homocysteine and Diabetic Angiopathies

homocysteine has been researched along with Diabetic Angiopathies in 75 studies

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (17.33)18.2507
2000's50 (66.67)29.6817
2010's11 (14.67)24.3611
2020's1 (1.33)2.80

Authors

AuthorsStudies
Chen, S; Fu, G; Wang, Y; Xu, T; Yang, F; Zhang, K; Zhang, W1
Chen, L; Chen, YM; Ling, WH; Tan, YZ; Wang, LJ; Wei, J; Yang, Y; Zhou, JY; Zhu, HL1
Aizawa, T; Funase, Y; Ouchi, K; Sato, Y; Yamauchi, K1
Akalin, A; Arabul, M; Celik, M; Cerrah, S1
Barbieri, L; Cassetti, E; De Luca, G; Schaffer, A; Suryapranata, H; Verdoia, M1
Ates, I; Barca, AN; Cetin, M; Kiziltunc, E; Kundi, H; Ornek, E; Ozkayar, N1
Chen, WB; Lin, YZ; Lv, D; Xie, F1
Couper, JJ; Peña, AS1
Dou, J; Gu, W; Lu, J; Meng, J; Mu, Y; Pan, C; Yang, G1
Beigel, Y; Boaz, M; Fux, A; Hanah, R; Mashavi, M; Matas, Z; Pasternak, S; Shargorodsky, M1
Ran, XW; Yu, TT1
Bayindir, O; Görmüş, U; Mutaf, I; Ozdoğan, O; Ozmen, B; Ozmen, D; Parildar, Z1
Brazionis, L; Itsiopoulos, C; Jenkins, A; O'Dea, K; Rowley, K; Wong, TY; Yau, J1
Bartegi, A; López, JJ; Redondo, PC; Rosado, JA; Salido, GM; Zbidi, H1
Farbstein, D; Levy, AP1
Incampa, S; Jaiyen, S; Khaithong, W; Saokaew, S; Sridetch, S; Sudchada, P1
Abdella, N; Akanji, AO; Al Mohammedi, H; Mojiminiyi, OA; Moussa, MA; Zaki, M1
Angelini, GD; Jeremy, JY; Shukla, N2
Ghitescu, L; Gugliucci, A1
Andersson, A; Hultberg, B; Jonasson, T; Lindgren, A; Ohlin, H1
Baba, T; Neugebauer, S; Parving, HH; Stehouwer, C; Tarnow, L; Teerlink, T; Watanabe, T1
Agulló-Ortuño, MT; Albaladejo, MD; Fenollar, M; Martínez, P; Parra, S; Rodríguez-Manotas, M; Ruíz-Espejo, F; Tebar, J1
Fonseca, VA; Theuma, P1
Fagot-Campagna, A; Gunter, EW; Hanson, RL; Knowler, WC; Looker, HC; Narayan, KM; Pfeiffer, CM1
Aso, Y; Inukai, T; Okumura, K; Takebayashi, K; Wakabayashi, S1
Cucinotta, D; Russo, GT1
Aso, Y; Okumura, K1
Ajabnoor, MA; AL-Ama, MN; Banjar, Z; Rafee, AA; Sheweita, SA1
Clement, L1
Liu, M; Yan, C; Zhu, C1
Frohlich, J; Genest, J; Steiner, G1
Demircin, M; Guvener, M; Haznedaroglu, IC; Ozkan, M; Pasaoglu, I; Yilmaz, M1
Cuervo, R; Kitabchi, AE; Stentz, FB; Umpierrez, GE1
Botezat, M; Cojocaru, IM; Druţă, A; Muşuroi, C; Oprişan, A; Uscatescu, V1
Becker, A; Bouter, LM; Dekker, JM; Heine, RJ; Henry, RM; Jakobs, C; Kostense, PJ; Nijpels, G; Smulders, YM; Spijkerman, AM; Stehouwer, CD; Teerlink, T1
Gallagher, A; Home, PD1
Elias, AN; Eng, S1
Kinalska, I; Kowalska, I; Rudy, A; Straczkowski, M1
Bostom, AG; Friedman, AN; Hunsicker, LG; Selhub, J1
Borgiel-Marek, H; Gatnar, A; Gnot, R; Januła, A; Kajdaniuk, D; Kos-Kudła, B; Marek, B; Sierek, K; Strzyzewski, A; Wyrwas-Bełz, U; Zeka, G1
