationship between cigarette smoking and novel risk factors for cardiovascular disease in the United States.
Topics: Adult; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cotinine; Cross-Sectional Studies; Dose-Response Relationship, Drug; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Odds Ratio; Smoking; United States | 2003 |
Summaries for patients. Associations between smoking and newer risk factors for cardiovascular disease.
Topics: Adult; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Smoking; United States | 2003 |
The effect of methylenetetrahydrofolate reductase C677T common variant on hypertensive risk is not solely explained by increased plasma homocysteine values.
Topics: Aged; Blood Pressure; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Risk Factors | 2003 |
Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Brachiocephalic Trunk; Diet; Dietary Supplements; Female; Homocysteine; Hyperhomocysteinemia; Lipids; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Vitamins | 2003 |
Levodopa-induced hyperhomocysteinaemia in Parkinson's disease.
Topics: Antiparkinson Agents; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Parkinson Disease | 2003 |
Hyperhomocysteinemia and end-stage renal disease: determinants and association with cardiovascular disease in Tunisian patients.
Topics: Biomarkers; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Renal Dialysis; Risk; Thrombosis | 2003 |
Vitamin B-12 status, particularly holotranscobalamin II and methylmalonic acid concentrations, and hyperhomocysteinemia in vegetarians.
Topics: Adult; Aged; Biomarkers; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Osmolar Concentration; Transcobalamins; Vitamin B 12 | 2003 |
Relationship of systolic blood pressure with plasma homocysteine: importance of smoking status.
Topics: Blood Pressure; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Risk Factors; Smoking | 2003 |
The effects of hyperhomocysteinemia on the presence, extent, and severity of coronary artery disease.
Topics: Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Severity of Illness Index | 2003 |
Plasma homocysteine is elevated in patients with exfoliation syndrome.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Exfoliation Syndrome; Female; Fluorescence Polarization Immunoassay; Glaucoma, Open-Angle; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors | 2003 |
Adverse effect of nitrous oxide in a child with 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Anesthetics, Inhalation; Cells, Cultured; DNA Mutational Analysis; Fatal Outcome; Fibroblasts; Folic Acid; Genes, Recessive; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Infant; Male; Metabolism, Inborn Errors; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nitrous Oxide; Oxidoreductases; Point Mutation; Polymorphism, Genetic; RNA | 2003 |
Hyperhomocysteinemia due to folate deficiency is thrombogenic in rats.
Topics: Animals; Body Weight; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Inbred WKY; Thrombosis | 2003 |
Study on the relationship between plasma homocysteine and acute cerebral vascular disease.
Topics: Cerebral Hemorrhage; Cerebral Infarction; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2000 |
Hyperhomocysteinemia and retinal vascular occlusive disease.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Retinal Artery Occlusion; Retinal Vein Occlusion; Risk Factors | 2003 |
Tetrahydrobiopterin attenuates homocysteine induced endothelial dysfunction.
Topics: Acetylcholine; Animals; Aorta; Biopterins; Calcimycin; Cells, Cultured; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Male; Nitric Oxide; Rats; Rats, Wistar; Superoxides; Vasodilator Agents | 2003 |
Variations in the lipid profile of patients with chronic renal failure, treated with folic acid.
Topics: Arteriosclerosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Erythrocytes; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intravenous; Kidney Failure, Chronic; Lipids; Male; Middle Aged; Renal Dialysis; Triglycerides | 2003 |
Homocysteine is unlikely to be associated with the risk of thromboembolic complications in atrial fibrillation.
Topics: Adult; Age Factors; Aged; Atrial Fibrillation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk; Thromboembolism; Thrombophilia; Ventricular Dysfunction, Left | 2003 |
Homocysteine plasma levels after suspension of vitamin treatment.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Clinical Protocols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B 12 | 2003 |
Elevated plasma homocysteine leads to alterations in fibrin clot structure and stability: implications for the mechanism of thrombosis in hyperhomocysteinemia.
Topics: Animals; Blood Coagulation; Fibrin; Fibrinogen; Fibrinolysin; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Microscopy, Electron, Scanning; Rabbits; Thrombosis | 2003 |
Treatment of hyperhomocysteinemia in pediatric heart transplant recipients.
Topics: Adolescent; Antioxidants; Biomarkers; Child; Child Welfare; Child, Preschool; Combined Modality Therapy; Creatinine; Female; Folic Acid; Follow-Up Studies; Heart Transplantation; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant Welfare; Male; Statistics as Topic; Treatment Outcome; Vitamin A; Vitamin B 12; Vitamin E | 2003 |
TGF-beta1 impairs homocysteine metabolism in human renal cells: possible implications for transplantation.
Topics: Cells, Cultured; Epithelial Cells; Homocysteine; Humans; Hyperhomocysteinemia; Interleukin-1; Interleukin-10; Kidney Transplantation; Kidney Tubules, Proximal; Predictive Value of Tests; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
C-reactive protein, lipoprotein(a), homocysteine, and male sex contribute to carotid atherosclerosis in peritoneal dialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Carotid Artery Diseases; Chronic Disease; Cross-Sectional Studies; Cytokines; Female; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Japan; Kidney Failure, Chronic; Lipoprotein(a); Male; Middle Aged; Parathyroid Hormone; Peritoneal Dialysis; Risk Factors; Sex Factors; Ultrasonography | 2003 |
Memantine in moderate-to-severe Alzheimer's disease.
Topics: Alzheimer Disease; Excitatory Amino Acid Antagonists; Homocysteine; Humans; Hyperhomocysteinemia; Memantine; N-Methylaspartate | 2003 |
Adenosine-the missing link to understanding homocysteine pathogenicity or more smoke on the horizon?
Topics: Adenosine; Cardiovascular Diseases; Cardiovascular System; Homocysteine; Humans; Hyperhomocysteinemia | 2003 |
Homocysteine, pharmacogenetics, and neurotoxicity in children with leukemia.
Topics: Carrier Proteins; Child; Homocysteine; Humans; Hyperhomocysteinemia; Membrane Transport Proteins; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reduced Folate Carrier Protein | 2003 |
Methionine synthase (MTR) 2756 (A --> G) polymorphism, double heterozygosity methionine synthase 2756 AG/methionine synthase reductase (MTRR) 66 AG, and elevated homocysteinemia are three risk factors for having a child with Down syndrome.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alleles; Case-Control Studies; Child; Down Syndrome; Female; Ferredoxin-NADP Reductase; Flavoproteins; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Sicily | 2003 |
Homocysteine and the risk of stroke and thromboembolism in atrial fibrillation: an uncertain role.
Topics: Atrial Fibrillation; Causality; Comorbidity; Homocysteine; Humans; Hyperhomocysteinemia; Risk Assessment; Stroke; Thromboembolism | 2003 |
Vitamins, homocysteine, and cognition.
Topics: Biomarkers; Cognition Disorders; Educational Status; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 Deficiency | 2003 |
Homocysteine and cognitive function in the Sacramento Area Latino Study on Aging.
Topics: Age Factors; Aged; Biomarkers; California; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Educational Status; Female; Hispanic or Latino; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Predictive Value of Tests; Risk Factors; Sex Factors; Vitamin B 12 | 2003 |
Increased plasma homocysteine levels in shift working bus drivers.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Genomics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Occupational Diseases; Risk Factors; Sleep Disorders, Circadian Rhythm; Transportation | 2003 |
Relationships of plasma interleukin-18 concentrations to hyperhomocysteinemia and carotid intimal-media wall thickness in patients with type 2 diabetes.
Topics: Biomarkers; C-Reactive Protein; Carotid Arteries; Carotid Stenosis; Cholesterol; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Homocysteine; Humans; Hyperhomocysteinemia; Interleukin-18; Middle Aged; Reference Values; Tunica Intima; Tunica Media | 2003 |
Homocysteine levels in pediatric renal transplant recipients.
Topics: Adolescent; Age Factors; Cadaver; Child; Child, Preschool; Creatinine; Cross-Sectional Studies; Drug Therapy, Combination; Fasting; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Patient Selection; Tissue Donors | 2003 |
HOMOCYSTINURIA. BIOCHEMICAL STUDIES OF TISSUES INCLUDING A COMPARISON WITH CYSTATHIONINURIA.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Brain; Brain Chemistry; Chemistry Techniques, Analytical; Cystathionine gamma-Lyase; Geriatrics; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Hyperhomocysteinemia; Methionine; Oxidoreductases; Transferases; Urine | 1965 |
S-homocysteinylation of transthyretin is detected in plasma and serum of humans with different types of hyperhomocysteinemia.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Prealbumin; Spectrometry, Mass, Electrospray Ionization | 2003 |
Hyperhomocysteinemia and BRVO.
Topics: Black People; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Retinal Vein Occlusion; Risk Factors | 2003 |
Hyperhomocysteinemia in patients with heart failure referred for cardiac transplantation: preliminary observations.
Topics: Biomarkers; Cardiomyopathies; Coronary Artery Disease; Creatinine; Female; Florida; Folic Acid; Heart Failure; Heart Transplantation; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Oxygen Consumption; Pulmonary Wedge Pressure; Retrospective Studies; Severity of Illness Index; Statistics as Topic; Stroke Volume; Treatment Outcome | 2003 |
The C677T mutation in methylenetetrahydrofolate reductase gene, plasma homocysteine concentration and the risk of coronary artery disease.
Topics: Adult; Aged; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Threonine; Vitamin B 12 | 2003 |
Why should mild hyperhomocysteinemia be responsible for CAD?
Topics: Adolescent; Adult; Aged; Carotid Artery, Internal, Dissection; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Neck; Risk Factors; Vertebral Artery Dissection | 2003 |
The prevalence of MTHFR 677C-->T missense mutation, total plasma homocysteine levels and associated risk factors in Malay subjects.
Topics: Adult; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Malaysia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Risk Factors | 2003 |
Lowering plasma homocysteine.
Topics: Arteriosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2003 |
Hyperhomocystinemia in children with inflammatory bowel disease.
Topics: Adolescent; Aging; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Tetrahydrofolates; Thromboembolism; Vitamin B 12; von Willebrand Factor | 2003 |
Serum homocysteine level is higher in Behçet's disease with vascular involvement.
Topics: Adolescent; Adult; Behcet Syndrome; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Sex Factors; Thrombosis | 2005 |
Plasma homocysteine, hypertension incidence, and blood pressure tracking: the Framingham Heart Study.
Topics: Blood Pressure; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Incidence; Longitudinal Studies; Male; Middle Aged; Prospective Studies | 2003 |
Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction.
Topics: Aged; Biomarkers; Brain Ischemia; Cerebral Infarction; Endothelium, Vascular; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Logistic Models; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Thrombomodulin | 2004 |
Dietary pattern is associated with homocysteine and B vitamin status in an urban Chinese population.
Topics: Adult; Animals; Asian People; China; Diet; Feeding Behavior; Female; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Meat; Urban Population; Vitamin B Complex | 2003 |
Phenotypic variability of cardiovascular manifestations in Marfan Syndrome. Possible role of hyperhomocysteinemia and C677T MTHFR gene polymorphism.
Topics: Adolescent; Adult; Aortic Aneurysm; Aortic Dissection; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Marfan Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Phenotype; Polymorphism, Genetic; Severity of Illness Index | 2003 |
[Alcohol drinking, raised homocysteine level and sequelae].
Topics: Adult; Aged; Alcohol Drinking; Arteriosclerosis; Blood-Brain Barrier; Brain Diseases; Clinical Trials as Topic; Dementia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Risk Factors; Sex Factors; Time Factors | 2003 |
Hyperhomocysteinemia as a component of syndrome X.
Topics: Animals; Blood Pressure; Cholesterol; Diet; Fructose; Homocysteine; Hyperhomocysteinemia; Insulin; Male; Metabolic Syndrome; Rats; Rats, Sprague-Dawley; Triglycerides | 2003 |
To: Looker HC, Fagot-Campagna A, Gunter EW et al. (2003) Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes. Diabetologia 46:766-772.
Topics: Animals; Diabetic Angiopathies; Diabetic Nephropathies; Homocysteine; Humans; Hyperhomocysteinemia; Models, Animal; Rabbits; Risk Factors | 2004 |
[Plasma homocysteine in human immunodeficiency virus infected patient].
Topics: Adult; Anti-HIV Agents; Arteriosclerosis; Biomarkers; Case-Control Studies; Female; Folic Acid; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Male; P-Selectin; Risk Factors; Smoking; Vitamin B 12 | 2003 |
Hyperhomocysteinemia activates nuclear factor-kappaB in endothelial cells via oxidative stress.
Topics: Animals; Aorta; Cells, Cultured; Endothelium, Vascular; Homocysteine; Hyperhomocysteinemia; I-kappa B Kinase; I-kappa B Proteins; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Superoxides | 2004 |
Neurological implications of hyperhomocysteinemia in patients with atherothrombotic disease.
Topics: Brain Ischemia; Coronary Artery Disease; Coronary Thrombosis; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Risk Factors; Stroke | 2003 |
[Serum homocysteine in children and adolescents. Relation with family history of cardiovascular disease].
Topics: Adolescent; Cardiovascular Diseases; Child; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Lipoproteins; Male; Risk Factors; Vitamin B 12 | 2003 |
Incorrect and inconsistent use of homocysteine's nomenclature: a potential source of misunderstandings.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Structure-Activity Relationship; Terminology as Topic | 2003 |
Moderate hyperhomocysteinaemia and immune activation in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antigens, CD; Arthritis, Rheumatoid; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Vitamin B 12 | 2003 |
[Alteration of homocysteine before and after hemodialysis in chronic hemodialysis patients].
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 2003 |
Where are we standing in homocysteine research?
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Research; Risk Factors | 2003 |
Hyperhomocysteinemia and B-vitamin status after discontinuation of oral anticoagulation therapy in patients with a history of venous thromboembolism.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Retrospective Studies; Substance Withdrawal Syndrome; Thromboembolism; Vitamin B 12; Warfarin | 2003 |
The impact of hyperhomocysteinemia as a cardiovascular risk factor in the prediction of coronary heart disease.
Topics: Aged; Biomarkers; C-Reactive Protein; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors | 2003 |
The atherogenic effect of excess methionine intake.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Diet; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Mice; Models, Biological; Vitamin B 12; Vitamin B 6; Vitamin B Deficiency | 2003 |
Restenosis in Intervened Coronaries with Hyperhomocysteinemia (RICH).
Topics: Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; ROC Curve; Stents | 2003 |
Evidence suggests diabetes outcomes linked to homocysteine.
Topics: Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2003 |
Prevalence of hyperhomocysteinemia and the MTHFR C677T polymorphism in patients with arterial and venous thrombosis from North Western Russia.
Topics: Adolescent; Adult; Aged; Blood Coagulation; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymorphism, Genetic; Retrospective Studies; Russia; Thrombosis; Venous Thrombosis | 2003 |
Association of neovascular age-related macular degeneration and hyperhomocysteinemia.
Topics: Aged; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Macular Degeneration; Male; Prospective Studies; Retinal Neovascularization | 2004 |
Hyperhomocysteinemia and other newly recognized inherited coagulation disorders (factor V Leiden and prothrombin gene mutation) in patients with idiopathic cerebral vein thrombosis.
Topics: Adult; Antithrombin III; Cerebral Veins; Factor V; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Point Mutation; Prevalence; Protein C; Protein S; Prothrombin; Risk Factors; Thrombophilia; Venous Thrombosis | 2004 |
[Hyperhomocysteinemia and deep-vein thrombosis].
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Restriction Fragment Length; Venous Thrombosis; Vitamin B 12 | 2003 |
Plasma homocysteine concentrations in adolescents with subclinical hypothyroidism.
Topics: Adolescent; Cholesterol; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypothyroidism; Isoantibodies; Kidney; Kidney Function Tests; Thyroiditis, Autoimmune; Thyrotropin; Thyroxine; Triiodothyronine; Vitamin B 12 | 2003 |
Folate, homocysteine levels, methylenetetrahydrofolate reductase (MTHFR) 677C --> T variant, and the risk of myocardial infarction in young women: effect of female hormones on homocysteine levels.
Topics: Adolescent; Adult; Case-Control Studies; Contraceptives, Oral; Female; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Risk Factors; Vitamin B 12 | 2004 |
Hyperhomocysteinemia and oxidative stress in hemodialysis: effects of supplementation with folic acid.
Topics: Ascorbic Acid; Dietary Supplements; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipid Peroxidation; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Proteins; Renal Dialysis; Vitamin B 12; Vitamin E | 2003 |
Plasma homocysteine in early and late pregnancies complicated with preeclampsia and isolated intrauterine growth restriction.
Topics: Adult; Case-Control Studies; Cohort Studies; Down Syndrome; Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Mass Screening; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Second; Risk Factors | 2004 |
Hyperhomocysteinemia, oxidative stress, and cerebral vascular dysfunction.
Topics: Arginine; Cerebrovascular Circulation; DNA Methylation; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Reactive Oxygen Species; Risk Factors; Stroke | 2004 |
Plasma homocysteine after insulin infusion in type II diabetic patients with and without methionine intolerance.
Topics: Blood Glucose; Cysteine; Diabetes Mellitus, Type 2; DNA; Female; Folic Acid; Glucose Clamp Technique; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymerase Chain Reaction; Vitamin B 12; Vitamin B 6 | 2004 |
Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity.
Topics: Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electric Stimulation; Electrophysiology; Embryo, Mammalian; Homocysteine; Hyperhomocysteinemia; N-Methylaspartate; Neocortex; Nerve Net; Neural Inhibition; Rats; Rats, Wistar; Valine | 2004 |
Opposite effect of methionine-supplemented diet, a model of hyperhomocysteinemia, on plasma and liver antioxidant status in normotensive and spontaneously hypertensive rats.
Topics: Animals; Antioxidants; Biological Availability; Catalase; Copper; Cysteine; Diet; Dietary Supplements; Glutathione; Homocysteine; Hyperhomocysteinemia; Hypertension; Iron; Liver; Male; Methionine; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2004 |
Hyperhomocysteinaemia in treated patients with Huntington's disease homocysteine in HD.
Topics: Adult; Biomarkers; Central Nervous System Agents; Disease Progression; Drug Interactions; Female; Homocysteine; Humans; Huntingtin Protein; Huntington Disease; Hyperhomocysteinemia; Male; Metabolic Clearance Rate; Middle Aged; Mutation; Nerve Tissue Proteins; Neurologic Examination; Nuclear Proteins | 2004 |
L-Homocysteine and L-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells.
Topics: Animals; Cattle; Cells, Cultured; Cysteine; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Glutathione; Glutathione Peroxidase; Homocysteine; Homocystine; Hydrogen Peroxide; Hyperhomocysteinemia; Lipid Peroxidation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III | 2004 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
Topics: Antiparkinson Agents; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylation; Parkinson Disease; S-Adenosylmethionine; Vitamin B Complex | 2004 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
Topics: Antiparkinson Agents; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Neopterin; Parkinson Disease; Vitamin B Complex | 2004 |
Hyperhomocysteinaemia & folic acid supplementation in patients with high risk of coronary artery disease.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Coronary Artery Disease; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Male; Microscopy, Fluorescence; Middle Aged; Risk Factors; Time Factors; Vitamin B 12 | 2004 |
Serum total homocysteine levels and the prevalence of folic acid deficiency and C677T mutation at the MTHFR gene in an indigenous population of Amazonia: the relationship of homocysteine with other cardiovascular risk factors.
Topics: Adult; Brazil; Cardiovascular Diseases; Female; Folic Acid Deficiency; Health Status Indicators; Homocysteine; Humans; Hyperhomocysteinemia; Indians, South American; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors; Sex Factors; Smoking; Vitamin B 12 | 2004 |
Serum total homocysteine levels, folate, and B-vitamins intake and coronary heart disease risk factors among tri-ethnic college students.
Topics: Adult; Black or African American; Coronary Disease; Female; Florida; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Risk Factors; Sex Factors; Smoking; Universities; Vitamin B 12; Vitamin B 6; White People | 2004 |
Risk factors for heart disease.
Topics: Brazil; Cardiovascular Diseases; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Indians, South American; Risk Factors; Vitamin B 12 | 2004 |
Eat right and exercise for lower homocysteine levels and less chance of heart disease.
Topics: Adult; Age Factors; Coronary Disease; Exercise; Feeding Behavior; Female; Florida; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Smoking; Vitamin B 12; Vitamin B 6 | 2004 |
Chinese yam (Dioscorea alata cv. Tainung No. 2) feeding exhibited antioxidative effects in hyperhomocysteinemia rats.
Topics: Animals; Antioxidants; Diet; Dioscorea; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Male; Methionine; Oxidative Stress; Platelet Aggregation; Rats; Rats, Sprague-Dawley | 2004 |
The neuronal SAPK/JNK pathway is altered in a murine model of hyperhomocysteinemia.
Topics: Activating Transcription Factor 2; Animals; Brain; Brain Chemistry; Cyclic AMP Response Element-Binding Protein; Cystathionine beta-Synthase; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Hippocampus; Homocysteine; Hyperhomocysteinemia; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neurons; Oligonucleotide Array Sequence Analysis; Signal Transduction; Transcription Factors | 2004 |
Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study.
Topics: Cardiac Volume; Female; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Middle Aged; Sex Characteristics; Ventricular Dysfunction, Left; Ventricular Remodeling | 2004 |
The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate.
Topics: Analgesics, Opioid; Animals; Caspases; Cell Death; Cell Line; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Homocysteine; Hyperhomocysteinemia; Neurodegenerative Diseases; Neuroprotective Agents; Pentazocine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Retinal Ganglion Cells | 2004 |
Hyperhomocysteinemia in pediatric and young adult renal transplant recipients.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Creatinine; Cross-Sectional Studies; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Logistic Models; Male; Retrospective Studies; Risk Factors; Sex Factors; Tissue Donors | 2004 |
Hyperhomocysteinemia in patients with Behçet's disease: is it due to inflammation or therapy?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; C-Reactive Protein; Colchicine; Drug Therapy, Combination; Eye Diseases; Female; Folic Acid; Glucocorticoids; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Male; Thrombosis; Vitamin B 12 | 2005 |
Mild hyperhomocysteinemia is a risk-factor in all etiological subtypes of stroke.
Topics: Aged; Chromatography, High Pressure Liquid; Diabetes Complications; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Male; Risk Factors; Smoking; Stroke | 2004 |
Endothelial cell adhesion molecules in healthy adults during acute hyperhomocysteinemia and mild hypertriglyceridemia.
Topics: Acute Disease; Administration, Oral; Adult; Cardiovascular Diseases; Cell Adhesion Molecules; Comorbidity; Dietary Fats; Drug Synergism; Endothelium; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertriglyceridemia; Inflammation; Male; Methionine; Middle Aged; P-Selectin; Risk Factors; Triglycerides | 2004 |
Homocysteine and folic acid are inversely related in black women with preeclampsia.
Topics: Adolescent; Adult; Arteriosclerosis; Black People; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Age; Pennsylvania; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; White People | 2004 |
Small artery mechanics in hyperhomocysteinemic mice: effects of angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Collagen; Disease Models, Animal; Elastin; Female; Homocysteine; Hyperhomocysteinemia; Male; Mesenteric Arteries; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Knockout; Vasoconstrictor Agents | 2004 |
The 894 G > T variant of endothelial nitric oxide synthase (eNOS) increases the risk of recurrent venous thrombosis through interaction with elevated homocysteine levels.
Topics: Case-Control Studies; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Molecular Epidemiology; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrosation; Odds Ratio; Polymorphism, Single Nucleotide; Recurrence; Risk; Venous Thrombosis | 2004 |
Hyperhomocysteinaemia in a young woman presenting with stroke, associated with methylene tetrahydrofolate reductase C677T homozygosity.
Topics: Adult; Brain Ischemia; Contraceptives, Oral; Female; Genotype; Heart Septal Defects, Atrial; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Risk Factors; Stroke | 2004 |
Hyperhomocysteinemia and the methylenetetrahydrofolate reductase 677C-T mutation in patients under 50 years of age affected by central retinal vein occlusion.
Topics: Adult; Arteriosclerosis; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Prospective Studies; Retinal Vein Occlusion; Risk Factors | 2004 |
[Hyperhomocysteinemia, oxidative stress and microinflammation in chronic renal failure: their roles in atherogene].
Topics: Adult; Aged; Arteriosclerosis; C-Reactive Protein; Enzyme-Linked Immunosorbent Assay; Female; Fluorescence Polarization Immunoassay; Glutathione Peroxidase; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-6; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Spectrophotometry; Tumor Necrosis Factor-alpha | 2004 |
Hyperhomocysteinemia in patients with diabetes mellitus with and without diabetic retinopathy.
Topics: Aged; Blood Glucose; Cardiovascular Diseases; Case-Control Studies; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Prospective Studies; Time Factors | 2004 |
Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency.
Topics: Animal Feed; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Cysteine; Female; Heterozygote; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Liver; Male; Methionine; Methyltransferases; Mice; Mice, Inbred C57BL; Regression Analysis; Serine | 2004 |
Homocysteine, vitamins, and prevention of vascular disease.
Topics: Animals; Arteriosclerosis; Dietary Proteins; Homocysteine; Humans; Hyperhomocysteinemia; Models, Theoretical; Risk Factors; Vitamin B Complex | 2004 |
Elevated levels of plasma homocysteine are associated with neurotoxicity.
Topics: Aged; Biomarkers; Comorbidity; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurotoxicity Syndromes; Probability; Risk Assessment; Sampling Studies; Sensitivity and Specificity; Statistics, Nonparametric | 2004 |
Homocysteine levels and the risk of osteoporotic fracture.
