homocysteine and Cognitive Dysfunction

homocysteine has been researched along with Cognitive Dysfunction in 118 studies

Research

Studies (118)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's79 (66.95)24.3611
2020's39 (33.05)2.80

Authors

AuthorsStudies
Feng, Y; Huang, X; Huang, Y; Li, H; Wu, F; Wu, K; Yang, M; Zhou, S1
Bruin, N; Geisslinger, G; Nieraad, H; Pannwitz, N; Till, U1
de Paula, AMB; Engedal, K; Felício, LFF; Kristiansen, KM; Leão, LL; Monteiro-Junior, RS; Santos, SHS; Tangen, GG1
Christine, CW; Green, R1
Enomoto, S; Hamano, T; Ikawa, M; Ito, T; Kimura, H; Kimura, Y; Kuriyama, M; Nagata, M; Nakamoto, Y; Shirafuji, N; Ueno, A; Yamamura, O; Yamanaka, D1
Chen, YX; Qian, LJ; Tian, YR; Wang, SD; Wang, X; Wang, XT; Xie, F; Xue, BH; Zhang, ZQ; Zhao, Y1
Kulisevsky, J; Martínez-Horta, S; Sampedro, F1
Andrieu, S; Bowman, GL; Cantet, C; de Souto Barreto, P; Maltais, M; Rolland, Y; Smith, AD1
Chen, Y; Du, Y; Duan, H; Fu, J; Huang, G; Huang, L; Li, W; Li, Z; Liu, H; Liu, Q; Ma, F; Sun, C; Wang, G; Wang, Z; Zhang, X; Zhao, J; Zhou, D; Zhu, Y1
Duan, Z; Fang, Q; Hou, H; Sun, G; Tao, L; Zhang, S1
Huang, F; Lin, S; Wang, F; Yuan, Y; Zheng, J; Zhu, P1
Ren, W; Zhou, XS1
Feng, Y; Huang, X; Huang, Y; Kuang, Q; Li, H; Wu, F; Wu, K; Yan, S; Zhou, S1
Cicognola, C; Frölich, K; Londos, E; Nyholm, E; Torkpoor, R1
Gong, X; Kwok, T; Luo, Y; Shi, L; Wu, Y1
Cheong, CY; Chong, MS; Gao, Q; Gwee, X; Lee, TS; Liew, TM; Lim, WS; Ng, TP; Przybycien-Gaweda, PM; Rawtaer, I; Yap, KB; Yap, P1
Jia, J; Li, T; Quan, M; Song, Y1
Adarmes-Gómez, AD; Bonilla-Toribio, M; Buiza-Rueda, D; Gómez-Garre, P; Jesús, S; Jimenez-Jaraba, MV; Macías-García, D; Martín-Rodríguez, JF; Mir, P; Muñoz-Delgado, L; Periñán, MT1
Alexander, GE; Bharadwaj, PK; Habeck, CG; Hishaw, GA; Huentelman, MJ; Raichlen, DA; Song, H; Trouard, TP1
Futschek, IE; Haslacher, H; Lehrner, J; Schernhammer, E; Stögmann, E1
Bottiglieri, T; Fardo, DW; Johnson, SN; Qiao, Q; Rogers, CB; Sudduth, TL; Weekman, EM; Wilcock, DM; Xie, K1
Gou, M; Guo, X; Liu, Y1
An, P; Chen, H; Du, Y; Gao, Y; Huang, G; Ji, Y; Liu, S; Lv, X; Ma, F; Song, A; Sun, C; Wang, G; Wang, X; Xu, W; Zhao, J; Zhou, X1
Andrieu, S; Araujo de Carvalho, I; Beard, J; de Souto Barreto, P; Giudici, KV; Guerville, F; Rolland, Y; Vellas, B1
Berge, G; Bråthen, G; Edlund, AK; Giannisis, A; Grøntvedt, GR; Lauridsen, C; Nielsen, HM; Patra, K; Sando, SB; White, LR1
An, Y; Feng, L; Qin, Z; Tao, L; Wang, Y; Xiao, R; Zhang, X1
Agustina, PS; Angianto, AR; Damanik, J; Kristanti, M; Mayza, A; Prawiroharjo, P; Rachman, A; Sauriasari, R; Yunir, E1
Guo, J; Li, Y; Meng, H; Niu, X; Zhang, W; Zhao, Y1
Choi, G; Harrison, J; Kwok, T; Lam, L; Lee, J; Lee, R; Lee, V; Mok, V; Wu, Y; Yung, CY1
Jun, JB; Kim, HJ; Kim, YS; Sohn, IW1
Bogatova, K; Gerasimova, E; Hermann, A; Mukhtarova, R; Shakhmatova, V; Sitdikova, G; Yakovlev, A; Yakovleva, O; Ziyatdinova, G1
Hasegawa, T; Kosoku, Y; Kudoh, C; Sano, Y; Tabira, T; Yoshida, H1
Chen, B; Chen, X; Dai, C; Huang, X; Liang, W; Mai, N; Ning, Y; Ouyang, C; Peng, Q; Wu, Z; Zhang, M; Zhang, W; Zhong, X; Zhou, H1
Bushnell, CD; Kim, HJ; Kim, HY; Kim, YS; Ryu, CH; Yoo, JS1
Bing, Q; Chang, KJ; Guo, X; Hu, J; Li, N; Shen, HR; Zhao, Z1
Jiang, B; Yao, C; Yao, G; Zheng, N1
Ji, Y; Jin, W; Li, X; Lv, PY; Teng, Z1
Arocha-Oriol, C; Calvo-Rodríguez, M; Díaz-Domínguez, M; Eugenia, M; García-Klibanski, M; Guerra-Hernández, M; Herrera-Javier, D; Jesús, J; Lanyau-Domínguez, Y; Macías-Matos, C; María, G; Noriega-Fernández, L; Sánchez-Gil, Y; Suárez-Medina, R1
Gabelli, C; Reffo, A1
Refsum, H; Smith, AD2
Chen, Y; Du, Y; Fu, J; Huang, G; Jin, M; Li, W; Lin, H; Liu, H; Liu, Q; Ma, F; Sun, C; Sun, Z; Wang, G; Zhang, X1
Byeon, G; Byun, MS; Jeon, SY; Jung, G; Kang, KM; Kim, YK; Ko, K; Lee, DY; Lee, JH; Lee, JY; Lee, YS; Sohn, CH; Yi, D1
Cascavilla, L; Ciccone, F; D'Onofrio, G; Germano, C; Greco, A; Lauriola, M; Paris, F1
Fujisawa, C; Huang, CH; Kinoshita, F; Komiya, H; Kuzuya, M; Nagae, M; Sakurai, T; Sugimoto, T; Umegaki, H; Watanabe, K; Yamada, Y1
Chandyo, RK; Fawzi, W; Henjum, S; Hysing, M; Kvestad, I; Midttun, Ø; Shrestha, M; Shrestha, PS; Strand, TA; Thorne-Lyman, AL; Ueland, PM; Ulak, M1
Kumar, M; Modi, M; Sandhir, R1
Andel, R; Handing, EP; Kumar, N; McEvoy, CL; Small, BJ1
Liu, Y; Qin, M; Shao, LQ; Sun, ZW; Wang, T; Weng, X; Xu, XB; Zhang, YX1
Cai, R; Han, J; Huang, R; Shen, Y; Sun, J; Tian, S; Wang, S1
Berrett, AN; Brown, BL; Erickson, LD; Gale, SD; Hedges, DW1
Granic, A; Hill, TR; Jagger, C; Martin-Ruiz, C; Mathers, JC; Mendonça, N; Seal, CJ; Wesnes, KA2
Emoto, M; Fujii, H; Fukumoto, S; Inaba, M; Kabata, D; Kuwamura, Y; Mori, K; Morioka, T; Motoyama, K; Naganuma, T; Okute, Y; Shima, H; Shimono, T; Shintani, A; Shioi, A; Shoji, T; Sonoda, M1
Huang, G; Ji, L; Ma, F; Song, A; Wu, T; Zhang, M; Zhao, J1
Atienza, M; Cantero, JL; Sanchez-Espinosa, MP1
Cholerton, B; Chung, KA; Edwards, K; Hu, SC; Leverenz, JB; Licking, N; Montine, TJ; Murchison, C; Peterson-Hiller, AL; Quinn, JF; Zabetian, CP1
