Compounds > homocysteine

homocysteine and Colorectal Cancer

homocysteine has been researched along with Colorectal Cancer in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (5.88)18.2507
2000's25 (49.02)29.6817
2010's20 (39.22)24.3611
2020's3 (5.88)2.80

Authors

AuthorsStudies
Barták, BK; Dank, M; Fodor, T; Igaz, P; Kalmár, A; Molnár, B; Nagy, ZB; Szigeti, KA; Takács, I; Valcz, G; Zsigrai, S1
Chen, P; He, Q; Jiang, J; Liu, L; Shi, H; Song, Y; Tang, Y; Wang, B; Zhang, N; Zhou, H; Zhou, Z1
Chao, TH; Cheng, CH; Chiang, FF; Huang, SC; Huang, YC; Tseng, YY1
Gylling, B; Häggström, J; Hallmans, G; Johansson, I; Midttun, Ø; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Ulvik, A; Van Guelpen, B1
Jakubowski, H1
Cho, E; Fuchs, CS; Giovannucci, EL; Nan, H; Paul, L; Rosner, B; Selhub, J; Wu, K1
Chrudinová, M; Demianová, Z; Jiráček, J; Kořínek, M; Mládková, J; Selicharová, I1
Chiang, FF; Huang, SC; Huang, YC; Lan, YC; Wang, HM; Yang, MH1
Chiarugi, M; Consolini, R; Coppedè, F; Failli, A; Fontanini, G; Legitimo, A; Lopomo, A; Migheli, F; Migliore, L; Seccia, M; Sensi, E; Servadio, A; Spisni, R; Zocco, G1
Cardoso, JF; Cohen, C; Garcia, SB; Vannucchi, H1
Chen, FP; Chiang, FF; Huang, SC; Huang, YC; Wang, HM1
Baracos, VE; Keshteli, AH; Madsen, KL1
Boyd, L; Choi, JH; Kim, J; Lucock, M; Martin, C; Ng, X; Skinner, V; Veysey, M; Wai, R; Woo, HD; Yates, Z1
Hwang, SG; Jang, HG; Jeon, YJ; Kim, JO; Kim, JW; Kim, NK; Kwon, SW; Oh, D; Oh, J; Park, HM1
Cho, SH; Jeon, YJ; Kim, JO; Kim, JW; Kim, NK; Ko, JJ; Oh, D; Oh, J; Yoo, JK1
Adams, PD; Labuschagne, CF; Maddocks, OD; Vousden, KH1
Brandslund, I; Crüger, DG; Jakobsen, A; Jensen, LH; Kolvraa, S; Lindebjerg, J; Nielsen, JN1
Choi, SW; Mason, JB; Sauer, J1
Eklöf, V; Hallmans, G; Hultdin, J; Johansson, I; Palmqvist, R; Van Guelpen, B1
Deng, L; Lawrance, AK; Rozen, R1
Croxford, R; Depeint, F; Kim, YI; Lindzon, GM; Medline, A; Sohn, KJ1
Ciatti, F; Del Monte, G; Ferroni, P; Guadagni, F; Mariotti, S; Martini, F; Palmirotta, R; Riondino, S; Roselli, M; Savonarola, A; Sini, V; Spila, A1
Cullman, I; Dahlin, AM; Eklöf, V; Hallmans, G; Henriksson, ML; Hultdin, J; Johansson, I; Palmqvist, R; Van Guelpen, B1
Hyspler, R; Kalábová, H; Kasparová, M; Krcmová, L; Malírová, E; Melichar, B; Melicharová, K; Pecka, M; Solichová, D1
