homocysteine and Depressive Disorder

homocysteine has been researched along with Depressive Disorder in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's3 (10.34)18.2507
2000's16 (55.17)29.6817
2010's6 (20.69)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Esnafoglu, E; Ozturan, DD1
Armin, M; Askari, G; Clark, CCT; Lotfi, K; Moradi, F; Rouhani, MH1
Ďuračková, Z; Garaiova, I; Katrenčíková, B; Laubertová, L; Nagyová, Z; Paduchová, Z; Trebatická, J; Vaváková, M1
Benaková, H; Fisar, Z; Hroudová, J; Jirák, R; Kitzlerová, E; Raboch, J; Zvĕrová, M1
Almeida, OP; Flicker, L; Hankey, GJ; Jamrozik, K; McCaul, K; Norman, P1
Hallert, C; Hultberg, B; Svensson, M; Tholstrup, J1
Benyamina, A; Blecha, L; Debuire, B; Karila, L; Lemoine, A; Pham, P; Reynaud, M; Saffroy, R1
Graber, JJ; Kaufmann, H; Kolodny, EH; Sathe, S; Sherman, FT1
Chin, AV; Coen, R; Cunningham, CJ; Hamilton, F; Lawlor, BA; Molloy, AM; O'Connell, H; O'Luanaigh, C; Robinson, DJ; Scott, J; Tehee, E1
Ebesunun, MO; Eruvulobi, HU; Olagunju, T; Owoeye, OA1
Cardinal, BJ; Loprinzi, PD1
Alfonso, H; Almeida, OP; Flicker, L; Hankey, GJ; McCaul, K; Yeap, BB1
Mattson, MP; Shea, TB1
Bjelland, I; Refsum, H; Tell, GS; Ueland, PM; Vollset, SE1
Alpert, JE; Bottiglieri, T; Fava, M; Mischoulon, D; Nierenberg, AA; Papakostas, GI; Petersen, T; Rosenbaum, JF; Ryan, JL1
Alpert, JE; Bottiglieri, T; Fava, M; Green, CH; Mischoulon, D; Nierenberg, AA; Papakostas, GI; Petersen, T; Rosenbaum, JF1
Kelly, CB; McDonnell, AP; Paul, RT1
Christensen, H; Jorm, AF; Lux, O; Naidoo, D; Parslow, RA; Sachdev, PS; Salonikas, C; Wen, W1
Gustafson, L; Hultberg, B; Nilsson, K2
Arsenault, L; Buel, J; Buell, J; Folstein, M; Liu, T; Peter, I; Qiu, WW; Scott, T1
Bleich, S; Frieling, H; Hillemacher, T; Muschler, MA1
Bedson, E; Hughes, D; Lloyd, K; Menkes, DB; Moat, S; Pirmohamed, M; Roberts, SH; Russell, I; Slegg, G; Thome, J; Tranter, R; Whitaker, R; Wilkinson, C1
Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yang, SJ; Yoon, JS1
Alpert, JE; Borus, JS; Bottiglieri, T; Fava, M; Nierenberg, AA; Rosenbaum, JF1
Bottiglieri, T1
Fuchs, D; Leblhuber, F; Sperner-Unterweger, B; Widner, B1
Bell, IR; Cole, JO; Edman, JS; Kayne, HL; Marby, DW; Morrow, FD; Selhub, J1
Bartlett, JR; Bowen, DM; Bridges, PK; Bruton, CJ; Francis, PT; Lowe, SL; Najlerahim, A; Poynton, A; Procter, AW1

Reviews

6 review(s) available for homocysteine and Depressive Disorder

ArticleYear
The association between serum homocysteine and depression: A systematic review and meta-analysis of observational studies.
    European journal of clinical investigation, 2021, Volume: 51, Issue:5

    Topics: Depression; Depressive Disorder; Homocysteine; Humans; Hyperhomocysteinemia; Observational Studies as Topic; Risk Factors

2021
Homocysteine and depression in later life.
    Archives of general psychiatry, 2008, Volume: 65, Issue:11

    Topics: Age Factors; Aged; Cohort Studies; Depressive Disorder; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Personality Inventory; Polymorphism, Genetic; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12

2008
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
    Trends in neurosciences, 2003, Volume: 26, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke

2003
Folic acid: neurochemistry, metabolism and relationship to depression.
    Human psychopharmacology, 2004, Volume: 19, Issue:7

