homocysteine has been researched along with Alzheimer Disease in 346 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (1.16) | 18.2507 |
2000's | 170 (49.13) | 29.6817 |
2010's | 140 (40.46) | 24.3611 |
2020's | 32 (9.25) | 2.80 |
Authors | Studies |
---|---|
de Paula, AMB; Engedal, K; Felício, LFF; Kristiansen, KM; Leão, LL; Monteiro-Junior, RS; Santos, SHS; Tangen, GG | 1 |
Baldinelli, S; Fiori, C; Luzzi, S; Papiri, G; Silvestrini, M; Toraldo, A; Viticchi, G | 1 |
Gupta, JK; Srivastava, R; Varshney, KK; Verma, N | 1 |
Abd El Moneim, RA; El-Mezayen, NS; El-Rewini, SH | 1 |
Liu, C; Luo, G; Wang, X | 1 |
Cicognola, C; Frölich, K; Londos, E; Nyholm, E; Torkpoor, R | 1 |
Liu, Q; Liu, X; Meng, Y; Shi, L; Zhang, L; Zhang, W; Zhang, X | 1 |
Jia, J; Li, T; Quan, M; Song, Y | 1 |
Guo, R; He, J; Quan, L; Zhou, K | 1 |
Alexander, GE; Bharadwaj, PK; Habeck, CG; Hishaw, GA; Huentelman, MJ; Raichlen, DA; Song, H; Trouard, TP | 1 |
Futschek, IE; Haslacher, H; Lehrner, J; Schernhammer, E; Stögmann, E | 1 |
Dionne, IJ; Maltais, M; Rolland, Y; St-Martin, P | 1 |
Darabi, M; Hoseinlar, SF; Laghousi, D; Nikanfar, M; Nourazarian, A; Shademan, B | 1 |
Bian, J; Jiao, X; Li, Y; Liu, G; Song, Y; Tang, B; Wang, X; Xie, X; Zhang, J; Zhao, Y | 1 |
Bottiglieri, T; Fardo, DW; Johnson, SN; Qiao, Q; Rogers, CB; Sudduth, TL; Weekman, EM; Wilcock, DM; Xie, K | 1 |
Chung, HW; Hsu, YH; Tu, MC; Wu, WC; Yang, JJ | 1 |
An, P; Chen, H; Du, Y; Gao, Y; Huang, G; Ji, Y; Liu, S; Lv, X; Ma, F; Song, A; Sun, C; Wang, G; Wang, X; Xu, W; Zhao, J; Zhou, X | 1 |
Berge, G; Bråthen, G; Edlund, AK; Giannisis, A; Grøntvedt, GR; Lauridsen, C; Nielsen, HM; Patra, K; Sando, SB; White, LR | 1 |
An, Y; Feng, L; Qin, Z; Tao, L; Wang, Y; Xiao, R; Zhang, X | 1 |
Abohamza, E; Berry, T; Moustafa, AA | 1 |
Guo, J; Li, Y; Meng, H; Niu, X; Zhang, W; Zhao, Y | 1 |
An, DD; Liu, R; Lu, YM; Ohlmeyer, M; Shu, XJ; Wan, L; Wang, JZ; Wang, XC; Wei, H; Westermarck, J; Xie, JZ; Zeng, Y; Zhang, HL | 1 |
Al-Shabrawey, M; Alhusban, S; Elsherbiny, NM; Jadeja, R; Kira, D; Martin, P; Samra, YA; Sharma, I; Tawfik, A | 1 |
Chen, S; Furuta, Y; Hata, J; Hirakawa, Y; Honda, T; Kitazono, T; Ninomiya, T; Ohara, T; Oishi, E; Sakata, S; Shibata, M; Yoshida, D | 1 |
Al-Shabrawey, M; Elsherbiny, NM; Samra, YA; Tawfik, A | 1 |
Nazıroğlu, M; Övey, İS | 1 |
Liu, B; Pi, T; Shi, J | 1 |
Bouyahia, A; de Souto Barreto, P; Fischer, C; Giudici, KV; Lu, WH; Mangin, JF; Rolland, Y; Vellas, B | 1 |