Fuchs, D; Gostner, J; Sperner-Unterweger, B1
Absalom, AR; de Bock, GH; Gernaat, SAM; Huisman, MG; Izaks, GJ; van der Wal-Huisman, H; van Leeuwen, BL; Weerink, LBM1
Bennett, DA; De Jager, PL; Felsky, D; Nazeri, A; Roostaei, T; Schneider, JA; Voineskos, AN1
Mowszowski, L; Naismith, SL1
Arranz, B; de la Fuente, L; Garcia-Blanco, A; García-Portilla, MP; Garriga, M; Safont, G; Sanchez-Autet, M; Sierra, P1
Li, MH; Li, X; Tang, XQ; Tang, YY; Wang, AP; Wang, CY; Wei, HJ; Zhang, P; Zou, W1
Choi, BY; Kim, MK; Kim, S; Nam, JH; Oh, DH; Yang, YJ1
Li, SS; Mei, B; Wang, HY; Zheng, J; Zheng, K; Zheng, M1
Bosi, C; Brombo, G; Cervellati, C; Morieri, ML; Passaro, A; Trentini, A; Valacchi, G; Zuliani, G; Zurlo, A1
Bottiglieri, T; Fenech, M; Hooshmand, B; McCaddon, A; Miller, JW; Obeid, R; Refsum, H; Rosenberg, IH; Smith, AD1
Lichter-Konecki, U; Sklirou, E1
Behera, J; George, AK; Kelly, KE; Mondal, NK; Richardson, KP; Tyagi, N1
Cantet, C; Chhetri, JK; de Souto Barreto, P; Gennero, I; Soriano, G; Vellas, B1
Chopra, K; Dharavath, RN; Sachdeva, AK1
Bhadelia, RA; Folstein, MF; Qiu, WQ; Rosenberg, IH; Scott, TM1
Chen, YH; Huang, LL; Liao, JH; Su, C; Xu, X; Yang, YY; Yu, H; Yu, XL; Yuan, L; Yuan, MM; Zhao, M1
Gaur, R; Kaur, G; Saraswathy, KN; Yadav, S1
Belardo, C; Boccella, S; Calignano, A; Cristiano, C; Cristino, L; de Novellis, V; Di Marzo, V; Farina, A; Guida, F; Iannotta, M; Imperatore, R; Luongo, L; Maione, S; Mazzitelli, M; Palazzo, E; Piscitelli, F; Romano, R; Tunisi, L1
Cortina-Borja, M; Lehmann, DJ1
Qu, QM; Sun, HY1
Casey, MC; Cunningham, C; Hoey, L; Hughes, CF; Laird, E; McCarroll, K; McNulty, H; Molloy, AM; Moore, K; O'Kane, M; Strain, JJ; Tracey, F; Ward, M1
Chen, S; Zhou, F1
Flitton, M; Knight, HM; Macdonald, IA; Rielly, N; Smith, AD; Warden, D; Warman, R1
Burn, DJ; Duncan, GW; Johnston, F; Khoo, TK; Lawson, RA; Sleeman, I; Yarnall, AJ1
Chang, CJ; Chen, CH; Chen, PH; Chiu, CC; Chiu, WC; Liu, HC; Liu, SI; Lu, ML; Stewart, R; Sun, IW; Tsai, SY1
Baroni, L; Bazzerla, G; Bertola, C; Bonetto, C; Caberlotto, L; Rizzo, G1
Bu, X; Chen, CS; Chen, J; Guo, D; Guo, L; He, J; Ju, Z; Li, D; Liu, J; Xu, T; Zhang, J; Zhang, Y; Zhong, C; Zhu, Z1
Kalinowska, S; Kłoda, K; Misiak, B; Safranow, K; Samochowiec, J; Trześniowska-Drukała, B1
Dong, Y; Ji, Y; Jin, W; Li, X; Lyu, P1
An, P; Du, Y; Huang, G; Song, A; Wang, Q; Zhao, J; Zhou, X1
Bergamini, CM; Bosi, C; Cervellati, C; Cremonini, E; Magon, S; Passaro, A; Pilotto, A; Romani, A; Seripa, D; Zuliani, G1
Byun, MS; Choe, YM; Choi, HJ; Han, JY; Kim, YK; Lee, DY; Lee, JM; Park, J; Seo, EH; Sohn, BK; Woo, JI; Yoon, EJ1
Cheng, D; Huang, C; Jiang, Y; Kong, H; Lu, H; Pang, W; Yang, H1
Armitage, J; Bennett, D; Clarke, R; Collins, R; Dangour, AD; de Groot, LC; Eussen, SJ; Galan, P; Grodstein, F; Halsey, J; Hankey, GJ; Lewerin, C; Lewington, S; Lonn, E; Parish, S; Skeaff, M; Spence, JD; Stott, DJ1
Das, SK; Dhar, P; Hota, KB; Hota, SK; Kumar, A; Mahapatra, BB; Norboo, T; Sharma, VK; Srivastava, RB; Vashishtha, V1
Ji, H; Liang, J; Luo, M; Zhou, X; Zou, T1
Garrard, P; Jacoby, R1
de Jager, CA; Refsum, H; Rosenberg, IH; Smith, AD1
Bennett, D; Clarke, R; Parish, S1
Calle Escobar, ML; Casado-Naranjo, I; Duque de San Juan, B; Fernández Pereira, L; Fuentes, JM; Portilla Cuenca, JC; Ramírez-Moreno, JM; Romero Sevilla, R1
Han, F; Huang, G; Liu, H; Ma, F; Marseglia, A; Wu, T; Zhao, J1
Chen, CS; Hsiao, SM; Huang, MF; Hwang, SJ; Kuo, MC; Liu, TL; Tsai, JC; Yang, YH; Yeh, YC1
Hainsworth, AH; Weekman, EM; Wilcock, DM; Yeo, NE1
Ansari, Z1
Kim, SY; Lee, HK; Sok, SR1
Bohlken, J; Flöel, A; Grittner, U; Hahn, A; Köbe, T; Pantel, J; Rujescu, D; Schnelle, A; Schuchardt, JP; Tesky, VA; Witte, AV1
Cui, Y; Kong, X; Wei, W; Wei, Y; Zhang, J; Zheng, L1
Gao, XJ; Gong, JB; Ma, J; Qian, LJ; Wang, SD; Xie, F; Zhang, L; Zhao, Y1
Gao, X; Li, YG; Scott, T; Tucker, KL; Wilde, P; Wong, JC1
Apostolopoulos, V; Bosevski, M; Mikkelsen, K; Stojanovska, L; Tangalakis, K1
Andel, R; Gažová, I; Hort, J; Laczó, J; Lerch, O; Marková, H; Pařízková, M; Vyhnálek, M1
Harrison, J; Ho, CS; Kung, K; Kwok, T; Lam, A; Lam, L; Lee, J; Lee, V; Ma, RC; Wong, SY1
Davies, K; de Craen, AJ; den Elzen, WP; Granic, A; Gussekloo, J; Harrison, SL; Jagger, C; Kerse, N; Kirkwood, TB; Robinson, L; Siervo, M; Stephan, BC; Teh, R; Wesnes, KA1
Cai, RW; Chen, YF; Huang, YH; Li, JJ; Li, MM; Lin, YY1
de Groot, RH; Durga, J; Jolles, J; Kok, FJ; Schiepers, OJ; van Boxtel, MP; Verhoef, P1
Ames, D; Bush, AI; Ellis, KA; Faux, NG; Fowler, CJ; Laws, SM; Martins, RN; Masters, CL; Pertile, KK; Porter, L; Rembach, A; Rowe, CC; Rumble, RL; Szoeke, C; Taddei, K; Taddei, T; Trounson, BO; Villemagne, VL; Ward, V1
Jagust, WJ; Lo, RY1
Brodaty, H; Crawford, J; Draper, B; Kang, K; Kochan, NA; Lipnicki, DM; Lux, O; Mather, KA; Reppermund, S; Sachdev, PS; Slavin, MJ; Trollor, JN1
Gustafson, L; Hultberg, B; Nilsson, K1
Eissa, AM; Hewedi, DH; Moustafa, AA; Myers, CE; Sadek, HA1

