homocysteine and Depression, Involutional

homocysteine has been researched along with Depression, Involutional in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (53.13)29.6817
2010's13 (40.63)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Amini, M; Hosseinzadeh, M; Khosravi, M; Mansoori, A; Raisi, F; Sotoudeh, G1
Pu, M; Sun, X; Xu, Z; Yuan, B; Yuan, Y; Zhang, Z1
Bleich, S; Frieling, H; Helm, S; Hillemacher, T; Jakubovski, E; Kahl, KG; Maier, H; Moschny, N; Neyazi, A; Sperling, W; Toto, S1
Fu, Z; Tao, R; Xiao, L1
Bochud, M; Glaus, J; Lasserre, AM; Nabi, H; Preisig, M; Vollenweider, P; Waeber, G1
Almeida, OP; Flicker, L; Ford, AH; Hirani, V; Singh, U1
Delport, D; Fisher, LR; Geiger, D; Kotze, MJ; Schoeman, R; van der Merwe, L; van der Merwe, N1
Assies, J; Bockting, CL; de Vries, GJ; Derks, EM; Kayser, M; Koeter, MW; Lok, A; Mocking, RJ; Schene, AH; Visser, I1
Assies, J; Bockting, CL; Koeter, MW; Lok, A; Mocking, RJ; Pouwer, F; Ruhé, HG; Schene, AH; Visser, I1
Farah, A; Mech, AW1
Apitz, R; Campos, J; García, A; Lavie, R; Lima, L; Mata, S; Resler, G; Urbina, M1
Chellappa, P; Ramaraj, R1
Chen, CS; Chou, MC; Lai, CL; Liao, YC; Liu, CK; Yang, YH; Yeh, YC; Yen, CF1
Aydogan, S; Ozüm, Ü; Yapislar, H1
Alpert, JE; Arning, E; Bottiglieri, T; Fava, M; Mischoulon, D; Papakostas, GI1
Alpert, JE; Baer, L; Clain, AJ; Dording, CM; Farabaugh, AH; Fava, M; Iosifescu, DV; Katz, J; Lamon-Fava, S; Mischoulon, D; Nierenberg, AA; Papakostas, GI; Selhub, J; Yeung, AS1
Kornhuber, J; Kreil, S; Maler, JM; Müller, H; Rotter-Neubert, A; Sperling, W1
Hickie, I; Little, C; Mitchell, P; Naismith, S; Parker, G; Scott, E; Turner, K; Ward, PB; Wilhelm, K1
d'Almeida, V; de Souza, FG; Nobrega, JN; Setnik, B1
Bolander-Gouaille, C; Coppen, A1
Hickie, I; Mitchell, P; Naismith, S; Parker, G; Scott, E; Ward, PB; Wilhelm, K1
Christensen, H; Jorm, AF; Lux, O; Naidoo, D; Parslow, RA; Sachdev, PS; Salonikas, C; Wen, W1
Alpert, JE; Bottiglieri, T; Fava, M; Lebowitz, BD; Mischoulon, D; Nierenberg, AA; Papakostas, GI; Petersen, T; Rosenbaum, JF; Ryan, JL1
Chen, CS; Chiang, IC; Devanand, DP; Kuo, YT; Lin, HF; Tsai, JC; Tsang, HY1
Alpert, JE; Fava, M; Iosifescu, DV; Lee, HK; Lyoo, IK; Nierenberg, AA; Papakostas, GI; Renshaw, PF1
Alpert, JE; Fava, M; Iosifescu, DV; Lee, HK; Lyoo, IK; Nierenberg, A; Papakostas, GI; Renshaw, PF1
Alpert, J; Bottiglieri, T; Fava, M; Fraguas, R; Mischoulon, D; Papakostas, GI1
Dirican, M; Eker, SS; Hizli, BZ; Karaagac, EU; Kirli, S; Sarandol, A; Sarandol, E1
Almeida, OP; Flicker, L; Hankey, GJ; Jamrozik, K; Norman, P; van Bockxmeer, FM; Vasikaran, S1
Chengappa, KN; Levine, J1
Morris, DW; Rush, AJ; Trivedi, MH1
Bailey, J; Coppen, A1

