homocysteine and Genetic Predisposition

homocysteine has been researched along with Genetic Predisposition in 389 studies

Research

Studies (389)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	20 (5.14)	18.2507
2000's	184 (47.30)	29.6817
2010's	160 (41.13)	24.3611
2020's	25 (6.43)	2.80

Authors

Authors	Studies
Chen, XR; Huang, LW; Li, J; Li, LL; Yu, M	1
Guo, H; He, M; He, S; Jiang, H; Li, W; Liu, X; Long, P; Wang, H; Wu, T; Yu, K; Yuan, Y; Zhang, X; Zhang, Y; Zhang, Z	1
Romdoni, R; Sargowo, D; Sugijo, H; Widjajanto, E	1
Alvarez, S; Amar, E; Brami, C; Clément, A; Clément, P; Davy, C; Jacquesson-Fournols, L; Lalau-Keraly, M; Menezo, Y	1
Bu, X; Chen, J; Guo, D; He, J; Kelly, TN; Li, C; Peng, H; Shan, G; Shen, C; Shi, M; Sun, X; Sun, Y; Wang, A; Xu, T; Zhang, Y; Zhao, J; Zhong, C; Zhu, Z	1
Guo, H; He, M; Jiang, J; Long, P; Mo, T; Niu, R; Peng, R; Shi, L; Wang, Q; Wang, Y; Wu, T; Xu, C; Yang, H; Zhang, X	1
He, GW; Lun, LM; Tian, QW; Xuan, C; Yue, K; Zhang, SY; Zhang, XC; Zhao, P; Zhu, J	1
Dai, J; Deng, B; Ding, H; Ding, Y; Jin, G; Li, G; Ni, J; Qi, Q; Ren, C; Wang, T; Yan, C	1
Deng, S; Fu, L; Hu, YQ; Li, YN; Luo, D; Wu, B	1
Sookaromdee, P; Wiwanitkit, V	1
Fu, L; Hu, YQ	1
Godfrey, O; Huang, X; Li, D; Zhang, C; Zhang, W; Zhao, Q	1
Abdollahimajd, F; Amani, M; Bagheri Hamidi, A; Gholami, M; Mohammad Amoli, M; Namazi, N; Uitto, J; Vahidnezhad, H; Youssefian, L	1
Chen, S; Furuta, Y; Hata, J; Hirakawa, Y; Honda, T; Kitazono, T; Ninomiya, T; Ohara, T; Oishi, E; Sakata, S; Shibata, M; Yoshida, D	1
Du, B; Huang, X; Li, D; Ren, B; Yue, L; Zhang, C; Zhang, W; Zhao, Q	1
Ben Messaoud, M; Bouzidi, N; Ferchichi, S; Fodha, H; Gamra, H; Hassine, M; Maatouk, F	1
Chen, X; Kong, Y; Lu, L; Wang, J; Xu, X; Ye, Z; Zheng, J	1
Chen, S; Fu, G; Wang, Y; Xu, T; Yang, F; Zhang, K; Zhang, W	1
Lu, Y; Sun, X; Wang, Q; Wang, Z; Zheng, L	1
Cao, Y; Cui, L; Ni, J; Su, N; Yao, M; Zhang, D; Zhang, S; Zhou, L; Zhu, Y	1
Feng, W; Huang, Y; Jiao, J; Liu, M; Ma, Y; Mo, W; Pan, Y; Tian, D; Wang, X; Xiao, Y; Yang, L; Zhang, Y	1
Gao, X; Hu, S; Hua, L; Jia, L; Jiang, X; Tan, JS; Wang, XJ; Wu, Y; Xu, XQ; Yan, XX	1
Alvarez, S; Amar, E; Brack, M; Brami, C; Chouteau, J; Clement, A; Clement, P; Cohen, M; Cornet, D; D' Amato, G; Dale, B; Huong, TM; Jacquesson-Fournols, L; Mares, P; Ménézo, Y; Neveux, P; Patrizio, P; Sage, JC; Servy, E; Viot, G	1
Amato, F; Bruzzese, D; Castaldo, G; Cernera, G; Comegna, M; Elce, A; Liguori, R; Lullo, AMD; Minno, AD; Zarrilli, F	1
In, S; Lee, HS; Park, T	1
Miyazaki, A; Nakamura, Y; Nakano, M; Shiraki, M; Suzuki, T; Takahashi, J; Urano, T; Watanabe, K	1
Haider, G; Iqbal, K; Iqbal, MP; Iqbal, SP; Mehboobali, N; Parveen, S; Tareen, AK	1
Cao, Y; Jiang, Y; Kong, X; Li, P; Liu, Q; Ma, L; Yan, M; Zhang, H; Zhao, H; Zhao, T	1
Dai, XL; Jin, MH; Liu, GC; Mi, NN; Ren, XY; Wang, J; Wang, SQ; Zhang, J	1
Hong, YC; Kim, KN; Lee, MR; Lim, YH	1
Li, J; Li, PQ; Li, Y; Wang, YZ; Xie, DX; Xie, HH; Xie, XD; Zhang, AA	1
Elizabeth, KE; Jissa, VT; Pillai, MR; Praveen, SL; Preethi, NR	1
Bennett, DA; De Jager, PL; Felsky, D; Nazeri, A; Roostaei, T; Schneider, JA; Voineskos, AN	1
Duan, L; Hu, J; Liu, Y; Wang, J; Xiong, X	1
Hussain, T; Kutala, VK; Lakshmitha, G; Naushad, SM; Nivetha, S; Rama Devi, AR; Stanley, AB	1
Cushman, M; Duan, Q; Durda, P; Ellis, J; Gross, MD; Keating, BJ; Lange, EM; Lange, LA; Li, J; Li, Y; Olson, NC; Pankratz, N; Raffield, LM; Reiner, AP; Rich, SS; Tracy, RP; Wassel, CL; Willis, MS; Wilson, JG	1
Begum, R; Jadeja, SD; Mansuri, MS; Marfatia, YS; Patel, H; Singh, M	1
Ahmed, A; Ahsan, H; Finnell, RH; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Kibriya, MG; Levy, D; Liu, X; Navas-Acien, A; Niedzwiecki, MM; Parvez, F; Siddique, AB; Slavkovich, V; Zhu, H	1
Grywalska, E; Krawiec, P; Pac-Kozuchowska, E	1
Cao, Y; Jiang, Y; Kong, X; Li, P; Liu, P; Liu, Q; Ma, L; Yan, M; Zhang, H; Zhao, H; Zhao, T	1
Kang, SS; Rosenson, RS	1
Brown, MJ; Chen, W; Cheng, H; Jin, H; Levy, MA; Sheng, X; Tian, J	1
Bankura, B; Das, M; Munian, D; Paul, S; Sadhukhan, S	1
Brandmayr, W; Enko, D; Halwachs-Baumann, G; Kriegshäuser, G; Meinitzer, A; Schnedl, WJ	1
Bertini, V; Bonuccelli, A; Marchese, P; Orsini, A; Peroni, DG; Sammartino, I; Valetto, A	1
Shute, C	1
Gai, A; Govone, F; Rainero, I; Roveta, F; Rubino, E; Vacca, A	1
Denisova, AG; Drujinina, TA; Kulyutsina, ER; Levashova, OA; Tatarchenko, IP	1
Cao, Y; Jiang, Y; Li, P; Liu, Q; Ma, L; Niu, W; Zhao, H; Zhao, T	1
Arora, R; Bansal, AK; Bhattacharya, R; Hasan, T; Sharma, GS; Singh, LR	1
Cao, S; Fei, X; Luo, Z; Qin, B; Sui, X; Wang, F; Xin, Y; Xu, N; Yang, J; Yang, Z; Zhang, Y; Zhang, Z; Zhao, H; Zhao, X	1
Fu, J; Huang, J; Li, Q; Lin, Z; Sun, Y; Wang, W; Xu, J; Zeng, D	1
Aloui, M; Baara, A; Ben Fradj, MK; Ben Halima, M; Ben Jemaa, N; Ben Wafi, S; Boulares, M; Feki, M; Gaigi, SS; Jemaa, R; Kallel, A; Lassoued, M; Mahjoubi, I; Marrakchi, R; Midani, F; Nasri, K; Omar, S; Soussi, M	1
Jadavji, NM; Murray, LK	1
Arslan, Z; Guler, A; Tavlasoglu, M; Yesil, FG	1
Fan, S; Li, Y; Liu, Y; Lu, X; Sun, G; Wang, D; Wang, Y; Yang, B; Zheng, Q; Zhi, X	1
Craig, JM; Dear, A; Golledge, J; Krishna, SM; Norman, PE	1
Grützner, N; Heilmann, RM; Holzenburg, A; Rangachari, VR; Steiner, JM; Stupka, KC; Suchodolski, JS; Weber, K	1
Fekih Mrissa, N; Gritli, N; Klai, S; Machgoul, S; Mazigh, C; Mrad, M; Mrissa, R; Nsiri, B; Sayeh, A; Zaouali, J	1
Bezerra, LC; D'Almeida, V; de Carvalho, SC; de Oliveira, CP; Gomes, AV; Muniz, MT; Pereira, LM; Silva, KA; Siqueira, ER; Siqueira, MD	1
Fekih-Mrissa, N; Gritli, N; Klai, S; Mansour, M; Mrad, M; Mrissa, R; Nsiri, B	1
Flicker, L; Golledge, J; Hankey, GJ; McCaul, KA; Norman, PE; van Bockxmeer, FM; Wong, YY; Yeap, BB	1
Fekih-Mrissa, N; Gritli, N; Klai, S; Mansour, M; Mansouri, L; Mrissa, R	1
Day, EC; Shlipak, MG	1
Chen, YJ; Duan, WY; Gong, XH; Huang, GY; Jiang, SS; Jin, L; Lu, CQ; Peng, QQ; Qiao, B; Shen, HB; Wang, HY; Zhao, JY	1
Ahmadi, KR; Bandinelli, S; Bis, JC; Blom, H; Brown, MJ; Chambers, JC; Chasman, DI; Chen, C; Chen, YD; Clarke, RJ; Cotlarciuc, I; Dehghan, A; den Heijer, M; Erdmann, J; Ferrucci, L; Goel, A; Hamsten, A; Hazra, A; Hofman, A; Hunter, DJ; Jacques, P; Johnson, AD; Kampman, E; Kathiresan, S; Kiel, DP; Kiemeney, LA; Kooner, JS; Kraft, P; Lindemans, J; Mälarstig, A; McKnight, B; Mooser, V; Nelson, CP; O'Donnell, CJ; Pare, G; Psaty, BM; Rader, DJ; Reilly, MP; Ridker, PM; Rivadeneira, F; Rose, LM; Samani, NJ; Schunkert, H; Schwartz, SM; Seedorf, U; Selhub, J; Siscovick, DS; Tanaka, T; Ueland, PM; Uitterlinden, AG; van Meurs, JB; Vermeulen, SH; Vollenweider, P; Waeber, G; Waterworth, DM; Watkins, H; Witteman, JC; Yuan, X	1
Cha, SH; Choi, YS; Jeon, YJ; Kim, JH; Kim, NK; Kim, YR; Lee, BE; Lee, WS; Rah, H; Shin, JE	1
Mohammed, D; Rezk, NA; Zidan, HE	1
Ellis, SM; Melse-Boonstra, A; Moss, SJ; Nienaber-Rousseau, C; Towers, GW	1
Arab, A; Bogari, N; Elhawary, NA; Hewedi, D; Shaibah, H; Tayeb, MT; Teama, S	1
Huang, J; Huang, T; Li, D; Ren, J	1
Chen, D; Chen, F; Guo, W; Hu, Y; Wei, Y; Wu, T; Xiong, J; Zuo, S	1
Bain, N; Farkas, M; Ineichen, BV; Kallweit, U; Keskitalo, S; Klotz, L; Linnebank, M; Weller, M	1
Chen, JX; Dai, W; Gao, TW; Guo, S; Li, CY; Li, K; Shi, Q; Song, P; Wang, G; Wang, XW; Wei, C	1
Bahari, M; Jooyan, N; Karimi, M; Saffari, B; Senemar, S; Yavarian, M	1
Ishii, I	1
Åkesson, K; Garg, G; Gerdhem, P; Kumar, J; Luthman, H; McGuigan, FE; Ridderstråle, M	1
Chedraui, P; Escobar, GS; Genazzani, A; Hidalgo, L; Pérez-López, FR; Ramirez, C; Salazar-Pousada, D; Simoncini, T; Villao, A	1
Guo, X; Han, X; Li, X; Liu, W; Liu, Y; Peng, Y; Sun, L; Tian, J; Zhang, R	1
Cho, YK; Jeon, YJ; Kim, EJ; Kim, HS; Kim, JO; Kim, NK; Kim, OJ; Oh, D; Oh, SH; Shin, BS	1
Borgohain, R; Kumudini, N; Kutala, VK; Mridula, R; Naushad, SM; Uma, A	1
Ahmadi, KR; Cotlarciuc, I; Dichgans, M; Fornage, M; Hasan, N; Holliday, EG; Ikram, MA; Kittner, SJ; Malik, R; Markus, HS; Meschia, JF; Mitchell, BD; Paré, G; Psaty, BM; Rinne, PE; Rosand, J; Sharma, P; Uitterlinden, AG; van Meurs, JB; Worrall, BB	1
Anello, G; Antonucci, I; Barone, C; Bosco, P; Coppedè, F; Denaro, M; Lorenzoni, V; Migliore, L; Romano, C; Stuppia, L	1
Kumar, P; Mishra, OP; Rai, V; Yadav, SK; Yadav, U	1
Jeon, SB; Kang, DW; Kim, JS; Kwon, SU	1
Qin, F; Tang, O; Wu, J	1
Choi, JU; Han, IB; Jeon, YJ; Kim, DS; Kim, HS; Kim, NK; Park, YS	1
Whayne, TF	1
Chasman, DI; Cornelis, MC; Fornage, M; Foy, M; Gladyshev, VN; He, K; Hu, FB; Jordan, JM; Kraft, P; Morris, S; Mozaffarian, D; Rimm, EB; Xun, P	1
Gupta, ED; Liew, SC	1
Bartell, T; Chen, Z; Hong, X; Hou, F; Huo, Y; Ji, Y; Kong, X; Tang, G; Wang, B; Wang, G; Wang, X; Xu, X	1
He, ZY; Liu, HN; Liu, X; Zhu, RX; Zhu, Y	1
Gao, B; Ji, QH; Liu, XD; Liu, ZR; Ma, YY; Shi, M; Sun, D; Wang, B; Xu, X; Zhao, G	1
Karmadonova, NA; Karpenko, AA; Klevanets, JE; Kozyreva, VS; Shilova, AN; Subbotovskaya, AI	1
Givimani, S; Neamtu, D; Rehman, S; Tyagi, SC; Vacek, TP; Yu, S	1
Chen, X; Hou, X; Shi, J	1
Cao, Y; Chen, QY; Fang, Y; Li, H; Liu, N; Liu, YC; Ma, J	1
Alataş, Ö; Keleş, F; Kılıç, Z; Koşger, P; Özdemir, G; Uçar, B; Yıldırım, A	1
Chen, YG; Qu, Y; Sun, Y; Wu, HL; Yu, LM; Zhang, HL	1
Bozkurt, A; Kasapoglu, B; Kosar, A; Turkay, C; Yalcin, KS	1
Gupta, V; Jaiswal, SK; Kumar, A; Mishra, OP; Rai, AK; Raman, R; Sukla, KK	1
Hwang, SG; Jang, HG; Jeon, YJ; Kim, JO; Kim, JW; Kim, NK; Kwon, SW; Oh, D; Oh, J; Park, HM	1
Ágg, B; Benke, K; Harsányi, G; Mátyás, G; Maurovich-Horvat, P; Merkely, B; Nagy, ZB; Odler, B; Pólos, M; Radovits, T; Szabolcs, Z; Szilveszter, B; Szokolai, V	1
Cho, SH; Jeon, YJ; Kim, JO; Kim, JW; Kim, NK; Ko, JJ; Oh, D; Oh, J; Yoo, JK	1
Imoto, I; Kinoshita, M; Nishi, A; Numata, S; Ohmori, T; Tajima, A	1
Fu, LB; He, LJ; Li, QL; Liu, XR; Peng, XX; Song, WQ	1
Dai, SX; Huang, JF; Li, WX; Lv, WW; Pan, ML	1
Bonacasa, B; Bosch, V; Corno, A; Delgado, JL; Fenoy, FJ; Hernández, I; Hernández, M; López, B; Mendiola, J; Pertegal, M	1
Kinoshita, M	1
Cha, DH; Jeon, YJ; Kim, IJ; Kim, JO; Kim, NK; Kim, OJ; Kim, SH; Lee, BE; Lim, SW; Moon, JY; Sung, JH	1
Cui, NH; Han, YD; Huang, ZL; Li, ZH; Qiao, C; Wang, XB; Wei, L; Yan, M; Zheng, F	1
Abbondanza, S; Davin, A; Guaita, A; Mangieri, M; Polito, L; Poloni, TE; Vaccaro, R; Villani, S	1
Faas, MM; Holwerda, KM; Lely, AT; Nolte, IM; Staff, AC; van Goor, H; Weedon-Fekjær, MS	1
Hao, F; Hu, Q; Li, J; Teng, W; Wang, N	1
Chen, YY; Wang, BN; Yu, XP	1
Huo, Y; Jiang, S; Li, J; Li, Z; Tang, G; Venners, SA; Wang, B; Wang, Y; Xu, X; Zhang, Y	1
Lan, S; Li, Y; Liu, X; Song, A; Wu, L; Zhao, L	1
Alrokayan, SA; Bharathi, V; Hussain, T; Krishna Prasad, C; Naik, U; Radha Rama Devi, A; Sai Shruti, P; Shaik Mohammad, N	1
Bickel, C; Blankenberg, S; Lackner, K; Lubos, E; Proust, C; Rupprecht, H; Schnabel, RB; Sinning, C; Tregouet, D; Westermann, D; Zengin, E	1
Imoto, I; Kinoshita, M; Muraki, S; Nishi, A; Numata, S; Ohmori, T; Tajima, A; Tsuchiya, A; Umehara, H; Watanabe, SY	1
Gluszek, J; Oszkinis, G; Pawlak, AL; Radziemski, A; Strauss, E; Supinski, W	1
Abd El-Aziz, TA; Mohamed, RH	1
Amaral, FM; Daldegan, MB; Grisolia, CK; Lordelo, GS; Miranda-Vilela, AL; Ribeiro, IF	1
Aoki, K; Esaki, M; Hirose, H; Ikeda, M; Kosuge, T; Morizane, C; Ohnami, S; Okusaka, T; Saito, D; Saito, I; Sakamoto, H; Sakamoto, Y; Sato, Y; Shimada, K; Sugimura, H; Ueno, H; Yoshida, T; Yoshimura, K	1
Ritch, R	1
Dayal, S; Lentz, SR	1
Cheng, CH; Huang, MC; Huang, YC; Lee, BJ; Lin, PT; Tsai, TP	1
Arnett, DK; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Lynch, A; Maitland-van der Zee, AH	1
Abbate, R; Bolli, P; Giusti, B; Magi, A; Pratesi, C; Pratesi, G; Pulli, R; Saracini, C; Sestini, I; Sticchi, E	1
Ray, JG	1
Smith, AD	1
Almeida, OP; Flicker, L; Hankey, GJ; Jamrozik, K; McCaul, K; Norman, P	1
Chin-Dusting, J; De Silva, DA; Kingwell, B; Koh, TH; Moe, KT; Wong, MC; Wong, P; Woon, FP	1
Csiki, Z; Shoenfeld, Y; Szamosi, S; Szegedi, G; Szekanecz, Z; Szoke, G; Szolnoki, E; Szomják, E; Szucs, G	1
Govindaiah, V; Krishna, PC; Naushad, SM; Prabhakara, K; Radha Rama Devi, A	1
Chen, T; DelBono, E; Fan, BJ; Grosskreutz, C; Haines, JL; Pasquale, L; Rhee, D; Wiggs, JL	1
Armon, MP; Finglas, PM; Jennings, BA; Khandanpour, N; Loke, YK; Meyer, FJ; Willis, G; Wright, AJ	1
Barcikowska, M; Chodakowska-Zebrowska, M; Czapski, GA; Gabryelewicz, T; Karciauskas, G; Kobryś, M; Pfeffer, A; Religa, D; Strosznajder, JB; Styczyńska, M	1
Deng, L; Lawrance, AK; Rozen, R	1
de la Plata, CM; Diaz-Arrastia, R; Fields, BA; Gong, YH; Hynan, LS; Qu, BX; Rosenberg, RN; Weiner, MF; Womack, KB	1
Brody, LC; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM	1
Banerjee, R; Benga, I; Cornean, R; Craciun, EC; Dronca, E; Dronca, M; Endreffy, E; Ferencz, BK; Iftene, F; Kaucsár, T; Paşca, SP	1
Acuto, S; Bono, A; Campisi, G; Guglielmini, E; Scazzone, C	1
Cavarra, E; De Cunto, G; Fineschi, S; Giustarini, D; Lungarella, G; Rossi, R	1
Agostinelli, S; Chiarelli, F; D'Adamo, E; de Giorgis, T; Giannini, C; Mohn, A; Scarinci, A	1
Agrawal, S; Baburaj, VP; Sankhwar, SN; Sharma, RK; Tripathi, G	1
Hiraoka, M; Kagawa, Y; Kageyama, M	1
Feng, LG; Hu, J; Song, ZW; Xin, F	1
Alonso-Arranz, A; Bravo, Y; Castillo, J; Oterino, A; Pascual, J; Quintela, E; Ruiz-Alegria, C; Toriello, M; Valle, N	1
Boreham, CA; Buckley, PT; Kealey, C; McNulty, H; Mitchell, LE; Murray, L; Scott, JM; Stanisławska-Sachadyn, A; Strain, JJ; Whitehead, AS; Woodside, JV; Young, IS	1
Fenger, M; Husemoen, LL; Jørgensen, T; Linneberg, A; Thuesen, BH	1
Chen, SD; Ding, JQ; Fan, CN; Ma, JF; Song, YY; Xin, XY; Yang, GY	1
Gültepe, M; Ipçioğlu, OM; Kiralp, MZ; Ozçakar, L; Ozcan, O	1
Chiang, TR; Ho, CS; Hu, CJ; Hung, YL; Sheu, JJ; Tseng, IJ; Yeh, CY; Yu, JM; Yuan, RY	1
Johnston, SC; Suri, MF	1
Naumov, AV; Razvodovskiĭ, IuE	1
Duan, ZQ; Fan, YY; He, JA; Hu, XH; Liu, CW; Xin, SJ; Yang, DH; Yang, J; Zhang, J; Zhang, Q; Zhang, ZS	1
Bellon, A; Frieling, H; Jay, TM; Krebs, MO; Mainguy, G	1
Chmurzynska, A; Malinowska, A	1
Steegers, EA; Steegers-Theunissen, RP; Uitterlinden, AG; van Meurs, J; van Rooij, IA; Vujkovic, M; Yazdanpanah, N	1
McNulty, H; Scott, JM; Strain, JJ; Ward, M; Wilson, CP	1
Cullman, I; Dahlin, AM; Eklöf, V; Hallmans, G; Henriksson, ML; Hultdin, J; Johansson, I; Palmqvist, R; Van Guelpen, B	1
Belcastro, V; Calabresi, P; Castrioto, A; Gorgone, G; Ientile, R; Menichetti, C; Pierguidi, L; Pisani, F; Rossi, A; Tambasco, N	1
Adair, LS; Borja, JB; Croteau-Chonka, DC; Gaulton, KJ; Kuzawa, CW; Lange, EM; Lange, LA; Levy, S; Li, Y; Marvelle, AF; McDade, TW; Mohlke, KL; Qin, L; Wang, Y	1
Blinov, MN; Kapustin, SI; Klenkova, NA; Saltykova, NB; Shmeleva, VM	1
Dear, AE; Golledge, J; Krishna, SM; Norman, PE	1
Hasdai, D; Iakobishvili, Z; Kaluski, DN; Lev, E; Mager, A; Messika, AH; Shohat, M	1
Bukowska, H; Chełstowski, K; Honczarenko, K; Jastrzębska, M; Kozłowska-Wojciechowska, M; Makarewicz-Wujec, M; Masztalewicz, M; Mierzecki, A	1
Abbate, R; Bolli, P; Giusti, B; Lotta, LA; Magi, A; Mannucci, PM; Martinelli, I; Peyvandi, F; Rasura, M; Rubattu, S; Saracini, C; Volpe, M	1
Cho, YJ; Lee, EJ; Yoon, YJ	1
Almawi, WY; Jawad, LH; Juma, EA; Keleshian, SH; Nemr, R; Salman, RA	1
Crncević, Z; Jakovljević, M; Milicić, D; Reiner, Z	1
Buyukbas, S; Cosar, E; Erdogan, MO; Eser, B; Eser, O; Koken, R; Solak, M; Yildiz, SH	1
Chen, Z; Ge, L; Huang, S; Jiang, T; Jiang, Y; Lei, Y; Xia, B; Zhao, J; Zhou, F	1
Aggio, S; Chinaglia, M; Grassetto, G; L'Erario, R; Mazza, A; Montemurro, D; Pastore, G; Piergentili, C; Rubello, D; Zamboni, S; Zanier, A; Zanon, F	1
Choi, JK; Hong, SH; Kim, NK; Kim, OJ; Lee, JH; Oh, D; Oh, SH	1
Gong, YH; Hynan, LS; Qu, BX; Rosenberg, RN; Rossetti, H; Weiner, MF; Womack, KB	1
Kim, HS; Kim, NK; Kim, OJ; Kim, WC; Oh, SH	1
Bilge, I; Emre, S; Ergen, A; Isbir, T; Sirin, A; Sucu, A; Yilmaz, A	1
Collin, SM; Cox, A; Davis, M; Donovan, JL; Hamdy, FC; Johnston, C; Lane, JA; Lewis, SJ; Marsden, G; Martin, RM; Metcalfe, C; Neal, DE; Refsum, H; Smith, AD; Smith, GD	1
Casey, A; Schinzel, H; Walter, PK; Wilmanns, C	1
Bashamboo, A; Belloc, S; Benkhalifa, M; Cohen-Bacrie, P; Dessolle, L; McElreavey, K; Montjean, D; Ravel, C; Siffroi, JP	1
Gao, X; Gu, X; Han, L; Qiu, W; Wang, F; Wang, Y; Yang, Y; Ye, J; Zhang, H; Zhang, Y	1
Carvalho, MG; das C L E Silva, F; Faria, MC; Fernandes, AP; Freitas, FR; Gomes, KB; Mota, AP; Santos, ME	1
Andrikopoulos, V; Barbatis, C; Bastounis, E; Drougou, A; Georgopoulos, S; Klonaris, C; Koliaraki, V; Lioupis, C; Mamalaki, A	1
Chabik, G; Członkowska, A; Gromadzka, G; Przybyłkowski, A; Rudnicka, M	1
Crott, JW; Huang, T; Lai, CQ; Lee, YC; Li, D; Ordovas, JM; Parnell, LD; Shen, J; Smith, CE; Tucker, KL	1
Almeida, OP; Flicker, L; Ford, AH; Hankey, GJ; Norman, P; van Bockxmeer, FM	1
Badjatia, N; Claassen, J; Connolly, ES; DeRosa, PA; Ducruet, AF; Fernandez, L; Grobelny, BT; Hickman, ZL; Kotchetkov, IS; Lee, K; Mayer, SA; Narula, R; Zacharia, BE	1
Chitlur, M; Lusher, J; Nahar, A; Rajpurkar, M; Ravindranath, Y; Sabo, C	1
Liang, S; Ren, YY	1
Ahmadi, KR; Andrew, T; Clement, G; Cotlarciuc, I; Dew, T; Gill, R; Sherwood, R; Surdulescu, G	1
Hallmans, G; Hultdin, J; Nilsson, TK; Stegmayr, B; Van Guelpen, B; Weinehall, L; Winkvist, A	1
Bertollo, EM; Biselli, JM; Carvalho, VM; Eberlin, MN; Haddad, R; Marucci, GH; Pavarino, EC; Riccio, MF; Valentin, S; Vannucchi, H; Zampieri, BL	1
Hong, SH; Kim, NK; Kim, OJ; Kim, TG; Min, KT; Oh, D; Oh, SH	1
Alfonso, H; Almeida, OP; Flicker, L; Ford, AH; Hankey, GJ; Norman, PE; van Bockxmeer, FM	1
Chandak, GR; Gayathri, P; Ghule, S; Godbole, K; Kanitkar-Damle, A; Memane, N; Sasirekha, BV; Sheth, J; Suresh, S; Yajnik, CS	1
Chen, L; Cheng, X; Hong, K; Hu, J; Liu, L	1
Hitri, K; Kondacs, A; Mandi, Y; Nedo, E; Somogyvari, F; Szaniszlo, I; Szekeres, M; Szolnoki, Z	1
Chang, HM; Chen, CP; Foo, JN; Kasiman, K; Liu, J; Low, HQ; Ng, SS; Tai, ES; Thalamuthu, A; Wong, MC	1
Brody, LC; Browne, ML; Caggana, M; Carter, TC; Druschel, CM; Kay, DM; Liu, A; Mills, JL; Romitti, PA	1
Carmichael, SL; Gilbert, DA; Hardin, J; Hoffmann, TJ; Lammer, EJ; Lazaruk, K; Lipzen, A; Marini, NJ; Pennacchio, LA; Rine, J; Shaw, GM; Stein, JB; Witte, JS; Wright, C	1
McNulty, H; Pentieva, K; Strain, JJ; Ward, M	1
Karahan, O; Manduz, S; Yucel, O; Zorlu, A	1
Cha, SH; Choi, DH; Choi, Y; Choi, YS; Jeon, YJ; Kim, NK; Ko, JJ; Rah, H; Shim, SH	1
Ben Hamouda, H; Braham, H; Ghanmi, S; Hamza, HA; Hassine, M; Sfar, MT; Soua, H; Wannes, S	1
Ali, A; Bhargava, S; Parakh, R; Saxena, R; Srivastava, LM	1
Celik, A; Celikyay, ZR; Ceyhan, K; Damar, IH; Erkorkmaz, U; Kadi, H; Koc, F; Ozcetin, M; Sogut, E; Yerli, Y	1
Hamada, A; Mori, H; Mori, M; Taguchi, T; Yamori, Y	1
Jayaprakash, PG; Lalitha, P; Pillai, MR; Ragasudha, PN; Thulaseedharan, JV; Wesley, R	1
Cassano, PA; Clark, AG; Gaziano, JM; Litonjua, AA; Stover, PJ; Tucker, KL; Vokonas, PS; Weiss, ST; Wells, MT; Wernimont, SM	1
Białecka, M; Budrewicz, S; Droździk, M; Gorzkowska, A; Gołąb-Janowska, M; Honczarenko, K; Jarosz, M; Koziorowska-Gawron, E; Kurzawski, M; Mak, M; Robowski, P; Roszmann, A; Sitek, EJ; Sławek, J	1
Chen, K; Jin, X; Yan, L; Yin, G; Zhang, Z	1
Jeon, YJ; Kim, NK; Kim, OJ; Kim, SY; Oh, D; Oh, SH; Shin, BS	1
Campolo, J; Cozzi, L; De Maria, R; Marocchi, A; Parodi, O; Parolini, M; Patrosso, MC; Penco, S	1
Bopp, G; Hoefgen, B; Kallweit, U; Linnebank, M; Maier, W; Moskau, S; Schütz, CG; Semmler, A; Wüllner, U	1
Ali, A; Kumari, P; Raman, R; Singh, SK; Sukla, KK	1
Baurley, J; Crott, JW; Figueiredo, JC; Haile, RW; Levine, AJ	1
Adamek, L; Domagala, TB; Nizankowska, E; Sanak, M; Szczeklik, A	1
Delport, R; Hillermann, R; Kotze, MJ; Loubser, L; Odendaal, HJ; Scholtz, CL; Thiart, R; Vermaak, WJ	1
Kareinen, A; Laakso, M; Lehto, S; Nieminen, MS; Pajunen, P; Syvänne, M; Viitanen, L	1
Finnell, RH; Lammer, EJ; Shaw, GM; Volcik, KA	1
Gala, JL; Hainaut, P; Heusterspreute, M; Jaumotte, C; Lavenne, E; Moriau, M; Verhelst, D; Wallemacq, P; Zech, F	1
Atta, IA; Ben-Yehuda, A; Friedman, G; Goldschmidt, N; Haviv, YS; Shpichinetsky, V	1
Grzeszczak, W; Gumprecht, J; Zukowska-Szczechowska, E; Zychma, MJ	1
Furie, KL; Kelly, PJ; Kistler, JP; Plomaritoglou, A; Rosand, J; Shih, VE; Silveira, S	1
Blom, HJ; Boers, GH; den Heijer, M; Kluijtmans, LA; Lievers, KJ; Trijbels, FJ; Verhoef, P	1
Bendlová, B; Hrach, K; Hyánek, J; Kahleová, R; Kozich, V; Nováková, I; Palyzová, D; Zvára, K; Zvárová, J	1
Law, M; Morris, JK; Wald, DS	1
Blom, HJ; Boers, GH; Den Heijer, M; Heil, SG; Kluijtmans, LA; Lievers, KJ; Trijbels, FJ; Verhoef, P	1
Araki, I; Fukasawa, M; Kamiyama, M; Matsushita, K; Mikami, Y; Takeda, M; Yamagata, Z	1
Boreham, CA; Kluijtmans, LA; McMaster, D; McNulty, H; McPartlin, J; Murray, L; Scott, JM; Strain, JJ; Whitehead, AS; Young, IS	1
Afman, LA; Blom, HJ; Kluijtmans, LA; Lievers, KJ; Trijbels, FJ	1
Boreham, CA; Brown, KS; Evans, AE; Kluijtmans, LA; McMaster, D; McNulty, H; Mitchell, LE; Murray, L; Strain, JJ; Whitehead, AS; Woodside, J; Yarnell, JW; Young, IS	1
Anábitarte, A; Díaz-Cremades, JM; Ferrario, CM; Fiuza, D; Hernández, E; Hernández-Perera, O; Losada, A; Rodríguez-Esparragón, F; Rodríguez-Pérez, JC; Yunis, C	1
Favier, A; Galan, P; Guilland, JC; Hercberg, S; Potier de Courcy, G	1
Lucock, M; Yates, Z	2
Blom, HJ; den Heijer, M; Klerk, M; Kluijtmans, LA; Kok, FJ; Lievers, KJ; Schouten, EG; Verhoef, P	1
Alamo-Santana, F; Macías-Reyes, A; Rodríguez-Esparragón, FJ; Rodríguez-Pérez, JC	1
Anello, G; Barone, C; Bosco, P; Caraci, F; Guéant, JL; Guéant-Rodriguez, RM; Namour, F; Romano, A; Romano, C	1
Cito, G; D'Aniello, G; Fineschi, D; Florio, P; Guidoni, CG; Petraglia, F; Sabatini, L; Severi, FM	1
Braun, S; Burghartz, M; Kastrati, A; Koch, W; Kölling, K; Lengnick, H; Mehilli, J; Ndrepepa, G; Schömig, A	1
Qiu, L; Song, YH; Yan, SK	1
Hiraoka, M; Kagawa, Y; Kato, K; Saito, Y; Yasuda, K	1
Burn, J; Jonas, PA; Laffling, AJ; Lynch, SA; Pearce, MS; Relton, CL; Tawn, EJ; Wilding, CS	1
Brown, MJ; Falzone, R	1
Cheng, J; Dao, J; Zhao, R; Zhu, W	1
Isoe-Wada, K; Kowa, H; Kusumi, M; Nakashima, K; Nakaso, K; Takeshima, T; Urakami, K; Wakutani, Y; Yano, H; Yasui, K	1
Fliessbach, K; Glasmacher, A; Heun, R; Klockgether, T; Kölsch, H; Linnebank, A; Linnebank, M; Pels, H; Schlegel, U; Schmidt, S; Schmidt-Wolf, IG	1
Nurk, E; Refsum, H; Tell, GS; Ueland, PM; Vollset, SE	2
Meschia, JF; Worrall, BB	1
Fowler, B; Heun, R; Jeub, M; Klockgether, T; Koch, HG; Kölsch, H; Linnebank, A; Linnebank, M; Suormala, T; Wüllner, U	1
Antoniades, C; Brown, M; Chrysohoou, C; Panagiotakos, DB; Pitsavos, C; Skoumas, J; Stefanadis, C	1
Roth, E; Szabo, T; Szamosi, T; Tomsits, E; Tordai, A	1
Garcia, A; Zanibbi, K	1
Lu, H; Sun, J; Xu, Y; Xue, J; Zhu, Y	1
Cole, DE; D'Mello, N; Delgado, DH; Evrovski, J; Langman, LJ; Miner, SE; Miriuka, SG; Ross, HJ; Wong, BY	1
Harbrecht, U; Hentschel, F; Heun, R; Jessen, F; Kölsch, H; Kreis, M; Linnebank, M; Lütjohann, D; Maier, W; Schulz, A; Thelen, KM; von Bergmann, K; Wüllner, U	1
Crone, J; Falger, J; Födinger, M; Huemer, C; Huemer, M; Sailer-Höck, M; Ulmer, H	1
Li, YQ; Liu, YY; Song, XW; Wang, TG; Wu, JM; Yun, HR; Zhong, ZY; Zhou, TH	1
Guilhem, S; Igor, S; Isabelle, RV	1
Bresolin, N; Comi, GP; Del Bo, R; Dominici, R; Fenoglio, C; Forloni, G; Galbiati, S; Galimberti, D; Gatti, A; Guidi, I; Lovati, C; Mariani, C; Pomati, S; Scarpini, E; Venturelli, E; Virgilio, R	1
Bertolini, S; Cortese, C; Federici, G; Gnasso, A; Irace, C; Liberatoscioli, L; Mannucci, L; Pastore, A; Pisciotta, L	1
Date, C; Lwin, H; Saito, K; Tanaka, H; Yokoyama, T; Yoshiike, N	1
Dowey, L; McNulty, H; Pentieva, K; Strain, JJ; Ward, M	1