Topics: Aged; Bone Density; Cohort Studies; Female; Follow-Up Studies; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osteoporosis; Proportional Hazards Models; Risk; Risk Factors | 2004 |
Homocysteine as a predictive factor for hip fracture in older persons.
Topics: Aged; Aged, 80 and over; Female; Follow-Up Studies; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Osteoporosis; Proportional Hazards Models; Risk Factors | 2004 |
Homocysteine and osteoporotic fractures--culprit or bystander?
Topics: Estradiol; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors | 2004 |
Selective adsorption of homocysteine using an HFR-ON LINE technique.
Topics: Adsorption; Adult; Equipment Design; Equipment Safety; Female; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Probability; Sampling Studies; Sensitivity and Specificity; Statistics, Nonparametric; Treatment Outcome | 2004 |
Hyperhomocysteinemia: marker of systemic atherosclerosis in peripheral arterial disease.
Topics: Aged; Arteriosclerosis; Biomarkers; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Peripheral Vascular Diseases; Prospective Studies | 2004 |
Fibrate treatment and prevalence risk of mild hyperhomocysteinaemia in clinical coronary heart disease patients.
Topics: Case-Control Studies; Coronary Disease; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Hypolipidemic Agents; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prevalence; Retrospective Studies; Vitamin B 12 | 2004 |
Plasma homocysteine levels and risk of Alzheimer disease.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Comorbidity; Confounding Factors, Epidemiologic; Cross-Sectional Studies; Cysteine; Dementia; Diabetes Mellitus; Ethnicity; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Neuropsychological Tests; New York City; Prevalence; Risk Factors; Sampling Studies; Stroke; Vitamin B 12; Vitamin B 6 | 2004 |
Plasma homocysteine levels in living kidney donors before and after uninephrectomy.
Topics: Adult; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertrophy; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Living Donors; Male; Middle Aged; Nephrectomy | 2004 |
Hyperhomocyst(e)inemia and elevated soluble vascular cell adhesion molecule-1 concentrations are associated with an increased risk of preeclampsia.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Odds Ratio; Pre-Eclampsia; Pregnancy; Risk Factors; Vascular Cell Adhesion Molecule-1 | 2004 |
Prothrombin gene mutation G20210A, homocysteine, antiphospholipid antibodies and other hypercoagulable states in ocular thrombosis.
Topics: Activated Protein C Resistance; Aged; Antibodies, Anticardiolipin; Child; Eye Diseases; Factor V; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lupus Coagulation Inhibitor; Male; Middle Aged; Point Mutation; Protein C; Prothrombin; Thrombosis | 2004 |
Polymorphisms in the methylenetetrahydrofolate reductase and methionine synthase reductase genes and homocysteine levels in Brazilian children.
Topics: Brazil; Child; Child, Preschool; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2004 |
Effect of experimental hyperhomocysteinemia on cardiac structure and function in the rat.
Topics: Animals; Echocardiography; Heart; Homocysteine; Hyperhomocysteinemia; Male; Rats; Ventricular Remodeling | 2004 |
The new kid on the block: the unfolded protein response in the pathogenesis of atherosclerosis.
Topics: Animals; Apoptosis; Arteriosclerosis; Cholesterol; Endoplasmic Reticulum; Endothelial Cells; Homocysteine; Humans; Hyperhomocysteinemia; Macrophages; Oxidative Stress; Protein Folding | 2004 |
Chronic hyperhomocysteinemia provokes a memory deficit in rats in the Morris water maze task.
Topics: Animals; Animals, Newborn; Brain; Escape Reaction; Homocysteine; Hyperhomocysteinemia; Injections, Subcutaneous; Male; Maze Learning; Orientation; Rats; Rats, Wistar; Retention, Psychology | 2004 |
Serum homocysteine concentrations in children with inflammatory bowel disease.
Topics: Adolescent; Child; Child, Preschool; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Risk Factors; Thromboembolism | 2004 |
Homocysteine is an independent risk factor for myocardial infarction, in particular fatal myocardial infarction in middle-aged women.
Topics: Causality; Female; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Myocardial Infarction; Oxidative Stress; Risk Factors | 2004 |
Serum homocysteine and endothelial dysfunction in circulatory disorders in women.
Topics: Arginine; Coronary Disease; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Myocardial Infarction; Nitric Oxide; Risk; Risk Factors | 2004 |
Total homocysteine and cognition in a tri-ethnic cohort: the Northern Manhattan Study.
Topics: Adult; Age Factors; Aged; Apolipoprotein E4; Apolipoproteins E; Black or African American; Cognition; Cognition Disorders; Cohort Studies; Ethnicity; Fasting; Female; Hispanic or Latino; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; New York City; Psychological Tests; Risk Factors; Socioeconomic Factors; Vitamin B 12 Deficiency; White People | 2004 |
Hyperhomocysteinemia in patients with Cushing's syndrome.
Topics: Adult; Aged; Case-Control Studies; Circadian Rhythm; Cushing Syndrome; Cysteine; DNA; Female; Folic Acid; Homocysteine; Humans; Hydrocortisone; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osmolar Concentration; Polymorphism, Genetic; Threonine | 2004 |
High dietary methionine plus cholesterol exacerbates atherosclerosis formation in the left main coronary artery of rabbits.
Topics: Animal Feed; Animals; Arterioles; Cholesterol, Dietary; Coronary Artery Disease; Coronary Vessels; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rabbits; Risk Factors; Tunica Intima; Tunica Media | 2004 |
[Negative regulation of homocysteine metabolism by stress in rats].
Topics: Animals; Down-Regulation; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological | 2004 |
Hyperhomocysteinemia is associated with human coronary atherosclerosis through the reduction of the ratio of endothelium-bound to basal extracellular superoxide dismutase.
Topics: Biomarkers; Coronary Artery Disease; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Risk Factors; Superoxide Dismutase | 2004 |
Hyperhomocysteinemia and the development of chronic kidney disease in a general population: the Hisayama study.
Topics: Aged; Chronic Disease; Cohort Studies; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Risk Factors | 2004 |
Hyperhomocysteinemia in relation to plasma free amino acids, biomarkers of inflammation and mortality in patients with chronic kidney disease starting dialysis therapy.
Topics: Amino Acids; Biomarkers; Chronic Disease; Cross-Sectional Studies; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Kidney Diseases; Male; Malnutrition; Middle Aged; Nutritional Status; Renal Dialysis; Survival Analysis | 2004 |
Homocysteine as a predictive factor for hip fracture in older persons.
Topics: Aged; Bone Density; Confounding Factors, Epidemiologic; Exercise; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors | 2004 |
Homocysteine as a predictive factor for hip fracture in older persons.
Topics: Aged; Aging; Creatinine; Glomerular Filtration Rate; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors | 2004 |
Homocysteine as a predictive factor for hip fracture in older persons.
Topics: Aged; Aging; Bone Density; Folic Acid Deficiency; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors; Vitamin B Deficiency | 2004 |
Homocysteine as a predictive factor for hip fracture in older persons.
Topics: Aged; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Randomized Controlled Trials as Topic; Research Design; Risk Factors | 2004 |
Homocysteine in renal transplant recipients: association with transplant duration and renal function.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Female; Graft Survival; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Transplantation; Male; Middle Aged; Risk Factors | 2004 |
Role of TNF-alpha in ethanol-induced hyperhomocysteinemia and murine alcoholic liver injury.
Topics: Animals; Antigens, CD; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enteral Nutrition; Ethanol; Homocysteine; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Stress, Physiological; Tumor Necrosis Factor-alpha | 2004 |
Folate and cobalamin synergistically decrease the risk of high plasma homocysteine in a nonsupplemented elderly institutionalized population.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Diet; Drug Synergism; Female; Folic Acid; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Risk Factors; Vitamin B 12; Vitamin B Complex | 2004 |
Hyperhomocysteinemia in acute Plasmodium falciparum malaria: an effect of host-parasite interaction.
Topics: Acute Disease; Adult; Age Factors; Animals; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Host-Parasite Interactions; Humans; Hyperhomocysteinemia; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Severity of Illness Index | 2004 |
Coagulation and inflammation in overt diabetic nephropathy: association with hyperhomocysteinemia.
Topics: Albuminuria; alpha-2-Antiplasmin; Biomarkers; Blood Coagulation; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Fibrinogen; Fibrinolysin; Fibrinolysis; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-6; Linear Models; Male; Middle Aged; Protein C | 2004 |
Folate therapy and in-stent restenosis.
Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Coronary Restenosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stents; Vitamin B 6; Vitamin B Complex | 2004 |
Elevated serum homocysteine levels for gouty patients.
Topics: Adult; Allopurinol; Arthritis, Gouty; Case-Control Studies; Gout Suppressants; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Risk Factors | 2005 |
Acute hyperhomocysteinemia decreases NO bioavailability in healthy adults.
Topics: Adult; Biological Availability; Female; Glutathione Peroxidase; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Lipoproteins, LDL; Male; Nitric Oxide; Oxidation-Reduction; Reactive Oxygen Species | 2004 |
Hyperkeratosis in cystathionine beta synthase-deficient mice: an animal model of hyperhomocysteinemia.
Topics: Animals; Cystathionine beta-Synthase; Heterozygote; Homocysteine; Homozygote; Hyperhomocysteinemia; Keratosis; Mice; Mice, Knockout | 2004 |
Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population.
Topics: Adolescent; Adult; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Turkey | 2004 |
Lack of genetic dispositions to hyperhomocysteinemia in Alzheimer disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Age Factors; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Chi-Square Distribution; Cystathionine beta-Synthase; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Genetic; Sex Factors; Survival Analysis | 2004 |
Hyperhomocysteinemia and deep vein thrombosis in orthotopic heart transplantation: a case report.
Topics: Adult; Anticoagulants; Enoxaparin; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Treatment Outcome; Venous Thrombosis | 2004 |
Don't forget about hydrogen sulphide.
Topics: Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Thrombosis | 2004 |
Abnormal lipid metabolism in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia.
Topics: Animals; Apolipoprotein B-100; Apolipoproteins B; Blotting, Northern; Cholesterol; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Disease Models, Animal; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Gene Expression Regulation; Genotype; Heterozygote; Homocysteine; Homozygote; Hyperhomocysteinemia; Lipid Metabolism; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Liver; Mice; Mice, Transgenic; Oxygen; Phosphatidylcholine-Sterol O-Acyltransferase; Risk Factors; RNA, Messenger; Sulfhydryl Compounds; Time Factors; Tissue Distribution; Triglycerides | 2004 |
Hyperhomocysteinemia, enzyme polymorphism and thiobarbituric Acid reactive system in children with high coronary risk family history.
Topics: Adolescent; Carbon-Nitrogen Ligases; Case-Control Studies; Child; Child, Preschool; Coronary Disease; Female; Fluorometry; Genetic Markers; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Polymorphism, Restriction Fragment Length; Risk Factors; Thiobarbituric Acid Reactive Substances | 2004 |
Homocysteine in uraemia--a puzzling and conflicting story.
Topics: Biomarkers; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Male; Prevalence; Prognosis; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Uremia | 2005 |
Mild hyperhomocysteinemia promotes renal hemodynamic dysfunction without histopathologic changes in adult rats.
Topics: Animals; Glomerular Filtration Rate; Hemodynamics; Homocysteine; Hyperhomocysteinemia; Kidney; Male; Rats; Rats, Wistar; Renal Circulation; Time Factors | 2004 |
Relationship between homocysteine and insulin resistance in women with polycystic ovary syndrome.
Topics: Adolescent; Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Polycystic Ovary Syndrome; Predictive Value of Tests | 2004 |
Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Arterial Occlusive Diseases; Chronic Disease; Endothelium, Vascular; Enzyme Inhibitors; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitric Oxide Synthase; Peripheral Vascular Diseases; Radial Artery; Ultrasonography; Vasodilation | 2004 |
C677T methylene-tetrahydrofolate reductase mutation in type 2 diabetic patients with and without hyperhomocysteinaemia.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Reference Values | 2004 |
Changes of homocysteine levels and arterial endothelial function in patients with high risk of coronary artery disease after 6-month folic acid supplementation.
Topics: Aged; Arteries; Chromatography, High Pressure Liquid; Coronary Artery Disease; Dietary Supplements; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Time; Treatment Outcome; Vitamin B 12 | 2004 |
[Recurrent spontaneous miscarriages and hyperhomocysteinemia].
Topics: Abortion, Habitual; Adult; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Pregnancy; Pregnancy Trimester, First | 2004 |
Enhanced cellular adenosine uptake limits adenosine receptor stimulation in patients with hyperhomocysteinemia.
Topics: Adenosine; Adult; Cystathionine beta-Synthase; Erythrocytes; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Microdialysis; Plethysmography; Receptors, Purinergic P1 | 2005 |
Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency.
Topics: Cystathionine; Cystatin C; Cystatins; Female; Folic Acid; HELLP Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Methylmalonic Acid; Oxidative Stress; Placental Insufficiency; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Uric Acid; Vitamin B 12; Vitamin B 6 | 2004 |
Fasting plasma total homocysteine levels and mortality and allograft loss in kidney transplant recipients: a prospective study.
Topics: Adult; Fasting; Female; Follow-Up Studies; Graft Survival; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Survival Analysis; Transplantation, Homologous | 2005 |
Hyperhomocysteinaemia is associated with uveitis but not with deep venous thrombosis in Behcet's disease.
Topics: Adolescent; Adult; Aged; Behcet Syndrome; Cohort Studies; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Tunisia; Uveitis; Venous Thrombosis | 2004 |
The risk of folate and vitamin B(12) deficiencies associated with hyperhomocysteinemia among pregnant women.
Topics: Adolescent; Adult; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Korea; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Effects of intravenous betaine on methionine-loading-induced plasma homocysteine elevation in rats.
Topics: Animals; Betaine; Disease Models, Animal; Glycine; Homocysteine; Hyperhomocysteinemia; Injections, Intravenous; Male; Methionine; Rats; Sarcosine | 2004 |
Protective role of mast cells in homocysteine-induced cardiac remodeling.
Topics: Animals; Diastole; Fibrosis; Heart Diseases; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Mast Cells; Myocardium; Rats; Rats, Mutant Strains; Ventricular Remodeling | 2005 |
Effect of folic acid on methionine and homocysteine metabolism in end-stage renal disease.
Topics: Administration, Oral; Adult; Aged; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kinetics; Male; Methionine; Methylation; Middle Aged; Renal Dialysis | 2005 |
Relationship between plasma homocysteine concentration and urinary markers of tubulointerstitial injury.
Topics: Adult; Albuminuria; Alpha-Globulins; Biomarkers; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Tubules; Male; Middle Aged | 2005 |
Genetic polymorphisms predisposing to hyperhomocysteinemia in cardiac transplant patients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Base Sequence; DNA Primers; Ferredoxin-NADP Reductase; Genetic Predisposition to Disease; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Retrospective Studies; Thromboembolism | 2005 |
The COMT inhibitor, entacapone, reduces levodopa-induced elevations in plasma homocysteine in healthy adult rats.
Topics: Animals; Antiparkinson Agents; Catechol O-Methyltransferase Inhibitors; Catechols; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Homocysteine; Hyperhomocysteinemia; Levodopa; Male; Nitriles; Rats; Rats, Wistar | 2005 |
No evidence for oxidative stress as a mechanism of action of hyperhomocysteinemia in humans.
Topics: Aged; Aged, 80 and over; Antioxidants; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Sex Characteristics; Solubility | 2004 |
Cystathionine beta synthase deficiency affects mouse endochondral ossification.
Topics: Animals; Bone and Bones; Breeding; Cystathionine beta-Synthase; Disease Models, Animal; DNA; Female; Genotype; Homocysteine; Hyperhomocysteinemia; Male; Marfan Syndrome; Mice; Mice, Inbred Strains; Mice, Knockout; Osteogenesis; Radiography; Scoliosis | 2005 |
Folate deficiency increases postischemic brain injury.
Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Colorimetry; DNA Damage; Folic Acid; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Infarction, Middle Cerebral Artery; Mice; Mice, Transgenic; Oxygen; Reperfusion; Reperfusion Injury; Risk; Stroke; Time Factors; Uracil-DNA Glycosidase | 2005 |
Inverse correlation between phenylacetate hydrolase activity of the serum PON1 protein and homocysteinemia in humans.
Topics: Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Homocysteine; Humans; Hyperhomocysteinemia; Phenylacetates | 2005 |
No evidence for hyperhomocysteinemia or increased prevalence of genetic polymorphisms in the homocysteine pathway in patients with moderate juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; DNA; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Polymorphism, Restriction Fragment Length | 2005 |
Hyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factors.
Topics: Acyl Coenzyme A; Animals; Cholesterol; Homocysteine; Hyperhomocysteinemia; Lipid Metabolism; Liver; Male; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factors | 2005 |
Influence of serum folic acid levels on plasma homocysteine concentrations in patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Methotrexate; Middle Aged; Statistics, Nonparametric; Vitamin B 12; Vitamin B Complex | 2006 |
Beneficial effects of Bifidobacteria in a gastroresistant seamless capsule on hyperhomocysteinemia in hemodialysis patients.
Topics: Bifidobacterium; Capsules; Colony Count, Microbial; Escherichia coli; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Indican; Intestines; Probiotics; Renal Dialysis; Uremia | 2005 |
Homocysteine and retinal vein occlusion: a population-based study.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Retinal Vein Occlusion; Risk Factors | 2005 |
Homocysteine and its nutritional determinants in two ethnic groups of Slovakia.
Topics: Adult; Biomarkers; Case-Control Studies; Feeding Behavior; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Middle Aged; Nutrition Surveys; Slovakia; Vitamin B 12; Vitamin B 6 | 2004 |
Prevalences of hyperhomocysteinemia, unfavorable cholesterol profile and hypertension in European populations.
Topics: Adult; Age Factors; Blood Pressure; Cardiovascular Diseases; Cholesterol; Cross-Sectional Studies; Europe; Female; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Prevalence; Risk Factors; Sex Factors | 2005 |
Distribution of 5,10-methylenetetrahydrofolate reductase (C667T) polymorphism and its association with red blood cell 5-methyltetrahydrofolate in the healthy Iranians.
Topics: Analysis of Variance; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Requirements; Polymorphism, Genetic; Tetrahydrofolates; Vitamin B 12 | 2005 |
Hyperhomocysteinemia and MTHFR C677T and A1298C polymorphisms are associated with chronic allograft nephropathy in renal transplant recipients.
Topics: Cross-Sectional Studies; DNA; Gene Frequency; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Postoperative Complications; Retrospective Studies; Risk Factors; Treatment Failure | 2004 |
Endothelial cell oxidative stress and signal transduction.
Topics: Arteriosclerosis; Endothelial Cells; Gene Expression; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, LDL; Mitogen-Activated Protein Kinases; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Umbilical Veins | 2000 |
Stroke and recurrent pregnancy loss due to hyperhomocysteinaemia.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Abortion, Habitual; Brain; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Infarction, Middle Cerebral Artery; Middle Aged; Mutation; Platelet Aggregation Inhibitors; Pregnancy; Stroke; Treatment Outcome; Vitamin B 12 | 2005 |
Serum homocysteine concentration in patients with acute MI and chronic IHD.
Topics: Acute Disease; Adult; Analysis of Variance; Bangladesh; Case-Control Studies; Chronic Disease; History, 18th Century; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia | 2005 |
Severe hyperhomocysteinaemia and 5-oxoprolinuria secondary to antiproliferative and antimicrobial drug treatment.
Topics: Acidosis; Anions; Anti-Infective Agents; Antineoplastic Agents; Child; Female; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Lymphoma, T-Cell; Phenytoin; Polymorphism, Genetic; Pyrrolidonecarboxylic Acid; Time Factors | 2005 |
Elevated plasma homocysteine levels in gestational diabetes mellitus.
Topics: Adult; Body Mass Index; Diabetes, Gestational; Female; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Age; Pregnancy | 2005 |
Homocysteine and the kidney.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Renal Insufficiency | 2005 |
Hyper-homocysteinemia is not a main feature of juvenile uncomplicated type 1 diabetes.
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male | 2005 |
Are plasma total homocysteine and other amino acids associated with glucose intolerance in uncomplicated pregnancies and preeclampsia?
Topics: Adult; Alanine; Amino Acids; Diabetes, Gestational; Female; Glucose Intolerance; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Prospective Studies; Vitamin B Complex | 2005 |
Folic acid supplementation can reduce the endothelial damage in rat brain microvasculature due to hyperhomocysteinemia.
Topics: Animals; Cerebrovascular Circulation; Dietary Supplements; Disease Models, Animal; Endothelium, Vascular; Energy Intake; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Reference Values; Thiobarbituric Acid Reactive Substances; Vitamin B 12; Weight Gain | 2005 |
Physiological variation in plasma total homocysteine concentrations in rats.
Topics: Aging; Animals; Biomarkers; Circadian Rhythm; Disease Models, Animal; Estrous Cycle; Female; Genital Diseases, Female; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar | 2005 |
[Relationship between plasma homocysteine and chronic complications in type 2 diabetes mellitus].
Topics: Adult; Aged; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2005 |
Plasma vitamin B12, folate and homocysteine levels in gastrectomized men.
Topics: Case-Control Studies; Folic Acid; Gastrectomy; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Male; Middle Aged; Peptic Ulcer; Risk Factors; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Hyperhomocysteinemia: cause or effect of disease?
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Vascular Diseases | 2005 |
Hyperhomocysteinemia in L-dopa treated Parkinson's disease patients: effect of cobalamin and folate administration.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Vitamin B 12 | 2005 |
Hyperhomocysteinemia, methylenetetrahydrofolate reductase 677TT genotype, and the risk for schizophrenia: a Dutch population based case-control study.
Topics: Adult; Case-Control Studies; Female; Gene Frequency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Netherlands; Polymorphism, Genetic; Risk Factors; Schizophrenia | 2005 |
Plasma homocysteine levels and the left ventricular systolic function in coronary artery disease patients.
Topics: Aged; Cholesterol, HDL; Coronary Artery Disease; Diabetes Mellitus, Type 1; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Multivariate Analysis; Racial Groups; Severity of Illness Index; Stroke Volume; Systole; Ventricular Dysfunction, Left | 2005 |
Prevalence of myocardial infarction is related to hyperhomocysteinemia but not influenced by C677T methylenetetrahydrofolate reductase and A2756G methionine synthase polymorphisms in diabetic and non-diabetic subjects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Polymorphism, Single Nucleotide; Regression Analysis | 2005 |
[Early arterial atherosclerosis and level of plasma homocysteine in simply obese children].
Topics: Adolescent; Atherosclerosis; Carotid Artery Diseases; Child; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Obesity; Tunica Intima; Tunica Media | 2005 |
[A clinical study of hyperhomocysteinemia in rheumatological diseases].
Topics: Adolescent; Adult; Child; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Rheumatic Diseases; Vitamin B 12 | 2005 |
[Effect of hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C --> T mutation in venous thromboembolism risk of young adults].
Topics: Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Risk Factors; Thromboembolism | 2005 |
[Homocysteine and low dietary intake: two complementary forms of impairment (correction of improvement)].
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thromboembolism; Vitamin B 12; Vitamin B 6 | 2005 |
Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment.
Topics: Adult; Anticoagulants; Betaine; Cognition Disorders; Confusion; Disease Progression; Drug Therapy, Combination; Folic Acid; Frontal Lobe; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Remission Induction; Seizures; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample.
Topics: Aged; Antioxidants; Australia; Brain; Case-Control Studies; Causality; Creatinine; Cross-Sectional Studies; Depressive Disorder; Depressive Disorder, Major; Female; Folic Acid; Folic Acid Deficiency; Health Status Indicators; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Personality Assessment; Predictive Value of Tests; Psychometrics; Reference Values; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Elevated plasma homocysteine level in slow coronary flow.
Topics: Case-Control Studies; Coronary Circulation; Coronary Vessels; Endothelium; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vasodilation | 2005 |
Polymorphisms of genes involved in homocysteine metabolism in preeclampsia and in uncomplicated pregnancies.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Case-Control Studies; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Vitamin B 12 | 2005 |
Cardiovascular and thrombophilic risk factors for idiopathic sudden sensorineural hearing loss.
Topics: Adult; Aged; Antibodies, Anticardiolipin; Antithrombins; Case-Control Studies; Factor V; Female; Hearing Loss, Sensorineural; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Lipoprotein(a); Lupus Coagulation Inhibitor; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Plasminogen Activator Inhibitor 1; Protein C; Protein S; Risk Factors; Thrombophilia; Time Factors | 2005 |
Elimination of high amounts of extracellular homocysteine in human cell lines.
Topics: Adenosine; Antioxidants; Arteriosclerosis; Carcinoma, Hepatocellular; Cell Line, Tumor; HeLa Cells; Homocysteine; Humans; Hyperhomocysteinemia; Thioctic Acid | 2005 |
von Willebrand factor multimer composition is modified following oral methionine load in women with thrombosis, but not in healthy women.
Topics: Adult; Case-Control Studies; Dimerization; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Middle Aged; Peptide Fragments; Peptide Hydrolases; Thrombosis; von Willebrand Factor | 2005 |
Hyperhomocysteinemia: an additional risk factor in white coat hypertension.
Topics: Blood Pressure Monitoring, Ambulatory; Body Mass Index; Coronary Artery Disease; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Office Visits; Retinal Diseases; Risk Factors; Smoking | 2005 |
Reduced plasma homocysteine levels in levodopa/entacapone treated Parkinson patients.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cross-Sectional Studies; Drug Therapy, Combination; Enzyme Inhibitors; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Vitamin B 12 | 2005 |
Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study.
Topics: Aged; Brain; Disease Progression; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; New York; Risk Factors; Social Class; Stroke; Vitamin B 12 Deficiency | 2005 |
Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver.