Reviews

14 review(s) available for homocysteine and Cognitive Dysfunction

ArticleYear
Hyperhomocysteinemia: Metabolic Role and Animal Studies with a Focus on Cognitive Performance and Decline-A Review.
    Biomolecules, 2021, 10-19, Volume: 11, Issue:10

    Topics: Animals; Cognition; Cognitive Dysfunction; Homocysteine; Humans; Hyperhomocysteinemia; One-Carbon Group Transferases

2021
Homocysteine levels, genetic background, and cognitive impairment in Parkinson's disease.
    Journal of neurology, 2023, Volume: 270, Issue:1

    Topics: Case-Control Studies; Cognitive Dysfunction; Folic Acid; Genetic Background; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Parkinson Disease; Vitamin B 12

2023
Features of Plasma Homocysteine, Vitamin B12, and Folate in Parkinson's Disease: An Updated Meta-Analysis.
    Journal of integrative neuroscience, 2023, Aug-14, Volume: 22, Issue:5

    Topics: Cognitive Dysfunction; Folic Acid; Homocysteine; Humans; Parkinson Disease; Vitamin B 12

2023
Homocysteine - from disease biomarker to disease prevention.
    Journal of internal medicine, 2021, Volume: 290, Issue:4

    Topics: Adult; Aged; Biomarkers; Child; Cognitive Dysfunction; Homocysteine; Humans; Macular Degeneration; Neural Tube Defects; Stroke; Vitamin B Complex

2021
Sleep disturbance in mild cognitive impairment: a systematic review of recent findings.
    Current opinion in psychiatry, 2018, Volume: 31, Issue:2

    Topics: Biomarkers; Brain; Circadian Clocks; Cognitive Dysfunction; Homocysteine; Humans; Orexins; Oxidative Stress; Risk Factors; Sleep; Sleep Wake Disorders

2018
Inborn Errors of Metabolism with Cognitive Impairment: Metabolism Defects of Phenylalanine, Homocysteine and Methionine, Purine and Pyrimidine, and Creatine.
    Pediatric clinics of North America, 2018, Volume: 65, Issue:2

    Topics: Cognitive Dysfunction; Creatine; Diagnosis, Differential; Homocysteine; Humans; Metabolism, Inborn Errors; Methionine; Phenylalanine; Purines; Pyrimidines

2018
Hyperhomocysteinemia and risk of incident cognitive outcomes: An updated dose-response meta-analysis of prospective cohort studies.
    Ageing research reviews, 2019, Volume: 51

    Topics: Alzheimer Disease; Cognition; Cognitive Dysfunction; Cohort Studies; Dementia, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Prospective Studies; Risk Factors

2019
Homocysteine: A modifiable culprit of cognitive impairment for us to conquer?
    Journal of the neurological sciences, 2019, Sep-15, Volume: 404

    Topics: Cognition Disorders; Cognitive Dysfunction; Homocysteine; Humans

2019
Vitamin B12 and cognitive function: an evidence-based analysis.
    Ontario health technology assessment series, 2013, Volume: 13, Issue:23

    Topics: Blood Chemical Analysis; Cognition; Cognitive Dysfunction; Dementia; Dietary Supplements; Evidence-Based Practice; Homocysteine; Humans; Injections, Intramuscular; Longitudinal Studies; Ontario; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2013
Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID).
    Biochimica et biophysica acta, 2016, Volume: 1862, Issue:5

    Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Disease Models, Animal; Homocysteine; Humans; Hyperhomocysteinemia

2016
Homocysteine and Mild Cognitive Impairment: Are These the Tools for Early Intervention in the Dementia Spectrum?
    The journal of nutrition, health & aging, 2016, Volume: 20, Issue:2

    Topics: Brain; Cognition; Cognitive Dysfunction; Dementia; Disease Progression; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex

2016
Homocysteine, B Vitamins, and Cognitive Impairment.
    Annual review of nutrition, 2016, 07-17, Volume: 36

    Topics: Aging; Animals; Biomarkers; Cerebrovascular Circulation; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nootropic Agents; Nutritional Status; Practice Guidelines as Topic; Risk Factors; Vitamin B 12; Vitamin B 6

2016
Cognitive decline: A vitamin B perspective.
    Maturitas, 2016, Volume: 93

    Topics: Cognition; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Homocysteine; Humans; Memory; Vitamin B Complex

2016
Predicting Risk of Cognitive Decline in Very Old Adults Using Three Models: The Framingham Stroke Risk Profile; the Cardiovascular Risk Factors, Aging, and Dementia Model; and Oxi-Inflammatory Biomarkers.
    Journal of the American Geriatrics Society, 2017, Volume: 65, Issue:2

    Topics: Aged, 80 and over; Biomarkers; C-Reactive Protein; Cognitive Dysfunction; Cohort Studies; Female; Homocysteine; Humans; Interleukin-6; Longitudinal Studies; Male; Proportional Hazards Models; Risk Assessment

2017

Trials

11 trial(s) available for homocysteine and Cognitive Dysfunction

ArticleYear
Omega-3 Supplementation for the Prevention of Cognitive Decline in Older Adults: Does It Depend on Homocysteine Levels?
    The journal of nutrition, health & aging, 2022, Volume: 26, Issue:6