Alikasifoglu, M; Erbas, T; Tuncbilek, E; Tutuncu, NB	1
Haldeman, S; Peerdeman, SM; Riphagen, I; Rubinstein, SM; van Tulder, MW	1
Battler, A; Harell, D; Koren-Morag, N; Mager, A; Shohat, M	1
Brenes, G; Cambronero-Gutiérrez, P; Holst-Schumacher, I; Monge-Rojas, R	1
Alvarez González, A; Delgado, P; Hernández, D; Lorenzo, V; Pérez Tamajón, L; Sánchez Alvarez, JE	1
Fernández-Ballart, J; Joven, J; Labad, A; Martorell, L; Murphy, M; Simó, JM; Valero, J; Vilella, E; Virgos, C	1
Blom, HJ; den Heijer, M; Kahn, RS; Muntjewerff, JW	1
Assmann, G; Cullen, P; Schulte, H	1
Fields, MC; Levine, SR	1
Bukowska, H; Honczarenko, K; Jastrzebska, M; Mierzecki, A; Millo, B; Torbus-Lisiecka, B	1
Bowron, A; Scott, J; Stansbie, D	1
Adjalla, CE; Candito, M; Gibelin, P; Gueánt, JL; Guéant-Rodriguez, RM; Herbeth, B; Juilliére, Y; Van Obberghen, E	1
Födinger, M; Hörl, WH; Puttinger, H; Rutkowski, B; Rutkowski, P; Strozecki, P; Tylicki, L; Tyszko, S	1
Bastagli, L; Bianchin, M; Bolondi, L; Chiappelli, M; Licastro, F; Maioli, F; Martelli, M; Montesi, F; Paola, F; Ravaglia, G; Tumini, E	1
Borlu, M; Calis, M; Dündar, M; Evereklioglu, C; Ilhan, O; Ozkul, Y; Taheri, S	1
Dávid, M; Habon, T; Keszthelyi, Z; Kovács, N; Losonczy, H; Nagy, A; Tóth, O	1
Blom, HJ; Ferrari, MD; Frants, RR; Kowa, H; Kruit, MC; Launer, LJ; Scher, AI; Terwindt, GM; van Buchem, M; van den Maagdenberg, AM; Verschuren, WM	1
Colaizzo, D; Corrao, AM; Di Girgenti, C; Grandone, E; Margaglione, M; Martinelli, P; Paladini, D; Pellegrino, M; Sardella, L; Vecchione, G; Zelante, L	1
Cleves, MA; Hobbs, CA; James, SJ; Jernigan, S; Lu, Y; Malik, S; Melnyk, S	1
Chan, JB; Chen, CP; Eikelboom, JW; Hankey, GJ; Ho, GY; Tan, SL; Wong, CR	1
Anteunis, LJ; Bots, ML; Durga, J; Kok, FJ; Schouten, EG; Verhoef, P	1
Hernández Ortega, E; Hernández Trujillo, Y; Macías Reyes, A; Medina, A; Rodríguez Esparragón, F; Rodríguez Pérez, JC	1
Camps, J; Fernández-Ballart, J; Ferré, N; Joven, J; Mackness, B; Mackness, M; Marsillach, J; Murphy, MM	1
Amato, S; Bottini, F; Calevo, MG; Celle, ME; Cerone, R; Di Pasquale, D; Minniti, G; Molinari, AC; Montaldi, L; Veneselli, E	1
Blom, HJ; den Heijer, M; Finnell, RH; Shaw, GM	1
Cho, SE; Chung, WS; Hong, KS; Shin, GJ	1
Akar, N; Deda, G; Teber, ST	1
Brenner, B; Hoffman, R; Nadir, Y	1
Lu, H; Sun, J; Xu, Y; Zhu, Y	1
Boisson, C; Candito, M; Gaucherand, P; Guéant, JL; Luton, D; Naimi, M; Rudigoz, JC; Van Obberghen, E	1
Baines, M; Davison, A; Fraser, WD; Higgins, G; Kredan, MB; Ranganath, LR; Taylor, W; Usher, J; West, C	1
Dierkes, J; Ebert, MP; Götze, T; Hoffmann, J; Malfertheiner, P; Röcken, C; Röhl, FW; Westphal, S; Wex, T	1
Cabral-Filho, JE; Cavalcanti, MN; D'Almeida, V; da Silva, VC; de Brito-Marques, PR; Freitas, EM; Muniz, MT; Ramos, FJ	1
Allen, RA; Dunn, ST; Eichner, JE; Kebert, CB; Moore, WE; Schechter, E; Vogel, S; Yaoi, T	1
Alfthan, G; Erlund, I; Happonen, P; Kaplan, GA; Kauhanen, J; Korhonen, M; Mosher, MJ; Mursu, J; North, KE; Salonen, JT; Tiihonen, J; Tuomainen, TP; Virtanen, JK; Voutilainen, S	1
Dhillon, VS; Husain, SA; Shahid, M	1
Carella, A; de Tommaso, M; Dicuonzo, F; Difruscolo, O; Lamberti, P; Livrea, P; Losito, L; Pietrapertosa, A; Santeramo, MT; Sardaro, M; Serpino, C	1
Klein, RD	1
Akoglu, B; Caspary, WF; Faust, D; Kindl, P; Trojan, J; Weber, N	1
Jain, S; Khullar, M; Kumari, S; Markan, S; Sachdeva, M; Sehrawat, BS	1
Archetti, S; Borroni, B; Cesana, BM; Ferrari, M; Padovani, A	1
Brown, KS; Jensen, LE; Morthala, S; Nackos, E; Von Feldt, JM; Whitehead, AS	1
Bleich, S; Frieling, H; Hillemacher, T; Kornhuber, J; von Ahsen, N; Wilhelm, J	1
Blom, HJ; den Heijer, M; Gellekink, H	1
Garanty-Bogacka, B; Gebala, A; Goral, J; Krupa, B; Syrenicz, M; Szołomicka-Kurzawa, P	1
Varga, E	1
Alroy, S; Amir, O; Barzilai, M; Cassel, A; Flugelman, MY; Halon, DA; Lavie, L; Lewis, BS; Preis, M	1
Bottiglieri, T; Caffalette, CA; Freudenreich, O; Goff, DC; Halsted, CH; Henderson, DC; Purcell, S; Roffman, JL; Weiss, AP; Wong, DH	1
Alonso, E; Arauz, A; Cantú, C; Fernández, Mde L; García, I; Hoyos, L; Jara, A; Martínez, L	1
Acín, S; Arbonés-Mainar, JM; Arnal, C; Blanco-Vaca, F; Carnicer, R; Maeda, N; Navarro, MA; Osada, J; Sarría, A; Surra, JC	1
Cabrera-Bueno, F; de Teresa-Galván, E; Espinosa-Caliani, S; García-Pinilla, JM; Gómez-Doblas, JJ; Jiménez-Navarro, M; Reyes-Engel, A	1
Arai, H; Egashira, T; Hattori, H; Horibe, H; Ishikawa, Y; Itakura, H; Kita, T; Mabuchi, H; Matsuzawa, Y; Nakaya, N; Oikawa, S; Ouchi, Y; Saito, Y; Sasaki, J; Teramoto, T; Yamada, N; Yamamoto, A	1
Kim, KW; Kim, YS; Oh, SY; Shin, BS	1
Adamiak, A; Bogusiewicz, M; Haczyński, J; Jakimiuk, AJ; Miotła, P; Rechberger, T; Skorupski, P	1
Ananth, CV; De Marco, C; Elsasser, DA; Getahun, D; Peltier, MR; Rozen, R; Smulian, JC	1
Wang, W; Wang, Xy; Xie, W	1
Lin, JJ; Lin, SZ; Liu, CS; Liu, JT; Yueh, KC	1
Fermo, I; Lattuada, G; Luzi, L; Senesi, P; Terruzzi, I	1
Alam, MA; Chauhan, SS; Husain, SA; Kabra, M; Narang, R; Vasisht, S	1
Abdelmouttaleb, I; Amouzou, EK; Barraud, H; Bigard, MA; Bronowicki, JP; Chabi, N; Guéant, JL; Halfon, P; Khiri, H; Le Faou, A; Peyrin-Biroulet, L; Sanni, A; Venard, V	1
Archetti, S; Assanelli, D; Grassi, M; Kisialiou, A; Mozzini, C; Pezzini, A	1
Gialeraki, A; Komporozos, C; Kremastinos, DT; Lekakis, I; Pavlakis, G; Rallidis, LS; Travlou, A; Vavoulis, P	1
Bi, XH; Zhang, JW; Zhang, ZX; Zhao, HL	1
Blom, HJ; Cannegieter, SC; Christiansen, SC; Hammerstrøm, J; Naess, IA; Romundstad, PR; Rosendaal, FR	1
Benyamina, A; Debuire, B; Karila, L; Lemoine, A; Marill, C; Pham, P; Reffas, M; Reynaud, M; Saffroy, R	1
Phadke, SR	1
Geisel, J; Hentschel, B; Herrmann, W; Kuntze, T; Rassoul, F; Richter, V	1
Hoey, L; McNulty, H; Pentieva, K; Ward, M	1
Brouns, R; Hop, W; Lindemans, J; Pluijm, S; Steegers, E; Steegers-Theunissen, R; Ursem, N	1
O'Brien, JT; Teper, E	1
Aydintuğ, OT; Duman, T; Düzgün, N; Ertuğrul, E; Köse, K; Morris, Y; Tutkak, H	1
Bóveda, MD; Castiñeiras, DE; Corrales, FJ; Couce, ML; Fraga, JM; Mora, MI; Mudd, SH	1
Kang, SS; Wong, PW	1
Connelly, PW; Hegele, RA; Tully, C; Young, TK	1
Rozen, R	2
Fletcher, O; Kessling, AM	1
Akar, E; Akar, N; Avcu, F; Cin, S; Misirlioğlu, M; Yalçin, A	1
Blair, AJ; Dumenco, LL; Sweeney, JD	1
Arroliga, AC; Marelich, GP; Matthay, RA; Murin, S	1
Alatri, A; Franchi, F; Moia, M	1
Cattaneo, M; Lecchi, A; Lombardi, R; Zighetti, ML	1
Boer, J; Kolbach, DN	1
Assanelli, D; Bersatti, F; Bollani, G; Cattaneo, M; Ferrari, M; Ferrari, R; Visioli, O; Zighetti, ML	1
Alikaşifoğlu, M; Anar, B; Boduroğlu, K; Tunçbilek, E	1
Bostom, AG; Selhub, J	1
Beilby, JP; Hung, J; McQuillan, BM; Nidorf, M; Thompson, PL	1
Alders, D; de Jong, SC; Jakobs, C; Kostense, PJ; Pals, G; Rauwerda, JA; Stehouwer, CD; van den Berg, M	1
Gardemann, A; Haberbosch, W; Hehrlein, FW; Katz, N; Philipp, M; Tillmanns, H; Weidemann, H	1
Donnelly, JG; Rock, GA	1
Auberger, K; Homberger, A; Junker, R; Koch, HG; Linnebank, M; Nabel, P; Nowak-Göttl, U; Schobess, R	1
King, IB; Mahomed, K; Malinow, MR; Rajkovic, A; Rozen, R; Williams, MA	1
Alagratnam, D; Swaminathan, R; Turner, C; Wickramasinghe, SN; Wierzbicki, AS	1
Law, MR; Wald, NJ	1
Coppola, A; Di Minno, G; Mancini, FP; Margaglione, M	1
Donnelly, JG; Isotalo, PA; Wells, GA	1
Burlina, AB; Cesari, M; Narkiewicz, K; Rossi, GP; Sacchetto, A; Sartori, MT	1
Blom, HJ	1
Cerbone, AM; Coppola, A; Davi, G; De Stefano, V; Di Minno, G; Mancini, FP	1
Boers, GH; Naughten, ER; Wilcken, B; Wilcken, DE; Yap, S	1
Ben-Yehuda, A; Friedlander, Y; Friedman, G; Goldschmidt, N; Raz, I; Shpichinetsky, V; Wexler, ID	1
Ho, CH	1
Bridge, PJ; Fick, G; Hyndman, ME; Parsons, HG; Warnica, JW	1
Günther, G; Heller, C; Junker, R; Kreuz, W; Kurnik, K; Nowak-Göttl, U; Schobess, R	1
Kluijtmans, LA; Whitehead, AS	1
Chen, J; Hennekens, CH; Hunter, DJ; Ma, J; Malinow, MR; Selhub, J; Stampfer, MJ	1
Billett, HH; Estrada, DA	1
Kirkham, F; Krywawych, S; Liesner, R; Prengler, M; Sturt, N; Surtees, R	1
Axenti, I; Brzostek, T; Czachór, R; Dropiński, J; Jankowski, M; Musiał, J; Sanak, M; Szczeklik, A; Tendera, M; Twardowska, M	1
Barbaux, S; Evans, A; Gaughan, DJ; Kluijtmans, LA; McMaster, D; Whitehead, AS; Yarnell, JW; Young, IS	1
Chen, Y; Wang, J; Wang, L; Xue, Y; Zou, H	1
Dai, C; Zhang, G	1
Barlera, S; Chiodini, BD; Franzosi, MG; Tognoni, G	1
Blom, HJ; Boers, GH; den Heijer, M; Kluijtmans, LA; Lievers, KJ; Trijbels, FJ; van der Put, NM; Verhoef, P	1
Sun, J; Xu, Y; Zhu, Y	1
Finnell, RH; Gelineau-van Waes, J; Le, CX; Lu, X; Spiegelstein, O; Vorce, RL; Wlodarczyk, B	1
Danese, S; Gasbarrini, A; Gasbarrini, G; Papa, A	1
Cerbone, AM; Cirillo, F; Coppola, A; de Stefano, V; Di Minno, G; Madonna, P; Orefice, G	1
Duff, GW; Kornman, KS	1
Bellet, H; Bounameaux, H; Daurès, JP; Dauzat, M; de Moerloose, P; Gris, JC; Janbon, C; Laroche, JP; Mercier, E; Perneger, TV; Quéré, I; Schved, JF; Zittoun, J	1
Huang, Y; Li, S; Zhao Yl, Yl	1
Bukowska, H; Chelstowski, K; Honczarenko, K; Jastrzebska, M; Naruszewicz, M; Torbus-Lisiecka, B	1

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67 review(s) available for homocysteine and Genetic Predisposition

Article	Year
Evidence on the causal link between homocysteine and hypertension from a meta-analysis of 40 173 individuals implementing Mendelian randomization. Journal of clinical hypertension (Greenwich, Conn.), 2019, Volume: 21, Issue:12 Topics: Case-Control Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hypertension; Male; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors	2019
The role of DNA methylation in coronary artery disease. Gene, 2018, Mar-10, Volume: 646 Topics: Alu Elements; Animals; Coronary Artery Disease; DNA Methylation; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Long Interspersed Nucleotide Elements; Male; Sequence Analysis, DNA	2018
Analytic Approaches for the Treatment of Hyperhomocysteinemia and Its Impact on Vascular Disease. Cardiovascular drugs and therapy, 2018, Volume: 32, Issue:2 Topics: Animals; Betaine; Biomarkers; Cardiovascular Diseases; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Phenotype; Risk Factors; Tetrahydrofolates; Treatment Outcome	2018
An evidence-based approach to globally assess the covariate-dependent effect of the MTHFR single nucleotide polymorphism rs1801133 on blood homocysteine: a systematic review and meta-analysis. The American journal of clinical nutrition, 2018, 05-01, Volume: 107, Issue:5 Topics: Evidence-Based Practice; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide	2018
Targeting MTHFR for the treatment of migraines. Expert opinion on therapeutic targets, 2019, Volume: 23, Issue:1 Topics: Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Migraine Disorders; Molecular Targeted Therapy; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6	2019
Disturbed homocysteine metabolism is associated with cancer. Experimental & molecular medicine, 2019, 02-21, Volume: 51, Issue:2 Topics: Alleles; Animals; Cystathionine beta-Synthase; Disease Susceptibility; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Metabolic Networks and Pathways; Neoplasms; Polymorphism, Genetic; Risk Factors; Sulfur; Thromboembolism	2019
The role of one-carbon metabolism and homocysteine in Parkinson's disease onset, pathology and mechanisms. Nutrition research reviews, 2019, Volume: 32, Issue:2 Topics: Animals; Diet; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Levodopa; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; One-Carbon Group Transferases; Parkinson Disease; Polymorphism, Genetic; Vitamin B Complex	2019
The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation. Atherosclerosis, 2013, Volume: 228, Issue:2 Topics: Animals; Aortic Aneurysm, Abdominal; Biomarkers; DNA Methylation; Epigenesis, Genetic; Genetic Predisposition to Disease; Genetic Therapy; Histones; Homocysteine; Humans; Phenotype; Prognosis; Risk Factors; Up-Regulation	2013
Biomarkers for incident CKD: a new framework for interpreting the literature. Nature reviews. Nephrology, 2013, Volume: 9, Issue:8 Topics: Acute-Phase Proteins; Aldosterone; Biomarkers; Connective Tissue Growth Factor; Creatinine; Cystatin C; Genetic Markers; Genetic Predisposition to Disease; Glomerular Filtration Rate; Hepatitis A Virus Cellular Receptor 1; Homocysteine; Humans; Lipocalin-2; Lipocalins; Membrane Glycoproteins; Peptides; Proto-Oncogene Proteins; Receptors, Virus; Renal Insufficiency, Chronic; Risk Factors; Transforming Growth Factor beta; Trefoil Factor-3; Uromodulin	2013
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. The American journal of clinical nutrition, 2013, Volume: 98, Issue:3 Topics: Coronary Artery Disease; Genes; Genetic Loci; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Polymorphism, Genetic; Risk Factors	2013
Association of homocysteine with type 2 diabetes: a meta-analysis implementing Mendelian randomization approach. BMC genomics, 2013, Dec-10, Volume: 14 Topics: Alleles; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors	2013
[Reconsideration of homocysteinemia]. Seikagaku. The Journal of Japanese Biochemical Society, 2013, Volume: 85, Issue:12 Topics: Animals; Disease Models, Animal; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Sulfhydryl Compounds	2013
The MTRR 66A>G polymorphism and maternal risk of birth of a child with Down syndrome in Caucasian women: a case-control study and a meta-analysis. Molecular biology reports, 2014, Volume: 41, Issue:9 Topics: Adult; Aged; Alleles; Biomarkers; Case-Control Studies; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Genotyping Techniques; Heterozygote; Homocysteine; Humans; Logistic Models; Middle Aged; Mothers; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12; White People	2014
"Polymorphisms in folate metabolism genes as maternal risk factor for neural tube defects: an updated meta-analysis". Metabolic brain disease, 2015, Volume: 30, Issue:1 Topics: Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Odds Ratio; Polymorphism, Single Nucleotide; Pregnancy; Publication Bias; Risk Factors	2015
Methylenetetrahydrofolate reductase C677T polymorphism, venous thrombosis, cardiovascular risk, and other effects. Angiology, 2015, Volume: 66, Issue:5 Topics: Animals; Biomarkers; Comorbidity; Dietary Supplements; Gene Frequency; Genetic Predisposition to Disease; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Methylenetetrahydrofolate Reductase (NADPH2); Phenotype; Polymorphism, Genetic; Risk Assessment; Risk Factors; Treatment Outcome; Venous Thromboembolism; Vitamin B Complex	2015
Genome-wide association study of selenium concentrations. Human molecular genetics, 2015, Mar-01, Volume: 24, Issue:5 Topics: Coronary Artery Disease; Genetic Loci; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Genotyping Techniques; Homocysteine; Humans; Nails; Polymorphism, Single Nucleotide; Selenium; Selenoproteins; Thioredoxin Reductase 1	2015
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: epidemiology, metabolism and the associated diseases. European journal of medical genetics, 2015, Volume: 58, Issue:1 Topics: Diabetes Mellitus; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Infertility; Mental Disorders; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Nervous System Diseases; Polymorphism, Genetic; Psoriasis; Vascular Diseases; Vitamin B 12	2015
Association of MTHFR C677T with total homocysteine plasma levels and susceptibility to Parkinson's disease: a meta-analysis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36, Issue:6 Topics: Asian People; China; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Parkinson Disease; Polymorphism, Single Nucleotide; Risk Factors; White People	2015
Matrix metalloproteinases in atherosclerosis: role of nitric oxide, hydrogen sulfide, homocysteine, and polymorphisms. Vascular health and risk management, 2015, Volume: 11 Topics: Animals; Atherosclerosis; Blood Vessels; Enzyme Activation; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrogen Sulfide; Matrix Metalloproteinases; Nitric Oxide; Oxidative Stress; Phenotype; Polymorphism, Genetic; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling; Vasodilation	2015
Genetic polymorphism of MTHFR C677T and premature coronary artery disease susceptibility: A meta-analysis. Gene, 2015, Jul-01, Volume: 565, Issue:1 Topics: Adult; Asian People; China; Coronary Artery Disease; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Publication Bias; Young Adult	2015
Evaluation of an association between plasma total homocysteine and schizophrenia by a Mendelian randomization analysis. BMC medical genetics, 2015, Jul-26, Volume: 16 Topics: Case-Control Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Risk Factors; Schizophrenia	2015
Association between eNOS polymorphisms and risk of coronary artery disease in a Korean population: a meta-analysis. Genetics and molecular research : GMR, 2015, Dec-09, Volume: 14, Issue:4 Topics: Aged; Alleles; Asian People; Case-Control Studies; Comorbidity; Coronary Artery Disease; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Haplotypes; Homocysteine; Humans; Linkage Disequilibrium; Male; Middle Aged; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Republic of Korea; Risk; Risk Factors	2015
Homocysteine and Alzheimer's Disease: Evidence for a Causal Link from Mendelian Randomization. Journal of Alzheimer's disease : JAD, 2016, 03-22, Volume: 52, Issue:2 Topics: Alzheimer Disease; Data Interpretation, Statistical; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide	2016
Clinical utility of folate pathway genetic polymorphisms in the diagnosis of autism spectrum disorders. Psychiatric genetics, 2016, Volume: 26, Issue:6 Topics: Alleles; Autism Spectrum Disorder; Autistic Disorder; Child; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors	2016
Exfoliation syndrome: beyond glaucoma. Archives of ophthalmology (Chicago, Ill. : 1960), 2008, Volume: 126, Issue:6 Topics: Amino Acid Oxidoreductases; Elastic Tissue; Exfoliation Syndrome; Genetic Predisposition to Disease; Glaucoma; Homocysteine; Humans; Ischemia; Mutation; Protein-Lysine 6-Oxidase; Risk Factors; Transforming Growth Factor beta1	2008
Murine models of hyperhomocysteinemia and their vascular phenotypes. Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:9 Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Genetic Predisposition to Disease; Homocysteine; Hyperhomocysteinemia; Mice; Phenotype; Thrombosis	2008
Hyperhomocysteinemia: no longer a consideration in the management of venous thromboembolism. Current opinion in pulmonary medicine, 2008, Volume: 14, Issue:5 Topics: Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Polymorphism, Genetic; Risk Factors; Venous Thromboembolism	2008
The worldwide challenge of the dementias: a role for B vitamins and homocysteine? Food and nutrition bulletin, 2008, Volume: 29, Issue:2 Suppl Topics: Aged; Aged, 80 and over; Aging; Dementia; Environment; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B Complex	2008
Homocysteine and depression in later life. Archives of general psychiatry, 2008, Volume: 65, Issue:11 Topics: Age Factors; Aged; Cohort Studies; Depressive Disorder; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Personality Inventory; Polymorphism, Genetic; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12	2008
Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis. Journal of vascular surgery, 2009, Volume: 49, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cross-Sectional Studies; England; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multicenter Studies as Topic; Mutation; Odds Ratio; Peripheral Vascular Diseases; Phenotype; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Risk Assessment	2009
The search for genetic polymorphisms in the homocysteine/folate pathway that contribute to the etiology of human neural tube defects. Birth defects research. Part A, Clinical and molecular teratology, 2009, Volume: 85, Issue:4 Topics: Clinical Trials as Topic; DNA Mutational Analysis; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Metabolic Networks and Pathways; Models, Biological; Neural Tube Defects; Polymorphism, Genetic; Pregnancy; Research	2009
Gene polymorphisms and risk of adult early-onset ischemic stroke: A meta-analysis. Thrombosis research, 2009, Volume: 124, Issue:5 Topics: Adolescent; Adult; Apolipoproteins E; Case-Control Studies; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Lipid Metabolism; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Stroke; Young Adult	2009
[The role of methylation processes in etiology and pathogenesis of schizophrenia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2009, Volume: 109, Issue:8 Topics: DNA; Genetic Predisposition to Disease; Homocysteine; Humans; Methylation; Receptors, Dopamine; Schizophrenia	2009
Polymorphism of genes encoding homocysteine metabolism-related enzymes and risk for cardiovascular disease. Nutrition research (New York, N.Y.), 2009, Volume: 29, Issue:10 Topics: Cardiovascular Diseases; Enzymes; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Physiological Phenomena; Polymorphism, Genetic; Risk Factors; Vitamins	2009
Postgraduate Symposium: The MTHFR C677T polymorphism, B-vitamins and blood pressure. The Proceedings of the Nutrition Society, 2010, Volume: 69, Issue:1 Topics: Blood Pressure; Clinical Trials as Topic; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Hypertension; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Riboflavin; Risk Factors; Stroke; Vitamin B Complex	2010
Genetic and epigenetic mechanisms and their possible role in abdominal aortic aneurysm. Atherosclerosis, 2010, Volume: 212, Issue:1 Topics: Acetylation; Age Factors; Aortic Aneurysm, Abdominal; Chromatin Assembly and Disassembly; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Histone Deacetylase Inhibitors; Histones; Homocysteine; Humans; Inflammation; Male; Oligonucleotides, Antisense; Peptide Hydrolases; Risk Assessment; Risk Factors; Smoking	2010
Comorbidity, multimorbidity and personalized psychosomatic medicine: epigenetics rolling on the horizon. Psychiatria Danubina, 2010, Volume: 22, Issue:2 Topics: Character; Comorbidity; DNA Damage; Epigenesis, Genetic; Gene Expression Regulation; Genetic Predisposition to Disease; Homocysteine; Humans; Mental Disorders; Mind-Body Relations, Metaphysical; Nerve Net; Phenotype; Psychophysiologic Disorders; Risk Factors	2010
[Genes involved in folate metabolim and neural tube defects]. Zhonghua fu chan ke za zhi, 2011, Volume: 46, Issue:4 Topics: Female; Folic Acid; Folic Acid Transporters; Genetic Predisposition to Disease; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Single Nucleotide; Pregnancy; Reduced Folate Carrier Protein; Risk Factors	2011
Three genetic polymorphisms of homocysteine-metabolizing enzymes and risk of coronary heart disease: a meta-analysis based on 23 case-control studies. DNA and cell biology, 2012, Volume: 31, Issue:2 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Algorithms; Case-Control Studies; Coronary Disease; Ferredoxin-NADP Reductase; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Review Literature as Topic; Risk Factors; White People	2012
