homocysteine and Bone Fractures

homocysteine has been researched along with Bone Fractures in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's22 (61.11)29.6817
2010's9 (25.00)24.3611
2020's5 (13.89)2.80

Authors

AuthorsStudies
Faliva, MA; Fossari, F; Naso, M; Nichetti, M; Perna, S; Peroni, G; Rondanelli, M; Tartara, A; Vecchio, V1
Ilesanmi-Oyelere, BL; Kruger, MC1
Fu, L; Hu, YQ; Wang, Y1
de Groot, LCPGM; Kiefte-de Jong, JC; Lips, P; Oliai Araghi, S; Ploegmakers, KJ; Stricker, BH; Swart, KMA; Uitterlinden, AG; van der Velde, N; van Dijk, SC; van Schoor, NM; Zillikens, MC1
Lei, SF; Liu, L; Wang, P1
Lips, P; Swart, KM; van Schoor, NM1
Åkesson, K; Garg, G; Gerdhem, P; Kumar, J; Luthman, H; McGuigan, FE; Ridderstråle, M1
Clarke, M; Dickey, W; Hoey, L; McNulty, H; Strain, JJ; Ward, M1
Kanazawa, I; Sugimoto, T1
Selhub, J2
Inoue, S; Kuroda, T; Miyao-Koshizuka, M; Saito, M; Shiraki, M; Tanaka, S; Urano, T1
Donaldson, MG; Liu-Ambrose, T1
Beilby, J; Devine, A; Dick, IM; Prince, RL; Soós, M; Zhu, K1
Saito, M1
Chun, S; Chung, SJ; Kim, BJ; Kim, GS; Kim, HK; Kim, MJ; Kim, SR; Koh, JM; Lee, MC; Lee, SH; Ryu, JS1
Higuchi, T; Kuroda, T; Saito, M; Shiraki, M; Shiraki, Y; Tanaka, S1
Marumo, K; Saito, M1
de Jonge, R; de Muinck Keizer-Schrama, SM; Hop, WC; Pieters, R; te Winkel, ML; van Beek, RD; van den Heuvel-Eibrink, MM; van der Sluis, IM1
Cao, H; Hu, X; Liu, B; Wang, J; Yang, J; Zhang, Q1
Bathum, L; Christensen, K; Christiansen, L; Madsen, JS; Skytthe, A; von Bornemann Hjelmborg, J1
Breteler, MM; de Groot, LC; de Jonge, R; Dhonukshe-Rutten, RA; Hofman, A; Lindemans, J; Lips, P; Pluijm, SM; Pols, HA; Uitterlinden, AG; van der Klift, M; van Leeuwen, JP; van Meurs, JB; Witteman, JC1
Raisz, LG1
Blackburn, GL1
Cashman, KD1
de Groot, LC; Dhonukshe-Rutten, RA; Lips, P; Pluijm, SM; Smit, JH; van Staveren, WA1
Bauer, DC; Jamal, SA; Leiter, RE1
Bastagli, L; Brunetti, N; Cucinotta, D; Forti, P; Maioli, F; Mariani, E; Martelli, M; Ravaglia, G; Servadei, L1
Belmaker, RH; Levine, J1
Kim, DJ; Kim, GS; Kim, HH; Kim, YS; Koh, JM; Lee, KU; Lee, YS; Park, JY1
Akesson, K; Gerdhem, P; Isaksson, A; Ivaska, KK; Obrant, KJ; Pettersson, K; Väänänen, HK1
de Jonge, R; Hofman, A; Jhamai, M; Lindemans, J; Pols, HA; Rivadeneira, F; Uitterlinden, AG; van Meurs, JB; Yazdanpanah, N; Zillikens, MC1
Hannan, MT; McLean, RR1
Josse, RG; Lonn, E; Ray, JG; Sawka, AM; Yi, Q1
Takeuchi, Y1
Dyer, AR; Eksarko, P; Lee, C; Pope, RM; Ramsey-Goldman, R; Rhew, EY; Spies, S; Tily, H1

Reviews

14 review(s) available for homocysteine and Bone Fractures

ArticleYear
Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Current aging science, 2022, Volume: 15, Issue:2

