homocysteine has been researched along with Carcinoma, Hepatocellular in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 1 (3.03) | 18.2507 |
| 2000's | 15 (45.45) | 29.6817 |
| 2010's | 12 (36.36) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Bertino, G; Bonfiglio, C; Catania, VE; Drago, F; Madeddu, R; Malaguarnera, G; Malaguarnera, M | 1 |
| Cen, B; Li, H; Lian, Z; Lin, Z; Lu, D; Tan, W; Wei, X; Xu, X; Yang, M; Yang, X; Zheng, S; Zhuo, J | 1 |
| Cai, H; Hu, Y; Huang, S; Liu, F; Wang, L; Wu, F; Xu, J; Yu, J; Zhou, Y | 1 |
| Bertino, G; Borzì, AM; Catania, VE; Drago, F; La Greca, G; Latteri, S; Malaguarnera, G; Malaguarnera, M | 1 |
| Pellanda, H | 1 |
| Chen, YM; Chiang, EP; Lin, WL; Lin, YJ; Tang, FY; Wang, YC | 1 |
| Banerjee, R; Chi, YY; DeRatt, BN; Gregory, JF; Kabil, O; Ralat, MA | 1 |
| Cheng, SB; Huang, YC; Lai, CY; Lin, PT; Liu, HT | 1 |
| Cheng, SB; Huang, SC; Huang, YC; Lin, PT; Liu, HT; Peng, YS | 1 |
| Cuoghi, C; Fiorini, M; Marcacci, M; Marchini, S; Pietrangelo, A; Ventura, P; Venturelli, G | 1 |
| Cui, W; Lou, J; Niu, N; Wang, F; Wang, Y; Wu, Y; Xu, D; Zhang, D; Zhang, L; Zhang, X | 1 |
| Elias, MS; Green, RM; Henkel, AS | 1 |
| Guan, DY; Shen, ZH; Wang, H; Xu, YY; Yang, M | 1 |
| Chen, SY; Chen, YM; Chiang, EP; Tang, FY; Wang, YC | 1 |
| Duan, L; Lv, J; Ma, L; Yu, X; Zhu, Y | 1 |
| Brosnan, JT; Brosnan, ME; Jacobs, RL; Kraus, JP; Maclean, KN; Ratnam, S | 1 |
| Hultberg, B | 3 |
| Banerjee, R; Oltean, S | 1 |
| Rowling, MJ; Schalinske, KL | 1 |
| Antoniou, P; Kouroumalis, EA; Koutroubakis, IE; Malliaraki, N; Romanos, J; Samonakis, DN; Sfiridaki, A | 1 |
| Barve, S; Chen, T; Kang, YJ; McClain, CJ; Song, Z; Uriarte, S; Wang, L; Zhou, Z | 1 |
| Andersson, A; Hultberg, B; Hultberg, M; Isaksson, A | 1 |
| Fotakis, G; Timbrell, JA | 1 |
| Hultberg, B; Hultberg, M | 1 |
| Chan, C; Ji, C; Kaplowitz, N; Kuhlenkamp, J; Shinohara, M | 1 |
| Andersson, A; Hultberg, B; Isaksson, A | 1 |
| Banerjee, R; Cranford, MR; Mosharov, E | 1 |
| Chen, YH; Cheng, JT; Chern, CL; Huang, RF; Liu, TZ | 1 |
| Kuchino, Y; Nishimura, S; Yasuda, T | 1 |
| Coward, J; Kaehler, M; Rottman, F | 1 |
| Kerr, SJ | 1 |
1 review(s) available for homocysteine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Betaine homocysteine methyltransferase (BHMT)-dependent remethylation pathway in human healthy and tumoral liver.
Topics: Betaine-Homocysteine S-Methyltransferase; Carbon; Carcinoma, Hepatocellular; Homocysteine; Humans; Liver Neoplasms; Methionine Adenosyltransferase | 2013 |
1 trial(s) available for homocysteine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Vitamin B-6 Supplementation Could Mediate Antioxidant Capacity by Reducing Plasma Homocysteine Concentration in Patients with Hepatocellular Carcinoma after Tumor Resection.
Topics: Adult; Aged; Antioxidants; Carcinoma, Hepatocellular; Female; Homocysteine; Humans; Liver Neoplasms; Male; Middle Aged; Vitamin B 6 | 2016 |
31 other study(ies) available for homocysteine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Serum Folate deficiency in HCV related Hepatocellular Carcinoma.
Topics: Carcinoma, Hepatocellular; Folic Acid; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Homocysteine; Humans; Liver Cirrhosis; Liver Neoplasms; RNA | 2022 |
Homocysteine: A novel prognostic biomarker in liver transplantation for alpha-fetoprotein- negative hepatocellular carcinoma.