Arocha-Oriol, C; Calvo-Rodríguez, M; Díaz-Domínguez, M; Eugenia, M; García-Klibanski, M; Guerra-Hernández, M; Herrera-Javier, D; Jesús, J; Lanyau-Domínguez, Y; Macías-Matos, C; María, G; Noriega-Fernández, L; Sánchez-Gil, Y; Suárez-Medina, R | 1 |
Gabelli, C; Reffo, A | 1 |
Chen, H; Chen, J; Fu, G; Han, H; Li, X; Wang, F; Wu, W; Zhou, D; Zhou, J | 1 |
Cascavilla, L; Ciccone, F; D'Onofrio, G; Germano, C; Greco, A; Lauriola, M; Paris, F | 1 |
Adsi, H; Bera, S; Do, TD; Frenkel, D; Gartner, M; Gazit, E; Kreiser, T; Laor Bar-Yosef, D; Levy, D; Oluwatoba, DS; Sade Yazdi, D; Shaham-Niv, S; Sigal, S; Zaguri, D | 1 |
Bae, JB; Han, JW; Jhoo, JH; Kim, BJ; Kim, JL; Kim, KW; Kim, SG; Kim, TH; Kwak, KP; Lee, DW; Lee, DY; Lee, JJ; Lee, K; Lee, SB; Moon, SW; Park, JH; Ryu, SH; Song, J; Youn, JC | 1 |
Gan, Y; Jiang, H; Li, H; Liu, M; Yao, S; Yin, G; Yin, P; Yu, T; Zhang, Y | 1 |
Barrero, C; Li, JG; Merali, S; Praticò, D | 1 |
He, J; Huang, M; Lin, Y; Pu, Z; Xu, W | 1 |
Bowman, GL; Collino, S; Corthésy, J; Da Silva, L; Dayon, L; Descombes, P; Guiraud, SP; Henry, H; Kussmann, M; Marquis, J; Martin, FJ; Métairon, S; Migliavacca, E; Montoliu, I; Moullet, B; Oikonomidi, A; Popp, J; Tautvydaitė, D; Wojcik, J | 1 |
Alexopoulos, P; Arbones, M; Badel, A; Camproux, AC; Delabar, JM; Dubois, B; Feraudet-Tarisse, C; Janel, N; Lagarde, J; Lamari, F; Lamourette, P; Paul, JL; Potier, MC; Sarazin, M; Simon, S | 1 |
Ding, S; Sun, J; Wen, S; Zhou, J | 1 |
Huang, G; Ji, L; Ma, F; Song, A; Wu, T; Zhang, M; Zhao, J | 1 |
Filhine-Trésarrieu, P; Guéant, JL; Levy, J; Namour, F; Oussalah, A | 1 |
Chang, CC; Chang, WN; Chen, PC; Chen, SF; Hsu, SW; Huang, CW; Hwang, LC; Lee, CC; Wu, MK | 1 |
Farina, N; Hart, K; Jernerén, F; Tabet, N; Turner, C | 1 |
Bennett, DA; De Jager, PL; Felsky, D; Nazeri, A; Roostaei, T; Schneider, JA; Voineskos, AN | 1 |
Andrieu, S; Bowman, GL; Caussé, E; Cesari, M; Coley, N; De Souto Barreto, P; Hooper, C; Payoux, P; Salabert, AS; Vellas, B; Weiner, M | 1 |
Di Meco, A; Li, JG; Praticò, D | 1 |
Bosi, C; Brombo, G; Cervellati, C; Morieri, ML; Passaro, A; Trentini, A; Valacchi, G; Zuliani, G; Zurlo, A | 1 |
Kim, H; Kim, J; Kwon, Y; Roh, H | 1 |
Hamano, T; Hayashi, K; Ikawa, M; Kanaan, NM; Kuriyama, M; Nakamoto, Y; Shirafuji, N; Yamamura, O; Yen, SH; Yoshida, H | 1 |
Bao, J; Chen, D; Huang, F; Ke, D; Liu, R; Mahaman, YAR; Salissou, MTM; Wang, JZ; Wang, Q; Wang, X; Wang, Y; Wei, Z; Wu, M; Zhang, B | 1 |
Barrero, C; Di Meco, A; Li, JG; Merali, S; Praticò, D | 1 |
Benakova, H; Fisar, Z; Hroudova, J; Jirak, R; Kitzlerova, E; Lelkova, P; Martasek, P; Raboch, J; Zverova, M | 1 |
Arning, E; Bottiglieri, T; Hoffman, A; Qian, H; Sontag, E; Sontag, JM; Taleski, G; Wasek, B | 1 |
