homocysteine and Cognition Disorders

homocysteine has been researched along with Cognition Disorders in 242 studies

Research

Studies (242)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (1.65)18.2507
2000's120 (49.59)29.6817
2010's115 (47.52)24.3611
2020's3 (1.24)2.80

Authors

AuthorsStudies
Feng, Y; Huang, Y; Li, H; Li, Z; Wu, F; Wu, K; Xiong, X; Zhu, Z1
Ars, CL; Hofman, A; Jaddoe, VW; Marroun, HE; Muetzel, R; Nijs, IM; Schmidt, M; Steegers, EA; Steenweg-de Graaff, J; Tiemeier, H; van der Lugt, A; Verhulst, FC; White, T1
Laganà, AS; Rizzo, G1
Chen, XF; Ding, CW; Fu, XY; Liu, CF; Mao, CJ; Mao, P; Sheng, YJ; Song, X; Wang, CS; Yang, M; Zhang, Y; Zhang, YC1
Bowman, GL; Collino, S; Corthésy, J; Da Silva, L; Dayon, L; Descombes, P; Guiraud, SP; Henry, H; Kussmann, M; Marquis, J; Martin, FJ; Métairon, S; Migliavacca, E; Montoliu, I; Moullet, B; Oikonomidi, A; Popp, J; Tautvydaitė, D; Wojcik, J1
Andréasson, M; Brodin, L; Laffita-Mesa, JM; Svenningsson, P1
Alajbegović, L; Alajbegović, S; Avdagić, N; Babić, N; Dervišević, A; Hadžović-Džuvo, A; Lepara, O; Mutevelić-Turković, A; Valjevac, A; Zaćiragić, A1
Jacques, PF; Livingston, K; Rogers, G; Rosenberg, IH; Scott, TM; Selhub, J; Troen, AM; Weiner, DE1
Abdelalim, AM; Elfayoumy, NM; Elshebawy, H; Fahmy, EM; Ismail, RS; Sharaf, SA1
Auinger, P; Christine, CW; Green, R; Joslin, A; Yelpaala, Y1
Bulut, HT; Dayan, E; Tak, AZA1
Bao, J; Chen, D; Huang, F; Ke, D; Liu, R; Mahaman, YAR; Salissou, MTM; Wang, JZ; Wang, Q; Wang, X; Wang, Y; Wei, Z; Wu, M; Zhang, B1
Barhwal, K; Das, SK; Dhar, P; Hota, SK; Norboo, T; Sharma, VK; Singh, SB1
Cole, PD; Gulinello, ME; Maxwell, RR; Spira, M; Wen, J; Wolf, AJ1
Bo, F; Chen, H; Chen, YC; Geng, W; Jiang, L; Mao, CN; Yin, X; Zhang, H1
Chen, H; Cui, G; Dong, L; Hua, F; Jing, J; Li, H; Li, Y; Raza, HK; Ye, X; Zhang, Z1
Downey, LA; Ford, TC; McPhee, G; Oliver, C; Simpson, T; Stough, C1
Di Martino, G; Di Nicola, M; Falasca, K; Occhionero, A; Ucciferri, C; Vecchiet, J; Vignale, F1
Almeida, OP; Ford, AH2
Dong, Y; Ji, Y; Jin, W; Li, X; Lyu, P1
Solomon, LR1
Chang, AY; Chang, CC; Chang, WN; Chang, YT; Chen, NC; Huang, CW; Huang, SH; Lee, CC; Lui, CC1
Cheng, DM; Huang, CY; Jiang, YG; Kong, HY; Liu, J; Pang, W; Sun, SD1
Almeida, OP; Chen, C; Eikelboom, JW; Ford, AH; Gommans, J; Hankey, GJ; Lees, KR; Navarro, JC; Ranawaka, UK; Ricci, S; Schmidt, R; Uddin, W; van Bockxmeer, FM; Xavier, D; Yi, Q1
Abo-Krysha, N; Allam, M; Amer, H; El-Sawy, E; Elatti, SA; Fahmy, E1
Almeida, OP; Flicker, L; Ford, AH; Hirani, V; Singh, U1
Alibrandi, A; Caccamo, D; Di Rosa, G; Germanò, E; Guerrera, S; Lenzo, P; Neri, M; Nicotera, A; Parisi, E; Spanò, M; Tortorella, G1
de Groot, LC; Doets, EL; Eussen, SJ; Nurk, E; Nygård, OK; Refsum, H; Smith, AD; Tell, GS; Ueland, PM; Van't Veer, P; Vollset, SE1
Byun, MS; Choe, YM; Choi, HJ; Han, JY; Kim, YK; Lee, DY; Lee, JM; Park, J; Seo, EH; Sohn, BK; Woo, JI; Yoon, EJ1
Barrero, C; Chu, J; Li, JG; Merali, S; Praticò, D1
Chen, X; Hao, Y; Li, X; Li, Y; Lü, L; Song, X; Zhang, W; Zhu, Q1
de Jager, CA1
Beydoun, HA; Beydoun, MA; Gamaldo, AA; Teel, A; Wang, Y; Zonderman, AB1
Baierle, M; Bordignon, S; Breusing, N; Duarte, MM; Emanuelli, T; Garcia, SC; Grune, T; Oldenburg, L; Somacal, S; Trentini, CM; Veit, JC; Vencato, PH; Zibetti, M1
Chen, Y; Ding, C; Ge, J; Jia, X; Jiang, B; Qiu, E; Yao, C; Yao, G; Zhang, Y; Zhao, H1
Chang, N; Jang, W; Kim, G; Kim, H; Kim, SY1
Chen, H; Huang, G; Ji, L; Ji, Y; Liu, S; Ma, F; Wu, T; Zhang, M; Zheng, M; Zhou, Y1
Boehm-Sturm, P; Dirnagl, U; Farr, TD; Foddis, M; Füchtemeier, M; Harms, C; Jadavji, NM; Khalil, AA; Lips, J1
Bojar, I; Filip, R; Loroch, M; Owoc, A; Raszewski, G; Łukawski, K1
Elshorbagy, AK; Jernerén, F; Oulhaj, A; Refsum, H; Smith, AD; Smith, SM1
Harris, E; Macpherson, H; Pipingas, A1
Bonetti, F; Brombo, G; Magon, S; Zuliani, G1
Fujita, A; Kanouchi, H; Miyazaki, Y; Sugimoto, Y1
Atienza, M; Cantero, JL; Llado-Saz, S1
Krause, D; Roupas, P1
McCaddon, A; Miller, JW1
Chen, WW; Cheng, X; Huang, WJ; Sun, HQ; Xie, ZY; Zhang, QS; Zhang, X1
Chen, CS; Hsiao, SM; Huang, MF; Hwang, SJ; Kuo, MC; Liu, TL; Tsai, JC; Yang, YH; Yeh, YC1
Abbondanza, S; Davin, A; Guaita, A; Mangieri, M; Polito, L; Poloni, TE; Vaccaro, R; Villani, S1
Chwedorowicz, A; Chwedorowicz, R; Gustaw Rothenberg, K; Raszewski, G1
Benejam, B; Blanco-Hinojo, L; Bléhaut, H; Catuara-Solarz, S; Cuenca-Royo, A; de la Torre, R; de Sola, S; Del Hoyo, L; Delabar, JM; Dierssen, M; Dueñas-Espín, I; Espadaler, JM; Farré, M; Fitó, M; Hernandez, G; Janel, N; Langohr, K; Principe, A; Pujol, J; Rodriguez, J; Sanchez-Benavides, G; Videla, S; Xicota, L1
Refsum, H; Smith, AD1
Ayesa-Arriola, R; Crespo-Facorro, B; Setién-Suero, E; Suárez-Pinilla, M; Suárez-Pinilla, P1
Apostolopoulos, V; Bosevski, M; Mikkelsen, K; Stojanovska, L; Tangalakis, K1
Hasegawa, T; Ukai, W1
Asadollahi, K; Behzadi, S; Dastjerdi, MM; Ghahnavieh, AA; Hafezi Ahmadi, MR; Hatefi, M; Mahdizadeh, F; Rahmani, A1
Feng, H; Peng, S; Xiao, J; Xie, Y; Zhang, J1
Gu, HF; Li, M; Li, MH; Li, X; Tang, XQ; Wei, HJ; Zhang, P; Zou, W1
Nichols, J1
Cui, XP; Mu, JS; Ye, JX; Zhang, DM1
Abdollahnia, N; Hanemann, A; Hengstermann, S; Lämmler, G; Lun, A; Nieczaj, R; Schulz, RJ; Schweter, A; Steinhagen-Thiessen, E1
Andreazza, AC; Brissos, S; Cardoso, C; Dias, VV; Kapczinski, F1
Fuchs, D; Greilberger, J; Greilberger, M; Koidl, C; Lamprecht, M; Leblhuber, F; Oettl, K; Schroecksnadel, K1
Carrasco, M; Castro, C; Estrada, C; López-Toledano, MA; Murillo-Carretero, M; Rabaneda, LG; Ruiz, FA1
Enoki, H; Iguchi, A; Izawa, S; Kanda, S; Koike, T; Kuzuya, M; Okada, K1
Gustafson, L; Hultberg, B; Nilsson, K8
Aisen, PS; Bottiglieri, T; Diaz-Arrastia, R; Jin, S; Sano, M; Schneider, LS; Stokes, KT; Thal, LJ; Thomas, RG; van Dyck, CH; Weiner, MF1
Bennett, DA; Clarke, RJ1
Breteler, MM; de Lau, LM; Johnston, C; Refsum, H; Smith, AD1
Comijs, HC; Deeg, DJ; Dik, MG; Jonker, C; van den Kommer, TN1
Donaldson, MG; Liu-Ambrose, T1
Belén Sánchez-Saudinós, M; Blanco-Vaca, F; Blesa, R; Clarimón, J; Gich, I; Gómez-Isla, T; Lázaro, E; Lleó, A; Molina-Porcel, L; Sala, I1
Albert, CM; Buring, JE; Cook, N; Grodstein, F; Kang, JH; Manson, J1
Green, R; Luchsinger, JA; Miller, J; Reitz, C; Tang, MX1
Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J2
Hanemann, A; Hengstermann, S; Laemmler, G; Lun, A; Schulz, RJ; Schweter, A; Steinhagen-Thiessen, E1
Fang, H; Huang, C; Jiang, Y; Kong, H1
Bednarska-Makaruk, M; Bochyńska, A; Graban, A; Lipczyńska-Łojkowska, W; Rodo, M; Ryglewicz, D; Wehr, H1
Ochudło, S; Opala, G; Siuda, J; Targosz-Gajniak, M1
Pratico, D1
Machanic, BI1
Altamura, C; Bressi, F; Chiovenda, P; Curcio, G; Gorgone, G; Ientile, R; Pisani, F; Rossini, PM; Silvestrini, M; Squitti, R; Tombini, M; Ursini, F; Vernieri, F1
Bescos, E; Clavero, P; García-Garcia, D; Irigoien, J; Irurzun, C; Kulisevsky, J; Lage, PM; Lamet, I; Matsubara, JM; Obeso, JA; Pagonabarraga, J; Pérez-Tur, J; Rodriguez-Oroz, MC; Samaranch, L; Sanchez-Mut, J; Toledo, JB1
Beaumont, H; Jacoby, R; King, E; Oulhaj, A; Refsum, H; Smith, AD; Williams, J1
Andrès, E; Dali-Youcef, N; Kaltenbach, G; Vogel, T1
Brady, CB; Cxypoliski, RA; Gaziano, JM; Goldfarb, DS; Guarino, PD; Hartigan, P; Jamison, RL; Kaufman, JS; Warren, SR1
Dillmann, U; Fassbender, K; Herrmann, W; Kostopoulos, P; Obeid, R; Schadt, A1
Alajbegovic, A; Fajkic, A; Hadzovic-Dzuvo, A; Kulo, A; Lepara, D; Lepara, O; Nakas-Icindic, E; Sofic, E; Valjevac, A; Zaciragic, A1
Litvinenko, IV; Mogil'naya, VI; Odinak, MM; Perstnev, SV1
Alexopoulos, P; Bleich, S; Herpertz, SC; Irmisch, G; Jung, SU; Kurz, A; Perneczky, R; Poppe, K; Prehn, K; Sebb, H; Topalidis, S1
Griffiths, HR; Li, L; Nelles, G; Polidori, MC; Sies, H; Stahl, W; Willets, RS1
Bleich, S; de Zwaan, M; Fischer, J; Frieling, H; Hillemacher, T; Kornhuber, J; Müller, E; Wilhelm, J1
Cho, E; Dougherty, L; Giovannucci, E; Jacques, PF; Lee, JE; Selhub, J; Zeisel, SH1
Cole, PD; Gulinello, M; Li, Y; Vijayanathan, V1
Caouette, H; Crott, JW; Lai, CQ; Lee, YC; Ordovás, JM; Parnell, LD; Qiu, WQ; Rosenberg, IH; Shen, J; Troen, AM; Tucker, KL; Warodomwichit, D1
Hudson, PR; McCaddon, A1
Handels, R; van Rossum, IA; Visser, PJ; Vos, S1
Aisen, PS; Blennow, K; Clark, CM; Dean, R; Jack, CR; Jagust, W; Korecka, M; Lee, VM; Lewczuk, P; Petersen, RC; Potter, WZ; Shaw, LM; Siemers, E; Simon, A; Soares, H; Toga, AW; Trojanowski, JQ; Vandeerstichele, H; Weiner, MW1
Ataee, R; Ataie, A; Haghparast, A; Moghaddam, AH; Moghaddam, SN; Sabetkasaei, M1
Graber, JJ; Kaufmann, H; Kolodny, EH; Sathe, S; Sherman, FT1
Ataie, A; Haghparast, A; Kazeminejad, B; Moghaddam, AH; Sabetkasaei, M1
Iliceto, G; Lamberti, P; Lamberti, SV; Logroscino, G; Santamato, A; Zoccolella, S1
Cheng, DM; Huang, CY; Jiang, YG; Kong, HY; Pang, W; Yang, HP1
Chang, CC; Chang, WN; Chen, C; Chen, CF; Chen, NC; Huang, CW; Lin, YT; Lui, CC; Tu, MC; Wang, YL1
Chen, S; Chen, X; Chen, Y; Chu, W; Ho, CL; Hu, X; Leung, EY; Mok, V; Schmidt, R; Tang, WK; Wong, A; Wong, KK; Wong, KS; Wong, ST; Xiong, Y1
Agacinski, G; Bradley, KM; de Jager, CA; Jacoby, R; Johnston, C; Oulhaj, A; Refsum, H; Smith, AD; Smith, SM; Whitbread, P1
Alfonso, H; Almeida, OP; Clarnette, R; Flicker, L; Ford, AH; Martins, R; Thomas, J1
Fedin, AI; Kaluga, AS; Mironova, OP; Solov'eva, EIu1
Fuchs, D; Greilberger, J; Greilberger, M; Leblhuber, F; Tafeit, E; Wintersteiger, R1