Topics: Animals; Apoptosis; Collagen Type I; Cystathionine beta-Synthase; Disease Models, Animal; Fatty Liver; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Liver; Liver Cirrhosis; Mice; Mice, Mutant Strains; Oxidative Stress; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Correlation between maternal plasma homocysteine and zinc levels in preeclamptic women.
Topics: Adult; Copper; Female; Homocysteine; Humans; Hyperhomocysteinemia; Labor Stage, First; Pre-Eclampsia; Pregnancy; Zinc | 2005 |
[The relationship between carotid artery atherosclerosis and hyperhomocysteinaemia].
Topics: Adult; Aged; Aged, 80 and over; Carotid Artery Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2005 |
Acute homocysteine administration does not elevate sympathetic nerve activity in rats.
Topics: Animals; Blood Pressure; Disease Models, Animal; Heart Rate; Homocysteine; Hyperhomocysteinemia; Infusions, Intravenous; Lumbosacral Plexus; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 2006 |
Reduction of butyrylcholinesterase activity in rat serum subjected to hyperhomocysteinemia.
Topics: Animals; Antioxidants; Arteriosclerosis; Ascorbic Acid; Butyrylcholinesterase; Disease Models, Animal; Down-Regulation; Enzyme Activation; Free Radicals; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Lipid Metabolism; Oxidative Stress; Rats; Rats, Wistar; Vitamin E | 2005 |
Folate and cobalamin deficiencies and hyperhomocysteinemia in Bangladesh.
Topics: Adult; Aged; Areca; Bangladesh; Cohort Studies; Creatinine; Diagnosis, Differential; Diet, Vegetarian; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Prospective Studies; Sex Factors; Smoking; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
[Folic acid in hyperhomocysteinemia?].
Topics: Contraindications; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Long-Term Care; Risk Factors; Spinal Diseases; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Prevalence of hyperhomocysteinaemia, activated protein C resistance and prothrombin gene mutation in inflammatory bowel disease.
Topics: Activated Protein C Resistance; Adult; Colitis, Ulcerative; Crohn Disease; Factor V; Factor VIII; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Middle Aged; Mutation; Protein C; Prothrombin; Vitamin B 12 | 2005 |
Family history, plasma homocysteine, and age at onset of symptoms of myocardial ischemia in patients with different methylenetetrahydrofolate reductase genotypes.
Topics: Age of Onset; Aged; DNA; Electrophoresis, Agar Gel; Female; Genetic Markers; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Israel; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Myocardial Ischemia; Pedigree; Polymerase Chain Reaction; Regression Analysis; Risk Factors; Smoking | 2005 |
Prevalence of hyperhomocysteinemia in adult gluten-sensitive enteropathy at diagnosis: role of B12, folate, and genetics.
Topics: Adult; Biomarkers; Celiac Disease; Chromatography, High Pressure Liquid; DNA; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Prevalence; Prospective Studies; Radioimmunoassay; Risk Factors; Vitamin B 12 | 2005 |
Alcoholism-associated hyperhomocysteinemia and previous withdrawal seizures.
Topics: Adult; Aged; Alcohol Withdrawal Seizures; Alcoholism; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Longitudinal Studies; Male; Middle Aged | 2005 |
Homocysteine concentrations and vascular complications in patients with type 2 diabetes.
Topics: Age of Onset; Aged; Biomarkers; Blood Pressure; Body Mass Index; Body Size; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Reference Values; Risk Factors | 2005 |
Hyperhomocysteinaemia as a risk factor for deep-vein thrombosis.
Topics: Adult; Aged; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Risk Factors; Venous Thrombosis | 2005 |
Protein-leaking membranes for hemodialysis: a new class of membranes in search of an application?
Topics: Albumins; Anemia; Clinical Trials as Topic; Dialysis Solutions; Glycosylation; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Kidney Failure, Chronic; Membranes, Artificial; Molecular Weight; Oxygen; Proteins; Renal Dialysis; Time Factors | 2005 |
Prevalence and mechanisms of hyperhomocysteinemia in chronic alcoholics.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcoholism; Avitaminosis; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methionine; Methylation; Middle Aged; Prevalence | 2005 |
Hyperhomocysteinaemia and aortic calcification are associated with fractures in patients on haemodialysis.
Topics: Aged; Calcinosis; Cross-Sectional Studies; Female; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Spinal Fractures; Vascular Diseases | 2005 |
Alcohol-associated severe hyperhomocysteinaemia.
Topics: Adult; Aged; Alcohol Drinking; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2005 |
[Plasma homocysteine concentration and its relationship with the development of preeclampsia. Effect of prenatal administration of folic acid].
Topics: Adolescent; Adult; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Poverty; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimesters; Socioeconomic Factors | 2005 |
Elevated level of plasma homocysteine in patients with slow coronary flow.
Topics: Adult; Blood Flow Velocity; Case-Control Studies; Coronary Circulation; Endothelium, Vascular; Female; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Turkey | 2005 |
[Is mild hyperhomocysteinemia an additional risk factor of the metabolic syndrome?].
Topics: Adult; Blood Glucose; Blood Pressure; Cholesterol; Cross-Sectional Studies; France; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Male; Metabolic Syndrome; Middle Aged; Risk Factors; Triglycerides | 2005 |
Endothelial function markers in parkinsonian patients with hyperhomocysteinemia.
Topics: Aged; Analysis of Variance; Antiparkinson Agents; Biomarkers; Case-Control Studies; E-Selectin; Endothelium, Vascular; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Levodopa; Male; Middle Aged; Nitric Oxide; Parkinson Disease; Superoxide Dismutase | 2005 |
Further evidence that hyperhomocysteinemia and methylenetetrahydrofolate reductase C677T and A1289C polymorphisms are not risk factors for schizophrenia.
Topics: Adult; Aged; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Retrospective Studies; Risk Factors; Schizophrenia; Sex Factors | 2005 |
Cavernosal dysfunction in a rabbit model of hyperhomocysteinaemia.
Topics: Animals; Cyclic GMP; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Impotence, Vasculogenic; Male; Muscle, Smooth, Vascular; Nitric Oxide; Organ Culture Techniques; Penis; Rabbits; Risk Factors; Superoxides; Veins | 2005 |
Aspirin downregulates homocysteine formation in stimulated human peripheral blood mononuclear cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Concanavalin A; Down-Regulation; Flow Cytometry; Homocysteine; Humans; Hyperhomocysteinemia; Leukocytes, Mononuclear; Lymphocyte Activation; Neopterin; Phytohemagglutinins; Pokeweed Mitogens; U937 Cells | 2005 |
Association between hyperhomocysteinemia and ultrasonographic atherosclerotic indices of carotid arteries in chronic hemodialysis patients.
Topics: Adult; Aged; Atherosclerosis; Carotid Arteries; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Renal Dialysis; Time Factors; Ultrasonography, Doppler | 2005 |
Hyperhomocysteinaemia induced by dietary folate restriction causes kidney oxidative stress in rats.
Topics: Animals; Antioxidants; Chemokine CCL2; Folic Acid; Free Radical Scavengers; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Kidney; Lipid Peroxidation; Male; Oxidative Stress; Proteins; Rats; Rats, Wistar; Receptors, LDL; Superoxide Dismutase; Vitamin B Deficiency; Weight Loss | 2005 |
Correlation of plasma homocysteine level with arterial stiffness and pulse pressure in hemodialysis patients.
Topics: Adult; Aged; Atherosclerosis; Blood Pressure; Brachial Artery; Female; Ferritins; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors | 2005 |
Embryonic cerebellar granule cells are resistant to necrosis induced by homocysteine.
Topics: Aging; Animals; Animals, Newborn; Cells, Cultured; Disease Susceptibility; Homocysteine; Hyperhomocysteinemia; Mice; Microscopy, Electron, Transmission; Necrosis; Neurodegenerative Diseases; Neurons | 2005 |
The association between hyperhomocysteinemia and ischemic stroke in patients with non-valvular atrial fibrillation.
Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Stroke | 2005 |
Hyperhomocysteinemia and cognitive function: more than just a casual link?
Topics: Aging; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2005 |
Are we losing homocysteine as a cardiovascular risk factor?
Topics: Atherosclerosis; Biomarkers; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Assessment; Risk Factors | 2005 |
Young man presenting with chest pain.
Topics: Adrenergic beta-Antagonists; Adult; Chest Pain; Coronary Angiography; Diagnosis, Differential; Electroencephalography; Homocysteine; Humans; Hyperhomocysteinemia; Male | 2005 |
Plasma homocysteine levels in patients with isolated coronary artery ectasia.
Topics: Biomarkers; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Dilatation, Pathologic; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Vitamin B 12 | 2005 |
Ascorbate is particularly effective against LDL oxidation in the presence of iron(III) and homocysteine/cystine at acidic pH.
Topics: Ascorbic Acid; Catalysis; Cystine; Dehydroascorbic Acid; Ferric Compounds; Histidine; Homocysteine; Humans; Hydrogen-Ion Concentration; Hyperhomocysteinemia; Lipoproteins, LDL; Oxidation-Reduction; Sulfhydryl Compounds | 2005 |
Association of B vitamins status and homocysteine levels in elderly Taiwanese.
Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutrition Surveys; Nutritional Status; Sex Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 2005 |
Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans.
Topics: Adult; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Diet, Vegetarian; Female; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Triglycerides; Vegetables; Vitamin B 12 | 2005 |
[Folate reduces monocyte chemoattractant protein-1 expression in rats with hyperhomocysteinemia].
Topics: Animals; Aorta; Chemokine CCL2; Endothelium, Vascular; Folic Acid; Homocysteine; Hyperhomocysteinemia; Leukocytes, Mononuclear; Male; Methionine; Random Allocation; Rats; Rats, Sprague-Dawley | 2005 |
Melatonin prevents hyperhomocysteinemia and neural lipid peroxidation induced by methionine intake.
Topics: Animals; Antioxidants; Brain; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Methionine; Oxidative Stress; Rats; Rats, Wistar | 2005 |
Methylenetetrahydrofolate reductase 677 C-T and homocysteine levels in Turkish patients with pseudoexfoliation.
Topics: Aged; DNA Mutational Analysis; Exfoliation Syndrome; Female; Genotype; Glaucoma; Homocysteine; Humans; Hyperhomocysteinemia; Intraocular Pressure; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Prospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Turkey | 2005 |
What is homocysteine and why is it important in terms of atherosclerosis?
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2005 |
Measuring the homocysteine level.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Hematologic Tests; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2005 |
From your physician assistant. Should I have a test for homocysteine?
Topics: Hematologic Tests; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2005 |
Elevated levels of homocysteine compromise blood-brain barrier integrity in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Cell Adhesion; Cystathionine beta-Synthase; Diet; Evans Blue; Heterozygote; Homocysteine; Hyperhomocysteinemia; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Up-Regulation | 2006 |
Asymmetric dimethylarginine, homocysteine and renal function--is there a relation?
Topics: Adult; Age Factors; Arginine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Function Tests; Male; Middle Aged; Renal Dialysis | 2005 |
Young hemodialysis patients are exposed to hyperhomocysteinemia.
Topics: Adult; Alcohol Drinking; Cardiovascular Diseases; Cross-Sectional Studies; Electrocardiography; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Ischemia; Prognosis; Prospective Studies; Renal Dialysis; Risk Factors | 2005 |
[Hyperhomocysteinemia as a risk factor for coronary atherosclerotic diseases in the elderly].
Topics: Aged; Aged, 80 and over; Brazil; Coronary Angiography; Coronary Artery Disease; Epidemiologic Methods; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Smoking | 2005 |
Thrombophilias and stroke: diagnosis, treatment, and prognosis.
Topics: Anticoagulants; Cystathionine beta-Synthase; Factor V; Genetic Predisposition to Disease; Genetic Testing; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Methylenetetrahydrofolate Reductase (NADPH2); Platelet Activation; Platelet Aggregation; Polymorphism, Genetic; Prognosis; Protein S Deficiency; Prothrombin; Secondary Prevention; Stroke; Thrombophilia; Warfarin | 2005 |
Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Biopterins; Cells, Cultured; Cystathionine beta-Synthase; Endothelium, Vascular; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Kinase C; Pterins; Superoxide Dismutase; Vasodilation | 2005 |
Do low doses of folic acid result in maximum lowering of homocysteine?
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 6 | 2005 |
Smoking, homocysteine and degree of arteriolar retinopathy.
Topics: Adult; Arterioles; China; Cross-Sectional Studies; Disease Progression; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Odds Ratio; Ophthalmoscopy; Prevalence; Retinal Diseases; Retinal Vessels; Risk Factors; Sampling Studies; Severity of Illness Index; Smoking | 2005 |
Chemokine RANTES is upregulated in monocytes from patients with hyperhomocysteinemia.
Topics: Adult; Chemokine CCL5; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipopolysaccharides; Male; Middle Aged; Monocytes; RNA, Messenger | 2005 |
Hyperhomocysteinemia inhibits post-injury reendothelialization in mice.
Topics: Animals; Carotid Artery Injuries; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Cystathionine beta-Synthase; Endothelial Cells; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Regeneration; Stem Cells; Tunica Intima; Umbilical Veins; Wound Healing | 2006 |
Are homocysteine and MTHFR genotype polymorphism associated with arteriovenous fistula patency?
Topics: Arteriovenous Shunt, Surgical; Confounding Factors, Epidemiologic; Diet; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Riboflavin; Risk Factors; Thrombophilia; Thrombosis | 2005 |
Hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations in patients with inflammatory bowel disease.
Topics: Adult; Confidence Intervals; Data Interpretation, Statistical; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Prevalence; Sex Factors; Thromboembolism; Vitamin B 12 | 2005 |
Hyperhomocysteinemia is associated with volumetric white matter change in patients with small vessel disease.
Topics: Aged; Brain; Cerebrovascular Disorders; Cognition Disorders; Cohort Studies; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychometrics; Regression Analysis; Risk Factors; Stroke; Vitamin B 12 | 2006 |
Effects of homocysteine and ginsenoside Rb1 on endothelial proliferation and superoxide anion production.
Topics: Animals; Cell Division; Cell Line; Endothelial Cells; Ginsenosides; Homocysteine; Humans; Hyperhomocysteinemia; Lymph Nodes; Mice; Oxidative Stress; Superoxides; Umbilical Veins | 2006 |
Relationship between homocysteine and neopterin concentrations in patients with gynecological cancer.
Topics: Aged; Female; Genital Neoplasms, Female; Homocysteine; Humans; Hyperhomocysteinemia; Neopterin | 2006 |
RETRACTED: Homocysteine as a predictive factor for hip fracture in elderly women with Parkinson's disease.
Topics: Accidental Falls; Aged; Antiparkinson Agents; Cohort Studies; Female; Follow-Up Studies; Fractures, Spontaneous; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Immobilization; Incidence; Japan; Levodopa; Osteoporosis; Parkinson Disease; Proportional Hazards Models; Risk Factors | 2005 |
[Don't forget homocystéinemia's screening in young patients with arterial thrombosis].
Topics: Adult; Arterial Occlusive Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Thrombosis | 2006 |
Homocysteine and its effects on in-stent restenosis.
Topics: Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Models, Biological; Myocardial Infarction; Stents | 2005 |
Design and statistical issues in the homocysteinemia in kidney and end stage renal disease (HOST) study.
Topics: Adult; Cause of Death; Double-Blind Method; Folic Acid; Homocysteine; Hospitals, Veterans; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Middle Aged; Multicenter Studies as Topic; Patient Selection; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Renal Dialysis; Research Design; Treatment Outcome; Vitamin B 12 | 2004 |
[Hyperhomocysteine like thrombocytic risk factor in patient with systemic lupus erythematous with antiphospholipid syndrome].
Topics: Adult; Aged; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Argentina; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lupus Erythematosus, Systemic; Male; Middle Aged; Risk Factors; Thrombosis; Venous Thrombosis | 2005 |
B vitamins and homocysteine.
Topics: Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B 12; Vitamin B 6 | 2005 |
Retinal vein occlusion, homocysteine, and methylene tetrahydrofolate reductase genotype.
Topics: Aged; Case-Control Studies; DNA Mutational Analysis; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2005 |
Homocysteine levels are not associated with cardiovascular autonomic function in elderly Caucasian subjects without or with type 2 diabetes mellitus: the Hoorn Study.
Topics: Age Factors; Aged; Antihypertensive Agents; Autonomic Nervous System; Blood Pressure; Creatinine; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Metabolism Disorders; Glucose Tolerance Test; Heart Rate; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Male; Middle Aged; Sex Factors; Waist-Hip Ratio | 2005 |
Proceedings of the Fourth Conference on Hyperhomocysteinemia. Saarbrücken, Germany. April 14-16, 2005.
Topics: Animals; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2005 |
Homocysteine and coronary microcirculation: is it a microvasculopathic agent?
Topics: Administration, Oral; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Coronary Circulation; Coronary Disease; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Methionine | 2006 |
Combining 2nd-trimester maternal serum homocysteine levels and uterine artery Doppler for prediction of preeclampsia and isolated intrauterine growth restriction.
Topics: Abruptio Placentae; Adult; Arteries; Biomarkers; Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Mass Screening; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Second; Prospective Studies; Sensitivity and Specificity; Stillbirth; Ultrasonography, Doppler; Uterus | 2006 |
Elevated plasma homocysteine levels in patients with isolated coronary artery ectasia.
Topics: Biomarkers; Coronary Angiography; Coronary Disease; Dilatation, Pathologic; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Retrospective Studies; Risk Factors | 2006 |
Erythrocyte membrane acetylcholinesterase activity in subjects with MTHFR 677C-->T genotype.
Topics: Acetylcholinesterase; Adult; Alanine; Cytidine; Erythrocyte Membrane; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Dehydrogenase (NADP); Phenylalanine | 2006 |
Plasma reduced homocysteine and other aminothiol concentrations in patients with CKD.
Topics: Adult; Aged; Atherosclerosis; Biomarkers; C-Reactive Protein; Chronic Disease; Cysteine; Dipeptides; Female; Folic Acid; Glutathione; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Oxidation-Reduction; Peritoneal Dialysis; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Vitamin B 12 | 2006 |
Plasma hyperhomocysteinemia, MTHFR polymorphism and thromboembolic disease: an example of gene-nutrition interactions in chronic disease.
Topics: Chronic Disease; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Thromboembolism; Vitamin B 12; Vitamin B 6 | 2005 |
[The relationship between the plasma homocysteine level and the polymorphism of MTHFR gene C667T in liver cirrhosis].
Topics: Female; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Point Mutation; Polymorphism, Genetic | 2005 |
Factors involved in baseline hyperhomocysteinemia in renal transplantation.
Topics: Adult; Aged; C-Reactive Protein; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prospective Studies; Reference Values; Vitamin B 12 | 2005 |
Moderate hyperhomocysteinemia and early-onset central retinal vein occlusion.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxal Phosphate; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2006 |
Increased plasma protein homocysteinylation in hemodialysis patients.
Topics: Adult; Aged; Blood Proteins; Cardiovascular Diseases; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Male; Middle Aged; Models, Molecular; Protein Binding; Protein Processing, Post-Translational; Renal Dialysis; Serum Albumin; Uremia; Vitamin B 12; Vitamin B 6; Xenobiotics | 2006 |
Homocysteine: call off the funeral.
Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Stroke; Vitamin B 12 | 2006 |
Homocysteine and risk in end-stage renal disease: a matter of context.
Topics: Blood Pressure; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Kidney Failure, Chronic; Malnutrition; Risk Factors | 2006 |
Impact of malnutrition-inflammation on the association between homocysteine and mortality.
Topics: Aged; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Male; Malnutrition; Middle Aged; Prospective Studies; Renal Dialysis; Risk Factors | 2006 |
[Hyperhomocysteinemia as a vascular risk factor in chronic hemodialysis patients].
Topics: Atherosclerosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylenetetrahydrofolate Reductase (NADPH2); Renal Dialysis; Risk Factors; Thrombosis; Vitamin B 12; Vitamin B Complex | 2005 |
Methionine adenosyltransferase (MAT) I/III deficiency with concurrent hyperhomocysteinaemia: two novel cases.
Topics: Adult; Child, Preschool; Diagnosis, Differential; Female; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Mutation; Mutation, Missense | 2005 |
Mild hyperhomocysteinaemia is associated with increased aortic stiffness in general population.
Topics: Adult; Aged; Aortic Diseases; Biomarkers; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Population Surveillance; Pulsatile Flow; Retrospective Studies; Risk Factors; Ultrasonography; Vascular Resistance | 2006 |
Folic acid pretreatment prevents the reduction of Na(+),K(+)-ATPase and butyrylcholinesterase activities in rats subjected to acute hyperhomocysteinemia.
Topics: Animals; Butyrylcholinesterase; Cerebral Cortex; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances; Vitamin B Complex | 2006 |
Homocysteine and its determinants in nondialyzed chronic kidney disease patients.
Topics: Anthropometry; Case-Control Studies; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Function Tests; Linear Models; Male; Middle Aged; Nutrition Assessment; Nutritional Status; Prevalence; Vitamin B 12 | 2006 |
Involvement of Rho-kinase in experimental vascular endothelial dysfunction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Antibiotics, Antineoplastic; Aorta, Thoracic; Atorvastatin; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Endothelium, Vascular; Heptanoic Acids; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Intracellular Signaling Peptides and Proteins; Male; Nitrates; Nitrites; Oxidative Stress; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrroles; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Streptozocin; Thiobarbituric Acid Reactive Substances; Vasodilation | 2006 |
Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit.
Topics: Acetophenones; Acetylcholine; Administration, Oral; Animals; Aorta; Blotting, Western; Cyclic GMP; Dietary Supplements; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Methionine; NADPH Oxidases; Nitric Oxide Donors; Nitroprusside; Onium Compounds; Penicillamine; Rabbits; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2006 |
Total plasma homocysteine, folate, and vitamin B12 status in healthy Iranian adults: the Tehran homocysteine survey (2003-2004)/a cross-sectional population based study.
Topics: Adult; Age Factors; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Iran; Male; Middle Aged; Nutrition Surveys; Prevalence; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Homocysteine-lowering action is another potential cardiovascular protective factor of aged garlic extract.
Topics: Animals; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Garlic; Homocysteine; Hyperhomocysteinemia; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley | 2006 |
Influence of methionine synthase (A2756G) and methionine synthase reductase (A66G) polymorphisms on plasma homocysteine levels and relation to risk of coronary artery disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Analysis of Variance; Case-Control Studies; Coronary Artery Disease; Female; Ferredoxin-NADP Reductase; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Mutation; Polymorphism, Genetic; Risk Factors; Statistics, Nonparametric | 2006 |
Low-grade systemic inflammation profile, unrelated to homocysteinemia, in obese children.
Topics: Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Child; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Male; Obesity; Risk Factors; Serum Amyloid A Protein | 2005 |
Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia.
Topics: Amino Acid Sequence; Blood Coagulation; Dose-Response Relationship, Drug; Fibrin; Fibrinogen; Fibrinolysis; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Models, Biological; Molecular Sequence Data; Plasminogen; Protein Binding; Radiation-Protective Agents; Structure-Activity Relationship; Thrombosis; Tissue Plasminogen Activator | 2006 |
Why is homocysteine elevated in renal failure and what can be expected from homocysteine-lowering?
Topics: Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Function Tests; Male; Prognosis; Renal Dialysis; Risk Assessment; Severity of Illness Index; Treatment Outcome; Vitamin B 6 | 2006 |
Homocysteine activates cAMP-response element binding protein in HepG2 through cAMP/PKA signaling pathway.
Topics: Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Hepatocytes; Homocysteine; Humans; Hydroxymethylglutaryl CoA Reductases; Hyperhomocysteinemia; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2006 |
No added value of the methionine loading task in assessment for venous thrombosis and cardiovascular disease risk.
Topics: Aged; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Practice Guidelines as Topic; Risk; ROC Curve; Venous Thrombosis | 2006 |
Influence of folate serum concentration on plasma homocysteine levels in HIV-positive patients exposed to protease inhibitors undergoing HAART.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cross-Sectional Studies; Female; Folic Acid; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Predictive Value of Tests; Protease Inhibitors; Risk Factors; Time Factors | 2006 |
Hyperhomocysteinemia in chronic renal failure patients: relation to tissue factor and platelet aggregation.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Platelet Aggregation; Renal Dialysis; Thromboplastin; Vitamin B 12; Vitamin B 6 | 2006 |
Mitochondrial mechanism of microvascular endothelial cells apoptosis in hyperhomocysteinemia.
Topics: Animals; Apoptosis; Caspases; Cells, Cultured; Cytochromes c; Endothelial Cells; Enzyme Activation; Gene Expression; Homocysteine; Hyperhomocysteinemia; Membrane Potentials; Microcirculation; Mitochondria; Mitochondrial Membranes; Rats; Reactive Oxygen Species; RNA, Small Interfering | 2006 |
Homocysteine targeting of plasma proteins in hemodialysis patients.
Topics: Blood Proteins; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Protein Processing, Post-Translational; Renal Dialysis | 2006 |
Homocysteine trials--clear outcomes for complex reasons.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Myocardial Infarction; Secondary Prevention; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
Hyperhomocysteinemia increases damage on brain slices exposed to in vitro model of oxygen and glucose deprivation: prevention by folic acid.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Folic Acid; Glucose; Homocysteine; Hyperhomocysteinemia; Hypoxia; Hypoxia-Ischemia, Brain; In Vitro Techniques; Lactate Dehydrogenases; Male; Rats; Rats, Wistar; Vitamin A; Vitamin B Complex | 2006 |
Hyperhomocysteinemia in patients with arterial occlusive disease.