Adamkov, M; Kalenska, D; Kovalska, L; Kovalska, M; Lehotsky, J; Tatarkova, Z; Tomascova, A; Tothova, B | 1 |
Bhadelia, RA; Folstein, MF; Qiu, WQ; Rosenberg, IH; Scott, TM | 1 |
Guo, J; Li, Q; Ni, S; Wang, JZ; Yang, Y | 1 |
Cortina-Borja, M; Lehmann, DJ | 1 |
Huang, F; Ke, D; Liu, R; Mahaman, YAR; Salissou, MTM; Wang, JZ; Wang, Q; Wang, X; Wang, Y; Xu, Z; Zhang, B; Zhu, F | 1 |
Andrews, RD; de Leon, MJ; Ganzer, C; Isaacson, RS; Matthews, DC; Mosconi, L; Osorio, RS; Quinn, C; Sterling, J; Vallabhajosula, S; Walters, MJ | 1 |
Caccamo, A; Dave, N; Ferreira, E; Huentelman, MJ; Naymik, M; Oddo, S; Piras, IS; Tran, A; Velazquez, R; Winslow, W | 1 |
Chen, S; Zhou, F | 1 |
Basun, H; Cederholm, T; Eriksdotter, M; Faxen-Irving, G; Freund-Levi, Y; Hjorth, E; Jernerén, F; Palmblad, J; Refsum, H; Schultzberg, M; Smith, AD; Turner, C; Wahlund, LO | 1 |
Ferreirós, N; Fleck, SC; Geisslinger, G; Gurke, R; Schmidt, D; Thomas, D | 1 |
Barber, RC; Edwards, M; Hall, JR; Johnson, LA; O'Bryant, SE; Singh, M; Wiechmann, AR; Winter, AS | 1 |
Cheek, L; Jones, E; Smith, E; Tabet, N; Veryard, L; Weaving, G; Wickramasinghe, A | 1 |
Chang, AY; Chang, CC; Chang, WN; Chang, YT; Chen, NC; Huang, CW; Huang, SH; Lee, CC; Lui, CC | 1 |
Fischer, P; Hinterberger, M; Huber, K; Jungwirth, S; Krampla, W; Krugluger, W; Leitha, T; Tragl, KH; Zehetmayer, S | 1 |
Fekih-Mrissa, N; Gritli, N; Klai, S; Mansour, M; Mansouri, L; Mrissa, R | 1 |
de Jager, CA; Douaud, G; Jacoby, R; Nichols, TE; Refsum, H; Smith, AD; Smith, SM | 1 |
Cheng, DM; Huang, CY; Jiang, YG; Kong, HY; Liu, J; Pang, W; Sun, SD | 1 |
Cheng, YY; Hong, Y; Hou, Y; Li, YL; Niu, C; Yu, LX | 1 |
Chen, J; He, ZF; Lu, YQ; Luo, Y; Wang, Y; Yan, BL; Yu, Q | 1 |
Goutzourelas, N; Gubandru, M; Ilie, M; Kouretas, D; Margina, D; Tsarouhas, K; Tsatsakis, AM; Tsitsimpikou, C | 1 |
Erkinjuntti, T; Hooshmand, B; Kivipelto, M; Mäkelä, M; Myllykangas, L; Oinas, M; Paetau, A; Polvikoski, T; Scheltens, P; Solomon, A; Sulkava, R; Tanskanen, M; van Straaten, EC | 1 |
Bendini, M; Boldrini, P; Di Paola, F; Gallucci, M; Grossi, E; Zanardo, A | 1 |
Arab, A; Bogari, N; Elhawary, NA; Hewedi, D; Shaibah, H; Tayeb, MT; Teama, S | 1 |
Bergamini, CM; Bosi, C; Cervellati, C; Cremonini, E; Magon, S; Passaro, A; Pilotto, A; Romani, A; Seripa, D; Zuliani, G | 1 |
Gröber, U; Kisters, K; Schmidt, J | 1 |
Gard, PR; Nilforooshan, R; Richardson, C; Tabet, N; Weaving, G | 1 |
Byun, MS; Choe, YM; Choi, HJ; Han, JY; Kim, YK; Lee, DY; Lee, JM; Park, J; Seo, EH; Sohn, BK; Woo, JI; Yoon, EJ | 1 |