Rosenberg, IH; Selhub, J; Troen, A1
Benetos, A; Boivin, JM; Bracard, S; Fay, R; Felblinger, J; Kearney-Schwartz, A; Lacolley, P; Marteau, JB; Rossignol, P; Visvikis-Siest, S; Watfa, G; Zannad, F1
Choi, KC; Kwok, T; Lam, LC; Law, CB; Lee, J; Pan, PC; Yung, CY1
Beran-Praher, M; Fuchs, D; Haller, H; Leblhuber, F; Schroecksnadel, K; Steiner, K1
Almeida, OP; Flicker, L; Ford, AH; Hankey, GJ; Norman, P; van Bockxmeer, FM1
Brown, B; Huang, MH; Kado, D; Karlamangla, A; Seeman, T1
Chatthanawaree, W1
Geerlings, MI; Kloppenborg, RP; Nederkoorn, PJ; van der Graaf, Y1
Hua, X; Jack, CR; Rajagopalan, P; Thompson, PM; Toga, AW; Weiner, MW1
Firbank, MJ; Ford, GA; Hansrani, M; Harrington, F; McKeith, IG; Narayan, SK; O'Brien, JT; Saxby, BK; Stansby, G1
Bailey, RL; Blackmore, S; Bock, JL; Brody, LC; Carmel, R; Coates, PM; Curtin, LR; Durazo-Arvizu, RA; Eckfeldt, JH; Green, R; Gregory, JF; Hoofnagle, AN; Jacobsen, DW; Jacques, PF; Johnson, CL; Lacher, DA; Massaro, J; Mills, JL; Molloy, AM; Nexo, E; Pfeiffer, CM; Phinney, KW; Picciano, MF; Rader, JI; Selhub, J; Sempos, C; Shane, B; Stabler, S; Stover, P; Tamura, T; Tedstone, A; Thorpe, SJ; Yetley, EA1
de Jager, CA; Jacoby, R; Oulhaj, A; Refsum, H; Smith, AD1
Clarke, R; Fedosov, S; Hin, H; Lildballe, DL; Nexo, E; Sherliker, P1
Ali, N; Cole, PD; Gulinello, M; Vijayanathan, V1
Hänninen, T; Hooshmand, B; Kåreholt, I; Kivipelto, M; Laatikainen, T; Leiviskä, J; Rusanen, M; Soininen, H; Solomon, A; Winblad, B1
Chen, HH; Jin, QH; Li, TL; Li, XC; Liu, Z; Wang, S; Xu, L1
Alexopoulos, P; Bickel, H; Kurz, A; Perneczky, R1
D'Anci, KE; Dallal, GE; Dobson, B; Jacques, PF; Levey, AS; Moorthy, D; Rogers, G; Rosenberg, IH; Scott, TM; Selhub, J; Troen, AM; Weiner, DE1
Ayesa-Arriola, R; Crespo-Facorro, B; García-Unzueta, M; Gómez-Ruiz, E; Martínez-García, O; Mata, I; Pérez-Iglesias, R; Rodríguez-Sánchez, JM; Tabares-Seisdedos, R; Vázquez-Barquero, JL1
Almeida, OP; Arnolda, L; Beer, C; Flicker, L; Ford, AH; Garrido, GJ; Lautenschlager, NT1
Ben Abdallah, J; Charfeddine, B; Letaef, A; Limem, K; Naffeti, S; Othmen, LB; Smach, MA1
Crott, JW; Griffith, J; Lai, CQ; Moorthy, D; Ordovás, JM; Parnell, LD; Peter, I; Rosenberg, IH; Scott, TM; Selhub, J; Troen, AM; Tucker, KL1
Agarwal, R; Chandra, S; Kalita, J; Misra, UK1
de Groot, LC; Geerlings, MI; Jochemsen, HM; Kampman, E; Kloppenborg, RP; Mali, WP; van der Graaf, Y1
Białecka, M; Budrewicz, S; Droździk, M; Gorzkowska, A; Gołąb-Janowska, M; Honczarenko, K; Jarosz, M; Koziorowska-Gawron, E; Kurzawski, M; Mak, M; Robowski, P; Roszmann, A; Sitek, EJ; Sławek, J1
Baydas, G; Demir, N; Etem, A; Etem, EO; Koz, S; Koz, ST; Kuloğlu, T; Ozercan, HI; Yuce, H1
Chang, N; Kim, G; Kim, H; Kim, KN; Kim, SY; Son, JI; Tamura, T1
Morris, MS1
Drevon, CA; Engedal, K; Nurk, E; Nygaard, HA; Refsum, H; Smith, AD; Tell, GS; Ueland, PM; Vogiatzoglou, A; Vollset, SE1
Chen, KJ; Chen, RC; Huang, YC; Lee, MS; Li, D; Wahlqvist, ML; Xiu, LL1
Bahl, R; Bhandari, N; Refsum, H; Schneede, J; Sommerfelt, H; Strand, TA; Taneja, S; Ueland, PM1
Chee, MW; Feng, L; Isaac, V; Krishnan, KR; Ng, TP; Sim, S1
Asonganyi, B; Sherwood, R; Stewart, R1
Alpérovitch, A; Ducros, V; Dufouil, C; Tzourio, C1
Brodaty, H; Gillies, D; Howard, L; Jones, M; Looi, J; Lorentz, L; Sachdev, PS; Valenzuela, MJ; Wang, XL; Wilcken, DE; Zagami, AS1
Miller, AL1
Blom, HJ; Bosma, H; Bosmans, E; De Bruijn, C; de Vente, J; Delanghe, J; Jolles, J; Lütjohann, D; Maes, M; Steinbusch, HW; Teunissen, CE; van Boxtel, MP; von Bergmann, K; Wauters, A1
Gustafson, L; Hultberg, B; Isaksson, A; Nilsson, K2
Berner, YN; Doolman, R; Dror, Y; Gomori, JM; Isayev, M; Levy, S; Polyak, Z; Sela, BA; Stern, F1
Blom, AH; Bosma, H; de Bruijn, C; de Vente, J; Jolles, J; Steinbusch, HW; Teunissen, CE; Van Boxtel, MP; Wauters, BA1
Barcikowska, M; Chodakowska, M; Gabryelewicz, T; Golebiowski, M; Luczywek, E; Peplonska, B; Pfeffer, A; Religa, D; Stepien, K; Styczynska, M; Wasiak, B; Winblad, B1
Bickel, H; Förstl, H; Lautenschlager, N1
Clarke, R; Harrison, G; Richards, S1
Stabler, SP1
Allen, LH; Green, R; Haan, MN; Jagust, WJ; Miller, JW; Mungas, DM; Ramos, MI2
Costa, M; Hoff, AL; Sommer, BR1
Ashline, D; Milhalik, S; Ortiz, D; Rogers, E; Shea, TB1
Arai, H; Maruyama, M; Matsui, T; Nemoto, M; Ootsuki, M; Sasaki, H; Tanji, H; Tomita, N1
Selley, ML1
Acres, J; Almeida, OP; Flicker, L; Jamrozik, K; Martins, RN; Norman, P; Taddei, K; Thomas, J1
Bottiglieri, T; Dewey, RB; Diaz-Arrastia, R; Hernandez, C; Lacritz, L; O'Suilleabhain, PE; Sung, V1
Forloni, G; Fragiacomo, C; Lucca, U; Pezzati, R; Quadri, P; Tettamanti, M; Zanda, E1
Ellinson, M; Patterson, A; Thomas, J1
Allen, RH; Lee, HS; Paik, MC; Sacco, RL; Stabler, SP; Wright, CB1
Antonello, RM; Bava, A; Cattaruzza, T; Cazzato, G; Moretti, R; Torre, P1
Garcia, A; Zanibbi, K1
Almeida, OP; Flicker, L; Lautenschlager, NT; Leedman, P; van Bockxmeer, FM; Vasikaran, S1
Bressler, J; Glass, TA; Schafer, JH; Schwartz, BS; Todd, AC1
Huang, MH; Kado, DM; Karlamangla, AS; Rowe, JW; Seeman, TE; Selhub, J; Troen, A1
Engedal, K; Hestad, K; Kveberg, B1
Boxer, AL; Finley, R; Goldman, J; Johnston, K; Kramer, JH; Miller, BL1
Bayerlein, K; Bleich, S; Degner, D; Frieling, H; Hillemacher, T; Kornhuber, J; Kromolan, B; Reulbach, U; Wilhelm, J1
Rosenberg, I; Troen, A1
Almeida, OP; Flicker, L; Lautenschlager, NT; Leedman, P; Vasikaran, S1
Annerbo, S; Lökk, J; Wahlund, LO1
Sachdev, PS1
Au, R; Beiser, A; D'Agostino, RB; Elias, MF; Elias, PK; Jacques, PF; Selhub, J; Seshadri, S; Sullivan, LM; Wolf, PA1
Bottiglieri, T; Diaz-Arrastia, R1
Qiao, N; Rosenberg, I; Scott, T; Spiro, A; Tucker, KL1
Affenberger, S; Andrès, E; Blicklé, JF; Kaltenbach, G; Kurtz, JE; Maloisel, F; Noel, E; Schlienger, JL; Vinzio, S1
Blom, HJ; de Vente, J; Dijkstra, CD; Jolles, J; Polman, CH; Teunissen, CE; van Boxtel, MP; Verhey, F; Vreeling, F1
Fragiacomo, C; Lucca, U; Pezzati, R; Quadri, P; Tettamanti, M; Zanda, E1
Brennan, SL; Budge, MM; Elias, MF; Elias, PK; Robbins, MA1
Armenise, E; de Mari, M; Defazio, G; Diroma, C; Fraddosio, A; Iliceto, G; Lamberti, P; Lamberti, SV; Livrea, P; Zoccolella, S1
Bleich, S; Bönsch, D; de Zwaan, M; Frieling, H; Gruss, B; Hillemacher, T; Jacoby, GE; Kornhuber, J; Römer, KD; Röschke, B; Wilhelm, J1
Fan, YH; Lam, WW; Liang, KS; Mok, V; Wong, A; Wong, KS1
Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M1
McCaddon, A; Regland, B1
Bertoletti, E; Chilovi, BV; Conti, M; Del Rio, I; Padovani, A; Rozzini, L; Trabucchi, M1
Kalmijn, S; Mali, WP; van der Graaf, Y; van Raamt, AF; van Zandvoort, MJ1
Bjelland, I; Gjesdal, CG; Nurk, E; Nygård, O; Refsum, H; Smith, AD; Tell, GS; Tverdal, A; Ueland, PM; Vollset, SE1
Dichgans, M; Gschwendtner, A; Herzog, J; Holtmannspötter, M; Opherk, C; Peters, N; Sämann, P1
Bausserman, L; Cohen, RA; Gunstad, J; Hoth, K; Jefferson, AL; Paul, RH; Poppas, A; Tate, DF1
Green, TJ; Knight, RG; Mann, JI; McMahon, JA; Skeaff, CM; Williams, SM1
Bauer, K; Fischer, P; Huber, K; Jungwirth, S; Tragl, KH; Zehetmayer, S1
Blom, HJ; Bloo, RJ; Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Joosten, LW; Schneede, J; Ueland, PM; van Staveren, WA1
McCaddon, A1
Ampil, ER; Auchus, AP; Chen, CP; Tay, SY1
Lucca, U; Quadri, P; Tettamanti, M1
Green, TJ; Knight, RG; McMahon, J; Skeaff, CM1
Smith, AD2
Morris, MC; Tangney, CC1
Aiello, AE; Allen, LH; Green, R; Haan, MN; Jagust, WJ; Miller, JW; Mungas, DM; Whitmer, RA1
Anello, G; Babiloni, C; Bartesaghi, S; Benussi, L; Binetti, G; Bosco, P; Cassetta, E; Del Percio, C; Ferri, R; Frisoni, G; Ghidoni, R; Gurzì, M; Lanuzza, B; Lizio, R; Rossini, PM; Squitti, R; Tombini, M1
Ballard, C; Dickinson, HO; Kalaria, R; Kenny, RA; Rowan, EN; Stephens, S1
Nagayama, M1
Atanassova, PA1
Belmaker, RH; Bersudsky, Y; Osher, Y; Sela, BA; Silver, H1
Boziki, M; Chatzopoulos, D; Gavalas, E; Kapetanakis, N; Kountouras, J; Stergiopoulos, C; Tsolaki, M; Venizelos, I; Zavos, C1
Boziki, M; Gavalas, E; Kountouras, J; Zavos, C1
Birks, J; Clarke, R; Evans, JG; Molloy, A; Nexo, E; Schneede, J; Scott, J; Ueland, PM1
Bang, H; Hussain, SI; Newman, GC; Toole, JF1
De la Fuente, M; Frank, A; Hernanz, A; Navarro, M1
Aguglia, U; Battaglia, L; Condino, F; de Marco, V; Luise, F; Morabito, F; Morabito, P; Piromalli, A; Quattrone, A; Russo, C; Trapani Lombardo, V; Vinci, A1
Schulz, RJ1
Evered, L; Jamrozik, K; McCutcheon, C; Scott, DA; Silbert, B1
Bernhard, B; Born, C; Dargel, S; Dittmann, S; Engel, RR; Fast, K; Grunze, HC; Möller, HJ; Riedel, M; Schwarz, MJ; Seemüller, F; Severus, WE; Zach, J1
Ducros, V; Dufouil, C; Tzourio, C; Vidal, JS1
Bernard, MA; Kashner, TM; Nakonezny, PA1
Bots, ML; Breteler, MM; Hofman, A; Kalmijn, S; Launer, LJ; Lindemans, J1
Gussekloo, J; Heijmans, BT; Knook, DL; Lagaay, AM; Slagboom, PE; Westendorp, RG1
Bagley, LC; Miller, J; Rosenberg, IH; Selhub, J1
Breteler, MM1
Bargossi, AM; Caldarera, M; Cavalli, G; Facchini, A; Forti, P; Franceschi, C; Grossi, G; Maioli, F; Mariani, E; Ravaglia, G; Vettori, C1
Artner-Dworzak, E; Fuchs, D; Leblhuber, F; Reibnegger, G; Vrecko, K; Walli, J; Widner, B1
Rosenberg, IH1
Blennow, K; Gottfries, CG; Gottfries, J; Lehmann, MW; Regland, B1
Norberg, B1
Aller, R; Arranz, M; de Luis, DA; Fernandez, N; Izaola, O1
Hankey, GJ1
Bell, IR; Cole, JO; Edman, JS; Kayne, HL; Marby, DW; Morrow, FD; Selhub, J1