Chaturvedi, N; Fuller, JH; Idzior-Walus, B; Soedamah-Muthu, SS; Stehouwer, CD; Teerlink, T1
Borni, Z; Brahim, N; Chahib, M; Habib, H; Hédi, M; Olfa, E; Oudi, M; Salem, M; Zied, A1
Amayo, EO; Ogola, EN; Otieno, CF; Vaghela, V1
Aboyans, V; Criqui, MH; Denenberg, JO; Fronek, A; Knoke, JD; Ridker, PM1
Lu, H; Sun, J; Xu, Y; Zhu, Y1
Allard, SE; Browne, DL; Cummings, MH; Laight, DW; Meeking, DR; Munday, LJ; Shaw, KM; Turner, C; Wotherspoon, F1
Alaveras, A; Harris, F; Kalofoutis, A; Kalofoutis, C; Phoenix, D; Piperi, C; Singh, J; Zisaki, A1
Holland, P; Mathai, M; Radford, SE1
Fukushima, M; Inagaki, N; Kitatani, N; Kuroe, A; Nagasaka, S; Nakai, Y; Ohgushi, M; Ohya, M; Seino, Y; Taniguchi, A1
Bots, ML; Grobbee, DE; Muller, M; Nakhai-Pour, HR; van der Schouw, YT1
Araki, A; Ito, H; Sako, Y1
Fink, L; Fonseca, V; Munshi, MN; Stone, A1
Aljada, A; Baliga, BS; Dandona, P; Fink, L; Fonseca, VA; Munshi, M; Stone, A; Thusu, K1
Colwell, JA1
Amiral, J; Bierhaus, A; Borcea, V; Fiehn, W; Henkels, M; Hofmann, MA; Kohl, B; Nawroth, PP; Wahl, P; Ziegler, R; Zumbach, MS1
Amiral, J; Bierhaus, A; Borcea, V; Fiehn, W; Henkels, M; Hofmann, MA; Kohl, B; Nawroth, PP; Schmidt, AM; Wahl, P; Ziegler, R; Zumbach, MS1
Arcelús, R; Blanco-Vaca, F; Carreras, G; Chico, A; Córdoba, A; de Leiva, A; González-Sastre, F; Pérez, A1
Bloomgarden, ZT1
Astorri, E; Craveri, A; Dall'Aglio, P; Fiorina, P; Lanfredini, M; Mello, A; Peca, MG; Veronelli, A1
Barry, DG; Cronin, CC; Ferriss, JB; McPartlin, JM; Scott, JM; Weir, DG1
Brouwer, CB; Silberbusch, J; Smulders, YM1
Ammaturo, V; Andreotti, F; Bianco, P; Cortese, C; Federici, G; Mazza, A; Motti, C; Nulli, A; Pastore, A; Santoro, E1
Levy, J; Ragatzki, P; Rajkumar, V; Sima, A1
Fukuda, S; Ichikawa, H; Makino, H; Nagake, Y; Oishi, K; Ota, K; Yamasaki, H1
Calzoni, F; Carantoni, M; D'Elia, K; Fellin, R; Pareschi, PL; Passaro, A; Solini, A1
Buysschaert, M; Dramais, AS; Hermans, MP; Wallemacq, PE1
Brown, WV1
Bald, E; Chwatko, G; Czupryniak, L; Drzewoski, J1
Cuomo, V; Ingrosso, D; Iovine, C; Mancini, FP; Perna, AF; Riccardi, G; Rivellese, AA; Sacco, M; Tufano, A; Vaccaro, O1
Cassader, M; Cavallo-Perin, P; Gai, M; Gambino, R; Lillaz, E; Pagano, G; Rolfo, E; Scaglione, L1
Buysschaert, M; Dramais, AS; Hermans, MP; Jamart, J; Wallemacq, P1
Al-Attas, O; Al-Daghri, N; Al-Maatouq, M; Al-Nozah, M; Bartlett, WA; Jones, AF; Kumar, S; Martin, SC1
Burke, V; Kaye, JM; McCann, VJ; Stanton, KG; Taylor, RR; van Bockxmeer, FM; Vasikaran, SD1
Asnani, S; Desouza, C; Fonseca, V; Homan, J; McNamara, DB; Murthy, SN1