C(1) metabolism and CVD outcomes in older adults. The Proceedings of the Nutrition Society, 2012, Volume: 71, Issue:2 Topics: Blood Pressure; Carbon; Cardiovascular Diseases; Folic Acid; Genetic Predisposition to Disease; Genotype; Heart Diseases; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Riboflavin; Stroke; Vitamin B Complex	2012
Folate-genetics and colorectal neoplasia: what we know and need to know next. Molecular nutrition & food research, 2013, Volume: 57, Issue:4 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Colorectal Neoplasms; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Randomized Controlled Trials as Topic; Risk Factors; S-Adenosylmethionine; Thymidylate Synthase	2013
Homocysteine, MTHFR 677C-->T polymorphism, and risk of ischemic stroke: results of a meta-analysis. Neurology, 2002, Aug-27, Volume: 59, Issue:4 Topics: Brain Ischemia; Case-Control Studies; Cohort Studies; Comorbidity; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prevalence; Prospective Studies; Retrospective Studies; Risk Assessment; Stroke	2002
Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ (Clinical research ed.), 2002, Nov-23, Volume: 325, Issue:7374 Topics: Cohort Studies; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Myocardial Ischemia; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Prospective Studies; Pulmonary Embolism; Risk Factors; Venous Thrombosis	2002
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data]. Pathologie-biologie, 2003, Volume: 51, Issue:2 Topics: Animals; Arteriosclerosis; Biomarkers; Cystathionine beta-Synthase; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Nitric Oxide; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Rats; Risk Factors; S-Adenosylmethionine; Signal Transduction; Thrombophilia; Vascular Diseases; Vasodilation; Vitamin B 6 Deficiency	2003
Homocysteine and cognitive function in elderly people. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Oct-12, Volume: 171, Issue:8 Topics: Aged; Aged, 80 and over; Cognition Disorders; Dementia; Genetic Predisposition to Disease; Homocysteine; Humans; Middle Aged; Risk Factors; Vitamin B Complex	2004
B-vitamins, homocysteine metabolism and CVD. The Proceedings of the Nutrition Society, 2004, Volume: 63, Issue:4 Topics: Carbon-Nitrogen Ligases; Cardiovascular Diseases; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Polymorphism, Genetic; Risk Factors; Vitamin B Complex; Vitamin B Deficiency	2004
A systematic review of the risk factors for cervical artery dissection. Stroke, 2005, Volume: 36, Issue:7 Topics: Adult; Aged; alpha 1-Antitrypsin; Aorta; Atherosclerosis; Carotid Artery, Common; Carotid Artery, Internal, Dissection; Case-Control Studies; Cohort Studies; Environmental Exposure; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Middle Aged; Migraine Disorders; Mutation; Odds Ratio; Polymorphism, Genetic; Risk; Risk Factors; Sequence Analysis, DNA; Vertebral Artery Dissection; Wounds and Injuries	2005
Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis. Molecular psychiatry, 2006, Volume: 11, Issue:2 Topics: Amino Acid Substitution; Case-Control Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Reference Values; Risk Factors; Schizophrenia	2006
Interleukin-1beta and interleukin-6 gene polymorphisms as risk factors for AD: a prospective study. Experimental gerontology, 2006, Volume: 41, Issue:1 Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Dementia; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Interleukin-1; Interleukin-6; Male; Polymorphism, Genetic; Prospective Studies; Risk Factors	2006
[Type I antithrombin deficiency as a cause of arterial and venous thrombosis in a family with severe thrombophilia]. Orvosi hetilap, 2005, Oct-09, Volume: 146, Issue:41 Topics: Adult; C-Reactive Protein; Cholesterol; Cysteine; Female; Fibrin; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Pedigree; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Risk Factors; Threonine; Thrombophilia; Thrombosis; Venous Thrombosis; von Willebrand Factor	2005
[Concerning the significance of paraoxonase-1 and SR-B1 genes in atherosclerosis]. Revista espanola de cardiologia, 2006, Volume: 59, Issue:2 Topics: Animals; Anticholesteremic Agents; Aryldialkylphosphatase; Atherosclerosis; Cardiovascular Diseases; Cholesterol; Cholesterol Esters; Disease Models, Animal; Genetic Predisposition to Disease; Homocysteine; Humans; Lipid Metabolism; Lipoproteins, HDL; Lipoproteins, LDL; Male; Mice; Mice, Transgenic; Oxidative Stress; Phenotype; Polymorphism, Genetic; Receptors, Lipoprotein; Scavenger Receptors, Class B	2006
Neural tube defects and folate: case far from closed. Nature reviews. Neuroscience, 2006, Volume: 7, Issue:9 Topics: Animals; Central Nervous System; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects	2006
Inherited thrombophilia: key points for genetic counseling. Journal of genetic counseling, 2007, Volume: 16, Issue:3 Topics: Abortion, Habitual; Antithrombin III Deficiency; Factor V; Female; Genetic Counseling; Genetic Predisposition to Disease; Genetic Testing; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Prothrombin; Referral and Consultation; Risk Assessment; Thromboembolism; Thrombophilia	2007
Homocysteine, B-vitamins and CVD. The Proceedings of the Nutrition Society, 2008, Volume: 67, Issue:2 Topics: Cardiovascular Diseases; Folic Acid; Food, Fortified; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Nutrition Policy; Nutritional Status; Polymorphism, Genetic; Vitamin B Complex	2008
Vascular factors and depression. International journal of geriatric psychiatry, 2008, Volume: 23, Issue:10 Topics: Autonomic Nervous System; Biomarkers; Cytokines; Depression; Endothelium, Vascular; Fatty Acids, Omega-3; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrocortisone; Risk Factors; Vascular Diseases	2008
Genetic and nongenetic factors for moderate hyperhomocyst(e)inemia. Atherosclerosis, 1996, Jan-26, Volume: 119, Issue:2 Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine beta-Synthase; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Phenotype; Prevalence; Risk Factors; Vascular Diseases	1996
Genetic predisposition to hyperhomocysteinemia: deficiency of methylenetetrahydrofolate reductase (MTHFR). Thrombosis and haemostasis, 1997, Volume: 78, Issue:1 Topics: Cardiovascular Diseases; Genetic Predisposition to Disease; Genetic Variation; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Risk Factors	1997
MTHFR association with arteriosclerotic vascular disease? Human genetics, 1998, Volume: 103, Issue:1 Topics: Alleles; Arteriosclerosis; Databases, Bibliographic; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; MEDLINE; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation	1998
Hereditary thrombophilia and venous thromboembolism. American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:5 Pt 1 Topics: Antithrombin III Deficiency; Factor V; Genetic Predisposition to Disease; Homocysteine; Humans; Mutation; Prevalence; Protein C; Protein C Deficiency; Protein S Deficiency; Prothrombin; Thrombophilia; Venous Thrombosis	1998
Homocysteine and ischaemic heart disease. Haematologica, 1999, Volume: 84 Suppl EHA-4 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Cohort Studies; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Ischemia; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Retrospective Studies	1999
Homocysteine, platelet function and thrombosis. Haematologica, 1999, Volume: 84 Suppl EHA-4 Topics: Arterial Occlusive Diseases; Blood Coagulation Factors; Blood Platelets; Comorbidity; Endothelium, Vascular; Fibrinolysis; Free Radicals; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Nitric Oxide; Oxidative Stress; Thrombin; Thrombomodulin; Thrombophilia; Thromboxane A2	1999
Consequences of homocysteine export and oxidation in the vascular system. Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:3 Topics: Arteriosclerosis; Blood Cells; Cardiovascular System; Disulfides; Endothelium, Vascular; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Liver; Oxidation-Reduction; Thrombophilia	2000
Homocysteine, coagulation, platelet function, and thrombosis. Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:3 Topics: Adolescent; Adult; Arteriosclerosis; Blood Coagulation; Cardiovascular Diseases; Cellular Senescence; Child; Endothelium, Vascular; Female; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Lipoproteins, LDL; Male; Methyltransferases; Oxidation-Reduction; Platelet Activation; Reactive Oxygen Species; Renal Insufficiency; Risk Factors; S-Adenosylhomocysteine; Thrombophilia; Thromboxane B2; Vitamin K	2000
Genetic modulation of homocysteinemia. Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:3 Topics: Amino Acid Substitution; Cardiovascular Diseases; Cystathionine beta-Synthase; Cysteine; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methyltransferases; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Sulfur; Tetrahydrofolates	2000
Vascular complications of severe hyperhomocysteinemia in patients with homocystinuria due to cystathionine beta-synthase deficiency: effects of homocysteine-lowering therapy. Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:3 Topics: Adolescent; Adult; Aged; Australia; Child; Child, Preschool; Cohort Studies; Cystine; Drug Resistance; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Ireland; Male; Methionine; Middle Aged; Netherlands; Pyridoxine; Risk; Risk Factors; Thrombophilia; Vascular Diseases; Vitamin B 12	2000
[Susceptibility gene to infarct: a review of the literature]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2001, Volume: 2, Issue:9 Topics: Case-Control Studies; Genetic Predisposition to Disease; Hemostasis; Homocysteine; Humans; Lipid Metabolism; Myocardial Infarction; Renin-Angiotensin System	2001
Candidate genes as potential links between periodontal and cardiovascular diseases. Annals of periodontology, 2001, Volume: 6, Issue:1 Topics: Alleles; Blood Coagulation Factors; Cardiovascular Diseases; Chronic Disease; Environment; Genes; Genetic Markers; Genetic Predisposition to Disease; Genetic Variation; Genotype; Homocysteine; Humans; Immunologic Factors; Inflammation; Interleukin-1; Lipids; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Periodontitis; Polymorphism, Genetic; Risk Factors; Wound Healing	2001

Trials

13 trial(s) available for homocysteine and Genetic Predisposition

Article	Year
Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: th Pharmacogenetics and genomics, 2008, Volume: 18, Issue:8 Topics: Aged; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Kaplan-Meier Estimate; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Treatment Outcome	2008
Maternal one-carbon metabolism, MTHFR and TCN2 genotypes and neural tube defects in India. Birth defects research. Part A, Clinical and molecular teratology, 2011, Volume: 91, Issue:9 Topics: Adult; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; India; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency	2011
Gene-nutrient and gene-gene interactions of controlled folate intake by Japanese women. Biochemical and biophysical research communications, 2004, Apr-16, Volume: 316, Issue:4 Topics: Adult; Cardiovascular Diseases; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Testing; Homocysteine; Humans; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Women's Health	2004
Influence of the Glu298Asp polymorphism of NOS3 on age at onset and homocysteine levels in AD patients. Neurobiology of aging, 2005, Volume: 26, Issue:6 Topics: Age Distribution; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Substitution; Female; Genetic Predisposition to Disease; Genetic Testing; Glutamine; Homocysteine; Humans; Italy; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Risk Assessment; Risk Factors; Statistics as Topic	2005
[Efficacy and safety of two vitamin supplement regimens on homocysteine levels in hemodialysis patients. Prospective, randomized clinical trial]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2005, Volume: 25, Issue:3 Topics: Aged; Aged, 80 and over; Cohort Studies; Diabetic Nephropathies; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B 6	2005
Methylenetetrahydrofolate reductase polymorphisms and homocysteine-lowering effect of vitamin therapy in Singaporean stroke patients. Stroke, 2006, Volume: 37, Issue:2 Topics: Aged; Coronary Artery Disease; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Middle Aged; Models, Statistical; Placebos; Polymorphism, Genetic; Regression Analysis; Risk Factors; Singapore; Stroke; Vitamin B 12; Vitamin B 6; Vitamins	2006
Association of folate with hearing is dependent on the 5,10-methylenetetrahdyrofolate reductase 677C-->T mutation. Neurobiology of aging, 2006, Volume: 27, Issue:3 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Auditory Threshold; Female; Folic Acid; Genetic Predisposition to Disease; Hearing Loss, Sensorineural; Homocysteine; Humans; Incidence; Male; Middle Aged; Mutation; Netherlands; Polymorphism, Genetic; Risk Assessment; Risk Factors; Severity of Illness Index; Vitamin B 12	2006
Metabolic and genetic risk factors for migraine in children. Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:6 Topics: Adolescent; Child; Child, Preschool; Comorbidity; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Italy; Male; Metabolic Diseases; Methylenetetrahydrofolate Reductase (NADPH2); Migraine Disorders; Mutation; Prevalence; Risk Assessment; Risk Factors; Thrombosis	2006
MTHFR 677 CT/MTHFR 1298 CC genotypes are associated with increased risk of hypertension in Indians. Molecular and cellular biochemistry, 2007, Volume: 302, Issue:1-2 Topics: Asian People; Case-Control Studies; Cytosine; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hypertension; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Thymine	2007
Association of the 677C-->T mutation on the methylenetetrahydrofolate reductase gene in Turkish patients with neural tube defects. Journal of child neurology, 1999, Volume: 14, Issue:3 Topics: Adult; Alleles; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Turkey	1999
The TT genotype of the methylenetetrahydrofolate reductase C677T gene polymorphism is associated with the extent of coronary atherosclerosis in patients at high risk for coronary artery disease. European heart journal, 1999, Volume: 20, Issue:8 Topics: Adult; Aged; Analysis of Variance; Coronary Artery Disease; Genetic Markers; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prognosis; Risk Assessment; Risk Factors; Sensitivity and Specificity; Severity of Illness Index	1999
Serum homocysteine, folate and thermolabile variant of MTHFR in healthy Sri Lankans living in London. Atherosclerosis, 2000, Volume: 149, Issue:1 Topics: Adult; Coronary Disease; Emigration and Immigration; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Variation; Homocysteine; Humans; London; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Sri Lanka	2000
Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction. Atherosclerosis, 2001, Feb-15, Volume: 154, Issue:3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Case-Control Studies; Double-Blind Method; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; Prospective Studies	2001

Other Studies

309 other study(ies) available for homocysteine and Genetic Predisposition

Article	Year
Association of the methylenetetrahydrofolate reductase ( The Journal of international medical research, 2022, Volume: 50, Issue:2 Topics: Brain Ischemia; Case-Control Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Ischemic Stroke; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Stroke	2022
Plasma metal concentrations and their interactions with genetic susceptibility on homocysteine levels. Ecotoxicology and environmental safety, 2022, Volume: 241 Topics: Cardiovascular Diseases; Cross-Sectional Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Metals; Selenium	2022
The role of methylenetetrahydrofolate reductase C677T gene polymorphism as a risk factor for coronary artery disease: a cross-sectional study in the Sidoarjo Regional General Hospital. The Pan African medical journal, 2022, Volume: 41 Topics: Case-Control Studies; Coronary Artery Disease; Cross-Sectional Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic	2022
MTHFR SNPs (Methyl Tetrahydrofolate Reductase, Single Nucleotide Polymorphisms) C677T and A1298C Prevalence and Serum Homocysteine Levels in >2100 Hypofertile Caucasian Male Patients Biomolecules, 2022, 08-07, Volume: 12, Issue:8 Topics: Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Infertility; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Prevalence; Tetrahydrofolates	2022
Large-Scale Targeted Sequencing Study of Ischemic Stroke in the Han Chinese Population. Journal of the American Heart Association, 2022, 10-04, Volume: 11, Issue:19 Topics: Aldehyde Dehydrogenase, Mitochondrial; Asian People; Case-Control Studies; China; Genetic Predisposition to Disease; Homocysteine; Humans; Ischemic Stroke; Polymorphism, Single Nucleotide; Risk Factors; Stroke; Transcription Factors	2022
Genetic susceptibility, homocysteine levels, and risk of all-cause and cause-specific mortality: A prospective cohort study. Clinica chimica acta; international journal of clinical chemistry, 2023, Jan-01, Volume: 538 Topics: Adult; Aged; Cause of Death; Coronary Disease; Genetic Predisposition to Disease; Homocysteine; Humans; Middle Aged; Prospective Studies; Risk Factors	2023
Association Between MTHFR Gene Common Variants, Serum Homocysteine, and Risk of Early-Onset Coronary Artery Disease: A Case-Control Study. Biochemical genetics, 2020, Volume: 58, Issue:2 Topics: Adult; Case-Control Studies; China; Coronary Artery Disease; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors	2020
Genetic Association of Plasma Homocysteine Levels with Gastric Cancer Risk: A Two-Sample Mendelian Randomization Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2020, Volume: 29, Issue:2 Topics: Body Mass Index; Case-Control Studies; Causality; Datasets as Topic; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Homocysteine; Humans; Male; Mendelian Randomization Analysis; Meta-Analysis as Topic; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Stomach Neoplasms	2020
MTHFR C677T polymorphism and hypertension. Journal of clinical hypertension (Greenwich, Conn.), 2020, Volume: 22, Issue:2 Topics: Genetic Predisposition to Disease; Homocysteine; Humans; Hypertension; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic	2020
Apply multiple genetic variants as instrumental variables-Response to "MTHFR C677T polymorphism and hypertension". Journal of clinical hypertension (Greenwich, Conn.), 2020, Volume: 22, Issue:2 Topics: Genetic Predisposition to Disease; Homocysteine; Humans; Hypertension; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic	2020
Associations of MTRR A66G polymorphism and promoter methylation with ischemic stroke in patients with hyperhomocysteinemia. The journal of gene medicine, 2020, Volume: 22, Issue:5 Topics: Aged; Case-Control Studies; DNA Methylation; Female; Ferredoxin-NADP Reductase; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Stroke; Logistic Models; Male; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Factors	2020
Association of MTHFR C677T polymorphism with elevated homocysteine level and disease development in vitiligo. International journal of immunogenetics, 2020, Volume: 47, Issue:4 Topics: Adolescent; Adult; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Homozygote; Humans; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12; Vitiligo; Young Adult	2020
Serum homocysteine and risk of dementia in Japan. Journal of neurology, neurosurgery, and psychiatry, 2020, Volume: 91, Issue:5 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Dementia, Vascular; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors	2020
Identifying gene-environment interactions on the efficacy of folic acid therapy for hyperhomocysteinemia based on prediction model. Nutrition research (New York, N.Y.), 2020, Volume: 77 Topics: Aged; Algorithms; Coronary Disease; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Machine Learning; Male; Middle Aged; Models, Theoretical; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Stroke; Treatment Failure; Treatment Outcome	2020
Association of the methylene-tetrahydrofolate reductase gene rs1801133 C677T variant with serum homocysteine levels, and the severity of coronary artery disease. Scientific reports, 2020, 06-22, Volume: 10, Issue:1 Topics: Adult; Aged; Case-Control Studies; Coronary Artery Disease; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; ROC Curve; Severity of Illness Index; Tunisia; Young Adult	2020
A comprehensive evaluation of association between homocysteine levels and single nucleotide polymorphisms with hypertension risk: A protocol of systematic review and network meta-analysis. Medicine, 2020, Jun-26, Volume: 99, Issue:26 Topics: Correlation of Data; Genetic Predisposition to Disease; Homocysteine; Humans; Hypertension; Network Meta-Analysis; Polymorphism, Single Nucleotide; Research Design; Systematic Reviews as Topic	2020
The impact of homocysteine on the risk of coronary artery diseases in individuals with diabetes: a Mendelian randomization study. Acta diabetologica, 2021, Volume: 58, Issue:3 Topics: Case-Control Studies; Causality; Coronary Artery Disease; Diabetes Mellitus; Diabetic Angiopathies; Genetic Predisposition to Disease; Genome-Wide Association Study; Homocysteine; Humans; Linkage Disequilibrium; Mendelian Randomization Analysis; Meta-Analysis as Topic; Metabolic Networks and Pathways; Odds Ratio; Polymorphism, Single Nucleotide	2021
No causal association between plasma homocysteine levels and atrial fibrillation: A Mendelian randomization study. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2021, 02-08, Volume: 31, Issue:2 Topics: Atrial Fibrillation; Biomarkers; Genetic Predisposition to Disease; Genome-Wide Association Study; Homocysteine; Humans; Hyperhomocysteinemia; Mendelian Randomization Analysis; Meta-Analysis as Topic; Phenotype; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors	2021
Correlation between total homocysteine and cerebral small vessel disease: A Mendelian randomization study. European journal of neurology, 2021, Volume: 28, Issue:6 Topics: Cerebral Small Vessel Diseases; Cohort Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2)	2021
Association of three missense mutations in the homocysteine-related MTHFR and MTRR gene with risk of polycystic ovary syndrome in Southern Chinese women. Reproductive biology and endocrinology : RB&E, 2021, Jan-07, Volume: 19, Issue:1 Topics: Adult; Asian People; Case-Control Studies; China; Female; Ferredoxin-NADP Reductase; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Linkage Disequilibrium; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Risk Factors; Young Adult	2021
Rare variants in MTHFR predispose to occurrence and recurrence of pulmonary embolism. International journal of cardiology, 2021, 05-15, Volume: 331 Topics: Case-Control Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Phenotype; Pulmonary Embolism; Recurrence	2021