Reviews

41 review(s) available for homocysteine and Cognition Disorders

ArticleYear
The Link between Homocysteine and Omega-3 Polyunsaturated Fatty Acid: Critical Appraisal and Future Directions.
    Biomolecules, 2020, 02-02, Volume: 10, Issue:2

    Topics: Animals; Cardiovascular Diseases; Cognition Disorders; Dietary Supplements; Fatty Acids, Omega-3; Fish Oils; Homocysteine; Humans; Oxidative Stress; Risk Factors; Vitamin B Complex

2020
Effect of Vitamin B Supplementation on Cognitive Function in the Elderly: A Systematic Review and Meta-Analysis.
    Drugs & aging, 2019, Volume: 36, Issue:5

    Topics: Aged; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2019
Homocysteine: A modifiable culprit of cognitive impairment for us to conquer?
    Journal of the neurological sciences, 2019, Sep-15, Volume: 404

    Topics: Cognition Disorders; Cognitive Dysfunction; Homocysteine; Humans

2019
Effect of B vitamins and lowering homocysteine on cognitive impairment in patients with previous stroke or transient ischemic attack: a prespecified secondary analysis of a randomized, placebo-controlled trial and meta-analysis.
    Stroke, 2013, Volume: 44, Issue:8

    Topics: Aged; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Ischemic Attack, Transient; Male; Middle Aged; Placebos; Recurrence; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B Complex

2013
Critical levels of brain atrophy associated with homocysteine and cognitive decline.
    Neurobiology of aging, 2014, Volume: 35 Suppl 2

    Topics: Atrophy; Brain; Cognition Disorders; Folic Acid; Homocysteine; Humans; Vitamin B 12 Deficiency; Vitamin B Complex

2014
Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis.
    BMC public health, 2014, Jun-24, Volume: 14

    Topics: Alcohol Drinking; Alzheimer Disease; Antioxidants; Caffeine; Cognition; Cognition Disorders; Dementia; Diet; Educational Status; Exercise; Fatty Acids, Omega-3; Female; Homocysteine; Humans; Male; Smoking

2014
Effect of Vitamin Intake on Cognitive Decline in Older Adults: Evaluation of the Evidence.
    The journal of nutrition, health & aging, 2015, Volume: 19, Issue:7

    Topics: Aged; Antioxidants; Ascorbic Acid; beta Carotene; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Folic Acid; Homocysteine; Humans; Meta-Analysis as Topic; Vitamin A; Vitamin B 12; Vitamin B 6; Vitamin D; Vitamin D Deficiency; Vitamin E; Vitamins

2015
Homocysteine, B Vitamins, and Cognitive Impairment.
    Annual review of nutrition, 2016, 07-17, Volume: 36

    Topics: Aging; Animals; Biomarkers; Cerebrovascular Circulation; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nootropic Agents; Nutritional Status; Practice Guidelines as Topic; Risk Factors; Vitamin B 12; Vitamin B 6

2016
Homocysteine and cognition: A systematic review of 111 studies.
    Neuroscience and biobehavioral reviews, 2016, Volume: 69

    Topics: Cognition; Cognition Disorders; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Vitamin B 12

2016
Cognitive decline: A vitamin B perspective.
    Maturitas, 2016, Volume: 93

    Topics: Cognition; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Homocysteine; Humans; Memory; Vitamin B Complex

2016
Association of plasma homocysteine, vitamin B12 and folate levels with cognitive function in Parkinson's disease: A meta-analysis.
    Neuroscience letters, 2017, 01-01, Volume: 636

    Topics: Adult; Aged; Aged, 80 and over; Cognition; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Treatment Outcome; Vitamin B 12

2017
Efficacy of Vitamin B Supplementation on Cognition in Elderly Patients With Cognitive-Related Diseases.
    Journal of geriatric psychiatry and neurology, 2017, Volume: 30, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2017
Exercise and cognition in older adults: is there a role for resistance training programmes?
    British journal of sports medicine, 2009, Volume: 43, Issue:1

    Topics: Accidental Falls; Aged; Cognition; Cognition Disorders; Fractures, Bone; Homocysteine; Humans; Insulin-Like Growth Factor I; Resistance Training

2009
Homocysteine, vitamin B12, folate and cognitive functions: a systematic and critical review of the literature.
    International journal of clinical practice, 2009, Volume: 63, Issue:7

    Topics: Adult; Clinical Trials as Topic; Cognition Disorders; Cross-Sectional Studies; Dietary Supplements; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2009
L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline.
    CNS spectrums, 2010, Volume: 15, Issue:1 Suppl 1

    Topics: Acetylcysteine; Alzheimer Disease; Cognition Disorders; Free Radical Scavengers; Homocysteine; Humans; Oxidative Stress; Plaque, Amyloid; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex

2010
Biomarkers as predictors for conversion from mild cognitive impairment to Alzheimer-type dementia: implications for trial design.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Clinical Trials as Topic; Cognition Disorders; Disease Progression; Homocysteine; Humans; Lipid Metabolism; Peptide Fragments; tau Proteins

2010
Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2010, Volume: 6, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Biomarkers; Cognition Disorders; Cross-Sectional Studies; Diagnostic Imaging; Homocysteine; Humans; Isoprostanes; Peptide Fragments; Positron-Emission Tomography; Prospective Studies; Reproducibility of Results; tau Proteins; Thiazoles

2010
Hyperhomocysteinemia in L-dopa treated patients with Parkinson's disease: potential implications in cognitive dysfunction and dementia?
    Current medicinal chemistry, 2010, Volume: 17, Issue:28

    Topics: Antiparkinson Agents; Cognition Disorders; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Neurons; Parkinson Disease

2010
B vitamins and the aging brain.
    Nutrition reviews, 2010, Volume: 68 Suppl 2

    Topics: Aged; Aging; Brain; Cognition Disorders; Homocysteine; Humans; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex

2010
Biomarkers of cobalamin (vitamin B12) deficiency and its application.
    The journal of nutrition, health & aging, 2011, Volume: 15, Issue:3

    Topics: Aging; Biomarkers; Cognition Disorders; Erythrocyte Indices; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency

2011
Biomarkers of vitamin B-12 status in NHANES: a roundtable summary.
    The American journal of clinical nutrition, 2011, Volume: 94, Issue:1

    Topics: Biomarkers; Cognition Disorders; Homocysteine; Humans; Methylmalonic Acid; Nutrition Surveys; Public Health; Vitamin B 12; Vitamin B 12 Deficiency

2011
Effect of homocysteine lowering treatment on cognitive function: a systematic review and meta-analysis of randomized controlled trials.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 29, Issue:1

    Topics: Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Randomized Controlled Trials as Topic; Treatment Outcome; Vitamin B 12; Vitamin B 6

2012
[Homocysteine, vitamin B-12, folic acid and the cognitive decline in the elderly].
    Pathologie-biologie, 2013, Volume: 61, Issue:5

    Topics: Aged; Brain; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nutritional Physiological Phenomena; Receptors, N-Methyl-D-Aspartate; Risk Factors; Vitamin B 12

2013
The role of B vitamins in preventing and treating cognitive impairment and decline.
    Advances in nutrition (Bethesda, Md.), 2012, Nov-01, Volume: 3, Issue:6

    Topics: Alzheimer Disease; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylation; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency

2012
The methionine-homocysteine cycle and its effects on cognitive diseases.
    Alternative medicine review : a journal of clinical therapeutic, 2003, Volume: 8, Issue:1

    Topics: Alzheimer Disease; Cardiovascular Diseases; Cognition Disorders; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Memory Disorders; Methionine; Methionine Adenosyltransferase; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6

2003
Mild cognitive impairment: making headway by stepping backwards.
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2003, Volume: 105, Issue:4

    Topics: Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cognition Disorders; Comorbidity; Diabetes Mellitus; Estrogen Replacement Therapy; Homocysteine; Humans; Hypercholesterolemia; Hypertension; Inflammation; Middle Aged; Prevalence; Risk Factors; Vitamin B 12 Deficiency

2003
A critical evaluation of the relationship between serum vitamin B, folate and total homocysteine with cognitive impairment in the elderly.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2004, Volume: 17, Issue:4

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognition Disorders; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12

2004
Vitamin B12 and folate depletion in cognition: a review.
    Neurology India, 2004, Volume: 52, Issue:3

    Topics: Cognition; Cognition Disorders; Dementia; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency

2004
Homocysteine and cognitive function in elderly people.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Oct-12, Volume: 171, Issue:8

    Topics: Aged; Aged, 80 and over; Cognition Disorders; Dementia; Genetic Predisposition to Disease; Homocysteine; Humans; Middle Aged; Risk Factors; Vitamin B Complex

2004
Homocysteine and cognitive function.
    Seminars in vascular medicine, 2005, Volume: 5, Issue:2

    Topics: Cognition; Cognition Disorders; Dementia; Dietary Supplements; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex

2005
Homocysteine and brain atrophy.
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:7

    Topics: Alcoholism; Animals; Atrophy; Brain Diseases; Cognition Disorders; Homocysteine; Humans; Hyperhomocysteinemia

2005
Homocysteine in relation to cognitive performance in pathological and non-pathological conditions.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:10

    Topics: Animals; Central Nervous System; Cognition; Cognition Disorders; Homocysteine; Humans; Multiple Sclerosis

2005
The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Adult; Aged; Aging; Bone Density; Cardiovascular Diseases; Cognition Disorders; Depression; Disease; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mortality; Norway; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors

2006
Homocysteine and cognition--a historical perspective.
    Journal of Alzheimer's disease : JAD, 2006, Volume: 9, Issue:4

    Topics: Alzheimer Disease; Anemia, Pernicious; Cognition Disorders; Folic Acid Deficiency; History, 19th Century; History, 20th Century; History, 21st Century; Homocysteine; Humans; Vitamin B 12 Deficiency

2006
[Homocysteine].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Oct-28, Volume: 64 Suppl 7

    Topics: Brain Diseases; Cerebral Infarction; Cognition Disorders; Homocysteine; Humans; Risk Factors

2006
Homocysteine as a biomarker for cognitive dysfunction in the elderly.
    Current opinion in clinical nutrition and metabolic care, 2007, Volume: 10, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Cognition Disorders; Diagnosis, Differential; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Predictive Value of Tests; Vitamin B Complex

2007
B vitamins, homocysteine, and neurocognitive function in the elderly.
    The American journal of clinical nutrition, 2000, Volume: 71, Issue:2

    Topics: Aging; Animals; Brain; Cognition Disorders; Homocysteine; Humans; Methionine; Tetrahydrofolates; Vitamin B Deficiency

2000
[Homocysteine and methylmalonic acid as markers of cobalamin/folate status. The association to neuropsychiatric symptoms in the elderly is explored].
    Lakartidningen, 2000, Sep-20, Volume: 97, Issue:38

    Topics: Aged; Biomarkers; Cognition Disorders; Diagnosis, Differential; Folic Acid Deficiency; Geriatric Psychiatry; Homocysteine; Humans; Mental Disorders; Methylmalonic Acid; Reference Values; Vitamin B 12 Deficiency

2000
B vitamins, homocysteine, and neurocognitive function.
    Nutrition reviews, 2001, Volume: 59, Issue:8 Pt 2

    Topics: Aging; Alzheimer Disease; Cognition Disorders; Gastritis, Atrophic; Homocysteine; Humans; Nutritional Status; Vitamin B Deficiency

2001
Is homocysteine a causal and treatable risk factor for vascular diseases of the brain (cognitive impairment and stroke)?
    Annals of neurology, 2002, Volume: 51, Issue:3