    Topics: Aged; Bone Density; Dietary Supplements; Eating; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex

2022
B vitamins and homocysteine as determinants of bone health: A literature review of human studies.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2023, Volume: 36, Issue:3

    Topics: Bone and Bones; Bone Density; Folic Acid; Fractures, Bone; Homocysteine; Humans; Osteoporosis; Vitamin B 12; Vitamin B Complex

2023
Causal effects of homocysteine levels on the changes of bone mineral density and risk for bone fracture: A two-sample mendelian randomization study.
    Clinical nutrition (Edinburgh, Scotland), 2021, Volume: 40, Issue:4

    Topics: Bone Density; Causality; Female; Femur Neck; Forearm; Fractures, Bone; Genome-Wide Association Study; Homocysteine; Humans; Lumbar Vertebrae; Male; Mendelian Randomization Analysis; Middle Aged; Risk Assessment; Risk Factors

2021
Vitamin B12, folic acid, and bone.
    Current osteoporosis reports, 2013, Volume: 11, Issue:3

    Topics: Bone and Bones; Bone Density; Dietary Supplements; Folic Acid; Fractures, Bone; Homocysteine; Humans; Prevalence; Vitamin B 12

2013
B-vitamins and bone in health and disease: the current evidence.
    The Proceedings of the Nutrition Society, 2014, Volume: 73, Issue:2

    Topics: Bone and Bones; Bone Density; Celiac Disease; Folic Acid; Fractures, Bone; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Osteoporosis; Polymorphism, Single Nucleotide; Vitamin B Complex; Vitamin B Deficiency

2014
Public health significance of elevated homocysteine.
    Food and nutrition bulletin, 2008, Volume: 29, Issue:2 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neural Tube Defects; Pregnancy; Public Health; Risk Factors; Vitamin B 12; Vitamin B 6

2008
Exercise and cognition in older adults: is there a role for resistance training programmes?
    British journal of sports medicine, 2009, Volume: 43, Issue:1

    Topics: Accidental Falls; Aged; Cognition; Cognition Disorders; Fractures, Bone; Homocysteine; Humans; Insulin-Like Growth Factor I; Resistance Training

2009
[Poor bone quality in diabetes and arterioscelerosis].
    Clinical calcium, 2009, Volume: 19, Issue:9

    Topics: Animals; Arginine; Arteriosclerosis; Biomarkers; Bone Density; Collagen; Diabetes Complications; Diabetes Mellitus; Fractures, Bone; Glycation End Products, Advanced; Homocysteine; Humans; Lysine; Osteoporosis; Risk

2009
[CKD-MBD (Chronic Kidney Disease-Mineral and Bone Disorder). Bone quality in chronic kidney disease : enzymatic and non-enzymatic glycation or oxidation induced cross-links in bone].
    Clinical calcium, 2010, Volume: 20, Issue:7

    Topics: Animals; Arginine; Bone and Bones; Bone Diseases, Metabolic; Chronic Disease; Collagen; Fractures, Bone; Glycation End Products, Advanced; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Lysine; Osteoporosis; Oxidative Stress; Risk

2010
Homocysteine level and risk of fracture: A meta-analysis and systematic review.
    Bone, 2012, Volume: 51, Issue:3

    Topics: Clinical Trials as Topic; Fractures, Bone; Homocysteine; Humans; Publication Bias; Quality Assurance, Health Care; Risk Factors

2012
Homocysteine and osteoporotic fracture risk: a potential role for B vitamins.
    Nutrition reviews, 2005, Volume: 63, Issue:1

    Topics: Bone and Bones; Fractures, Bone; Genotype; Homocysteine; Humans; Osteoporosis; Risk Factors; Vitamin B Complex

2005
The many facets of hyperhomocysteinemia: studies from the Framingham cohorts.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Massachusetts; Middle Aged; Risk Factors; Stroke; Vascular Diseases; Vitamin B 12; Vitamin B 6

2006
B vitamins, homocysteine, and bone disease: epidemiology and pathophysiology.
    Current osteoporosis reports, 2007, Volume: 5, Issue:3

    Topics: Bone Density; Fractures, Bone; Homocysteine; Humans; Osteoporosis; Risk Factors; Vitamin B Complex