Barber, RC; Cunningham, R; Edwards, M; Hall, JR; Johnson, LA; O'Bryant, SE; Singh, M; Wiechmann, AR | 1 |
Benaková, H; Fisar, Z; Hroudová, J; Jirák, R; Kitzlerová, E; Raboch, J; Zvĕrová, M | 1 |
Barrero, C; Chu, J; Li, JG; Merali, S; Praticò, D | 1 |
Belarbi, S; Bendini, M; Chelouti, H; Djerdjouri, B; El Hadi Cherifi, M; Kacimi, G; Khelil, M; Nazef, K; Tazir, M | 1 |
Beydoun, HA; Beydoun, MA; Gamaldo, AA; Teel, A; Wang, Y; Zonderman, AB | 1 |
Chen, H; Cui, W; Kong, L; Wang, C; Wang, J; Yi, L; Yu, H; Zheng, Z | 1 |
Li, JG; Praticò, D | 1 |
Baierle, M; Bordignon, S; Breusing, N; Duarte, MM; Emanuelli, T; Garcia, SC; Grune, T; Oldenburg, L; Somacal, S; Trentini, CM; Veit, JC; Vencato, PH; Zibetti, M | 1 |
Devčić, S; Glamuzina, L; Mihanovic, M; Ruljancic, N | 1 |
Rabinovitz, S; Yehuda, S | 1 |
Bian, J; Chen, C; Cheng, Y; Gao, S; Hake, AM; Hendrie, HC; Jin, Y; Kettler, C; Li, P; Liu, J; Ma, F; Murrell, JR; Su, L; Unverzagt, FW; Yang, L | 1 |
Joshi, SH; Madsen, SK; Rajagopalan, P; Thompson, PM; Toga, AW | 1 |
Chang, N; Jang, W; Kim, G; Kim, H; Kim, SY | 1 |
Chen, H; Huang, G; Ji, L; Ji, Y; Liu, S; Ma, F; Wu, T; Zhang, M; Zheng, M; Zhou, Y | 1 |
Coşar, A; Gültepe, M; Ipçioğlu, OM; Ozcan, O | 1 |
Cavallaro, RA; Desiderio, C; Di Napoli, A; Fuso, A; Gervasoni, J; Giardina, B; Nicolia, V; Persichilli, S; Scarpa, S | 1 |
Ji, HF; Shen, L | 1 |
Chung, YI; Ha, JK; Kim, HJ; Kim, JH; Kim, TH; Kim, YH; Lee, BD; Lee, YM; Moon, E; Mun, CW; Park, JM | 1 |
Kalani, A; Kamat, PK; Kyles, P; Tyagi, N | 1 |
Bonuccelli, U; Bosco, P; Coppedè, F; Haslberger, A; Migliore, L; Petrozzi, L; Ragalmuto, A; Salluzzo, MG; Siciliano, G; Stoccoro, A; Tannorella, P; Tognoni, G | 1 |
Atienza, M; Cantero, JL; Llado-Saz, S | 1 |
Fenech, M; Thomas, P | 1 |
Albaladejo, MD; Morillas-Ruiz, JM; Rubio-Perez, JM; Vidal-Guevara, ML; Zafrilla, P | 1 |
Dar, TA; Kumar, T; Sharma, GS; Singh, LR | 1 |
Chwedorowicz, A; Chwedorowicz, R; Gustaw Rothenberg, K; Raszewski, G | 1 |
Hao, F; Hu, Q; Li, J; Teng, W; Wang, N | 1 |
Bäckman, L; Ertl-Wagner, B; Fratiglioni, L; Hooshmand, B; Kalpouzos, G; Kåreholt, I; Kivipelto, M; Laukka, EJ; Mangialasche, F; Mühlmann, M; Refsum, H; Smith, AD; Solomon, A; Wang, R | 1 |
Glick, JL; McMillan, PA | 1 |
Cui, Y; Kong, X; Wei, W; Wei, Y; Zhang, J; Zheng, L | 1 |
Narr, KL; Roussotte, FF; Small, GW; Thompson, PM | 1 |
Coppedè, F; Grossi, E; Migliore, L; Stoccoro, A; Tannorella, P | 1 |
Gao, XJ; Gong, JB; Ma, J; Qian, LJ; Wang, SD; Xie, F; Zhang, L; Zhao, Y | 1 |
Grant, WB | 1 |
Hasegawa, T; Ukai, W | 1 |
Nichols, J | 1 |
Beiser, AS; Benjamin, EJ; Chen, TC; Kaess, B; Preis, SR; Rahman, F; Satizabal, C; Seshadri, S; Vasan, RS; Weinstein, G | 1 |