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Risk Assessment; Risk Factors; Vitamin B 12 | 2006 |
Hyperhomocysteinemia and hypercoagulability in primary biliary cirrhosis.
Topics: Adult; Aged; Antithrombin III; Female; Folic Acid; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis, Biliary; Male; Middle Aged; Peptide Hydrolases; Platelet Function Tests; Thrombomodulin; Thrombophilia; Thromboplastin; Vitamin B 12; Vitamin B 6 | 2006 |
Plasma homocysteine affects fibrin clot permeability and resistance to lysis in human subjects.
Topics: Acute Disease; Adult; Aged; Blood Coagulation; Case-Control Studies; Coronary Artery Disease; Diabetes Mellitus; Drug Resistance; Fibrin; Fibrinolytic Agents; Folic Acid; Hematinics; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Male; Middle Aged; Permeability; Recombinant Proteins; Tissue Plasminogen Activator | 2006 |
Influence of PON1 polymorphisms on the association between serum paraoxonase 1 and homocysteinemia in a general population.
Topics: Adult; Aged; Aryldialkylphosphatase; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Polymorphism, Genetic | 2006 |
Thrombophilic risk factors and homocysteine levels in Behçet's disease in eastern Spain and their association with thrombotic events.
Topics: Adult; Behcet Syndrome; Case-Control Studies; Factor V; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Spain; Thrombophilia; Thrombosis | 2006 |
Homocysteine levels in amniotic fluid. Relationship with birth-weight.
Topics: Adult; Amniotic Fluid; Birth Weight; Chromosome Aberrations; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Infant, Small for Gestational Age; Male; Pregnancy; Pregnancy Outcome; Prenatal Diagnosis; Twins | 2006 |
PPAR-gamma agonists decrease hyperhomcysteinemia and cardiac dysfunction: new hope for ailing diabetic hearts?
Topics: Animals; Cardiotonic Agents; Diabetes Complications; Homocysteine; Hyperhomocysteinemia; Mice; PPAR gamma; Treatment Outcome; Ventricular Dysfunction, Left | 2006 |
Hyperhomocysteinemia predicts total and cardiovascular mortality in high-risk women.
Topics: Aged; Cardiovascular Diseases; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Postmenopause; Predictive Value of Tests; Prognosis; Prospective Studies; Risk Factors; Survival Rate; Time Factors; White People | 2006 |
Hyperhomocystinemia in patients with coronary artery disease.
Topics: Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Severity of Illness Index | 2006 |
[Effect of hyperhomocysteinemia on cardiac remodeling in rats].
Topics: Animals; Heart; Homocysteine; Hyperhomocysteinemia; Male; Myocardial Contraction; Rats; Rats, Wistar; Systole; Ventricular Remodeling | 2006 |
Kazakhstan: a folate-deficient area?
Topics: Adult; Aged; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Kazakhstan; Male; Middle Aged; Nutrition Assessment; Nutritional Status; Prevalence; Vegetables | 2006 |
Hyperhomocysteinemia associated with decreased renal transsulfuration activity in Dahl S rats.
Topics: Adenosylhomocysteinase; Animals; Chromatography, High Pressure Liquid; Chromosomes; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Enzymes; Homocysteine; Hyperhomocysteinemia; Kidney; Kidney Cortex; Kidney Tubules, Proximal; Male; Nephrons; Rats; Rats, Inbred BN; Rats, Inbred Dahl; RNA, Messenger; Sulfur; Tissue Distribution | 2006 |
Hyperhomocysteinemia can be ameliorated by dimethylsulfoniopropionate in place of folic acid in mice.
Topics: Animals; Betaine; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kinetics; Male; Mice; Mice, Inbred ICR; Sulfonium Compounds | 2006 |
Fuzzy role of hyperhomocysteinemia in hemodialysis patients' mortality.
Topics: Adult; Aged; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 2006 |
Role of MTHFR C677T polymorphism in ischemic stroke.
Topics: Adolescent; Adult; Brain Ischemia; Child; Child, Preschool; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Stroke | 2006 |
Effect of homocysteine lowering by 5-methyltetrahydrofolate on redox status in hyperhomocysteinemia.
Topics: Adult; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; DNA; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Sulfhydryl Compounds; Tetrahydrofolates; Vitamin B 12; Vitamin E | 2006 |
Mild hyperhomocysteinemia and the common C677T polymorphism of methylene tetrahydrofolate reductase gene are not associated with the metabolic syndrome in Type 2 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Linear Models; Male; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Obesity; Polymorphism, Genetic; Triglycerides; Vitamin B 12 | 2006 |
Rationale and design for the CARDIOVIT Study (Cardiovit, Atherosclerotic vascular disease and hypeRhomocysteinemia: an epiDemiological study in Indians, additionally evaluating the effect of Oral VITamin supplementation).
Topics: Adult; Antioxidants; Atherosclerosis; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Prevalence; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome; Vitamin B Complex; Vitamins | 2006 |
An assessment of the potential value of elevated homocysteine in predicting alcohol-withdrawal seizures.
Topics: Adult; Aged; Alcohol Withdrawal Seizures; Alcoholism; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pilot Projects; Predictive Value of Tests; Psychiatric Status Rating Scales; Risk Assessment; Risk Factors; ROC Curve; Sensitivity and Specificity | 2006 |
Inhibition of ceramide-redox signaling pathway blocks glomerular injury in hyperhomocysteinemic rats.
Topics: Acetophenones; Animals; Ceramides; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix; Fatty Acids, Monounsaturated; Homocysteine; Hyperhomocysteinemia; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Matrix Metalloproteinase 1; NADPH Oxidases; Oxidation-Reduction; rac GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1 | 2006 |
Total serum homocysteine, folate and vitamin B12 in a Greek school age population.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Age Factors; Aging; Blood Pressure; Cardiovascular Diseases; Child; Child Nutritional Physiological Phenomena; Female; Folic Acid; Greece; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Reference Values; Risk Factors; Sex Factors; Social Class; Vitamin B 12; Vitamin B Complex | 2006 |
Pathophysiological consequences of homocysteine excess.
Topics: Autoantibodies; Blood Proteins; Cell Death; Diet; Endoplasmic Reticulum; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Methionine; Protein Binding | 2006 |
Hyperhomocysteinaemia, methylenetetrahydrofolate reductase polymorphism and risk of coronary artery disease.
Topics: Arabs; Case-Control Studies; Cholesterol; Coronary Artery Disease; Creatinine; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Triglycerides; Tunisia | 2006 |
Novel genomic loci influencing plasma homocysteine levels.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Age Factors; Aged; Black or African American; Body Mass Index; Chromosome Mapping; Chromosomes, Human; Cohort Studies; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Estrogens; Female; Genotype; Guanidinoacetate N-Methyltransferase; Homocysteine; Humans; Hyperhomocysteinemia; Lod Score; Male; Middle Aged; Protein-Arginine N-Methyltransferases; Risk Factors; Sex Factors; United States; White People | 2006 |
Plasma homocysteine levels and vitamin B status in patients with Pseudoexfoliation syndrome.
Topics: Aged; Exfoliation Syndrome; Eye; Female; Folic Acid; Glaucoma; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retinal Vein Occlusion; Risk Factors; Turkey; Vitamin B 12; Vitamin B 6 | 2006 |
A study of plasma total homocysteine levels in healthy people.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Bulgaria; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reference Values; Statistics, Nonparametric | 2005 |
Preoperative folate and homocysteine status in patients undergoing major surgery.
Topics: Anesthetics, Inhalation; Dietary Supplements; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multivariate Analysis; Nitrous Oxide; Nutrition Assessment; Nutritional Status; Preoperative Care; Surveys and Questionnaires | 2006 |
Changes in atrium and thoracic aorta reactivity to adenosinergic and adrenergic agonists in experimental hyperhomocysteinemia.
Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Blood Pressure; Dipyridamole; Heart Atria; Heart Rate; Homocysteine; Hyperhomocysteinemia; Isoproterenol; Male; Methionine; Phenylephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline; Vasoconstriction; Vasodilation | 2006 |
Homocysteine measurements in geriatric patients.
Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Female; Folic Acid Deficiency; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Reference Values; Regression Analysis; Risk Factors; Vitamin B 12 Deficiency | 2006 |
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in patients with Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Reference Values; Vitamin B 12 | 2006 |
Hyperhomocysteinemia increases arterial permeability and stiffness in mice.
Topics: Animals; Arteries; Atherosclerosis; Capillary Permeability; Elasticity; Endothelium, Vascular; Homocysteine; Hyperhomocysteinemia; Lipoproteins; Methionine; Mice; Mice, Inbred C57BL; Nitric Oxide; Superoxides; Vascular Resistance | 2006 |
[Characteristics of hyperhomocysteinemia in dialysis patients].
Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Dyslipidemias; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors | 2006 |
Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation.
Topics: Acid Phosphatase; Animals; Bone Marrow Cells; Bone Resorption; Cell Differentiation; Cells, Cultured; Fractures, Bone; Homocysteine; Hyperhomocysteinemia; Isoenzymes; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Osteoclasts; Osteoporosis; Protein Kinases; Reactive Oxygen Species; Risk Factors; Tartrate-Resistant Acid Phosphatase | 2006 |
3-Deazaadenosine mitigates arterial remodeling and hypertension in hyperhomocysteinemic mice.
Topics: Animals; Antibiotics, Antineoplastic; Aorta; Blood Pressure; Connexin 43; Cystathionine beta-Synthase; Echocardiography; Endothelium, Vascular; Extracellular Matrix; Female; Heart Rate; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred Strains; Mice, Knockout; Muscle, Smooth, Vascular; Reverse Transcriptase Polymerase Chain Reaction; Tubercidin | 2006 |
Evaluation of total plasma homocysteine in Indian newborns using heel-prick samples.
Topics: Breast Feeding; Chromatography, Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; India; Infant, Newborn; Male | 2006 |
Polymorphism C776G in the transcobalamin II gene and homocysteine, folate and vitamin B12 concentrations. Association with MTHFR C677T and A1298C and MTRR A66G polymorphisms in healthy children.
Topics: Brazil; Child; Child, Preschool; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Polymorphism, Genetic; Reference Values; Risk Factors; Transcobalamins; Vitamin B 12 | 2007 |
Determinants of fasting total serum homocysteine levels in liver transplant recipients.
Topics: Adult; Aged; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Liver Transplantation; Male; Middle Aged; Risk Factors | 2006 |
MTHFR C677T and A1298C gene polymorphisms and hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Tunisia | 2007 |
Associations between serum insulin and homocysteine in a Swedish population-a potential link between the metabolic syndrome and hyperhomocysteinemia: the Skaraborg project.
Topics: Adult; Aged; Aged, 80 and over; Body Mass Index; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Kidney; Kidney Function Tests; Life Style; Male; Metabolic Syndrome; Middle Aged; Motor Activity; Sex Characteristics; Smoking; Surveys and Questionnaires; Sweden | 2006 |
Possible role of Akt to improve vascular endothelial dysfunction in diabetic and hyperhomocysteinemic rats.
Topics: Acetylcholine; Animals; Aorta; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Male; NADPH Oxidases; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Proto-Oncogene Proteins c-akt; Quinones; Rats; Rats, Wistar; RNA, Messenger; Superoxides; Thiobarbituric Acid Reactive Substances; Vasodilation | 2007 |
Homocysteine, folate and vitamin b12 in patients with coronary heart disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Chromatography, High Pressure Liquid; Coronary Disease; Creatinine; Diet; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Vitamin B 12; Vitamin B Complex | 2006 |
[Peculiarities of atherosclerotic injury of carotid arteries in patients with coronary artery disease with hyperhomocysteinemia].
Topics: Adult; Aged; Biomarkers; Carotid Arteries; Carotid Artery Diseases; Coronary Disease; Disease Progression; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Severity of Illness Index; Ultrasonography | 2006 |
Body composition: an important determinant of homocysteine and methionine concentrations in healthy individuals.
Topics: Adipose Tissue; Adult; Body Composition; Body Water; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Menopause; Methionine; Middle Aged; Muscle, Skeletal; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
G1793A polymorphisms in the methylene-tetrahydrofolate gene: effect of folic acid on homocysteine levels.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Folic Acid; Gene Frequency; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Vitamin B 12 | 2006 |
[The effect of lowering plasma homocysteine levels on some parameters of thrombotic activity in haemodialyzed patients with chronic renal failure].
Topics: Aged; Dose-Response Relationship, Drug; Female; Folic Acid; Hematologic Tests; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Reference Values; Renal Dialysis; Thrombosis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
Methylenetetrahydrofolate reductase 677 C-T and homocysteine levels in Turkish patients with pseudoexfoliation.
Topics: DNA Mutational Analysis; Exfoliation Syndrome; Genotype; Glaucoma; Homocysteine; Humans; Hyperhomocysteinemia; Intraocular Pressure; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Turkey | 2006 |
[Hyperhomocysteinemia in patients with atherosclerotic extracranial disease of the carotid artery].
Topics: Aged; Arteriosclerosis; C-Reactive Protein; Carotid Artery, Common; Carotid Stenosis; Creatinine; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors | 2006 |
Binding of copper is a mechanism of homocysteine toxicity leading to COX deficiency and apoptosis in primary neurons, PC12 and SHSY-5Y cells.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Cells, Cultured; Chelating Agents; Copper; Cytochrome-c Oxidase Deficiency; Dose-Response Relationship, Drug; Electron Transport Complex IV; Homocysteine; Humans; Hyperhomocysteinemia; Menkes Kinky Hair Syndrome; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; PC12 Cells; Rats | 2006 |
Homocysteine and retinal emboli: the Blue Mountains Eye Study.
Topics: Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Embolism; Female; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; New South Wales; Odds Ratio; Prevalence; Retinal Artery Occlusion; Retinal Vein Occlusion | 2006 |
Homocysteine-mediated activation and mitochondrial translocation of calpain regulates MMP-9 in MVEC.
Topics: Animals; Calcium-Binding Proteins; Calpain; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Coronary Vessels; Cytosol; Dipeptides; Endothelium, Vascular; Flavonoids; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Mitochondria; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Rats; Rats, Wistar; Uncoupling Agents | 2006 |
Association of aminothiols with the clinical outcome in hemodialysis patients: comparison of chromatography and immunoassay for homocysteine determination.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Cohort Studies; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Sulfhydryl Compounds | 2006 |
Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model.
Topics: Alanine Transaminase; Animals; Betaine; Biosynthetic Pathways; Central Nervous System Depressants; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Ethanol; Fatty Liver, Alcoholic; Heat-Shock Proteins; Homocysteine; Hyperhomocysteinemia; Lipogenesis; Lipotropic Agents; Liver; Mice; Mice, Knockout; Models, Animal; Molecular Chaperones; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Triglycerides | 2006 |
Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats.
Topics: Adenine; Animals; Cystathionine beta-Synthase; Diet; Dose-Response Relationship, Drug; Enzyme Activation; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2006 |
Nutritional determinants of plasma total homocysteine distribution in the Canary Islands.
Topics: Adolescent; Adult; Age Factors; Aged; Biomarkers; Cross-Sectional Studies; Diet; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Mental Recall; Middle Aged; Nutrition Surveys; Prevalence; Reference Values; Sex Factors; Spain; Surveys and Questionnaires; Vitamin B 12 | 2007 |
Hyperhomocysteinaemia, thrombosis and pernicious anaemia.
Topics: Adult; Aged; Anemia, Pernicious; Female; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Middle Aged; Thrombosis; Vitamin B 12 | 2006 |
High glucose and homocysteine synergistically affect the metalloproteinases-tissue inhibitors of metalloproteinases pattern, but not TGFB expression, in human fibroblasts.
Topics: Drug Synergism; Fibroblasts; Glucose; Homocysteine; Humans; Hyperhomocysteinemia; Metalloproteases; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta | 2006 |
[Factors influencing homocysteineamia in type 2 diabetic patients].
Topics: Diabetes Mellitus, Type 2; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Plasma homocysteine level and myocardial infarction: how high is high enough to need intervention?
Topics: Animals; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Myocardial Infarction; Prognosis; Risk Factors; Vitamin B Complex | 2006 |
Determinants of plasma homocysteine in relation to hematological and biochemical variables in patients with acute myocardial infarction.
Topics: Adult; Aged; Biomarkers; Blood Cell Count; Female; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Myocardial Infarction; Prognosis; Risk Factors; Sex Factors; Vitamins | 2006 |
Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance.
Topics: Aged; Animals; Apolipoprotein A-I; Apolipoproteins E; Biological Transport; Cells, Cultured; Cholesterol; Cholesterol, HDL; Coronary Artery Disease; Cystathionine; Hepatocytes; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Male; Mice; Mice, Knockout; Middle Aged | 2006 |
[The treatment of hyperhomocysteinemia in patients on dialysis: folic acid or the high-flow polysulphonic membrane?].
Topics: Adult; Aged; Aged, 80 and over; Biocompatible Materials; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Membranes, Artificial; Middle Aged; Polymers; Renal Dialysis; Sulfones; Vitamin B Complex | 2006 |
Higher plasma homocysteine concentration is associated with more advanced systemic arterial stiffness and greater blood pressure response to stress in hypertensive patients.
Topics: Adult; Aged; Arteries; Atherosclerosis; Blood Pressure; Elasticity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Pulsatile Flow; Stress, Physiological; Vascular Resistance | 2006 |
Homocysteine, folic acid and B12 serum levels in pregnancy complicated with preeclampsia.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Vitamin B 12 | 2007 |
Folic acid administration and antibodies against homocysteinylated proteins in subjects with hyperhomocysteinemia.
Topics: Alleles; Autoantibodies; Case-Control Studies; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Immunoglobulin G; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2006 |
The methylenetetrahydrofolate reductase C677T gene mutation is associated with hyperhomocysteinemia, cardiovascular disease and plasma B-type natriuretic peptide levels in Korea.
Topics: Aged; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Creatine Kinase; Creatinine; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Isoenzymes; Korea; L-Lactate Dehydrogenase; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Natriuretic Peptide, Brain; Troponin I | 2006 |
Hyperhomocysteinemia induces insulin resistance in male Sprague-Dawley rats.
Topics: Animals; Blood Glucose; Glucose Tolerance Test; Homocysteine; Hyperhomocysteinemia; Insulin; Insulin Resistance; Male; Rats; Rats, Sprague-Dawley; Time Factors | 2007 |
Homocysteine, traditional risk factors and impaired renal function in coronary artery disease.
Topics: Aged; Coronary Artery Disease; Diabetes Mellitus; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Obesity; Polymorphism, Genetic; Risk Factors; Vitamin B Complex | 2006 |
Increased plasma homocysteine and allantoin levels in coronary artery disease: possible link between homocysteine and uric acid oxidation.
Topics: Adult; Aged; Allantoin; Coronary Artery Disease; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Oxidation-Reduction; Reactive Oxygen Species; Uric Acid | 2006 |
Patient information. The importance of homocysteine.
Topics: Biological Availability; Cardiovascular Diseases; Causality; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Nurse Practitioners; Risk Reduction Behavior; Tetrahydrofolates | 2006 |
[Hyperhomocystinemia as a thrombotic risk factor in patients suffering from systemic lupus erithematosus and antiphospholipid syndrome].
Topics: Adult; Aged; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Argentina; Biomarkers; Case-Control Studies; Chi-Square Distribution; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lupus Erythematosus, Systemic; Male; Middle Aged; Pregnancy; Risk Factors; Thrombosis | 2005 |
Homocysteine, vitamin B12 and folate levels in premature coronary artery disease.
Topics: Adult; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Risk Factors; Sex Characteristics; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Low fasting methionine concentration as a novel risk factor for recurrent venous thrombosis.
Topics: Adult; Aged; Case-Control Studies; Cysteine; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Middle Aged; Multivariate Analysis; Odds Ratio; Recurrence; Risk Assessment; Risk Factors; Venous Thrombosis | 2006 |
Homocysteine lowering and cognitive performance.
Topics: Aged; Cognition; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex | 2006 |
[Homocysteine as a cardiovascular marker and risk factor].
Topics: Cause of Death; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Myocardial Infarction; Risk Factors; Secondary Prevention; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2006 |
Asymmetric dimethylarginine (ADMA) and hyperhomocysteinemia in patients with acute myocardial infarction.
Topics: Aged; Arginine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Regression Analysis; Risk Factors; Statistics, Nonparametric; Stereoisomerism | 2007 |
Hyperhomocysteinemia is associated with deep venous thrombosis of the lower extremities in Tunisian patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leg; Male; Middle Aged; Prevalence; Recurrence; Tunisia; Venous Thrombosis; Vitamin B 12 | 2007 |
[Homocysteinemia and thrombophilic factors in unexplained decompression sickness].
Topics: Adult; Decompression Sickness; Diving; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Reference Values; Thrombophilia; Vitamin B 12 Deficiency | 2006 |
[Ischemic, an uncommon complication of Biermer disease (pernicious anemia)].
Topics: Adult; Anemia, Pernicious; Brain; Female; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Magnetic Resonance Imaging | 2006 |
Hyperhomocysteinemia due to cystathionine beta synthase deficiency induces dysregulation of genes involved in hepatic lipid homeostasis in mice.
Topics: Animals; Base Sequence; Cholesterol; Cystathionine beta-Synthase; Disease Models, Animal; DNA Primers; Endoplasmic Reticulum; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Lipid Metabolism; Liver; Male; Mice; Mice, Knockout; Receptors, Cytoplasmic and Nuclear; RNA, Messenger | 2007 |
Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss.
Topics: Abortion, Habitual; Adolescent; Adult; Aged; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Thrombosis; Vitamin B 12 | 2007 |
Differential effects of low and high dose folic acid on endothelial dysfunction in a murine model of mild hyperhomocysteinaemia.
Topics: Animals; Clotrimazole; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mesenteric Arteries; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Vasodilation; Vasodilator Agents | 2006 |
Role of redox factor-1 in hyperhomocysteinemia-accelerated atherosclerosis.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Chemokine CCL2; Diet; DNA-(Apurinic or Apyrimidinic Site) Lyase; Female; Foam Cells; Homocysteine; Humans; Hyperhomocysteinemia; Macrophages, Peritoneal; Mice; Mice, Mutant Strains; Monocytes; NADP; NF-kappa B; Promoter Regions, Genetic; Protein Transport; Reactive Oxygen Species | 2006 |
[Increase of homocysteine in cardiovascular diseases in Hungary].
Topics: Adult; Aged; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; COUP Transcription Factor II; Diabetes Mellitus, Type 2; Factor XIII; Female; Folic Acid; Homocysteine; Humans; Hungary; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Patient Selection; Polymorphism, Genetic; Retrospective Studies; Risk Factors; Vitamin B 12 | 2006 |
Total homocysteine, folate, and cobalamin, and their relation to genetic polymorphisms, lifestyle and body mass index in healthy children and adolescents.
Topics: Adolescent; Aging; Blood Pressure; Body Mass Index; Child; Child, Preschool; Cholesterol; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Sex Characteristics; Triglycerides; Vitamin B 12 | 2006 |
Maternal hyperhomocysteinaemia is a risk factor for congenital heart disease.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Maternal Age; Pregnancy; Pregnancy Complications; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 2006 |
Prothrombotic effects of hyperhomocysteinemia and hypercholesterolemia in ApoE-deficient mice.
Topics: Animals; Apolipoproteins E; Body Weight; Cholesterol; Disease Susceptibility; Endothelium, Vascular; Gene Expression Regulation; Homocysteine; Hypercholesterolemia; Hyperhomocysteinemia; Male; Methionine; Mice; Mice, Knockout; Platelet Activation; Thrombosis | 2007 |
Effect of oral hormone replacement therapy on plasma homocysteine levels.
Topics: Administration, Oral; Adult; Cyproterone Acetate; Estradiol; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation | 2006 |
Plasma homocysteine and folate levels in patients with chronic plaque psoriasis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Chronic Disease; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Psoriasis | 2006 |
Preanalytical sources of measurement error: the conundrum of the homocysteine hypothesis.
Topics: Blood Chemical Analysis; Diagnostic Errors; Homocysteine; Humans; Hyperhomocysteinemia; Reproducibility of Results; Specimen Handling | 2007 |
Dietary intake of B-vitamins in mothers born a child with a congenital heart defect.
Topics: Adult; Case-Control Studies; Dietary Proteins; Educational Status; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Logistic Models; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Nutritional Status; Pregnancy; Pregnancy Complications; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2006 |
Serum sex hormone and plasma homocysteine levels in middle-aged and elderly men.
Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Dehydroepiandrosterone Sulfate; Estradiol; Fasting; Homocysteine; Hormones; Humans; Hyperhomocysteinemia; Male; Middle Aged; Sex Hormone-Binding Globulin; Testosterone | 2006 |
Hyperhomocysteinemia: a novel risk factor for erectile dysfunction.
Topics: Adult; Aged; Erectile Dysfunction; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Penis; Risk Factors; Ultrasonography | 2006 |
13N-ammonia rest/stress PET: folic acid improves global coronary vasoreactivity in coronary artery disease patients with normal or elevated homocysteine levels.
Topics: Aged; Ammonia; Coronary Angiography; Coronary Disease; Exercise Test; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitrogen Radioisotopes; Positron-Emission Tomography; Reference Values | 2006 |
Apolipoprotein E e4 allele affects risk of hyperhomocysteinemia in the elderly.