Reviews

8 review(s) available for homocysteine and Diabetic Angiopathies

ArticleYear
The genetics of vascular complications in diabetes mellitus.
    Cardiology clinics, 2010, Volume: 28, Issue:3

    Topics: Aryldialkylphosphatase; Blood Vessels; Cardiovascular Diseases; Diabetic Angiopathies; Haptoglobins; Homocysteine; Humans; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Polymorphism, Genetic; Retrospective Studies

2010
Effect of folic acid supplementation on plasma total homocysteine levels and glycemic control in patients with type 2 diabetes: a systematic review and meta-analysis.
    Diabetes research and clinical practice, 2012, Volume: 98, Issue:1

    Topics: Aged; Blood Glucose; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dietary Supplements; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Vitamin B Complex

2012
Inflammation and emerging risk factors in diabetes mellitus and atherosclerosis.
    Current diabetes reports, 2003, Volume: 3, Issue:3

    Topics: Arteriosclerosis; Biomarkers; C-Reactive Protein; Diabetes Mellitus; Diabetic Angiopathies; Homocysteine; Humans; Inflammation; Obesity; Risk Factors

2003
[Hyperhomocysteinemia and cardiovascular risk in diabetes mellitus].
    Annali dell'Istituto superiore di sanita, 2003, Volume: 39, Issue:2

    Topics: Adult; Arteriosclerosis; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Thrombophilia

2003
Homocysteine concentrations in patients with diabetes mellitus--relationship to microvascular and macrovascular disease.
    Diabetes, obesity & metabolism, 2005, Volume: 7, Issue:2

    Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Homocysteine; Humans; Insulin; Microcirculation

2005
[Homocysteine and diabetes].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2005, Volume: 58, Issue:5-6

    Topics: Arteriosclerosis; Diabetes Complications; Diabetic Angiopathies; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors

2005
Risk factors for vascular disease in patients with diabetes.
    Diabetes, obesity & metabolism, 2000, Volume: 2 Suppl 2

    Topics: Diabetic Angiopathies; Homocysteine; Humans; Hyperglycemia; Hyperlipidemias; Hypertension; Insulin Resistance; Models, Cardiovascular; Obesity; Risk Factors; Smoking; Thrombophilia

2000
Hormones and homocysteine.
    Minerva endocrinologica, 2002, Volume: 27, Issue:3

    Topics: Diabetic Angiopathies; Homocysteine; Hormones; Humans; Hyperhomocysteinemia; Hyperlipidemias; Methionine; Vascular Diseases

2002

Trials

8 trial(s) available for homocysteine and Diabetic Angiopathies

ArticleYear
Vitamin supplementation normalizes total plasma homocysteine concentration but not plasma homocysteine redox status in patients with acute coronary syndromes and hyperhomocysteinemia.
    Clinical chemistry and laboratory medicine, 2002, Volume: 40, Issue:6

    Topics: Acute Disease; Aged; Blood Pressure; Body Mass Index; Coronary Disease; Diabetic Angiopathies; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reference Values; Vitamins

2002
High plasma homocysteine concentrations are associated with plasma concentrations of thrombomodulin in patients with type 2 diabetes and link diabetic nephropathy to macroangiopathy.
    Metabolism: clinical and experimental, 2003, Volume: 52, Issue:11

    Topics: Aged; Blood Glucose; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Endothelium, Vascular; Female; Homocysteine; Humans; Male; Middle Aged; Regression Analysis; Thrombomodulin

2003
Effect of fenofibrate-mediated increase in plasma homocysteine on the progression of coronary artery disease in type 2 diabetes mellitus.
    The American journal of cardiology, 2004, Apr-01, Volume: 93, Issue:7

    Topics: Aged; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Fenofibrate; Homocysteine; Humans; Hypolipidemic Agents; Male; Middle Aged

2004
S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:4

    Topics: Aged; Brachial Artery; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nitroglycerin; Regional Blood Flow; Risk Factors; S-Adenosylmethionine; Tetrahydrofolates; Ultrasonography; Vasodilation; Vasodilator Agents; Vitamin B 12; Vitamin B 6

2005
The effect of improved post-prandial blood glucose control on post-prandial metabolism and markers of vascular risk in people with Type 2 diabetes.
    Diabetes research and clinical practice, 2005, Volume: 67, Issue:3

    Topics: Aged; Blood Glucose; Blood Glucose Self-Monitoring; Body Mass Index; Cholesterol; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Insulin Aspart; Lipoproteins; Male; Postprandial Period; Risk Factors