Reviews

2 review(s) available for homocysteine and Depression, Involutional

ArticleYear
Treatment of depression: time to consider folic acid and vitamin B12.
    Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:1

    Topics: Brain; Depressive Disorder, Major; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency

2005
Folate and unipolar depression.
    Journal of alternative and complementary medicine (New York, N.Y.), 2008, Volume: 14, Issue:3

    Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder, Major; Drug Therapy, Combination; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Treatment Outcome

2008

Trials

7 trial(s) available for homocysteine and Depression, Involutional

ArticleYear
The one-carbon-cycle and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in recurrent major depressive disorder; influence of antidepressant use and depressive state?
    Journal of affective disorders, 2014, Volume: 166

    Topics: Adult; Antidepressive Agents; Carbon; Case-Control Studies; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Recurrence; Vitamin B 12; Vitamin B 6

2014
Correlation of clinical response with homocysteine reduction during therapy with reduced B vitamins in patients with MDD who are positive for MTHFR C677T or A1298C polymorphism: a randomized, double-blind, placebo-controlled study.
    The Journal of clinical psychiatry, 2016, Volume: 77, Issue:5

    Topics: Adolescent; Adult; Depressive Disorder, Major; Double-Blind Method; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Middle Aged; Polymorphism, Genetic; Psychiatric Status Rating Scales; Statistics as Topic; Vitamin B Complex; Young Adult

2016
Effect of folic acid combined with fluoxetine in patients with major depression on plasma homocysteine and vitamin B12, and serotonin levels in lymphocytes.
    Neuroimmunomodulation, 2008, Volume: 15, Issue:3

    Topics: Adult; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Down-Regulation; Drug Synergism; Drug Therapy, Combination; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Lymphocytes; Male; Middle Aged; Neuropsychological Tests; Selective Serotonin Reuptake Inhibitors; Serotonin; Severity of Illness Index; Treatment Outcome; Vitamin B 12; Vitamin B Complex; Young Adult

2008
Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:6

    Topics: Biological Availability; Depressive Disorder, Major; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Psychiatric Status Rating Scales; S-Adenosylhomocysteine; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates

2012
The relationship between serum folate, vitamin B12, and homocysteine levels in major depressive disorder and the timing of improvement with fluoxetine.
    The international journal of neuropsychopharmacology, 2005, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Vitamin B 12

2005
Oxidation of apolipoprotein B-containing lipoproteins and serum paraoxonase/arylesterase activities in major depressive disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Aug-30, Volume: 30, Issue:6

    Topics: Adult; Antidepressive Agents; Apolipoproteins B; Aryldialkylphosphatase; C-Reactive Protein; Carboxylic Ester Hydrolases; Cholesterol; Cholesterol, HDL; Depressive Disorder, Major; Female; Homocysteine; Humans; Lipoproteins; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Phenotype; Psychiatric Status Rating Scales; Triglycerides

2006
Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial.
    Journal of affective disorders, 2000, Volume: 60, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Sex Factors; Treatment Outcome; Vitamin B 12

2000

Other Studies

23 other study(ies) available for homocysteine and Depression, Involutional

ArticleYear
The relationship between dietary patterns and depression mediated by serum levels of Folate and vitamin B12.
    BMC psychiatry, 2020, 02-13, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Depression; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Iran; Logistic Models; Male; Middle Aged; Tryptophan; Vitamin B 12; Young Adult

2020
Influence of genetic polymorphisms in homocysteine and lipid metabolism systems on antidepressant drug response.
    BMC psychiatry, 2020, 08-14, Volume: 20, Issue:1