Topics: Aged; Aging; Alleles; Apolipoprotein E4; C-Reactive Protein; Cohort Studies; Confidence Intervals; Dementia; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, VLDL; Male; Odds Ratio; Prospective Studies; Risk Factors; Vascular Diseases | 2006 |
Hyperhomocysteinaemia is associated with the rate of abdominal aortic aneurysm expansion.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Aortic Rupture; Female; Follow-Up Studies; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Hypertension; Linear Models; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors | 2007 |
Role of hyperhomocystinemia in retinal vascular occlusive disease.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Retinal Artery Occlusion; Retinal Vein Occlusion; Risk Factors; Thrombophilia | 2007 |
A prospective patient observational study of the role of hyperhomocysteinemia in restenosis in patients undergoing infrainguinal angioplasty or bypass procedures.
Topics: Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Angioplasty; Atherosclerosis; Female; Groin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Recurrence | 2006 |
[The analysis of plasma homocysteine among 1020 residents in community].
Topics: China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Reference Values | 2006 |
Dimethylthetin treatment causes diffuse alveolar lung damage: a pilot study in a sheep model of Continuous Ambulatory Peritoneal Dialysis (CAPD).
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Dialysis Solutions; Disease Models, Animal; Glycine; Homocysteine; Hyperhomocysteinemia; Nephrectomy; Peritoneal Dialysis, Continuous Ambulatory; Pilot Projects; Pulmonary Alveoli; Renal Insufficiency; Sheep; Substrate Specificity | 2007 |
Methionine-loading and random homocysteine tests have no added value in risk assessment for venous and arterial thrombosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Cohort Studies; Fasting; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Methionine; Middle Aged; Netherlands; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Thrombosis; Time Factors; Venous Thrombosis | 2007 |
Homocysteine: an activity marker in Behçet's disease?
Topics: Acute Disease; Adult; Behcet Syndrome; Biomarkers; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Severity of Illness Index | 2007 |
Hyperhomocysteinemia and mortality after coronary artery bypass grafting.
Topics: Aged; Coronary Artery Bypass; Coronary Artery Disease; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors | 2006 |
Homocysteinylation of metallothionein impairs intracellular redox homeostasis: the enemy within!
Topics: Atherosclerosis; Betaine; Endothelium, Vascular; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Metallothionein; Oxidation-Reduction; Risk Factors; Vitamin B Complex | 2007 |
Predictive factors of hyperhomocysteinemia in HIV-positive patients.
Topics: Adult; Antiretroviral Therapy, Highly Active; Cross-Sectional Studies; Female; Folic Acid; HIV Infections; HIV Seropositivity; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2007 |
Hyperhomocysteinemia alters cardiac substrate metabolism by impairing nitric oxide bioavailability through oxidative stress.
Topics: Animals; Biological Availability; Blood Pressure; Dogs; Heart Rate; Homocysteine; Hyperhomocysteinemia; Male; Nitric Oxide; Oxidative Stress; Substrate Specificity | 2007 |
Homocysteine thiolactone-induced hyperhomocysteinemia does not alter concentrations of cholesterol and SREBP-2 target gene mRNAS in rats.
Topics: Animals; Cholesterol; Diet; Disease Models, Animal; Gene Expression; Homocysteine; Hydroxymethylglutaryl CoA Reductases; Hyperhomocysteinemia; Intestine, Small; Lipoproteins; Liver; Rats; Rats, Sprague-Dawley; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sterol Regulatory Element Binding Protein 2 | 2007 |
Hyperhomocysteinemia as a cardiovascular risk factor in Indian women: determinants and directionality.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Middle Aged; Risk Assessment; Risk Factors; Vitamin B 12 | 2006 |
High prevalence of hyperhomocysteinemia in Chinese adults is associated with low folate, vitamin B-12, and vitamin B-6 status.
Topics: Adult; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Prevalence; Risk Factors; Seasons; Vitamin B 12; Vitamin B 6 | 2007 |
Nitrous oxide promotes hyperhomocysteinemia in levodopa treated rats.
Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Catechols; Drug Interactions; Enzyme Inhibitors; Homocysteine; Hyperhomocysteinemia; Immunoassay; Levodopa; Male; Nitriles; Nitrous Oxide; Random Allocation; Rats; Rats, Wistar | 2007 |
Coffee and diabetes: is homocysteine the missing link?
Topics: Coffee; Diabetes Mellitus, Type 2; Homocysteine; Humans; Hyperhomocysteinemia; Multivariate Analysis; Regression Analysis | 2007 |
Hyperhomocysteinaemia and immune activation in patients with cancer.
Topics: Aged; Biomarkers; Case-Control Studies; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immune System; Male; Neoplasms; Neopterin; Vitamin B 12 | 2007 |
Assessment of homocysteine, neopterin and nitric oxide levels in Behçet's disease.
Topics: Adult; Behcet Syndrome; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neopterin; Nitric Oxide; Predictive Value of Tests; Recurrence; Stomatitis, Aphthous | 2007 |
Gestational vitamin B deficiency leads to homocysteine-associated brain apoptosis and alters neurobehavioral development in rats.
Topics: Animals; Apoptosis; Astrocytes; Behavior, Animal; Brain; Female; Homocysteine; Hyperhomocysteinemia; Maze Learning; Memory; Neurons; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Time Factors; Tumor Suppressor Protein p53; Vitamin B Deficiency | 2007 |
Altered renal folate handling in hypertensive patients with nephroangiosclerotic damage.
Topics: Case-Control Studies; Creatinine; Folic Acid; Genotype; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Renal; Ischemia; Methylenetetrahydrofolate Reductase (NADPH2); Nephrons; Renal Artery Obstruction; Vitamin B 12 | 2007 |
Hyperhomocysteinemia is associated with visceral adiposity in Japanese patients with type 2 diabetes mellitus.
Topics: Adipose Tissue; Aged; Diabetes Mellitus, Type 2; Echocardiography; Electrocardiography; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Japan; Male; Middle Aged; Viscera | 2007 |
Effects of catechin on homocysteine metabolism in hyperhomocysteinemic mice.
Topics: Administration, Oral; Animal Feed; Animals; Catechin; Cystathionine beta-Synthase; DNA Primers; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA; Superoxide Dismutase; Superoxide Dismutase-1 | 2007 |
[Neurological syndromes associated with homocystein dismetabolism].
Topics: Demyelinating Diseases; Diagnosis, Differential; Disease Progression; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Leukoencephalitis, Acute Hemorrhagic; Magnetic Resonance Imaging; Male; Middle Aged; Polyneuropathies; Prognosis; Risk Factors; Stroke | 2006 |
Hypertension in spontaneously hypertensive rats occurs despite low plasma levels of homocysteine.
Topics: Amino Acids; Animals; Chromatography, Ion Exchange; Disease Models, Animal; Down-Regulation; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2008 |
Evaluation of cardiovascular risk factors and related clinical markers in healthy young Japanese adults.
Topics: Adolescent; Adult; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carotid Arteries; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Regression Analysis; Risk Factors; Tunica Intima | 2007 |
Plasma homocysteine cutoff values for venous thrombosis.
Topics: Adult; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Venous Thrombosis | 2007 |
The angiotensin type 1 receptor antagonist valsartan attenuates pathological ventricular hypertrophy induced by hyperhomocysteinemia in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Homocysteine; Hyperhomocysteinemia; Hypertrophy, Left Ventricular; Male; Organ Size; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Ventricular Remodeling | 2006 |
Mutations in methylenetetrahydrofolate reductase or cystathionine beta-synthase gene, or a high-methionine diet, increase homocysteine thiolactone levels in humans and mice.
Topics: Animals; Cystathionine beta-Synthase; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mutation | 2007 |
By the way, doctor. How do B vitamins lower your homocysteine level, and how important is it to have a normal level?
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
DNA methylation status is not impaired in treated cystathionine beta-synthase (CBS) deficient patients.
Topics: Chromatography, Liquid; Cystathionine beta-Synthase; DNA; DNA Methylation; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Analysis, DNA; Spectrometry, Mass, Electrospray Ionization | 2007 |
Total cardiovascular risk profile of Taiwanese vegetarians.
Topics: C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cholesterol; Diet, Vegetarian; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Risk Assessment; Risk Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Branch retinal artery occlusion associated with compound heterozygous genotype for methylenetetrahydrofolate reductase.
Topics: Adult; Electroretinography; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Retinal Artery Occlusion; Tomography, Optical Coherence; Visual Field Tests; Visual Fields | 2007 |
Homocysteine and post-stroke cognitive decline.
Topics: Aged; Aged, 80 and over; Attention; Cognition; Cognition Disorders; Cohort Studies; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Logistic Models; Predictive Value of Tests; Recovery of Function; Stroke; Time Factors; Verbal Behavior | 2007 |
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.
Topics: Animals; Brain; Disease Models, Animal; Embryo, Mammalian; Female; Ferredoxin-NADP Reductase; Folic Acid; Heart; Homocysteine; Hyperhomocysteinemia; Kidney; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Homocysteine and methylenetetrahydrofolate reductase in subjects undergoing coronary angiography.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Genetic; Risk Factors; Severity of Illness Index | 2007 |
Hyperhomocysteinemia and low methionine stress are risk factors for central retinal venous occlusion in an Indian population.
Topics: Adult; Case-Control Studies; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methionine; Prevalence; Prospective Studies; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2007 |
Podocyte injury and glomerulosclerosis in hyperhomocysteinemic rats.
Topics: Actinin; Albuminuria; Animals; Creatinine; Glomerulosclerosis, Focal Segmental; Homocysteine; Hyperhomocysteinemia; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Methionine; Microfilament Proteins; Podocytes; Rats; Rats, Sprague-Dawley; Time Factors | 2007 |
No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanese.
Topics: Adult; Aged; Atherosclerosis; Atrophy; Female; Folic Acid; Gastric Mucosa; Genotype; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Smoking | 2007 |
Low vitamin B6, and not plasma homocysteine concentration, as risk factor for abdominal aortic aneurysm: a retrospective case-control study.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Case-Control Studies; Creatinine; DNA Mutational Analysis; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B 6 Deficiency | 2007 |
Apolipoprotein E polymorphism, homocysteine serum levels and hippocampal volume in patients with alcoholism: an investigation of a gene-environment interaction.
Topics: Adult; Alcoholism; Apolipoprotein E4; Environment; Female; Gene Frequency; Genetic Predisposition to Disease; Hippocampus; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Organ Size; Polymorphism, Genetic; Risk Factors | 2008 |
[Serum total homocysteine and lipoproteins levels in young adults from urban and rural areas of Costa Rica].
Topics: Adult; Biomarkers; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Costa Rica; Female; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Hypertriglyceridemia; Lipoproteins; Male; Metabolic Diseases; Prevalence; Risk Factors; Rural Population; Sex Distribution; Triglycerides; Urban Population | 2006 |
Liver-X-receptor activator prevents homocysteine-induced production of IgG antibodies from murine B lymphocytes via the ROS-NF-kappaB pathway.
Topics: Animals; Apolipoproteins E; B-Lymphocytes; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Homocysteine; Humans; Hydrocarbons, Fluorinated; Hyperhomocysteinemia; Immunoglobulin G; Leupeptins; Lipopolysaccharides; Liver X Receptors; Luciferases; Metalloporphyrins; Mice; Mice, Knockout; NF-kappa B; Orphan Nuclear Receptors; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Signal Transduction; Spleen; Sulfonamides; Time Factors; Transfection | 2007 |
Modification by homocysteine thiolactone affects redox status of cytochrome C.
Topics: Animals; Binding Sites; Circular Dichroism; Cytochromes c; Homocysteine; Horses; Hyperhomocysteinemia; Lysine; Oxidation-Reduction; Protein Processing, Post-Translational; Protein Structure, Secondary | 2007 |
Association of increased levels of homocysteine and peripheral arterial disease in a Japanese-Brazilian population.
Topics: Age Distribution; Aged; Asian People; Biomarkers; Body Mass Index; Brazil; Cholesterol; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Complications; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Japan; Male; Middle Aged; Obesity; Peripheral Vascular Diseases; Population Surveillance; Prevalence; Retrospective Studies; Risk Factors; Sex Distribution; Triglycerides | 2007 |
Short-term hyperhomocysteinemia-induced oxidative stress activates retinal glial cells and increases vascular endothelial growth factor expression in rat retina.
Topics: alpha-Tocopherol; Animals; Folic Acid; Glial Fibrillary Acidic Protein; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Male; Neuroglia; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Retina; Scavenger Receptors, Class E; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Vascular Endothelial Growth Factor A; Vimentin; Vitamin A | 2007 |
The organotellurium compound ammonium trichloro(dioxoethylene-o,o')tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice.
Topics: Animals; Apoptosis; DNA Fragmentation; Ethylenes; HL-60 Cells; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Spermatozoa | 2007 |
Homocysteine-induced biochemical stress predisposes to cytoskeletal remodeling in stretched endothelial cells.
Topics: Actins; Androstadienes; Animals; Biomechanical Phenomena; Cells, Cultured; Cytochalasin D; Cytoskeleton; Endothelial Cells; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Homocysteine; Hyperhomocysteinemia; Mice; Oxidative Stress; Paxillin; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Transport; rac GTP-Binding Proteins; rhoA GTP-Binding Protein; Wortmannin | 2007 |
[Case-control study evaluating the incidence of hyperhomocysteinemia in cancer patients in an internal medicine department].
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neoplasms | 2007 |
Mice lacking cystathionine beta synthase have lung fibrosis and air space enlargement.
Topics: Animals; Cell Differentiation; Cystathionine beta-Synthase; Disease Models, Animal; Fibroblasts; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Knockout; Polymerase Chain Reaction; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis | 2007 |
Can B vitamin therapy help to prevent future vascular events?
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2007 |
Antiepileptic drugs and MTHFR polymorphisms influence hyper-homocysteinemia recurrence in epileptic patients.
Topics: Adult; Age Factors; Anticonvulsants; Combined Modality Therapy; Epilepsy; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome | 2007 |
Association of plasma homocysteine with bone mineral density in postmenopausal women with osteoporosis or osteopenia affected by primary biliary cirrhosis.
Topics: Aged; Bone Density; Bone Diseases, Metabolic; Female; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis, Biliary; Middle Aged; Osteoporosis; Risk Factors | 2007 |
Homocysteine induces VCAM-1 gene expression through NF-kappaB and NAD(P)H oxidase activation: protective role of Mediterranean diet polyphenolic antioxidants.
Topics: Antioxidants; Cell Adhesion; Cells, Cultured; Diet, Mediterranean; Dose-Response Relationship, Drug; Endothelial Cells; Flavonoids; Homocysteine; Humans; Hyperhomocysteinemia; I-kappa B Proteins; Monocytes; Mutation; NADPH Oxidases; Phenols; Phenylethyl Alcohol; Phosphorylation; Polyphenols; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Transport; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor RelA; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2007 |
Mild hyperhomocysteinemia and low folate concentrations as risk factors for cervical arterial dissection.
Topics: Adolescent; Adult; Carotid Artery, Internal, Dissection; Case-Control Studies; Cerebral Arteries; Cerebral Infarction; Fasting; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Middle Aged; Nutritional Status; Odds Ratio; Polymorphism, Genetic; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Vertebral Artery Dissection; Vitamin B 12 | 2007 |
Migraine aura status and hyperhomocysteinaemia.
Topics: Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Migraine with Aura; Paresthesia; Polymorphism, Genetic; Scotoma | 2007 |
Hyperhomocysteinemia in winter elite athletes: a longitudinal study.
Topics: Adult; Cardiovascular Diseases; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Physical Exertion; Prevalence; Risk Factors; Seasons; Sex Distribution; Sports | 2007 |
Hyperhomocysteinemia and hypercoagulable state in carotid plaque evolution. Novel risk factors or coincidental risk predictors?
Topics: Aged; Antithrombin III; Blood Coagulation Factors; Carotid Artery Diseases; Female; Fibrinogen; Follow-Up Studies; Greece; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Incidence; Male; Prognosis; Protein C; Protein S; Receptors, Cell Surface; Retrospective Studies; Risk Factors; Thrombophilia; Ultrasonography, Doppler, Duplex | 2007 |
Plasma homocysteine and ischemic stroke patients in Thailand.
Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stroke; Thailand | 2007 |
Hyper-homocysteinemia alters amyloid peptide-clusterin interactions and neuroglial network morphology and function in the caudate after intrastriatal injection of amyloid peptides.
Topics: Amyloid beta-Peptides; Animals; Behavior, Animal; Benzothiazoles; Caudate Nucleus; Clusterin; Drug Interactions; Food, Formulated; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Models, Biological; Pain Measurement; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reaction Time; Thiazoles | 2007 |
Correlations between folate, B12, homocysteine levels, and radiological markers of neuropathology in elderly post-stroke patients.
Topics: Aged; Biomarkers; Brain; Brain Infarction; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mental Recall; Nutrition Assessment; Nutrition Policy; Stroke; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2007 |
Hyperhomocysteinemia and central retinal vein occlusion in Iranian population.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Male; Middle Aged; Odds Ratio; Retinal Vein Occlusion; Risk Factors | 2008 |
Does lowering hyperhomocysteinemia by folic acid beneficial for oculo-Behcet's disease? A pilot study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Behcet Syndrome; Cyclophosphamide; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Male; Middle Aged; Pilot Projects; Prospective Studies; Retinal Vasculitis; Uveitis; Visual Acuity; Vitamin B Complex | 2007 |
Folate deficiency and plasma homocysteine during increased oxidative stress.
Topics: Alzheimer Disease; Animals; Apolipoproteins E; Cardiovascular Diseases; Disease Models, Animal; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Transgenic; Oxidative Stress; Risk Factors | 2007 |
Homocysteinemia as an independent risk factor in the Chinese population at a high risk of coronary artery disease.
Topics: China; Coronary Artery Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors | 2007 |
[Hyperhomocysteinemia in coronary artery disease and hemostasis disorders in patients with type 2 diabetes mellitus].
Topics: Blood Coagulation; Blood Platelets; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Tomography, Spiral Computed | 2007 |
B-vitamins and homocysteine in Spanish institutionalized elderly.
Topics: Aged; Aged, 80 and over; Aging; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Institutionalization; Male; Middle Aged; Regression Analysis; Sex Characteristics; Spain; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 2007 |
The relation between plasma homocysteine level and cardiovascular risk factors in cerebral ischemia.
Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Cardiovascular Diseases; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Retrospective Studies; Risk Factors | 2007 |
Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia.
Topics: Animals; Animals, Genetically Modified; Aorta; Apolipoprotein A-I; Betaine; Cholesterol; Disease Models, Animal; Fatty Liver; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Lipotropic Agents; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Time; Triglycerides; Tyrosine | 2007 |
Does homocysteine-lowering treatment improve cardiovascular outcomes in patients with acute coronary syndromes? What we have learned from clinical trials?
Topics: Acute Coronary Syndrome; Clinical Trials as Topic; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Prognosis; Risk Assessment; Treatment Outcome | 2008 |
Polymorphisms of apolipoprotein e and methylenetetrahydrofolate reductase in the Japanese population.
Topics: Apolipoproteins E; Asian People; Data Collection; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Japan; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Sex Distribution | 2007 |
Effect of hyperhomocysteinemia on cardiovascular risk factors and initiation of atherosclerosis in Wistar rats.
Topics: Animals; Aorta; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; Caveolin 2; Cholesterol; Cysteine; Homocysteine; Hydroxymethylglutaryl CoA Reductases; Hyperhomocysteinemia; In Vitro Techniques; Leukotrienes; Liver; Male; Methionine; Nitric Oxide; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2Y2; Resistin; Tunica Media | 2007 |
Homocysteine (Hcy) follow-up study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2007 |
Transient global amnesia-like episode in a patient with severe hyperhomocysteinemia.
Topics: Amnesia, Transient Global; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2007 |
Metabolic syndrome and hyperhomocysteinemia in patients with deep vein thrombosis: a case-control study.
Topics: Aged; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolic Syndrome; Middle Aged; Odds Ratio; Prevalence; Risk Factors; Venous Thrombosis | 2007 |
Hyperhomocysteinemia-mediated DNA hypomethylation and its potential epigenetic role in rats.
Topics: Animals; Atherosclerosis; Base Sequence; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Homocysteine; Hyperhomocysteinemia; Male; Mice; Molecular Sequence Data; Rabbits; Rats; Rats, Sprague-Dawley | 2007 |
Experimental hyperhomocysteinemia disturbs bone metabolism in rats.
Topics: Animals; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Collagen Type I; Creatine; Female; Folic Acid; Homocysteine; Hydroxyproline; Hyperhomocysteinemia; Methionine; Osteocalcin; Osteogenesis; Peptides; Rats; Rats, Wistar; Vitamin B 12 | 2007 |
Cystathionine-beta-synthase gene transfer and 3-deazaadenosine ameliorate inflammatory response in endothelial cells.
Topics: Animals; Cell Adhesion Molecules; Cells, Cultured; Collagen Type I; Cystathionine beta-Synthase; Endothelial Cells; Extracellular Matrix; Genetic Therapy; Homocysteine; Hyperhomocysteinemia; Inflammation Mediators; Matrix Metalloproteinase 9; Methionine; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Transfection; Tubercidin | 2007 |
Increased plasma homocysteine levels in multiple sclerosis.
Topics: Adult; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multiple Sclerosis | 2007 |
Impact of hypertension and hyperhomocysteinemia on arterial thrombosis in primary antiphospholipid syndrome.
Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Autoantibodies; Case-Control Studies; Coronary Artery Disease; Endothelin-1; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipoprotein Lipase; Lipoproteins, LDL; Middle Aged; Risk Factors; Thrombosis | 2007 |
Homocysteine and epigenetic DNA methylation: a biological model for depression?
Topics: Depressive Disorder; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological | 2007 |
Homocysteine in restless legs syndrome.
Topics: Aged; Antiparkinson Agents; Catechols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Reference Values; Restless Legs Syndrome; Vitamin B 12; Vitamin B 6 | 2008 |
Serum homocysteine levels in renal transplant recipients with and without hypercholesterolemia.
Topics: Adult; Age Factors; Biomarkers; Brazil; Cholesterol; Creatinine; Cyclosporine; Dyslipidemias; Epidemiologic Methods; Female; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Proteinuria; Reference Values; Time Factors; Triglycerides | 2007 |
Effect of MTHFR polymorphisms on hyperhomocysteinemia in levodopa-treated Parkinsonian patients.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; Vitamin B 12 | 2007 |
Oral challenge with a methionine load in patients with inflammatory bowel disease: a better test to identify hyperhomocysteinemia.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Inflammatory Bowel Diseases; Male; Methionine; Middle Aged; Prevalence; Prognosis; Prospective Studies; Risk Factors; Thrombosis; Vitamin B 12 | 2008 |
Immunoregulatory effects of homocysteine on cardiovascular diseases.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Macrophages; Nitric Oxide; Oxidative Stress | 2007 |
Homocysteine induces connective tissue growth factor expression in vascular smooth muscle cells.
Topics: Animals; Cells, Cultured; Connective Tissue Growth Factor; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Methionine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors; Umbilical Veins | 2008 |
Homocysteine threshold value based on cystathionine beta synthase and paraoxonase 1 activities in mice.
Topics: Animals; Aryldialkylphosphatase; Cystathionine beta-Synthase; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Liver; Mice | 2007 |
Correlation of hyperhomocysteinaemia and Chlamydia pneumoniae IgG seropositivity with coronary artery disease in a general population.
Topics: Adult; Aged; Antibodies, Bacterial; C-Reactive Protein; Case-Control Studies; Chlamydophila Infections; Chlamydophila pneumoniae; Cohort Studies; Coronary Artery Disease; Electrocardiography; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Hyperhomocysteinemia; Immunoglobulin G; Information Systems; Male; Middle Aged | 2007 |
Homocysteine stimulates monocyte chemoattractant protein-1 expression in the kidney via nuclear factor-kappaB activation.
Topics: Animals; Cells, Cultured; Chemokine CCL2; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Tubules, Proximal; Male; Methionine; NF-kappa B; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2008 |
Hyperhomocysteinemia in women with advanced breast cancer.
Topics: Breast Neoplasms; Cohort Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Neoplasm Metastasis; Neoplasm Staging; Venous Thromboembolism | 2007 |
Synergism between AT1 receptor and hyperhomocysteinemia during vascular remodeling.
Topics: Animals; Blood Vessels; Blotting, Western; Cells, Cultured; Collagen Type I; Endothelium, Vascular; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, Angiotensin, Type 1; STAT3 Transcription Factor | 2007 |
Homocysteine induces tau hyperphosphorylation in rats.
Topics: Alzheimer Disease; Animals; Binding Sites; Brain; Brain Chemistry; Homocysteine; Hyperhomocysteinemia; Injections, Intraventricular; Male; Neurofibrillary Tangles; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; Serine; tau Proteins; Time Factors | 2007 |
Concurrent folate treatment prevents Na+,K+-ATPase activity inhibition and memory impairments caused by chronic hyperhomocysteinemia during rat development.
Topics: Aging; Animals; Chronic Disease; Cognition; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Motor Activity; Nerve Tissue Proteins; Parietal Lobe; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Space Perception; Synaptic Membranes; Thiobarbituric Acid Reactive Substances; Vitamins | 2007 |
Homocysteine induces monocyte chemoattractant protein-1 expression in hepatocytes mediated via activator protein-1 activation.
Topics: Animals; Base Sequence; Chemokine CCL2; DNA; Gene Expression Regulation; Hepatocytes; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Liver; Molecular Sequence Data; NF-kappa B p50 Subunit; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger; Transcription Factor AP-1; Transcription Factor RelA | 2008 |
Modulation of erythrocyte sensitivity to oxidative stress by transient hyperhomocysteinemia in healthy subjects and in patients with coronary artery disease.