2007
[Assessment of bone quality with metabolic bone markers].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Nov-28, Volume: 65 Suppl 9

    Topics: Alkaline Phosphatase; Amino Acids; Arginine; Biomarkers; Bone and Bones; Bone Resorption; Collagen Type I; Forecasting; Fractures, Bone; Homocysteine; Humans; Lysine; Osteocalcin; Osteogenesis; Peptides; Tensile Strength

2007

Trials

2 trial(s) available for homocysteine and Bone Fractures

ArticleYear
Long-term effects of folic acid and vitamin-B12 supplementation on fracture risk and cardiovascular disease: Extended follow-up of the B-PROOF trial.
    Clinical nutrition (Edinburgh, Scotland), 2021, Volume: 40, Issue:3

    Topics: Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Fractures, Bone; Homocysteine; Humans; Male; Odds Ratio; Osteoporotic Fractures; Placebos; Risk Factors; Vitamin B 12

2021
Randomized clinical trial of homocysteine level lowering therapy and fractures.
    Archives of internal medicine, 2007, Oct-22, Volume: 167, Issue:19

    Topics: Aged; Cardiovascular Diseases; Drug Therapy, Combination; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Proportional Hazards Models; Pyridoxine; Risk Factors; Treatment Outcome; Vitamin B 12

2007

Other Studies

20 other study(ies) available for homocysteine and Bone Fractures

ArticleYear
Inferring causal effects of homocysteine and B-vitamin concentrations on bone mineral density and fractures: Mendelian randomization analyses.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Bone Density; Female; Fractures, Bone; Genome-Wide Association Study; Homocysteine; Humans; Male; Mendelian Randomization Analysis; Middle Aged; Vitamin B 12; Vitamin B Complex

2022
Variation in the MC4R gene is associated with bone phenotypes in elderly Swedish women.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adiposity; Aged; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Biomarkers; Body Composition; Bone and Bones; Cohort Studies; Female; Fractures, Bone; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Obesity; Phenotype; Polymorphism, Single Nucleotide; Proteins; Receptor, Melanocortin, Type 4; Sweden; Ultrasonography

2014
[Diabetes mellitus and bone].
    Clinical calcium, 2016, Volume: 26, Issue:8

    Topics: Animals; Bone and Bones; Bone Density; Diabetes Complications; Diabetes Mellitus; Fractures, Bone; Glycation End Products, Advanced; Homocysteine; Humans

2016
The synergistic effect of bone mineral density and methylenetetrahydrofolate reductase (MTHFR) polymorphism (C677T) on fractures.
    Journal of bone and mineral metabolism, 2008, Volume: 26, Issue:6

    Topics: Aged; Bone Density; Bone Resorption; Female; Fractures, Bone; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors

2008
The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly women.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009, Volume: 20, Issue:7

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Bone Density; Female; Fractures, Bone; Hip Joint; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Osteoporosis, Postmenopausal; Polymorphism, Single Nucleotide; Prospective Studies; Western Australia

2009
Hyperhomocysteinemia due to levodopa treatment as a risk factor for osteoporosis in patients with Parkinson's disease.
    Calcified tissue international, 2010, Volume: 86, Issue:2

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Bone and Bones; Bone Density; Causality; Cohort Studies; Comorbidity; Female; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Osteoporosis; Prevalence; Risk Factors; Up-Regulation

2010
Urinary pentosidine and plasma homocysteine levels at baseline predict future fractures in osteoporosis patients under bisphosphonate treatment.
    Journal of bone and mineral metabolism, 2011, Volume: 29, Issue:1

    Topics: Aged; Arginine; Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Fractures, Bone; Homocysteine; Humans; Lysine; Middle Aged; Osteoporosis; Proportional Hazards Models

2011
Germline variation in the MTHFR and MTRR genes determines the nadir of bone density in pediatric acute lymphoblastic leukemia: a prospective study.
    Bone, 2011, Mar-01, Volume: 48, Issue:3

    Topics: Absorptiometry, Photon; Adolescent; Biomarkers, Tumor; Bone Density; Case-Control Studies; Child; Child, Preschool; Ferredoxin-NADP Reductase; Folic Acid; Fractures, Bone; Genotype; Germ Cells; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Vitamin B 12

