homocysteine has been researched along with Degenerative Diseases, Central Nervous System in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 27 (54.00) | 29.6817 |
| 2010's | 17 (34.00) | 24.3611 |
| 2020's | 6 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boudreault, PL; Comeau, C; Firdaus, SB; Klarskov, K; Komba, JE; Loubane, G; Naylor, S; Robert, G; Venne, P; Wagner, JR | 1 |
| Azzini, E; Polito, A; Ruggeri, S | 1 |
| Liu, B; Pi, T; Shi, J | 1 |
| Chen, Y; Feng, X; Shi, J; Wang, D; Weng, H; Yan, Y; Yin, Y | 1 |
| McCully, KS | 1 |
| Bobermin, LD; Dos Santos, TM; Quincozes-Santos, A; Wyse, ATS | 1 |
| Barrero, C; Li, JG; Merali, S; Praticò, D | 1 |
| Padovani, D | 1 |
| Elahdadi Salmani, M; Goudarzi, I; Koohpeyma, H; Lashkarbolouki, T; Shabani, M | 1 |
| Dodurga, Y; Gundogdu, G; Kucukatay, V | 1 |
| Ludwichowska, A; Szabat, K; Szadejko, K; Sławek, J | 1 |
| Dobrota, D; Drgova, A; Kovalska, M; Lehotsky, J; Mokra, D; Petras, M; Tatarkova, Z | 1 |
| Jakubowski, H; Luczak, M; Marczak, L; Suszyńska-Zajczyk, J | 1 |
| Rabinovitz, S; Yehuda, S | 1 |
| Sharma, M; Tiwari, M; Tiwari, RK | 1 |
| Dar, TA; Kumar, T; Sharma, GS; Singh, LR | 1 |
| Refsum, H; Smith, AD | 1 |
| Andriamihaja, M; Artaud, I; Blachier, F; Castillo, FT; Galardon, E; Hessani, A; Lan, A; Liot, G; Padovani, D; Pilati, C; Sen, S | 1 |
| Blom, HJ; Dijkstra, CD; Killestein, J; Kragt, JJ; Polman, CH; Teunissen, CE | 1 |
| Carrasco, M; Castro, C; Estrada, C; López-Toledano, MA; Murillo-Carretero, M; Rabaneda, LG; Ruiz, FA | 1 |
| Lucassen, PJ; Marlatt, MW; Perry, G; Smith, MA; Zhu, X | 1 |
| Agnati, LF; Fuxe, K; Genedani, S; Guidolin, D; Leo, G; Piron, L; Rivera, A | 1 |
| Colla, M; Endres, M; Kronenberg, G | 1 |
| Boldyrev, AA | 1 |
| Butterfield, DA; Calabrese, V; Cornelius, C; Lentile, R; Mancuso, C; Stella, AM | 1 |
| Davis, J; Leslie, R; Livingstone, C; Newton, LA; Sandhu, K | 1 |
| Herrmann, W; Obeid, R | 2 |
| Borowczyk, K; Jakubowski, H; Tisończyk, J | 1 |
| Ben Abdallah, J; Charfeddine, B; Letaef, A; Limem, K; Naffeti, S; Othmen, LB; Smach, MA | 1 |
| Mattson, MP; Shea, TB | 1 |
| Mattson, MP | 1 |
| Haberman, F; Mattson, MP | 1 |
| Fukuda, Y; Kuroda, Y; Nagaishi, A; Takashima, H | 1 |
| Agarwal, N; Ganapathy, V; Martin, PM; Ola, MS; Smith, SB | 1 |
| Ashline, D; Milhalik, S; Ortiz, D; Rogers, E; Shea, TB | 1 |
| Lominadze, D; Roberts, AM; Tyagi, SC | 1 |
| Doherty, GH; Foister, NS; Mackie, JB; Oldreive, CE | 1 |
| Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M | 1 |
| McCaddon, A; Regland, B | 1 |
| Evert, BO; Jakobs, C; Jarre, E; Klockgether, T; Kunz, WS; Linnebank, M; Lutz, H; Noelker, C; Struys, E; Vielhaber, S; Wüllner, U | 1 |
| Herrmann, M; Herrmann, W; Obeid, R | 1 |
| Doherty, GH | 1 |
| Berry, MJ; Harney, JW; Khrapko, K; Liu, W; Morozova, N; Panee, J | 1 |
| Agnati, LF; Andreoli, N; Arhem, P; Forni, A; Fuxe, K; Genedani, S; Guidolin, D; Leo, G | 1 |
| Brennan, L; Jin, Y | 1 |
| Hasić, S; Jadrić, R; Kiseljaković, E; Resić, H; Skenderi, F; Winterhalter-Jadrić, M | 1 |
| Diaz-Arrastia, R | 1 |
| Jack, CR; Toole, JF | 1 |
| Duan, W; Kruman, II; Mattson, MP | 1 |
25 review(s) available for homocysteine and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Homocysteine: Its Possible Emerging Role in At-Risk Population Groups.