Topics: Adult; alpha-Fetoproteins; Biomarkers, Tumor; Carcinoma, Hepatocellular; Disease-Free Survival; Female; Homocysteine; Humans; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Neoplasm Recurrence, Local; Patient Selection; Predictive Value of Tests; Preoperative Period; Prognosis; Retrospective Studies; Risk Assessment | 2020 |
A pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Cystathionine beta-Synthase; Female; HCT116 Cells; HEK293 Cells; Hep G2 Cells; Homocysteine; Humans; Hydrogen Sulfide; Liver Neoplasms; Mice; Mice, Inbred ICR; Rats | 2018 |
Homocysteine Serum Levels as Prognostic Marker of Hepatocellular Carcinoma with Portal Vein Thrombosis.
Topics: Adult; Aged; Biomarkers, Tumor; Budd-Chiari Syndrome; Carcinoma, Hepatocellular; Cholesterol, LDL; Female; Folic Acid; Homocysteine; Humans; Liver Neoplasms; Male; Middle Aged; Portal Vein; Prognosis; Vitamin B 12; Vitamin B 6 | 2019 |
A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
Topics: Adenosine; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Dietary Supplements; DNA Damage; DNA Methylation; Female; Fluorescent Antibody Technique, Indirect; Folic Acid; Glycine N-Methyltransferase; Hepatocytes; Homocysteine; Humans; Liver; Liver Neoplasms; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Knockout; Minor Histocompatibility Antigens; Protein Transport; Purines; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uracil | 2014 |
Vitamin B-6 restriction reduces the production of hydrogen sulfide and its biomarkers by the transsulfuration pathway in cultured human hepatoma cells.
Topics: Alanine; Biomarkers; Carcinoma, Hepatocellular; Cysteine; Hep G2 Cells; Homocysteine; Humans; Hydrogen Sulfide; Linear Models; Liver Neoplasms; Pyridoxal Phosphate; Sulfides; Vitamin B 6; Vitamin B 6 Deficiency | 2014 |
Folate and vitamin B-6 status are not associated with homocysteine, oxidative stress and antioxidant capacities in patients with hepatocellular carcinoma.
Topics: Aged; Antioxidants; Carcinoma, Hepatocellular; Female; Folic Acid; Glutathione Peroxidase; Glutathione Transferase; Homocysteine; Humans; Liver Neoplasms; Male; Malondialdehyde; Middle Aged; Nutritional Status; Oxidative Stress; Pyridoxal Phosphate; Superoxide Dismutase; Vitamin B 6 | 2016 |
Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis.
Topics: Aged; Carcinoma, Hepatocellular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis; Liver Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Portal Vein; Retrospective Studies; Venous Thrombosis | 2016 |
Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation.
Topics: Adult; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; DNA Methylation; Eicosanoids; Female; Hep G2 Cells; Homocysteine; Humans; Hyperhomocysteinemia; Immunohistochemistry; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transplantation, Heterologous | 2017 |
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Fatty Liver; Female; Homocysteine; Liver; Liver Neoplasms; Methionine; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Unfolded Protein Response | 2009 |
All-trans-retinoic acid intensifies endoplasmic reticulum stress in N-acetylglucosaminyltransferase V repressed human hepatocarcinoma cells by perturbing homocysteine metabolism.
Topics: Antineoplastic Agents; Apoptosis; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Line, Tumor; Cystathionine beta-Synthase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Homocysteine; Humans; Liver Neoplasms; N-Acetylglucosaminyltransferases; Tretinoin | 2010 |
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
Homocysteine inhibits hepatocyte proliferation via endoplasmic reticulum stress.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatocytes; Homocysteine; Humans; Lithium Chloride; Mice; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tumor Suppressor Protein p53 | 2013 |
Hormonal regulation of cystathionine beta-synthase expression in liver.
Topics: Animals; Blood Glucose; Carcinoma, Hepatocellular; Cystathionine beta-Synthase; Diabetes Mellitus, Experimental; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Kinetics; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Triamcinolone; Tumor Cells, Cultured | 2002 |
Modulation of extracellular homocysteine concentration in human cell lines.
Topics: Acetylcysteine; Amino Acid Transport Systems; Carcinoma, Hepatocellular; Copper; Cysteine; Dithiothreitol; Extracellular Fluid; HeLa Cells; Homocysteine; Humans; Oxidation-Reduction; Sulfhydryl Compounds; Sulfonic Acids; Tumor Cells, Cultured | 2003 |
Nutritional modulation of gene expression and homocysteine utilization by vitamin B12.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5' Untranslated Regions; Animals; Carcinoma, Hepatocellular; COS Cells; Gene Expression; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Kidney; Liver Neoplasms; Methylation; Nucleic Acid Conformation; Nutritional Physiological Phenomena; Polyribosomes; Protein Biosynthesis; RNA, Messenger; Tumor Cells, Cultured; Vitamin B 12 | 2003 |
Retinoic acid and glucocorticoid treatment induce hepatic glycine N-methyltransferase and lower plasma homocysteine concentrations in rats and rat hepatoma cells.
