homocysteine and Cleft Spine

homocysteine has been researched along with Cleft Spine in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (38.46)	18.2507
2000's	11 (42.31)	29.6817
2010's	5 (19.23)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dai, XL; Jin, MH; Liu, GC; Mi, NN; Ren, XY; Wang, J; Wang, SQ; Zhang, J	1
Caredda, E; Cennamo, M; Del Gado, R; Iossa, AC; Montaldo, L; Montaldo, P	1
Acosta, D; Cadenas-Benitez, NM; Cerrillos, L; Gomez de Terreros, I; Gonzalez-Meneses, A; Neth, O; Praena-Fernandez, JM; Yanes-Sosa, F; Ybot-González, P	1
Baido, SF; Blair, IA; Mitchell, LE; Stanislawska-Sachadyn, A; Summers, CM; Von Feldt, JM; Whitehead, AS	1
Carmichael, SL; Gilbert, DA; Hardin, J; Hoffmann, TJ; Lammer, EJ; Lazaruk, K; Lipzen, A; Marini, NJ; Pennacchio, LA; Rine, J; Shaw, GM; Stein, JB; Witte, JS; Wright, C	1
Barbaux, S; Doolin, MT; Hoess, K; McDonnell, M; Mitchell, LE; Whitehead, AS	1
Brunoni, D; D'Almeida, V; de Lima, FT; de Oliveira, AC; Perez, AB; Vergani, N	1
Ballman, KV; Berger, PB; Ellison, RC; Jacques, PF; Rozen, R; Spotila, LD	1
Finnell, RH; Lammer, EJ; Laurent, C; Shaw, GM; Volcik, KA; Zhu, H	1
Cook, M; Hoess, K; Jensen, LE; Mitchell, LE; Thorn, CF; Wall, AM; Whitehead, AS	1
Gooskens, RH; Groenen, PM; Peer, PG; Steegers-Theunissen, RP; van Rooij, IA; Zielhuis, GA	1
Blom, HJ; den Heijer, M; Franke, B; Gellekink, H; Heil, SG; Nguyen, U; van der Linden, IJ; Vloet, S	1
Blom, HJ; den Heyer, M; Eskes, TK; Frosst, P; Mariman, EC; Rozen, R; Steegers-Theunissen, RP; Trijbels, FJ; van den Heuvel, LP; van der Put, NM	1
Adams, MJ; Dickinson, CM; Oakley, GP	1
Blom, HJ; den Heyer, M; Eskes, TK; Mariman, EC; Steegers-Theunissen, RP; Trijbels, FJ; van den Heuvel, LP; van der Put, NM	1
Blom, HJ; De Graaf-Hess, A; Eskes, TK; Mariman, EC; Smeitink, JA; Steegers-Theunissen, RP; Thomas, CM; Trijbels, FJ; van der Put, NM	1
Bjørke-Monsen, AL; Refsum, H; Schneede, J; Ueland, PM; Vollset, SE	1
Eskes, TK	2
Ermert, A; Koch, MC; Schröter, B; Stegmann, K; Ziegler, A	1
Christensen, B; Rozen, R; Sibani, S; Tran, P; Weisberg, I	1
Christensen, B; Gravel, RA; Leclerc, D; Platt, R; Rozen, R; Wilson, A; Wu, Q; Yang, H	1
Akar, E; Akar, N; Arsan, S; Deda, G	1
Brouwer, IA; Eskes, TK; Gaytant, MA; Hautvast, JG; Steegers-Theunissen, RP; Thomas, CM; van der Put, NM; van Dusseldorp, M	1
Gorman, C	1

Reviews

3 review(s) available for homocysteine and Cleft Spine

Article	Year
More folic acid for everyone, now. The Journal of nutrition, 1996, Volume: 126, Issue:3 Topics: Adult; Aged; Anencephaly; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Infant, Newborn; Male; Pregnancy; Risk Factors; Spinal Dysraphism; United States; Vitamin B 12; Vitamin B 12 Deficiency	1996
Neural tube defects, vitamins and homocysteine. European journal of pediatrics, 1998, Volume: 157 Suppl 2 Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Rats; Spinal Dysraphism	1998
From birth to conception. Open or closed. European journal of obstetrics, gynecology, and reproductive biology, 1998, Volume: 78, Issue:2 Topics: Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Netherlands; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Spinal Dysraphism	1998