Albert, PS; Bobe, G; Cross, AJ; Hance, KW; Laiyemo, AO; Lanza, E; Murphy, G; Rogers, CJ; Sansbury, LB; Schatzkin, A1
Baron, JA; Grau, MV; Levine, AJ; Mott, LA; Ueland, PM1
Adleff, V; Budai, B; Hitre, E; Komlósi, V; Kralovánszky, J; Láng, I; Nagy, T; Pap, É; Réti, A1
Blassnigg, SM; Bulmer, AC; Doberer, D; Knasmüller, S; Marculescu, R; Marisch, K; Mölzer, C; Müllner, E; Nersesyan, A; Pappenheim, MT; Wagner, KH; Wallner, M1
Bal, W; Duckworth, Y; Gibney, ER; Hill, MH; Mathers, JC; Powers, HJ; Spiers, A; Welfare, M; Williams, EA1
Baurley, J; Crott, JW; Figueiredo, JC; Haile, RW; Levine, AJ1
Alberts, DS; Henning, SM; Martínez, ME1
Basten, G; Duthie, SJ; Little, J; McConnell, J; Narayanan, S; Piyathilake, CJ; Powers, H; Sharp, L1
Chun, HK; Hwang, NC; Kim, JJ; Kim, YH; Paik, SW; Rhee, JC; Rhee, PL; Shim, SG; Son, HJ1
Al-Ghnaniem, R; Appleby, P; Emery, PW; Gout, S; Harris, N; Khushal, A; Pufulete, M; Sanders, TA1
Beale, P; Clarke, SJ; Horvath, L; Ong, S; Rivory, L; Sharma, R1
Alberts, DS; Giovannucci, E; Henning, SM; Jacobs, ET; Jiang, R; Martínez, ME; Smith-Warner, SA; Thompson, P1
Hallmans, G; Hultdin, J; Johansson, I; Palmqvist, R; Riboli, E; Stenling, R; Van Guelpen, B; Winkvist, A1
Battistelli, S; Bing, C; Roviello, F; Stefanoni, M; Vittoria, A1
Alberts, DS; Giovannucci, E; Jacobs, ET; Jiang, R; Klimecki, W; Martínez, ME; Thompson, P1
Phelip, JM; Roblin, X1
Akhgar, A; Ashktorab, H; Begum, R; Daremipouran, M; Elbedawi, M; Giardiello, FM; Momen, B; Smoot, DT; Zhao, A1
Alonso-Aperte, E; González, MP; Póo-Prieto, R; Varela-Moreiras, G1
Crott, JW; de Boer, SY; Friederich, P; Kampman, E; Keijer, J; Kok, FJ; Mason, JB; Nagengast, FM; Pellis, L; van Bergeijk, JD; van den Donk, M; van Engeland, M1
Al-Ghnaniem, R; Foresti, R; Heaton, N; Peters, J; Pufulete, M1
Dahlin, AM; Hallmans, G; Hultdin, J; Johansson, I; Palmqvist, R; Van Guelpen, B1
Geisler, J; Geisler, SB; Lønning, PE; Refsum, H; Smaaland, R; Tveit, KM; Ueland, PM1
Akhmedkhanov, A; Dnistrian, AM; Kato, I; Koenig, K; Riboli, E; Schwartz, M; Shore, RE; Toniolo, P; Zeleniuch-Jacquotte, A1
Chen, J; Christensen, B; Giovannucci, E; Gravel, R; Hennekens, CH; Hunter, DJ; Ma, J; Rozen, R; Selhub, J; Stampfer, MJ; Willett, WC1
Evensen, ET; Hoff, G; Lien, EA; Majak, BM; Ueland, PM; Ulvik, A; Vollset, SE1
Molloy, AM; Scott, JM1
Fohr, I; Pietrzik, K; Prinz-Langenohl, R1