    Topics: Cognition Disorders; Homocysteine; Humans; Risk Factors; Stroke

2002
Homocysteine, B vitamins, and cognitive deficit in the elderly.
    The American journal of clinical nutrition, 2002, Volume: 75, Issue:5

    Topics: Aging; Cognition Disorders; Folic Acid; Homocysteine; Humans; Vitamin B 12

2002

Trials

23 trial(s) available for homocysteine and Cognition Disorders

ArticleYear
B-Vitamin Therapy for Kidney Transplant Recipients Lowers Homocysteine and Improves Selective Cognitive Outcomes in the Randomized FAVORIT Ancillary Cognitive Trial.
    The journal of prevention of Alzheimer's disease, 2017, Volume: 4, Issue:3

    Topics: Cognition; Cognition Disorders; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; North America; Postoperative Complications; Treatment Outcome; Vitamin B Complex

2017
Vitamin B12 and Homocysteine Levels Predict Different Outcomes in Early Parkinson's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2018, Volume: 33, Issue:5

    Topics: alpha-Tocopherol; Antioxidants; Antiparkinson Agents; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Male; Mental Status Schedule; Middle Aged; Parkinson Disease; Predictive Value of Tests; Selegiline; Treatment Outcome; Vitamin B 12

2018
The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial.
    Nutrients, 2018, Dec-01, Volume: 10, Issue:12

    Topics: Adult; Aged; Antioxidants; Aspartic Acid; Biomarkers; Brain; Cognition; Cognition Disorders; Creatine; Dietary Supplements; Double-Blind Method; Female; Homocysteine; Humans; Inflammation; Male; Middle Aged; Oxidative Stress; Vitamin B Complex

2018
Effect of B vitamins and lowering homocysteine on cognitive impairment in patients with previous stroke or transient ischemic attack: a prespecified secondary analysis of a randomized, placebo-controlled trial and meta-analysis.
    Stroke, 2013, Volume: 44, Issue:8

    Topics: Aged; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Ischemic Attack, Transient; Male; Middle Aged; Placebos; Recurrence; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B Complex

2013
Brain atrophy in cognitively impaired elderly: the importance of long-chain ω-3 fatty acids and B vitamin status in a randomized controlled trial.
    The American journal of clinical nutrition, 2015, Volume: 102, Issue:1

    Topics: Aged; Atrophy; Body Mass Index; Brain; Cognition Disorders; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Nutritional Status; Retrospective Studies; Vitamin B Complex

2015
Improved blood biomarkers but no cognitive effects from 16 weeks of multivitamin supplementation in healthy older adults.
    Nutrients, 2015, May-19, Volume: 7, Issue:5

    Topics: Aged; Aging; Biomarkers; C-Reactive Protein; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Female; Homocysteine; Humans; Lipids; Male; Middle Aged; Oxidative Stress; Reference Values; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamins

2015
Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial.
    The Lancet. Neurology, 2016, Volume: 15, Issue:8

    Topics: Adaptation, Psychological; Adult; Catechin; Cholesterol; Cognition Disorders; Cognitive Behavioral Therapy; Double-Blind Method; Down Syndrome; Female; Follow-Up Studies; Homocysteine; Humans; Inhibition, Psychological; Male; Neuroprotective Agents; Recognition, Psychology; Retrospective Studies; Spain; Treatment Outcome; Young Adult

2016
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial.
    JAMA, 2008, Oct-15, Volume: 300, Issue:15

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Psychiatric Status Rating Scales; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2008
A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease.
    The American journal of clinical nutrition, 2008, Volume: 88, Issue:6

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Chi-Square Distribution; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Psychometrics; Risk Factors; Statistics, Nonparametric; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2008
Homocysteine lowering and cognition in CKD: the Veterans Affairs homocysteine study.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:3

    Topics: Age Factors; Aged; Cognition; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Risk Factors; United States; United States Department of Veterans Affairs; Vitamin B Complex

2009
Use of memantine (akatinol) for the correction of cognitive impairments in Parkinson's disease complicated by dementia.
    Neuroscience and behavioral physiology, 2010, Volume: 40, Issue:2

    Topics: Activities of Daily Living; Aged; Antiparkinson Agents; Cognition; Cognition Disorders; Dementia; Disability Evaluation; Dyskinesias; Homocysteine; Humans; Levodopa; Memantine; Neuropsychological Tests; Nootropic Agents; Parkinson Disease; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Treatment Outcome

2010
Cortical and frontal atrophy are associated with cognitive impairment in age-related confluent white-matter lesion.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:1

    Topics: Aged; Aging; Atrophy; Cerebral Amyloid Angiopathy; Cerebral Cortex; Cognition Disorders; Double-Blind Method; Executive Function; Female; Frontal Lobe; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Predictive Value of Tests; Regression Analysis; Stroke

2011
Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial.
    PloS one, 2010, Sep-08, Volume: 5, Issue:9

    Topics: Aged; Aged, 80 and over; Atrophy; Brain; Cognition Disorders; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Radiography; Treatment Outcome; Vitamin B Complex

2010
Vitamins B(12), B(6), and folic acid for cognition in older men.
    Neurology, 2010, Oct-26, Volume: 75, Issue:17

    Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Community Health Planning; Dementia; Dietary Supplements; Double-Blind Method; Folic Acid; Follow-Up Studies; Geriatrics; Homocysteine; Humans; Male; Neuropsychological Tests; Patient Compliance; Time Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2010
A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people.
    Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Hong Kong; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Patient Dropouts; Vitamin B 12; Vitamin B Complex

2011
Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial.
    International journal of geriatric psychiatry, 2012, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Double-Blind Method; Executive Function; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Memory; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2012
Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:2

    Topics: Biomarkers; Child Development; Cognition Disorders; Cohort Studies; Developmental Disabilities; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; India; Infant; Male; Methylmalonic Acid; Neurogenesis; Nutritional Status; Prevalence; Psychomotor Performance; Vitamin B 12; Vitamin B 12 Deficiency

2013
Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia.
    Journal of internal medicine, 2003, Volume: 254, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Cognition Disorders; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Isoprostanes; Male; Middle Aged; Oxidative Stress; Platelet Activation; Platelet Aggregation Inhibitors; Riboflavin; Thromboxanes; Vitamin B 12; Vitamins

2003
Folic acid supplementation in dementia: a preliminary report.
    Journal of geriatric psychiatry and neurology, 2003, Volume: 16, Issue:3

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Prevalence; Risk Factors

2003
A controlled trial of homocysteine lowering and cognitive performance.
    The New England journal of medicine, 2006, Jun-29, Volume: 354, Issue:26

    Topics: Aged; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Psychological Tests; Vitamin B 12; Vitamin B Complex

2006
Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: a randomized, placebo-controlled trial.
    The American journal of clinical nutrition, 2006, Volume: 84, Issue:2

    Topics: Administration, Oral; Aged; Aged, 80 and over; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Methylmalonic Acid; Psychomotor Performance; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency

2006
Regression equations for predicting scores of persons over 65 on the rey auditory verbal learning test, the mini-mental state examination, the trail making test and semantic fluency measures.
    The British journal of clinical psychology, 2006, Volume: 45, Issue:Pt 3

    Topics: Aged; Aged, 80 and over; Attention; Cognition Disorders; Double-Blind Method; Female; Homocysteine; Humans; Intelligence; Male; Mental Recall; Mental Status Schedule; Neuropsychological Tests; Outcome Assessment, Health Care; Psychometrics; Reference Values; Semantics; Speech Perception; Statistics as Topic; Verbal Behavior; Verbal Learning; Vitamins

2006
Improvement of cognitive functions after cobalamin/folate supplementation in elderly patients with dementia and elevated plasma homocysteine.
    International journal of geriatric psychiatry, 2001, Volume: 16, Issue:6

    Topics: Aged; Attention; Biomarkers; Cognition Disorders; Dementia; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Mental Status Schedule; Vitamin B 12

2001

Other Studies

179 other study(ies) available for homocysteine and Cognition Disorders

ArticleYear
Association of serum homocysteine levels with intestinal flora and cognitive function in schizophrenia.
    Journal of psychiatric research, 2023, Volume: 159

    Topics: Cognition; Cognition Disorders; Gastrointestinal Microbiome; Homocysteine; Humans; Schizophrenia

2023
Prenatal folate, homocysteine and vitamin B
    The British journal of nutrition, 2019, Volume: 122, Issue:s1

    Topics: Brain; Child; Child Behavior Disorders; Cognition Disorders; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Language Development Disorders; Magnetic Resonance Imaging; Male; Netherlands; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency

2019
Association between homocysteine and third ventricle dilatation, mesencephalic area atrophy in Parkinson's disease with cognitive impairment.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 90

    Topics: Aged; Aged, 80 and over; Atrophy; Case-Control Studies; Cognition Disorders; Female; Homocysteine; Humans; Male; Mesencephalon; Middle Aged; Odds Ratio; Parkinson Disease; Risk Factors; Third Ventricle; Ultrasonography, Doppler, Transcranial

2021
One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond.
    Alzheimer's research & therapy, 2017, Jun-17, Volume: 9, Issue:1

    Topics: Aged; Alzheimer Disease; Biomarkers; Carbon; Carbon Compounds, Inorganic; Cognition Disorders; Comorbidity; Female; Homocysteine; Humans; Male; Prevalence; Risk Factors; Switzerland

2017
Correlations Between Methionine Cycle Metabolism, COMT Genotype, and Polyneuropathy in L-Dopa Treated Parkinson's Disease: A Preliminary Cross-Sectional Study.
    Journal of Parkinson's disease, 2017, Volume: 7, Issue:4

    Topics: Aged; Catechol O-Methyltransferase; Cognition Disorders; Cross-Sectional Studies; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Single Nucleotide; Polyneuropathies; Statistics, Nonparametric; Vitamins

2017
Serum homocysteine levels in patients with probable vascular dementia.
    Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, 2017, Aug-01, Volume: 14, Issue:2

    Topics: Aged; Aged, 80 and over; Brief Psychiatric Rating Scale; Case-Control Studies; Cognition Disorders; Cross-Sectional Studies; Dementia, Vascular; Female; Homocysteine; Humans; Male

2017
Relation of serum levels of homocysteine, vitamin B12 and folate to cognitive functions in multiple sclerosis patients.
    The International journal of neuroscience, 2018, Volume: 128, Issue:9

    Topics: Adult; Brain; Case-Control Studies; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Linear Models; Magnetic Resonance Imaging; Male; Multiple Sclerosis; Psychometrics; Statistics, Nonparametric; Vitamin B 12

2018
Evaluation of diffusion tensor imaging changes and neurocognitive effects of asymptomatic vitamin B12 deficiency.
    Acta neurologica Belgica, 2018, Volume: 118, Issue:2

    Topics: Adolescent; Adult; Brain; Cognition Disorders; Diffusion Tensor Imaging; Female; Homocysteine; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Vitamin B 12 Deficiency; Young Adult

2018
Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 63, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Cognition Disorders; Disease Models, Animal; Homocysteine; Male; Maze Learning; Moringa oleifera; Nerve Tissue Proteins; Neurons; Oxidative Stress; Peptide Fragments; Phosphorylation; Plant Extracts; Rats; Rats, Sprague-Dawley; Silver Staining; tau Proteins

2018
High altitude with monotonous environment has significant impact on mood and cognitive performance of acclimatized lowlanders: Possible role of altered serum BDNF and plasma homocysteine level.
    Journal of affective disorders, 2018, Volume: 237

    Topics: Acclimatization; Adult; Altitude; Biomarkers; Brain-Derived Neurotrophic Factor; Cognition Disorders; Environment; Homocysteine; Humans; Male; Mood Disorders

2018
Methotrexate causes persistent deficits in memory and executive function in a juvenile animal model.
    Neuropharmacology, 2018, 09-01, Volume: 139

    Topics: Animals; Brain; Cell Proliferation; Cognition Disorders; Executive Function; Female; Folic Acid Antagonists; Homocysteine; Male; Memory Disorders; Methotrexate; Microglia; Pattern Recognition, Visual; Rats, Long-Evans; Recognition, Psychology; Spatial Memory

2018
Decreased functional connectivity within the default-mode network in acute brainstem ischemic stroke.
    European journal of radiology, 2018, Volume: 105

    Topics: Biomarkers; Brain Ischemia; Brain Stem; Cognition Disorders; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Prefrontal Cortex; Signal Processing, Computer-Assisted; Stroke

2018
Clinical and imaging characteristics of subacute combined degeneration complicated with white matter lesions in the brain: a report of five cases.
    Somatosensory & motor research, 2018, Volume: 35, Issue:2

    Topics: Aged; Atrophy; Cognition Disorders; Female; Homocysteine; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Retrospective Studies; Subacute Combined Degeneration; Vitamin B 12

2018
The impact of homocysteine, B
    BMC infectious diseases, 2019, Feb-04, Volume: 19, Issue:1

    Topics: Adult; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; HIV; HIV Seropositivity; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Vitamin D; Vitamin D Deficiency; Vitamins

2019
Advanced age as a risk factor for folate-associated functional cobalamin deficiency.
    Journal of the American Geriatrics Society, 2013, Volume: 61, Issue:4

    Topics: Aged; Aged, 80 and over; Causality; Cognition Disorders; Comorbidity; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Male; Methylmalonic Acid; Risk Factors; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency

2013
Impact of homocysteine on cortical perfusion and cognitive decline in mild Alzheimer's dementia.
    European journal of neurology, 2013, Volume: 20, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cerebrovascular Circulation; Cognition Disorders; Disease Progression; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Perfusion; Risk Factors; Tomography, Emission-Computed, Single-Photon