2005
Total plasma homocysteine and arteriosclerotic outcomes in type 2 diabetes with nephropathy.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:11

    Topics: Aged; Amlodipine; Antihypertensive Agents; Arteriosclerosis; Biphenyl Compounds; Cardiovascular System; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Double-Blind Method; Female; Homocysteine; Humans; Irbesartan; Male; Middle Aged; Placebos; Risk Factors; Smoking; Tetrazoles; Treatment Outcome

2005
Serum homocysteine, MTHFR gene polymorphism, and carotid intimal-medial thickness in NIDDM subjects.
    Journal of thrombosis and thrombolysis, 1999, Volume: 8, Issue:3

    Topics: Arteriosclerosis; Carotid Artery, Common; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Predictive Value of Tests; Regression Analysis; Risk Factors; Tunica Intima; Tunica Media; Ultrasonography

1999
Hyperhomocysteinemia in poorly controlled type 2 diabetes patients.
    Diabetes, nutrition & metabolism, 2000, Volume: 13, Issue:6

    Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Risk Factors

2000

Other Studies

59 other study(ies) available for homocysteine and Diabetic Angiopathies

ArticleYear
The impact of homocysteine on the risk of coronary artery diseases in individuals with diabetes: a Mendelian randomization study.
    Acta diabetologica, 2021, Volume: 58, Issue:3

    Topics: Case-Control Studies; Causality; Coronary Artery Disease; Diabetes Mellitus; Diabetic Angiopathies; Genetic Predisposition to Disease; Genome-Wide Association Study; Homocysteine; Humans; Linkage Disequilibrium; Mendelian Randomization Analysis; Meta-Analysis as Topic; Metabolic Networks and Pathways; Odds Ratio; Polymorphism, Single Nucleotide

2021
Higher homocysteine and lower betaine increase the risk of microangiopathy in patients with diabetes mellitus carrying the GG genotype of PEMT G774C.
    Diabetes/metabolism research and reviews, 2013, Volume: 29, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Betaine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Genotype; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide

2013
Relationship between metformin use, vitamin B12 deficiency, hyperhomocysteinemia and vascular complications in patients with type 2 diabetes.
    Endocrine journal, 2013, Volume: 60, Issue:12

    Topics: Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Japan; Male; Metformin; Middle Aged; Prevalence; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 12 Deficiency

2013
Relation of asymmetric dimethylarginine levels to macrovascular disease and inflammation markers in type 2 diabetic patients.
    Journal of diabetes research, 2014, Volume: 2014

    Topics: Aged; Arginine; Atherosclerosis; Biomarkers; Blood Sedimentation; C-Reactive Protein; Carotid Intima-Media Thickness; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Fibrinogen; Homocysteine; Humans; Inflammation Mediators; Male; Middle Aged; Regression Analysis; Systemic Vasculitis; Up-Regulation

2014
Impact of Diabetes on Homocysteine Levels and Its Relationship with Coronary Artery Disease: A Single-Centre Cohort Study.
    Annals of nutrition & metabolism, 2016, Volume: 68, Issue:3

    Topics: Age Factors; Aged; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Diabetic Angiopathies; Diabetic Cardiomyopathies; Diabetic Nephropathies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Hypertriglyceridemia; Italy; Male; Middle Aged; Prevalence; Renal Insufficiency; Risk Factors; Severity of Illness Index; Smoking

2016
Association between plasma homocysteine levels and end-organ damage in newly diagnosed type 2 diabetes mellitus patients.
    Endocrine research, 2017, Volume: 42, Issue:1

    Topics: Aged; Carotid Artery Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Diabetic Nephropathies; Female; Homocysteine; Humans; Male; Middle Aged

2017
[Correlation of homocysteine with diabetic microangiopathy and the change after drug intervention].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2016, Nov-20, Volume: 36, Issue:11

    Topics: Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Homocysteine; Humans; Lipids; Risk Factors

2016
Folate, homocysteine, and candidate genes for vascular disease in children with type 1 diabetes.
    Pediatric diabetes, 2008, Volume: 9, Issue:4 Pt 2

    Topics: Child; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vascular Diseases

2008
Plasma homocysteine thiolactone associated with risk of macrovasculopathy in Chinese patients with type 2 diabetes mellitus.
    Advances in therapy, 2008, Volume: 25, Issue:9