    Topics: Aged; Cognition; Cognitive Dysfunction; Dietary Supplements; Fatty Acids, Omega-3; Homocysteine; Humans

2022
B Vitamin Supplementation Slows Cognitive Decline in Mild Cognitive Impairment Patients with Frontal Lobe Atrophy.
    Journal of Alzheimer's disease : JAD, 2022, Volume: 89, Issue:4

    Topics: Aspirin; Atrophy; Cognition; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Frontal Lobe; Homocysteine; Humans; Vitamin B 12; Vitamin B Complex

2022
Dietary intakes and biomarker patterns of folate, vitamin B
    Clinical epigenetics, 2019, 10-11, Volume: 11, Issue:1

    Topics: Aged; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Pyrophosphatases; Thioredoxin Reductase 1; Vitamin B 12; Vitamin B 6

2019
A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients.
    Clinical nutrition (Edinburgh, Scotland), 2020, Volume: 39, Issue:8

    Topics: Aged; Aged, 80 and over; Cognition; Cognitive Dysfunction; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Treatment Outcome; Vitamin B 12; Vitamin B Complex

2020
Vitamin D, homocysteine and n-3PUFA status according to physical and cognitive functions in older adults with subjective memory complaint: Results from cross-sectional study of the MAPT trial.
    Experimental gerontology, 2018, 10-01, Volume: 111

    Topics: Aged; Aged, 80 and over; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Fatty Acids, Omega-3; Female; Homocysteine; Humans; Logistic Models; Male; Memory; Vitamin D; Vitamin D Deficiency

2018
Multiple biomarkers covering several pathways improve predictive ability for cognitive impairment among ischemic stroke patients with elevated blood pressure.
    Atherosclerosis, 2019, Volume: 287

    Topics: Biomarkers; Blood Pressure; Brain Ischemia; China; Cognition; Cognitive Dysfunction; Female; Follow-Up Studies; Homocysteine; Humans; Incidence; Male; Matrix Metalloproteinase 9; Middle Aged; Neuropsychological Tests; Pilot Projects; Predictive Value of Tests; Prospective Studies; Rheumatoid Factor; Single-Blind Method; Time Factors

2019
B vitamin supplementation improves cognitive function in the middle aged and elderly with hyperhomocysteinemia.
    Nutritional neuroscience, 2016, Volume: 19, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; China; Cognitive Dysfunction; Dietary Supplements; Elder Nutritional Physiological Phenomena; Female; Folic Acid; Follow-Up Studies; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nursing Homes; Prevalence; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12; Vitamin B 6

2016
Effects of 6-Month Folic Acid Supplementation on Cognitive Function and Blood Biomarkers in Mild Cognitive Impairment: A Randomized Controlled Trial in China.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2016, Volume: 71, Issue:10

    Topics: Aged; Biomarkers; China; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Treatment Outcome; Vitamin B 12

2016
Vitamin B-12 concentration, memory performance, and hippocampal structure in patients with mild cognitive impairment.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:4

    Topics: Aged; Aged, 80 and over; Apolipoprotein E4; Cognition; Cognitive Dysfunction; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Genotyping Techniques; Hippocampus; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Memory; Middle Aged; Polymorphism, Single Nucleotide; Verbal Learning; Vitamin B 12

2016
A randomized placebo controlled trial of vitamin B
    Clinical nutrition (Edinburgh, Scotland), 2017, Volume: 36, Issue:6

    Topics: Aged; Cholesterol; Cognitive Dysfunction; Creatinine; Diabetes Mellitus; Dietary Supplements; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Neuropsychological Tests; Socioeconomic Factors; Triglycerides; Vitamin B 12

2017
DNA methylation and cognitive functioning in healthy older adults.
    The British journal of nutrition, 2012, Volume: 107, Issue:5

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Aging; Cognitive Dysfunction; Cross-Sectional Studies; Cytosine; DNA Methylation; Double-Blind Method; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Genetic Association Studies; Homocysteine; Humans; Leukocytes; Male; Middle Aged; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales

2012

Other Studies

93 other study(ies) available for homocysteine and Cognitive Dysfunction

ArticleYear
Association between plasma homocysteine levels and cognitive deficits in Han Chinese patients with schizophrenia across age groups.
    Scientific reports, 2021, 10-05, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Cognitive Dysfunction; Female; Homocysteine; Humans; Male; Middle Aged; Prognosis; Schizophrenia; Schizophrenic Psychology; Symptom Assessment; Young Adult

2021
The Link between Exercise and Homocysteine in the Alzheimer's Disease: A Bioinformatic Network Model.
    CNS & neurological disorders drug targets, 2021, Volume: 20, Issue:9

    Topics: Alzheimer Disease; Brain; Cognitive Dysfunction; Computational Biology; Exercise; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress

2021
Association of elevated blood homocysteine with cognitive decline in early, untreated Parkinson's disease.
    Journal of the neurological sciences, 2022, Mar-15, Volume: 434

    Topics: Cognitive Dysfunction; Disease Progression; Homocysteine; Humans; Parkinson Disease

2022
Influences of Vitamin B
    Nutrients, 2022, Apr-02, Volume: 14, Issue:7

    Topics: Aged; Aged, 80 and over; Atrophy; Cognition; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins

2022
Homocysteine-Induced Disturbances in DNA Methylation Contribute to Development of Stress-Associated Cognitive Decline in Rats.
    Neuroscience bulletin, 2022, Volume: 38, Issue:8

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; DNA Methylation; Homocysteine; Hyperhomocysteinemia; Rats; Stress, Psychological

2022
Response to letter: "Association of elevated blood homocysteine with cognitive decline in early, untreated Parkinson's disease".
    Journal of the neurological sciences, 2022, 07-15, Volume: 438

    Topics: Cognitive Dysfunction; Homocysteine; Humans; Neuropsychological Tests; Parkinson Disease

2022
Circulating folate concentrations and the risk of mild cognitive impairment: A prospective study on the older Chinese population without folic acid fortification.
    European journal of neurology, 2022, Volume: 29, Issue:10

    Topics: Aged; Apolipoprotein E4; China; Cognitive Dysfunction; Cohort Studies; Folic Acid; Homocysteine; Humans; Prospective Studies; Vitamin B 12

2022
Clinical characteristics of cognitive impairment and its related risk factors in post-stroke epilepsy
    Epileptic disorders : international epilepsy journal with videotape, 2022, 08-01, Volume: 24, Issue:4

    Topics: Adult; Anticonvulsants; Brain Ischemia; Cognitive Dysfunction; Epilepsy; Homocysteine; Humans; Risk Factors; Stroke

2022
Intrinsic Capacity Declines with Elevated Homocysteine in Community-Dwelling Chinese Older Adults.
    Clinical interventions in aging, 2022, Volume: 17

    Topics: Aged; China; Cognitive Dysfunction; Cross-Sectional Studies; Homocysteine; Humans; Independent Living

2022
Study of the value of homocysteine levels in predicting cognitive dysfunction in patients after acute carbon monoxide poisoning.
    BMC emergency medicine, 2022, 07-19, Volume: 22, Issue:1

    Topics: Carbon Monoxide Poisoning; Cognitive Dysfunction; Creatinine; Homocysteine; Humans; Retrospective Studies