Reviews

5 review(s) available for homocysteine and Colorectal Cancer

ArticleYear
Hyperhomocysteinemia as a potential contributor of colorectal cancer development in inflammatory bowel diseases: a review.
    World journal of gastroenterology, 2015, Jan-28, Volume: 21, Issue:4

    Topics: Biomarkers; Cell Transformation, Neoplastic; Colorectal Neoplasms; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Prognosis; Risk Assessment; Risk Factors

2015
Too much folate: a risk factor for cancer and cardiovascular disease?
    Current opinion in clinical nutrition and metabolic care, 2009, Volume: 12, Issue:1

    Topics: Adenoma; Cardiovascular Diseases; Chronic Disease; Colorectal Neoplasms; Dietary Supplements; Dose-Response Relationship, Drug; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Neoplasms; Risk Factors

2009
Folate-genetics and colorectal neoplasia: what we know and need to know next.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:4

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Colorectal Neoplasms; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Randomized Controlled Trials as Topic; Risk Factors; S-Adenosylmethionine; Thymidylate Synthase

2013
Folates and prevention of disease.
    Public health nutrition, 2001, Volume: 4, Issue:2B

    Topics: Cardiovascular Diseases; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Food, Fortified; Homocysteine; Humans; Mental Disorders; Neural Tube Defects; Treatment Outcome

2001
Beneficial role for folate in the prevention of colorectal and breast cancer.
    European journal of nutrition, 2001, Volume: 40, Issue:3

    Topics: Breast Neoplasms; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Methylation; Prospective Studies; Risk Factors

2001

Trials

6 trial(s) available for homocysteine and Colorectal Cancer

ArticleYear
Baseline plasma total homocysteine and adenoma recurrence: results from a double blind randomized clinical trial of aspirin and folate supplementation.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:10

    Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aspirin; Colorectal Neoplasms; Double-Blind Method; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Surveys and Questionnaires; Young Adult

2010
Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma.
    Gut, 2005, Volume: 54, Issue:5

    Topics: Adenoma; Aged; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; DNA, Neoplasm; Double-Blind Method; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Leukocytes; Male; Middle Aged; Rectum

2005
A phase II study of fixed-dose capecitabine and assessment of predictors of toxicity in patients with advanced/metastatic colorectal cancer.
    British journal of cancer, 2006, Apr-10, Volume: 94, Issue:7

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Diarrhea; Disease Progression; Fatigue; Female; Fluorouracil; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neoplasm Metastasis; Predictive Value of Tests; Survival Analysis

2006
Folate fortification, plasma folate, homocysteine and colorectal adenoma recurrence.
    International journal of cancer, 2006, Sep-15, Volume: 119, Issue:6

    Topics: Adenoma; Aged; Colorectal Neoplasms; Diet; Dietary Fiber; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Neoplasm Recurrence, Local; Risk Factors; Ursodeoxycholic Acid; Vitamin B Complex

2006
Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas.
    The Journal of nutrition, 2007, Volume: 137, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Promoter Regions, Genetic; Uracil; Vitamin B 12

2007
Changes in folate status as determined by reduction in total plasma homocysteine levels during leucovorin modulation of 5-fluorouracil therapy in cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colorectal Neoplasms; Creatinine; Erythrocytes; Female; Fluorouracil; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Middle Aged; Vitamin B 12

1998

Other Studies

40 other study(ies) available for homocysteine and Colorectal Cancer

ArticleYear
A Liquid Biopsy-Based Approach for Monitoring Treatment Response in Post-Operative Colorectal Cancer Patients.
    International journal of molecular sciences, 2022, Mar-29, Volume: 23, Issue:7

    Topics: Biomarkers, Tumor; Cell-Free Nucleic Acids; Colorectal Neoplasms; DNA Methylation; Homocysteine; Humans; Liquid Biopsy; Neoplasm Recurrence, Local

2022
A sensitive UPLC-MS/MS method for simultaneous quantification of one-carbon metabolites & co-factors in human plasma.
    Journal of pharmaceutical and biomedical analysis, 2022, Sep-20, Volume: 219

    Topics: Carbon; Chromatography, High Pressure Liquid; Chromatography, Liquid; Colorectal Neoplasms; Cystathionine; Homocysteine; Humans; Methionine; Tandem Mass Spectrometry

2022
Cysteine Regulates Oxidative Stress and Glutathione-Related Antioxidative Capacity before and after Colorectal Tumor Resection.
    International journal of molecular sciences, 2022, Aug-24, Volume: 23, Issue:17

    Topics: Advanced Oxidation Protein Products; Antioxidants; Colorectal Neoplasms; Cysteine; Glutathione; Homocysteine; Humans; Malondialdehyde; Oxidative Stress

2022
One-carbon metabolite ratios as functional B-vitamin markers and in relation to colorectal cancer risk.
    International journal of cancer, 2019, 03-01, Volume: 144, Issue:5