    Topics: Age Factors; Asian People; Body Mass Index; China; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Middle Aged; Risk Factors; Smoking; Time Factors; Vitamin B 12

2008
Serum homocysteine, folate, vitamin B12 levels and arterial stiffness in diabetic patients: which of them is really important in atherogenesis?
    Diabetes/metabolism research and reviews, 2009, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Atherosclerosis; Biomarkers; Body Mass Index; Creatinine; Diabetes Mellitus; Diabetic Angiopathies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Models, Biological; Overweight; Regression Analysis; Vitamin B 12

2009
[Changes of plasma total homocysteine in type I diabetic patients its association with diabetic vascular complications].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2008, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Homocysteine; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Young Adult

2008
Serum N-terminal-pro-brain natriuretic peptide (NT-pro-BNP) and homocysteine levels in type 2 diabetic patients with asymptomatic left ventricular diastolic dysfunction.
    Diabetes research and clinical practice, 2010, Volume: 87, Issue:1

    Topics: Blood Pressure; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diastole; Echocardiography; Echocardiography, Transesophageal; Female; Homocysteine; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Ventricular Dysfunction, Left; Ventricular Function, Left

2010
Plasminogen activator inhibitor-1 (PAI-1) activity and retinal vascular calibre in type 2 diabetes.
    Diabetes research and clinical practice, 2010, Volume: 87, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arterioles; Blood Glucose; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Female; Glycated Hemoglobin; Heart Rate; Homocysteine; Humans; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Regression Analysis; Retinal Artery; Retinal Vein; Retinal Vessels; Risk Factors; Venules; Waist-Hip Ratio

2010
Homocysteine induces caspase activation by endoplasmic reticulum stress in platelets from type 2 diabetics and healthy donors.
    Thrombosis and haemostasis, 2010, Volume: 103, Issue:5

    Topics: Apoptosis; Blood Donors; Blood Platelets; Calcium Signaling; Caspase 3; Caspase 9; Cells, Cultured; Cinnamates; Diabetes Mellitus, Type 2; Diabetic Angiopathies; eIF-2 Kinase; Endoplasmic Reticulum; Enzyme Activation; Homocysteine; Humans; Hyperhomocysteinemia; Stress, Physiological; Thiourea

2010
Association of C-reactive protein with coronary heart disease risk factors in patients with type 2 diabetes mellitus.
    Diabetes research and clinical practice, 2002, Volume: 58, Issue:1

    Topics: Apolipoproteins; Biomarkers; Blood Glucose; Blood Pressure; C-Reactive Protein; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Homocysteine; Humans; Interleukin-6; Lipoproteins; Male; Middle Aged; Multivariate Analysis; N-Acetylneuraminic Acid; Regression Analysis; Risk Factors

2002
Homocysteine and cardiovascular disease in diabetes mellitus.
    Atherosclerosis, 2002, Volume: 164, Issue:2

    Topics: Animals; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Female; Homocysteine; Hyperhomocysteinemia; Male; Nitric Oxide; Rabbits; Rats; Rats, Inbred Strains; Risk Factors; Sensitivity and Specificity; Severity of Illness Index

2002
Is diabetic hypercoagulability an acquired annexinopathy? Glycation of annexin II as a putative mechanism for impaired fibrinolysis in diabetic patients.
    Medical hypotheses, 2002, Volume: 59, Issue:3

    Topics: Animals; Annexin A2; Clinical Trials, Phase III as Topic; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Fibrinolysis; Glycation End Products, Advanced; Glycosylation; Homocysteine; Hyperhomocysteinemia; Lipoprotein(a); Plasminogen; Risk Factors; Thrombophilia; Tissue Plasminogen Activator

2002
Total plasma homocysteine is associated with hypertension in Type I diabetic patients.
    Diabetologia, 2002, Volume: 45, Issue:9

    Topics: Adult; Albuminuria; Body Mass Index; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Female; Genotype; Glomerular Filtration Rate; Homocysteine; Humans; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Factors

2002
Plasmatic homocysteine concentration and its relationship with complications associated to diabetes mellitus.
    Clinica chimica acta; international journal of clinical chemistry, 2002, Volume: 326, Issue:1-2

    Topics: Adult; Aged; Analysis of Variance; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis

2002
Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes.
    Diabetologia, 2003, Volume: 46, Issue:6

