homocysteine and Diabetic Retinopathy

homocysteine has been researched along with Diabetic Retinopathy in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (14.52)	18.2507
2000's	24 (38.71)	29.6817
2010's	17 (27.42)	24.3611
2020's	12 (19.35)	2.80

Authors

Authors	Studies
Shi, Y; Song, X; Sun, W; Yang, J; Zhang, W; Zhang, Y; Zhou, X	1
Bulum, T; Ljubić, S; Rahelić, D; Tomić, M; Vrabec, R	1
Fu, J; Zhu, J	1
Chen, X; Fung, AT; Gong, Z; Nie, Y; Qiu, B; Sivaprasad, S; Wang, Q; Wang, Y; Xie, R; Zhang, X	1
Fang, ZZ; Gao, XQ; Jiang, CT; Liu, X; Luo, WM; Su, JY; Wang, WY; Zhang, W; Zhang, ZP	1
Dong, J; Guo, G; Jin, M; Li, D; Li, X; Nan, J; Zhang, X	1
Bakthavatsalam, M; Brelen, ME; Chan, KP; Chan, TI; Chu, KO; Pang, CP; Wang, CC; Yip, YW	1
Cheng, W; Guo, J; Huang, AM; Li, H; Liang, J; Liu, C; Liu, Z; Wang, W; Yang, R; Zhang, J	1
Gu, J; Lei, C; Zhang, M	1
Al-Shabrawey, M; Alhusban, S; Elsherbiny, NM; Jadeja, R; Kira, D; Martin, P; Samra, YA; Sharma, I; Tawfik, A	1
Kowluru, RA; Mohammad, G	1
Al-Shabrawey, M; Elsherbiny, NM; Samra, YA; Tawfik, A	1
Gupta, P; John, D; John, SS; Rebekah, G	1
Aizawa, T; Funase, Y; Ouchi, K; Sato, Y; Yamauchi, K	1
Blaslov, K; Bulum, T; Duvnjak, L	1
Avitabile, T; Bucolo, C; Caraci, F; Drago, F; Gagliano, C; Giordano, M; Malaguarnera, G; Motta, M; Reibaldi, M; Salomone, S; Vacante, M	1
Apergis, G; Dimitriadis, G; Fotiou, P; Raptis, A; Theodossiadis, P; Vergados, I	1
Kayadibi, H; Sertoglu, E; Uyanik, M	1
Liu, G; Liu, X; Wang, F; Wu, Y; Xu, C; Yu, J	1
Anichini, R; Bianchi, L; Campesi, I; Carru, C; De Bellis, A; Franconi, F; Napoli, Z; Occhioni, S; Seghieri, G; Zinellu, A	1
Hernández, C; Simó, R; Simó-Servat, O	1
Akduman, L; Khanna, VK; Mahdi, AA; Meyer, CH; Saxena, S; Shukla, RK; Srivastav, K	1
Angayarkanni, N; Bharathselvi, M; Coral, K; Gomathy, N; Pukhraj, R; Rupak, R	1
Alibrahim, E; Cotch, MF; Islam, FM; Klein, BE; Klein, R; Nguyen, TT; Shea, S; Wong, TY	1
Brazionis, L; Itsiopoulos, C; Jenkins, A; O'Dea, K; Rowley, K; Wong, TY; Yau, J	1
Angayarkanni, N; Barathi, S; Dhupper, M; Muralidharan, C; Natarajan, SK; Pasupathi, A; Pukraj, R; Sivashanmugham, M; Velpandian, T	1
Klein, BE; Klein, R; Myers, CE; Sahakyan, K; Tsai, MY	1
Chang, HH; Chen, BY; Chen, YS; Lin, DP; Lin, W; Liu, HJ; Teng, MC; Tsao, ZJ	1
Ayyagari, R; Balakrishna, N; Lopamudra, P; Mudili, S; Pitla, S; Reddy, GB; Reddy, PY; Satyanarayana, A; Suryanarayana, P; Viswanath, K	1
Hassan, M; Khang, TF; Khaw, KW; Lim, CP; Loo, AV; Sthaneshwar, P; Subrayan, V	1
Ayata, A; Özcan, Ö; Yildirim, Y	1
Guo, Q; Lu, J; Pan, C	1
Agulló-Ortuño, MT; Albaladejo, MD; Fenollar, M; Martínez, P; Parra, S; Rodríguez-Manotas, M; Ruíz-Espejo, F; Tebar, J	1
Abdella, NA; Akanji, AO; Mojiminiyi, OA; Moussa, MA	1
Cinapri, V; Fagnani, F; Giampietro, O; Mariani, S; Matteucci, E; Quilici, S; Rossi, L	1
Deng, H; Fan, Y; Lu, H; Sun, J; Sun, S; Xu, Y; Zhang, Y; Zhu, Y	2
Fagot-Campagna, A; Gunter, EW; Hanson, RL; Knowler, WC; Looker, HC; Narayan, KM; Pfeiffer, CM	1
Nixon, SJ; Saeed, BO; Skillen, AW; Summerfield, GP; Weaver, JU; White, AJ	1
Gavendo, S; Goldstein, M; Leibovitch, I; Loewenstein, A; Sela, BA; Yeffimov, I	1
Elias, AN; Eng, S	1
Müftüoglu, F; Yücel, G; Yücel, I	1
Chaturvedi, N; Fuller, JH; Idzior-Walus, B; Soedamah-Muthu, SS; Stehouwer, CD; Teerlink, T	1
Chang, MH; Chen, TH; Chen, YJ; Hsu, HH; Huang, CY; Huang, EJ; Kuo, WW; Lee, SD; Lu, MC; Tzang, BS	1
Brazionis, L; Harper, CA; Itsiopoulos, C; O'Dea, K; Rowley, K	1
Bouter, LM; Dekker, JM; Heine, RJ; Jakobs, C; Nijpels, G; Polak, BC; Stehouwer, CD; Stolk, RP; Teerlink, T; Van Hecke, MV	1
Aydemir, O; Celiker, U; Güler, M; Metin, K; Türkçüoğlu, P; Ustündağ, B; Yilmaz, T	1
Agardh, CD; Agardh, E; Andersson, A; Hultberg, B	1
Ellis, JM; McCully, KS	1
Baba, T; Kurokawa, K; Neugebauer, S; Watanabe, T	1