Cui, XP; Mu, JS; Ye, JX; Zhang, DM | 1 |
Oláh, E; V Oláh, A; Varga, P | 1 |
Fuchs, D; Greilberger, J; Greilberger, M; Koidl, C; Lamprecht, M; Leblhuber, F; Oettl, K; Schroecksnadel, K | 1 |
Shea, TB; Tchantchou, F | 1 |
Gustafson, L; Hultberg, B; Nilsson, K | 9 |
Aisen, PS; Bottiglieri, T; Diaz-Arrastia, R; Jin, S; Sano, M; Schneider, LS; Stokes, KT; Thal, LJ; Thomas, RG; van Dyck, CH; Weiner, MF | 1 |
Bennett, DA; Clarke, RJ | 1 |
Cao, D; Desmond, R; Lah, JJ; Levey, AI; Li, L; Rahman, A; Zamrini, E | 1 |
Lucassen, PJ; Marlatt, MW; Perry, G; Smith, MA; Zhu, X | 1 |
Green, R; Luchsinger, JA; Mayeux, R; Miller, J; Tang, MX | 1 |
Huang, H; Jiang, P; Liu, XQ; Yan, Y | 1 |
Barcikowska, M; Chodakowska-Zebrowska, M; Czapski, GA; Gabryelewicz, T; Karciauskas, G; Kobryś, M; Pfeffer, A; Religa, D; Strosznajder, JB; Styczyńska, M | 1 |
de la Plata, CM; Diaz-Arrastia, R; Fields, BA; Gong, YH; Hynan, LS; Qu, BX; Rosenberg, RN; Weiner, MF; Womack, KB | 1 |
Almeida, S; Cascalheira, JF; Castro, R; Domingues, FC; Faria, MC; João, SS; Palmeira, M; Pinhanços, SS | 1 |
Dai, D; Li, K; Liu, S; Wang, B; Yao, L; Yao, S | 1 |
Bednarska-Makaruk, M; Bochyńska, A; Graban, A; Lipczyńska-Łojkowska, W; Rodo, M; Ryglewicz, D; Wehr, H | 1 |
Ochudło, S; Opala, G; Siuda, J; Targosz-Gajniak, M | 1 |
Pratico, D | 1 |
Machanic, BI | 1 |
Colla, M; Endres, M; Kronenberg, G | 1 |
Annerbo, S; Bäckman, L; Fratiglioni, L; Hultdin, J; Kivipelto, M; Lökk, J; Viitanen, M | 1 |
Beaumont, H; Jacoby, R; King, E; Oulhaj, A; Refsum, H; Smith, AD; Williams, J | 1 |
Hiraoka, M; Kagawa, Y; Kageyama, M | 1 |
Cvetanovska, G; Frommann, I; Jessen, F; Kölsch, H; Kornhuber, J; Lewczuk, P; Linnebank, M; Maier, W; Popp, J; Smulders, Y | 1 |
Humpel, C; Pirchl, M | 1 |
Baboolal, N; Davis, G; McRae, A; Nayak, S | 1 |
Annerbo, S; Kivipelto, M; Lokk, J | 1 |
Alajbegovic, A; Fajkic, A; Hadzovic-Dzuvo, A; Kulo, A; Lepara, D; Lepara, O; Nakas-Icindic, E; Sofic, E; Valjevac, A; Zaciragic, A | 1 |
Gould, TJ; Kruger, WD; Portugal, GS; Pratico, D; Wang, H; Zhuo, JM | 1 |
Abe, T; Isobe, C; Terayama, Y | 1 |
Escobedo, JO; Lim, S; Samoei, GK; Sibrian-Vazquez, M; Strongin, RM | 1 |
Hasegawa, T; Kitazawa, M; LaFerla, FM; Mikoda, N | 1 |
Chang, RC; Ho, YS; So, KF; Yang, XF; Yu, MS; Yuen, WH | 1 |
Griffiths, HR; Li, L; Nelles, G; Polidori, MC; Sies, H; Stahl, W; Willets, RS | 1 |
Jang, Y; Kwon, YH; Park, YJ | 1 |
Bosco, P; Cento, RM; Costantini, B; Ferri, R; Lanzone, A; Macrì, F; Perri, C; Proto, C; Suriano, R; Villa, P | 1 |
Cornelli, U | 1 |