MTHFR (methylenetetrahydrofolate reductase: EC 1.5.1.20) SNPs (single-nucleotide polymorphisms) and homocysteine in patients referred for investigation of fertility. Journal of assisted reproduction and genetics, 2021, Volume: 38, Issue:9 Topics: Abortion, Spontaneous; Female; France; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Infertility; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Retrospective Studies	2021
Annals of clinical and laboratory science, 2021, Volume: 51, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Diagnostic Tests, Routine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide	2021
The Homocysteine and Metabolic Syndrome: A Mendelian Randomization Study. Nutrients, 2021, Jul-16, Volume: 13, Issue:7 Topics: Aged; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Mendelian Randomization Analysis; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide	2021
Associations of Homocysteine Metabolism With the Risk of Spinal Osteoarthritis Progression in Postmenopausal Women. The Journal of clinical endocrinology and metabolism, 2021, 11-19, Volume: 106, Issue:12 Topics: Aged; Alleles; Cross-Sectional Studies; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Japan; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osteoarthritis, Spine; Polymorphism, Genetic; Postmenopause; Prognosis; Risk Factors	2021
Polymorphisms in MTHFR, MS and CBS genes and premature acute myocardial infarction in a Pakistani population. Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:6 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Age of Onset; Analysis of Variance; Biomarkers; Case-Control Studies; Chi-Square Distribution; Cross-Sectional Studies; Cystathionine beta-Synthase; Female; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Infarction; Pakistan; Phenotype; Polymorphism, Single Nucleotide; Prevalence; Risk Factors; Up-Regulation; Young Adult	2016
Synergistic Effect of the Journal of diabetes research, 2017, Volume: 2017 Topics: Aged; Asian People; Brain Ischemia; Case-Control Studies; China; Diabetes Mellitus, Type 2; Epoxide Hydrolases; Female; Genetic Predisposition to Disease; Glycated Hemoglobin; Haplotypes; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk; Stroke	2017
An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida. Neuromolecular medicine, 2017, Volume: 19, Issue:2-3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Sequence; Cells, Cultured; Exons; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylation; Models, Molecular; Pregnancy; Pregnancy Complications; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Deletion; Spinal Dysraphism; Young Adult	2017
Blood lead levels, iron metabolism gene polymorphisms and homocysteine: a gene-environment interaction study. Occupational and environmental medicine, 2017, Volume: 74, Issue:12 Topics: Adult; Aged; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Iron; Lead; Male; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Transferrin	2017
A genetic variant in a homocysteine metabolic gene that increases the risk of congenital cardiac septal defects in Han Chinese populations. IUBMB life, 2017, Volume: 69, Issue:9 Topics: Alleles; Female; Gene Expression; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Heart Septal Defects; Homocysteine; Humans; Male; Polymorphism, Single Nucleotide; Risk Factors; Synaptotagmins	2017
Folate, vitamin B12, homocysteine and polymorphisms in folate metabolizing genes in children with congenital heart disease and their mothers. European journal of clinical nutrition, 2017, Volume: 71, Issue:12 Topics: Adult; Case-Control Studies; Child; Child, Preschool; Ferredoxin-NADP Reductase; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Heart Defects, Congenital; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Polymorphism, Single Nucleotide; Risk Factors; Socioeconomic Factors; Vitamin B 12; Young Adult	2017
Genetic influence of plasma homocysteine on Alzheimer's disease. Neurobiology of aging, 2018, Volume: 62 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Atrophy; Cognitive Dysfunction; Female; Genetic Association Studies; Genetic Predisposition to Disease; Gray Matter; Homocysteine; Humans; Male; Multifactorial Inheritance; Risk Factors; tau Proteins; White People	2018
Neuro-fuzzy model of homocysteine metabolism. Journal of genetics, 2017, Volume: 96, Issue:6 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Asian People; Chromatography, High Pressure Liquid; Female; Ferredoxin-NADP Reductase; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Models, Theoretical; Polymorphism, Single Nucleotide; Thymidylate Synthase	2017
Genome-wide association study of homocysteine in African Americans from the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Coronary Artery Risk in Young Adults study. Journal of human genetics, 2018, Volume: 63, Issue:3 Topics: Adult; Alleles; Atherosclerosis; Black or African American; Coronary Artery Disease; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Mississippi; Polymorphism, Single Nucleotide; Population Surveillance; Quantitative Trait Loci; Quantitative Trait, Heritable; Young Adult	2018
Association of elevated homocysteine levels and Methylenetetrahydrofolate reductase (MTHFR) 1298 A > C polymorphism with Vitiligo susceptibility in Gujarat. Journal of dermatological science, 2018, Volume: 90, Issue:2 Topics: Adolescent; Adult; Case-Control Studies; Child; Computer Simulation; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Vitamin B 12; Vitiligo; Young Adult	2018
Serum homocysteine, arsenic methylation, and arsenic-induced skin lesion incidence in Bangladesh: A one-carbon metabolism candidate gene study. Environment international, 2018, Volume: 113 Topics: Arsenic; Arsenicals; Bangladesh; Case-Control Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Methylation; Polymorphism, Single Nucleotide; Skin Diseases	2018
Selected risk factors for atherosclerosis in children and their parents with positive family history of premature cardiovascular diseases: a prospective study. BMC pediatrics, 2018, 04-03, Volume: 18, Issue:1 Topics: Adult; Atherosclerosis; Biomarkers; Carotid Intima-Media Thickness; Cell Adhesion Molecules; Child, Preschool; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Infant; Infant, Newborn; Lipoproteins; Male; Middle Aged; Prospective Studies; Risk Factors; Sex Factors; Triglycerides; Young Adult	2018
Association of Journal of diabetes research, 2018, Volume: 2018 Topics: Aged; Alleles; Case-Control Studies; China; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Epoxide Hydrolases; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Haplotypes; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide	2018
Association of FOLH1, DHFR, and MTHFR gene polymorphisms with susceptibility of Neural Tube Defects: A case control study from Eastern India. Birth defects research, 2018, 08-15, Volume: 110, Issue:14 Topics: Adult; Alleles; Antigens, Surface; Case-Control Studies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; India; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neural Tube Defects; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Tetrahydrofolate Dehydrogenase	2018
Association between increased plasma levels of homocysteine and depression observed in individuals with primary lactose malabsorption. PloS one, 2018, Volume: 13, Issue:8 Topics: Adult; Body Mass Index; Depression; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Lactase; Lactose Intolerance; Male; Middle Aged; Risk Factors; Vitamin B 12	2018
Methylenetetrahydrofolate reductase polymorphism (MTHFR C677T) and headache in children: a retrospective study from a tertiary level outpatient service. Italian journal of pediatrics, 2018, Aug-31, Volume: 44, Issue:1 Topics: Adolescent; Age Distribution; Ambulatory Care; Child; Child, Preschool; Cohort Studies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Migraine Disorders; Polymorphism, Genetic; Prognosis; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Distribution; Tertiary Care Centers	2018
A case report of branch retinal artery occlusion in a teenager due to hyperhomocysteinaemia; the interplay of genetic and nutritional defects. BMC ophthalmology, 2018, Sep-14, Volume: 18, Issue:Suppl 1 Topics: Adolescent; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Methylenetetrahydrofolate Reductase (NADPH2); Retinal Artery Occlusion; Vision Disorders; Visual Acuity; Visual Field Tests; Visual Fields; Vitamin B 12; Vitamin B 12 Deficiency	2018
[The interrelationship of indices of hemocysteine and genetic polymorphisms conditioning disorders of folates metabolism in healthy population]. Klinicheskaia laboratornaia diagnostika, 2017, Volume: 62, Issue:2 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Alleles; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors	2017
Genetically elevated circulating homocysteine concentrations increase the risk of diabetic kidney disease in Chinese diabetic patients. Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:4 Topics: Asian People; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Follow-Up Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Prognosis; Risk Factors	2019
The relationship between plasma homocysteine levels and MTHFR gene variation, age, and sex in Northeast China. Nigerian journal of clinical practice, 2019, Volume: 22, Issue:3 Topics: Adult; Age Factors; Aged; Asian People; Cardiovascular Diseases; China; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Sex Factors; Stroke	2019
Interactions between genetic variants involved in the folate metabolic pathway and serum lipid, homocysteine levels on the risk of recurrent spontaneous abortion. Lipids in health and disease, 2019, Jun-15, Volume: 18, Issue:1 Topics: Abortion, Spontaneous; Adult; Alleles; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy	2019
Association of MTHFR C677T, MTHFR A1298C, and MTRR A66G Polymorphisms with Neural Tube Defects in Tunisian Parents. Pathobiology : journal of immunopathology, molecular and cellular biology, 2019, Volume: 86, Issue:4 Topics: Alleles; Fathers; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Homocystinuria; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Muscle Spasticity; Neural Tube Defects; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pregnancy; Psychotic Disorders; Tunisia	2019
Brachial artery aneurysm accompanying a homozygous methylenetetrahydrofolate reductase mutation. Interactive cardiovascular and thoracic surgery, 2013, Volume: 16, Issue:6 Topics: Adult; Aneurysm; Biomarkers; Brachial Artery; DNA Mutational Analysis; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Phenotype; Saphenous Vein; Treatment Outcome; Vascular Grafting	2013
Geographical distribution of MTHFR C677T, A1298C and MTRR A66G gene polymorphisms in China: findings from 15357 adults of Han nationality. PloS one, 2013, Volume: 8, Issue:3 Topics: Adult; Alleles; Asian People; Case-Control Studies; China; Female; Ferredoxin-NADP Reductase; Genetic Predisposition to Disease; Genotype; Geography; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Prevalence; Sequence Analysis, DNA; Sex Factors; Young Adult	2013
Serum homocysteine and methylmalonic acid concentrations in Chinese Shar-Pei dogs with cobalamin deficiency. Veterinary journal (London, England : 1997), 2013, Volume: 197, Issue:2 Topics: Animals; Dog Diseases; Dogs; Genetic Predisposition to Disease; Homocysteine; Methylmalonic Acid; Retrospective Studies; Vitamin B 12 Deficiency	2013
Association of methylenetetrahydrofolate reductase A1298C polymorphism but not of C677T with multiple sclerosis in Tunisian patients. Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:9 Topics: Adolescent; Adult; Data Interpretation, Statistical; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multiple Sclerosis; Mutation, Missense; Polymerase Chain Reaction; Polymorphism, Genetic; Tunisia; Young Adult	2013
Plasmatic higher levels of homocysteine in non-alcoholic fatty liver disease (NAFLD). Nutrition journal, 2013, Apr-02, Volume: 12 Topics: Adult; Biomarkers; Brazil; Cholesterol; Chronic Disease; Fatty Liver; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Leukocytes, Mononuclear; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Non-alcoholic Fatty Liver Disease; Polymorphism, Genetic; Triglycerides; Vitamin B 12	2013
Methylenetetrahydrofolate reductase (C677T and A1298C) polymorphisms, hyperhomocysteinemia, and ischemic stroke in Tunisian patients. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2013, Volume: 22, Issue:4 Topics: Adult; Aged; Biomarkers; Brain Ischemia; Case-Control Studies; Chi-Square Distribution; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Phenotype; Polymorphism, Genetic; Risk Factors; Stroke; Tunisia; Up-Regulation	2013
Plasma total homocysteine is associated with abdominal aortic aneurysm and aortic diameter in older men. Journal of vascular surgery, 2013, Volume: 58, Issue:2 Topics: Age Factors; Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Biomarkers; Comorbidity; Cross-Sectional Studies; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoassay; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Odds Ratio; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Assessment; Risk Factors; Sex Factors; Ultrasonography; Up-Regulation; Western Australia	2013
Association of methylenetetrahydrofolate reductase polymorphisms with susceptibility to Alzheimer's disease. Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:9 Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Mutation, Missense; Polymorphism, Genetic; Risk Factors	2013
Genetic variants reducing MTR gene expression increase the risk of congenital heart disease in Han Chinese populations. European heart journal, 2014, Volume: 35, Issue:11 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Asian People; Case-Control Studies; DNA Methylation; Ferredoxin-NADP Reductase; Gene Expression; Genetic Predisposition to Disease; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; MicroRNAs; Risk Factors; Transcription, Genetic	2014
Genetic association of five plasminogen activator inhibitor-1 (PAI-1) polymorphisms and idiopathic recurrent pregnancy loss in Korean women. Thrombosis and haemostasis, 2013, Volume: 110, Issue:4 Topics: Abortion, Habitual; Adult; Blood Coagulation; DNA Mutational Analysis; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Korea; Middle Aged; Mutation; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Pregnancy; Young Adult	2013
MTHFR C677T and A1298C gene polymorphisms and their relation to homocysteine level in Egyptian children with congenital heart diseases. Gene, 2013, Oct-15, Volume: 529, Issue:1 Topics: Alleles; Case-Control Studies; Child; Child, Preschool; Egypt; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Factors	2013
Gene-environment and gene-gene interactions of specific MTHFR, MTR and CBS gene variants in relation to homocysteine in black South Africans. Gene, 2013, Nov-01, Volume: 530, Issue:1 Topics: Adult; Cystathionine beta-Synthase; Epistasis, Genetic; Female; Gene-Environment Interaction; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Phosphotransferases (Alcohol Group Acceptor); Polymorphism, Single Nucleotide; South Africa	2013
The MTHFR 677T allele may influence the severity and biochemical risk factors of Alzheimer's disease in an Egyptian population. Disease markers, 2013, Volume: 35, Issue:5 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholesterol; Egypt; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12	2013
Association of polymorphisms on chromosome 9p21.3 region with increased susceptibility of abdominal aortic aneurysm in a Chinese Han population. Journal of vascular surgery, 2014, Volume: 59, Issue:4 Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Chromosomes, Human, Pair 9; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Factors	2014
Genetic variants of homocysteine metabolism and multiple sclerosis: a case-control study. Neuroscience letters, 2014, Mar-06, Volume: 562 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Case-Control Studies; Cystathionine beta-Synthase; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multiple Sclerosis; Polymorphism, Genetic; S-Adenosylmethionine	2014
Genetic polymorphisms in the methylenetetrahydrofolate reductase gene (MTHFR) and risk of vitiligo in Han Chinese populations: a genotype-phenotype correlation study. The British journal of dermatology, 2014, Volume: 170, Issue:5 Topics: Adult; Asian People; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Vitiligo	2014
An MTHFR variant, plasma homocysteine levels and late-onset coronary artery disease in subjects from southern Iran. Pakistan journal of biological sciences : PJBS, 2013, Aug-15, Volume: 16, Issue:16 Topics: Age of Onset; Aged; Biomarkers; Chi-Square Distribution; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Phenotype; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors	2013
Variation in the MC4R gene is associated with bone phenotypes in elderly Swedish women. PloS one, 2014, Volume: 9, Issue:2 Topics: Adiposity; Aged; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Biomarkers; Body Composition; Bone and Bones; Cohort Studies; Female; Fractures, Bone; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Obesity; Phenotype; Polymorphism, Single Nucleotide; Proteins; Receptor, Melanocortin, Type 4; Sweden; Ultrasonography	2014
Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in nulliparous women complicated with preeclampsia. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2014, Volume: 30, Issue:5 Topics: Case-Control Studies; Chi-Square Distribution; DNA; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Young Adult	2014
Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene rs4073259 polymorphism not associated with ischemic stroke in the northeastern Chinese Han population. Clinical neurology and neurosurgery, 2014, Volume: 119 Topics: 5-Lipoxygenase-Activating Proteins; Adult; Aged; Asian People; Brain Ischemia; Carotid Artery Diseases; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Plaque, Atherosclerotic; Polymorphism, Single Nucleotide; Severity of Illness Index; Sex Factors; Stroke	2014
Association between common genetic variants of α2A-, α2B- and α2C-adrenoceptors and the risk of silent brain infarction. Molecular medicine reports, 2014, Volume: 9, Issue:6 Topics: Aged; Alleles; Asymptomatic Diseases; Brain Infarction; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptors, Adrenergic, alpha-2; Risk	2014
Association of seven functional polymorphisms of one-carbon metabolic pathway with total plasma homocysteine levels and susceptibility to Parkinson's disease among South Indians. Neuroscience letters, 2014, May-07, Volume: 568 Topics: Case-Control Studies; Female; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; India; Male; Metabolic Networks and Pathways; Parkinson Disease; Polymorphism, Genetic; Sex Factors	2014
Effect of genetic variants associated with plasma homocysteine levels on stroke risk. Stroke, 2014, Volume: 45, Issue:7 Topics: Brain Ischemia; Cohort Studies; Europe; Genetic Association Studies; Genetic Loci; Genetic Predisposition to Disease; Genetic Variation; Genome; Homocysteine; Humans; Polymorphism, Single Nucleotide; Risk; Stroke	2014
Homocysteine, small-vessel disease, and atherosclerosis: an MRI study of 825 stroke patients. Neurology, 2014, Aug-19, Volume: 83, Issue:8 Topics: Atherosclerosis; Brain Ischemia; Cerebral Arteries; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Retrospective Studies; Risk Factors; Stroke	2014
Relationship between methylenetetrahydrofolate reductase gene polymorphism and the coronary slow flow phenomenon. Coronary artery disease, 2014, Volume: 25, Issue:8 Topics: Aged; Biomarkers; Case-Control Studies; Chi-Square Distribution; Coronary Angiography; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; No-Reflow Phenomenon; Phenotype; Polymorphism, Genetic; Risk Factors; Sex Factors	2014
The roles of methylenetetrahydrofolate reductase 677C>T and 1298A>C polymorphisms in moyamoya disease patients. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:10 Topics: Adolescent; Adult; Case-Control Studies; Child; Child, Preschool; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Moyamoya Disease; Nitric Oxide; Polymorphism, Single Nucleotide; Republic of Korea; Vitamin B 12; Young Adult	2014
Distribution and determinants of plasma homocysteine levels in rural Chinese twins across the lifespan. Nutrients, 2014, Dec-18, Volume: 6, Issue:12 Topics: Adolescent; Adult; Age Factors; Aged; Asian People; Cardiovascular Diseases; Child; China; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Homocysteine; Humans; Linear Models; Longevity; Male; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors; Rural Population; Sex Factors; Smoking; Young Adult	2014
Prevalence of hyperhomocysteinaemia and some of its major determinants in Shaanxi Province, China: a cross-sectional study. The British journal of nutrition, 2015, Feb-28, Volume: 113, Issue:4 Topics: Adult; Aged; Aged, 80 and over; China; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutrition Surveys; Polymorphism, Genetic; Prevalence; Risk Factors; Young Adult	2015
Association of folate metabolism gene polymorphisms and pulmonary embolism: A case-control study of West-Siberian population. Thrombosis research, 2015, Volume: 135, Issue:5 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Alleles; Case-Control Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Probability; Pulmonary Embolism; Siberia	2015
Effect of a pre-microRNA-149 (miR-149) genetic variation on the risk of ischemic stroke in a Chinese Han population. Genetics and molecular research : GMR, 2015, Mar-30, Volume: 14, Issue:1 Topics: Aged; Asian People; Brain Ischemia; China; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; MicroRNAs; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Risk; Stroke	2015
Homocysteine levels in normotensive children of hypertensive parents. Anatolian journal of cardiology, 2015, Volume: 15, Issue:12 Topics: Adolescent; Adult; Biomarkers; Child; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hypertension; Male; Parents; Young Adult	2015
Aldehyde dehydrogenase 2 polymorphism as a protective factor for intracranial vascular stenosis in ischemic stroke in Han Chinese. The International journal of neuroscience, 2016, Volume: 126, Issue:4 Topics: Alcohol Drinking; Aldehyde Dehydrogenase; Alleles; Asian People; Case-Control Studies; Constriction, Pathologic; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Intracranial Arterial Diseases; Magnetic Resonance Angiography; Male; Middle Aged; Mutation; Polymorphism, Genetic; Protective Factors; Risk Factors; Stroke	2016
MTHFR 677C/T and 1298A/C mutations and non-alcoholic fatty liver disease. Clinical medicine (London, England), 2015, Volume: 15, Issue:3 Topics: Adult; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Non-alcoholic Fatty Liver Disease; Vitamin B 12	2015