2022
Gender differences in associations of cognitive impairments with homocysteine in schizophrenia.
    Asian journal of psychiatry, 2022, Volume: 75

    Topics: Cognitive Dysfunction; Homocysteine; Humans; Neuropsychological Tests; Schizophrenia; Sex Factors

2022
A Retrospective Study on Clinical Assessment of Cognitive Impairment in a Swedish Cohort: Is There Inequality Between Natives and Foreign-Born?
    Journal of Alzheimer's disease : JAD, 2022, Volume: 89, Issue:4

    Topics: Albumins; Alzheimer Disease; Atrophy; Biomarkers; Calcium; Cognitive Dysfunction; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Retrospective Studies; Sweden; Thyrotropin; Vitamin B 12

2022
One-Carbon Metabolism Biomarkers and Risks of Incident Neurocognitive Disorder among Cognitively Normal Older Adults.
    Nutrients, 2022, Aug-27, Volume: 14, Issue:17

    Topics: Aged; Biomarkers; Carbon; Cognitive Dysfunction; Dementia; Folic Acid; Homocysteine; Humans; Vitamin B 12

2022
Serum Homocysteine, Vitamin B12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia.
    Journal of Alzheimer's disease : JAD, 2022, Volume: 90, Issue:2

    Topics: Alzheimer Disease; Cognitive Dysfunction; Dementia, Vascular; Folic Acid; Frontotemporal Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12

2022
Association of homocysteine-related subcortical brain atrophy with white matter lesion volume and cognition in healthy aging.
    Neurobiology of aging, 2023, Volume: 121

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atrophy; Brain; Cognition; Cognitive Dysfunction; Healthy Aging; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; White Matter

2023
Homocysteine - A predictor for five year-mortality in patients with subjective cognitive decline, mild cognitive impairment and Alzheimer's dementia.
    Experimental gerontology, 2023, Volume: 172

    Topics: Alzheimer Disease; Cognition; Cognitive Dysfunction; Disease Progression; Homocysteine; Humans; Neuropsychological Tests; Retrospective Studies

2023
Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes.
    Journal of neuroinflammation, 2023, Sep-01, Volume: 20, Issue:1

    Topics: Alzheimer Disease; Animals; Atorvastatin; Cognition; Cognitive Dysfunction; Dementia, Vascular; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Mice

2023
Association of Leukocyte Telomere Length with Mild Cognitive Impairment and Alzheimer's Disease: Role of Folate and Homocysteine.
    Dementia and geriatric cognitive disorders, 2019, Volume: 48, Issue:1-2

    Topics: Aged; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Correlation of Data; Female; Folic Acid; Homocysteine; Humans; Leukocytes; Male; Middle Aged; Telomere Shortening

2019
Associations of C-reactive protein and homocysteine concentrations with the impairment of intrinsic capacity domains over a 5-year follow-up among community-dwelling older adults at risk of cognitive decline (MAPT Study).
    Experimental gerontology, 2019, Volume: 127

    Topics: Activities of Daily Living; Aged; Biomarkers; Body Mass Index; C-Reactive Protein; Cognitive Dysfunction; Depression; Female; Follow-Up Studies; Geriatric Assessment; Hand Strength; Homocysteine; Humans; Independent Living; Inflammation; Male; Mobility Limitation; Neuropsychological Tests; Prospective Studies; Risk Factors; Time Factors

2019
Plasma Apolipoprotein E Monomer and Dimer Profile and Relevance to Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 71, Issue:4

    Topics: Aged; Alzheimer Disease; Apolipoprotein A-II; Apolipoprotein E3; Apolipoprotein E4; Biomarkers; Cognitive Dysfunction; Female; Homocysteine; Homozygote; Humans; Male; Protein Structure, Quaternary; tau Proteins

2019
Association between serum homocysteine level and cognitive function in middle-aged type 2 diabetes mellitus patients.
    PloS one, 2019, Volume: 14, Issue:11

    Topics: Adult; Case-Control Studies; Cognitive Dysfunction; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Indonesia; Male; Middle Aged; Neuropsychological Tests; Risk Factors; Surveys and Questionnaires

2019
The relationship between cognitive impairment and homocysteine in a B12 and folate deficient population in China: A cross-sectional study.
    Medicine, 2019, Volume: 98, Issue:47

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; China; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency

2019
The Different Relationship between Homocysteine and Uric Acid Levels with Respect to the MTHFR C677T Polymorphism According to Gender in Patients with Cognitive Impairment.
    Nutrients, 2020, Apr-19, Volume: 12, Issue:4

    Topics: Aged; Aged, 80 and over; Biomarkers; Cerebrovascular Disorders; Cognitive Dysfunction; Female; Genetic Association Studies; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Retrospective Studies; Sex Characteristics; Uric Acid

2020
Hydrogen Sulfide Alleviates Anxiety, Motor, and Cognitive Dysfunctions in Rats with Maternal Hyperhomocysteinemia via Mitigation of Oxidative Stress.
    Biomolecules, 2020, 07-02, Volume: 10, Issue:7

    Topics: Animals; Anxiety; Cognitive Dysfunction; Cystathionine beta-Synthase; Female; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Oxidative Stress; Pregnancy; Pregnancy Complications; Rats; Reactive Oxygen Species; Treatment Outcome

2020
Homocysteic Acid in Blood Can Detect Mild Cognitive Impairment: A Preliminary Study.
    Journal of Alzheimer's disease : JAD, 2020, Volume: 77, Issue:2

    Topics: Aged; Aged, 80 and over; Biomarkers; Cognitive Dysfunction; Female; Homocysteine; Humans; Male; Middle Aged

2020
Interactive effects of elevated homocysteine and late-life depression on cognitive impairment.
    Journal of affective disorders, 2020, 12-01, Volume: 277

    Topics: Aged; Cognition; Cognitive Dysfunction; Depression; Homocysteine; Humans; Neuropsychological Tests

2020
Homocysteinemia is Associated with the Presence of Microbleeds in Cognitively Impaired Patients.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:12

    Topics: Aged; Aged, 80 and over; Biomarkers; Cerebral Hemorrhage; Cognition; Cognitive Dysfunction; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Risk Factors; Seoul

2020
Adolescent/adult-onset homocysteine remethylation disorders characterized by gait disturbance with/without psychiatric symptoms and cognitive decline: a series of seven cases.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Cognitive Dysfunction; Gait Disorders, Neurologic; Homocysteine; Homocystinuria; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2021
The effect of folate and VitB
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 81

    Topics: Aged; Cognition; Cognitive Dysfunction; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Treatment Outcome; Vitamin B 12

2020
Homocysteine is Associated with the Development of Cerebral Small Vessel Disease: Retrospective Analyses from Neuroimaging and Cognitive Outcomes.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:12

    Topics: Aged; Biomarkers; Cerebral Small Vessel Diseases; Cognition; Cognitive Dysfunction; Female; Homocysteine; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Mental Status and Dementia Tests; Middle Aged; Neuroimaging; Predictive Value of Tests; Prognosis; Registries; Retrospective Studies; Risk Assessment; Risk Factors

2020
Levels of Vitamins and Homocysteine in Older Adults with Alzheimer Disease or Mild Cognitive Impairment in Cuba.
    MEDICC review, 2020, Volume: 22, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognitive Dysfunction; Cross-Sectional Studies; Cuba; Homocysteine; Humans; Vitamins