2013
Homocysteine levels and cognitive function scores measured with MMSE and BCAT of middle-aged and elderly subjects in Tianjin City.
    The journal of nutrition, health & aging, 2013, Volume: 17, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; China; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intelligence Tests; Linear Models; Male; Middle Aged; Neuropsychological Tests; Prevalence; Sex Factors; Surveys and Questionnaires

2013
Association between total plasma homocysteine level and cognitive functions in elderly Egyptian subjects.
    Journal of the neurological sciences, 2013, Sep-15, Volume: 332, Issue:1-2

    Topics: Aged; Aging; Basilar Artery; Cognition Disorders; Egypt; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Mental Status Schedule; Neuropsychological Tests; Vertebral Artery

2013
Homocysteine, depression and cognitive function in older adults.
    Journal of affective disorders, 2013, Volume: 151, Issue:2

    Topics: Aged; Cognition Disorders; Cross-Sectional Studies; Depressive Disorder, Major; Female; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic

2013
Role of plasma homocysteine levels and MTHFR polymorphisms on IQ scores in children and young adults with epilepsy treated with antiepileptic drugs.
    Epilepsy & behavior : E&B, 2013, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Child; Cognition Disorders; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Intelligence Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Polymorphism, Genetic; Statistics, Nonparametric; Vitamin B 12; Young Adult

2013
Interactions between plasma concentrations of folate and markers of vitamin B(12) status with cognitive performance in elderly people not exposed to folic acid fortification: the Hordaland Health Study.
    The British journal of nutrition, 2014, Mar-28, Volume: 111, Issue:6

    Topics: Aged; Biomarkers; Cognition Disorders; Cross-Sectional Studies; Diet; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Norway; Nutritional Status; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency

2014
Association of homocysteine with hippocampal volume independent of cerebral amyloid and vascular burden.
    Neurobiology of aging, 2014, Volume: 35, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cognition Disorders; Cognitive Dysfunction; Female; Hippocampus; Homocysteine; Humans; Linear Models; Male; Middle Aged; Risk Factors

2014
Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles.
    Annals of neurology, 2014, Volume: 75, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cell Line, Tumor; Cognition Disorders; Diet; Disease Models, Animal; Homocysteine; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neuroblastoma; Neurofibrillary Tangles; Plaque, Amyloid; Presenilin-1; Signal Transduction; tau Proteins

2014
[Correlation between serum levels of homocysteine and folate and cognitive dysfunction in first-episode schizophrenics].
    Zhonghua yi xue za zhi, 2014, Apr-08, Volume: 94, Issue:13

    Topics: Adolescent; Adult; Case-Control Studies; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Schizophrenia; Vitamin B 12; Young Adult

2014
Fatty acid status and its relationship to cognitive decline and homocysteine levels in the elderly.
    Nutrients, 2014, Sep-12, Volume: 6, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cognition; Cognition Disorders; Dementia; Diet; Docosahexaenoic Acids; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Geriatric Assessment; Homocysteine; Humans; Lipids; Male; Memory; Nutritional Status; Risk Factors

2014
Effects of differences in serum total homocysteine, folate, and vitamin B12 on cognitive impairment in stroke patients.
    BMC neurology, 2014, Nov-30, Volume: 14

    Topics: Adult; Aged; Brain; Case-Control Studies; Cognition; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12

2014
Association between intake of B vitamins and cognitive function in elderly Koreans with cognitive impairment.
    Nutrition journal, 2014, Dec-17, Volume: 13, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Republic of Korea; Vitamin B 12; Vitamin B Complex

2014
Associations between Alzheimer's disease and blood homocysteine, vitamin B12, and folate: a case-control study.
    Current Alzheimer research, 2015, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Chromatography, High Pressure Liquid; Cognition Disorders; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Psychiatric Status Rating Scales; Retrospective Studies; Surveys and Questionnaires; Vitamin B 12

2015
Elevated levels of plasma homocysteine, deficiencies in dietary folic acid and uracil-DNA glycosylase impair learning in a mouse model of vascular cognitive impairment.
    Behavioural brain research, 2015, Apr-15, Volume: 283

    Topics: Animals; Basilar Artery; Brain; Carotid Artery Diseases; Cerebrovascular Disorders; Chronic Disease; Cognition Disorders; Diet; Disease Models, Animal; Female; Folic Acid Deficiency; Glial Fibrillary Acidic Protein; Gliosis; Homocysteine; Learning Disabilities; Male; Matrix Metalloproteinase 9; Maze Learning; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Random Allocation; Uracil-DNA Glycosidase

2015
Homocysteine and cognitive disorders of postmenopausal women measured by a battery of computer tests--central nervous system vital signs.
    Archives of women's mental health, 2015, Volume: 18, Issue:4

    Topics: Aged; Apolipoproteins E; Attention; Biomarkers; Cognition; Cognition Disorders; Diagnosis, Computer-Assisted; Executive Function; Female; Homocysteine; Humans; Memory; Middle Aged; Neuropsychological Tests; Polymorphism, Genetic; Postmenopause; Prevalence; Socioeconomic Factors

2015
Cognitive Status According to Homocysteine and B-Group Vitamins in Elderly Adults.
    Journal of the American Geriatrics Society, 2015, Volume: 63, Issue:6

    Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Comorbidity; Confidence Intervals; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Odds Ratio; Prevalence; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency

2015
Ethanol extract of Brazilian propolis ameliorates cognitive dysfunction and suppressed protein aggregations caused by hyperhomocysteinemia.
    Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:11

    Topics: Animals; Antioxidants; Cognition Disorders; Diet; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Oxidative Stress; Propolis; Protein Aggregation, Pathological; Reactive Oxygen Species; Risk Factors

2015
Increased levels of plasma amyloid-beta are related to cortical thinning and cognitive decline in cognitively normal elderly subjects.
    Neurobiology of aging, 2015, Volume: 36, Issue:10

    Topics: Aged; Aging; Alzheimer Disease; Amyloid beta-Peptides; Cerebral Cortex; Cognition; Cognition Disorders; Female; Homocysteine; Humans; Male; Peptide Fragments; Risk Factors

2015
Assessing the association between homocysteine and cognition: reflections on Bradford Hill, meta-analyses, and causality.
    Nutrition reviews, 2015, Volume: 73, Issue:10

    Topics: Cognition; Cognition Disorders; Dementia; Dietary Supplements; Folic Acid; Homocysteine; Humans; Meta-Analysis as Topic; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2015
The expression features of serum Cystatin C and homocysteine of Parkinson's disease with mild cognitive dysfunction.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:16

    Topics: Aged; Cognition Disorders; Cystatin C; Female; Homocysteine; Humans; Male; Middle Aged; Parkinson Disease

2015
Association of homocysteine level and vascular burden and cognitive function in middle-aged and older adults with chronic kidney disease.
    International journal of geriatric psychiatry, 2016, Volume: 31, Issue:7

    Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Cognition; Cognition Disorders; Cognitive Dysfunction; Executive Function; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Renal Insufficiency, Chronic; Risk Factors; Vascular Diseases

2016
High homocysteine and epistasis between MTHFR and APOE: association with cognitive performance in the elderly.
    Experimental gerontology, 2016, Volume: 76

    Topics: Age Factors; Aged; Aging; Apolipoproteins E; Biomarkers; Cognition; Cognition Disorders; Cross-Sectional Studies; Epistasis, Genetic; Executive Function; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Phenotype; Polymorphism, Genetic; Principal Component Analysis; Risk Factors; Up-Regulation

2016
Homocysteine, antioxidant vitamins and lipids as biomarkers of neurodegeneration in Alzheimer's disease versus non-Alzheimer's dementia.
    Annals of agricultural and environmental medicine : AAEM, 2016, Volume: 23, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Biomarkers; Cognition Disorders; Dementia; Female; Homocysteine; Humans; Lipids; Male; Middle Aged; Vitamins

2016
Targeting therapy for homocysteic acid in the blood represents a potential recovery treatment for cognition in Alzheimer's disease patients.
    Aging, 2016, 09-14, Volume: 8, Issue:9

    Topics: Alzheimer Disease; Animals; Antibodies; Cognition Disorders; Disease Models, Animal; Homocysteine; Mice

2016
Correlation of Homocysteine with Cerebral Hemodynamic Abnormality, Endothelial Dysfunction Markers, and Cognition Impairment in Patients with Traumatic Brain Injury.
    World neurosurgery, 2017, Volume: 97

    Topics: Adult; Aged; Brain Injuries, Traumatic; Cerebrovascular Circulation; Cerebrovascular Disorders; Cognition Disorders; Cross-Sectional Studies; Endothelial Cells; Female; Follow-Up Studies; Glasgow Coma Scale; Homocysteine; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Neuropsychological Tests; Pulsatile Flow; Severity of Illness Index; Vascular Cell Adhesion Molecule-1

2017
Hydrogen Sulfide Ameliorates Homocysteine-Induced Cognitive Dysfunction by Inhibition of Reactive Aldehydes Involving Upregulation of ALDH2.
    The international journal of neuropsychopharmacology, 2017, 04-01, Volume: 20, Issue:4

    Topics: Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Cognition Disorders; Disease Models, Animal; Gasotransmitters; Glutathione; Hippocampus; Homocysteine; Hydrogen Sulfide; Injections, Intraventricular; Male; Maze Learning; Quinolines; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Spatial Navigation; Thiazolidinediones; Up-Regulation

2017
Testing for homocysteine in clinical practice.
    Nutrition and health, 2017, Volume: 23, Issue:1

    Topics: Alzheimer Disease; Blood Chemical Analysis; Cardiovascular Diseases; Cognition Disorders; Delivery of Health Care; Homocysteine; Humans; Hyperhomocysteinemia; Practice Patterns, Physicians'

2017
[Does an association between increased homocystein levels and cognitive dysfunction also exist in multimorbid geriatric patients].
    Zeitschrift fur Gerontologie und Geriatrie, 2009, Volume: 42, Issue:2

    Topics: Aged; Aged, 80 and over; Cognition Disorders; Female; Folic Acid; Geriatric Assessment; Germany; Homocysteine; Humans; Incidence; Male; Reproducibility of Results; Risk Assessment; Risk Factors; Sensitivity and Specificity; Statistics as Topic

2009
Serum homocysteine levels and cognitive functioning in euthymic bipolar patients.
    Journal of affective disorders, 2009, Volume: 113, Issue:3

    Topics: Adult; Age Factors; Bipolar Disorder; Cognition Disorders; Demography; Diagnostic and Statistical Manual of Mental Disorders; Dysthymic Disorder; Female; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Severity of Illness Index; Sex Factors; Vitamin B 12

2009
Malondialdehyde, carbonyl proteins and albumin-disulphide as useful oxidative markers in mild cognitive impairment and Alzheimer's disease.
    Free radical research, 2008, Volume: 42, Issue:7

    Topics: Aged; Alzheimer Disease; Biomarkers; Case-Control Studies; Cognition Disorders; Disulfides; Female; Folic Acid; Homocysteine; Humans; Male; Malondialdehyde; Middle Aged; Neopterin; Nerve Degeneration; Oxidative Stress; Protein Carbonylation; Serum Albumin; Severity of Illness Index; Vitamin B 12

2008
Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2-dependent cyclin E expression.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:11

    Topics: Adult Stem Cells; Aged; Aged, 80 and over; Animals; Cell Proliferation; Cells, Cultured; Cognition Disorders; Cyclin E; Dementia; Dentate Gyrus; Disease Models, Animal; Fibroblast Growth Factor 2; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurodegenerative Diseases; Neurons; Trigeminal Caudal Nucleus

2008
Raised homocysteine and low folate and vitamin B-12 concentrations predict cognitive decline in community-dwelling older Japanese adults.
    Clinical nutrition (Edinburgh, Scotland), 2008, Volume: 27, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Albumins; Cholesterol; Cognition Disorders; Creatinine; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Japan; Male; Middle Aged; Regression Analysis; Vitamin B 12

2008
C-reactive protein: vascular risk marker in elderly patients with mental illness.
    Dementia and geriatric cognitive disorders, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; C-Reactive Protein; Cerebrovascular Disorders; Cognition Disorders; Cystatin C; Depression; Female; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Risk Factors

2008
B vitamins for prevention of cognitive decline: insufficient evidence to justify treatment.
    JAMA, 2008, Oct-15, Volume: 300, Issue:15

    Topics: Alzheimer Disease; Cognition; Cognition Disorders; Dietary Supplements; Homocysteine; Humans; Vitamin B Complex

2008
Plasma vitamin B12 status and cerebral white-matter lesions.
    Journal of neurology, neurosurgery, and psychiatry, 2009, Volume: 80, Issue:2

    Topics: Aged; Biomarkers; Brain; Cerebral Infarction; Cerebrovascular Circulation; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Myelin Sheath; Neuropsychological Tests; Population Surveillance; Prevalence; Risk Factors; Severity of Illness Index; Vitamin B 12

2009
Homocysteine and inflammation: predictors of cognitive decline in older persons?
    Neurobiology of aging, 2010, Volume: 31, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; alpha 1-Antichymotrypsin; Biomarkers; C-Reactive Protein; Cognition; Cognition Disorders; Homocysteine; Humans; Interleukin-6; Longitudinal Studies; Male; Neuropsychological Tests; Risk Factors

2010
Homocysteine and cognitive impairment. Relation with diagnosis and neuropsychological performance.
    Dementia and geriatric cognitive disorders, 2008, Volume: 26, Issue:6

    Topics: Activities of Daily Living; Aged; Biomarkers; Cognition Disorders; Depression; Female; Homocysteine; Humans; Hypertension; Male; Memory; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychomotor Performance; Regression Analysis; Risk Factors

2008
Plasma homocysteine and risk of mild cognitive impairment.
    Dementia and geriatric cognitive disorders, 2009, Volume: 27, Issue:1