    Topics: Age Factors; Analysis of Variance; Arizona; Biomarkers; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Incidence; Indians, North American; Longitudinal Studies; Male; Middle Aged; Vitamin B 12

2003
Relationships of plasma interleukin-18 concentrations to hyperhomocysteinemia and carotid intimal-media wall thickness in patients with type 2 diabetes.
    Diabetes care, 2003, Volume: 26, Issue:9

    Topics: Biomarkers; C-Reactive Protein; Carotid Arteries; Carotid Stenosis; Cholesterol; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Homocysteine; Humans; Hyperhomocysteinemia; Interleukin-18; Middle Aged; Reference Values; Tunica Intima; Tunica Media

2003
To: Looker HC, Fagot-Campagna A, Gunter EW et al. (2003) Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes. Diabetologia 46:766-772.
    Diabetologia, 2004, Volume: 47, Issue:1

    Topics: Animals; Diabetic Angiopathies; Diabetic Nephropathies; Homocysteine; Humans; Hyperhomocysteinemia; Models, Animal; Rabbits; Risk Factors

2004
Homocysteine level and other biochemical parameters in cardiovascular disease patients with diabetes mellitus.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:12

    Topics: Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Risk Factors; Vitamin B 12

2003
Evidence suggests diabetes outcomes linked to homocysteine.
    Nephrology news & issues, 2003, Volume: 17, Issue:13

    Topics: Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex

2003
[Relationship between methylenetetrahydrofolate reductase gene polymorphism and homocysteine in type 1 diabetic microvascular complications].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Female; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Regression Analysis

2003
Increments in circulating homocysteine before and after coronary artery bypass surgery in diabetic and non-diabetic patients.
    Hematology (Amsterdam, Netherlands), 2004, Volume: 9, Issue:2

    Topics: Biomarkers; Cardiopulmonary Bypass; Coronary Artery Bypass; Diabetes Mellitus; Diabetic Angiopathies; Homocysteine; Humans; Reference Values

2004
Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises.
    Diabetes, 2004, Volume: 53, Issue:8

    Topics: Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cytokines; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Female; Homocysteine; Humans; Hydrogen-Ion Concentration; Hyperglycemia; Lipid Peroxidation; Male; Middle Aged; Obesity; Oxidative Stress; Plasminogen Activator Inhibitor 1; Reference Values

2004
Study of total homocyst(e)ine levels in type 2 diabetic patients with silent brain infarction.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2003, Volume: 41, Issue:4

    Topics: Cerebral Infarction; Cerebral Ventricles; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Homocysteine; Humans; Lipid Peroxidation; Male; Middle Aged; Prospective Studies; Reactive Oxygen Species

2003
Homocysteine concentrations and vascular complications in patients with type 2 diabetes.
    Diabetes & metabolism, 2005, Volume: 31, Issue:2

    Topics: Age of Onset; Aged; Biomarkers; Blood Pressure; Body Mass Index; Body Size; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Reference Values; Risk Factors

2005
Plasma homocysteine and microvascular and macrovascular complications in type 1 diabetes: a cross-sectional nested case-control study.
    Journal of internal medicine, 2005, Volume: 258, Issue:5

    Topics: Adult; Albuminuria; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Retinopathy; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hypertension; Male; Microcirculation; Prospective Studies; Risk Factors

2005
[Homocysteinaemia and degenerative complications in non insulin dependent diabetes mellitus].
    La Tunisie medicale, 2005, Volume: 83, Issue:9

    Topics: Cardiovascular Diseases; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Homocysteine; Humans; Male

2005
Patterns of homocysteine in Kenyans with type 2 diabetes without overt cardiovascular disease at Kenyatta National Hospital, Nairobi.
    East African medical journal, 2005, Volume: 82, Issue:12 Suppl

    Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Homocysteine; Humans; Kenya; Male; Middle Aged; Outpatient Clinics, Hospital; Prospective Studies; Risk Assessment; Risk Factors; Time Factors

2005
Risk factors for progression of peripheral arterial disease in large and small vessels.
    Circulation, 2006, Jun-06, Volume: 113, Issue:22

    Topics: Aged; Ankle; Brachial Artery; C-Reactive Protein; Cholesterol, HDL; Diabetes Mellitus; Diabetic Angiopathies; Disease Progression; Female; Homocysteine; Humans; Inflammation; Lipoprotein(a); Longitudinal Studies; Male; Middle Aged; Multivariate Analysis; Peripheral Vascular Diseases; Predictive Value of Tests; Regression Analysis; Risk Factors; Serum Amyloid A Protein; Smoking; Toes