2011
Evidence for an association of methylene tetrahydrofolate reductase polymorphism C677T and an increased risk of fractures: results from a population-based Danish twin study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2004, Volume: 15, Issue:8

    Topics: Aged; Denmark; Female; Fractures, Bone; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Osteoporosis; Polymorphism, Genetic; Population Surveillance; Risk Factors; Twins

2004
Homocysteine levels and the risk of osteoporotic fracture.
    The New England journal of medicine, 2004, May-13, Volume: 350, Issue:20

    Topics: Aged; Bone Density; Cohort Studies; Female; Follow-Up Studies; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osteoporosis; Proportional Hazards Models; Risk; Risk Factors

2004
Homocysteine and osteoporotic fractures--culprit or bystander?
    The New England journal of medicine, 2004, May-13, Volume: 350, Issue:20

    Topics: Estradiol; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors

2004
A new risk factor for fractures? Diets low in B vitamins may leave people more prone to broken bones.
    Health news (Waltham, Mass.), 2004, Volume: 10, Issue:7

    Topics: Female; Fractures, Bone; Homocysteine; Humans; Male; Middle Aged; Osteoporosis; Risk Factors; Vitamin B Complex

2004
Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:6

    Topics: Aged; Aged, 80 and over; Body Weight; Bone and Bones; Cohort Studies; Creatine; Female; Fractures, Bone; Homocysteine; Humans; Immunoassay; Immunoradiometric Assay; Male; Middle Aged; Osteocalcin; Osteoporosis; Proportional Hazards Models; Regression Analysis; Risk; Risk Factors; Time Factors; Ultrasonography; Vitamin B 12

2005
Hyperhomocysteinaemia and aortic calcification are associated with fractures in patients on haemodialysis.
    QJM : monthly journal of the Association of Physicians, 2005, Volume: 98, Issue:8

    Topics: Aged; Calcinosis; Cross-Sectional Studies; Female; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Spinal Fractures; Vascular Diseases

2005
Folate, but not homocysteine, predicts the risk of fracture in elderly persons.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2005, Volume: 60, Issue:11

    Topics: Aged; Aged, 80 and over; Bone Diseases, Metabolic; Chromatography, High Pressure Liquid; Confounding Factors, Epidemiologic; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Italy; Male; Multivariate Analysis; Risk Factors

2005
Osteoporosis and schizophrenia.
    The American journal of psychiatry, 2006, Volume: 163, Issue:3

    Topics: Bone Density; Comorbidity; Female; Fractures, Bone; Homocysteine; Humans; Male; Osteoporosis; Schizophrenia; Sex Factors

2006
Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2006, Volume: 21, Issue:7

    Topics: Acid Phosphatase; Animals; Bone Marrow Cells; Bone Resorption; Cell Differentiation; Cells, Cultured; Fractures, Bone; Homocysteine; Hyperhomocysteinemia; Isoenzymes; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Osteoclasts; Osteoporosis; Protein Kinases; Reactive Oxygen Species; Risk Factors; Tartrate-Resistant Acid Phosphatase

2006
Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:1

    Topics: Aged; Biomarkers; Bone and Bones; Bone Density; Female; Follow-Up Studies; Fractures, Bone; Homocysteine; Humans; Risk Factors; Surveys and Questionnaires; Survival Analysis

2007
Low dietary riboflavin but not folate predicts increased fracture risk in postmenopausal women homozygous for the MTHFR 677 T allele.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2008, Volume: 23, Issue:1

    Topics: Aged; Alleles; Bone Density; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Fractures, Bone; Genotype; Homocysteine; Humans; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osteoporosis, Postmenopausal; Postmenopause; Riboflavin; Riboflavin Deficiency; Risk Factors

2008
Homocysteine, bone mineral density, and fracture risk over 2 years of followup in women with and without systemic lupus erythematosus.
    The Journal of rheumatology, 2008, Volume: 35, Issue:2

    Topics: Adult; Bone Density; Case-Control Studies; Female; Follow-Up Studies; Fractures, Bone; Homocysteine; Humans; Lupus Erythematosus, Systemic; Middle Aged; Odds Ratio; Risk Factors

2008
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