    Topics: Betaine; Biomarkers, Tumor; Carbon; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Vitamin B 12; Vitamin B Complex

2019
Protein N-Homocysteinylation and Colorectal Cancer.
    Trends in cancer, 2019, Volume: 5, Issue:1

    Topics: Colorectal Neoplasms; DNA Repair; Homocysteine; Humans; Metabolic Networks and Pathways; Protein Processing, Post-Translational

2019
Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Adult; Case-Control Studies; Colorectal Neoplasms; Cysteine; DNA Methylation; DNA, Neoplasm; Female; Health Surveys; Homocysteine; Humans; Leukocytes, Mononuclear; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Pyridoxal Phosphate; Risk Factors

2013
Effects of hyperhomocysteinemia and betaine-homocysteine S-methyltransferase inhibition on hepatocyte metabolites and the proteome.
    Biochimica et biophysica acta, 2013, Volume: 1834, Issue:8

    Topics: Apolipoprotein A-I; Apoptosis; Betaine-Homocysteine S-Methyltransferase; Blotting, Western; Cell Proliferation; Cells, Cultured; Colorectal Neoplasms; Electrophoresis, Gel, Two-Dimensional; Fibrinogen; Hepatocytes; Homocysteine; Humans; Hyperhomocysteinemia; Liver Neoplasms; Male; Metabolomics; Middle Aged; Protein Multimerization; Proteome; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2013
High homocysteine is associated with increased risk of colorectal cancer independently of oxidative stress and antioxidant capacities.
    Clinical nutrition (Edinburgh, Scotland), 2014, Volume: 33, Issue:6

    Topics: Adult; Aged; Antioxidants; Blood Pressure; Body Mass Index; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Glutathione Peroxidase; Glutathione Transferase; Healthy Volunteers; Homocysteine; Humans; Linear Models; Male; Middle Aged; Oxidative Stress; Pyridoxal Phosphate; Risk Factors; Serum Albumin; Superoxide Dismutase

2014
Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism.
    Epigenetics, 2014, Volume: 9, Issue:4

    Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Colon; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Metabolic Networks and Pathways; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic; Rectum; Vitamin B 12

2014
Vitamin E supplementation in chemical colorectal carcinogenesis: a two-edged knife.
    Nutrients, 2014, Aug-13, Volume: 6, Issue:8

    Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Biomarkers; Carcinogenesis; Carcinogens; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glutathione; Homocysteine; Immunohistochemistry; Male; Multivariate Analysis; Oxidative Stress; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Recommended Dietary Allowances; Vitamin E; Weight Gain

2014
High serum folate might have a potential dual effect on risk of colorectal cancer.
    Clinical nutrition (Edinburgh, Scotland), 2015, Volume: 34, Issue:5

    Topics: Adult; Aged; Body Mass Index; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pyridoxal Phosphate; Risk Factors

2015
Genetic Variation in Glutamate Carboxypeptidase II and Interaction with Dietary Natural Vitamin C May Predict Risk for Adenomatous Polyp Occurrence.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:10

    Topics: Adenomatous Polyps; Adult; Aged; Aged, 80 and over; Ascorbic Acid; Case-Control Studies; Colorectal Neoplasms; Diet; Folic Acid; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Middle Aged; Polymorphism, Single Nucleotide; Pteroylpolyglutamic Acids; Risk Factors; Tetrahydrofolates; Vitamins

2015
Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.
    Scientific reports, 2015, Jun-05, Volume: 5

    Topics: 3' Untranslated Regions; Adenocarcinoma; Aged; Colorectal Neoplasms; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Republic of Korea

2015
3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: 3' Untranslated Regions; Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; DEAD-box RNA Helicases; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Karyopherins; Male; MicroRNAs; Middle Aged; Polymorphism, Single Nucleotide; ran GTP-Binding Protein; Republic of Korea; Ribonuclease III; Risk; RNA, Neoplasm; Tumor Burden

2015
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.
    Molecular cell, 2016, Jan-21, Volume: 61, Issue:2

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Homocysteine; Humans; Methionine; Neoplasms; RNA; S-Adenosylmethionine; Serine; Stress, Physiological