Topics: Aging; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Cardiovascular Diseases; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Neurodegenerative Diseases; Osteoporosis; Pre-Eclampsia; Pregnancy; Risk Factors | 2020 |
Abnormal Homocysteine Metabolism: An Insight of Alzheimer's Disease from DNA Methylation.
Topics: Aged; Alzheimer Disease; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Neurodegenerative Diseases | 2020 |
Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging.
Topics: Aging; Animals; Arteriosclerosis; Cholesterol; Diterpenes; Homocysteine; Humans; Mitochondria; NAD; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Phosphorylation; Permeability; Squalene; Tocotrienols; Vitamin B 12 | 2020 |
Homocysteine and Gliotoxicity.
Topics: Animals; Astrocytes; Gliosis; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Neuroglia | 2021 |
[Homocysteine and its role in pathogenesis of Parkinson's disease and other neurodegenerative disorders].
Topics: Catechol O-Methyltransferase Inhibitors; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Neurodegenerative Diseases; Parkinson Disease; Vitamin B Complex | 2013 |
Hyperhomocysteinemia as a risk factor for the neuronal system disorders.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Risk Factors | 2014 |
Hyperhomocysteinemia: Impact on Neurodegenerative Diseases.
Topics: Animals; Biomarkers; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nutritional Status; Prognosis; Risk Factors; Vitamin B Deficiency | 2015 |
Protein N-homocysteinylation: From cellular toxicity to neurodegeneration.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Homocysteine; Humans; Neurodegenerative Diseases; Neurons; Prions; Protein Aggregates | 2015 |
Homocysteine, B Vitamins, and Cognitive Impairment.
Topics: Aging; Animals; Biomarkers; Cerebrovascular Circulation; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nootropic Agents; Nutritional Status; Practice Guidelines as Topic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies.
Topics: Alzheimer Disease; Cerebrovascular Disorders; Clinical Trials as Topic; Dementia; Homocysteine; Humans; Neurodegenerative Diseases; Oxidative Stress | 2008 |
Folic acid, neurodegenerative and neuropsychiatric disease.
Topics: Aging; Alzheimer Disease; Animals; Brain; Clinical Trials as Topic; Dementia, Vascular; Depression; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Molecular Structure; Neurodegenerative Diseases; Neuronal Plasticity; Stroke; Vitamin B Complex | 2009 |
Molecular mechanisms of homocysteine toxicity.
Topics: Animals; Apoptosis; Blood Cells; Cardiovascular Diseases; Carnosine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neurodegenerative Diseases; Neurons; Pregnancy; Receptors, N-Methyl-D-Aspartate; Risk Factors | 2009 |
Clinical diagnostics for homocysteine: a rogue amino acid?
Topics: Animals; Avitaminosis; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Mental Disorders; Molecular Structure; Neurodegenerative Diseases; Oxidation-Reduction; Pathology, Molecular; Pregnancy; Pregnancy Complications | 2010 |
[Homocysteine, vitamin B-12, folic acid and the cognitive decline in the elderly].
Topics: Aged; Brain; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nutritional Physiological Phenomena; Receptors, N-Methyl-D-Aspartate; Risk Factors; Vitamin B 12 | 2013 |
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke | 2003 |
Methylation and acetylation in nervous system development and neurodegenerative disorders.
Topics: Acetylation; Animals; Diet; DNA; DNA Damage; DNA Methylation; Embryonic and Fetal Development; Folic Acid; Homocysteine; Humans; Nervous System; Neurodegenerative Diseases | 2003 |
Folate and homocysteine metabolism: therapeutic targets in cardiovascular and neurodegenerative disorders.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Models, Biological; Molecular Structure; Neurodegenerative Diseases | 2003 |
Homocysteine in microvascular endothelial cell barrier permeability.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Endothelium, Vascular; Extracellular Matrix; Homocysteine; Humans; Hyperhomocysteinemia; Microcirculation; Models, Cardiovascular; Neurodegenerative Diseases | 2005 |
Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia.
Topics: Aging; Animals; Central Nervous System; Dementia; Homocysteine; Humans; Neurodegenerative Diseases; Rats | 2006 |
Hyperhomocysteinaemia: a critical review of old and new aspects.
Topics: Age Factors; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors; Sex Factors | 2007 |
Homocysteine: more than just a matter of life and death.