2020
Hyperhomocysteinemia and Dementia Associated With Severe Cortical Atrophy, but No Amyloid Burden.
    Journal of geriatric psychiatry and neurology, 2022, Volume: 35, Issue:1

    Topics: Aged; Alzheimer Disease; Atrophy; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia

2022
Interactions Between Handgrip Strength and Serum Folate and Homocysteine Levels on Cognitive Function in the Elderly Chinese Population.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 80, Issue:4

    Topics: Aged; Aged, 80 and over; China; Cognition; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Hand Strength; Homocysteine; Humans; Linear Models; Male; Mental Status and Dementia Tests; Middle Aged

2021
Synergistic Effect of Serum Homocysteine and Diabetes Mellitus on Brain Alterations.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 81, Issue:1

    Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Atrophy; Brain; Cognitive Dysfunction; Diabetes Mellitus; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Neuropsychological Tests; Positron-Emission Tomography; tau Proteins

2021
Relationship of Homocysteine Plasma Levels with Mild Cognitive Impairment, Alzheimer's Disease, Vascular Dementia, Psychobehavioral, and Functional Complications.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 82, Issue:1

    Topics: Activities of Daily Living; Aged; Alzheimer Disease; Brief Psychiatric Rating Scale; Cognitive Dysfunction; Dementia, Vascular; Female; Homocysteine; Humans; Interviews as Topic; Male

2021
Cross-Sectional Examination of Homocysteine Levels with Sarcopenia and Its Components in Memory Clinic Outpatients.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 82, Issue:3

    Topics: Aged; Aged, 80 and over; Biomarkers; Cognitive Dysfunction; Cross-Sectional Studies; Female; Hand Strength; Homocysteine; Humans; Male; Outpatient Clinics, Hospital; Outpatients; Sarcopenia

2021
Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children.
    The American journal of clinical nutrition, 2017, Volume: 105, Issue:5

    Topics: Adult; Asia; Child Development; Cognition; Cognitive Dysfunction; Female; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Nepal; Neurodevelopmental Disorders; Neuropsychological Tests; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2017
Hydrogen sulfide attenuates homocysteine-induced cognitive deficits and neurochemical alterations by improving endogenous hydrogen sulfide levels.
    BioFactors (Oxford, England), 2017, May-06, Volume: 43, Issue:3

    Topics: Animals; Cerebral Cortex; Cognition; Cognitive Dysfunction; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dopamine; Epinephrine; Gene Expression; Hippocampus; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Injections, Subcutaneous; Locomotion; Male; Maze Learning; Monoamine Oxidase; Norepinephrine; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Serotonin; Sulfides

2017
Can Nutrition or Inflammation Moderate the Age-Cognition Association Among Older Adults?
    The journals of gerontology. Series B, Psychological sciences and social sciences, 2019, 01-10, Volume: 74, Issue:2

    Topics: Age Factors; Aged; beta Carotene; Biomarkers; C-Reactive Protein; Cognition; Cognitive Dysfunction; Diet; Female; Ferritins; Fibrinogen; Folic Acid; Homocysteine; Humans; Inflammation; Iron; Male; Middle Aged; Neuropsychological Tests; Nutrition Surveys; Nutritional Status; Vitamins

2019
Diagnostic Values of Serum Levels of Homocysteine and Uric Acid for Predicting Vascular Mild Cognitive Impairment in Patients with Cerebral Small Vessel Disease.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, May-10, Volume: 23

    Topics: Aged; Case-Control Studies; Cerebral Small Vessel Diseases; Cholesterol; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; ROC Curve; Uric Acid; Vitamin B 12

2017
Increased Plasma Homocysteine Level is Associated with Executive Dysfunction in Type 2 Diabetic Patients with Mild Cognitive Impairment.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 58, Issue:4

    Topics: Cognitive Dysfunction; Cystathionine beta-Synthase; Diabetes Mellitus, Type 2; Executive Function; Female; Gene Frequency; Genotype; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Neuropsychological Tests; Polymorphism, Single Nucleotide; Severity of Illness Index

2017
Toxoplasma Gondii Moderates the Association between Multiple Folate-Cycle Factors and Cognitive Function in U.S. Adults.
    Nutrients, 2017, Jun-02, Volume: 9, Issue:6

    Topics: Adult; Biomarkers; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutrition Surveys; Sample Size; Socioeconomic Factors; Toxoplasma; Toxoplasmosis; Vitamin B 12; Young Adult

2017
One-Carbon Metabolism Biomarkers and Cognitive Decline in the Very Old: The Newcastle 85+ Study.
    Journal of the American Medical Directors Association, 2017, Sep-01, Volume: 18, Issue:9

    Topics: Aged, 80 and over; Biomarkers; Cognitive Dysfunction; England; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Prospective Studies; Vitamin B 12

2017
Plasma homocysteine and cerebral small vessel disease as possible mediators between kidney and cognitive functions in patients with diabetes mellitus.
    Scientific reports, 2017, 06-29, Volume: 7, Issue:1

    Topics: Aged; Aged, 80 and over; Biomarkers; Cerebral Small Vessel Diseases; Cognition; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Homocysteine; Humans; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Odds Ratio; Prognosis

2017
Plasma Homocysteine and Serum Folate and Vitamin B
    Nutrients, 2017, Jul-08, Volume: 9, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12

2017
Sleep mediates the association between homocysteine and oxidative status in mild cognitive impairment.
    Scientific reports, 2017, 08-10, Volume: 7, Issue:1

    Topics: Aged; Biomarkers; Brain Mapping; Cerebral Cortex; Cognition; Cognitive Dysfunction; Disease Susceptibility; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Oxidative Stress; Sleep

2017
Homocysteine and cognitive function in Parkinson's disease.
    Parkinsonism & related disorders, 2017, Volume: 44

    Topics: Aged; Antiparkinson Agents; Cognition; Cognitive Dysfunction; Cohort Studies; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease

2017
Homocysteine, Tryptophan, and Cognition in the Very Old.
    Journal of the American Medical Directors Association, 2017, 10-01, Volume: 18, Issue:10

    Topics: Aged; Cognition; Cognitive Dysfunction; Homocysteine; Humans; Tryptophan

2017
Homocysteine Biochemistry and Cognitive Decline in the Elderly.
    Journal of the American Medical Directors Association, 2017, 10-01, Volume: 18, Issue:10

    Topics: Aged; Biomarkers; Carbon; Cognitive Dysfunction; Homocysteine; Humans; Vitamin B 12

2017
Vitamin Status and the Development of Postoperative Cognitive Decline in Elderly Surgical Oncologic Patients.
    Annals of surgical oncology, 2018, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Preoperative Period; Vitamin B 12

2018
Genetic influence of plasma homocysteine on Alzheimer's disease.
    Neurobiology of aging, 2018, Volume: 62

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Atrophy; Cognitive Dysfunction; Female; Genetic Association Studies; Genetic Predisposition to Disease; Gray Matter; Homocysteine; Humans; Male; Multifactorial Inheritance; Risk Factors; tau Proteins; White People

2018
Gender differences in C-reactive protein and homocysteine modulation of cognitive performance and real-world functioning in bipolar disorder.
    Journal of affective disorders, 2018, 03-15, Volume: 229