Prakasam, A; Ramesh, BN; Rao, KS; Rao, TS; Sambamurti, K | 1 |
Borroni, B; Conti, E; Ferrarese, C; Galimberti, G; Isella, V; Padovani, A; Perlangeli, MV; Piazza, F; Pogliani, EM; Speranza, T | 1 |
Lovestone, S; Thambisetty, M | 1 |
Hudson, PR; McCaddon, A | 1 |
Chang, PY; Chen, CH; Lu, SC | 1 |
Handels, R; van Rossum, IA; Visser, PJ; Vos, S | 1 |
Aisen, PS; Blennow, K; Clark, CM; Dean, R; Jack, CR; Jagust, W; Korecka, M; Lee, VM; Lewczuk, P; Petersen, RC; Potter, WZ; Shaw, LM; Siemers, E; Simon, A; Soares, H; Toga, AW; Trojanowski, JQ; Vandeerstichele, H; Weiner, MW | 1 |
Chang, CC; Chang, WN; Chen, C; Chen, CF; Huang, CW; Juang, YY; Lin, YT; Lu, CH; Lui, CC; Tu, MC; Wang, YL | 1 |
Blom, H; Cvetanovska, G; Farkas, M; Jessen, F; Kölsch, H; Kulic, L; Linnebank, M; Popp, J; Semmler, A; Smith, D; Smulders, Y; Stoffel-Wagner, B; Weller, M | 1 |
Basu, S; Chakrabarti, S; Pal, K; Saha, A; Sinha, M | 1 |
Chen, CS; Chou, MC; Lai, CL; Liao, YC; Liu, CK; Yang, YH; Yeh, YC; Yen, CF | 1 |
Gong, YH; Hynan, LS; Qu, BX; Rosenberg, RN; Rossetti, H; Weiner, MF; Womack, KB | 1 |
Chang, CC; Chang, WN; Chen, C; Chen, CF; Chen, NC; Huang, CW; Lin, YT; Lui, CC; Tu, MC; Wang, YL | 1 |
Sui, R; Zhang, L | 1 |
Albaladejo, MD; Morillas-Ruiz, JM; Parra, S; Rubio-Perez, JM; Vidal-Guevara, ML; Zafrilla, P | 1 |
Adachi, K; Akatsu, H; Hosono, T; Jung, CG; Komano, H; Michikawa, M; Minagawa, H; Ohtsuka, C; Takahashi, S; Terayama, Y; Wakita, H; Watanabe, A | 1 |
Ahtiluoto, S; Hooshmand, B; Kåreholt, I; Kivipelto, M; Laatikainen, T; Leiviskä, J; Rusanen, M; Soininen, H; Solomon, A; Winblad, B | 1 |
Fuchs, D; Greilberger, J; Greilberger, M; Leblhuber, F; Tafeit, E; Wintersteiger, R | 1 |
Ahmed, HH | 1 |
Choi, KC; Kwok, T; Lam, LC; Law, CB; Lee, J; Pan, PC; Yung, CY | 1 |
Sachdev, PS | 1 |
Ben Othman, L; Bennamou, S; Charfeddine, B; Dridi, H; Golmard, JL; Jacob, N; Lammouchi, T; Limem, K; Smach, MA | 1 |
Hua, X; Jack, CR; Rajagopalan, P; Thompson, PM; Toga, AW; Weiner, MW | 1 |
Callahan, CM; Hendrie, HC | 1 |
Praticò, D; Wang, H; Zhuo, JM | 1 |
Cheung, MW; Fu, E; Ho, RC; Mak, A; Ng, A; Win, HH; Zaw, MH | 1 |
Broadbent, D; Gurton, J; Houston, L; Moore, V; Nilforooshan, R; Tabet, N; Weaving, G | 1 |
Ames, D; Bush, AI; Ellis, KA; Faux, NG; Fowler, CJ; Laws, SM; Martins, RN; Masters, CL; Pertile, KK; Porter, L; Rembach, A; Rowe, CC; Rumble, RL; Szoeke, C; Taddei, K; Taddei, T; Trounson, BO; Villemagne, VL; Ward, V | 1 |
Chen, Z; Guo, ZY; Hu, J; Liu, D; Tan, L; Wang, JZ; Wang, Q; Zhao, N; Zhou, P; Zhu, LQ | 1 |