Topics: Aging; Animals; Homocysteine; Humans; Neurodegenerative Diseases; Neurotoxins; Risk Factors | 2007 |
Role of cooperativity in protein folding and protein mosaic assemblage relevance for protein conformational diseases.
Topics: Allosteric Regulation; Amyloid beta-Peptides; Homocysteine; Humans; Models, Molecular; Multiprotein Complexes; Neurodegenerative Diseases; Protein Folding; Protein Structure, Quaternary | 2007 |
Polymorphism in methylentetra-hydrofolate reductase gene: important role in diseases.
Topics: Cardiovascular Diseases; Coronary Disease; Homocysteine; Humans; Kidney; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Models, Genetic; Neoplasms; Neurodegenerative Diseases; Pharmacogenetics; Polymorphism, Genetic; Risk; Risk Factors | 2008 |
Homocysteine and neurologic disease.
Topics: Brain Diseases; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Pyridoxine; Vascular Diseases; Vitamin B 12 | 2000 |
Folic acid and homocysteine in age-related disease.
Topics: Aged; Aging; Cardiovascular Diseases; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Mental Disorders; Neoplasms; Neurodegenerative Diseases; Stroke | 2002 |
25 other study(ies) available for homocysteine and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Conundrum of dehydroascorbic acid and homocysteine thiolactone reaction products: Structural characterization and effect on peptide and protein N-homocysteinylation.
Topics: Dehydroascorbic Acid; Homocysteine; Humans; Neurodegenerative Diseases; Peptides | 2023 |
Homocysteine aggravates DNA damage by impairing the FA/Brca1 Pathway in NE4C murine neural stem cells.
Topics: Animals; Apoptosis; BRCA1 Protein; Cell Line; Chromatin; Culture Media; DNA Damage; DNA Repair; Fanconi Anemia Complementation Group D2 Protein; Fanconi Anemia Complementation Group Proteins; Homocysteine; Humans; Mice; Mitomycin; Neural Stem Cells; Neurodegenerative Diseases; Signal Transduction; Ubiquitination | 2020 |
Genetic absence of ALOX5 protects from homocysteine-induced memory impairment, tau phosphorylation and synaptic pathology.
Topics: Animals; Arachidonate 5-Lipoxygenase; Brain; Disease Models, Animal; Female; Homocysteine; Humans; Male; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurodegenerative Diseases; Phosphorylation; Synapses | 2017 |
[A new link between high homocysteine levels, cancers and neurodegenerative diseases].
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Methionine; Neoplasms; Neurodegenerative Diseases; Risk Factors | 2017 |
Postnatal Administration of Homocysteine Induces Cerebellar Damage in Rats: Protective Effect of Folic Acid.
Topics: Animals; Antioxidants; Cerebellar Diseases; Cerebellum; Folic Acid; Homocysteine; Lipid Peroxidation; Male; Motor Cortex; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Random Allocation; Rats, Wistar | 2019 |
The sulfite molecule enhances homocysteine toxicity in SH-SY5Y cells.
Topics: Amino Acids, Sulfur; Antioxidants; Cell Line, Tumor; Comet Assay; DNA Damage; Homocysteine; Humans; Lipid Peroxidation; Neurodegenerative Diseases; Oxidative Stress; Sulfite Oxidase; Sulfites | 2019 |
Inactivation of the paraoxonase 1 gene affects the expression of mouse brain proteins involved in neurodegeneration.
Topics: Animals; Aryldialkylphosphatase; Brain; Diet; Electrophoresis, Polyacrylamide Gel; Homocysteine; Methionine; Mice, Inbred C57BL; Mice, Knockout; Neurodegenerative Diseases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Fatty acids rehabilitated long-term neurodegenerative: like symptoms in olfactory bulbectomized rats.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Body Temperature Regulation; Brain; Cholesterol; Cytokines; Disease Models, Animal; Eating; Fatty Acids; Homocysteine; Iron; Male; Maze Learning; Motor Activity; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Olfactory Bulb; Rats, Long-Evans; Synaptosomes | 2015 |
Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases.
Topics: Animals; Catalase; Cell Line, Tumor; Chromatography, High Pressure Liquid; Enzyme Activation; Heme; Homocysteine; Hydrogen Sulfide; Iron; Male; Mass Spectrometry; Mice, Inbred C57BL; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Oxygen; Sulfhydryl Compounds | 2016 |
Serum homocysteine levels in relation to clinical progression in multiple sclerosis.
Topics: Adult; Case-Control Studies; Disease Progression; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Neurodegenerative Diseases; Neurology; Risk Factors | 2008 |
Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2-dependent cyclin E expression.