    Topics: Brain; Depressive Disorder; Dietary Supplements; Folic Acid; Homocysteine; Humans

2004
The homocysteine hypothesis of depression.
    The American journal of psychiatry, 2007, Volume: 164, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Child; Comorbidity; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mutation; Neurotransmitter Agents; Stroke; Vitamin B 12; Vitamin B 6

2007
Folate, vitamin B12, and neuropsychiatric disorders.
    Nutrition reviews, 1996, Volume: 54, Issue:12

    Topics: Depressive Disorder; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylation; Multiple Sclerosis; Vitamin B 12; Vitamin B 12 Deficiency

1996

Trials

6 trial(s) available for homocysteine and Depressive Disorder

ArticleYear
The Effect of Omega-3 Fatty Acids on Thromboxane, Brain-Derived Neurotrophic Factor, Homocysteine, and Vitamin D in Depressive Children and Adolescents: Randomized Controlled Trial.
    Nutrients, 2021, Mar-27, Volume: 13, Issue:4

    Topics: Adolescent; Brain-Derived Neurotrophic Factor; Case-Control Studies; Child; Depressive Disorder; Dietary Supplements; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Fish Oils; Homocysteine; Humans; Male; Thromboxanes; Vitamin D

2021
Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet.
    Alimentary pharmacology & therapeutics, 2009, Apr-15, Volume: 29, Issue:8

    Topics: Anxiety; Celiac Disease; Depressive Disorder; Diet, Gluten-Free; Female; Folic Acid; Health Status; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex

2009
Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 1: predictors of clinical response in fluoxetine-resistant depression.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:8

    Topics: Adult; Ambulatory Care; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Lithium; Male; Probability; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Vitamin B 12

2004
Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 2: predictors of relapse during the continuation phase of pharmacotherapy.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:8

    Topics: Adult; Ambulatory Care; Depressive Disorder; Drug Administration Schedule; Female; Fluoxetine; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Probability; Psychiatric Status Rating Scales; Recurrence; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Vitamin B 12

2004
Folate augmentation of treatment - evaluation for depression (FolATED): protocol of a randomised controlled trial.
    BMC psychiatry, 2007, Nov-15, Volume: 7

    Topics: Adult; Antidepressive Agents, Second-Generation; Cohort Studies; Cost-Benefit Analysis; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Family Practice; Female; Fluoxetine; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Psychiatry

2007
Folate, vitamin B12, and homocysteine in major depressive disorder.
    The American journal of psychiatry, 1997, Volume: 154, Issue:3

    Topics: Adolescent; Adult; Ambulatory Care; Depressive Disorder; Female; Fluoxetine; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency

1997

Other Studies

17 other study(ies) available for homocysteine and Depressive Disorder

ArticleYear
The relationship of severity of depression with homocysteine, folate, vitamin B12, and vitamin D levels in children and adolescents.
    Child and adolescent mental health, 2020, Volume: 25, Issue:4

    Topics: Adolescent; Child; Depressive Disorder; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D

2020
Plasma homocysteine in Alzheimer's disease with or without co-morbid depressive symptoms.
    Neuro endocrinology letters, 2014, Volume: 35, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Comorbidity; Depressive Disorder; Female; Homocysteine; Humans; Male; Middle Aged; Severity of Illness Index

2014
Association between MTHFR 677C-T polymorphism and alcohol dependence according to Lesch and Babor typology.
    Addiction biology, 2009, Volume: 14, Issue:4

    Topics: Adult; Alcoholism; Depressive Disorder; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12

2009
Vitamin B12-responsive severe leukoencephalopathy and autonomic dysfunction in a patient with "normal" serum B12 levels.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:12

    Topics: Autoantibodies; Autonomic Nervous System Diseases; Brain; Cognition Disorders; Depressive Disorder; Drug Therapy, Combination; Female; Homocysteine; Humans; Intrinsic Factor; Leukoencephalopathies; Magnetic Resonance Imaging; Mental Status Schedule; Methylmalonic Acid; Middle Aged; Neurologic Examination; Psychometrics; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D

2010
Associations between holotranscobalamin, vitamin B12, homocysteine and depressive symptoms in community-dwelling elders.
    International journal of geriatric psychiatry, 2011, Volume: 26, Issue:3

    Topics: Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Depressive Disorder; Female; Homocysteine; Humans; Male; Northern Ireland; Personal Satisfaction; Prospective Studies; Transcobalamins; Urban Population; Vitamin B 12