Greco, G; Ingrosso, D; Riccardi, G; Rivellese, A; Vaccaro, O	1
Agardh, CD; Agardh, E; Hultberg, B; Lövestam-Adrian, M	1
Arcelús, R; Blanco-Vaca, F; Carreras, G; Chico, A; Córdoba, A; de Leiva, A; González-Sastre, F; Pérez, A	1
Odekerken, DA; Rakic, M; Sijbrands, EJ; Silberbusch, J; Slaats, EH; Smulders, YM; Stehouwer, CD; Treskes, M	1
Fiedor, P; Polakowska, MJ; Socha, MW; Socha-Urbanek, K	1
Agardh, CD; Agardh, E; Hultberg, B	1
Cuomo, V; Ingrosso, D; Mancini, FP; Perna, AF; Riccardi, G; Rivellese, AA; Sacco, M; Tufano, A; Vaccaro, O	1
Chiarelli, F; Mohn, A; Morgese, G; Pomilio, M; Spagnoli, A; Tumini, S; Vanelli, M; Verrotti, A	1
Cuomo, V; Ingrosso, D; Iovine, C; Mancini, FP; Perna, AF; Riccardi, G; Rivellese, AA; Sacco, M; Tufano, A; Vaccaro, O	1
Buysschaert, M; Dramais, AS; Hermans, MP; Jamart, J; Wallemacq, P	1
Lu, J; Pan, C; Yang, G	1
Agardh, CD; Agardh, E; Andersson, A; Brattström, L; Hultberg, B; Isaksson, A; Israelsson, B	1

Reviews

6 review(s) available for homocysteine and Diabetic Retinopathy

Article	Year
Folate and retinal vascular diseases. BMC ophthalmology, 2023, Oct-13, Volume: 23, Issue:1 Topics: Diabetic Retinopathy; Endothelial Cells; Folic Acid; Glucose; Homocysteine; Humans; Hyperhomocysteinemia; Methionine	2023
Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction. Biomolecules, 2020, 07-29, Volume: 10, Issue:8 Topics: Aging; Alzheimer Disease; Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Endoplasmic Reticulum Stress; Homocysteine; Humans; Hyperhomocysteinemia; Macular Degeneration; Oxidative Stress	2020
Relationship between homocysteine level and diabetic retinopathy: a systematic review and meta-analysis. Diagnostic pathology, 2014, Sep-26, Volume: 9 Topics: Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Homocysteine; Humans; Risk Factors	2014
Circulating Biomarkers of Diabetic Retinopathy: An Overview Based on Physiopathology. Journal of diabetes research, 2016, Volume: 2016 Topics: Adrenomedullin; Arginine; Autoantibodies; Basement Membrane; Biomarkers; C-Reactive Protein; Collagen Type IV; Diabetic Retinopathy; E-Selectin; Endothelial Progenitor Cells; Extracellular Matrix; Glycation End Products, Advanced; Homocysteine; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Laminin; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; MicroRNAs; Retinol-Binding Proteins, Plasma; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2016
Homocysteine concentrations in patients with diabetes mellitus--relationship to microvascular and macrovascular disease. Diabetes, obesity & metabolism, 2005, Volume: 7, Issue:2 Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Homocysteine; Humans; Insulin; Microcirculation	2005
Hyperhomocysteinemia as a risk factor for cardiovascular diseases. The association of hyperhomocysteinemia with diabetes mellitus and renal transplant recipients. Annals of transplantation, 1999, Volume: 4, Issue:1 Topics: Cardiovascular Diseases; Diabetes Complications; Diabetic Nephropathies; Diabetic Retinopathy; Endothelium, Vascular; Heart Transplantation; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Risk Factors	1999

Trials

1 trial(s) available for homocysteine and Diabetic Retinopathy

Article	Year
Homocysteine serum levels in diabetic patients with non proliferative, proliferative and without retinopathy. BioMed research international, 2014, Volume: 2014 Topics: Adult; Aged; Aged, 80 and over; Blindness; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Middle Aged	2014

Other Studies

55 other study(ies) available for homocysteine and Diabetic Retinopathy

Article	Year
Transthyretin and retinol-binding protein as discriminators of diabetic retinopathy in type 1 diabetes mellitus. International ophthalmology, 2022, Volume: 42, Issue:4 Topics: Apolipoproteins B; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Homocysteine; Humans; Prealbumin; Retinol-Binding Proteins, Plasma; Retrospective Studies; Triglycerides; Uric Acid	2022
