homocysteine and HbS Disease

homocysteine has been researched along with HbS Disease in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's6 (35.29)29.6817
2010's4 (23.53)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
Aiyelokun, OE; Akinsola, OJ; Davies, NO; Ogbenna, AA; Olowoselu, FO; Osunkalu, VO; Taiwo, IA1
Ames, PRJ; Arcaro, A; Caruso, M; Gentile, F; Graf, M; Marottoli, V1
Abd El Hady, NMS; El-Hawwary, AM; Mahmoud, AA; Rizk, MS; Saleh, NY1
Das, K; Das, P; Dash, BP; Dehury, S; Jit, BP; Maske, MM; Meher, S; Mohanty, PK; Patel, S1
Chen, PC; Cheung, AT; Green, R; Lin, X; Miller, JW; Samarron, SL; Wun, T; Zwerdling, T1
Andemariam, B; Colombatti, R1
da Guarda, CC; Dias Zanette, AM; Figueiredo, CV; Goncalves, Mde S; Pitanga, TN; Santana, SS; Santiago, RP; Veloso Cerqueira, BA; Vilas-Boas, W1
Alves de Almeida, E; Belini Junior, E; Bonini-Domingos, CR; da Silva, DGH; de Souza Torres, L; Garcia de Oliveira, R; Lopes de Castro Lobo, C; Marcel Barberino, W; Okumura, JV; Urbinatti Teixeira, V1
Ajayi, OI; Bwayo-Weaver, S; Castro, O; Chirla, S; Daniel, M; Edwards, K; Gordeuk, VR; Lombardo, F; Nouraie, M; Serlemitsos-Day, M1
Glew, RH; Okolo, SN; Okorodudu, A; Shores, J; VanderJagt, DJ1
Brereton, NH; Miller, ER; Resar, LM; Segal, JB1
Meschia, JF; Worrall, BB1
Al-Absi, IK; Al-Subaie, AM; Almawi, WY; Ameen, G; Fawaz, NA; Mahdi, N; Mohammad, AM1
Castro, OL; Houston, PE; Kim, KS; Perlin, E; Rana, S; Sekhsaria, S1
Bakker, AJ; Brouwer, DA; Duits, AJ; Muskiet, FA; Muskiet, FD; Schnog, JJ; van den Berg, GA; van der Dijs, FP; Velvis, HJ1
Fokkema, MR; Muskiet, FA; Muskiet, FD; Schnog, JB; van der Dijs, FP1
Dijck-Brouwer, DA; Duits, AJ; Fokkema, MR; Muskiet, FA; Muskiet, FD; Niessink, B; Schnog, JJ; van der Dijs, FP; van der Wal, TI1

Reviews

1 review(s) available for homocysteine and HbS Disease

ArticleYear
Relevance of Plasma Homocysteine and Methylenetetrahydrofolate Reductase 677TT Genotype in Sickle Cell Disease: A Systematic Review and Meta-Analysis.
    International journal of molecular sciences, 2022, Nov-24, Volume: 23, Issue:23

    Topics: Adult; Anemia, Sickle Cell; Child; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic

2022

Trials

3 trial(s) available for homocysteine and HbS Disease

ArticleYear
Association of plasma homocysteine level with vaso-occlusive crisis in sickle cell anemia patients of Odisha, India.
    Annals of hematology, 2019, Volume: 98, Issue:10

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Aspartate Aminotransferases; Bilirubin; Blood Platelets; Female; Fetal Hemoglobin; Hemolysis; Homocysteine; Humans; L-Lactate Dehydrogenase; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Platelet Activation; Platelet Count; Polymorphism, Genetic; Vascular Diseases

2019
Association of homocysteine and inflammatory-related molecules in sickle cell anemia.
    Hematology (Amsterdam, Netherlands), 2016, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Animals; Child; Female; Homocysteine; Humans; Inflammation Mediators; Interleukin-17; Male; Mice; Transforming Growth Factor beta; Vascular Cell Adhesion Molecule-1

2016
Elevated homocysteine levels indicate suboptimal folate status in pediatric sickle cell patients.
    American journal of hematology, 1998, Volume: 59, Issue:3

    Topics: Adolescent; Anemia, Sickle Cell; Child; Child, Preschool; Dietary Supplements; Female; Folic Acid; Hemoglobin SC Disease; Homocysteine; Humans; Infant; Male; Pyridoxine; Vitamin B 12