Role of folate-homocysteine pathway gene polymorphisms and nutritional cofactors in Down syndrome: A triad study. Human reproduction (Oxford, England), 2015, Volume: 30, Issue:8 Topics: Adult; Alleles; Diet; Down Syndrome; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors	2015
Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans. Scientific reports, 2015, Jun-05, Volume: 5 Topics: 3' Untranslated Regions; Adenocarcinoma; Aged; Colorectal Neoplasms; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Republic of Korea	2015
Gene polymorphisms as risk factors for predicting the cardiovascular manifestations in Marfan syndrome. Role of folic acid metabolism enzyme gene polymorphisms in Marfan syndrome. Thrombosis and haemostasis, 2015, Volume: 114, Issue:4 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Aortic Aneurysm; Aortic Dissection; Biomarkers; Case-Control Studies; Chi-Square Distribution; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homozygote; Humans; Logistic Models; Male; Marfan Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Predictive Value of Tests; Risk Factors; Severity of Illness Index; Up-Regulation; Vitamin B 12; Young Adult	2015
3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population. PloS one, 2015, Volume: 10, Issue:7 Topics: 3' Untranslated Regions; Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; DEAD-box RNA Helicases; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Karyopherins; Male; MicroRNAs; Middle Aged; Polymorphism, Single Nucleotide; ran GTP-Binding Protein; Republic of Korea; Ribonuclease III; Risk; RNA, Neoplasm; Tumor Burden	2015
Clinical characteristics of hemolytic uremic syndrome secondary to cobalamin C disorder in Chinese children. World journal of pediatrics : WJP, 2015, Volume: 11, Issue:3 Topics: Carrier Proteins; Child, Preschool; China; Female; Follow-Up Studies; Genetic Predisposition to Disease; Hemolytic-Uremic Syndrome; Homocysteine; Humans; Infant; Male; Mutation; Oxidoreductases; Rare Diseases; Retrospective Studies; Risk Assessment; Sampling Studies; Severity of Illness Index; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency	2015
Joint associations of folate, homocysteine and MTHFR, MTR and MTRR gene polymorphisms with dyslipidemia in a Chinese hypertensive population: a cross-sectional study. Lipids in health and disease, 2015, Sep-04, Volume: 14 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; China; Cross-Sectional Studies; Dyslipidemias; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Expression; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Triglycerides	2015
Fetal Val108/158Met catechol-O-methyltransferase (COMT) polymorphism and placental COMT activity are associated with the development of preeclampsia. Fertility and sterility, 2016, Volume: 105, Issue:1 Topics: 2-Methoxyestradiol; Adult; Biomarkers; Blood Pressure; Case-Control Studies; Catechol O-Methyltransferase; Chi-Square Distribution; Estradiol; Female; Fetal Blood; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Hospitals, University; Humans; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Odds Ratio; Phenotype; Placenta; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Prospective Studies; Risk Assessment; Risk Factors; Spain	2016
[One-carbon Metabolism and Schizophrenia]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2015, Volume: 117, Issue:5 Topics: Adult; Carbon; DNA Methylation; Female; Genetic Predisposition to Disease; Genome, Human; Homocysteine; Humans; Male; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors; Schizophrenia	2015
Associations of Polymorphisms in MTHFR Gene with the Risk of Age-Related Cataract in Chinese Han Population: A Genotype-Phenotype Analysis. PloS one, 2015, Volume: 10, Issue:12 Topics: Aged; Aged, 80 and over; Aging; Asian People; Case-Control Studies; Cataract; Female; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6	2015
High homocysteine and epistasis between MTHFR and APOE: association with cognitive performance in the elderly. Experimental gerontology, 2016, Volume: 76 Topics: Age Factors; Aged; Aging; Apolipoproteins E; Biomarkers; Cognition; Cognition Disorders; Cross-Sectional Studies; Epistasis, Genetic; Executive Function; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Phenotype; Polymorphism, Genetic; Principal Component Analysis; Risk Factors; Up-Regulation	2016
The association of single nucleotide polymorphisms of the maternal cystathionine-β-synthase gene with early-onset preeclampsia. Pregnancy hypertension, 2016, Volume: 6, Issue:1 Topics: Adult; Biomarkers; Blood Pressure; Case-Control Studies; Cystathionine; Cystathionine beta-Synthase; Cysteine; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Gestational Age; Homocysteine; Humans; Phenotype; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Protective Factors; Risk Factors	2016
Correlation between the 677C>T polymorphism in the methylene tetrahydrofolate reductase gene and serum homocysteine levels in coronary heart disease. Genetics and molecular research : GMR, 2016, Mar-28, Volume: 15, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Coronary Artery Disease; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic	2016
Methylenetetrahydrofolate reductase C677T polymorphism, hypertension and risk of stroke: a prospective, nested case-control study. The International journal of neuroscience, 2017, Volume: 127, Issue:3 Topics: Adult; Aged; Case-Control Studies; China; Fasting; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hypertension; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Prospective Studies; Risk Factors; Stroke	2017
Haplotypes of the MTHFR gene are associated with an increased risk of breast cancer in a Han Chinese population in Gansu province. IUBMB life, 2016, Volume: 68, Issue:7 Topics: Adult; Asian People; Breast Neoplasms; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Haplotypes; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors	2016
Homocysteine concentration in coronary artery disease: Influence of three common single nucleotide polymorphisms. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2017, Volume: 27, Issue:2 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Area Under Curve; Biomarkers; Case-Control Studies; Chi-Square Distribution; Coronary Artery Disease; Cystathionine beta-Synthase; Disease Progression; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homozygote; Humans; Kaplan-Meier Estimate; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Phenotype; Polymorphism, Single Nucleotide; Predictive Value of Tests; Proportional Hazards Models; Risk Assessment; Risk Factors; ROC Curve; Stroke; Time Factors	2017
Cumulative effect of the plasma total homocysteine-related genetic variants on schizophrenia risk. Psychiatry research, 2016, Dec-30, Volume: 246 Topics: Adult; Biomarkers; Female; Genetic Predisposition to Disease; Genetic Variation; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Schizophrenia; Schizophrenic Psychology	2016
Is hyperhomocysteinemia a causal factor for heart failure? The impact of the functional variants of MTHFR and PON1 on ischemic and non-ischemic etiology. International journal of cardiology, 2017, Feb-01, Volume: 228 Topics: Aged; Aryldialkylphosphatase; Cardiomyopathy, Dilated; Causality; Female; Genetic Predisposition to Disease; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Ischemia; Poland; Risk Factors; Stroke Volume	2017
Influence of MTHFR C677T gene polymorphism in the development of cardiovascular disease in Egyptian patients with rheumatoid arthritis. Gene, 2017, Apr-30, Volume: 610 Topics: Adult; Arthritis, Rheumatoid; Atherosclerosis; Carotid Intima-Media Thickness; Egypt; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Regression Analysis	2017
Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes. Genetics and molecular research : GMR, 2017, Feb-23, Volume: 16, Issue:1 Topics: Adolescent; Adult; Brazil; Cross-Sectional Studies; Cystathionine beta-Synthase; Epistasis, Genetic; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Linkage Disequilibrium; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Thrombophilia; Thrombosis; Vitamin B 12; Young Adult	2017
His595Tyr polymorphism in the methionine synthase reductase (MTRR) gene is associated with pancreatic cancer risk. Gastroenterology, 2008, Volume: 135, Issue:2 Topics: Adult; Aged; Carcinoma, Pancreatic Ductal; Case-Control Studies; Cell Line; Culture Media; DNA Methylation; Female; Ferredoxin-NADP Reductase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Japan; Long Interspersed Nucleotide Elements; Male; Middle Aged; Mutation, Missense; Odds Ratio; Pancreatic Neoplasms; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Transfection	2008
High plasma homocysteine is associated with the risk of coronary artery disease independent of methylenetetrahydrofolate reductase 677C-->T genotypes. Asia Pacific journal of clinical nutrition, 2008, Volume: 17, Issue:2 Topics: Alleles; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2008
Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysm. Journal of medical genetics, 2008, Volume: 45, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; DNA Methylation; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Linkage Disequilibrium; Male; Methionine; Middle Aged; Polymorphism, Single Nucleotide; Proteins	2008
Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population. European journal of neurology, 2008, Volume: 15, Issue:12 Topics: Acute Disease; Asian People; Brain Ischemia; DNA Mutational Analysis; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitric Oxide Synthase Type III; Nitrites; Polymorphism, Genetic; Singapore; Stroke	2008
Plasma homocysteine levels, the prevalence of methylenetetrahydrofolate reductase gene C677T polymorphism and macrovascular disorders in systemic sclerosis: risk factors for accelerated macrovascular damage? Clinical reviews in allergy & immunology, 2009, Volume: 36, Issue:2-3 Topics: Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hypertrophy, Right Ventricular; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Pulmonary Fibrosis; Risk Factors; Scleroderma, Systemic; Thromboembolism; Time Factors	2009
Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss. Clinical biochemistry, 2009, Volume: 42, Issue:4-5 Topics: Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; DNA Damage; Embryo Loss; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Micronuclei, Chromosome-Defective; Parents; Polymorphism, Single Nucleotide; Pregnancy; Recurrence; Young Adult	2009
Lack of association of polymorphisms in homocysteine metabolism genes with pseudoexfoliation syndrome and glaucoma. Molecular vision, 2008, Volume: 14 Topics: Aged; Amino Acid Oxidoreductases; Exfoliation Syndrome; Female; Genetic Predisposition to Disease; Glaucoma; Homocysteine; Humans; Male; Polymorphism, Single Nucleotide	2008
Association between genetic and environmental factors and the risk of Alzheimer's disease. Folia neuropathologica, 2008, Volume: 46, Issue:4 Topics: Alzheimer Disease; Apolipoproteins E; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hypercholesterolemia; Methylenetetrahydrofolate Reductase (NADPH2); Nitric Oxide Synthase Type III; Risk Factors; Vitamin B 12	2008
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice. Gut, 2009, Volume: 58, Issue:6 Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Colorectal Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Pregnancy; Prenatal Nutritional Physiological Phenomena; Random Allocation; Thymine Nucleotides; Uridine Triphosphate; Weaning	2009
Brain MRI, apoliprotein E genotype, and plasma homocysteine in American Indian Alzheimer disease patients and Indian controls. Current Alzheimer research, 2009, Volume: 6, Issue:1 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Brain; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Indians, North American; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Polymorphism, Genetic	2009
One carbon metabolism disturbances and the C677T MTHFR gene polymorphism in children with autism spectrum disorders. Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:10 Topics: Aminobutyrates; Carbon; Case-Control Studies; Child; Child Development Disorders, Pervasive; Female; Genetic Predisposition to Disease; Genotype; Glutathione; Homocysteine; Humans; Male; Metabolic Networks and Pathways; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide	2009
Methionine synthase reductase (MTRR) A66G polymorphism is not related to plasma homocysteine concentration and the risk for vascular disease. Experimental and molecular pathology, 2009, Volume: 86, Issue:2 Topics: Adult; Aged; Case-Control Studies; Female; Ferredoxin-NADP Reductase; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Vascular Diseases	2009
Differential thiol status in blood of different mouse strains exposed to cigarette smoke. Free radical research, 2009, Volume: 43, Issue:6 Topics: Animals; Cysteine; Dipeptides; Emphysema; Genetic Predisposition to Disease; Glutathione; Glutathione Disulfide; Homocysteine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Oxidative Stress; Sulfhydryl Compounds; Tobacco Smoke Pollution	2009
Family history of premature cardiovascular disease as a sole and independent risk factor for increased carotid intima-media thickness. Journal of hypertension, 2009, Volume: 27, Issue:4 Topics: Cardiovascular Diseases; Carotid Arteries; Child; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Insulin Resistance; Linear Models; Lipids; Male; Oxidative Stress; Risk Factors; Sample Size; Tunica Intima; Tunica Media	2009
Role of thrombotic risk factors in end-stage renal disease. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2010, Volume: 16, Issue:2 Topics: 3' Untranslated Regions; Adult; Alleles; Amino Acid Substitution; Factor V; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Point Mutation; Prothrombin; Risk Factors; Thrombophilia; Vitamin B 12; Young Adult	2010
Relationship between genetic polymorphism, serum folate and homocysteine in Alzheimer's disease. Asia-Pacific journal of public health, 2008, Volume: 20 Suppl Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide	2008
Association of plasma homocysteine and methylenetetrahydrofolate reductase C677T gene variant with schizophrenia: A Chinese Han population-based case-control study. Psychiatry research, 2009, Aug-15, Volume: 168, Issue:3 Topics: Adult; Case-Control Studies; China; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Restriction Fragment Length; Risk Factors; Schizophrenia	2009
The relationship between homocysteine and genes of folate-related enzymes in migraine patients. Headache, 2010, Volume: 50, Issue:1 Topics: Adult; Algorithms; DNA Mutational Analysis; Epigenesis, Genetic; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Migraine Disorders; Migraine with Aura; Polymorphism, Genetic; Sex Characteristics; Sex Factors; Thymidylate Synthase	2010
The reduced folate carrier (SLC19A1) c.80G>A polymorphism is associated with red cell folate concentrations among women. Annals of human genetics, 2009, Volume: 73, Issue:Pt 5 Topics: Adolescent; Adult; Child; Erythrocytes; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Membrane Transport Proteins; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Sex Characteristics; Young Adult	2009
Changes in lifestyle, biological risk factors and total homocysteine in relation to MTHFR C677T genotype: a 5-year follow-up study. European journal of clinical nutrition, 2009, Volume: 63, Issue:10 Topics: Adult; Alcohol Drinking; Beer; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cholesterol; Coffee; Cross-Sectional Studies; Denmark; Feeding Behavior; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors; Smoking; Tea; Waist Circumference	2009
Sacroiliitis and muscle cramps in a healthy young man: some spearhead on MTHFR mutations. Rheumatology international, 2010, Volume: 30, Issue:7 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Biomarkers; DNA Mutational Analysis; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Keratolytic Agents; Low Back Pain; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Cramp; Muscle, Skeletal; Mutation; Radiography; Sacroiliac Joint; Sulfasalazine; Tretinoin	2010
Methylenetetrahydrofolate reductase polymorphisms and plasma homocysteine in levodopa-treated and non-treated Parkinson's disease patients. Journal of the neurological sciences, 2009, Dec-15, Volume: 287, Issue:1-2 Topics: Age Distribution; Aged; Aged, 80 and over; Amino Acid Substitution; Antiparkinson Agents; Base Sequence; Biomarkers; DNA Mutational Analysis; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Levodopa; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Parkinson Disease; Polymorphism, Genetic; Sex Distribution	2009
Epidemiology of intracranial stenosis. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2009, Volume: 19 Suppl 1 Topics: Age Factors; Asian People; Black or African American; Constriction, Pathologic; Endostatins; Female; Genetic Predisposition to Disease; Glutathione Transferase; Hispanic or Latino; Homocysteine; Humans; Intracranial Arterial Diseases; Intracranial Arteriosclerosis; Male; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Prevalence; Risk Factors; Sex Factors; Vascular Endothelial Growth Factor A; White People	2009
Hyperhomocysteinaemia, low folate concentrations and methylene tetrahydrofolate reductase C677T mutation in acute mesenteric venous thrombosis. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2010, Volume: 39, Issue:4 Topics: Acute Disease; Adult; Aged; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Chromatography, High Pressure Liquid; Down-Regulation; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoassay; Male; Mesenteric Vascular Occlusion; Mesenteric Veins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Risk Assessment; Risk Factors; Venous Thrombosis; Vitamin B 12; Young Adult	2010
One-carbon metabolism and schizophrenia: current challenges and future directions. Trends in molecular medicine, 2009, Volume: 15, Issue:12 Topics: Carbon; DNA Methylation; Environment; Epigenesis, Genetic; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Humans; Metabolic Networks and Pathways; Methionine; Mitochondrial Diseases; Receptors, Glutamate; Schizophrenia; Time Factors	2009
The maternal homocysteine pathway is influenced by riboflavin intake and MTHFR polymorphisms without affecting the risk of orofacial clefts in the offspring. European journal of clinical nutrition, 2010, Volume: 64, Issue:3 Topics: Biomarkers; Case-Control Studies; Cleft Lip; Cleft Palate; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Linear Models; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Nutrigenomics; Odds Ratio; Polymorphism, Genetic; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B 12	2010
One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent study. Cancer causes & control : CCC, 2010, Volume: 21, Issue:4 Topics: Aged; Carbon; Case-Control Studies; Colorectal Neoplasms; CpG Islands; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Sweden; Vitamin B 12	2010
Hyperhomocysteinemia recurrence in levodopa-treated Parkinson's disease patients. European journal of neurology, 2010, Volume: 17, Issue:5 Topics: Aged; Cross-Sectional Studies; Dopamine Agents; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Prospective Studies; Secondary Prevention; Treatment Outcome; Vitamin B 12	2010
Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults. Human molecular genetics, 2010, May-15, Volume: 19, Issue:10 Topics: Carbamoyl-Phosphate Synthase (Ammonia); Cardiovascular Diseases; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genome-Wide Association Study; Health Surveys; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Nutrition Surveys; Philippines; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Reproducibility of Results; Young Adult	2010
[Features of allele polymorphism of genes involved in homocysteine and folate metabolism in patients with atherosclerosis of the lower extremity arteries]. Vestnik khirurgii imeni I. I. Grekova, 2009, Volume: 168, Issue:6 Topics: Alleles; Atherosclerosis; DNA; Female; Ferredoxin-NADP Reductase; Flavoproteins; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Leg; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Prognosis; Severity of Illness Index	2009
Nutrigenetic impact of daily folate intake on plasma homocysteine and folate levels in patients with different methylenetetrahydrofolate reductase genotypes. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2010, Volume: 17, Issue:6 Topics: Biomarkers; Chi-Square Distribution; Dietary Supplements; Drug Administration Schedule; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Israel; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Nutrigenomics; Odds Ratio; Phenotype	2010
Does the progeny of premature ischemic stroke sufferers need intensive interest of physicians oriented toward primary prevention? A pilot study. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2010, Volume: 17, Issue:6 Topics: Adult; Age of Onset; Analysis of Variance; Biomarkers; Brain Ischemia; Case-Control Studies; Female; Fibrinogen; Genetic Predisposition to Disease; Heredity; Homocysteine; Humans; Lipids; Logistic Models; Male; Odds Ratio; Pedigree; Phenotype; Pilot Projects; Poland; Primary Prevention; Risk Assessment; Risk Factors; Stroke; Young Adult	2010
Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism. Thrombosis and haemostasis, 2010, Volume: 104, Issue:2 Topics: Adolescent; Adult; Age of Onset; Aged; Brain Ischemia; Case-Control Studies; Chi-Square Distribution; Child; Female; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Italy; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Stroke; Young Adult	2010
Methylenetetrahydrofolate reductase C677T gene mutation as risk factor for sudden sensorineural hearing loss: association with plasma homocysteine, folate and cholesterol concentrations. The Journal of laryngology and otology, 2010, Volume: 124, Issue:12 Topics: Adolescent; Adult; Aged; Case-Control Studies; Child; Cholesterol; Cochlea; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Risk Factors; Young Adult	2010
Differential contribution of MTHFR C677T variant to the risk of diabetic nephropathy in Lebanese and Bahraini Arabs. Clinical chemistry and laboratory medicine, 2010, Volume: 48, Issue:8 Topics: Adult; Alleles; Amino Acid Substitution; Arabs; Bahrain; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Lebanon; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide	2010
C677T polymorphism of the methylenetetrahydrofolate reductase gene does not affect folic acid, vitamin B12, and homocysteine serum levels in Turkish children with neural tube defects. Genetics and molecular research : GMR, 2010, Jun-22, Volume: 9, Issue:2 Topics: Adult; Alleles; Child; Child, Preschool; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Genetic; Turkey; Vitamin B 12	2010