    Topics: Adult; Bipolar Disorder; C-Reactive Protein; Cognition; Cognitive Dysfunction; Female; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Sex Factors

2018
Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.
    Behavioural brain research, 2018, 04-16, Volume: 342

    Topics: Animals; Cognitive Dysfunction; Endoplasmic Reticulum Stress; Hippocampus; Homocysteine; Hydrogen Sulfide; Male; Memory; Rats; Rats, Sprague-Dawley; Sirtuin 1; Temporal Lobe; Up-Regulation

2018
Cognitive impairment is associated with elevated serum homocysteine levels among older adults.
    European journal of nutrition, 2019, Volume: 58, Issue:1

    Topics: Aged; Causality; Cognitive Dysfunction; Cohort Studies; Comorbidity; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Prevalence; Republic of Korea; Vitamin B 12

2019
Correlation study of Framingham risk score and vascular dementia: An observational study.
    Medicine, 2017, Volume: 96, Issue:50

    Topics: Age Factors; Aged; Aged, 80 and over; Blood Pressure; Case-Control Studies; Cholesterol; Cognitive Dysfunction; Dementia, Vascular; Female; Glycated Hemoglobin; Homocysteine; Humans; Linear Models; Magnetic Resonance Imaging; Male; Mental Status and Dementia Tests; Middle Aged; Prognosis; Risk Assessment; White Matter

2017
Low-grade systemic inflammation is associated with functional disability in elderly people affected by dementia.
    GeroScience, 2018, Volume: 40, Issue:1

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; C-Reactive Protein; Case-Control Studies; Cognitive Dysfunction; Dementia; Disability Evaluation; Disease Progression; Female; Geriatric Assessment; Homocysteine; Humans; Inflammation; Italy; Male; Reference Values; Retrospective Studies

2018
Homocysteine and Dementia: An International Consensus Statement.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 62, Issue:2

    Topics: Cognition; Cognitive Dysfunction; Consensus; Dementia; Dietary Supplements; Homocysteine; Humans; Meta-Analysis as Topic; Review Literature as Topic; Risk Factors; Vitamin B Complex

2018
Exercise Mitigates Alcohol Induced Endoplasmic Reticulum Stress Mediated Cognitive Impairment through ATF6-Herp Signaling.
    Scientific reports, 2018, 03-26, Volume: 8, Issue:1

    Topics: Activating Transcription Factor 6; Analysis of Variance; Animals; Behavior, Animal; Blood Pressure; Blood-Brain Barrier; Capillary Permeability; Cerebrovascular Circulation; Cognitive Dysfunction; Endoplasmic Reticulum Stress; Epigenesis, Genetic; Ethanol; Exercise Test; Exercise Therapy; Homocysteine; Hyperhomocysteinemia; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Animal; Normal Distribution; Oxidative Stress; Physical Conditioning, Animal

2018
Time-response studies on development of cognitive deficits in an experimental model of insulin resistance.
    Clinical nutrition (Edinburgh, Scotland), 2019, Volume: 38, Issue:3

    Topics: Animals; Biomarkers; Blood Glucose; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Fructose; Homocysteine; Insulin; Insulin Resistance; Male; Oxidative Stress; Rats; Rats, Wistar; Time Factors

2019
Small Vessel Cerebrovascular Pathology Identified by Magnetic Resonance Imaging Is Prevalent in Alzheimer's Disease and Mild Cognitive Impairment: A Potential Target for Intervention.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 65, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain Infarction; Cerebrovascular Disorders; Cognitive Dysfunction; Cross-Sectional Studies; Disease Progression; Female; Homocysteine; Humans; Image Processing, Computer-Assisted; Independent Living; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Risk Factors

2018
Chronic folate deficiency induces glucose and lipid metabolism disorders and subsequent cognitive dysfunction in mice.
    PloS one, 2018, Volume: 13, Issue:8

    Topics: Animals; Cognition; Cognitive Dysfunction; Diet; Female; Folic Acid; Folic Acid Deficiency; Glucose; Homocysteine; Insulin Resistance; Lipid Metabolism; Mice; Mice, Inbred ICR; Time Factors

2018
Association of vitamin B12 mediated hyperhomocysteinemia and methylenetetrafolate reductase (C677T) gene polymorphism with cognitive impairment: A population based study from North India.
    Psychiatry research, 2018, Volume: 270

    Topics: Adult; Aged; Cognitive Dysfunction; Comorbidity; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Vitamin B 12

2018
Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway.
    Neurobiology of disease, 2019, Volume: 121

    Topics: Animals; Cognitive Dysfunction; Dentate Gyrus; Entorhinal Cortex; Homocysteine; Hyperalgesia; Long-Term Potentiation; Mice, Inbred C57BL; Neural Pathways; Neuralgia; Neurons; Peripheral Nerve Injuries; Post-Synaptic Density; Receptors, AMPA; Sciatic Nerve

2019
Genetic influence of plasma homocysteine on Alzheimer's disease.
    Neurobiology of aging, 2019, Volume: 76

    Topics: Alzheimer Disease; Cognitive Dysfunction; Genetic Association Studies; Homocysteine; Humans

2019
Hypermethylation of ERа-A gene and high serum homocysteine level are correlated with cognitive impairment in white matter hyperintensity patients.
    QJM : monthly journal of the Association of Physicians, 2019, May-01, Volume: 112, Issue:5

    Topics: Activities of Daily Living; Aged; Cognition; Cognitive Dysfunction; CpG Islands; DNA Methylation; Estrogen Receptor alpha; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Mental Status and Dementia Tests; Middle Aged; Regression Analysis; White Matter

2019
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study.
    Journal of the American Medical Directors Association, 2019, Volume: 20, Issue:5

    Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Homocysteine; Humans; Ireland; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B Complex

2019
Interaction of nutrition and genetics via DNMT3L-mediated DNA methylation determines cognitive decline.
    Neurobiology of aging, 2019, Volume: 78

    Topics: Aged; Aged, 80 and over; Atrophy; Brain; Cognition; Cognitive Dysfunction; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Homocysteine; Humans; Male; S-Adenosylmethionine; Spatial Memory; Vitamin B Complex

2019
Urate and Homocysteine: Predicting Motor and Cognitive Changes in Newly Diagnosed Parkinson's Disease.
    Journal of Parkinson's disease, 2019, Volume: 9, Issue:2

    Topics: Aged; Case-Control Studies; Cognitive Dysfunction; Disease Progression; Female; Follow-Up Studies; Homocysteine; Humans; Linear Models; Male; Mental Status and Dementia Tests; Middle Aged; Parkinson Disease; Prognosis; Prospective Studies; Uric Acid

2019
Homocysteine, rather than age of onset, is a better predictor for cognitive function in older adults with bipolar disorder.
    International journal of geriatric psychiatry, 2019, Volume: 34, Issue:10

    Topics: Age of Onset; Aged; Attention; Biomarkers; Bipolar Disorder; Cognition; Cognitive Dysfunction; Diagnostic and Statistical Manual of Mental Disorders; Executive Function; Female; Homocysteine; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Psychomotor Performance

2019
Association Between Cognitive Impairment and Vitamin B12, Folate, and Homocysteine Status in Elderly Adults: A Retrospective Study.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 70, Issue:2