Plasma homocysteine is associated with nonproliferative retinopathy in patients with type 2 diabetes without renal disease. Diabetes & metabolic syndrome, 2022, Volume: 16, Issue:1 Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Folic Acid; Homocysteine; Humans; Vitamin B 12	2022
Relationship among Serum Homocysteine, Intercellular Adhesion Molecule-1, Monocyte Chemoattractant Protein-1, and Visual Impairment in Diabetic Macular Edema. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2022, Volume: 32, Issue:1 Topics: Chemokine CCL2; Cross-Sectional Studies; Diabetes Mellitus; Diabetic Retinopathy; Homocysteine; Humans; Intercellular Adhesion Molecule-1; Macular Edema; Vision, Low	2022
Circulating level of homocysteine contributes to diabetic retinopathy associated with dysregulated lipid profile and impaired kidney function in patients with type 2 diabetes mellitus. Eye (London, England), 2023, Volume: 37, Issue:7 Topics: Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Homocysteine; Humans; Kidney	2023
The Association of Homocysteine and Diabetic Retinopathy in Homocysteine Cycle in Chinese Patients With Type 2 Diabetes. Frontiers in endocrinology, 2022, Volume: 13 Topics: Asian People; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Homocysteine; Humans; Methionine; Risk Factors	2022
Effect of Leptin Levels of Type 2 Diabetes Mellitus and Diabetic Complications. Clinical and investigative medicine. Medecine clinique et experimentale, 2022, 09-21, Volume: 45, Issue:3 Topics: Albumins; Biomarkers; Body Mass Index; Cholesterol, HDL; Cystatin C; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Estradiol; Female; Homocysteine; Humans; Leptin; Male; Polyesters; Testosterone; Triglycerides	2022
Untargeted metabolomic analysis of aqueous humor in diabetic macular edema. Molecular vision, 2022, Volume: 28 Topics: Antioxidants; Aqueous Humor; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Fatty Acids; Glucose; Homocysteine; Homovanillic Acid; Humans; Inflammation; Macular Edema; Prostaglandins; Sorbitol	2022
The association of homocysteine level with the risk of diabetic nephropathy and diabetic retinopathy in NHANES. Acta diabetologica, 2023, Volume: 60, Issue:7 Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Homocysteine; Humans; Kidney Function Tests; Nutrition Surveys; Risk Factors	2023
Homocysteine Induces Inflammation in Retina and Brain. Biomolecules, 2020, 03-03, Volume: 10, Issue:3 Topics: Alzheimer Disease; Animals; Brain; Diabetic Retinopathy; Homocysteine; Humans; Inflammation; Macular Degeneration; Mice; Mice, Knockout; Retina; U937 Cells	2020
Homocysteine Disrupts Balance between MMP-9 and Its Tissue Inhibitor in Diabetic Retinopathy: The Role of DNA Methylation. International journal of molecular sciences, 2020, Mar-05, Volume: 21, Issue:5 Topics: Animals; Apoptosis; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; DNA Methylation; Endothelial Cells; Gene Expression Regulation; Homocysteine; Male; Matrix Metalloproteinase 1; Oxidative Stress; Rats; Rats, Wistar; Retinal Vessels; Tissue Inhibitor of Metalloproteinase-1	2020
Role of hyperhomocysteinemia in proliferative diabetic retinopathy: A case-control study. Indian journal of ophthalmology, 2018, Volume: 66, Issue:10 Topics: Adult; Aged; Blood Glucose; Case-Control Studies; Diabetic Retinopathy; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged	2018
Relationship between metformin use, vitamin B12 deficiency, hyperhomocysteinemia and vascular complications in patients with type 2 diabetes. Endocrine journal, 2013, Volume: 60, Issue:12 Topics: Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Japan; Male; Metformin; Middle Aged; Prevalence; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 12 Deficiency	2013