2011
Elevated plasma homocysteine in association with decreased vitamin B(12), folate, serotonin, lipids and lipoproteins in depressed patients.
    African journal of psychiatry, 2012, Volume: 15, Issue:1

    Topics: Adult; Cholesterol; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Lipids; Lipoproteins; Male; Middle Aged; Risk Factors; Serotonin; Sex Distribution; Vitamin B 12; Young Adult

2012
Interrelationships among physical activity, depression, homocysteine, and metabolic syndrome with special considerations by sex.
    Preventive medicine, 2012, Volume: 54, Issue:6

    Topics: Acceleration; Adult; Aged; Aged, 80 and over; Blood Pressure; Body Mass Index; Confidence Intervals; Depressive Disorder; Exercise; Female; Health Knowledge, Attitudes, Practice; Homocysteine; Humans; Life Style; Male; Metabolic Syndrome; Middle Aged; Nutrition Surveys; Severity of Illness Index; Sex Factors; Surveys and Questionnaires; United States

2012
Aspirin decreases the risk of depression in older men with high plasma homocysteine.
    Translational psychiatry, 2012, Aug-14, Volume: 2

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Aspirin; Australia; Cross-Sectional Studies; Depression; Depressive Disorder; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Platelet Aggregation Inhibitors; Risk; Vitamin B Complex

2012
Folate, vitamin B12, homocysteine, and the MTHFR 677C->T polymorphism in anxiety and depression: the Hordaland Homocysteine Study.
    Archives of general psychiatry, 2003, Volume: 60, Issue:6

    Topics: Aged; Anxiety Disorders; Cohort Studies; Cross-Sectional Studies; Depressive Disorder; Folic Acid; Genotype; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Norway; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Personality Inventory; Polymorphism, Genetic; Risk Factors; Vitamin B 12

2003
Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample.
    Psychological medicine, 2005, Volume: 35, Issue:4

    Topics: Aged; Antioxidants; Australia; Brain; Case-Control Studies; Causality; Creatinine; Cross-Sectional Studies; Depressive Disorder; Depressive Disorder, Major; Female; Folic Acid; Folic Acid Deficiency; Health Status Indicators; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Personality Assessment; Predictive Value of Tests; Psychometrics; Reference Values; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency

2005
Plasma homocysteine and vascular disease in psychogeriatric patients.
    Dementia and geriatric cognitive disorders, 2006, Volume: 21, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Confusion; Dementia; Dementia, Vascular; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Middle Aged; Natriuretic Peptide, Brain; Neuropsychological Tests; Peptide Fragments; Reference Values; Risk Factors; Vitamin B 12

2006
Plasma homocysteine, cobalamin/folate status, and vascular disease in a large population of psychogeriatric patients.
    Dementia and geriatric cognitive disorders, 2006, Volume: 22, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Depressive Disorder; Female; Folic Acid; Hematocrit; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Nutritional Status; Population; Sweden; Vascular Diseases; Vitamin B 12

2006
Homocysteine and epigenetic DNA methylation: a biological model for depression?
    The American journal of psychiatry, 2007, Volume: 164, Issue:10

    Topics: Depressive Disorder; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological

2007
Predictive value of folate, vitamin B12 and homocysteine levels in late-life depression.
    The British journal of psychiatry : the journal of mental science, 2008, Volume: 192, Issue:4

    Topics: Aged; Cross-Sectional Studies; Depressive Disorder; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Male; Predictive Value of Tests; Vitamin B 12 Deficiency; Vitamin B Complex

2008
Does disturbed homocysteine and folate metabolism in depression result from enhanced oxidative stress?
    Journal of neurology, neurosurgery, and psychiatry, 2001, Volume: 70, Issue:3

    Topics: Depressive Disorder; Folic Acid; Homocysteine; Humans; Oxidative Stress

2001
Plasma homocysteine in vascular disease and in nonvascular dementia of depressed elderly people.
    Acta psychiatrica Scandinavica, 1992, Volume: 86, Issue:5

    Topics: Adult; Age Factors; Aged; Cognition Disorders; Cross-Sectional Studies; Dementia; Depressive Disorder; Female; Homocysteine; Humans; Male; Vascular Diseases

1992
Brain amino acid concentrations and Ca2+-dependent release in intractable depression assessed antemortem.
    Brain research, 1989, Aug-14, Volume: 494, Issue:2

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Calcium; Depressive Disorder; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homocysteine; Humans; Male; Middle Aged

1989