Topics: Adrenalectomy; Animals; Bucladesine; Carcinoma, Hepatocellular; Dexamethasone; Enzyme Induction; Glucocorticoids; Glycine N-Methyltransferase; Homocysteine; Liver; Liver Neoplasms; Male; Methyltransferases; Rats; Rats, Sprague-Dawley; Tretinoin; Tumor Cells, Cultured | 2003 |
Extracellular concentration of homocysteine in human cell lines is influenced by specific inhibitors of cyst(e)ine transport.
Topics: Amino Acid Transport Systems; Biological Transport; Carcinoma, Hepatocellular; Cysteine; Extracellular Fluid; HeLa Cells; Homocysteine; Humans; Liver Neoplasms; Tumor Cells, Cultured | 2004 |
Hypercoagulable states in patients with hepatocellular carcinoma.
Topics: Adult; Aged; Antithrombins; Carcinoma, Hepatocellular; Female; Homocysteine; Humans; Lipoprotein(a); Liver Neoplasms; Male; Middle Aged; Protein C; Protein S; Thrombophilia | 2004 |
S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease.
Topics: Adenosine; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Caspase 8; Caspases; Cell Line, Tumor; Hepatocytes; Homocysteine; Humans; Liver Diseases, Alcoholic; Methylation; Mice; Mice, Inbred C57BL; NF-kappa B; S-Adenosylhomocysteine; Tumor Necrosis Factor-alpha | 2004 |
Elimination of high amounts of extracellular homocysteine in human cell lines.
Topics: Adenosine; Antioxidants; Arteriosclerosis; Carcinoma, Hepatocellular; Cell Line, Tumor; HeLa Cells; Homocysteine; Humans; Hyperhomocysteinemia; Thioctic Acid | 2005 |
The polyphenol quercetin strongly increases homocysteine production in a human hepatoma (Hep G2) cell line.
Topics: Adenosine; Adenosylhomocysteinase; Antioxidants; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme Inhibitors; HeLa Cells; Homocysteine; Humans; Quercetin | 2006 |
Modulation of cadmium chloride toxicity by sulphur amino acids in hepatoma cells.
Topics: Cadmium Chloride; Carcinoma, Hepatocellular; Cystathionine; Cysteine; Cytoprotection; Glutathione; Homocysteine; Humans; Tumor Cells, Cultured | 2006 |
Oxidative stress decreases extracellular homocysteine concentration in human hepatoma (HepG2) cell cultures.
Topics: Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Line, Tumor; Extracellular Fluid; HeLa Cells; Homocysteine; Humans; Hydrogen Peroxide; Oxidative Stress; Sulfur; Time Factors | 2007 |
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.
Topics: Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Fatty Liver; Gene Transfer Techniques; Hepatocytes; Homocysteine; Humans; Lipid Metabolism; Liver Neoplasms; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Sterol Regulatory Element Binding Protein 1 | 2007 |
Alterations of thiol metabolism in human cell lines induced by low amounts of copper, mercury or cadmium ions.
Topics: Cadmium; Carcinoma, Hepatocellular; Cell Line; Copper; Culture Media; Cysteine; Dipeptides; Endothelium; gamma-Glutamyltransferase; Glutathione; HeLa Cells; Homocysteine; Humans; Mercury; Tumor Cells, Cultured | 1998 |
The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cystathionine; Cystathionine beta-Synthase; Glutathione; Hepatocytes; Homocysteine; Humans; Intracellular Fluid; Oxidation-Reduction; Oxidative Stress; Sulfur; tert-Butylhydroperoxide; Tumor Cells, Cultured | 2000 |
Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Catalase; Cell Division; DNA Fragmentation; DNA, Neoplasm; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Homocysteine; Humans; Hydrogen Peroxide; Malondialdehyde; Methionine; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Transcription Factors; Tumor Cells, Cultured | 2001 |
Deficiency of S-adenosylmethionine-homocysteine methyltransferase activity in hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Female; Homocysteine; Hydrolases; Liver; Liver Neoplasms; Methyltransferases; Neoplasms, Experimental; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1977 |
In vivo inhibition of Novikoff cytoplasmic messenger RNA methylation by S-tubercidinylhomocysteine.
Topics: Carcinoma, Hepatocellular; Cell Line; Homocysteine; Liver Neoplasms; Neoplasms, Experimental; Oligoribonucleotides; Poly A; RNA, Messenger; S-Adenosylhomocysteine | 1977 |
Competing methyltransferase systems.
Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Glycine; Homocysteine; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Mice; Molecular Weight; Pancreas; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine | 1972 |