2006
Methylenetetrahydrofolate reductase gene polymorphism, homocysteine and risk of macroangiopathy in Type 2 diabetes mellitus.
    Journal of endocrinological investigation, 2006, Volume: 29, Issue:9

    Topics: Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Regression Analysis

2006
Plasma homocysteine, oxidative stress and endothelial function in patients with Type 1 diabetes mellitus and microalbuminuria.
    Diabetic medicine : a journal of the British Diabetic Association, 2006, Volume: 23, Issue:12

    Topics: Adult; Albuminuria; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Endothelium, Vascular; Female; Homocysteine; Humans; Male; Oxidative Stress

2006
Differences in expression of cardiovascular risk factors among type 2 diabetes mellitus patients of different age.
    Annals of the New York Academy of Sciences, 2006, Volume: 1084

    Topics: Adolescent; Adult; Aging; Biomarkers; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Homocysteine; Humans; Male; Reference Values; Risk Factors; Triglycerides

2006
Progressive glycosylation of albumin and its effect on the binding of homocysteine may be a key step in the pathogenesis of vascular damage in diabetes mellitus.
    Medical hypotheses, 2007, Volume: 69, Issue:1

    Topics: Albumins; Blood Vessels; Diabetic Angiopathies; Glycosylation; Homocysteine; Humans; Models, Cardiovascular; Signal Transduction

2007
Association of serum resistin with TNF system activity in Japanese type 2 diabetic patients.
    Diabetes & metabolism, 2007, Volume: 33, Issue:2

    Topics: Albuminuria; Atherosclerosis; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Homocysteine; Humans; Japan; Resistin; Tumor Necrosis Factor-alpha

2007
Circulating homocysteine and large arterial stiffness and thickness in a population-based sample of middle-aged and elderly men.
    Journal of human hypertension, 2007, Volume: 21, Issue:12

    Topics: Aged; Arterial Occlusive Diseases; Biomarkers; Blood Pressure; Carotid Arteries; Cohort Studies; Diabetic Angiopathies; Homocysteine; Humans; Male; Middle Aged; Netherlands; Pulse; Tunica Intima; Tunica Media

2007
Plasma homocysteine concentrations in Japanese patients with non-insulin-dependent diabetes mellitus: effect of parenteral methylcobalamin treatment.
    Atherosclerosis, 1993, Volume: 103, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Homocysteine; Humans; Injections, Intramuscular; Male; Middle Aged; Risk Factors; Vitamin B 12

1993
Hyperhomocysteinemia following a methionine load in patients with non-insulin-dependent diabetes mellitus and macrovascular disease.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:1

    Topics: Administration, Oral; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Homocysteine; Humans; Male; Methionine; Middle Aged; Time Factors

1996
Oxidative stress in diabetic macrovascular disease: does homocysteine play a role?
    Southern medical journal, 1997, Volume: 90, Issue:9

    Topics: Adult; Analysis of Variance; Brain Ischemia; Carotid Artery Diseases; Case-Control Studies; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Free Radicals; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Male; Methionine; Middle Aged; Oxidative Stress; Peripheral Vascular Diseases; Sulfonylurea Compounds; Thiobarbiturates

1997
Elevated plasma homocysteine and diabetic vascular disease.
    Diabetes care, 1997, Volume: 20, Issue:12

    Topics: Diabetes Mellitus, Type 1; Diabetic Angiopathies; Homocysteine; Humans

1997
Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM.
    Diabetes care, 1997, Volume: 20, Issue:12

    Topics: Administration, Oral; Adult; Albuminuria; Case-Control Studies; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Endothelium, Vascular; Female; Homocysteine; Homocystine; Humans; Male; Methionine; Middle Aged; Reference Values; Thrombomodulin

1997
Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM.
    Diabetes care, 1998, Volume: 21, Issue:5

    Topics: Adult; Aged; Albuminuria; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Drug Synergism; Endothelium, Vascular; Fasting; Female; Glycation End Products, Advanced; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Thrombomodulin

1998
Plasma homocysteine is related to albumin excretion rate in patients with diabetes mellitus: a new link between diabetic nephropathy and cardiovascular disease?
    Diabetologia, 1998, Volume: 41, Issue:6