Plasma Homocysteine is Associated with Retinopathy in Type 1 Diabetic Patients in the Absence of Nephropathy. Seminars in ophthalmology, 2016, Volume: 31, Issue:3 Topics: Adult; Aged; Albuminuria; Blood Glucose; Creatinine; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Young Adult	2016
Vitamin status as a determinant of serum homocysteine concentration in type 2 diabetic retinopathy. Journal of diabetes research, 2014, Volume: 2014 Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Prevalence; Regression Analysis; Risk Factors; Vitamin B 12; Vitamins	2014
Plasma total homocysteine levels in diabetic retinopathy. BioMed research international, 2014, Volume: 2014 Topics: Blindness; Diabetic Retinopathy; Female; Homocysteine; Humans; Male	2014
Taurine Transporter Gene Expression in Mononuclear Blood Cells of Type 1 Diabetes Patients. Journal of diabetes research, 2016, Volume: 2016 Topics: Adult; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Endothelium, Vascular; Female; Glycated Hemoglobin; Homocysteine; Humans; Leukocytes, Mononuclear; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Oxidative Stress; RNA, Messenger; Up-Regulation	2016
Increased serum level of homocysteine correlates with retinal nerve fiber layer thinning in diabetic retinopathy. Molecular vision, 2016, Volume: 22 Topics: Adult; Aged; Cross-Sectional Studies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nerve Fibers; Prospective Studies; Retinal Ganglion Cells; Tomography, Optical Coherence; Vitamin B 12	2016
Homocysteine levels in the vitreous of proliferative diabetic retinopathy and rhegmatogenous retinal detachment: its modulating role on lysyl oxidase. Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:8 Topics: Adult; Aged; Chromatography, High Pressure Liquid; Collagen; Diabetic Retinopathy; Female; Homocysteine; Humans; Hydroxyproline; Male; Middle Aged; Protein-Lysine 6-Oxidase; Retinal Detachment; Vitreous Body; Young Adult	2009
Inflammatory, hemostatic, and other novel biomarkers for diabetic retinopathy: the multi-ethnic study of atherosclerosis. Diabetes care, 2009, Volume: 32, Issue:9 Topics: Aged; Albuminuria; alpha-2-Antiplasmin; Atherosclerosis; C-Reactive Protein; Creatinine; Diabetic Retinopathy; Factor VIII; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Homocysteine; Humans; Interleukin-6; Male; Middle Aged; Pancreatitis-Associated Proteins	2009
Plasminogen activator inhibitor-1 (PAI-1) activity and retinal vascular calibre in type 2 diabetes. Diabetes research and clinical practice, 2010, Volume: 87, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Arterioles; Blood Glucose; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Female; Glycated Hemoglobin; Heart Rate; Homocysteine; Humans; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Regression Analysis; Retinal Artery; Retinal Vein; Retinal Vessels; Risk Factors; Venules; Waist-Hip Ratio	2010
Homocysteinethiolactone and paraoxonase: novel markers of diabetic retinopathy. Diabetes care, 2010, Volume: 33, Issue:9 Topics: Aged; Aryldialkylphosphatase; Cells, Cultured; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Middle Aged; Retinal Perforations; Tandem Mass Spectrometry; Vitreous Body	2010
Novel risk factors in long-term hypertension incidence in type 1 diabetes mellitus. American heart journal, 2010, Volume: 159, Issue:6 Topics: Adult; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Homocysteine; Humans; Hypertension; Incidence; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Middle Aged; Odds Ratio; Prognosis; Retrospective Studies; Risk Factors; Time Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Wisconsin	2010
Intravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors. Molecular vision, 2011, Volume: 17 Topics: Animals; Calbindins; Diabetic Retinopathy; Dose-Response Relationship, Drug; Eye Proteins; Female; Glial Fibrillary Acidic Protein; Homeodomain Proteins; Homocysteine; Hyperhomocysteinemia; Immunoblotting; Immunohistochemistry; Intravitreal Injections; LIM-Homeodomain Proteins; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Paired Box Transcription Factors; PAX6 Transcription Factor; Photoreceptor Cells; Repressor Proteins; Retina; Retinal Degeneration; Retinal Ganglion Cells; Rhodopsin; S100 Calcium Binding Protein G; Transcription Factors	2011
Status of B-vitamins and homocysteine in diabetic retinopathy: association with vitamin-B12 deficiency and hyperhomocysteinemia. PloS one, 2011, Volume: 6, Issue:11 Topics: Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Diabetic Retinopathy; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Risk Factors; Vitamin B 12 Deficiency; Vitamin B Complex	2011
Plasma, aqueous and vitreous homocysteine levels in proliferative diabetic retinopathy. The British journal of ophthalmology, 2012, Volume: 96, Issue:5 Topics: Adult; Aged; Aqueous Humor; Case-Control Studies; Diabetic Retinopathy; Female; Homocysteine; Humans; Hypercholesterolemia; Hypertension; Kidney Diseases; Luminescent Measurements; Male; Middle Aged; Myocardial Ischemia; Stroke; Vitreous Body	2012
Comment on: 'Plasma, aqueous and vitreous homocysteine levels in proliferative diabetic retinopathy'. The British journal of ophthalmology, 2012, Volume: 96, Issue:8 Topics: Aqueous Humor; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Vitreous Body	2012
[The abnormal reaction to post methionine loading test in type diabetes with or without retinopathy]. Zhonghua yi xue za zhi, 2002, Jun-10, Volume: 82, Issue:11 Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Nitrates; Oxidoreductases Acting on CH-NH Group Donors; Time Factors	2002
Plasmatic homocysteine concentration and its relationship with complications associated to diabetes mellitus. Clinica chimica acta; international journal of clinical chemistry, 2002, Volume: 326, Issue:1-2 Topics: Adult; Aged; Analysis of Variance; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis	2002
Associations of plasma homocysteine concentration in subjects with type 2 diabetes mellitus. Acta diabetologica, 2002, Volume: 39, Issue:4 Topics: Albuminuria; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osmolar Concentration	2002
Blood levels of total homocysteine in patients with type 1 diabetes (with no complications, diabetic nephropathy and/or retinopathy) and in their non-diabetic relatives. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2002, Volume: 12, Issue:4 Topics: Adult; Aged; Case-Control Studies; Creatinine; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Middle Aged; Sex Factors; Smoking	2002
The relationship between MTHFR gene polymorphisms, plasma homocysteine levels and diabetic retinopathy in type 2 diabetes mellitus. Chinese medical journal, 2003, Volume: 116, Issue:1 Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic	2003
[The relationship of methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine levels in type 2 diabetes mellitus patients with diabetic retinopathy]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2003, Volume: 20, Issue:2 Topics: Adult; Alleles; Deoxyribonucleases, Type II Site-Specific; Diabetes Mellitus, Type 2; Diabetic Retinopathy; DNA; Female; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic	2003
Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes. Diabetologia, 2003, Volume: 46, Issue:6 Topics: Age Factors; Analysis of Variance; Arizona; Biomarkers; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Incidence; Indians, North American; Longitudinal Studies; Male; Middle Aged; Vitamin B 12	2003
Fasting homocysteine levels in adults with type 1 diabetes and retinopathy. Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 341, Issue:1-2 Topics: Aged; Albuminuria; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Endothelium, Vascular; Female; Homocysteine; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Thrombomodulin	2004
Hyperhomocysteinemia in patients with diabetes mellitus with and without diabetic retinopathy. Eye (London, England), 2004, Volume: 18, Issue:5 Topics: Aged; Blood Glucose; Cardiovascular Diseases; Case-Control Studies; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Prospective Studies; Time Factors	2004
Plasma homocysteine levels in noninsulin-dependent diabetes mellitus with retinopathy and neovascular glaucoma. International ophthalmology, 2004, Volume: 25, Issue:4 Topics: Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Glaucoma, Neovascular; Homocysteine; Humans; Middle Aged; Risk Factors	2004
Plasma homocysteine and microvascular and macrovascular complications in type 1 diabetes: a cross-sectional nested case-control study. Journal of internal medicine, 2005, Volume: 258, Issue:5 Topics: Adult; Albuminuria; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Retinopathy; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hypertension; Male; Microcirculation; Prospective Studies; Risk Factors	2005
Homocysteine and other biochemical parameters in Type 2 diabetes mellitus with different diabetic duration or diabetic retinopathy. Clinica chimica acta; international journal of clinical chemistry, 2006, Volume: 366, Issue:1-2 Topics: Aged; Albuminuria; Bilirubin; Biomarkers; Blood Glucose; C-Reactive Protein; Chromatography, High Pressure Liquid; Creatine Kinase; Creatinine; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycated Hemoglobin; Homocysteine; Humans; L-Lactate Dehydrogenase; Lipids; Male; Middle Aged; Time Factors; Uric Acid	2006
Homocysteine and diabetic retinopathy. Diabetes care, 2008, Volume: 31, Issue:1 Topics: Adult; Aged; Biomarkers; Blood Pressure; Cross-Sectional Studies; Diabetic Retinopathy; Female; Fluorescein Angiography; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Life Style; Male; Middle Aged; Odds Ratio; Risk Factors	2008
Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study. Clinical science (London, England : 1979), 2008, Volume: 114, Issue:7 Topics: Aged; Aged, 80 and over; Arterioles; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Folic Acid; Follow-Up Studies; Glucose Tolerance Test; Homocysteine; Humans; Male; Middle Aged; Retinal Diseases; Retinal Vessels; S-Adenosylhomocysteine; S-Adenosylmethionine	2008
Plasma and vitreous homocysteine concentrations in patients with proliferative diabetic retinopathy. Retina (Philadelphia, Pa.), 2008, Volume: 28, Issue:5 Topics: Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Homocysteine; Humans; Laser Coagulation; Male; Middle Aged; Vitrectomy; Vitreous Body	2008
Lack of association between plasma homocysteine levels and microangiopathy in type 1 diabetes mellitus. Scandinavian journal of clinical and laboratory investigation, 1994, Volume: 54, Issue:8 Topics: Adult; Albuminuria; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12	1994
Prevention of myocardial infarction by vitamin B6. Research communications in molecular pathology and pharmacology, 1995, Volume: 89, Issue:2 Topics: Aged; Aged, 80 and over; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Pyridoxine; Retrospective Studies; Rheumatic Diseases; Texas; Vitamin B Deficiency	1995