Genetic polymorphism of methylenetetrahydrofolate reductase G1793A, hyperhomocysteinemia, and folate deficiency correlate with ulcerative colitis in central China. Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:6 Topics: Adult; Alleles; China; Colitis, Ulcerative; DNA; Female; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Prevalence; Vitamin B 12	2010
Could genetic analysis be useful in reducing cerebrovascular risk in hypertensive subjects with hyperhomocysteinemia and patent foramen ovale? A 2-year follow-up study. Microvascular research, 2010, Volume: 80, Issue:3 Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Blood Pressure; Cerebrovascular Disorders; Chi-Square Distribution; Echocardiography, Transesophageal; Female; Folic Acid; Follow-Up Studies; Foramen Ovale, Patent; Gene Frequency; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Hypertension; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymorphism, Genetic; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial; Vitamins; Young Adult	2010
Association between tumor necrosis factor-alpha (-308G→A and -238G→A) polymorphisms and homocysteine levels in patients with ischemic strokes and silent brain infarctions. Cerebrovascular diseases (Basel, Switzerland), 2010, Volume: 30, Issue:5 Topics: Aged; Alleles; Brain Infarction; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Korea; Male; Middle Aged; Polymorphism, Single Nucleotide; Sex Characteristics; Stroke; Tumor Necrosis Factor-alpha	2010
The relationship of cardiovascular risk factors to Alzheimer disease in Choctaw Indians. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2011, Volume: 19, Issue:5 Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Cardiovascular Diseases; Case-Control Studies; Diabetes Mellitus; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hypertension; Indians, North American; Male; Middle Aged; Oklahoma; Risk Factors; Statistics, Nonparametric; White People	2011
Plasma total homocysteine and the methylenetetrahydrofolate reductase 677C>T polymorphism do not contribute to the distribution of cervico-cerebral atherosclerosis in ischaemic stroke patients. European journal of neurology, 2011, Volume: 18, Issue:3 Topics: Aged; Atherosclerosis; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Immunoassay; Magnetic Resonance Angiography; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Stroke	2011
Methylenetetrahydrofolate reductase C677T polymorphism in patients with Henoch-Schönlein purpura. Pediatrics international : official journal of the Japan Pediatric Society, 2011, Volume: 53, Issue:3 Topics: Adolescent; Child; Child, Preschool; Chromatography, High Pressure Liquid; DNA; Electrophoresis, Agar Gel; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; IgA Vasculitis; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic	2011
Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:11 Topics: Aged; Biomarkers, Tumor; Disease Progression; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Prostate-Specific Antigen; Prostatic Neoplasms; Signal Transduction; Vitamin B 12	2010
Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase. Phlebology, 2011, Volume: 26, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Factor V; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Mutation, Missense; Prothrombin; Thrombophlebitis; Varicose Veins; Venous Thrombosis	2011
Polymorphisms in MTHFR and MTRR genes associated with blood plasma homocysteine concentration and sperm counts. Fertility and sterility, 2011, Volume: 95, Issue:2 Topics: Adult; Cohort Studies; Female; Ferredoxin-NADP Reductase; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Osmolar Concentration; Polymorphism, Single Nucleotide; Semen Analysis; Sperm Count	2011
Clinical, biochemical, and molecular analysis of combined methylmalonic acidemia and hyperhomocysteinemia (cblC type) in China. Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3 Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Carnitine; Carrier Proteins; Child, Preschool; China; Codon, Nonsense; DNA Mutational Analysis; Exons; Gas Chromatography-Mass Spectrometry; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Oxidoreductases; Phenotype; Vitamin B 12 Deficiency	2010
Mutations in methylenetetrahydrofolate reductase and in cysthationine beta synthase: is there a link to homocysteine levels in peripheral arterial disease? Molecular biology reports, 2011, Volume: 38, Issue:5 Topics: Aged; Brazil; Cystathionine beta-Synthase; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Peripheral Arterial Disease; Risk Factors	2011
Association of haptoglobin genotype and common cardiovascular risk factors with the amount of iron in atherosclerotic carotid plaques. Atherosclerosis, 2011, Volume: 216, Issue:1 Topics: Aged; Cardiovascular Diseases; Carotid Stenosis; Diabetes Mellitus; Endarterectomy, Carotid; Female; Genetic Predisposition to Disease; Greece; Haptoglobins; Hemosiderin; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Iron; Linear Models; Male; Middle Aged; Oxidative Stress; Phenotype; Plaque, Atherosclerotic; Risk Assessment; Risk Factors; Severity of Illness Index; Sex Factors; Staining and Labeling	2011
Genetic variability in the methylenetetrahydrofolate reductase gene (MTHFR) affects clinical expression of Wilson's disease. Journal of hepatology, 2011, Volume: 55, Issue:4 Topics: Adenosine Triphosphatases; Adolescent; Adult; Age of Onset; Cation Transport Proteins; Child; Copper; Copper-Transporting ATPases; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Hepatolenticular Degeneration; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Phenotype; Young Adult	2011
Interactions between genetic variants of folate metabolism genes and lifestyle affect plasma homocysteine concentrations in the Boston Puerto Rican population. Public health nutrition, 2011, Volume: 14, Issue:10 Topics: Aged; Alcohol Drinking; Alleles; Boston; Cross-Sectional Studies; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Life Style; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Motor Activity; Polymorphism, Single Nucleotide; Proton-Coupled Folate Transporter; Puerto Rico; Sex Factors; Smoking; Vitamin B 12	2011
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and cognitive impairment: the health in men study. Molecular psychiatry, 2012, Volume: 17, Issue:5 Topics: Aged, 80 and over; Aging; Case-Control Studies; Cognition Disorders; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Men's Health; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide	2012
Gain-of-function polymorphisms of cystathionine β-synthase and delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage. Journal of neurosurgery, 2011, Volume: 115, Issue:1 Topics: Aged; Brain Ischemia; Cystathionine beta-Synthase; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrogen Sulfide; Male; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Subarachnoid Hemorrhage; Time Factors; Vasospasm, Intracranial	2011
Plasma homocysteine levels, methylene tetrahydrofolate reductase polymorphisms, and the risk of thromboembolism in children. Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:5 Topics: Adolescent; Child; Child, Preschool; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Prevalence; Reference Values; Risk Factors; Thromboembolism; Vitamin B Complex; Young Adult	2011
The basis of differential responses to folic acid supplementation. Journal of nutrigenetics and nutrigenomics, 2011, Volume: 4, Issue:2 Topics: Aged; Aged, 80 and over; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Genetic; Nutrigenomics; Polymorphism, Single Nucleotide; Twins, Dizygotic; Twins, Monozygotic; Vitamin B 12	2011
Prospective study of first stroke in relation to plasma homocysteine and MTHFR 677C>T and 1298A>C genotypes and haplotypes - evidence for an association with hemorrhagic stroke. Clinical chemistry and laboratory medicine, 2011, Volume: 49, Issue:9 Topics: Adult; Aged; Disease-Free Survival; Female; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Hemorrhage; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Prospective Studies; Stroke	2011
Polymorphism C1420T of Serine hydroxymethyltransferase gene on maternal risk for Down syndrome. Molecular biology reports, 2012, Volume: 39, Issue:3 Topics: DNA Primers; Down Syndrome; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Inheritance Patterns; Logistic Models; Methylmalonic Acid; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors	2012
Association between VEGF polymorphisms and homocysteine levels in patients with ischemic stroke and silent brain infarction. Stroke, 2011, Volume: 42, Issue:9 Topics: Aged; Alleles; Asian People; Brain Infarction; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Korea; Male; Middle Aged; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors; Stroke; Vascular Endothelial Growth Factor A	2011
Plasma homocysteine and MTHFRC677T polymorphism as risk factors for incident dementia. Journal of neurology, neurosurgery, and psychiatry, 2012, Volume: 83, Issue:1 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Aged, 80 and over; Dementia; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Longitudinal Studies; Male; Polymorphism, Single Nucleotide; Risk Factors	2012
Evaluation of the MTHFR A1298C variant in leukoaraiosis. Journal of molecular neuroscience : MN, 2012, Volume: 46, Issue:3 Topics: Adult; Aged; Female; Genetic Carrier Screening; Genetic Predisposition to Disease; Genetic Variation; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multigene Family; Point Mutation; Risk Factors	2012
A comprehensive association analysis of homocysteine metabolic pathway genes in Singaporean Chinese with ischemic stroke. PloS one, 2011, Volume: 6, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Asian People; Female; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Singapore; Stroke	2011
Folate and vitamin B12-related genes and risk for omphalocele. Human genetics, 2012, Volume: 131, Issue:5 Topics: Folic Acid; Genetic Predisposition to Disease; Genotype; Hernia, Umbilical; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Pilot Projects; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Risk; Vitamin B 12	2012
A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis. PloS one, 2011, Volume: 6, Issue:11 Topics: Alleles; Case-Control Studies; Folic Acid; Gene Expression Profiling; Genetic Predisposition to Disease; Hispanic or Latino; Homocysteine; Humans; Infant, Newborn; Metabolic Networks and Pathways; Models, Genetic; Mutation; Purines; Risk Factors; Spinal Dysraphism; White People	2011
Familial genetic risk factors in premature cardiovascular disease: a family study. Molecular biology reports, 2012, Volume: 39, Issue:5 Topics: Adult; Cardiovascular Diseases; Demography; Family; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Genetic; Risk Factors	2012
Solute Carrier Family 19, member 1 (SLC19A1) polymorphisms (-43T>C, 80G>A, and 696C>T), and haplotypes in idiopathic recurrent spontaneous abortion in a Korean population. Reproductive sciences (Thousand Oaks, Calif.), 2012, Volume: 19, Issue:5 Topics: Abortion, Habitual; Adult; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; Homocysteine; Humans; Korea; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pregnancy; Reduced Folate Carrier Protein; Risk Factors	2012
[Neonatal renal vein thrombosis in a heterozygous carrier of both factor V Leiden and the MTHFR gene mutation]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2012, Volume: 19, Issue:4 Topics: Diagnosis, Differential; DNA Mutational Analysis; Factor V; Genetic Carrier Screening; Genetic Predisposition to Disease; Genetic Testing; Homocysteine; Homozygote; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Renal Veins; Thrombophilia; Venous Thrombosis	2012
Higher incidence of C677T polymorphism of the MTHFR gene in North Indian patients with vascular disease. Vascular, 2012, Volume: 20, Issue:2 Topics: Adolescent; Adult; Aged; Biomarkers; Case-Control Studies; Chi-Square Distribution; Female; Gene Frequency; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoassay; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Assessment; Risk Factors; Urban Population; Vascular Diseases; Young Adult	2012
Evaluation of possible subclinical atherosclerosis in adolescents with a family history of premature atherosclerosis. Atherosclerosis, 2012, Volume: 222, Issue:2 Topics: Adolescent; Adult; Age of Onset; Aorta; Asymptomatic Diseases; Biomarkers; C-Reactive Protein; Carotid Arteries; Carotid Intima-Media Thickness; Case-Control Studies; Coronary Artery Disease; Echocardiography, Doppler, Pulsed; Elasticity; Fathers; Female; Genetic Predisposition to Disease; Heredity; Homocysteine; Humans; Male; Pedigree; Phenotype; Pulsatile Flow; Risk Assessment; Risk Factors; Turkey	2012
Serum folate, total homocysteine levels and methylenetetrahydrofolate reductase 677C>T polymorphism in young healthy female Japanese. Asia Pacific journal of clinical nutrition, 2012, Volume: 21, Issue:2 Topics: Adolescent; Amplified Fragment Length Polymorphism Analysis; Child; Diet; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Health Surveys; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Vascular Diseases; Vitamin B 12; Vitamin B 6	2012
A case-control nutrigenomic study on the synergistic activity of folate and vitamin B12 in cervical cancer progression. Nutrition and cancer, 2012, Volume: 64, Issue:4 Topics: Case-Control Studies; Drug Synergism; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; India; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Nutrigenomics; Odds Ratio; Polymorphism, Genetic; Risk Assessment; Uterine Cervical Neoplasms; Vitamin B 12; Vitamin B Complex	2012
Folate network genetic variation predicts cardiovascular disease risk in non-Hispanic white males. The Journal of nutrition, 2012, Volume: 142, Issue:7 Topics: Adult; Carbon; Cardiovascular Diseases; Folic Acid; gamma-Glutamyl Hydrolase; Genetic Association Studies; Genetic Predisposition to Disease; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Regression Analysis; Risk Factors; Thymidylate Synthase; White People	2012
Association of COMT, MTHFR, and SLC19A1(RFC-1) polymorphisms with homocysteine blood levels and cognitive impairment in Parkinson's disease. Pharmacogenetics and genomics, 2012, Volume: 22, Issue:10 Topics: Catechol O-Methyltransferase; Cognition Disorders; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Parkinson Disease; Polymorphism, Genetic; Reduced Folate Carrier Protein; Vitamin B 12	2012
C677T methylenetetrahydrofolate reductase gene polymorphism as a risk factor involved in venous thromboembolism: a population-based case-control study. Molecular medicine reports, 2012, Volume: 6, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Alleles; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Venous Thromboembolism	2012
Association of the miR-146a, miR-149, miR-196a2, and miR-499 polymorphisms with ischemic stroke and silent brain infarction risk. Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:2 Topics: Aged; Biomarkers; Brain Infarction; Brain Ischemia; Case-Control Studies; Chi-Square Distribution; Epistasis, Genetic; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Logistic Models; Magnetic Resonance Imaging; Male; MicroRNAs; Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Prevalence; Republic of Korea; Risk Assessment; Risk Factors	2013
Paraoxonase 1 L55M, Q192R and paraoxonase 2 S311C alleles in atherothrombosis. Molecular and cellular biochemistry, 2013, Volume: 374, Issue:1-2 Topics: Alleles; Aryldialkylphosphatase; Cysteine; Female; Genetic Predisposition to Disease; Genotype; Glutathione; Homocysteine; Humans; Hypertension; Ischemic Attack, Transient; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Middle Aged; Myocardial Infarction; Oxidative Stress; Polymorphism, Single Nucleotide; Risk Factors; Stroke; Thrombosis	2013
A possible genetic link between MTHFR genotype and smoking behavior. PloS one, 2012, Volume: 7, Issue:12 Topics: Adult; Behavior, Addictive; Cardiovascular Diseases; Female; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Smoking	2012
Lower incidence of nonsyndromic cleft lip with or without cleft palate in females: is homocysteine a factor? Journal of biosciences, 2013, Volume: 38, Issue:1 Topics: Adolescent; Adult; Alleles; Case-Control Studies; Child; Child, Preschool; Cleft Lip; Cleft Palate; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Incidence; India; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Reduced Folate Carrier Protein; Risk Factors; Sex Factors	2013
Mutations C677T and A1298C of the 5,10-methylenetetrahydrofolate reductase gene and fasting plasma homocysteine levels are not associated with the increased risk of venous thromboembolic disease. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2002, Volume: 13, Issue:5 Topics: 3' Untranslated Regions; Activated Protein C Resistance; Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Codon; Factor V; Fasting; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Poland; Prothrombin; Risk Factors; Thrombophilia; Venous Thrombosis	2002
Analysis of two mutations in the MTHFR gene associated with mild hyperhomocysteinaemia--heterogeneous distribution in the South African population. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2002, Volume: 92, Issue:6 Topics: Cardiovascular Diseases; Genetic Predisposition to Disease; Genetics, Population; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; South Africa	2002
Serum homocysteine, creatinine, and glucose as predictors of the severity and extent of coronary artery disease in asymptomatic members of high-risk families. European journal of clinical investigation, 2002, Volume: 32, Issue:7 Topics: Biomarkers; Blood Glucose; Coronary Angiography; Coronary Disease; Creatinine; Diabetes Complications; Diabetes Mellitus; Diagnosis, Computer-Assisted; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Predictive Value of Tests; Risk Factors	2002
Does prenatal screening for 5,10-methylenetetrahydrofolate reductase (MTHFR) mutations in high-risk neural tube defect pregnancies make sense? Genetic testing, 2002,Spring, Volume: 6, Issue:1 Topics: Animals; Female; Fetal Diseases; Folic Acid; Genetic Predisposition to Disease; Genetic Testing; Homocysteine; Humans; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pregnancy; Prenatal Diagnosis	2002
Hyperhomocysteinemia and venous thromboembolism: a risk factor more prevalent in the elderly and in idiopathic cases. Thrombosis research, 2002, Apr-15, Volume: 106, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Belgium; Case-Control Studies; Fasting; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Prospective Studies; Protein C Deficiency; Pulmonary Embolism; Risk Factors; Thrombophilia; Venous Thrombosis	2002
The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients. Nephron, 2002, Volume: 92, Issue:1 Topics: Adult; Aged; Cardiovascular Diseases; Female; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Prevalence; Renal Dialysis; Risk Factors	2002
Methylenetetrahydrofolate reductase gene C677T polymorphism, plasma homocysteine and folate in end-stage renal disease dialysis and non-dialysis patients. Nephron, 2002, Volume: 92, Issue:1 Topics: Adolescent; Adult; Age Factors; Disease Progression; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Single Nucleotide; Renal Dialysis; Risk Factors	2002
Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C-->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk. Atherosclerosis, 2002, Volume: 164, Issue:2 Topics: Adult; Analysis of Variance; Antigens, Surface; Carboxypeptidases; Cardiovascular Diseases; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Probability; Reference Values; Risk Assessment; Sensitivity and Specificity; Vitamin B 12	2002
Essential hypertension in adolescents: association with insulin resistance and with metabolism of homocysteine and vitamins. American journal of hypertension, 2002, Volume: 15, Issue:10 Pt 1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hypertension; Insulin Resistance; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prevalence; Risk Factors; Vitamin B 12; Vitamin B 6	2002
Cystathionine beta-synthase polymorphisms and hyperhomocysteinaemia: an association study. European journal of human genetics : EJHG, 2003, Volume: 11, Issue:1 Topics: Adult; Cystathionine beta-Synthase; Fasting; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Vascular Diseases	2003
The methylentetrahydrofolate reductase C677T point mutation is a risk factor for vascular access thrombosis in hemodialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:3 Topics: Arteriovenous Shunt, Surgical; Cross-Sectional Studies; Cytosine; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Renal Dialysis; Risk Factors; Thrombosis; Thymine	2003
Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults. Blood, 2003, Apr-01, Volume: 101, Issue:7 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nutritional Status; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12	2003
Gene-gene interaction between the cystathionine beta-synthase 31 base pair variable number of tandem repeats and the methylenetetrahydrofolate reductase 677C > T polymorphism on homocysteine levels and risk for neural tube defects. Molecular genetics and metabolism, 2003, Volume: 78, Issue:3 Topics: Adolescent; Adult; Child; Cystathionine beta-Synthase; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neural Tube Defects; Polymorphism, Genetic; Tandem Repeat Sequences; Vitamin B 6	2003
Genetic evidence that nitric oxide modulates homocysteine: the NOS3 894TT genotype is a risk factor for hyperhomocystenemia. Arteriosclerosis, thrombosis, and vascular biology, 2003, Jun-01, Volume: 23, Issue:6 Topics: Adult; Amino Acid Substitution; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Northern Ireland; Point Mutation; Prospective Studies; Risk Factors; Vitamin B 12	2003
The effect of methylenetetrahydrofolate reductase C677T common variant on hypertensive risk is not solely explained by increased plasma homocysteine values. Clinical and experimental hypertension (New York, N.Y. : 1993), 2003, Volume: 25, Issue:4 Topics: Aged; Blood Pressure; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Risk Factors	2003
Interaction between common folate polymorphisms and B-vitamin nutritional status modulates homocysteine and risk for a thrombotic event. Molecular genetics and metabolism, 2003, Volume: 79, Issue:3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alleles; Data Interpretation, Statistical; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Nutritional Status; Point Mutation; Polymorphism, Single Nucleotide; Prevalence; Reverse Transcriptase Polymerase Chain Reaction; Thromboembolism; Vitamin B 12; Vitamin B 12 Deficiency	2003