    Topics: Aged; Aged, 80 and over; Biomarkers; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency

2019
Evaluation of hyperhomocysteinemia prevalence and its influence on the selected cognitive functions in patients with schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2019, 12-20, Volume: 95

    Topics: Adult; Cognition; Cognitive Dysfunction; Comorbidity; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neuropsychological Tests; Prevalence; Schizophrenia; Schizophrenic Psychology

2019
Relationship between folate, vitamin B
    International journal of food sciences and nutrition, 2020, Volume: 71, Issue:3

    Topics: Aged; Case-Control Studies; China; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Transaminases; Vitamin B 12

2020
Oxidative balance, homocysteine, and uric acid levels in older patients with Late Onset Alzheimer's Disease or Vascular Dementia.
    Journal of the neurological sciences, 2014, Feb-15, Volume: 337, Issue:1-2

    Topics: Advanced Oxidation Protein Products; Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cognitive Dysfunction; Dementia, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Hydrogen Peroxide; Male; Neuropsychological Tests; Oxidative Stress; Retrospective Studies; Tomography, X-Ray Computed; Uric Acid

2014
Association of homocysteine with hippocampal volume independent of cerebral amyloid and vascular burden.
    Neurobiology of aging, 2014, Volume: 35, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cognition Disorders; Cognitive Dysfunction; Female; Hippocampus; Homocysteine; Humans; Linear Models; Male; Middle Aged; Risk Factors

2014
Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals.
    The American journal of clinical nutrition, 2014, Volume: 100, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Randomized Controlled Trials as Topic; Vitamin B Complex

2014
Domain specific changes in cognition at high altitude and its correlation with hyperhomocysteinemia.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Acclimatization; Adult; Altitude; Cognition; Cognitive Dysfunction; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Neuropsychological Tests; Vitamin B 12

2014
Correlation of homocysteine metabolic enzymes gene polymorphism and mild cognitive impairment in the Xinjiang Uygur population.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Jan-27, Volume: 21

    Topics: Aged; Case-Control Studies; China; Cognitive Dysfunction; DNA Primers; Electrophoresis, Capillary; Female; Homocysteine; Homozygote; Humans; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic

2015
B-vitamin trials meta-analysis: less than meets the eye.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:2

    Topics: Aging; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex

2015
Homocysteine lowering, B vitamins, and cognitive aging.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:2

    Topics: Aging; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex

2015
Reply to Garrard and Jacoby and Smith et al.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:2

    Topics: Aging; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex

2015
Association between subclinical carotid atherosclerosis, hyperhomocysteinaemia and mild cognitive impairment.
    Acta neurologica Scandinavica, 2016, Volume: 134, Issue:2

    Topics: Aged; Aged, 80 and over; Carotid Artery Diseases; Carotid Intima-Media Thickness; Case-Control Studies; Cognitive Dysfunction; Female; Homocysteine; Humans; Male

2016
Association of homocysteine level and vascular burden and cognitive function in middle-aged and older adults with chronic kidney disease.
    International journal of geriatric psychiatry, 2016, Volume: 31, Issue:7

    Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Cognition; Cognition Disorders; Cognitive Dysfunction; Executive Function; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Renal Insufficiency, Chronic; Risk Factors; Vascular Diseases

2016
Effects of Multivitamin Supplements on Cognitive Function, Serum Homocysteine Level, and Depression of Korean Older Adults With Mild Cognitive Impairment in Care Facilities.
    Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing, 2016, Volume: 48, Issue:3

    Topics: Aged; Cognitive Dysfunction; Depression; Dietary Supplements; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Republic of Korea; Residential Facilities; Treatment Outcome; Vitamin B 12; Vitamin B 6

2016
Conversion from MCI to AD in patients with the APOE ε4 genotype: Prediction by plasma HCY and serum BDNF.
    Neuroscience letters, 2016, 07-28, Volume: 626

    Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Biomarkers; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Disease Progression; Female; Genotype; Homocysteine; Humans; Male; Sensitivity and Specificity

2016
The involvement of homocysteine in stress-induced Aβ precursor protein misprocessing and related cognitive decline in rats.
    Cell stress & chaperones, 2016, Volume: 21, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Hippocampus; Homocysteine; Male; Protein Processing, Post-Translational; Rats, Sprague-Dawley; Stress, Psychological

2016
Food Insecurity Is Associated with Subsequent Cognitive Decline in the Boston Puerto Rican Health Study.
    The Journal of nutrition, 2016, Volume: 146, Issue:9

    Topics: Acculturation; Adult; Aged; Apolipoproteins E; Body Mass Index; Boston; Cognition; Cognitive Dysfunction; Diet, Healthy; Exercise; Female; Follow-Up Studies; Food Supply; Homocysteine; Humans; Logistic Models; Longitudinal Studies; Male; Middle Aged; Nutrition Assessment; Puerto Rico; Socioeconomic Factors

2016
Homocysteine and Real-Space Navigation Performance among Non-Demented Older Adults.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 55, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Auditory Perception; Case-Control Studies; Cognitive Dysfunction; Discrimination, Psychological; Female; Homocysteine; Humans; Male; Maze Learning; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Spatial Navigation

2017
The association of uric acid with leukoaraiosis.
    The Journal of international medical research, 2017, Volume: 45, Issue:1

    Topics: Aged; Aged, 80 and over; Alcohol Drinking; Asian People; Cognitive Dysfunction; Cross-Sectional Studies; Diabetes Mellitus; Dizziness; Dyslipidemias; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Headache; Homocysteine; Humans; Hypertension; Hyperuricemia; Leukoaraiosis; Male; Middle Aged; Multivariate Analysis; Risk Factors; Smoking; Uric Acid

2017
Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study.
    Journal of Alzheimer's disease : JAD, 2011, Volume: 27, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; Australia; Brain; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Vitamin B 12

2011
Predicting missing biomarker data in a longitudinal study of Alzheimer disease.
    Neurology, 2012, May-01, Volume: 78, Issue:18

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognitive Dysfunction; Cohort Studies; Dementia, Vascular; Fluorodeoxyglucose F18; Homocysteine; Humans; Logistic Models; Longitudinal Studies; Magnetic Resonance Imaging; Neuropsychological Tests; Patient Dropouts; Peptide Fragments; Positron-Emission Tomography; Research Design; Risk Factors; tau Proteins

2012
Risk profiles for mild cognitive impairment vary by age and sex: the Sydney Memory and Ageing study.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2012, Volume: 20, Issue:10

    Topics: Age Factors; Aged; Aged, 80 and over; Apolipoprotein E4; Australia; Cognitive Dysfunction; Cross-Sectional Studies; Depression; Female; Heart Diseases; Homocysteine; Humans; Male; Neuropsychological Tests; Olfactory Perception; Prevalence; Residence Characteristics; Risk Factors; Sex Characteristics; Visual Acuity; Walking

2012
Elevated plasma homocysteine level is not primarily related to Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2012, Volume: 34, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency

2012
The relationship between associative learning, transfer generalization, and homocysteine levels in mild cognitive impairment.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Aged; Association Learning; Case-Control Studies; Cognitive Dysfunction; Female; Generalization, Psychological; Homocysteine; Humans; Male; Middle Aged; Transfer, Psychology

2012