1998

Other Studies

13 other study(ies) available for homocysteine and HbS Disease

ArticleYear
Assessment of MTR Rs1805087 SNP as Possible Modifier of Sickle Cell Disease Severity in a Nigerian Population.
    West African journal of medicine, 2022, Nov-30, Volume: 39, Issue:11

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anemia, Sickle Cell; Cross-Sectional Studies; Homocysteine; Humans; Nigeria; Polymorphism, Single Nucleotide

2022
MTHFR C677T Polymorphism, Plasma Homocysteine, and PDGF-AA Levels and Transcranial Doppler Velocity in Children With Sickle Cell Disease.
    Indian pediatrics, 2023, 08-15, Volume: 60, Issue:8

    Topics: Anemia, Sickle Cell; Child; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Platelet-Derived Growth Factor

2023
Homocysteine is associated with severity of microvasculopathy in sickle cell disease patients.
    British journal of haematology, 2020, Volume: 190, Issue:3

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Creatine; Folic Acid; Homocysteine; Humans; Intravital Microscopy; Microcirculation; Middle Aged; Pyridoxal Phosphate; Severity of Illness Index; Thrombotic Microangiopathies; Vitamin B 12

2020
Microvasculopathy and biomarkers in sickle cell disease: the promise of non-invasive real-time in vivo tools.
    British journal of haematology, 2020, Volume: 190, Issue:3

    Topics: Anemia, Sickle Cell; Biomarkers; Heart Transplantation; Homocysteine; Humans

2020
Impact of genetic polymorphisms in key enzymes of homocysteine metabolism on the pathophysiology of sickle cell anemia.
    Free radical biology & medicine, 2017, Volume: 106

    Topics: Adolescent; Adult; Alleles; Anemia, Sickle Cell; Child; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidative Stress; Polymorphism, Genetic; Young Adult

2017
Cobalamin status in sickle cell disease.
    International journal of laboratory hematology, 2013, Volume: 35, Issue:1

    Topics: Adult; Anemia, Sickle Cell; Black or African American; Cross-Sectional Studies; District of Columbia; Homocysteine; Hospitals, Teaching; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Prevalence; Prospective Studies; Renal Insufficiency, Chronic; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2013
Hypocholesterolemia in Nigerian children with sickle cell disease.
    Journal of tropical pediatrics, 2002, Volume: 48, Issue:3

    Topics: Adolescent; Anemia, Sickle Cell; Body Mass Index; Cardiovascular Diseases; Case-Control Studies; Child; Child, Preschool; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Electric Impedance; Female; Homocysteine; Humans; Lipids; Male; Nigeria; Risk Factors; Triglycerides

2002
Concentrations of B vitamins and homocysteine in children with sickle cell anemia.
    Southern medical journal, 2004, Volume: 97, Issue:2

    Topics: Anemia, Sickle Cell; Black People; Case-Control Studies; Child; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 6; Vitamins

2004
New advances in identifying genetic anomalies in stroke-prone probands.
    Current neurology and neuroscience reports, 2004, Volume: 4, Issue:5

    Topics: Anemia, Sickle Cell; Arteriosclerosis; Dementia, Multi-Infarct; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Homocysteine; Humans; Lipid Metabolism; Lipoproteins; MELAS Syndrome; Mutation; Polymorphism, Genetic; Stroke

2004
Association of the methylenetetrahydrofolate reductase A1298C but not the C677T single nucleotide polymorphism with sickle cell disease in Bahrain.
    Hemoglobin, 2006, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Bahrain; Chi-Square Distribution; Child; Female; Genotype; Haplotypes; Homocysteine; Humans; Likelihood Functions; Male; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide

2006
Homocysteine in sickle cell disease: relationship to stroke.
    The American journal of medicine, 1997, Volume: 103, Issue:3

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Cerebrovascular Disorders; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Infant; Logistic Models; Male; Middle Aged; Odds Ratio; Severity of Illness Index

1997
Folate status assessment and folic acid supplements in sickle cell disease.
    Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:8

    Topics: Anemia, Sickle Cell; Dietary Supplements; Erythrocytes; Folic Acid; Homocysteine; Humans; Nutritional Status

2001
Optimization of folic acid, vitamin B(12), and vitamin B(6) supplements in pediatric patients with sickle cell disease.
    American journal of hematology, 2002, Volume: 69, Issue:4

    Topics: Adolescent; Anemia, Sickle Cell; Child; Dietary Supplements; Erythrocytes; Female; Folic Acid; Hemoglobin SC Disease; Homocysteine; Humans; Male; Nutrition Policy; Vitamin B 12; Vitamin B 6

2002