Topics: Adult Stem Cells; Aged; Aged, 80 and over; Animals; Cell Proliferation; Cells, Cultured; Cognition Disorders; Cyclin E; Dementia; Dentate Gyrus; Disease Models, Animal; Fibroblast Growth Factor 2; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurodegenerative Diseases; Neurons; Trigeminal Caudal Nucleus | 2008 |
Common key-signals in learning and neurodegeneration: focus on excito-amino acids, beta-amyloid peptides and alpha-synuclein.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Animals; Brain; Dopamine; Glutamic Acid; Homocysteine; Humans; Learning; Models, Neurological; Nerve Degeneration; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Protein Conformation; Protein Multimerization; Signal Transduction | 2009 |
Redox homeostasis and cellular stress response in aging and neurodegeneration.
Topics: Acetylcarnitine; Aging; Animals; Carbon Monoxide; Gene Regulatory Networks; Heme Oxygenase-1; Homeostasis; Homocysteine; HSP70 Heat-Shock Proteins; Humans; Nerve Degeneration; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Stress, Physiological | 2010 |
Homocysteine: a biomarker in neurodegenerative diseases.
Topics: Biomarkers; Homocysteine; Humans; Neurodegenerative Diseases; Vitamin B 12 Deficiency | 2011 |
Metabolism and neurotoxicity of homocysteine thiolactone in mice: protective role of bleomycin hydrolase.
Topics: Animals; Blood Proteins; Brain; Cysteine Endopeptidases; Female; Half-Life; Homocysteine; Hyperhomocysteinemia; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurodegenerative Diseases; Organ Specificity; Seizures | 2012 |
[A case of subacute combined degeneration with normal serum vitamin B12 level].
Topics: Adult; Anemia, Megaloblastic; Female; Homocysteine; Humans; Neurodegenerative Diseases; Pancytopenia; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate.
Topics: Analgesics, Opioid; Animals; Caspases; Cell Death; Cell Line; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Homocysteine; Hyperhomocysteinemia; Neurodegenerative Diseases; Neuroprotective Agents; Pentazocine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Retinal Ganglion Cells | 2004 |
The S-adenosyl homocysteine hydrolase inhibitor 3-deaza-adenosine prevents oxidative damage and cognitive impairment following folate and vitamin E deprivation in a murine model of age-related, oxidative stress-induced neurodegeneration.
Topics: Adenosylhomocysteinase; Animals; Apolipoproteins E; Brain; Brain Chemistry; Cognition Disorders; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Female; Folic Acid Deficiency; Homocysteine; Male; Methionine; Mice; Mice, Knockout; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Tubercidin; Vitamin E Deficiency | 2004 |
Embryonic cerebellar granule cells are resistant to necrosis induced by homocysteine.
Topics: Aging; Animals; Animals, Newborn; Cells, Cultured; Disease Susceptibility; Homocysteine; Hyperhomocysteinemia; Mice; Microscopy, Electron, Transmission; Necrosis; Neurodegenerative Diseases; Neurons | 2005 |
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12 | 2005 |
Homocysteine and cognition--no longer a hypothesis?
Topics: Aged; Alzheimer Disease; Cognition; Cognition Disorders; Homocysteine; Humans; Methionine; Models, Biological; Models, Theoretical; Neurodegenerative Diseases; Vitamin B 12; Vitamins | 2006 |
Binding of copper is a mechanism of homocysteine toxicity leading to COX deficiency and apoptosis in primary neurons, PC12 and SHSY-5Y cells.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Cells, Cultured; Chelating Agents; Copper; Cytochrome-c Oxidase Deficiency; Dose-Response Relationship, Drug; Electron Transport Complex IV; Homocysteine; Humans; Hyperhomocysteinemia; Menkes Kinky Hair Syndrome; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; PC12 Cells; Rats | 2006 |
Glutathione depletion in hippocampal cells increases levels of H and L ferritin and glutathione S-transferase mRNAs.
Topics: Animals; Apoferritins; Base Sequence; Cell Line; DNA Primers; Gene Expression Profiling; Glutathione; Glutathione Transferase; Hippocampus; Homocysteine; Humans; Mice; Neurodegenerative Diseases; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Effects of homocysteine on metabolic pathways in cultured astrocytes.
Topics: Animals; Astrocytes; Brain; Cell Death; Cells, Cultured; Choline; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Homocysteine; Magnetic Resonance Spectroscopy; Membrane Potential, Mitochondrial; Mitochondria; NADP; Neurodegenerative Diseases; Protein Serine-Threonine Kinases; Pyruvate Carboxylase; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Rats; Rats, Wistar; Taurine | 2008 |
Food (and vitamins) for thought.
Topics: Cognition; Food; Homocysteine; Humans; Neurodegenerative Diseases; Vitamins | 2002 |