    Topics: Age of Onset; Aged; Amnesia; Apolipoproteins E; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Genotype; Homocysteine; Humans; Longitudinal Studies; Male; Risk

2009
Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency.
    The American journal of clinical nutrition, 2009, Volume: 89, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Anemia, Pernicious; Cognition Disorders; Drug Interactions; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Middle Aged; Nutrition Surveys; Nutritional Status; Odds Ratio; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency

2009
Total serum homocysteine levels do not identify cognitive dysfunction in multimorbid elderly patients.
    The journal of nutrition, health & aging, 2009, Volume: 13, Issue:2

    Topics: Aged; Aged, 80 and over; Biomarkers; Cognition Disorders; Comorbidity; Cross-Sectional Studies; Female; Geriatric Assessment; Homocysteine; Humans; Male; Nutrition Assessment; Nutritional Status; Prevalence; Psychological Tests; Risk Factors

2009
[A survey on serum homocysteine levels and cognitive function of the middle-aged and elderly persons in Tianjin city].
    Wei sheng yan jiu = Journal of hygiene research, 2008, Volume: 37, Issue:6

    Topics: Aged; Aged, 80 and over; China; Cognition; Cognition Disorders; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Sampling Studies

2008
Paraoxonase activity and dementia.
    Journal of the neurological sciences, 2009, Aug-15, Volume: 283, Issue:1-2

    Topics: Aged; Alzheimer Disease; Aryldialkylphosphatase; Cholesterol; Cholesterol, HDL; Cognition Disorders; Dementia; Dementia, Vascular; Female; Homocysteine; Humans; Immunoenzyme Techniques; Male; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Sequence Analysis, DNA; Spectrophotometry; Triglycerides

2009
Cerebral white matter lesions in patients with dementia - from MCI to severe Alzheimer's disease.
    Journal of the neurological sciences, 2009, Aug-15, Volume: 283, Issue:1-2

    Topics: Aged; Aging; Alzheimer Disease; Brain; Cognition Disorders; Disease Progression; Female; Homocysteine; Humans; Hypertension; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated

2009
High-dose B vitamin supplements and Alzheimer disease.
    JAMA, 2009, Mar-11, Volume: 301, Issue:10

    Topics: Alzheimer Disease; Cognition Disorders; Dietary Supplements; Homocysteine; Humans; Reference Values; Vitamin B Complex

2009
High-dose B vitamin supplements and Alzheimer disease.
    JAMA, 2009, Mar-11, Volume: 301, Issue:10

    Topics: Alzheimer Disease; Blood-Brain Barrier; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Vitamin B Complex

2009
Hyperhomocysteinemia, intima-media thickness and C677T MTHFR gene polymorphism: a correlation study in patients with cognitive impairment.
    Atherosclerosis, 2009, Volume: 206, Issue:1

    Topics: Aged; Aged, 80 and over; Carotid Arteries; Cognition Disorders; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Tunica Intima

2009
Homocysteine and cognitive impairment in Parkinson's disease: a biochemical, neuroimaging, and genetic study.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Jul-30, Volume: 24, Issue:10

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Aged, 80 and over; Brain; Carbon-Nitrogen Ligases; Case-Control Studies; Cognition Disorders; Cystathionine beta-Synthase; Depression; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Logistic Models; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Severity of Illness Index; Vitamin B 12; Vitamin B 6

2009
Homocysteine as a predictor of cognitive decline in Alzheimer's disease.
    International journal of geriatric psychiatry, 2010, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Cohort Studies; Female; Homocysteine; Humans; Longitudinal Studies; Male; Neuropsychological Tests; Nonlinear Dynamics; Predictive Value of Tests

2010
Methylation status and neurodegenerative markers in Parkinson disease.
    Clinical chemistry, 2009, Volume: 55, Issue:10

    Topics: Aged; alpha-Synuclein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Nerve Degeneration; Parkinson Disease; Peptide Fragments; S-Adenosylhomocysteine; S-Adenosylmethionine; Substantia Nigra; Ultrasonography; Vitamin B 6

2009
Elevated serum homocysteine level is not associated with serum C-reactive protein in patients with probable Alzheimer's disease.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:12

    Topics: Aged; Alzheimer Disease; Blood Pressure; Body Mass Index; C-Reactive Protein; Cognition Disorders; Female; Homocysteine; Humans; Male; Neuropsychological Tests; Sex Factors

2009
Homocysteine and cognitive function in geriatric depression.
    Neuropsychobiology, 2010, Volume: 61, Issue:2

    Topics: Aged; Attention; Cognition Disorders; Depression; Female; Geriatrics; Homocysteine; Humans; Immunoenzyme Techniques; Language; Male; Middle Aged; Neuropsychological Tests

2010
Oxidative LDL modification is increased in vascular dementia and is inversely associated with cognitive performance.
    Free radical research, 2010, Volume: 44, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Cognition Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Oxidation-Reduction

2010
Elevation of homocysteine levels is only partially reversed after therapy in females with eating disorders.
    Journal of neural transmission (Vienna, Austria : 1996), 2010, Volume: 117, Issue:4

    Topics: Adolescent; Adult; Anorexia Nervosa; Body Mass Index; Bulimia Nervosa; Case-Control Studies; Cognition Disorders; Female; Homocysteine; Humans; Inpatients; Neuropsychological Tests; Prospective Studies; Psychiatric Status Rating Scales; Psychometrics; Time Factors; Treatment Outcome; Young Adult

2010
Are dietary choline and betaine intakes determinants of total homocysteine concentration?
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:5

    Topics: Betaine; Cardiovascular Diseases; Choline; Cognition Disorders; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Vitamin B 12; Vitamin B 6

2010
Intrathecal methotrexate induces focal cognitive deficits and increases cerebrospinal fluid homocysteine.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 95, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Behavior, Animal; Cisterna Magna; Cognition Disorders; Disease Models, Animal; Folic Acid; Folic Acid Antagonists; Homocysteine; Inflammation Mediators; Injections, Spinal; Male; Memory Disorders; Methotrexate; Motor Activity; Neuropsychological Tests; Psychomotor Performance; Rats; Rats, Long-Evans; Recognition, Psychology; Time Factors

2010
MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:5

    Topics: Adult; Aged; Boston; Cardiovascular Diseases; Cognition Disorders; DNA Damage; Female; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Hypertension; Life Style; Male; Memory; Methionine Adenosyltransferase; Middle Aged; Puerto Rico; Stroke; Vitamin B 6

2010
Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:6

    Topics: Aged; Aging; Anemia; Anemia, Macrocytic; Blood Cell Count; Cognition; Cognition Disorders; Cystatin C; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Multivariate Analysis; Nutrition Surveys; Tetrahydrofolates; United States; Vitamin B 12 Deficiency

2010
Curcumin exerts neuroprotective effects against homocysteine intracerebroventricular injection-induced cognitive impairment and oxidative stress in rat brain.
    Journal of medicinal food, 2010, Volume: 13, Issue:4

    Topics: Animals; Brain; Cognition Disorders; Curcumin; Disease Models, Animal; Homocysteine; Humans; Infusions, Intraventricular; Learning; Male; Memory; Motor Activity; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar

2010
Vitamin B12-responsive severe leukoencephalopathy and autonomic dysfunction in a patient with "normal" serum B12 levels.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:12

    Topics: Autoantibodies; Autonomic Nervous System Diseases; Brain; Cognition Disorders; Depressive Disorder; Drug Therapy, Combination; Female; Homocysteine; Humans; Intrinsic Factor; Leukoencephalopathies; Magnetic Resonance Imaging; Mental Status Schedule; Methylmalonic Acid; Middle Aged; Neurologic Examination; Psychometrics; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D

2010
Neuroprotective effects of the polyphenolic antioxidant agent, Curcumin, against homocysteine-induced cognitive impairment and oxidative stress in the rat.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 96, Issue:4

    Topics: Animals; Antioxidants; Avoidance Learning; Cognition Disorders; Curcumin; Hippocampus; Homocysteine; Male; Malondialdehyde; Motor Activity; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar

2010
Polymorphism of MTHFR C677T, serum vitamin levels and cognition in subjects with hyperhomocysteinemia in China.
    Nutritional neuroscience, 2010, Volume: 13, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6; Vitamins

2010
Plasma homocysteine and cognition in elderly patients with dementia or other psychogeriatric diseases.
    Dementia and geriatric cognitive disorders, 2010, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Creatinine; Dementia; Diagnostic and Statistical Manual of Mental Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Neuropsychological Tests; Regression Analysis; Tomography, X-Ray Computed; Vascular Diseases; Vitamin B 12

2010
Hyperhomocysteinemia in Alzheimer dementia patients and cognitive decline after 6 months follow-up period.
    Acta neurologica Taiwanica, 2010, Volume: 19, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cognition Disorders; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Retrospective Studies

2010
[The role of homocysteine levels in the pathogenesis of cognitive disorders in patients with chronic cerebral ischemia].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2009, Volume: 109, Issue:12 Suppl 2

    Topics: Aged; Brain Ischemia; Cognition Disorders; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Severity of Illness Index

2009
Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation.
    Clinical laboratory, 2010, Volume: 56, Issue:9-10

    Topics: Aged; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neopterin; Oxidative Stress; Protein Carbonylation; Reference Values; Tryptophan; Vitamin B 12

2010
Association study of gene polymorphisms involved in vascular alterations in elderly hypertensives with subjective memory complaints.
    Dementia and geriatric cognitive disorders, 2010, Volume: 30, Issue:5

    Topics: Aged; Aged, 80 and over; Apolipoproteins E; Blood Pressure; Blood Vessels; Cognition Disorders; Cross-Sectional Studies; Data Interpretation, Statistical; Female; Genetic Association Studies; Genetic Variation; Genotype; Homocysteine; Humans; Hypertension; Inflammation; Lipid Metabolism; Magnetic Resonance Imaging; Male; Memory Disorders; Middle Aged; Multigene Family; Polymorphism, Genetic; Thrombosis

2010
Polyneuropathy and dementia in old age: common inflammatory and vascular parameters.
    Journal of neural transmission (Vienna, Austria : 1996), 2011, Volume: 118, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Cohort Studies; Dementia; Female; Folic Acid; Geriatrics; Homocysteine; Humans; Inflammation; Male; Mental Status Schedule; Neopterin; Neural Conduction; Polyneuropathies; Sural Nerve; Vascular Diseases; Vitamin B 12

2011
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and cognitive impairment: the health in men study.
    Molecular psychiatry, 2012, Volume: 17, Issue:5

    Topics: Aged, 80 and over; Aging; Case-Control Studies; Cognition Disorders; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Men's Health; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide

2012
Do the effects of APOE-ε4 on cognitive function and decline depend upon vitamin status? MacArthur Studies of Successful Aging.
    The journal of nutrition, health & aging, 2011, Volume: 15, Issue:3

    Topics: Aged; Aging; Apolipoprotein E4; Cognition; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Longitudinal Studies; Male; Nutrigenomics; Nutritional Status; United States; Vitamin B Complex

2011
Homocysteine and cerebral small vessel disease in patients with symptomatic atherosclerotic disease. The SMART-MR study.
    Atherosclerosis, 2011, Volume: 216, Issue:2

    Topics: Aged; Atherosclerosis; Brain; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Risk Factors

2011
Homocysteine effects on brain volumes mapped in 732 elderly individuals.
    Neuroreport, 2011, Jun-11, Volume: 22, Issue:8

    Topics: Aged; Alzheimer Disease; Brain; Brain Mapping; Cognition Disorders; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male

2011
Plasma homocysteine and cognitive decline in older hypertensive subjects.
    International psychogeriatrics, 2011, Volume: 23, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Cognition; Cognition Disorders; Executive Function; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hypertension; Male; Neuropsychological Tests; Risk Factors; Vitamin B 12

2011
Plasma homocysteine, brain imaging and cognition in older patients with mental illness.
    International journal of geriatric psychiatry, 2012, Volume: 27, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Brief Psychiatric Rating Scale; Cerebrovascular Disorders; Cognition Disorders; Female; Geriatric Assessment; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Regression Analysis; Tomography, X-Ray Computed

2012
Association of cognitive impairment with combinations of vitamin B₁₂-related parameters.
    Clinical chemistry, 2011, Volume: 57, Issue:10

    Topics: Aged; Biomarkers; Case-Control Studies; Cognition Disorders; Cross-Sectional Studies; Homocysteine; Humans; Methylmalonic Acid; Risk Assessment; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency

2011
Persistent cognitive deficits, induced by intrathecal methotrexate, are associated with elevated CSF concentrations of excitotoxic glutamate analogs and can be reversed by an NMDA antagonist.
    Behavioural brain research, 2011, Dec-01, Volume: 225, Issue:2

    Topics: Animals; Cognition Disorders; Dextromethorphan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Folic Acid; Glutamic Acid; Homocysteine; Humans; Injections, Spinal; Male; Memory Disorders; Methotrexate; Rats; Rats, Long-Evans; Recognition, Psychology

2011
Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study.
    Journal of internal medicine, 2012, Volume: 271, Issue:2

    Topics: Aged; Cognition Disorders; Executive Function; Female; Folic Acid; Homocysteine; Humans; Male; Memory, Episodic; Prospective Studies; Psychomotor Performance; Reaction Time; Speech; Transcobalamins

2012
[Relationship between plasma total homocysteine and mild cognitive impairment in senile patients with type 2 diabetes].
    Zhonghua yi xue za zhi, 2011, Jul-26, Volume: 91, Issue:28

    Topics: Aged; Cognition Disorders; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Homocysteine; Humans; Insulin; Insulin Resistance; Male