The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study. Thrombosis research, 2003, May-01, Volume: 110, Issue:2-3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine; Case-Control Studies; Coronary Disease; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Guanine; Homocysteine; Humans; Middle Aged; Osmolar Concentration; Risk Factors; Vitamin B 12	2003
Peroxisome proliferator-activated receptor-gamma2-Pro12Ala and endothelial nitric oxide synthase-4a/bgene polymorphisms are associated with essential hypertension. Journal of hypertension, 2003, Volume: 21, Issue:9 Topics: Aged; Blood Pressure; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hypertension; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Receptors, Cytoplasmic and Nuclear; Risk Factors; Transcription Factors	2003
Methionine synthase (MTR) 2756 (A --> G) polymorphism, double heterozygosity methionine synthase 2756 AG/methionine synthase reductase (MTRR) 66 AG, and elevated homocysteinemia are three risk factors for having a child with Down syndrome. American journal of medical genetics. Part A, 2003, Sep-01, Volume: 121A, Issue:3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alleles; Case-Control Studies; Child; Down Syndrome; Female; Ferredoxin-NADP Reductase; Flavoproteins; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Sicily	2003
The search for thrombophilic gene mutations in women with gestational hypertension does not help in predicting poor pregnancy outcome. Journal of hypertension, 2003, Volume: 21, Issue:10 Topics: Adult; Factor V; Female; Genetic Predisposition to Disease; HELLP Syndrome; Homocysteine; Humans; Hypertension; Laser-Doppler Flowmetry; Methylenetetrahydrofolate Reductase (NADPH2); Plasminogen Activator Inhibitor 1; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Prothrombin; Risk Factors; Thrombosis; Ultrasonography; Uterus	2003
Homocysteine status and polymorphisms of methylenetetrahydrofolate reductase are not associated with restenosis after stenting in coronary arteries. Arteriosclerosis, thrombosis, and vascular biology, 2003, Volume: 23, Issue:12 Topics: Aged; Coronary Artery Disease; Coronary Restenosis; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Postoperative Complications; Prosthesis Implantation; Stents; Thrombosis; Treatment Outcome; Vitamin B 12	2003
[Hyperhomocysteinemia and deep-vein thrombosis]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2003, Volume: 25, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Restriction Fragment Length; Venous Thrombosis; Vitamin B 12	2003
Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population. Journal of medical genetics, 2004, Volume: 41, Issue:4 Topics: Case-Control Studies; Epistasis, Genetic; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Neural Tube Defects; Polymorphism, Genetic; United Kingdom	2004
Determinants of arterial stiffness in offspring of families with essential hypertension. American journal of hypertension, 2004, Volume: 17, Issue:4 Topics: Adult; Aged; Biomarkers; Blood Flow Velocity; Blood Pressure; Brachial Artery; Creatinine; Family Health; Female; Genetic Predisposition to Disease; Heart Rate; Homocysteine; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Sex Factors; Statistics as Topic	2004
[Relations of methionine synthase gene variation with congenital heart disease]. Wei sheng yan jiu = Journal of hygiene research, 2004, Volume: 33, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Child; Child, Preschool; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutathione; Heart Defects, Congenital; Heart Septal Defects; Homocysteine; Humans; Infant; Male; Polymorphism, Genetic; Vitamin B 12	2004
A haplotype of the methylenetetrahydrofolate reductase gene is protective against late-onset Alzheimer's disease. Neurobiology of aging, 2004, Volume: 25, Issue:3 Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Brain; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Haplotypes; Homocysteine; Humans; Immunity, Innate; Japan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic	2004
The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma. British journal of cancer, 2004, May-17, Volume: 90, Issue:10 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Case-Control Studies; Cell Transformation, Neoplastic; Central Nervous System Neoplasms; DNA, Neoplasm; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Lymphoma; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic	2004
Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine Study. The American journal of medicine, 2004, Jul-01, Volume: 117, Issue:1 Topics: Abruptio Placentae; Adult; Alleles; Congenital Abnormalities; Female; Fetal Growth Retardation; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Humans; Logistic Models; Maternal Age; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy, High-Risk; Risk Factors	2004
New advances in identifying genetic anomalies in stroke-prone probands. Current neurology and neuroscience reports, 2004, Volume: 4, Issue:5 Topics: Anemia, Sickle Cell; Arteriosclerosis; Dementia, Multi-Infarct; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Homocysteine; Humans; Lipid Metabolism; Lipoproteins; MELAS Syndrome; Mutation; Polymorphism, Genetic; Stroke	2004
Lack of genetic dispositions to hyperhomocysteinemia in Alzheimer disease. American journal of medical genetics. Part A, 2004, Nov-15, Volume: 131, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Age Factors; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Chi-Square Distribution; Cystathionine beta-Synthase; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Genetic; Sex Factors; Survival Analysis	2004
Evidence for association between endothelial nitric oxide synthase gene polymorphism (G894T) and inflammatory markers: the ATTICA study. American heart journal, 2004, Volume: 148, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, LDL; Cross-Sectional Studies; Female; Fibrinogen; Genetic Predisposition to Disease; Homocysteine; Humans; Leukocyte Count; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Point Mutation; Polymorphism, Genetic; Serum Amyloid A Protein	2004
Hyperhomocysteinemia, enzyme polymorphism and thiobarbituric Acid reactive system in children with high coronary risk family history. Journal of the American College of Nutrition, 2004, Volume: 23, Issue:5 Topics: Adolescent; Carbon-Nitrogen Ligases; Case-Control Studies; Child; Child, Preschool; Coronary Disease; Female; Fluorometry; Genetic Markers; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Polymorphism, Restriction Fragment Length; Risk Factors; Thiobarbituric Acid Reactive Substances	2004
Methylenetetrahydrofolate reductase polymorphism associated with susceptibility to coronary heart disease in Chinese type 2 diabetic patients. Molecular and cellular endocrinology, 2005, Jan-14, Volume: 229, Issue:1-2 Topics: Asian People; Case-Control Studies; Coronary Disease; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Risk Factors	2005
Genetic polymorphisms predisposing to hyperhomocysteinemia in cardiac transplant patients. Transplant international : official journal of the European Society for Organ Transplantation, 2005, Volume: 18, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Base Sequence; DNA Primers; Ferredoxin-NADP Reductase; Genetic Predisposition to Disease; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Retrospective Studies; Thromboembolism	2005
Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke. Neurology, 2004, Dec-28, Volume: 63, Issue:12 Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Cholesterol; Dementia, Vascular; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germany; Glutathione Transferase; Homocysteine; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Point Mutation; Polymorphism, Genetic; Stroke	2004
No evidence for hyperhomocysteinemia or increased prevalence of genetic polymorphisms in the homocysteine pathway in patients with moderate juvenile idiopathic arthritis. The Journal of rheumatology, 2005, Volume: 32, Issue:1 Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; DNA; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Polymorphism, Restriction Fragment Length	2005
[Genetic mutations of homocysteine metabolism related enzymes in patients with ischemic stroke]. Yi chuan = Hereditas, 2004, Volume: 26, Issue:3 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cystathionine beta-Synthase; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Stroke	2004
Stroke and recurrent pregnancy loss due to hyperhomocysteinaemia. European journal of neurology, 2005, Volume: 12, Issue:3 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Abortion, Habitual; Brain; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Infarction, Middle Cerebral Artery; Middle Aged; Mutation; Platelet Aggregation Inhibitors; Pregnancy; Stroke; Treatment Outcome; Vitamin B 12	2005
Serum homocysteine, methylenetetrahydrofolate reductase gene polymorphism and cardiovascular disease in heterozygous familial hypercholesterolemia. Atherosclerosis, 2005, Volume: 179, Issue:2 Topics: Adult; Aged; Coronary Artery Disease; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperlipoproteinemia Type II; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Regression Analysis; Risk Factors; Sex Factors	2005
The relationships between plasma total homocysteine and selected atherosclerotic risk factors according to the C677T methylenetetrahydrofolate reductase gene in Japanese. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2005, Volume: 12, Issue:2 Topics: Adult; Aged; Arteriosclerosis; Asian People; Cross-Sectional Studies; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Genetics, Population; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Reference Values; Risk Assessment; Sensitivity and Specificity	2005
Thermolabile methylenetetrahydrofolate reductase enzyme genotype is frequent in type 2 diabetic patients with normal fasting homocysteine levels. Journal of internal medicine, 2005, Volume: 257, Issue:5 Topics: Adult; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Electrophoresis, Polyacrylamide Gel; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic	2005
Family history, plasma homocysteine, and age at onset of symptoms of myocardial ischemia in patients with different methylenetetrahydrofolate reductase genotypes. The American journal of cardiology, 2005, Jun-15, Volume: 95, Issue:12 Topics: Age of Onset; Aged; DNA; Electrophoresis, Agar Gel; Female; Genetic Markers; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Israel; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Myocardial Ischemia; Pedigree; Polymerase Chain Reaction; Regression Analysis; Risk Factors; Smoking	2005
Genetic, dietary, and other lifestyle determinants of serum homocysteine levels in young adults in Costa Rica. Revista panamericana de salud publica = Pan American journal of public health, 2005, Volume: 17, Issue:4 Topics: Adult; Cardiovascular Diseases; Costa Rica; Cross-Sectional Studies; Diet; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Life Style; Male; Risk Factors	2005
Further evidence that hyperhomocysteinemia and methylenetetrahydrofolate reductase C677T and A1289C polymorphisms are not risk factors for schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:7 Topics: Adult; Aged; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Retrospective Studies; Risk Factors; Schizophrenia; Sex Factors	2005
[Lipid metabolism and risk of myocardial infarction -- new findings and implications for treatment]. Deutsche medizinische Wochenschrift (1946), 2005, Sep-30, Volume: 130, Issue:39 Topics: Anticholesteremic Agents; C-Reactive Protein; Cholesterol, LDL; Coronary Artery Disease; Genetic Predisposition to Disease; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Myocardial Infarction; Polymorphism, Single Nucleotide; Risk Assessment	2005
Thrombophilias and stroke: diagnosis, treatment, and prognosis. Journal of thrombosis and thrombolysis, 2005, Volume: 20, Issue:2 Topics: Anticoagulants; Cystathionine beta-Synthase; Factor V; Genetic Predisposition to Disease; Genetic Testing; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Methylenetetrahydrofolate Reductase (NADPH2); Platelet Activation; Platelet Aggregation; Polymorphism, Genetic; Prognosis; Protein S Deficiency; Prothrombin; Secondary Prevention; Stroke; Thrombophilia; Warfarin	2005
[Assessment of metabolic atherosclerosis risk factors in progeny of patients with past ischemic stroke]. Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 113, Issue:2 Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Biomarkers; Brain Ischemia; C-Reactive Protein; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Female; Fibrinogen; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Life Style; Lipoprotein(a); Male; Risk Factors; Stroke; Time Factors; Triglycerides; von Willebrand Factor	2005
The influence of genetic and environmental factors on plasma homocysteine concentrations in a population at high risk for coronary artery disease. Annals of clinical biochemistry, 2005, Volume: 42, Issue:Pt 6 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Coronary Artery Disease; Cystathionine beta-Synthase; Environment; Erythrocytes; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Polymorphism, Genetic; Risk Factors; Vitamin B 12; Vitamin B 6	2005
Association of MTRRA66G polymorphism (but not of MTHFR C677T and A1298C, MTRA2756G, TCN C776G) with homocysteine and coronary artery disease in the French population. Thrombosis and haemostasis, 2005, Volume: 94, Issue:3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alleles; Case-Control Studies; Coronary Artery Disease; Female; Ferredoxin-NADP Reductase; Folic Acid; France; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Transcobalamins; Vitamin B 12; White People	2005
Methylenetetrahydrofolate reductase gene polymorphisms in essential hypertension relation: with the development of hypertensive end-stage renal disease. American journal of hypertension, 2005, Volume: 18, Issue:11 Topics: Alleles; Case-Control Studies; Cross-Sectional Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hypertension; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Predictive Value of Tests	2005
5,10-Methylenetetrahydrofolate reductase C677T gene polymorphism in Behcet's patients with or without ocular involvement. The British journal of ophthalmology, 2005, Volume: 89, Issue:12 Topics: Adult; Behcet Syndrome; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Panuveitis; Polymorphism, Genetic	2005
Migraine and MTHFR C677T genotype in a population-based sample. Annals of neurology, 2006, Volume: 59, Issue:2 Topics: Adult; Aged; Carbon-Nitrogen Ligases; Community Health Planning; Confidence Intervals; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Middle Aged; Migraine Disorders; Odds Ratio; Polymorphism, Genetic; Risk Factors; Sex Factors	2006
Homocysteine metabolism in families from southern Italy with neural tube defects: role of genetic and nutritional determinants. Prenatal diagnosis, 2006, Volume: 26, Issue:1 Topics: Adolescent; Adult; Case-Control Studies; Child, Preschool; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Infant; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Neural Tube Defects; Nutritional Status; White People	2006
Congenital heart defects, maternal homocysteine, smoking, and the 677 C>T polymorphism in the methylenetetrahydrofolate reductase gene: evaluating gene-environment interactions. American journal of obstetrics and gynecology, 2006, Volume: 194, Issue:1 Topics: Adult; Case-Control Studies; Cytosine; Female; Genetic Predisposition to Disease; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Smoking; Thymine	2006
Influence of PON1 polymorphisms on the association between serum paraoxonase 1 and homocysteinemia in a general population. Clinical chemistry, 2006, Volume: 52, Issue:4 Topics: Adult; Aged; Aryldialkylphosphatase; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Polymorphism, Genetic	2006
Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study. QJM : monthly journal of the Association of Physicians, 2006, Volume: 99, Issue:5 Topics: Adult; Factor V; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Maternal Age; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Norway; Odds Ratio; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies; Risk Factors; Smoking; Vitamin B 12	2006
The methylenetetrahydrofolate reductase C677T gene mutation is associated with hyperhomocysteinemia, cardiovascular disease and plasma B-type natriuretic peptide levels in Korea. Clinical chemistry and laboratory medicine, 2006, Volume: 44, Issue:9 Topics: Aged; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Creatine Kinase; Creatinine; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Isoenzymes; Korea; L-Lactate Dehydrogenase; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Natriuretic Peptide, Brain; Troponin I	2006
Pediatric stroke, homocysteine and MTHFR 677C-T and 1298 A-C. Journal of pediatric hematology/oncology, 2006, Volume: 28, Issue:9 Topics: Age Factors; Child; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Genetic; Risk Factors; Stroke	2006
Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss. Annals of hematology, 2007, Volume: 86, Issue:1 Topics: Abortion, Habitual; Adolescent; Adult; Aged; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Thrombosis; Vitamin B 12	2007
Methylenetetrahydrofolate reductase gene polymorphism, homocysteine and risk of macroangiopathy in Type 2 diabetes mellitus. Journal of endocrinological investigation, 2006, Volume: 29, Issue:9 Topics: Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Regression Analysis	2006
Plasma vitamin values and antiepileptic therapy: case reports of pregnancy outcomes affected by a neural tube defect. Birth defects research. Part A, Clinical and molecular teratology, 2007, Volume: 79, Issue:1 Topics: Adult; Anticonvulsants; Epilepsy; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Valproic Acid; Vitamin B 12; Vitamin B 6	2007
The association of homocysteine and its determinants MTHFR genotype, folate, vitamin B12 and vitamin B6 with bone mineral density in postmenopausal British women. Bone, 2007, Volume: 40, Issue:3 Topics: Aged; Alcohol Drinking; Bone Density; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Osteoporosis, Postmenopausal; Polymorphism, Genetic; Postmenopause; Smoking; Vitamin B 12; Vitamin B 6; White People	2007
Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer. Cancer letters, 2007, Jun-28, Volume: 251, Issue:2 Topics: Aged; Carboxypeptidases; Case-Control Studies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Stomach Neoplasms; Vitamin B 12	2007
Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms. Arquivos de neuro-psiquiatria, 2006, Volume: 64, Issue:4 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Female; Genetic Markers; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic	2006
Relationship of the 1793G-A and 677C-T polymorphisms of the 5,10-methylenetetrahydrofolate reductase gene to coronary artery disease. Disease markers, 2006, Volume: 22, Issue:5-6 Topics: Coronary Artery Disease; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Polymorphism, Genetic	2006
Functional COMT Val158Met polymorphism, risk of acute coronary events and serum homocysteine: the Kuopio ischaemic heart disease risk factor study. PloS one, 2007, Jan-31, Volume: 2, Issue:1 Topics: Adult; Catechol O-Methyltransferase; Cohort Studies; Coronary Disease; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Ischemia; Polymorphism, Genetic; Prospective Studies; Risk Factors	2007
Associations of MTHFR DNMT3b 4977 bp deletion in mtDNA and GSTM1 deletion, and aberrant CpG island hypermethylation of GSTM1 in non-obstructive infertility in Indian men. Molecular human reproduction, 2007, Volume: 13, Issue:4 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Base Sequence; Case-Control Studies; CpG Islands; Deoxyguanosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA, Mitochondrial; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Glutathione Transferase; Homocysteine; Humans; India; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Sequence Deletion; Vitamin B 12; White People	2007
Influence of MTHFR genotype on contingent negative variation and MRI abnormalities in migraine. Headache, 2007, Volume: 47, Issue:2 Topics: Adolescent; Adult; Case-Control Studies; Contingent Negative Variation; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Homozygote; Humans; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Migraine Disorders; Risk Factors; Stroke	2007
Medical-process patents. The New England journal of medicine, 2007, Feb-15, Volume: 356, Issue:7 Topics: Delivery of Health Care; Genetic Predisposition to Disease; Homocysteine; Humans; Patents as Topic; Pharmacogenetics; Supreme Court Decisions; United States; Vitamin B 12	2007
Polymorphisms in the methylenetetrahydrofolate reductase gene are determinant for vascular complications after liver transplantation. European journal of clinical nutrition, 2008, Volume: 62, Issue:3 Topics: Chromatography, High Pressure Liquid; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Liver Transplantation; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Retrospective Studies; Risk Factors; Vascular Diseases	2008
Relationship of vascular risk to the progression of Alzheimer disease. Neurology, 2007, Mar-27, Volume: 68, Issue:13 Topics: Alzheimer Disease; Apolipoproteins E; Cerebral Arteries; Cerebrovascular Disorders; Cholesterol; Disease Progression; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperlipidemias; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors	2007
Monocyte chemoattractant protein-1: plasma concentrations and A(-2518)G promoter polymorphism of its gene in systemic lupus erythematosus. The Journal of rheumatology, 2007, Volume: 34, Issue:4 Topics: Adult; Black or African American; Calcinosis; Case-Control Studies; Chemokine CCL2; Coronary Vessels; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Lupus Erythematosus, Systemic; Middle Aged; Nephritis; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; White People	2007
Apolipoprotein E polymorphism, homocysteine serum levels and hippocampal volume in patients with alcoholism: an investigation of a gene-environment interaction. The pharmacogenomics journal, 2008, Volume: 8, Issue:2 Topics: Adult; Alcoholism; Apolipoprotein E4; Environment; Female; Gene Frequency; Genetic Predisposition to Disease; Hippocampus; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Organ Size; Polymorphism, Genetic; Risk Factors	2008
Associations of common polymorphisms in the thymidylate synthase, reduced folate carrier and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase genes with folate and homocysteine levels and venous thrombosis Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:4 Topics: Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hydroxymethyl and Formyl Transferases; Membrane Transport Proteins; Multienzyme Complexes; Nucleotide Deaminases; Polymorphism, Genetic; Reduced Folate Carrier Protein; Thymidylate Synthase; Venous Thrombosis	2007