    Topics: Antidepressive Agents; Depressive Disorder, Major; Genotype; Homocysteine; Humans; Lipid Metabolism; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide

2020
S100B, Homocysteine, Vitamin B12, Folic Acid, and Procalcitonin Serum Levels in Remitters to Electroconvulsive Therapy: A Pilot Study.
    Disease markers, 2018, Volume: 2018

    Topics: Adult; Aged; Biomarkers; Calcitonin; Depressive Disorder, Major; Electroconvulsive Therapy; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pilot Projects; Remission Induction; S100 Calcium Binding Protein beta Subunit; Severity of Illness Index; Treatment Outcome; Vitamin B 12

2018
Chronic Food Antigen-specific IgG-mediated Hypersensitivity Reaction as A Risk Factor for Adolescent Depressive Disorder.
    Genomics, proteomics & bioinformatics, 2019, Volume: 17, Issue:2

    Topics: Adolescent; Biomarkers; C-Reactive Protein; Chronic Disease; Cytokines; Depressive Disorder, Major; Female; Food Hypersensitivity; Histamine; Homocysteine; Humans; Immunoglobulin E; Immunoglobulin G; Inflammation Mediators; Male; Risk Factors; S100 Calcium Binding Protein beta Subunit; Young Adult

2019
Association of serum homocysteine with major depressive disorder: results from a large population-based study.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:10

    Topics: Adult; Aged; Depressive Disorder, Major; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Factors; Socioeconomic Factors; Switzerland

2013
Homocysteine, depression and cognitive function in older adults.
    Journal of affective disorders, 2013, Volume: 151, Issue:2

    Topics: Aged; Cognition Disorders; Cross-Sectional Studies; Depressive Disorder, Major; Female; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic

2013
Significance of dietary folate intake, homocysteine levels and MTHFR 677 C>T genotyping in South African patients diagnosed with depression: test development for clinical application.
    Metabolic brain disease, 2014, Volume: 29, Issue:2

    Topics: Adult; Biomarkers; Depressive Disorder, Major; Diet; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; South Africa; Surveys and Questionnaires

2014
Erythrocyte fatty acid profiles and plasma homocysteine, folate and vitamin B6 and B12 in recurrent depression: Implications for co-morbidity with cardiovascular disease.
    Psychiatry research, 2015, Oct-30, Volume: 229, Issue:3

    Topics: Adult; Cardiovascular Diseases; Comorbidity; Depressive Disorder, Major; Erythrocytes; Fatty Acids; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Oxidative Stress; Recurrence; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2015
Depression, homocysteine concentration, and cardiovascular events.
    JAMA, 2009, Apr-15, Volume: 301, Issue:15

    Topics: Biomarkers; Coronary Disease; Depression; Depressive Disorder, Major; Homocysteine; Humans; Risk Factors

2009
Plasma homocysteine levels and major depressive disorders in Alzheimer disease.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010, Volume: 18, Issue:11

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Depressive Disorder, Major; Female; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Severity of Illness Index

2010
Biological understanding of the cardiovascular risk associated with major depression and panic disorder is important.
    International journal of psychiatry in clinical practice, 2012, Volume: 16, Issue:1

    Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Endothelium, Vascular; Female; Homocysteine; Humans; Male; Nitric Oxide; Nitrites; Panic Disorder; Platelet Aggregation; Risk Factors; Spectrophotometry

2012
Prevalence of MTHFR C677T and MS A2756G polymorphisms in major depressive disorder, and their impact on response to fluoxetine treatment.
    CNS spectrums, 2012, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Prevalence; Psychiatric Status Rating Scales; Statistics, Nonparametric; Vitamin B 12; Young Adult

2012
Correlation between homocysteine serum levels and the duration of seizures in patients treated with electroconvulsive therapy.
    The journal of ECT, 2012, Volume: 28, Issue:3