2011
Cognitive reserve, homocysteine, and cognition in the Bavarian School Sisters Study.
    Journal of the American Geriatrics Society, 2011, Volume: 59, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Educational Status; Female; Homocysteine; Humans

2011
Cognitive dysfunction and depression in adult kidney transplant recipients: baseline findings from the FAVORIT Ancillary Cognitive Trial (FACT).
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2012, Volume: 22, Issue:2

    Topics: Cognition Disorders; Cross-Sectional Studies; Depression; Dietary Supplements; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Kidney Transplantation; Logistic Models; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Vitamin B Deficiency; Vitamins

2012
Homocysteine and cognition in first-episode psychosis patients.
    European archives of psychiatry and clinical neuroscience, 2012, Volume: 262, Issue:7

    Topics: Adolescent; Adult; Analysis of Variance; Chi-Square Distribution; Cognition Disorders; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychotic Disorders; Retrospective Studies; Spain; Young Adult

2012
Homocysteine, grey matter and cognitive function in adults with cardiovascular disease.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Aged; Aged, 80 and over; Atrophy; Brain; Cardiovascular Diseases; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged

2012
Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults.
    The Journal of nutrition, 2012, Volume: 142, Issue:8

    Topics: Adult; Aged; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6

2012
A study of neurobehavioral, clinical psychometric, and P3 changes in vitamin B12 deficiency neurological syndrome.
    Nutritional neuroscience, 2013, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Cognition; Cognition Disorders; Event-Related Potentials, P300; Female; Follow-Up Studies; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Psychometrics; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2013
Homocysteine, progression of ventricular enlargement, and cognitive decline: the Second Manifestations of ARTerial disease-Magnetic Resonance study.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2013, Volume: 9, Issue:3

    Topics: Aged; Aging; Atherosclerosis; Atrophy; Biomarkers; Cerebral Infarction; Cerebral Ventricles; Cognition Disorders; Disease Progression; Executive Function; Female; Homocysteine; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Risk Factors

2013
Association of COMT, MTHFR, and SLC19A1(RFC-1) polymorphisms with homocysteine blood levels and cognitive impairment in Parkinson's disease.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:10

    Topics: Catechol O-Methyltransferase; Cognition Disorders; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Parkinson Disease; Polymorphism, Genetic; Reduced Folate Carrier Protein; Vitamin B 12

2012
Effects of resveratrol on blood homocysteine level, on homocysteine induced oxidative stress, apoptosis and cognitive dysfunctions in rats.
    Brain research, 2012, Nov-12, Volume: 1484

    Topics: Animals; Antioxidants; Aorta; Apoptosis; Cognition Disorders; DNA Fragmentation; Homocysteine; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Maze Learning; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Wistar; Resveratrol; Stilbenes

2012
Relationship of cognitive function with B vitamin status, homocysteine, and tissue factor pathway inhibitor in cognitively impaired elderly: a cross-sectional survey.
    Journal of Alzheimer's disease : JAD, 2013, Volume: 33, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Mental Status Schedule; Neuropsychological Tests; Vitamin B 12; Vitamin B 12 Deficiency

2013
Cognitive function in an elderly population: interaction between vitamin B12 status, depression, and apolipoprotein E ε4: the Hordaland Homocysteine Study.
    Psychosomatic medicine, 2013, Volume: 75, Issue:1

    Topics: Aged; Apolipoprotein E4; Cognition; Cognition Disorders; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Neuropsychological Tests; Norway; Regression Analysis; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency

2013
Low and high homocysteine are associated with mortality independent of B group vitamins but interactive with cognitive status in a free-living elderly cohort.
    Nutrition research (New York, N.Y.), 2012, Volume: 32, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Biomarkers; Cause of Death; Cognition; Cognition Disorders; Diet; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mortality, Premature; Proportional Hazards Models; Smoking; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B Complex; Vitamin B Deficiency

2012
Associations between elevated homocysteine, cognitive impairment, and reduced white matter volume in healthy old adults.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2013, Volume: 21, Issue:2

    Topics: Age Factors; Aged; Asian People; Brain; Cardiovascular Diseases; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Organ Size; Singapore; Vitamin B 12

2013
Plasma homocysteine and cognitive impairment in an older British African-Caribbean population.
    Journal of the American Geriatrics Society, 2002, Volume: 50, Issue:7

    Topics: Aged; Black or African American; Black People; Caribbean Region; Chi-Square Distribution; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Logistic Models; London; Male; Middle Aged; Sampling Studies; Socioeconomic Factors; White People

2002
Optimal use of markers for cobalamin and folate status in a psychogeriatric population.
    International journal of geriatric psychiatry, 2002, Volume: 17, Issue:10

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12

2002
Homocysteine, white matter hyperintensities, and cognition in healthy elderly people.
    Annals of neurology, 2003, Volume: 53, Issue:2

    Topics: Aged; Brain; Cognition; Cognition Disorders; Cross-Sectional Studies; Dementia; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers; Risk Factors

2003
Homocysteine as a risk factor for cognitive impairment in stroke patients.
    Dementia and geriatric cognitive disorders, 2003, Volume: 15, Issue:3

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognition Disorders; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Risk Factors; Stroke

2003
[Serum markers in relation to cognitive functioning in an aging population: results of the Maastricht Aging Study (MAAS)].
    Tijdschrift voor gerontologie en geriatrie, 2003, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Biomarkers; C-Reactive Protein; Cholesterol; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Haptoglobins; Homocysteine; Humans; Lanosterol; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Psychomotor Performance

2003
Folate deficiency is a common finding in psychogeriatric patients.
    Aging clinical and experimental research, 2002, Volume: 14, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Regression Analysis; Vitamin B 12

2002
Hyperhomocysteinemia and vitamin score: correlations with silent brain ischemic lesions and brain atrophy.
    Dementia and geriatric cognitive disorders, 2003, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Atrophy; Brain; Brain Ischemia; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 6; Vitamins

2003
Homocysteine: a marker for cognitive performance? A longitudinal follow-up study.
    The journal of nutrition, health & aging, 2003, Volume: 7, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Cognition; Cognition Disorders; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Psychomotor Performance; Risk Factors; Vitamin B 12

2003
Homocysteine, apolipoproteine E and methylenetetrahydrofolate reductase in Alzheimer's disease and mild cognitive impairment.
    Dementia and geriatric cognitive disorders, 2003, Volume: 16, Issue:2

    Topics: Aged; Alzheimer Disease; Apolipoproteins E; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12

2003
Vitamins, homocysteine, and cognition.
    The American journal of clinical nutrition, 2003, Volume: 78, Issue:3

    Topics: Biomarkers; Cognition Disorders; Educational Status; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 Deficiency

2003
Homocysteine and cognitive function in the Sacramento Area Latino Study on Aging.
    The American journal of clinical nutrition, 2003, Volume: 78, Issue:3

    Topics: Age Factors; Aged; Biomarkers; California; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Educational Status; Female; Hispanic or Latino; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Predictive Value of Tests; Risk Factors; Sex Factors; Vitamin B 12

2003
The S-adenosyl homocysteine hydrolase inhibitor 3-deaza-adenosine prevents oxidative damage and cognitive impairment following folate and vitamin E deprivation in a murine model of age-related, oxidative stress-induced neurodegeneration.
    Neuromolecular medicine, 2004, Volume: 5, Issue:2

    Topics: Adenosylhomocysteinase; Animals; Apolipoproteins E; Brain; Brain Chemistry; Cognition Disorders; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Female; Folic Acid Deficiency; Homocysteine; Male; Methionine; Mice; Mice, Knockout; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Tubercidin; Vitamin E Deficiency

2004
Cerebrospinal fluid tau protein and periventricular white matter lesions in patients with mild cognitive impairment: implications for 2 major pathways.
    Archives of neurology, 2004, Volume: 61, Issue:5

    Topics: Aged; Alzheimer Disease; Apolipoproteins E; Biomarkers; Brain; Cognition Disorders; Dementia; Disease Progression; Female; Follow-Up Studies; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Prospective Studies; Radiography; Risk Factors; tau Proteins

2004
Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons.
    Journal of neuroscience research, 2004, Jul-01, Volume: 77, Issue:1

    Topics: Alzheimer Disease; Amidohydrolases; Animals; Antioxidants; Arginine; Brain; Cells, Cultured; Cognition Disorders; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Feedback, Physiological; Homocysteine; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Proline; Rats; Thiocarbamates; Up-Regulation

2004
Homocysteine, Alzheimer genes and proteins, and measures of cognition and depression in older men.
    Journal of Alzheimer's disease : JAD, 2004, Volume: 6, Issue:3

    Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Depression; Gene Expression; Homocysteine; Humans; Male; Neuropsychological Tests; Point Mutation; Polymerase Chain Reaction; Severity of Illness Index; Surveys and Questionnaires; Tetrahydrofolates

2004
Elevated plasma homocysteine level in patients with Parkinson disease: motor, affective, and cognitive associations.
    Archives of neurology, 2004, Volume: 61, Issue:6

    Topics: Aged; Cognition Disorders; Depression; Female; Homocysteine; Humans; Male; Middle Aged; Mood Disorders; Motor Skills Disorders; Parkinson Disease; Prospective Studies; Psychiatric Status Rating Scales

2004
Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cognition Disorders; Cross-Sectional Studies; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Risk Factors; Switzerland; Vitamin B 12

2004
Total homocysteine and cognition in a tri-ethnic cohort: the Northern Manhattan Study.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adult; Age Factors; Aged; Apolipoprotein E4; Apolipoproteins E; Black or African American; Cognition; Cognition Disorders; Cohort Studies; Ethnicity; Fasting; Female; Hispanic or Latino; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; New York City; Psychological Tests; Risk Factors; Socioeconomic Factors; Vitamin B 12 Deficiency; White People

2004
Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life.
    Neurobiology of aging, 2005, Volume: 26, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Anxiety; Chi-Square Distribution; Cognition Disorders; Cross-Sectional Studies; Depression; DNA Mutational Analysis; Female; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Personality Inventory; Pteroylpolyglutamic Acids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vitamin B 12

2005
Blood lead is a predictor of homocysteine levels in a population-based study of older adults.
    Environmental health perspectives, 2005, Volume: 113, Issue:1

    Topics: Aged; Cardiovascular Diseases; Central Nervous System; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Lead; Longitudinal Studies; Male; Middle Aged

2005
Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
    The American journal of medicine, 2005, Volume: 118, Issue:2

    Topics: Aged; Aging; Alzheimer Disease; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Longitudinal Studies; Male; Risk Factors; Vitamin B 12; Vitamin B 6

2005
Low blood pressure is a better predictor of cognitive deficits than the apolipoprotein e4 allele in the oldest old.
    Acta neurologica Scandinavica, 2005, Volume: 111, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Apolipoprotein E4; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Hypotension; Male; Mental Status Schedule; Predictive Value of Tests; Prognosis; Sex Factors

2005
Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment.
    Neurology, 2005, Apr-26, Volume: 64, Issue:8

    Topics: Adult; Anticoagulants; Betaine; Cognition Disorders; Confusion; Disease Progression; Drug Therapy, Combination; Folic Acid; Frontal Lobe; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Remission Induction; Seizures; Treatment Outcome; Vitamin B 12; Vitamin B 6

2005
Short-term cognition deficits during early alcohol withdrawal are associated with elevated plasma homocysteine levels in patients with alcoholism.
    Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:3

    Topics: Adult; Alcohol-Induced Disorders, Nervous System; Alcoholism; Biomarkers; Brain; Brain Chemistry; Central Nervous System Depressants; Cognition Disorders; Ethanol; Female; Homocysteine; Humans; Male; Middle Aged; Nerve Tissue Proteins; Predictive Value of Tests; Substance Withdrawal Syndrome; Time Factors; Up-Regulation

2006
Subjective memory complaints with and without objective memory impairment: relationship with risk factors for dementia.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Anxiety; Apolipoprotein E4; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Risk Factors; Self-Assessment; Sick Role; Western Australia

2005
The relation between homocysteine levels and development of Alzheimer's disease in mild cognitive impairment patients.
    Dementia and geriatric cognitive disorders, 2005, Volume: 20, Issue:4

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Creatinine; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Sex Characteristics; Thyrotropin; Vitamin B 12; Vitamins

2005
Homocysteine and cognitive performance in the Framingham offspring study: age is important.
    American journal of epidemiology, 2005, Oct-01, Volume: 162, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Pyridoxine; Regression Analysis; Risk Factors; Vitamin B 12

2005
Hyperhomocysteinemia and cognitive function: more than just a casual link?
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:3

    Topics: Aging; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors

2005
High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Diet; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2005
Food-cobalamin malabsorption in elderly patients: clinical manifestations and treatment.
    The American journal of medicine, 2005, Volume: 118, Issue:10

    Topics: Aged; Aged, 80 and over; Asthenia; Cognition Disorders; Cohort Studies; Confusion; Edema; Erythrocyte Indices; Female; Follow-Up Studies; Gastritis, Atrophic; Hematologic Diseases; Hemoglobins; Homocysteine; Humans; Jaundice; Malabsorption Syndromes; Male; Paresthesia; Polyneuropathies; Reflex, Abnormal; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency

2005
Homocysteine and B vitamins in mild cognitive impairment and dementia.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:10

    Topics: Aged; Cognition Disorders; Dementia; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12

2005
Homocysteine, type 2 diabetes mellitus, and cognitive performance: The Maine-Syracuse Study.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:10

    Topics: Cognition; Cognition Disorders; Diabetes Mellitus, Type 2; Homocysteine; Humans; Maine; Middle Aged; New York

2005
Plasma homocysteine levels in L-dopa-treated Parkinson's disease patients with cognitive dysfunctions.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:10

    Topics: Aged; Case-Control Studies; Cognition Disorders; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease

2005
Cognitive impairment and its association with homocysteine plasma levels in females with eating disorders - findings from the HEaD-study.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Anorexia Nervosa; Brain; Brain Chemistry; Bulimia Nervosa; Case-Control Studies; Cognition Disorders; Feeding and Eating Disorders; Female; Homocysteine; Humans; Long-Term Potentiation; Memory; Memory Disorders; Middle Aged; Neuropsychological Tests; Prospective Studies; Receptors, N-Methyl-D-Aspartate; Sex Factors; Synaptic Transmission; Up-Regulation

2005
Hyperhomocysteinemia is associated with volumetric white matter change in patients with small vessel disease.
    Journal of neurology, 2006, Volume: 253, Issue:4

    Topics: Aged; Brain; Cerebrovascular Disorders; Cognition Disorders; Cohort Studies; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychometrics; Regression Analysis; Risk Factors; Stroke; Vitamin B 12

2006
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.
    Neurology, 2005, Nov-08, Volume: 65, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12

2005
Homocysteine and cognition--no longer a hypothesis?
    Medical hypotheses, 2006, Volume: 66, Issue:3

    Topics: Aged; Alzheimer Disease; Cognition; Cognition Disorders; Homocysteine; Humans; Methionine; Models, Biological; Models, Theoretical; Neurodegenerative Diseases; Vitamin B 12; Vitamins

2006
Low folate status is associated with impaired cognitive function and dementia in the Sacramento Area Latino Study on Aging.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; California; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Dementia; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Regression Analysis; Vitamin B Complex

2005
Plasma homocysteine and vascular disease in psychogeriatric patients.
    Dementia and geriatric cognitive disorders, 2006, Volume: 21, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Confusion; Dementia; Dementia, Vascular; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Middle Aged; Natriuretic Peptide, Brain; Neuropsychological Tests; Peptide Fragments; Reference Values; Risk Factors; Vitamin B 12

2006
Angiotensin converting enzyme (ACE) inhibitors modulate the rate of progression of amnestic mild cognitive impairment.
    International journal of geriatric psychiatry, 2006, Volume: 21, Issue:6

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Cognition Disorders; Dementia; Disease Progression; Educational Status; Female; Homocysteine; Humans; Male; Memory Disorders; Neuropsychological Tests; Prognosis; Psychiatric Status Rating Scales; Risk Factors

2006
Homocysteine level and cognitive function in patients with arterial disease: the second manifestations of ARTerial Disease Study.
    Journal of the American Geriatrics Society, 2006, Volume: 54, Issue:4

    Topics: Adult; Aged; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Risk Factors; Vascular Diseases

2006
Brain volume changes in CADASIL: a serial MRI study in pure subcortical ischemic vascular disease.
    Neurology, 2006, May-23, Volume: 66, Issue:10

    Topics: Adult; Atrophy; Brain; CADASIL; Cognition Disorders; Comorbidity; Disease Progression; Female; Fibrinogen; Follow-Up Studies; Homocysteine; Humans; Hypercholesterolemia; Hypertension; Magnetic Resonance Imaging; Male; Middle Aged; Organ Size; Risk Factors; Smoking

2006
C-reactive protein, but not homocysteine, is related to cognitive dysfunction in older adults with cardiovascular disease.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2006, Volume: 13, Issue:5

    Topics: Aged; Aged, 80 and over; C-Reactive Protein; Cardiovascular Diseases; Cognition Disorders; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Prospective Studies

2006
Relation between vascular risk factors and cognition at age 75.
    Acta neurologica Scandinavica, 2006, Volume: 114, Issue:2

    Topics: Aged; Aging; Alzheimer Disease; Austria; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Cognition Disorders; Cohort Studies; Comorbidity; Cross-Sectional Studies; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperlipidemias; Hypertension; Lipoproteins; Male; Neuropsychological Tests; Risk Factors; Smoking; Statistics as Topic; Triglycerides

2006
The relationship between homocysteine, cognition and stroke subtypes in acute stroke.
    Journal of the neurological sciences, 2006, Dec-01, Volume: 250, Issue:1-2

    Topics: Acute Disease; Aged; Brain; Brain Infarction; Cerebral Arteries; Cerebrovascular Circulation; Cognition; Cognition Disorders; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Predictive Value of Tests; Statistics as Topic; Stroke; Up-Regulation

2006
Plasma homocysteine, cobalamin/folate status, and vascular disease in a large population of psychogeriatric patients.
    Dementia and geriatric cognitive disorders, 2006, Volume: 22, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Depressive Disorder; Female; Folic Acid; Hematocrit; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Nutritional Status; Population; Sweden; Vascular Diseases; Vitamin B 12

2006
Homocysteine lowering and cognitive performance.
    The New England journal of medicine, 2006, Sep-28, Volume: 355, Issue:13

    Topics: Aged; Cognition; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex

2006
Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:1

    Topics: Cognition Disorders; Dose-Response Relationship, Drug; Folic Acid; Food, Fortified; Homocysteine; Humans; Immune System; Neoplasms; Nutrition Policy; Vitamin B 12; Vitamin B Complex

2007
Is dietary intake of folate too low?
    Lancet (London, England), 2007, Jan-20, Volume: 369, Issue:9557

    Topics: Aged; Cognition Disorders; Diet; Folic Acid; Folic Acid Deficiency; Food Analysis; Homocysteine; Humans; Middle Aged; Nutrition Policy; Nutritional Status; Randomized Controlled Trials as Topic

2007
Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; California; Cognition Disorders; Dementia; Disease Susceptibility; Female; Folic Acid; Health Surveys; Hispanic or Latino; Homocysteine; Humans; Incidence; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12

2007
Homocysteine and electroencephalographic rhythms in Alzheimer disease: a multicentric study.
    Neuroscience, 2007, Mar-30, Volume: 145, Issue:3

    Topics: Aged; Alzheimer Disease; Biomarkers; Brain; Cognition Disorders; Electroencephalography; Female; Homocysteine; Humans; Male

2007
Homocysteine and post-stroke cognitive decline.
    Age and ageing, 2007, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Attention; Cognition; Cognition Disorders; Cohort Studies; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Logistic Models; Predictive Value of Tests; Recovery of Function; Stroke; Time Factors; Verbal Behavior

2007
Plasma homocysteine is elevated in elderly patients with memory complaints and vascular disease.
    Dementia and geriatric cognitive disorders, 2007, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Brain; Cognition Disorders; Female; Homocysteine; Humans; Male; Memory Disorders; Middle Aged; Reference Values; Vascular Diseases

2007
Homocysteinemia may be equally important to stroke subtype in predicting cognition impairment.
    Journal of the neurological sciences, 2007, Sep-15, Volume: 260, Issue:1-2

    Topics: Biomarkers; Cerebral Arteries; Cerebrovascular Disorders; Cognition Disorders; Homocysteine; Homocystinuria; Humans; Models, Neurological; Predictive Value of Tests; Regression Analysis; Risk Factors; Stroke

2007
Neuropsychological correlates of homocysteine levels in euthymic bipolar patients.
    Journal of affective disorders, 2008, Volume: 105, Issue:1-3

    Topics: Adolescent; Adult; Bipolar Disorder; Cognition; Cognition Disorders; Dysthymic Disorder; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Severity of Illness Index; Vitamin B 12

2008
Association between Helicobacter pylori infection and mild cognitive impairment.
    European journal of neurology, 2007, Volume: 14, Issue:9

    Topics: Aged; Aged, 80 and over; Chi-Square Distribution; Cognition Disorders; Confidence Intervals; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Immunoglobulin G; Male; Middle Aged; Prospective Studies

2007
Helicobacter pylori may be involved in cognitive impairment and dementia development through induction of atrophic gastritis, vitamin B-12 folate deficiency, and hyperhomocysteinemia sequence.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Dementia; Folic Acid Deficiency; Gastritis, Atrophic; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency

2007
Low vitamin B-12 status and risk of cognitive decline in older adults.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:5

    Topics: Aged; Aged, 80 and over; Cognition Disorders; Cohort Studies; Female; Homocysteine; Humans; Longitudinal Studies; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency

2007
Association of diabetes, homocysteine, and HDL with cognition and disability after stroke.
    Neurology, 2007, Nov-27, Volume: 69, Issue:22

    Topics: Aged; Brief Psychiatric Rating Scale; Cholesterol, HDL; Cognition; Cognition Disorders; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Stroke

2007
Plasma aminothiol compounds, but not serum tumor necrosis factor receptor II and soluble receptor for advanced glycation end products, are related to the cognitive impairment in Alzheimer's disease and mild cognitive impairment patients.
    Neuroimmunomodulation, 2007, Volume: 14, Issue:3-4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Cysteine; Down-Regulation; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Tumor Necrosis Factor, Type II; Sulfhydryl Compounds; Up-Regulation

2007
Hyperhomocysteinemia is associated with cognitive impairment in multiple sclerosis.
    Journal of neurology, 2008, Volume: 255, Issue:1

    Topics: Age of Onset; Brain; Cognition Disorders; Disability Evaluation; Disease Progression; Folic Acid; Homocysteine; Hyperhomocysteinemia; Multiple Sclerosis; Multivariate Analysis; Neuropsychological Tests; Predictive Value of Tests; Up-Regulation; Vitamin B 12 Deficiency

2008
Homocysteine and C-reactive protein are not markers of cognitive impairment in patients with major cardiovascular disease.
    Dementia and geriatric cognitive disorders, 2008, Volume: 25, Issue:4

    Topics: Aged; Biomarkers; C-Reactive Protein; Cognition Disorders; Coronary Artery Bypass; Coronary Artery Disease; Female; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Prevalence; Risk Factors

2008
The impact of homocysteine levels on cognition in euthymic bipolar patients: a cross-sectional study.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:6

    Topics: Adult; Affect; Bipolar Disorder; Body Mass Index; Cognition Disorders; Cross-Sectional Studies; Diagnostic and Statistical Manual of Mental Disorders; Female; Homocysteine; Humans; Male; Severity of Illness Index; Wechsler Scales

2008
Homocysteine, folate and cognition in a large community-based sample of elderly people--the 3C Dijon Study.
    Neuroepidemiology, 2008, Volume: 30, Issue:4

    Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; France; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Prospective Studies; Residence Characteristics; Risk Factors; Urban Health

2008
The effect of vitamin B12 deficiency on older veterans and its relationship to health.
    Journal of the American Geriatrics Society, 1998, Volume: 46, Issue:10

    Topics: Aged; Aged, 80 and over; Alcohol Drinking; Analysis of Variance; Cognition Disorders; Cross-Sectional Studies; Educational Status; Female; Geriatric Assessment; Homocysteine; Humans; Income; Male; Methylmalonic Acid; Oklahoma; Reproducibility of Results; Veterans; Vitamin B 12; Vitamin B 12 Deficiency

1998
Total homocysteine and cognitive decline in a community-based sample of elderly subjects: the Rotterdam Study.
    American journal of epidemiology, 1999, Aug-01, Volume: 150, Issue:3

    Topics: Aged; Cognition Disorders; Dementia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Netherlands; Prospective Studies; Random Allocation; Risk Factors; Sensitivity and Specificity

1999
Thermolabile methylenetetrahydrofolate reductase gene and the risk of cognitive impairment in those over 85.
    Journal of neurology, neurosurgery, and psychiatry, 1999, Volume: 67, Issue:4

    Topics: Aged; Aged, 80 and over; Cognition Disorders; Female; Follow-Up Studies; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Risk Factors; Temperature

1999
Vascular involvement in cognitive decline and dementia. Epidemiologic evidence from the Rotterdam Study and the Rotterdam Scan Study.
    Annals of the New York Academy of Sciences, 2000, Volume: 903

    Topics: Aged; Alzheimer Disease; Arteriosclerosis; Atrial Fibrillation; Brain; Cerebrovascular Circulation; Cognition Disorders; Cross-Sectional Studies; Dementia; Diabetes Mellitus; Female; Homocysteine; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Netherlands; Prospective Studies; Risk Factors; Smoking

2000
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment.
    Mechanisms of ageing and development, 2000, Dec-20, Volume: 121, Issue:1-3

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Dementia; Dementia, Vascular; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Male; Pyridoxine; Reference Values; Vitamin B 12

2000
Hyperhomocysteinemia in dementia.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:12

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Pilot Projects; Reference Values; Regression Analysis; Risk Factors; Vitamin B 12

2000
One-carbon metabolism and other biochemical correlates of cognitive impairment as visualized by principal component analysis.
    Journal of geriatric psychiatry and neurology, 2001,Fall, Volume: 14, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Atrophy; Brain; Cognition Disorders; Dementia, Vascular; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Reference Values; Severity of Illness Index; tau Proteins; Vitamin B 12

2001
[Homocysteine--not a risk factor but a marker of deficiency and risk].
    Lakartidningen, 2001, Aug-29, Volume: 98, Issue:35

    Topics: Aged; Biomarkers; Cognition Disorders; Homocysteine; Humans; Risk Factors; Vitamin B 12 Deficiency

2001
Total homocysteine and cognitive deterioration in people with type 2 diabetes.
    Diabetes research and clinical practice, 2002, Volume: 55, Issue:3

    Topics: Aged; Albuminuria; Cholesterol; Cognition; Cognition Disorders; Diabetes Mellitus, Type 2; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Lipoproteins; Male; Middle Aged; Triglycerides; Vitamin B 12

2002
Plasma homocysteine in vascular disease and in nonvascular dementia of depressed elderly people.
    Acta psychiatrica Scandinavica, 1992, Volume: 86, Issue:5

    Topics: Adult; Age Factors; Aged; Cognition Disorders; Cross-Sectional Studies; Dementia; Depressive Disorder; Female; Homocysteine; Humans; Male; Vascular Diseases

1992