Topics: Adult; Aged; alpha-Tocopherol; Analysis of Variance; Area Under Curve; Coronary Artery Disease; Erythrocytes; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Male; Methionine; Middle Aged; Oxidation-Reduction; Oxidative Stress | 2008 |
Polymorphism in the methylenetetrahydrofolate reductase (C677T) gene and homocysteine levels: a comparison in Brazilian patients with coronary arterial disease, ischemic stroke and peripheral arterial obstructive disease.
Topics: Aged; Amino Acid Substitution; Arterial Occlusive Diseases; Brain Ischemia; Brazil; Comorbidity; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Peripheral Vascular Diseases; Polymorphism, Single Nucleotide; Risk Factors | 2009 |
Differential associations between lipid-lowering drugs, statins and fibrates, and venous thromboembolism: role of drug induced homocysteinemia?
Topics: Aged; Aged, 80 and over; Case-Control Studies; Clofibric Acid; Databases, Factual; Female; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Hypolipidemic Agents; Male; Middle Aged; Risk Factors; Surveys and Questionnaires; Venous Thromboembolism | 2008 |
The association between cysteine, bone turnover, and low bone mass.
Topics: Aged; Aged, 80 and over; Bone Density; Cohort Studies; Collagen Type I; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Peptides | 2007 |
Effects of a B-vitamin-deficient diet on exploratory activity, motor coordination, and spatial learning in young adult Balb/c mice.
Topics: Age Factors; Aging; Animals; Body Weight; Brain; Disease Models, Animal; Drinking; Eating; Exploratory Behavior; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Hyperkinesis; Learning Disabilities; Male; Memory Disorders; Mice; Motor Skills Disorders; Movement; Movement Disorders; Space Perception; Vitamin B 12 Deficiency; Vitamin B Deficiency | 2008 |
Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats.
Topics: Animals; Aorta, Thoracic; Cell Line; Cells, Cultured; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Male; Methionine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides | 2007 |
The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels.
Topics: Aged; Coronary Artery Disease; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Turkey; Vitamin B 12 | 2008 |
Association of polymorphism in the thermolabile 5, 10-methylene tetrahydrofolate reductase gene and hyperhomocysteinemia with coronary artery disease.
Topics: Coronary Artery Disease; Enzyme Stability; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Phenotype; Polymorphism, Single Nucleotide; Regression Analysis | 2008 |
Hyperhomocysteinemia is associated with cognitive impairment in multiple sclerosis.
Topics: Age of Onset; Brain; Cognition Disorders; Disability Evaluation; Disease Progression; Folic Acid; Homocysteine; Hyperhomocysteinemia; Multiple Sclerosis; Multivariate Analysis; Neuropsychological Tests; Predictive Value of Tests; Up-Regulation; Vitamin B 12 Deficiency | 2008 |
Effect of folate, vitamin B6, and vitamin B12 intake and MTHFR C677T polymorphism on homocysteine concentrations of renal transplant recipients.
Topics: Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Kidney Transplantation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Postoperative Complications; Vitamin B 12; Vitamin B 6 | 2007 |
Is homocysteine toxic in uremia?
Topics: Acetylcysteine; Antitoxins; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Myocardial Infarction; Recurrence; Reference Values; Renal Dialysis; Retrospective Studies; Risk Factors; Uremia | 2008 |
The methionine connection: homocysteine and hydrogen sulfide exert opposite effects on hepatic microcirculation in rats.
Topics: Acetylcholine; Animals; Disease Models, Animal; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Liver; Liver Circulation; Liver Cirrhosis; Male; Methionine; Microcirculation; Rats; Rats, Wistar | 2008 |
Inhibitory effect of Ginkgo biloba extract on hyperhomocysteinemia-induced intimal thickening in rabbit abdominal aorta after balloon injury.
Topics: Animals; Aorta, Abdominal; Blotting, Western; Catheterization; Cyclin-Dependent Kinase Inhibitor p21; Ginkgo biloba; Homocysteine; Hyperhomocysteinemia; Male; Matrix Metalloproteinase 9; Plant Extracts; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tunica Intima; Vascular Diseases | 2008 |
Inhibition of adiponectin production by homocysteine: a potential mechanism for alcoholic liver disease.
Topics: Adiponectin; Adipose Tissue; Animals; Betaine; Cystathionine beta-Synthase; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Homocysteine; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methionine; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Rats; Rats, Sprague-Dawley | 2008 |
Homocysteine levels in epileptic children receiving antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Oxcarbazepine; Valproic Acid; Vitamin B 12 | 2007 |
Cytochrome P450 (CYP) 2J2 gene transfection attenuates MMP-9 via inhibition of NF-kappabeta in hyperhomocysteinemia.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Cells, Cultured; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Induction; Homocysteine; Hyperhomocysteinemia; I-kappa B Proteins; Matrix Metalloproteinase 9; Mice; NF-KappaB Inhibitor alpha; Oxygenases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Transcription Factor RelA; Transfection | 2008 |
A comparison of some of the cardiovascular risk factors in vegetarian and omnivorous Turkish females.
Topics: Adult; Cardiovascular Diseases; Diet; Diet Records; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Nutritional Status; Risk Factors; Turkey; Vitamin B 12 | 2008 |
Homocysteine upregulates resistin production from adipocytes in vivo and in vitro.
Topics: Adipocytes; Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Epididymis; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Protein Kinase C; Resistin | 2008 |
Elevated plasma homocysteine levels in patients with amyotrophic lateral sclerosis.
Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Biomarkers; Central Nervous System; Comorbidity; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nerve Degeneration; Predictive Value of Tests; Risk Factors; Sensitivity and Specificity; Up-Regulation; Vitamin B 12 | 2008 |
Hyperhomocysteinemia and recurrent carotid stenosis.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Carotid Stenosis; Case-Control Studies; Constriction, Pathologic; Endarterectomy, Carotid; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Probability; Recurrence; Reference Values; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Sex Factors; Ultrasonography, Doppler, Duplex | 2008 |
Homocysteinemia correlates with plasma thiol redox status in patients with end-stage renal disease.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cysteine; Dialysis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Oxidation-Reduction; Statistics, Nonparametric; Sulfhydryl Compounds; Vitamin B Complex | 2008 |
Homocysteine is a potent modulator of plasma membrane electron transport systems.
Topics: Animals; Antineoplastic Agents; Cardiovascular Diseases; Cattle; Cell Line, Tumor; Cell Membrane; Electron Transport; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; NADPH Oxidases; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Risk Factors | 2008 |
Sport-related hyperhomocysteinaemia: a putative marker of muscular demand to be noted for cardiovascular risk.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Cholesterol, HDL; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Interleukin-6; L-Lactate Dehydrogenase; Male; Muscle, Skeletal; Risk Factors; Sports; Vitamin B 12 | 2008 |
Does homocysteine contribute to bone disease in hyperparathyroidism?
Topics: Biomarkers; Bone and Bones; Bone Density; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hyperparathyroidism; Kidney Diseases; Male; Middle Aged; Osteoporosis; Parathyroidectomy; Prospective Studies | 2008 |
Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Chromatography, High Pressure Liquid; Electrochemistry; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Valproic Acid; Vitamin B 12 | 2008 |
Total homocysteine, B-vitamins and genetic polymorphisms in patients with classical phenylketonuria.
Topics: Adolescent; Adult; Body Mass Index; Child; Child, Preschool; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Phenylketonurias; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6; Vitamin B Deficiency | 2008 |
Comparison of the effect of different homocysteine concentrations on clot formation using human plasma and purified fibrinogen.
Topics: Blood Coagulation; Factor XIII; Fibrin; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia | 2008 |
Determinants and associations of homocysteine and prothrombotic risk factors in Kuwaiti patients with cerebrovascular accident.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kuwait; Logistic Models; Male; Middle Aged; Risk Factors; Stroke; Thrombophilia | 2008 |
Hyperhomocysteinaemia is a significant risk factor for white matter lesions in Japanese type 2 diabetic patients.
Topics: Blood Glucose; Brain Diseases; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Japan; Logistic Models; Male; Middle Aged; Neuroglia; Risk Factors | 2008 |
Effects of moderate hyperhomocysteinaemia induced by 4 weeks methionine-enriched diet on metabolite profile and mesenteric artery function in rats.
Topics: Animals; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Diet; Homocysteine; Hyperhomocysteinemia; Male; Mesenteric Arteries; Methionine; Rats; Rats, Wistar; Vasodilation | 2008 |
Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Diet Records; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 2008 |
Protective effect against alcohol dependence of the thermolabile variant of MTHFR.
Topics: Alcohol Drinking; Alcoholic Neuropathy; Alcoholism; Control Groups; Female; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Vitamin B 12 | 2008 |
Methionine loading does not enhance the predictive value of homocysteine serum testing for all-cause mortality or major adverse cardiac events.
Topics: Adult; Female; Heart Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Predictive Value of Tests | 2009 |
Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice.
Topics: Animals; Atherosclerosis; Diet, Atherogenic; Dietary Supplements; Disease Models, Animal; Female; Homocysteine; Hyaluronic Acid; Hyperhomocysteinemia; Immunohistochemistry; Lipids; Methionine; Mice; Mice, Inbred C57BL | 2008 |
Methylenetetrahydrofolate reductase gene, homocysteine and coronary artery disease: the A1298C polymorphism does matter. Inferences from a case study (Madeira, Portugal).
Topics: Adult; Aged; Alleles; Case-Control Studies; Coronary Artery Disease; Female; Gene Frequency; Genotype; Haplotypes; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Portugal; Risk Factors | 2008 |
Assessment of cardiovascular risk in shift healthcare workers.
Topics: Adult; Aged; Cardiovascular Diseases; Circadian Rhythm; Female; Health Personnel; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Metabolic Syndrome; Middle Aged; Occupational Diseases; Prevalence; Risk Assessment; Risk Factors; Work Schedule Tolerance | 2008 |
Hopeful for a second HOPE-2 post hoc analysis.
Topics: Chronic Disease; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Randomized Controlled Trials as Topic; Vitamin B Complex | 2008 |
Plasma homocysteine levels & 677C-->T methylenetetrahydrofolate reductase gene polymorphism in patients with coronary artery disease of different severity.
Topics: Aged; Atherosclerosis; Coronary Artery Disease; Demography; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2008 |
Homocysteine, folate and cognition in a large community-based sample of elderly people--the 3C Dijon Study.
Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; France; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Prospective Studies; Residence Characteristics; Risk Factors; Urban Health | 2008 |
Hyperhomocysteinaemia-induced cardiovascular changes in rats.
Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Disease Models, Animal; Heart Rate; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Nitroprusside; Phenylephrine; Rats, Wistar; Sympathetic Nervous System; Tachycardia; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Hyperhomocysteinemia and occlusive vascular disease: an emergent role for fibroblast growth factor 2.
Topics: Animals; Arterial Occlusive Diseases; Endothelium, Vascular; Fibroblast Growth Factor 2; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia | 2008 |
Post-methionine load test: A more sensitive tool to reveal hyperhomocysteinemia in Alzheimer patients?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Sensitivity and Specificity | 2008 |
Cystathionine beta-synthase p.S466L mutation causes hyperhomocysteinemia in mice.
Topics: Animals; Cystathionine beta-Synthase; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Transgenic; Mutation; Saccharomyces cerevisiae | 2008 |
Severe atherosclerosis in rheumatoid arthritis and hyperhomocysteinemia: is there a link?
Topics: Arthritis, Rheumatoid; Atherosclerosis; Female; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Risk Factors; Severity of Illness Index | 2008 |
Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study.
Topics: Aged; Atrophy; Biomarkers; Brain Infarction; Cerebral Cortex; Cohort Studies; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Massachusetts; Middle Aged; Nerve Degeneration; Nerve Fibers, Myelinated; Predictive Value of Tests; Prognosis | 2008 |
The homocysteine paradox.
Topics: Animals; Arginine; Cardiovascular Diseases; Cystatin C; Cystatins; Disease Models, Animal; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
The influence of MTR A2756G polymorphism on plasma homocysteine in young south Indians.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Molecular Sequence Data; Polymorphism, Genetic; Prevalence; Reference Values | 2008 |
Anesthetic management of a parturient with hyperhomocysteinemia.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Inhalation; Anticoagulants; Blood Coagulation; Blood Coagulation Tests; Blood Loss, Surgical; Cesarean Section; Drug Administration Schedule; Enoxaparin; Female; Heparin; Homocysteine; Humans; Hyperhomocysteinemia; Live Birth; Nitrous Oxide; Parturition; Pregnancy; Pregnancy Complications, Hematologic | 2008 |
The diagnostic value of serum homocysteine concentration as a risk factor for coronary artery disease.
Topics: Coronary Disease; Demography; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Lipids; Lipoproteins; Male; Middle Aged; Odds Ratio; Retrospective Studies; Risk Factors; ROC Curve; Surveys and Questionnaires; Vitamin B 12 | 1998 |
[The recommended daily intake of folic acid is insufficient for optimum homocysteine level].
Topics: Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 1998 |
Improvement of coronary artery disease in a patient with hyperhomocysteinemia: report of a case.
Topics: Adult; Angiography; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia | 1998 |
[Homocysteine, 5,10-methylenetetrahydrofolate reductase and deep venous thrombosis. Survey of 120 patients in internal medicine].
Topics: Adult; Aged; Antithrombin III; Chromatography, Ion Exchange; Data Interpretation, Statistical; Female; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Protein C; Protein S; Risk Factors; Serine Proteinase Inhibitors; Surveys and Questionnaires; Venous Thrombosis | 1998 |
Venous thrombosis and hyperhomocysteinaemia.
Topics: Adult; Anticoagulants; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Recurrence; Risk Factors; Venous Thrombosis; Vitamin B 12 | 1998 |
High expression, purification, and properties of recombinant homocysteine alpha, gamma-lyase.
Topics: Animals; Carbon-Sulfur Lyases; Cardiovascular Diseases; Chromatography; Cloning, Molecular; Cysteine; Enzyme Stability; Escherichia coli; Homocysteine; Hydrogen-Ion Concentration; Hyperhomocysteinemia; Kinetics; Methionine; Protein Conformation; Protozoan Proteins; Pseudomonas putida; Pyridoxal Phosphate; Recombinant Proteins; Substrate Specificity; Temperature; Trichomonas vaginalis | 1998 |
Homocysteine and folate in healthy east London Bangladeshis.
Topics: Adult; Aged; Bangladesh; Case-Control Studies; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; London; Male; Middle Aged; White People | 1998 |
Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation.
Topics: Adult; Endothelium, Vascular; Female; Fibronectins; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Risk Factors | 1998 |
Modulatory impact of cardiac rehabilitation on hyperhomocysteinemia in patients with coronary artery disease and "normal" lipid levels.
Topics: Aged; Coronary Disease; Exercise; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Treatment Outcome | 1998 |
Ocular venous occlusion and hyperhomocysteinemia.
Topics: Aged; Eye; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Venous Insufficiency | 1999 |
Homocysteine and cardiovascular disease. Overview.
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors | 1998 |
Homocysteine levels and coronary heart disease in Syria.
Topics: Adult; Aged; Case-Control Studies; Coronary Angiography; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Syria | 1998 |
Prospective blinded study of the relationship between plasma homocysteine and progression of symptomatic peripheral arterial disease.
Topics: Aged; Analysis of Variance; Arteriosclerosis; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Artery Disease; Disease Progression; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mortality; Multivariate Analysis; Peripheral Vascular Diseases; Prospective Studies; Risk Factors; Single-Blind Method | 1999 |
Plasma homocysteine levels in indigenous Australians.
Topics: Adult; Age Distribution; Cardiovascular Diseases; Creatine; Cross-Sectional Studies; Female; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Native Hawaiian or Other Pacific Islander; Queensland; Risk Factors; Sex Distribution; Smoking; Urban Health; Vitamin B 12 Deficiency | 1999 |
Response of hyperhomocysteinemia to folic acid supplementation in patients with end-stage renal disease.
Topics: Adult; Erythrocytes; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Middle Aged; Peritoneal Dialysis; Renal Dialysis | 1999 |
[A hyperhomocysteinemia study in a population with a familial factor for acute myocardial infarct and sudden cardiac death at a young age].
Topics: Adult; Age Factors; Aged; Case-Control Studies; Chi-Square Distribution; Death, Sudden, Cardiac; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Middle Aged; Myocardial Infarction; Risk Factors; Sex Characteristics | 1999 |
Prevalence and determinants of hyperhomocysteinemia in hemodialysis and peritoneal dialysis.
Topics: Creatinine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Peritoneal Dialysis; Prevalence; Pyridoxine; Renal Dialysis; Smoking; Time Factors; Vitamin B 12 | 1999 |
Genetic causes of mild hyperhomocysteinemia in patients with premature occlusive coronary artery diseases.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Age of Onset; Coronary Disease; Cystathionine beta-Synthase; Fasting; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic | 1999 |
Combination of low-dose folic acid and pyridoxine for treatment of hyperhomocysteinaemia in patients with premature arterial disease and their relatives.
Topics: Adult; Age of Onset; Arteriosclerosis; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Prospective Studies; Pyridoxine; Risk Factors | 1999 |
Thermolabile methyltetrahydrofolate reductase associated with unusual venous and arterial thromboses.
Topics: Adult; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Thrombosis; Venous Thrombosis | 1999 |
Hyperhomocysteinemia: a risk factor for ischemic stroke in children.
Topics: Adolescent; Adult; Biomarkers; Brain Ischemia; Case-Control Studies; Child; Child, Preschool; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Netherlands; Reference Values; Risk Factors | 1999 |
Hyperhomocysteinemia and hypofibrinolysis in young adults with ischemic stroke.
Topics: Adolescent; Adult; Brain Ischemia; Case-Control Studies; Cerebral Arteries; Cerebrovascular Disorders; Female; Fibrinolysis; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NAD+); Mutation; Oxidoreductases; Risk Factors; Vitamins | 1999 |
Peritoneal elimination of homocysteine moieties in continuous ambulatory peritoneal dialysis patients.
Topics: Adult; Ascitic Fluid; Creatinine; Dialysis Solutions; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory | 1999 |
Homocysteine and arteriosclerosis: subclinical and clinical disease associations.
Topics: Adolescent; Adult; Animals; Arteriosclerosis; Child; Child, Preschool; Comorbidity; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Middle Aged; Prevalence; Primates; Risk Factors; Swine; Swine, Miniature; Thrombophilia | 1999 |
Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
Topics: Adult; Aged; Amino Acid Substitution; Arteriosclerosis; Carotid Arteries; Carotid Stenosis; Comorbidity; Diet; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Obesity; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Pyridoxine; Risk Factors; Smoking; Tunica Intima; Ultrasonography; Vitamin B 12; Western Australia | 1999 |
Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.
Topics: Adult; Age Factors; Amino Acid Substitution; Arteriosclerosis; Body Mass Index; Comorbidity; Fasting; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipids; Male; Menopause; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pyridoxine; Smoking; Vitamin B 12 | 1999 |
Homocyst(e)ine and atherosclerosis in patients on chronic hemodialysis.
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Chronic Disease; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Dialysis; Risk Factors | 1999 |
[Obstetric problems followed by stroke].
Topics: Abortion, Habitual; Adult; Arteriosclerosis; Cerebral Infarction; Diagnosis, Differential; Female; Fetal Death; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Male; Methionine; Nutrition Disorders; Placental Insufficiency; Pregnancy; Pregnancy Complications, Cardiovascular; Pyridoxine; Smoking; Venous Thrombosis; Vitamin B 6 Deficiency | 1999 |
Effect of immunosuppressive therapy, serum creatinine, and time after transplant on plasma total homocysteine in patients following heart transplantation.
Topics: Adolescent; Adult; Aged; Cerebrovascular Disorders; Coronary Disease; Creatinine; Female; Follow-Up Studies; Graft Rejection; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Male; Middle Aged; Prevalence; Retrospective Studies; Survival Rate; Time Factors; Treatment Outcome | 1999 |
Recommended approaches for the laboratory measurement of homocysteine in the diagnosis and monitoring of patients with hyperhomocysteinaemia.
Topics: Adolescent; Adult; Aged; Child; Chromatography, High Pressure Liquid; Clinical Chemistry Tests; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Monitoring, Physiologic; Practice Guidelines as Topic | 1999 |
Effect of usual doses of folate supplementation on elevated plasma homocyst(e)ine in hemodialysis patients: no difference between 1 and 5 mg daily.
Topics: Aged; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors | 1999 |
Hyperhomocysteinaemia and upper extremity deep venous thrombosis: a case report.
Topics: Adult; Aerospace Medicine; Axillary Vein; Causality; Dehydration; Disability Evaluation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Military Personnel; Occupational Diseases; Physical Exertion; Recurrence; South Australia; Subclavian Vein; Ultrasonography; Venous Thrombosis | 1999 |
Prevalence of mild fasting hyperhomocysteinemia in renal transplant versus coronary artery disease patients after fortification of cereal grain flour with folic acid.
Topics: Coronary Disease; Fasting; Female; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Vitamin B 12 | 1999 |
Total homocysteine and cognitive decline in a community-based sample of elderly subjects: the Rotterdam Study.
Topics: Aged; Cognition Disorders; Dementia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Netherlands; Prospective Studies; Random Allocation; Risk Factors; Sensitivity and Specificity | 1999 |
Homocysteine. More answers...and questions.
Topics: Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B Complex | 1999 |
Normohomocysteinaemia and vitamin-treated hyperhomocysteinaemia are associated with similar risks of cardiovascular events in patients with premature peripheral arterial occlusive disease. A prospective cohort study.
Topics: Adult; Age of Onset; Aged; Arterial Occlusive Diseases; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Pyridoxine; Risk; Risk Factors | 1999 |
Evaluation of hyperhomocysteinaemia in children with stroke.
Topics: Adolescent; Anticonvulsants; Cerebrovascular Disorders; Child; Child, Preschool; Chromatography, High Pressure Liquid; Epilepsy; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Odds Ratio; Risk Assessment | 1999 |
Normalization of hyperhomocysteinemia with L-thyroxine in hypothyroidism.
Topics: Adult; Aged; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypothyroidism; Male; Middle Aged; Prospective Studies; Thyroxine | 1999 |
Homocysteine in health and disease.
Topics: Cardiovascular Diseases; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 1999 |
Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans.
Topics: Acetylcholine; Adult; Antioxidants; Ascorbic Acid; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Nitroprusside; Oxidative Stress; Vasodilation; Vasodilator Agents; Verapamil | 1999 |
Molecular basis for methionine synthase reductase deficiency in patients belonging to the cblE complementation group of disorders in folate/cobalamin metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; DNA Mutational Analysis; DNA, Complementary; Enzyme Activation; Ferredoxin-NADP Reductase; Folic Acid; Genes, Recessive; Genetic Complementation Test; Heteroduplex Analysis; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Mutation; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA Splicing; Sequence Analysis, DNA; Vitamin B 12 | 1999 |
Homocysteine and coronary artery disease.
Topics: Biomarkers; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Pteroylpolyglutamic Acids; Risk Factors; Severity of Illness Index | 1999 |
Influence of homocysteine on matrix metalloproteinase-2: activation and activity.
Topics: Cysteine; Enzyme Activation; Enzyme Precursors; Gelatin; Gelatinases; Glutathione; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinase 2; Metalloendopeptidases; Methionine | 1999 |
Folic acid fortification.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B Complex | 1999 |
Hyperhomocyst(e)inemia and the prevalence of atherosclerotic vascular disease in patients with end-stage renal disease.
Topics: Aged; Arteriosclerosis; Coronary Artery Disease; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Odds Ratio; Renal Dialysis; Retrospective Studies; Risk Factors; Sex Factors; Vitamin B 12 | 1999 |
N -Acetyl-cysteine reduces homocysteine plasma levels after single intravenous administration by increasing thiols urinary excretion.
Topics: Acetylcysteine; Aged; Aged, 80 and over; Cysteine; Female; Free Radical Scavengers; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 1999 |
Familial hyperhomocysteinaemia and endothelium-dependent vasodilatation and arterial distensibility of large arteries.
Topics: Adult; Brachial Artery; Carotid Artery, Common; Endothelium, Vascular; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Regional Blood Flow; Regression Analysis; Vascular Diseases; Vasodilation | 1999 |
Hyperhomocyst(e)inemia is associated with carotid atherosclerosis.
Topics: Age Factors; Body Mass Index; Carotid Artery Diseases; Carotid Artery, Common; Carotid Artery, Internal; Chromatography, High Pressure Liquid; Creatinine; Diabetes Complications; Female; Fluorescence; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Logistic Models; Male; Middle Aged; Regression Analysis; Risk Factors; Sex Factors; Smoking; Tunica Intima; Tunica Media; Ultrasonography; Vitamin B 12 | 1999 |
Extracellular magnesium regulates effects of vitamin B6, B12 and folate on homocysteinemia-induced depletion of intracellular free magnesium ions in canine cerebral vascular smooth muscle cells: possible relationship to [Ca2+]i, atherogenesis and stroke.
Topics: Animals; Arteriosclerosis; Basilar Artery; Calcium; Cells, Cultured; Cerebral Arteries; Dogs; Folic Acid; Homocysteine; Hyperhomocysteinemia; Magnesium; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Pyridoxine; Signal Transduction; Stroke; Vitamin B 12; Vitamins | 1999 |
The creative tension between the analyst and the clinician.
Topics: Cardiovascular Diseases; Chemistry, Analytic; Homocysteine; Humans; Hyperhomocysteinemia; Research | 1998 |
Key references: Homocysteine and atherothrombotic vascular disease.
Topics: Arteriosclerosis; Biomarkers; Embolism, Cholesterol; Homocysteine; Humans; Hyperhomocysteinemia; Vascular Diseases | 2000 |
Three months supplementation of hyperhomocysteinaemic patients with folic acid and vitamin B6 improves biological markers of endothelial dysfunction.