2016
Microsatellite instability and the association with plasma homocysteine and thymidylate synthase in colorectal cancer.
    Cancer investigation, 2008, Volume: 26, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Aged; Aged, 80 and over; Carcinoembryonic Antigen; Colorectal Neoplasms; DNA Methylation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Microsatellite Instability; Middle Aged; MutL Protein Homolog 1; Nuclear Proteins; Nutritional Status; Polymorphism, Genetic; Promoter Regions, Genetic; Thymidylate Synthase

2008
The reduced folate carrier (RFC1) 80G > A and folate hydrolase 1 (FOLH1) 1561C > T polymorphisms and the risk of colorectal cancer: a nested case-referent study.
    Scandinavian journal of clinical and laboratory investigation, 2008, Volume: 68, Issue:5

    Topics: Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Membrane Transport Proteins; Middle Aged; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk Factors

2008
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
    Gut, 2009, Volume: 58, Issue:6

    Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Colorectal Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Pregnancy; Prenatal Nutritional Physiological Phenomena; Random Allocation; Thymine Nucleotides; Uridine Triphosphate; Weaning

2009
Effect of folic acid supplementation on the progression of colorectal aberrant crypt foci.
    Carcinogenesis, 2009, Volume: 30, Issue:9

    Topics: Animals; Cell Proliferation; Colorectal Neoplasms; Dietary Supplements; Disease Progression; Folic Acid; Homocysteine; Liver; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley

2009
Determinants of homocysteine levels in colorectal and breast cancer patients.
    Anticancer research, 2009, Volume: 29, Issue:10

    Topics: Adult; Breast Neoplasms; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Inflammation Mediators; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Status; Polymorphism, Single Nucleotide

2009
One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent study.
    Cancer causes & control : CCC, 2010, Volume: 21, Issue:4

    Topics: Aged; Carbon; Case-Control Studies; Colorectal Neoplasms; CpG Islands; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Sweden; Vitamin B 12

2010
Serum homocysteine, cholesterol, retinol, alpha-tocopherol, glycosylated hemoglobin and inflammatory response during therapy with bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin.
    Anticancer research, 2009, Volume: 29, Issue:11

    Topics: Adult; Aged; alpha-Tocopherol; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Atherosclerosis; Bevacizumab; Cholesterol; Colorectal Neoplasms; Female; Fluorouracil; Glycated Hemoglobin; Homocysteine; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Vitamin A

2009
Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention Trial.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:6

    Topics: Adenoma; Adiponectin; Adult; Aged; Aged, 80 and over; C-Peptide; Colorectal Neoplasms; Diet; Female; Follow-Up Studies; Homocysteine; Humans; Leptin; Male; Middle Aged; Neoplasm Recurrence, Local; Recurrence; Risk Factors

2010
Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:1

    Topics: 3' Untranslated Regions; 5' Untranslated Regions; Alleles; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Creatinine; Dihydrouracil Dehydrogenase (NADP); Disease-Free Survival; Fluorouracil; Genetic Association Studies; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Hypertension; INDEL Mutation; Leucovorin; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Prognosis; Thymidylate Synthase; Treatment Outcome

2012
Effects of unconjugated bilirubin on chromosomal damage in individuals with Gilbert's syndrome measured with the micronucleus cytome assay.
    Mutagenesis, 2012, Volume: 27, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bilirubin; Chromosome Aberrations; Colorectal Neoplasms; Comet Assay; Cytokinesis; DNA Damage; Endpoint Determination; Female; Folic Acid; Gilbert Disease; Homocysteine; Humans; Lung Neoplasms; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Vitamin B 12; Young Adult

2012
Systemic folate status, rectal mucosal folate concentration and dietary intake in patients at differential risk of bowel cancer (The FAB2 Study).
    European journal of nutrition, 2013, Volume: 52, Issue:7

    Topics: Cohort Studies; Colorectal Neoplasms; Diet; Erythrocytes; Female; Folic Acid; Glutathione Reductase; Homocysteine; Humans; Intestinal Mucosa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutrition Assessment; Nutritional Status; Risk Factors; Surveys and Questionnaires; Tetrahydrofolates; Vitamin B 12