    Topics: Depressive Disorder, Major; Electroconvulsive Therapy; Electroencephalography; Female; Homocysteine; Humans; Male; Prospective Studies; Seizures; Vitamins

2012
Caudate nucleus volumes and genetic determinants of homocysteine metabolism in the prediction of psychomotor speed in older persons with depression.
    The American journal of psychiatry, 2002, Volume: 159, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Apolipoproteins E; Caudate Nucleus; Depressive Disorder, Major; Female; Genotype; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neuropsychological Tests; Oxidoreductases Acting on CH-NH Group Donors; Psychomotor Disorders

2002
Increased homocysteine levels associated with sex and stress in the learned helplessness model of depression.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:1

    Topics: Animals; Depressive Disorder, Major; Escape Reaction; Female; Helplessness, Learned; Homocysteine; Male; Rats; Rats, Sprague-Dawley; Sex Characteristics; Stress, Physiological

2004
Vascular risk and low serum B12 predict white matter lesions in patients with major depression.
    Journal of affective disorders, 2005, Volume: 85, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Brain; Cerebral Cortex; Cerebral Ventricles; Cohort Studies; Comorbidity; Depressive Disorder, Major; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hypertension; Hypertensive Encephalopathy; Intracranial Arteriosclerosis; Magnetic Resonance Imaging; Male; Middle Aged; Reference Values; Risk Factors; Statistics as Topic; Vitamin B 12 Deficiency

2005
Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample.
    Psychological medicine, 2005, Volume: 35, Issue:4

    Topics: Aged; Antioxidants; Australia; Brain; Case-Control Studies; Causality; Creatinine; Cross-Sectional Studies; Depressive Disorder; Depressive Disorder, Major; Female; Folic Acid; Folic Acid Deficiency; Health Status Indicators; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Personality Assessment; Predictive Value of Tests; Psychometrics; Reference Values; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency

2005
Homocysteine levels, MTHFR C677T genotype, and MRI Hyperintensities in late-onset major depressive disorder.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:10

    Topics: Age of Onset; Aged; Brain; Depressive Disorder, Major; DNA Primers; Female; Gene Expression; Genotype; Homocysteine; Humans; Leukocytes; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction

2005
Brain MRI white matter hyperintensities and one-carbon cycle metabolism in non-geriatric outpatients with major depressive disorder (Part II).
    Psychiatry research, 2005, Dec-30, Volume: 140, Issue:3

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Brain; Demography; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Vitamin B 12

2005
Brain MRI white matter hyperintensities and one-carbon cycle metabolism in non-geriatric outpatients with major depressive disorder (Part I).
    Psychiatry research, 2005, Dec-30, Volume: 140, Issue:3

    Topics: Adolescent; Adult; Aged; Brain; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Severity of Illness Index; Vitamin B 12

2005
Anger attacks in major depressive disorder and serum levels of homocysteine.
    Biological psychiatry, 2006, Aug-01, Volume: 60, Issue:3

    Topics: Adult; Age Factors; Aged; Alcohol Drinking; Anger; Creatinine; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Severity of Illness Index; Smoking; Surveys and Questionnaires; Time Factors; Vitamin B 12

2006
Association of cardiovascular risk factors and disease with depression in later life.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2007, Volume: 15, Issue:6

    Topics: Age of Onset; Aged; Aged, 80 and over; Angina Pectoris; Cardiovascular Diseases; Cross-Sectional Studies; Depressive Disorder, Major; Diabetes Mellitus, Type 2; Homocysteine; Humans; Male; Myocardial Infarction; Risk Factors; Stroke; Surveys and Questionnaires; Triglycerides

2007
Exposure to nitrous oxide may be associated with high homocysteine plasma levels and a risk for clinical depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Anesthetics, Inhalation; Dentists, Women; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Female; Homocysteine; Humans; Nitrous Oxide; Occupational Exposure; Risk Assessment

2007