    Topics: Adult; Aged; Albuminuria; Analysis of Variance; Biomarkers; Body Mass Index; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Proteinuria; Regression Analysis; Vitamins

1998
International Diabetes Federation Meeting, 1997, and other recent meetings. Atherosclerosis and related topics.
    Diabetes care, 1998, Volume: 21, Issue:8

    Topics: Antioxidants; Arteriosclerosis; Coronary Disease; Diabetes Mellitus; Diabetic Angiopathies; Homocysteine; Humans; Risk Factors

1998
Fasting and post-methionine load homocyst(e)ine values are correlated with microalbuminuria and could contribute to worsening vascular damage in non-insulin-dependent diabetes mellitus patients.
    Metabolism: clinical and experimental, 1998, Volume: 47, Issue:8

    Topics: Aged; Albuminuria; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fasting; Female; Homocysteine; Humans; Male; Methionine; Middle Aged

1998
Plasma homocysteine concentrations in patients with type 1 diabetes.
    Diabetes care, 1998, Volume: 21, Issue:11

    Topics: Adult; Cohort Studies; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Male; Microcirculation

1998
Is plasma homocysteine related to albumin excretion rate in patients with diabetes mellitus?
    Diabetologia, 1999, Volume: 42, Issue:3

    Topics: Albuminuria; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Homocysteine; Humans

1999
Enhanced platelet aggregation, high homocysteine level, and microvascular disease in diabetic muscle infarctions: implications for therapy.
    Endocrine, 1999, Volume: 11, Issue:1

    Topics: Adult; Aspirin; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Female; Folic Acid; Hematinics; Homocysteine; Humans; Infarction; Magnetic Resonance Imaging; Microvascular Angina; Muscular Diseases; Platelet Aggregation; Platelet Aggregation Inhibitors; Regional Blood Flow

1999
The significance of serum homocysteine levels in diabetic patients on haemodialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:6

    Topics: Aged; Arteriosclerosis; Biomarkers; Creatinine; Diabetic Angiopathies; Diabetic Nephropathies; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Risk Factors; Serum Albumin

2000
Factors influencing plasma homocysteine levels in type 2 diabetes.
    Diabetes care, 2000, Volume: 23, Issue:3

    Topics: Albuminuria; Blood Pressure; Cholesterol; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Homocysteine; Humans; Male; Reference Values; Regression Analysis; Triglycerides; Vitamins

2000
Hyperhomocysteinemia in type 2 diabetes: relationship to macroangiopathy, nephropathy, and insulin resistance.
    Diabetes care, 2000, Volume: 23, Issue:12

    Topics: Aged; Cohort Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Logistic Models; Male; Metabolic Clearance Rate; Metformin; Middle Aged; Vitamin B 12

2000
Plasma homocysteine and microvascular complications in type 1 diabetes.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2000, Volume: 10, Issue:6

    Topics: Adult; Albuminuria; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Vitamin B 12

2000
Plasma homocysteine, methylenetetrahydrofolate reductase gene polymorphism and carotid intima-media thickness in Italian type 2 diabetic patients.
    European journal of clinical investigation, 2002, Volume: 32, Issue:1

    Topics: Aged; Carotid Arteries; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Genotype; Homocysteine; Humans; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Single Nucleotide; Prevalence; Risk Factors; Tunica Intima; Ultrasonography

2002
Micro- and macrovascular complications and hyperhomocysteinaemia in type 1 diabetic patients.
    Diabetes & metabolism, 2001, Volume: 27, Issue:6

    Topics: Adult; Aging; Blood Pressure; Cholesterol; Cholesterol, HDL; Creatinine; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Retinopathy; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Time Factors

2001
Serum homocysteine concentration is related to diabetes mellitus, but not to coronary heart disease, in Saudi Arabians.
    Diabetes, obesity & metabolism, 2002, Volume: 4, Issue:2

    Topics: Adolescent; Adult; Arteriosclerosis; Biomarkers; Body Mass Index; Child; Cholesterol; Chromatography, High Pressure Liquid; Coronary Disease; Diabetes Mellitus; Diabetic Angiopathies; Female; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Saudi Arabia; Triglycerides

2002
Homocysteine, folate, methylene tetrahydrofolate reductase genotype and vascular morbidity in diabetic subjects.
    Clinical science (London, England : 1979), 2002, Volume: 102, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Coronary Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Stroke

2002