Caldarazzo lenco, E; Coppedè, F; Migheli, F; Migliore, L; Monzani, F; Nacmias, B; Pezzini, I; Piaceri, I; Polini, A; Ricci, G; Siciliano, G; Sorbi, S; Tannorella, P | 1 |
Chang, YS; Chen, CS; Huang, MF; Yeh, YC | 1 |
Alexopoulos, P; Bickel, H; Kurz, A; Perneczky, R | 1 |
Ahmadian, S; Aryapour, H; Hoveizi, E; Karima, O; Khodadadi, S; Riazi, GH | 1 |
Abbiati, V; Emanuele, E; Martinelli, V; Ricevuti, G | 1 |
Borowczyk, K; Jakubowski, H; Shih, DM | 1 |
Jagust, WJ; Lo, RY | 1 |
Fujishiro, H; Hasegawa, T; Hatano, T; Hattori, N; Ichiba, M; Iseki, E; Kasanuki, K; Matsumoto, SE; Tabira, T; Yamada, T | 1 |
Jakubowski, H; Perła-Kaján, J | 1 |
Arlt, S; Böger, RH; Jahn, H; Jessen, F; Kölsch, H; Linnebank, M; Popp, J; Schwedhelm, E; Smulders, Y | 1 |
Chang, N; Kim, G; Kim, H; Kim, KN; Kim, SY; Son, JI; Tamura, T | 1 |
Arıoğul, S; Cankurtaran, ES; Cankurtaran, M; Halil, M; Kuyumcu, ME; Oztürk, ZA; Ulger, Z; Yavuz, BB; Yesil, Y | 1 |
Morris, MS | 2 |
Chai, GS; Cheng, XS; Jiang, X; Liu, GP; Ma, ZW; Ni, ZF; Wang, JZ; Wang, Q; Xie, AJ | 1 |
Cacciapuoti, F | 1 |
Czapski, GA; Maruszak, A; Safranow, K; Strosznajder, JB; Styczyńska, M; Żekanowski, C | 1 |
Sano, M | 1 |
Korczyn, AD | 1 |
Dynan, KB; Lawson, JT; McIlroy, SP; Passmore, AP; Patterson, CC | 1 |
Agosti, C; Borroni, B; Di Luca, M; Padovani, A; Panzali, AF | 1 |
Lyons-Weiler, J; Rogers, E; Shea, TB | 1 |
O'Connell, TC; Williams, JH | 1 |
Breteler, MM; Clarke, R; den Heijer, T; Hofman, A; Koudstaal, PJ; Oudkerk, M; Vermeer, SE | 1 |
Barber, J; Davies, G; Hill, D; Hudson, P; Lloyd, A; McCaddon, A; Regland, B | 1 |
Mattson, MP; Shea, TB | 1 |
Mattson, MP | 1 |
Miller, AL | 1 |
Leboeuf, R | 1 |
Bleich, S; Falkai, P; Kessler, H; Supprian, T | 1 |
Blom, HJ; Bosma, H; Bosmans, E; De Bruijn, C; de Vente, J; Delanghe, J; Jolles, J; Lütjohann, D; Maes, M; Steinbusch, HW; Teunissen, CE; van Boxtel, MP; von Bergmann, K; Wauters, A | 1 |
Chan, SL; Mattson, MP; Pak, KJ | 1 |
Debanne, SM; Friedland, RP; Jacobsen, DW; Lerner, AJ; Mizrahi, EH; Petot, GJ; Traore, F | 1 |
Barcikowska, M; Chodakowska, M; Gabryelewicz, T; Golebiowski, M; Luczywek, E; Peplonska, B; Pfeffer, A; Religa, D; Stepien, K; Styczynska, M; Wasiak, B; Winblad, B | 1 |
Seshadri, S; Wolf, PA | 1 |
Bleich, S; Kornhuber, J; Wiltfang, J | 1 |
Selley, ML | 3 |
Peskin, ER; Pfeiffer, EA; Porsteinsson, AP; Schneider, LS | 1 |
Costa, M; Hoff, AL; Sommer, BR | 1 |
Czeizel, E; Kalina, A | 1 |
Religa, D; Winblad, B | 1 |
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Anello, G; Bosco, P; Caraci, F; Daval, JL; Ferri, R; Guéant, JL; Guéant-Rodríguez, RM; Namour, B; Pourié, G; Romano, A; Spada, R | 1 |