Topics: Adult; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pyridoxine; Risk Factors; Thrombomodulin; Vascular Diseases; von Willebrand Factor | 1999 |
[Hyperhomocysteinemia].
Topics: Colestipol; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Myocardial Infarction; Risk Factors | 1999 |
Effect of short-term vitamin (folic acid, vitamins B6 and B12) administration on endothelial dysfunction induced by post-methionine load hyperhomocysteinemia.
Topics: Administration, Oral; Adult; Blood Flow Velocity; Drug Therapy, Combination; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxine; Treatment Outcome; Vasodilation; Vitamin B 12 | 1999 |
An alternative view of homocysteine.
Topics: Arterial Occlusive Diseases; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Myocardial Infarction; Risk Factors | 1999 |
The 677T genotype of the common MTHFR thermolabile variant and fasting homocysteine in childhood venous thrombosis.
Topics: Adolescent; Age of Onset; Alleles; Case-Control Studies; Child; Child, Preschool; Factor V; Female; Genetic Predisposition to Disease; Genotype; Germany; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multifactorial Inheritance; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Prothrombin; Risk Factors; Statistics, Nonparametric; Venous Thrombosis | 1999 |
Effects of methionine-induced hyperhomocysteinemia on endothelium-dependent vasodilation and oxidative status in healthy adults.
Topics: Adult; Aged; Aging; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Oxidation-Reduction; Prospective Studies; Vasodilation | 2000 |
Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men.
Topics: Case-Control Studies; Coronary Disease; Europe; Fasting; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Risk Factors; United Kingdom; Vitamin B 12 | 2000 |
Low plasma folate in combination with the 677 C-->T methylenetetrahydrofolate reductase polymorphism is associated with increased risk of coronary artery disease in Koreans.
Topics: Adult; Aged; Asian People; Cardiac Catheterization; Coronary Disease; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Hyperhomocysteinemia; Korea; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors; Sex Factors; Vitamin B 12 | 2000 |
Plasma total homocysteine levels in subjects with hyperinsulinemia.
Topics: Adult; Aged; Blood Glucose; Coronary Disease; Cross-Sectional Studies; Female; Folic Acid; Glucose Tolerance Test; Homocysteine; Humans; Hyperhomocysteinemia; Hyperinsulinism; Insulin; Insulin Resistance; Life Style; Linear Models; Male; Middle Aged; Risk Factors | 2000 |
Cobalt-deficiency-induced hyperhomocysteinaemia and oxidative status of cattle.
Topics: Animals; Cattle; Cattle Diseases; Cobalt; Homocysteine; Hyperhomocysteinemia; Male; Oxidative Stress; Vitamin B 12 | 2000 |
Community-living nonagenarians in northern ireland have lower plasma homocysteine but similar methylenetetrahydrofolate reductase thermolabile genotype prevalence compared to 70-89-year-old subjects.
Topics: Age Distribution; Aged; Aged, 80 and over; Aging; Chromatography, Liquid; Cross-Sectional Studies; Female; Gene Expression; Genotype; Glomerular Filtration Rate; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Northern Ireland; Oxidoreductases Acting on CH-NH Group Donors; Population Surveillance; Prevalence; Vitamin B Complex | 2000 |
[Hyperhomocysteinemia and arterial or venous thrombosis. Retrospective study of 75 cases].
Topics: Adult; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Risk Factors; Thrombosis; Vitamin B 12 | 2000 |
Treatment with different doses of folic acid in haemodialysis patients: effects on folate distribution and aminothiol concentrations.
Topics: Biomarkers; Cysteine; Dose-Response Relationship, Drug; Erythrocytes; Female; Folic Acid; Glutathione; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Pteroylpolyglutamic Acids; Renal Dialysis; Renal Insufficiency; Treatment Outcome | 2000 |
Hyperhomocyst(e)inemia is a risk factor for arterial endothelial dysfunction in humans.
Topics: Aged; Arteries; Chromatography, High Pressure Liquid; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Risk Factors; Vascular Diseases | 2000 |
Hyperhomocyst(e)inemia and the increased risk of venous thromboembolism: more evidence from a case-control study.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Risk Factors; Thromboembolism | 2000 |
[Should we consider hyperhomocysteinemia as a vascular risk factor?].
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Polymorphism, Genetic; Risk Factors; Thrombosis; Vitamin B Complex | 2000 |
Plasma homocysteine levels in renal transplanted patients on cyclosporine or tacrolimus therapy: effect of treatment with folic acid.
Topics: Analysis of Variance; Case-Control Studies; Cholesterol; Creatinine; Cyclosporine; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Linear Models; Male; Middle Aged; Multivariate Analysis; Risk Factors; Tacrolimus; Triglycerides; Vitamin B 12 | 2000 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
The C677T methylenetetrahydrofolate reductase gene mutation in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Chi-Square Distribution; Cohort Studies; Deficiency Diseases; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Renal Dialysis; Risk Factors; Vascular Diseases | 2000 |
An increased serum level of free Apo(a) in renal patients is more striking than that of Lp(a) and is influenced by homocysteine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apolipoproteins A; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Linear Models; Lipoprotein(a); Male; Middle Aged; Nephrotic Syndrome; Peritoneal Dialysis; Renal Dialysis | 2000 |
Effect of chronic alcohol consumption on total plasma homocysteine level in rats.
Topics: Alcohol Drinking; Animals; Folic Acid; Hematinics; Homocysteine; Hyperhomocysteinemia; Male; Pyridoxine; Rats; Rats, Sprague-Dawley; Vitamin B 12 | 2000 |
Interrelations between plasma homocysteine and intracellular S-adenosylhomocysteine.
Topics: Adult; Aged; Animals; Case-Control Studies; Chromatography, High Pressure Liquid; Erythrocytes; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Tissue Distribution; Vascular Diseases | 2000 |
The role of vitamin B12 in fasting hyperhomocysteinemia and its interaction with the homozygous C677T mutation of the methylenetetrahydrofolate reductase (MTHFR) gene. A case-control study of patients with early-onset thrombotic events.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Age of Onset; Aged; Amino Acid Substitution; Case-Control Studies; Fasting; Female; Folic Acid; Gene Frequency; Genetic Heterogeneity; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors; Sex Factors; Tetrahydrofolates; Thrombophilia; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Hyperhomocysteinaemia is not associated with isolated crural arterial occlusive disease: The Hoorn Study.
Topics: Aged; Arterial Occlusive Diseases; Blood Flow Velocity; Cross-Sectional Studies; Female; Glucose Tolerance Test; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Leg; Male; Middle Aged | 2000 |
High prevalence of hyperhomocysteinemia in critically ill patients.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; APACHE; Base Sequence; Critical Illness; DNA Primers; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Molecular Sequence Data; Oxidoreductases; Polymorphism, Restriction Fragment Length; Prevalence; Prospective Studies; Survivors | 2000 |
Hyperhomocysteinemia: a risk factor for central retinal vein occlusion.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Prognosis; Retinal Vein Occlusion; Risk Factors | 2000 |
Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in monkeys with hyperhomocyst(e)inemia or hypercholesterolemia.
Topics: Animals; Arginine; Cell Line, Transformed; Cholesterol; Diet; Dietary Fats; Endothelium, Vascular; Enzyme Inhibitors; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Macaca fascicularis; Methionine; Nitric Oxide Synthase; Regression Analysis; Vasodilation | 2000 |
Enhancement by homocysteine of plasminogen activator inhibitor-1 gene expression and secretion from vascular endothelial and smooth muscle cells.
Topics: Arteriosclerosis; Cells, Cultured; Endothelium, Vascular; Gene Expression; Homocysteine; Humans; Hyperhomocysteinemia; Muscle, Smooth, Vascular; Plasminogen Activator Inhibitor 1; RNA, Messenger; Thrombosis; Tissue Plasminogen Activator; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2000 |
Homocysteine and heart disease in Indian Asians.
Topics: Coronary Disease; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; India; Risk Factors; United Kingdom; Vitamin B 12 | 2000 |
Homocysteine and heart disease in Indian Asians.
Topics: Coronary Disease; Folic Acid; Folic Acid Deficiency; Fructose; Homocysteine; Humans; Hyperhomocysteinemia; India; Malabsorption Syndromes; United Kingdom; Vitamin B 12 | 2000 |
Tissue factor and homocysteine levels in ischemic heart disease are associated with angiographically documented clinical recurrences after coronary angioplasty.
Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Antithrombin III; Coronary Angiography; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Middle Aged; Myocardial Ischemia; Peptide Hydrolases; Recurrence; Risk Factors; Thrombophilia; Thromboplastin; Vitamins | 2000 |
Elevated circulating homocyst(e)ine levels in placental vascular disease and associated pre-eclampsia.
Topics: Adult; Biomarkers; Birth Weight; Female; Fetal Growth Retardation; Homocysteine; Humans; Hyperhomocysteinemia; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Ultrasonography, Prenatal; Vascular Diseases | 2000 |
Hyperhomocystinemia in patients with nonarteritic anterior ischemic optic neuropathy, central retinal artery occlusion, and central retinal vein occlusion.
Topics: Aged; Arteritis; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Optic Neuropathy, Ischemic; Prevalence; Retinal Artery Occlusion; Retinal Vein Occlusion; Retrospective Studies; Risk Factors | 2000 |
Homocysteine and cardiovascular risk.
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Risk Factors | 2000 |
Homocysteine: to screen and treat or to wait and see?
Topics: Dietary Supplements; Female; Health Policy; Heart Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mass Screening; Risk Factors; Sex Factors; Vitamins | 2000 |
Homocysteine as a risk factor for restenosis after coronary angioplasty.
Topics: Aged; Angioplasty, Balloon, Coronary; Comorbidity; Coronary Angiography; Coronary Disease; Diabetes Mellitus; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Male; Middle Aged; Obesity; Recurrence; Risk Factors; Sensitivity and Specificity; Smoking | 2000 |
The effect of different treatment regimens in reducing fasting and postmethionine-load homocysteine concentrations.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pyridoxine; Risk Factors | 2000 |
Homocysteine: more questions than answers.
Topics: Dietary Supplements; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vascular Diseases; Vitamins | 2000 |
Hyperhomocysteinemia in liver transplant recipients: prevalence and multivariate analysis of predisposing factors.
Topics: Creatinine; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Liver Transplantation; Male; Middle Aged; Multivariate Analysis; Postoperative Complications; Prevalence; Risk Factors; Treatment Outcome | 2000 |
Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Folic Acid; Food, Formulated; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Thrombomodulin; Vasodilator Agents | 2000 |
The (non-)sense of the methionine loading test for detecting hyperhomocysteinaemia.
Topics: Cardiovascular Diseases; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Methionine | 2000 |
Homocysteine inhibits retinoic acid synthesis: a mechanism for homocysteine-induced congenital defects.
Topics: Abnormalities, Drug-Induced; Animals; Biological Transport, Active; Cell Line; Chick Embryo; Genes, Reporter; Homocysteine; Hyperhomocysteinemia; Lac Operon; Receptors, Retinoic Acid; Signal Transduction; Transfection; Tretinoin | 2000 |
Homocysteine elevation in sickle cell disease.
Topics: Adolescent; Adult; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Hemoglobin SC Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Requirements; Pilot Projects; Vitamin B 12 | 2000 |
[Homocysteine and its metabolites in chronic renal insufficiency and the effect of a vitamin replacement].
Topics: Adult; Aged; Arteriosclerosis; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Middle Aged; Pyridoxine; Renal Dialysis; Severity of Illness Index; Vitamin B 12; Vitamin B Complex | 2000 |
Markers of thrombophilia in retinal vein thrombosis.
Topics: Adult; Aged; Antithrombins; Biomarkers; Factor V; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Protein C; Protein S; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Thromboembolism; Thrombophilia | 2000 |
[The mechanisms of hyperhomocysteinemia in coronary heart disease].
Topics: Adult; Aged; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Risk Factors | 1998 |
The effect of C677T mutation of methylene tetrahydrofolate reductase gene and plasma folate level on hyperhomocysteinemia in patients with meningomyelocele.
Topics: Alleles; Asian People; Child; Female; Folic Acid; Gene Expression; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Meningomyelocele; Methylenetetrahydrofolate Dehydrogenase (NADP); Point Mutation; Polymerase Chain Reaction | 2000 |
Determinants of plasma total homocysteine levels in Korean chronic renal transplant recipients.
Topics: Adult; Aged; Cardiovascular Diseases; Creatinine; Cross-Sectional Studies; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Korea; Male; Middle Aged; Prevalence; Pyridoxal Phosphate; Serum Albumin; Vitamin B 12 | 2000 |
Homocysteine & heart disease.
Topics: Cardiovascular Diseases; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2000 |
Circadian rhythm of serum total homocysteine in men.
Topics: Adult; Aged; Arteriosclerosis; Case-Control Studies; Circadian Rhythm; Diabetes Complications; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reference Values; Risk Factors; Severity of Illness Index; Time Factors | 2000 |
Correlation of homocytsteine levels with the extent of coronary atherosclerosis in patients with low cardiovascular risk profiles.
Topics: Coronary Angiography; Coronary Artery Disease; Diabetes Complications; Female; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Hypertension; Linear Models; Male; Middle Aged; Risk Factors; Severity of Illness Index; Smoking | 2000 |
Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia.
Topics: Aged; Alleles; Alternative Splicing; Animals; Antigens, Surface; Carboxypeptidases; Cloning, Molecular; COS Cells; DNA Mutational Analysis; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Hyperhomocysteinemia; Intestinal Absorption; Isoenzymes; Jejunum; Middle Aged; Molecular Sequence Data; Polymorphism, Genetic; RNA, Messenger; Sequence Analysis, DNA; Transfection; White People | 2000 |
Vitamin B-12 deficiency and hyperhomocysteinemia are partly ameliorated by cobalt and nickel supplementation in pigs.
Topics: Animal Feed; Animals; Cobalt; Copper; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Homocysteine; Hyperhomocysteinemia; Iron; Liver; Male; Nickel; Swine; Trace Elements; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Serum total homocysteine concentration is related to self-reported heart attack or stroke history among men and women in the NHANES III.
Topics: Adult; Age Factors; Aged; Female; Folic Acid; Heart Arrest; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutrition Surveys; Risk Factors; Self Disclosure; Sex Factors; Stroke; Vitamin B 12 | 2000 |
Role of aminothiols as a component of the plasma antioxidant system and relevance to homocysteine-mediated vascular disease.
Topics: Adolescent; Adult; Aged; Antioxidants; Child; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Risk Factors; Vascular Diseases | 2001 |
Blood homocysteine and vitamin B levels are not associated with cognitive skills in healthy normally ageing subjects.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cognition; Dementia; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B 12 | 2000 |
Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia.
Topics: Angiography; Animals; Arginine; Blood Pressure; Body Weight; Collateral Circulation; Cyclic GMP; Disease Models, Animal; Heart Rate; Hindlimb; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Muscle, Skeletal; Neovascularization, Physiologic; Nitrates; Nitrites; Rats; Regional Blood Flow; Time Factors | 2000 |
Hyperhomocysteinemia in renal transplant recipients with cyclosporine.
Topics: Cyclosporine; Erythrocytes; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Reference Values; Vitamin B 12 | 2000 |
Hyperhomocysteinemia in type 2 diabetes: relationship to macroangiopathy, nephropathy, and insulin resistance.
Topics: Aged; Cohort Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Logistic Models; Male; Metabolic Clearance Rate; Metformin; Middle Aged; Vitamin B 12 | 2000 |
Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury.
Topics: Administration, Oral; Angioplasty, Balloon; Animals; Carotid Arteries; Carotid Artery Diseases; Cystine; Diet; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Male; Methionine; Rats; Rats, Sprague-Dawley; Tunica Intima; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Melatonin counteracts potentiation by homocysteine of KCL-induced vasoconstriction in human umbilical artery: relation to calcium influx.
Topics: Antioxidants; Calcium Signaling; Cardiovascular Diseases; Drug Interactions; Female; Free Radical Scavengers; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Mannitol; Melatonin; Potassium Chloride; Pregnancy; Umbilical Arteries; Vasoconstriction | 2001 |
Homocysteine and the MTHFR 677C-->T allele in premature coronary artery disease. Case control and family studies.
Topics: Adult; Age of Onset; Case-Control Studies; Coronary Disease; Family Health; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors | 2001 |
Is there a role of cyclosporine A on total homocysteine export from human renal proximal tubular epithelial cells?
Topics: Biological Transport, Active; Cells, Cultured; Cyclosporine; Epithelial Cells; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubules, Proximal; Methionine; Pyridoxine; Vitamin B 12 | 2001 |
Homocysteine, its metabolites, and B-group vitamins in renal transplant patients.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Risk Factors; Vitamin B Complex | 2001 |
Elevation of asymmetrical dimethylarginine may mediate endothelial dysfunction during experimental hyperhomocyst(e)inaemia in humans.
Topics: Acute Disease; Adult; Arginine; Brachial Artery; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Nitroglycerin; Vasodilation; Vasodilator Agents | 2001 |
5,10-methylenetetrahydrofolate reductase common mutations, folate status and plasma homocysteine in healthy French adults of the Supplementation en Vitamines et Mineraux Antioxydants (SU.VI.MAX) cohort.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Cohort Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Oxidoreductases; Polymorphism, Genetic; Sex Factors | 2000 |
Clinical relevance of the methionine loading test for assessment of hyperhomocysteinaemia.
Topics: Cardiovascular Diseases; Fasting; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Methionine; Risk Factors | 2000 |
Hyperhomocysteinemia: a new risk factor for central retinal vein occlusion.
Topics: Adult; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Male; Middle Aged; Reference Values; Retinal Vein Occlusion; Retinal Vessels; Risk Factors; Vision Disorders; Visual Acuity | 2000 |
Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers.
Topics: Animals; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Lipid Peroxides; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2001 |
Effects of methionine loading on plasma and erythrocyte sulphur amino acids and sulph-hydryls before and after co-factor supplementation in haemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids, Sulfur; Case-Control Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxine; Renal Dialysis; Sulfhydryl Compounds | 2001 |
Hyperhomocysteinemia and hypercholesterolemia associated with hypothyroidism in the third US National Health and Nutrition Examination Survey.
Topics: Adult; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Health Surveys; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Hypothyroidism; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Regression Analysis; Thyrotropin; Triglycerides; United States | 2001 |
Plasma folate, vitamin B(12), and homocyst(e)ine concentrations in preeclamptic and normotensive Peruvian women.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Odds Ratio; Peru; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Surveys and Questionnaires; Vitamin B 12 | 2001 |
Unsuspected hyperhomocysteinemia in chronically anticoagulated patients.
Topics: Aged; Anticoagulants; Case-Control Studies; Chronic Disease; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vegetables; Vitamin K | 2001 |
Hyperhomocysteinemia and restenosis.
Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Odds Ratio; Recurrence; Risk Factors; Stents | 2001 |
Lifestyle effects on homocysteine and an alcohol paradox.
Topics: Aged; Aging; Alcohol Drinking; Animals; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male | 2001 |
Mild hyperhomocyst(e)inemia: a possible risk factor for cervical artery dissection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Carotid Artery, Internal, Dissection; Comorbidity; Disease Susceptibility; Female; Folic Acid; Genotype; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Vertebral Artery Dissection; Vitamin B 12 | 2001 |
Hyperhomocysteinemia: a risk factor for central retinal vein occlusion.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Retinal Vein Occlusion; Risk Factors; Vision Disorders | 2001 |
A new HPLC micromethod to measure total plasma homocysteine in newborn.
Topics: Avitaminosis; Chromatography, High Pressure Liquid; Female; Fluorescent Dyes; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Male; Neonatal Screening; Oxadiazoles; Reproducibility of Results | 2001 |
Hyperhomocysteinemia in Greek patients with inflammatory bowel disease.
Topics: Adult; Aged; Colitis, Ulcerative; Crohn Disease; Female; Folic Acid; Greece; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Thrombosis | 2000 |
Homocysteine-associated acute mesenteric artery occlusion treated with thrombectomy and bowel resection.
Topics: Anastomosis, Surgical; Homocysteine; Humans; Hyperhomocysteinemia; Ileum; Ischemia; Magnetic Resonance Angiography; Male; Mesenteric Artery, Superior; Mesenteric Vascular Occlusion; Middle Aged; Thrombectomy; Thrombosis | 2001 |
Effect of supplemental methionine on plasma homocysteine concentrations in healthy men: a preliminary study.
Topics: Adult; Cardiovascular Diseases; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Risk Factors | 2001 |
Anti-epileptic drug treatment in children: hyperhomocysteinaemia, B-vitamins and the 677C-->T mutation of the methylenetetrahydrofolate reductase gene.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Valproic Acid | 2000 |
Racial variation in fasting and random homocysteine levels.
Topics: Black People; Blood Urea Nitrogen; Body Mass Index; Creatinine; Fasting; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; New York City; Personnel, Hospital; Random Allocation; Reference Values; Time Factors; Vitamin B 12; White People | 2001 |
[Clinical significance of homocysteine].
Topics: Homocysteine; Humans; Hyperhomocysteinemia | 2001 |
Decreased smooth muscle cell/extracellular matrix ratio of media of femoral artery in patients with atherosclerosis and hyperhomocysteinemia.
Topics: Adult; Aged; Biopsy; Cardiovascular Diseases; Comorbidity; Endothelium, Vascular; Extracellular Matrix; Female; Femoral Artery; Homocysteine; Humans; Hyperhomocysteinemia; Immunohistochemistry; Male; Middle Aged; Muscle, Smooth, Vascular; Peripheral Vascular Diseases; Risk Factors | 2001 |
Vitamin B12 deficiency, infertility and recurrent fetal loss.
Topics: Abortion, Habitual; Adult; Anemia, Megaloblastic; Blood Coagulation Disorders; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infertility, Female; Vitamin B 12 Deficiency | 2001 |
Oxidative stress and homocysteine in coronary artery disease.
Topics: Angina Pectoris; Angina, Unstable; Chronic Disease; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Male; Malondialdehyde; Middle Aged; Oxidative Stress | 2001 |
Hyperhomocysteinemia associated with poor recall in the third National Health and Nutrition Examination Survey.
Topics: Age Factors; Aged; Blood Pressure; Erythrocytes; Ethnicity; Female; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Memory, Short-Term; Mental Status Schedule; Middle Aged; Multivariate Analysis; Racial Groups; Sex Factors; Smoking; Socioeconomic Factors; United States | 2001 |
Hyperhomocysteinemia and cardiovascular disease.
Topics: Arteriosclerosis; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases | 2001 |
Homocysteine, vitamin B12, serum and erythrocyte folate in peritoneal dialysis patients.
Topics: Aged; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Peritoneal Dialysis; Vitamin B 12 | 2001 |
Hyperhomocysteinemia in myelodysplastic syndromes: specific association with autoimmunity and cardiovascular disease.
Topics: Analysis of Variance; Autoimmunity; Cardiovascular Diseases; Case-Control Studies; Fasting; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Malondialdehyde; Myelodysplastic Syndromes; Oxidative Stress | 2001 |
Renal insufficiency, vitamin B(12) status, and population attributable risk for mild hyperhomocysteinemia among coronary artery disease patients in the era of folic acid-fortified cereal grain flour.
Topics: Adult; Aged; Coronary Artery Disease; Coronary Disease; Creatinine; Edible Grain; Female; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vitamin B 12 | 2001 |
Influence of vitamin-optimized plasma homocysteine cutoff values on the prevalence of hyperhomocysteinemia in healthy adults.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Pyridoxine; Vitamin B 12; Vitamins | 2001 |
Hyperhomocysteinemia and function of the endoplasmic reticulum.
Topics: Cholesterol; Endoplasmic Reticulum; Homocysteine; Hyperhomocysteinemia; Lipid Metabolism; Protein Denaturation | 2001 |
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways.
Topics: Animals; Arteriosclerosis; Carrier Proteins; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Cholesterol; Cystathionine beta-Synthase; DNA-Binding Proteins; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Fatty Liver; Heat-Shock Proteins; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, VLDL; Liver; Mice; Molecular Chaperones; Protein Denaturation; Sterol Regulatory Element Binding Protein 1; Transcription Factors; Triglycerides | 2001 |
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Betaine; Betaine-Homocysteine S-Methyltransferase; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methyltransferases; Middle Aged; Peritoneal Dialysis; Predictive Value of Tests; Pyridoxine; Renal Dialysis; Sarcosine; Uremia; Vitamin B 12; Zinc | 2001 |
Plasma proteins containing damaged L-isoaspartyl residues are increased in uremia: implications for mechanism.
Topics: Aspartic Acid; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Renal Dialysis; S-Adenosylhomocysteine; Serum Albumin; Uremia | 2001 |
The 1298A-->C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine.
Topics: Blotting, Western; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Culture Techniques; DNA, Complementary; Gene Expression; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Probability; Sensitivity and Specificity | 2001 |
Importance of hyperhomocysteinemia as a risk factor for venous thromboembolism in a Taiwanese population. A case-control study.
Topics: Adult; Aged; Case-Control Studies; Factor V; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Risk Factors; Taiwan; Thromboembolism; Thrombophilia; Venous Thrombosis | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
Screening for hyperhomocysteinemia in young adults with premature coronary artery disease.
Topics: Age of Onset; Chromatography, High Pressure Liquid; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors | 1999 |
Homocysteine augments cytokine-induced chemokine expression in human vascular smooth muscle cells: implications for atherogenesis.
Topics: Arteriosclerosis; Cells, Cultured; Chemokine CCL2; Chemokines; Cytokines; Drug Synergism; Homocysteine; Humans; Hyperhomocysteinemia; Interferon-gamma; Interleukin-1; Interleukin-8; Muscle, Smooth, Vascular; NF-kappa B; Risk Factors; RNA, Messenger; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Up-Regulation | 2001 |
Femoral head necrosis and hyperhomocysteinemia.