Trials

1 trial(s) available for homocysteine and Cleft Spine

Article	Year
Homocysteine metabolism and effects of folic acid supplementation in patients affected with spina bifida. Neuropediatrics, 2000, Volume: 31, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Case-Control Studies; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Middle Aged; Spinal Dysraphism; Treatment Outcome	2000

Other Studies

22 other study(ies) available for homocysteine and Cleft Spine

Article	Year
An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida. Neuromolecular medicine, 2017, Volume: 19, Issue:2-3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Sequence; Cells, Cultured; Exons; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylation; Models, Molecular; Pregnancy; Pregnancy Complications; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Deletion; Spinal Dysraphism; Young Adult	2017
Small renal size in newborns with spina bifida: possible causes. Clinical and experimental nephrology, 2014, Volume: 18, Issue:1 Topics: Biomarkers; Case-Control Studies; Creatinine; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Insulin-Like Growth Factor I; Kidney; Organ Size; Spinal Dysraphism; Ultrasonography	2014
Association of neural tube defects in children of mothers with MTHFR 677TT genotype and abnormal carbohydrate metabolism risk: a case-control study. Genetics and molecular research : GMR, 2014, Mar-26, Volume: 13, Issue:1 Topics: Adult; Alleles; Carbohydrate Metabolism; Case-Control Studies; Female; Genetic Association Studies; Genotype; Homocysteine; Humans; Incidence; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Neural Tube Defects; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Spinal Dysraphism; Young Adult	2014
Genetic and lifestyle variables associated with homocysteine concentrations and the distribution of folate derivatives in healthy premenopausal women. Birth defects research. Part A, Clinical and molecular teratology, 2010, Volume: 88, Issue:8 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Black or African American; Child; Child, Preschool; Dietary Supplements; Erythrocytes; Female; Genetic Association Studies; Homocysteine; Humans; Infant; Life Style; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Pregnancy; Premenopause; Spinal Dysraphism; Tetrahydrofolates; Thymidylate Synthase; Vitamins; White People; Young Adult	2010
A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis. PloS one, 2011, Volume: 6, Issue:11 Topics: Alleles; Case-Control Studies; Folic Acid; Gene Expression Profiling; Genetic Predisposition to Disease; Hispanic or Latino; Homocysteine; Humans; Infant, Newborn; Metabolic Networks and Pathways; Models, Genetic; Mutation; Purines; Risk Factors; Spinal Dysraphism; White People	2011
Maternal genetic effects, exerted by genes involved in homocysteine remethylation, influence the risk of spina bifida. American journal of human genetics, 2002, Volume: 71, Issue:5 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Algorithms; Computational Biology; Ferredoxin-NADP Reductase; Homocysteine; Linear Models; Methylation; Polymorphism, Single Nucleotide; Risk Factors; Spinal Dysraphism	2002
Folate delivers head-to-toe health advantages. The B vitamin that benefits unborn babies may also protect the hearts and minds (and colons) of adults. Health news (Waltham, Mass.), 2002, Volume: 8, Issue:12 Topics: Alzheimer Disease; Anencephaly; Colonic Neoplasms; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Male; Pregnancy; Spinal Dysraphism; Stroke	2002
Methylenetetrahydrofolate reductase (MTHFR): incidence of mutations C677T and A1298C in Brazilian population and its correlation with plasma homocysteine levels in spina bifida. American journal of medical genetics. Part A, 2003, May-15, Volume: 119A, Issue:1 Topics: Brazil; Child, Preschool; Female; Gene Frequency; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Spinal Dysraphism	2003
Age dependence of the influence of methylenetetrahydrofolate reductase genotype on plasma homocysteine level. American journal of epidemiology, 2003, Nov-01, Volume: 158, Issue:9 Topics: Adolescent; Adult; Age Factors; Aged; Cardiovascular Diseases; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Spinal Dysraphism	2003
Associations between polymorphisms within the thymidylate synthase gene and spina bifida. Birth defects research. Part A, Clinical and molecular teratology, 2003, Volume: 67, Issue:11 Topics: 3' Untranslated Regions; Case-Control Studies; DNA Primers; Exons; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Infant, Newborn; Models, Biological; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Spinal Dysraphism; Thymidylate Synthase	2003