[Correlation between serum homocysteine levels and selected atherosclerosis risk factors in children and adolescents with simple obesity]. Przeglad lekarski, 2006, Volume: 63, Issue:8 Topics: Adolescent; Atherosclerosis; Biomarkers; Body Mass Index; Child; Comorbidity; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hypertension; Male; Obesity; Obesity, Morbid; Poland; Risk Factors; Statistics, Nonparametric; Vitamin B 12	2006
Endothelial cell dysfunction in women with cardiac syndrome X and MTHFR C677T mutation. The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:4 Topics: Axillary Artery; DNA; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Female; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Microvascular Angina; Middle Aged; Mutation; Ultrasonography; Vasodilation	2007
Contribution of methylenetetrahydrofolate reductase (MTHFR) polymorphisms to negative symptoms in schizophrenia. Biological psychiatry, 2008, Jan-01, Volume: 63, Issue:1 Topics: Adult; Analysis of Variance; Behavioral Symptoms; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Psychiatric Status Rating Scales; Pteroylpolyglutamic Acids; Risk; Schizophrenia; Schizophrenic Psychology	2008
Mild hyperhomocysteinemia and low folate concentrations as risk factors for cervical arterial dissection. Cerebrovascular diseases (Basel, Switzerland), 2007, Volume: 24, Issue:2-3 Topics: Adolescent; Adult; Carotid Artery, Internal, Dissection; Case-Control Studies; Cerebral Arteries; Cerebral Infarction; Fasting; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Middle Aged; Nutritional Status; Odds Ratio; Polymorphism, Genetic; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Vertebral Artery Dissection; Vitamin B 12	2007
Genetically based hypertension generated through interaction of mild hypoalphalipoproteinemia and mild hyperhomocysteinemia. Journal of hypertension, 2007, Volume: 25, Issue:8 Topics: Animals; Base Sequence; DNA Primers; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Hypertension; Lipoproteins, HDL; Male; Mice	2007
Influence of 677 C-->T polymorphism of methylenetetrahydrofolate reductase on medium-term prognosis after acute coronary syndromes. Texas Heart Institute journal, 2007, Volume: 34, Issue:2 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Female; Follow-Up Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Kaplan-Meier Estimate; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Syndrome; Time Factors	2007
Polymorphisms of apolipoprotein e and methylenetetrahydrofolate reductase in the Japanese population. Journal of atherosclerosis and thrombosis, 2007, Volume: 14, Issue:4 Topics: Apolipoproteins E; Asian People; Data Collection; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Japan; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Sex Distribution	2007
The paraoxonase gene polymorphism in stroke patients and lipid profile. Acta neurologica Scandinavica, 2008, Volume: 117, Issue:4 Topics: Aged; Apolipoproteins B; Aryldialkylphosphatase; Brain Ischemia; Cholesterol, LDL; DNA Mutational Analysis; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Intracranial Arteriosclerosis; Lipid Metabolism; Male; Middle Aged; Polymorphism, Genetic; Stroke	2008
Relationship between estrogen receptor-alpha polymorphism and serum levels of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, C-reactive protein and homocysteine in postmenopausal women. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2007, Volume: 23, Issue:10 Topics: Aged; C-Reactive Protein; Cohort Studies; Estrogen Receptor alpha; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Intercellular Adhesion Molecule-1; Middle Aged; Polymorphism, Genetic; Postmenopause; Vascular Cell Adhesion Molecule-1	2007
Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption. American journal of obstetrics and gynecology, 2007, Volume: 197, Issue:4 Topics: Abruptio Placentae; Adolescent; Adult; Alleles; Case-Control Studies; DNA; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Linkage Disequilibrium; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pregnancy; Social Class; Vitamin B 12	2007
[The relationship between polymorphism of gene involved in folate metabolism, homocysteine level and risk of Down syndrome]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2007, Volume: 24, Issue:5 Topics: Adult; Alleles; Base Sequence; Case-Control Studies; Down Syndrome; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Pregnancy	2007
5,10-methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease. Acta neurologica Taiwanica, 2007, Volume: 16, Issue:3 Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic	2007
Are genetic variants of the methyl group metabolism enzymes risk factors predisposing to obesity? Journal of endocrinological investigation, 2007, Volume: 30, Issue:9 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Cystathionine beta-Synthase; Ferredoxin-NADP Reductase; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Leptin; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Obesity; Odds Ratio; Polymorphism, Genetic; Risk Factors	2007
Association of polymorphism in the thermolabile 5, 10-methylene tetrahydrofolate reductase gene and hyperhomocysteinemia with coronary artery disease. Molecular and cellular biochemistry, 2008, Volume: 310, Issue:1-2 Topics: Coronary Artery Disease; Enzyme Stability; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Phenotype; Polymorphism, Single Nucleotide; Regression Analysis	2008
Methylenetetrahydrofolate reductase 677 T allele protects against persistent HBV infection in West Africa. Journal of hepatology, 2008, Volume: 48, Issue:4 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Alleles; Benin; Biomarkers; DNA; DNA Probes; DNA, Viral; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; HLA-DR Antigens; HLA-DRB1 Chains; Homocysteine; Humans; Immunoassay; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Morbidity; Polymerase Chain Reaction; Polymorphism, Genetic; Vitamin B 12	2008
Evidence of major genes effects on serum homocysteine and fibrinogen levels, and premature ischemic heart disease in Italian extended families. Human heredity, 2008, Volume: 66, Issue:1 Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Fibrinogen; Genetic Predisposition to Disease; Homocysteine; Humans; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Myocardial Ischemia; Parents; Pedigree; Polymorphism, Single Nucleotide; Risk Factors; Siblings	2008
Role of methylenetetrahydrofolate reductase 677C->T polymorphism in the development of premature myocardial infarction. Atherosclerosis, 2008, Volume: 200, Issue:1 Topics: Adult; Case-Control Studies; Coronary Angiography; Coronary Vessels; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Infarction; Odds Ratio; Polymorphism, Single Nucleotide	2008
Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease. Neurobiology of aging, 2009, Volume: 30, Issue:10 Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Apolipoprotein E4; China; Female; Folic Acid; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk Factors; Sex Factors	2009
Prospective study of homocysteine and MTHFR 677TT genotype and risk for venous thrombosis in a general population--results from the HUNT 2 study. British journal of haematology, 2008, Volume: 141, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Epidemiologic Methods; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pulmonary Embolism; Venous Thrombosis	2008
Protective effect against alcohol dependence of the thermolabile variant of MTHFR. Drug and alcohol dependence, 2008, Jul-01, Volume: 96, Issue:1-2 Topics: Alcohol Drinking; Alcoholic Neuropathy; Alcoholism; Control Groups; Female; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Vitamin B 12	2008
Challenges in identifying genetic risk factors for common multifactorial disorders. The Indian journal of medical research, 2008, Volume: 127, Issue:2 Topics: Alleles; Genetic Diseases, Inborn; Genetic Predisposition to Disease; Genetic Variation; Homocysteine; Homozygote; Humans; India; Mutation; Polymorphism, Genetic; Risk Factors	2008
Plasma homocysteine levels & 677C-->T methylenetetrahydrofolate reductase gene polymorphism in patients with coronary artery disease of different severity. The Indian journal of medical research, 2008, Volume: 127, Issue:2 Topics: Aged; Atherosclerosis; Coronary Artery Disease; Demography; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic	2008
Polymorphisms in genes related to folate and cobalamin metabolism and the associations with complex birth defects. Prenatal diagnosis, 2008, Volume: 28, Issue:6 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amniotic Fluid; Case-Control Studies; Child; Congenital Abnormalities; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Risk Factors; Transcobalamins; Vitamin B 12	2008
Thymidylate synthase genotype and serum concentrations of homocysteine and folate in Behçet's disease. Clinical rheumatology, 2008, Volume: 27, Issue:10 Topics: Adolescent; Adult; Behcet Syndrome; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Middle Aged; Promoter Regions, Genetic; Tandem Repeat Sequences; Thymidylate Synthase; Venous Thrombosis; Young Adult	2008
Hypermethioninaemia due to methionine adenosyltransferase I/III (MAT I/III) deficiency: diagnosis in an expanded neonatal screening programme. Journal of inherited metabolic disease, 2008, Volume: 31 Suppl 2 Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Child Development; Child, Preschool; Early Diagnosis; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methionine Adenosyltransferase; Mutation; Neonatal Screening; Pedigree; Phenotype; Predictive Value of Tests; Prognosis; Spain; Tandem Mass Spectrometry; Up-Regulation	2008
V677 mutation of methylenetetrahydrofolate reductases and cardiovascular disease in Canadian Inuit. Lancet (London, England), 1997, Apr-26, Volume: 349, Issue:9060 Topics: Adult; Alleles; Canada; Cardiovascular Diseases; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Inuit; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Prevalence	1997
Search for genetic factors favoring thrombosis in Turkish population. Thrombosis research, 1998, Oct-15, Volume: 92, Issue:2 Topics: Case-Control Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Mutation; Thrombosis; Turkey	1998
The results of diagnostic studies for thrombophilia in a large group of patients with a personal or family history of thrombosis. American journal of clinical pathology, 1998, Volume: 110, Issue:5 Topics: Activated Protein C Resistance; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Anticoagulants; Child; Child, Preschool; Factor V; Genetic Predisposition to Disease; Homocysteine; Humans; Lupus Coagulation Inhibitor; Middle Aged; Mutation; Thrombophilia; Thrombophlebitis; Thrombosis	1998
Homozygous G20210A prothrombin gene mutation without thromboembolic events: a case report. Thrombosis and haemostasis, 1998, Volume: 80, Issue:6 Topics: 3' Untranslated Regions; Adult; Aged; Brain Ischemia; Female; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Male; Methionine; Middle Aged; Prothrombin; Risk Factors; Thrombophilia; Thrombophlebitis	1998
Is the oral methionine loading test insensitive to the remethylation pathway of homocysteine? Blood, 1999, Feb-01, Volume: 93, Issue:3 Topics: Artifacts; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Reproducibility of Results; Risk Factors; Thrombophilia	1999
[A young patient with chronic recurrent leg ulcers; hyperhomocysteinemia and heterozygote for factor V Leiden]. Nederlands tijdschrift voor geneeskunde, 1998, Dec-05, Volume: 142, Issue:49 Topics: Adult; Anticoagulants; Bandages; Chronic Disease; Factor V; Folic Acid; Genetic Carrier Screening; Genetic Predisposition to Disease; Homocysteine; Humans; Leg Ulcer; Male; Metabolism, Inborn Errors; Secondary Prevention; Venous Thrombosis	1998
[A hyperhomocysteinemia study in a population with a familial factor for acute myocardial infarct and sudden cardiac death at a young age]. Cardiologia (Rome, Italy), 1999, Volume: 44, Issue:1 Topics: Adult; Age Factors; Aged; Case-Control Studies; Chi-Square Distribution; Death, Sudden, Cardiac; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Middle Aged; Myocardial Infarction; Risk Factors; Sex Characteristics	1999
Homocysteine and arteriosclerosis: subclinical and clinical disease associations. Circulation, 1999, May-11, Volume: 99, Issue:18 Topics: Adolescent; Adult; Animals; Arteriosclerosis; Child; Child, Preschool; Comorbidity; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Middle Aged; Prevalence; Primates; Risk Factors; Swine; Swine, Miniature; Thrombophilia	1999
Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS) Circulation, 1999, May-11, Volume: 99, Issue:18 Topics: Adult; Aged; Amino Acid Substitution; Arteriosclerosis; Carotid Arteries; Carotid Stenosis; Comorbidity; Diet; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Obesity; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Pyridoxine; Risk Factors; Smoking; Tunica Intima; Ultrasonography; Vitamin B 12; Western Australia	1999
Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease. Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:5 Topics: Adult; Age Factors; Amino Acid Substitution; Arteriosclerosis; Body Mass Index; Comorbidity; Fasting; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipids; Male; Menopause; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pyridoxine; Smoking; Vitamin B 12	1999
Genetic determinants of heritable venous thrombosis: genotyping methods for factor V(Leiden)A1691G, methylenetetrahydrofolate reductase C677T, prothrombin G20210A mutation, and algorithms for venous thrombosis investigations. Clinical biochemistry, 1999, Volume: 32, Issue:3 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Algorithms; Base Sequence; DNA Primers; Factor V; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases; Polymerase Chain Reaction; Prothrombin; Venous Thrombosis	1999
The 677T genotype of the common MTHFR thermolabile variant and fasting homocysteine in childhood venous thrombosis. European journal of pediatrics, 1999, Volume: 158 Suppl 3 Topics: Adolescent; Age of Onset; Alleles; Case-Control Studies; Child; Child, Preschool; Factor V; Female; Genetic Predisposition to Disease; Genotype; Germany; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multifactorial Inheritance; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Prothrombin; Risk Factors; Statistics, Nonparametric; Venous Thrombosis	1999
Methylenetetrahydrofolate reductase 677 C --> T polymorphism, plasma folate, vitamin B(12) concentrations, and risk of preeclampsia among black African women from Zimbabwe. Molecular genetics and metabolism, 2000, Volume: 69, Issue:1 Topics: Adolescent; Adult; Alleles; Black People; Case-Control Studies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nutritional Physiological Phenomena; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Risk Factors; Vitamin B 12; Zimbabwe	2000
Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677T and A1298C mutations. American journal of human genetics, 2000, Volume: 67, Issue:4 Topics: Abortion, Habitual; Alleles; Female; Fetal Blood; Fetal Death; Fetus; Gene Frequency; Genes, Essential; Genes, Lethal; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Phenotype; Point Mutation; Polymorphism, Genetic; Pregnancy; Pregnancy Outcome	2000
Are fasting plasma homocyst(e)ine levels heritable? A study of normotensive twins. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2000, Volume: 48, Issue:5 Topics: Adult; DNA; Fasting; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Polymerase Chain Reaction; Twins, Dizygotic; Twins, Monozygotic	2000
The association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients. The Journal of nutrition, 2000, Volume: 130, Issue:10 Topics: Aged; Albuminuria; Alleles; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors	2000
The influence of age, sex, vitamin B(12), folate levels and methylenetetrahydrofolate reductase C677T genetic mutations on plasma homocysteine in the Chinese population. Haematologica, 2000, Volume: 85, Issue:10 Topics: Age Factors; Aged; China; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Sex Factors; Thromboembolism; Vitamin B 12	2000
Effect of heterozygosity for the methionine synthase 2756 A-->G mutation on the risk for recurrent cardiovascular events. The American journal of cardiology, 2000, Nov-15, Volume: 86, Issue:10 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Disease-Free Survival; Erythrocytes; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Humans; Incidence; Male; Middle Aged; Mutation; Myocardial Infarction; Polymorphism, Genetic; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Recurrence; Risk Factors	2000
Abdominal venous thrombosis in neonates and infants: role of prothrombotic risk factors - a multicentre case-control study. For the Childhood Thrombophilia Study Group. British journal of haematology, 2000, Volume: 111, Issue:2 Topics: Antibodies, Anticardiolipin; Antithrombins; Budd-Chiari Syndrome; Case-Control Studies; Confidence Intervals; Factor V; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Infant; Infant, Newborn; Lipoprotein(a); Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Portal Vein; Prospective Studies; Protein C; Protein S; Prothrombin; Renal Veins; Venous Thrombosis	2000
Methylenetetrahydrofolate reductase genotypes and predisposition to atherothrombotic disease; evidence that all three MTHFR C677T genotypes confer different levels of risk. European heart journal, 2001, Volume: 22, Issue:4 Topics: Coronary Artery Disease; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors	2001
Racial variation in fasting and random homocysteine levels. American journal of hematology, 2001, Volume: 66, Issue:4 Topics: Black People; Blood Urea Nitrogen; Body Mass Index; Creatinine; Fasting; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; New York City; Personnel, Hospital; Random Allocation; Reference Values; Time Factors; Vitamin B 12; White People	2001
Homozygous thermolabile variant of the methylenetetrahydrofolate reductase gene: a potential risk factor for hyperhomocysteinaemia, CVD, and stroke in childhood. Developmental medicine and child neurology, 2001, Volume: 43, Issue:4 Topics: Adolescent; Alleles; Cerebrovascular Disorders; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Infant; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Recurrence; Risk Factors; Stroke; Temperature	2001
Mutation A1298C of methylenetetrahydrofolate reductase: risk for early coronary disease not associated with hyperhomocysteinemia. American journal of medical genetics, 2001, Jun-01, Volume: 101, Issue:1 Topics: Adolescent; Adult; Age of Onset; Alleles; Case-Control Studies; Coronary Disease; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Homozygote; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prevalence; Risk Factors	2001
The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations. Atherosclerosis, 2001, Volume: 157, Issue:2 Topics: Adult; Ferredoxin-NADP Reductase; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osmolar Concentration; Polymorphism, Genetic	2001
[Relationship between methylenetetrahydrofolate reductase gene polymorphism and diabetic nephropathy]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2001, Volume: 18, Issue:4 Topics: Asian People; Diabetic Nephropathies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length	2001
Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases. Thrombosis research, 2001, Nov-01, Volume: 104, Issue:3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Arterial Occlusive Diseases; Case-Control Studies; Cerebrovascular Disorders; China; Coronary Artery Disease; Cystathionine beta-Synthase; Enzymes; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Myocardial Infarction; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic	2001
A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk. Journal of molecular medicine (Berlin, Germany), 2001, Volume: 79, Issue:9 Topics: Adult; Cardiovascular Diseases; Fasting; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors	2001
[The association of methylenetetrahydrofolate reductase gene polymorphism with nephropathy in type 2 diabetes mellitus in Chinese]. Zhonghua nei ke za zhi, 2001, Volume: 40, Issue:8 Topics: Adult; Alleles; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic	2001
Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice. Toxicology and applied pharmacology, 2001, Dec-15, Volume: 177, Issue:3 Topics: Animals; Arsenates; Arsenicals; Arsenites; Cacodylic Acid; Carrier Proteins; Dose-Response Relationship, Drug; Female; Fetal Resorption; Folate Receptors, GPI-Anchored; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Mice; Mice, Knockout; Neural Tube Defects; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Cell Surface; Teratogens	2001
Assessment of prothrombotic risk in patients with Behçet's disease should include homocysteine plasma levels. The Journal of rheumatology, 2001, Volume: 28, Issue:12 Topics: Behcet Syndrome; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Thromboembolism; Vitamin B 12; Vitamin B 6	2001
Hyperhomocysteinemia and other inherited prothrombotic conditions in young adults with a history of ischemic stroke. Stroke, 2002, Volume: 33, Issue:1 Topics: Adult; Brain Ischemia; Factor V; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prothrombin; Risk Factors; Stroke; Venous Thrombosis	2002
Red blood cell methylfolate and plasma homocysteine as risk factors for venous thromboembolism: a matched case-control study. Lancet (London, England), 2002, Mar-02, Volume: 359, Issue:9308 Topics: Adult; Aged; Case-Control Studies; Erythrocytes; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Pulmonary Embolism; Risk Factors; Tetrahydrofolates; Venous Thrombosis	2002
[Hyperhomocysteine, methylenetetrahydrofolate reductase gene, and other risk factors in ischemic stroke]. Zhonghua yi xue za zhi, 2002, Jan-25, Volume: 82, Issue:2 Topics: Asian People; Brain Ischemia; Female; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Prognosis; Risk Factors; Smoking	2002
Lp(a), homocysteine and a family history of early ischemic cerebral stroke. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2001, Volume: 11 Suppl 5 Topics: Adolescent; Adult; Brain Ischemia; Factor VII; Female; Fibrinogen; Genetic Predisposition to Disease; Homocysteine; Humans; Lipoprotein(a); Male; Middle Aged; Regression Analysis; Risk Factors; Severity of Illness Index; Stroke; Uric Acid	2001
Methionine synthase polymorphism A2756G is associated with susceptibility for thromboembolic events and altered B vitamin/thiol metabolism. Haematologica, 2002, Volume: 87, Issue:7 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Genetic Predisposition to Disease; Glutathione; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Prevalence; Sulfhydryl Compounds; Thromboembolism; Vitamin B 12	2002