Topics: Female; Femur Head Necrosis; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged | 2001 |
Relationship between plasma homocysteine and vitamin status in the Framingham study population. Impact of folic acid fortification.
Topics: Aged; Aged, 80 and over; Carotid Stenosis; Cohort Studies; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Odds Ratio; Risk; United States; Vitamin B Complex | 2000 |
Correlation between Helicobacter pylori infection, gastric inflammation and serum homocysteine concentration.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Ischemia; Sex Factors; Smoking | 2001 |
Hyperhomocysteinemia: another independent vascular risk factor.
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Research Design; Risk Factors; Saudi Arabia | 2000 |
Hyperhomocysteinaemia in Behçet's disease.
Topics: Adult; Behcet Syndrome; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Thrombosis | 2001 |
Cystatin C is an independent predictor of fasting and post-methionine load total homocysteine concentrations among stable renal transplant recipients.
Topics: Adult; Aged; Biomarkers; Cystatin C; Cystatins; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Methionine; Middle Aged; Regression Analysis | 2001 |
Hyperhomocystinemia: a risk factor or a consequence of coronary heart disease?
Topics: Case-Control Studies; Cholesterol; Confounding Factors, Epidemiologic; Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires | 2001 |
Regarding "high prevalence of mild hyperhomocysteinemia in patients with abdominal aortic aneurysm".
Topics: Aortic Aneurysm, Abdominal; Homocysteine; Humans; Hyperhomocysteinemia; Thrombomodulin | 2001 |
Lifestyle factors and plasma homocysteine concentrations in a general population sample.
Topics: Adult; Aged; Alcohol Drinking; Analysis of Variance; Coffee; Cross-Sectional Studies; Diet; Diet Surveys; Exercise; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Linear Models; Male; Middle Aged; Netherlands; Sampling Studies; Smoking; Surveys and Questionnaires; Vitamin B Complex | 2001 |
Hyperhomocysteinemia in dementia.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Pilot Projects; Reference Values; Regression Analysis; Risk Factors; Vitamin B 12 | 2000 |
Homozygous VN (677C to T) and d/D (2756G to A) variants in the methylenetetrahydrofolate and methionine synthase genes in a case of hyperhomocysteinemia with stroke at young age.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; DNA; DNA Restriction Enzymes; Family Health; Female; Genetic Variation; Genotype; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Polymorphism, Genetic; Stroke; Tetrahydrofolates | 2001 |
Serum cystatin C is an independent predictor of total homocysteine levels in stable Korean renal transplant recipients with normal serum creatinine.
Topics: Adult; Aged; Biomarkers; Creatinine; Cross-Sectional Studies; Cystatin C; Cystatins; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Korea; Male; Middle Aged; Regression Analysis | 2001 |
Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study.
Topics: Adult; Cohort Studies; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Models, Chemical; Prevalence; Risk Factors; Vitamin B 12 | 2001 |
Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylmalonic Acid; Middle Aged; Prevalence; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Mild hyperhomocysteinemia: vitamin supplementation or not?
Topics: Adult; Case-Control Studies; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Mutation; Polymorphism, Genetic; Vascular Diseases; Vitamins | 2001 |
The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations.
Topics: Adult; Ferredoxin-NADP Reductase; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osmolar Concentration; Polymorphism, Genetic | 2001 |
Hyperhomocysteinemia in renal transplant recipients.
Topics: Blood Glucose; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Lipids; Male; Reference Values | 2001 |
Comparison of three methods for total homocysteine plasma determination.
Topics: Bias; Chromatography, High Pressure Liquid; Clinical Laboratory Techniques; Enzyme-Linked Immunosorbent Assay; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Hyperhomocysteinemia; Male; Reference Standards; Reproducibility of Results | 2001 |
Elevated plasma homocysteine concentrations six months after gastroplasty in morbidly obese subjects.
Topics: Adult; Blood Glucose; China; Cholesterol, HDL; Female; Gastroplasty; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Male; Obesity, Morbid; Time Factors; Triglycerides | 2001 |
Hydrocephalus internus in two patients with 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Cerebral Ventricles; Demyelinating Diseases; Female; Homocysteine; Humans; Hydrocephalus; Hyperhomocysteinemia; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases | 2000 |
[Plasma homocysteine levels in patients with ischemic heart disease].
Topics: Aged; Drug Administration Schedule; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Ischemia; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Hyperhomocysteinemia, diabetes mellitus, and carotid atherosclerosis independently increase atherosclerotic vascular disease outcome in Japanese patients with end-stage renal disease.
Topics: Adult; Aged; Arteriosclerosis; Carotid Arteries; Carotid Artery Diseases; Case-Control Studies; Diabetes Complications; Female; Follow-Up Studies; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Outcome Assessment, Health Care; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Risk Factors; Ultrasonography | 2001 |
The effect of polymorphisms of MTHER gene and vitamin B on hyperhomocysteinemia.
Topics: Aged; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Restriction Fragment Length; Vitamin B 12 | 2001 |
Does homocysteine promote atherosclerosis?
Topics: Animals; Arteriosclerosis; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Mice; Risk Factors | 2001 |
Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice.
Topics: Animals; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Collagen; Coronary Artery Disease; Dietary Supplements; Female; Homocysteine; Hyperhomocysteinemia; Lipids; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Thrombosis | 2001 |
Hyperhomocysteinemia and prevalence of polymorphisms of homocysteine metabolism-related enzymes in patients with inflammatory bowel disease.
Topics: Adult; Aged; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Middle Aged; Polymorphism, Genetic; Prevalence | 2001 |
Is hyperhomocysteinemia due to the oxidative depletion of folate rather than to insufficient dietary intake?
Topics: Dementia, Vascular; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Models, Chemical; Neopterin; Oxidative Stress; Oxygen; Vascular Diseases; Vitamin B 12 | 2001 |
Hyperhomocysteinemia in advanced age.
Topics: Aged; Aging; Chronic Disease; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Time Factors; Vitamin B 6 | 2001 |
Genetic defects as important factors for moderate hyperhomocysteinemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Age Factors; Aged; Aged, 80 and over; Cystathionine; DNA Mutational Analysis; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Hyperhomocysteinemia and hyperlipidemia in coronary heart disease.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Aged; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases; Point Mutation; Risk Factors; Vitamin B 12 | 1999 |
Antiepileptic drugs as independent predictors of plasma total homocysteine levels.
Topics: Adult; Amino Acid Substitution; Anticonvulsants; Cholesterol; Cholesterol, HDL; Confidence Intervals; Cysteine; Epilepsy; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mutation; Predictive Value of Tests; Prevalence; Statistics, Nonparametric; Threonine; Triglycerides; Vitamin B 12 | 2001 |
Mild hyperhomocysteinemia is not associated with cardiac allograft coronary disease.
Topics: Adult; Aged; Coronary Angiography; Coronary Disease; Creatinine; Cross-Sectional Studies; Female; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Vitamin B 12; Vitamin B 6 | 2001 |
Hyperhomocysteinemia and transplant coronary artery disease in cardiac transplant recipients.
Topics: Adult; Coronary Angiography; Coronary Disease; Female; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged | 2001 |
Plasma homocysteine level in relation to folate and vitamin B6 status in apparently normal men.
Topics: Adult; Body Mass Index; Diet, Vegetarian; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Vitamin B 6; Vitamin B 6 Deficiency | 2001 |
Hyperhomocysteinemia in liver cirrhosis: mechanisms and role in vascular and hepatic fibrosis.
Topics: Arteriosclerosis; Cells, Cultured; Female; Fibrosis; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Liver Cirrhosis; Male; Methionine; Middle Aged; Models, Chemical; Muscle, Smooth, Vascular; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2001 |
Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine.
Topics: Amidohydrolases; Animals; Aorta; Arginine; Arteriosclerosis; Cattle; Cell Line; Culture Techniques; Endothelium, Vascular; Homocysteine; Hydrolases; Hyperhomocysteinemia; Kinetics; Methionine; Nitric Oxide; Nitric Oxide Synthase; Recombinant Fusion Proteins; Signal Transduction | 2001 |
[Genetic polymorphisms of homocysteine metabolism related enzymes in patients with coronary heart disease].
Topics: Adult; Coronary Disease; Cystathionine beta-Synthase; Female; Gene Frequency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length | 1999 |
Is hyperhomocysteinemia a risk factor or a consequence of coronary heart disease?
Topics: Coronary Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2001 |
Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine.
Topics: Activating Transcription Factor 3; Apoptosis; Cells, Cultured; Endoplasmic Reticulum; Endoribonucleases; Endothelium, Vascular; Enzyme Activation; Homocysteine; Humans; Hyperhomocysteinemia; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Protein Serine-Threonine Kinases; Proteins; Repressor Proteins; TNF Receptor-Associated Factor 2; Transcription Factors; Transcriptional Activation; Umbilical Veins | 2001 |
Hyperhomocysteinemia and related factors in 600 hospitalized elderly subjects.
Topics: Aged; Aged, 80 and over; Aging; Dementia; Diabetes Complications; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Kinetics; Linear Models; Male; Methionine; Nutrition Disorders; Odds Ratio; Renal Insufficiency; Vascular Diseases | 2001 |
Total homocysteine is making its way into pediatric laboratory diagnostics.
Topics: Adult; Avitaminosis; Child; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylmalonic Acid; Pediatrics; Pregnancy; Vitamin B 12 | 2001 |
Hyperhomocysteinaemia and folate deficiency in human immunodeficiency virus-infected children.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Female; Folic Acid Deficiency; HIV Infections; HIV-1; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Male; Methionine; Statistics as Topic; Vitamin B 12 | 2001 |
Interplay between methylenetetrahydrofolate reductase gene polymorphism 677C-->T and serum folate levels in determining hyperhomocysteinemia in heart transplant recipients.
Topics: Adult; Aged; Coronary Artery Disease; Female; Folic Acid; Genotype; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Postoperative Complications; Prognosis; Risk Factors | 2001 |
Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia, and cardiovascular diseases in chronic hemodialysis patients.
Topics: Adult; Aged; Cardiovascular Diseases; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidoreductases Acting on CH-NH Group Donors; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renal Dialysis; Risk Factors; Statistics as Topic; Vitamin B 12 | 2002 |
Plasma homocysteine concentrations in patients with liver cirrhosis.
Topics: Age Factors; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis; Male; Middle Aged; Multivariate Analysis; Sex Factors | 2002 |
Hyperhomocysteinemia in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Topics: Adult; Age Distribution; Biopsy; Case-Control Studies; Cerebral Arterial Diseases; Dementia, Multi-Infarct; Dementia, Vascular; DNA Mutational Analysis; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenotype; Risk Factors; Sex Distribution | 2001 |
Is homocysteine a pro-oxidant?
Topics: Animals; Arteriosclerosis; Homocysteine; Humans; Hydrogen Peroxide; Hyperhomocysteinemia; In Vitro Techniques; Kinetics; Luminescent Measurements; Metmyoglobin; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Thrombosis | 2001 |
Hyperhomocysteinemia and other inherited prothrombotic conditions in young adults with a history of ischemic stroke.
Topics: Adult; Brain Ischemia; Factor V; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prothrombin; Risk Factors; Stroke; Venous Thrombosis | 2002 |
Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice.
Topics: Animals; Bradykinin; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Liver; Mesentery; Methacholine Chloride; Mice; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Vasodilation | 2002 |
The T allele of the C(677)T 5,10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism may protect endothelial function in young, normal subjects.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Acetylcholine; Alleles; Cross-Sectional Studies; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nitroprusside; Oxidoreductases; Plethysmography; Polymorphism, Genetic; Vasodilation | 2002 |
Diet-induced mild hyperhomocysteinemia and increased salt intake diminish vascular endothelial function in a synergistic manner.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Carotid Artery, Common; Drug Synergism; Endothelium, Vascular; Folic Acid; Heart Rate; Homocysteine; Hyperhomocysteinemia; Japan; Kidney; Lipid Peroxidation; Lipids; Male; Methionine; Natriuresis; Nitrites; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sodium Chloride, Dietary | 2002 |
The relation between plasma homocysteine concentration and methylenetetrahydrofolate reductase gene polymorphism in pregnant women.
Topics: Adult; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, First | 2001 |
Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biomarkers; Brain; Cell Survival; Corpus Striatum; Diet; Dopamine; Drug Synergism; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Mice; Mice, Inbred C57BL; Mitochondria; Motor Activity; Neurons; Oxidative Stress; Parkinson Disease; Parkinson Disease, Secondary; Rotenone; Tumor Cells, Cultured | 2002 |
Determination of total homocysteine in plasma: comparison of the Abbott IMx immunoassay with high performance liquid chromatography.
Topics: Adult; Chromatography, High Pressure Liquid; False Negative Reactions; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Male; Methionine; Middle Aged; Photochemistry; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity; Thrombophilia; Thrombosis | 2002 |
Neointimal hyperplasia in balloon-injured rat carotid arteries: the influence of hyperhomocysteinemia.
Topics: Animals; Carotid Artery Injuries; Carotid Artery, Common; Catheterization; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Hyperplasia; Image Processing, Computer-Assisted; Male; Rats; Rats, Inbred Lew; Time Factors; Tunica Intima | 2002 |
Plasma homocysteine levels in Taiwanese vegetarians are higher than those of omnivores.
Topics: Adult; Amino Acids; Cardiovascular Diseases; Diet, Vegetarian; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Nutritional Status; Regression Analysis; Risk Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2002 |
The Chilean flour folic acid fortification program reduces serum homocysteine levels and masks vitamin B-12 deficiency in elderly people.
Topics: Aged; Cardiovascular Diseases; Chile; Cholesterol, HDL; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutritional Status; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Homocysteine: a risk factor for retinal venous occlusive disease.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Diabetes Mellitus; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retinal Vein Occlusion; Risk Factors | 2002 |
Effect of homocysteine on the L-arginine/nitric oxide synthase/nitric oxide pathway in human platelets.
Topics: Adult; Arginine; Biomarkers; Blood Platelets; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nitric Oxide; Nitric Oxide Synthase; Risk Factors | 2002 |
Homocysteine levels are increased due to lack of melatonin in pinealectomized rats: is there a link between melatonin and homocysteine?
Topics: Animals; Homocysteine; Hyperhomocysteinemia; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar | 2002 |
Homocysteine and dementias.
Topics: Alzheimer Disease; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2002 |
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Confounding Factors, Epidemiologic; Dementia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Multivariate Analysis; Proportional Hazards Models; Risk Factors | 2002 |
Evaluation of an enzymatic method to measure total homocysteine in plasma.
Topics: Blood Preservation; Chromatography, High Pressure Liquid; Cryopreservation; Fasting; Homocysteine; Humans; Hydrogen Sulfide; Hydrolases; Hyperhomocysteinemia; Plasma; Recombinant Proteins; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Hyperhomocysteinemia predicts cardiovascular outcomes in hemodialysis patients.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Renal Dialysis; Risk Factors | 2002 |
Micro- and macrovascular complications and hyperhomocysteinaemia in type 1 diabetic patients.
Topics: Adult; Aging; Blood Pressure; Cholesterol; Cholesterol, HDL; Creatinine; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Retinopathy; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Time Factors | 2001 |
Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke.
Topics: Adult; Amino Acid Substitution; Brain Ischemia; Carotid Artery, Internal, Dissection; Case-Control Studies; Comorbidity; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Prospective Studies; Reference Values; Risk Factors; Stroke; Vertebral Artery Dissection | 2002 |
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Cells, Cultured; Diet; Disease Models, Animal; DNA Damage; DNA Repair; Folic Acid Deficiency; Hippocampus; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Transgenic; Neurons; Rats; Uracil | 2002 |
Leukocytes extravasation in acute homocysteinemic rats.
Topics: Acute Disease; Animals; Cell Adhesion; Endothelium, Vascular; Hemodynamics; Homocysteine; Hyperhomocysteinemia; Leukocytes; Male; Rats; Rats, Sprague-Dawley | 2002 |
Implications of hyperhomocysteinemia in glomerular sclerosis in hypertension.
Topics: Animals; Chromatography, High Pressure Liquid; Diet; Disease Models, Animal; Glomerular Mesangium; Homocysteine; Hyperhomocysteinemia; Hypertension; Methionine; Rats; Rats, Sprague-Dawley; Salts; Sclerosis | 2002 |
[Evolution of homocysteine during ovarian stimulation for IVF or ICSI].
Topics: Adult; Chorionic Gonadotropin; Female; Fertilization in Vitro; Gonadotropin-Releasing Hormone; Homocysteine; Humans; Hyperhomocysteinemia; Ovulation Induction; Sperm Injections, Intracytoplasmic | 2002 |
Hyperhomocysteinemia is common in patients with antiphospholipid syndrome and may contribute to expression of major thrombotic events.
Topics: Abortion, Habitual; Adult; Aged; Antiphospholipid Syndrome; Chi-Square Distribution; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pregnancy; Risk; Thromboembolism | 2002 |
Homocysteine and atheromatous renal artery stenosis.
Topics: Aged; Alleles; Arteriosclerosis; Case-Control Studies; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Artery Obstruction; Risk Factors; Vitamin B 12 | 2001 |
Oxidant stress mechanism of homocysteine potentiating Con A-induced proliferation in murine splenic T lymphocytes.
Topics: Animals; Antioxidants; Apolipoproteins E; Apoptosis; Cell Division; Cells, Cultured; Concanavalin A; Dose-Response Relationship, Immunologic; Homocysteine; Hyperhomocysteinemia; Interleukin-2; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidative Stress; Reactive Oxygen Species; Spleen; Sulfhydryl Compounds; T-Lymphocytes | 2002 |
Hyperhomocyst(e)inemia and Chlamydia pneumoniae IgG seropositivity in patients with coronary artery disease.
Topics: Adult; Antibodies, Bacterial; Austria; Chlamydophila Infections; Chlamydophila pneumoniae; Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multicenter Studies as Topic; Risk Factors; Seroepidemiologic Studies; Smoking | 2002 |
Plasma homocysteine, methylenetetrahydrofolate reductase genotypes, and age at onset of symptoms of myocardial ischemia.
Topics: Adult; Age of Onset; Case-Control Studies; Coronary Disease; Female; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors | 2002 |
Folic acid treatment reduces chemokine release from peripheral blood mononuclear cells in hyperhomocysteinemic subjects.
Topics: Adult; Aged; Case-Control Studies; Chemokine CCL5; Chemokine CXCL1; Chemokine CXCL5; Chemokines; Chemokines, CXC; Chemotactic Factors; Female; Folic Acid; Growth Substances; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Signaling Peptides and Proteins; Interleukin-8; Leukocytes, Mononuclear; Male; Middle Aged | 2002 |
Premature arterial and venous events in three families. Effect of folate levels and MTHFR mutation mediated by family/generation and homocysteine levels.
Topics: Adolescent; Adult; Cardiovascular Diseases; Family Health; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Pedigree | 2002 |
The homocysteine confusion: now, more is better?
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors | 2002 |
Methylenetetrahydrofolate reductase genotype, vitamin B12, and folate influence plasma homocysteine in hemodialysis patients.
Topics: Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Dialysis; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Hyperhomocyst(e)inemia and MTHFR C677T genotypes in patients with central retinal vein occlusion.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Vitamin B 12 | 2002 |
Hyperhomocyst(e)inemia and hemostatic factors: the atherosclerosis risk in communities study.
Topics: Age Factors; Arteriosclerosis; Blood Coagulation Factors; Cardiovascular Diseases; Carotid Artery Diseases; Cross-Sectional Studies; Ethnicity; Female; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Sex Factors; Smoking; Ultrasonography | 2002 |
Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine.
Topics: Adenosine; Animals; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Ischemia; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Prevalence of hyperhomocysteinemia in normal healthy Thai subjects.
Topics: Adult; Age Factors; Aged; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Reference Values; Sex Factors; Thailand | 2001 |
Functional vitamin B(12) deficiency and Alzheimer disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alzheimer Disease; Brain; Homocysteine; Humans; Hyperhomocysteinemia; Oxidation-Reduction; Oxidative Stress; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Effect of vegetarian diet on homocysteine levels.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Luminescent Measurements; Male; Middle Aged; Prevalence; Vitamin B 12 | 2002 |
[The distribution of serum homocysteine and its associated factors in a population of 1 168 subjects in Beijing area].
Topics: Adult; Age Factors; China; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Rural Health; Sex Factors; Urban Health | 2002 |
Is it time to standardize and to measure blood homocysteine levels in patients with heart disease?
Topics: Adult; Cardiovascular Diseases; Health Policy; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Reference Standards; Reproducibility of Results; United States | 2002 |
Genetic and molecular control of folate-homocysteine metabolism in mutant mice.
Topics: Animals; Blotting, Northern; Disease Models, Animal; Female; Folic Acid; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Liver; Methylmalonic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Oligonucleotide Array Sequence Analysis; Signal Transduction | 2002 |
Treatment of hyperhomocysteinemia with folic acid: effects on homocysteine levels, coagulation status, and oxidative stress markers.
Topics: Aged; Analysis of Variance; Biomarkers; Blood Coagulation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Oxidative Stress | 2002 |
Prevalence of hyperhomocysteinemia in an elderly population.
Topics: Age Distribution; Aged; Aged, 80 and over; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Sex Distribution; Vitamin B 12 | 2002 |
The 677C --> T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in epileptic patients affected by systemic lupus erythematosus.
Topics: Adolescent; Adult; Antibodies, Anticardiolipin; Epilepsy; Female; Gene Expression; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoglobulin G; Immunoglobulin M; Lupus Coagulation Inhibitor; Lupus Erythematosus, Systemic; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Protein S | 2002 |
Homocysteine and the stage of atherosclerotic disease: a study in patients suffering from clinically silent and clinically manifest atherosclerotic disease.
Topics: Adult; Aged; Arteriosclerosis; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Severity of Illness Index | 2002 |
Hyperhomocysteinemia and impaired vasomotor function in type 2 diabetes mellitus.
Topics: Adult; Brachial Artery; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Ultrasonography; Vasodilation | 2002 |
Low risk of thrombosis in family members of patients with hyperhomocysteinaemia.
Topics: Adolescent; Adult; Aged; Child; Disease-Free Survival; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Thrombosis | 2002 |
Hyperhomocysteinemia and the risk of thromboembolic phenomenon in patients with chronic renal failure.
Topics: Adult; Aged; Aged, 80 and over; Cerebrovascular Disorders; Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Retrospective Studies; Risk Factors; Thromboembolism | 2002 |
Serum homocysteine level is increased and correlated with endothelin-1 and nitric oxide in Behçet's disease.
Topics: Acute-Phase Proteins; Adolescent; Adult; Behcet Syndrome; Biomarkers; Blood Sedimentation; Endothelin-1; Female; Homocysteine; Humans; Hyperhomocysteinemia; Leukocyte Count; Male; Middle Aged; Neutrophils; Nitric Oxide; Retinal Diseases | 2002 |
The C677T thermolabile variant of methylene tetrahydrofolate reductase on homocysteine, folate and vitamin B12 in a hemodialysis center.
Topics: Adult; Chi-Square Distribution; Female; Folic Acid; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Renal Dialysis; Statistics, Nonparametric; Vitamin B 12 | 2002 |
Between-centre agreement in homocysteine assays: experience from the UK NEQAS proficiency testing scheme.
Topics: Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Fluorescence Polarization Immunoassay; Freeze Drying; Homocysteine; Humans; Hyperhomocysteinemia; Observer Variation; Radioimmunoassay; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity; United Kingdom | 2002 |
Folic acid, Vitamin B(12), and homocysteine in smoking and non-smoking pregnant women.
Topics: Cross-Sectional Studies; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Pregnancy; Pregnancy Complications; Reference Values; Smoking; Vitamin B 12 | 2002 |
Hyperhomocyst(e)inemia, but not methylenetetrahydrofolate reductase C677T mutation, as a risk factor in branch retinal vein occlusion.
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2002 |
Methionine-loading test: evaluation of adverse effects and safety in an epidemiological study.
Topics: Arteriosclerosis; Blood Pressure; Cohort Studies; Dizziness; Epidemiologic Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Nausea; Polymers; Safety | 2002 |
Homocysteine and vascular access thrombosis in hemodialysis patients.
Topics: Adult; Aged; Arteriovenous Fistula; Catheters, Indwelling; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors; Time Factors; Venous Thrombosis | 2002 |
Hyperhomocysteinemia, and low intakes of folic acid and vitamin B12 in urban North India.
Topics: Adult; Anthropometry; Blood Chemical Analysis; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Mental Recall; Obesity; Poverty Areas; Seroepidemiologic Studies; Urban Population; Vitamin B 12 | 2002 |
Homocysteine and C-reactive protein levels in haemodialysis patients.
Topics: Adult; C-Reactive Protein; Case-Control Studies; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Vitamin B 12 | 2001 |
The role of hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) C677T mutation in patients with retinal artery occlusion.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Chromatography, High Pressure Liquid; DNA; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Retinal Artery Occlusion; Retrospective Studies; Risk Factors | 2002 |
Hyperhomocyst(e)inemia induces accelerated transplant vascular sclerosis in syngeneic and allogeneic rat cardiac transplants.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Creatinine; Cystine; Graft Rejection; Graft Survival; Heart Transplantation; Homocysteine; Hyperhomocysteinemia; Male; Postoperative Complications; Rats; Rats, Inbred F344; Rats, Inbred Lew; Sclerosis; Time Factors; Transplantation, Heterotopic; Transplantation, Homologous; Transplantation, Isogeneic; Vascular Diseases | 2002 |