2013
Folate and colorectal neoplasia: relation between plasma and dietary markers of folate and adenoma recurrence.
    The American journal of clinical nutrition, 2004, Volume: 79, Issue:4

    Topics: Adenoma; Adult; Aged; Colorectal Neoplasms; Diet; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Neoplasm Recurrence, Local; Risk Factors; Surveys and Questionnaires

2004
Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; DNA Damage; DNA Methylation; Erythrocytes; Female; Folic Acid; Genetic Carrier Screening; Genetic Variation; Genotype; Homocysteine; Homozygote; Humans; Isoenzymes; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Scotland; Tetrahydrofolates; Uracil; Vitamin B 12

2004
[Is serum homocysteine level elevated in colorectal tumor?].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2005, Volume: 45, Issue:2

    Topics: Adenomatous Polyps; Alcohol Drinking; Colonoscopy; Colorectal Neoplasms; Female; Homocysteine; Humans; Male; Middle Aged

2005
Low folate levels may protect against colorectal cancer.
    Gut, 2006, Volume: 55, Issue:10

    Topics: Adult; Aged; Colorectal Neoplasms; Epidemiologic Methods; Folic Acid Deficiency; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic

2006
Total plasma homocysteine and methylenetetrahydrofolate reductase C677T polymorphism in patients with colorectal carcinoma.
    World journal of gastroenterology, 2006, Oct-14, Volume: 12, Issue:38

    Topics: Aged; Carcinoma; Cell Proliferation; Colorectal Neoplasms; Cytosine; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Thymine

2006
Dietary factors and biomarkers involved in the methylenetetrahydrofolate reductase genotype-colorectal adenoma pathway.
    Gastroenterology, 2006, Volume: 131, Issue:6

    Topics: Adenoma; Aged; Biomarkers, Tumor; Carbon; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; Female; Folic Acid; Genotype; Homeostasis; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Polymorphism, Genetic; Prospective Studies; Risk Factors; Vitamins

2006
Type 2 diabetes mellitus and colorectal cancer risk: is homocysteine the missing link?
    The American journal of gastroenterology, 2007, Volume: 102, Issue:2

    Topics: Biomarkers; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Risk Factors

2007
Folate status and risk of colorectal polyps in African Americans.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:6

    Topics: Adenoma; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Black or African American; Case-Control Studies; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Genes, APC; Homocysteine; Humans; Male; Middle Aged; Promoter Regions, Genetic; Smoking; Tetrahydrofolates; Vitamin B 12; Vitamins

2007
Folate status and S-adenosylmethionine/S-adenosylhomocysteine ratio in colorectal adenocarcinoma in humans.
    European journal of clinical nutrition, 2008, Volume: 62, Issue:2

    Topics: Adenocarcinoma; Aged; Colon; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine

2008
Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Adenoma; Aged; Base Sequence; Biomarkers; Case-Control Studies; Colon; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Estrogen Receptor alpha; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; MutL Protein Homolog 1; Nuclear Proteins; Nutritional Status; Vitamin B 12

2007
Plasma vitamin B12 concentrations and the risk of colorectal cancer: a nested case-referent study.
    International journal of cancer, 2008, May-01, Volume: 122, Issue:9

    Topics: Adult; Aged; Analysis of Variance; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Assessment; Risk Factors; Sweden; Vitamin B 12

2008
Serum folate, homocysteine and colorectal cancer risk in women: a nested case-control study.
    British journal of cancer, 1999, Volume: 79, Issue:11-12

    Topics: Aged; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Multivariate Analysis; Risk Factors

1999
A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:9

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Canada; Case-Control Studies; Colorectal Neoplasms; Folic Acid; Genotype; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors; Surveys and Questionnaires; United States; Vitamin B 12; White People

1999
Smoking, folate and methylenetetrahydrofolate reductase status as interactive determinants of adenomatous and hyperplastic polyps of colorectum.
    American journal of medical genetics, 2001, Jul-01, Volume: 101, Issue:3

    Topics: Adenomatous Polyps; Aged; Colorectal Neoplasms; Cross-Sectional Studies; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperplasia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Smoking

2001