A common ABCC2 promoter polymorphism is not a determinant of the risk of spina bifida. Birth defects research. Part A, Clinical and molecular teratology, 2004, Volume: 70, Issue:6 Topics: ATP-Binding Cassette Transporters; Folic Acid; Genetic Variation; Homocysteine; Humans; Likelihood Functions; Linear Models; Multidrug Resistance-Associated Protein 2; Neural Tube Defects; Pedigree; Polymorphism, Genetic; Promoter Regions, Genetic; Retrospective Studies; Risk Factors; Spinal Dysraphism	2004
Marginal maternal vitamin B12 status increases the risk of offspring with spina bifida. American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:1 Topics: Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Pregnancy; Risk Assessment; Risk Factors; Spinal Dysraphism; Vitamin B 12; Vitamin B 6	2004
Variation and expression of dihydrofolate reductase (DHFR) in relation to spina bifida. Molecular genetics and metabolism, 2007, Volume: 91, Issue:1 Topics: 5' Untranslated Regions; Adolescent; Adult; Case-Control Studies; Cell Line; Female; Genetic Variation; Homocysteine; Humans; Male; Middle Aged; Population Groups; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Sequence Deletion; Spinal Dysraphism; Tetrahydrofolate Dehydrogenase	2007
Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida. Lancet (London, England), 1995, Oct-21, Volume: 346, Issue:8982 Topics: Adult; Female; Folic Acid; Gene Frequency; Homocysteine; Homozygote; Humans; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors; Spinal Dysraphism	1995
Decreased methylene tetrahydrofolate reductase activity due to the 677C-->T mutation in families with spina bifida offspring. Journal of molecular medicine (Berlin, Germany), 1996, Volume: 74, Issue:11 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Aged; Child; Cysteine; Female; Folic Acid; Genetic Linkage; Genotype; Homocysteine; Homozygote; Humans; Lod Score; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Netherlands; Oxidoreductases; Point Mutation; Risk Factors; Spinal Dysraphism; Vitamin B 12	1996
Altered folate and vitamin B12 metabolism in families with spina bifida offspring. QJM : monthly journal of the Association of Physicians, 1997, Volume: 90, Issue:8 Topics: Adolescent; Adult; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk; Spinal Dysraphism; Statistics, Nonparametric; Vitamin B 12	1997
Elevated plasma total homocysteine and C677T mutation of the methylenetetrahydrofolate reductase gene in patients with spina bifida. QJM : monthly journal of the Association of Physicians, 1997, Volume: 90, Issue:9 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adolescent; Child; Child, Preschool; Female; Genotype; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Odds Ratio; Oxidoreductases; Regression Analysis; Risk; Spinal Dysraphism	1997
Evaluation of the MTHFR C677T allele and the MTHFR gene locus in a German spina bifida population. European journal of pediatrics, 1998, Volume: 157, Issue:6 Topics: Alleles; Case-Control Studies; Family; Female; Folic Acid; Genetic Linkage; Germany; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Spinal Dysraphism	1998
A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Molecular genetics and metabolism, 1998, Volume: 64, Issue:3 Topics: Adult; Black People; Child; Female; Folic Acid; Gene Frequency; Genetic Variation; Homocysteine; Homocystinuria; Homozygote; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Protein Denaturation; Spinal Dysraphism	1998
A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida. Molecular genetics and metabolism, 1999, Volume: 67, Issue:4 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Substitution; Child; Child, Preschool; Deoxyribonucleases, Type II Site-Specific; DNA; Family Health; Female; Gene Frequency; Genetic Variation; Genotype; Homocysteine; Humans; Isoleucine; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Regression Analysis; Risk Factors; Spinal Dysraphism; Vitamin B 12	1999
Spina bifida and common mutations at the homocysteine metabolism pathway. Clinical genetics, 2000, Volume: 57, Issue:3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Case-Control Studies; Cystathionine beta-Synthase; Female; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Risk; Spinal Dysraphism; Vitamin B 12	2000
In praise of folic acid. Time, 2002, Feb-25, Volume: 159, Issue:8 Topics: Alzheimer Disease; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Spinal Dysraphism; United States	2002