Defective homocysteine metabolism as a risk factor for diabetic retinopathy. Lancet (London, England), 1997, Feb-15, Volume: 349, Issue:9050 Topics: Diabetic Retinopathy; Homocysteine; Humans; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length	1997
Moderate hyperhomocysteinaemia and retinopathy in insulin-dependent diabetes. Lancet (London, England), 1997, Apr-12, Volume: 349, Issue:9058 Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation	1997
Poor metabolic control, early age at onset, and marginal folate deficiency are associated with increasing levels of plasma homocysteine in insulin-dependent diabetes mellitus. A five-year follow-up study. Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:7 Topics: Adult; Age of Onset; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12	1997
Plasma homocysteine is related to albumin excretion rate in patients with diabetes mellitus: a new link between diabetic nephropathy and cardiovascular disease? Diabetologia, 1998, Volume: 41, Issue:6 Topics: Adult; Aged; Albuminuria; Analysis of Variance; Biomarkers; Body Mass Index; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Proteinuria; Regression Analysis; Vitamins	1998
Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and cardiovascular disease. Diabetes care, 1999, Volume: 22, Issue:1 Topics: Administration, Oral; Adult; Aged; Albuminuria; Analysis of Variance; Blood Pressure; Cardiovascular Diseases; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Postmenopause; Premenopause; Pyridoxal Phosphate; Regression Analysis; Risk Factors; Vitamin B 12	1999
Severe retinopathy in type 1 diabetic patients is not related to the level of plasma homocysteine. Scandinavian journal of clinical and laboratory investigation, 2000, Volume: 60, Issue:3 Topics: Adult; Albuminuria; Creatinine; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Glycated Hemoglobin; Homocysteine; Humans; Male	2000
Plasma homocysteine and its determinants in diabetic retinopathy. Diabetes care, 2000, Volume: 23, Issue:7 Topics: Biomarkers; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Folic Acid; Gene Frequency; Homocysteine; Homozygote; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Vitamin B 12	2000
Homocysteine levels during fasting and after methionine loading in adolescents with diabetic retinopathy and nephropathy. The Journal of pediatrics, 2000, Volume: 137, Issue:3 Topics: Adolescent; Adult; Age of Onset; Albuminuria; Child; Cholesterol, LDL; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Fasting; Female; Homocysteine; Humans; Lipoprotein(a); Male; Methionine; Regression Analysis; Statistics, Nonparametric	2000
Plasma homocysteine and microvascular complications in type 1 diabetes. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2000, Volume: 10, Issue:6 Topics: Adult; Albuminuria; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Vitamin B 12	2000
Micro- and macrovascular complications and hyperhomocysteinaemia in type 1 diabetic patients. Diabetes & metabolism, 2001, Volume: 27, Issue:6 Topics: Adult; Aging; Blood Pressure; Cholesterol; Cholesterol, HDL; Creatinine; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Retinopathy; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Time Factors	2001
[The impact of plasma homocysteine level on development of retinopathy in type 2 diabetes mellitus]. Zhonghua nei ke za zhi, 2002, Volume: 41, Issue:1 Topics: Adult; Aged; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Severity of Illness Index	2002
Increased levels of plasma homocysteine are associated with nephropathy, but not severe retinopathy in type 1 diabetes mellitus. Scandinavian journal of clinical and laboratory investigation, 1991, Volume: 51, Issue:3 Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Middle Aged	1991