Marcusson, J; Nägga, K; Rådberg, C | 1 |
Isoe-Wada, K; Kowa, H; Kusumi, M; Nakashima, K; Nakaso, K; Takeshima, T; Urakami, K; Wakutani, Y; Yano, H; Yasui, K | 1 |
Qi, JS; Qiao, JT; Qin, Y | 1 |
Dwyer, BE; Perry, G; Raina, AK; Smith, MA | 1 |
Arai, H; Maruyama, M; Matsui, T; Nemoto, M; Ootsuki, M; Sasaki, H; Tanji, H; Tomita, N | 1 |
Combrinck, M; Hogervorst, E; Smith, AD; van Osch, LA | 1 |
Green, R; Luchsinger, JA; Mayeux, R; Miller, J; Shea, S; Tang, MX | 1 |
Anello, G; Bosco, P; Caraci, F; Ferri, R; Guéant, JL; Guéant-Rodríguez, RM; Namour, B; Romano, A; Spada, RS; Tringali, G | 1 |
Acres, J; Almeida, OP; Flicker, L; Jamrozik, K; Martins, RN; Norman, P; Taddei, K; Thomas, J | 1 |
Bicíková, M; Hampl, R; Havlíková, H; Hill, M; Jirák, R; Rípová, D; Tallová, J | 1 |
Forloni, G; Fragiacomo, C; Lucca, U; Pezzati, R; Quadri, P; Tettamanti, M; Zanda, E | 1 |
Davies, G; Duguid, J; Gray, R; Hill, D; Hudson, P; McCaddon, A; Tandy, S | 1 |
Fowler, B; Heun, R; Jeub, M; Klockgether, T; Koch, HG; Kölsch, H; Linnebank, A; Linnebank, M; Suormala, T; Wüllner, U | 1 |
Alagona, G; Bella, R; Carnemolla, A; Ferri, R; Malaguarnera, M; Pennisi, G | 1 |
Agnati, LF; Antonelli, F; Cortelli, P; Fuxe, K; Galantucci, M; Genedani, S; Guidolin, D; Rasio, G | 1 |
Adunsky, A; Bowirrat, A; Debanne, SM; Dibello, PM; Friedland, RP; Jacobsen, DW; Korczyn, AD; Lerner, AJ; Mizrahi, EH; Petot, GJ; Traore, F | 1 |
Agnati, LF; Ferré, S; Filaferro, M; Franco, R; Fuxe, K; Galantucci, M; Genedani, S; Mora, F; Rasio, G; Saltini, S | 1 |
Cavallaro, RA; D'Anselmi, F; Fuso, A; Scarpa, S; Seminara, L | 1 |
Harbrecht, U; Hentschel, F; Heun, R; Jessen, F; Kölsch, H; Kreis, M; Linnebank, M; Lütjohann, D; Maier, W; Schulz, A; Thelen, KM; von Bergmann, K; Wüllner, U | 1 |
Huang, MH; Kado, DM; Karlamangla, AS; Rowe, JW; Seeman, TE; Selhub, J; Troen, A | 1 |
Bresolin, N; Comi, GP; Del Bo, R; Dominici, R; Fenoglio, C; Forloni, G; Galbiati, S; Galimberti, D; Gatti, A; Guidi, I; Lovati, C; Mariani, C; Pomati, S; Scarpini, E; Venturelli, E; Virgilio, R | 1 |
Andrews, LG; Liu, L; Tollefsbol, TO; Ulrey, CL | 1 |
Anello, G; Barone, C; Bosco, P; Gérard, P; Guéant, JL; Guéant-Rodríguez, RM; Romano, A; Romano, C | 1 |
Araki, W; Hasegawa, T; Jo, DG; Mattson, MP; Nakagawa, M; Saito, T; Ukai, W; Xu, X; Yamada, T | 1 |
Domínguez, RO; Famulari, AL; Guareschi, EM; Marschoff, ER; Pagano, MA; Serra, JA | 1 |
Isobe, C; Murata, T; Sato, C; Terayama, Y | 1 |
Flirski, M; Sobow, T | 1 |
Bindels, JG; Blom, HJ; de Groot, LC; Hoefnagels, WH; Manders, M; van Staveren, WA; Vasse, E | 1 |
Almeida, OP; Flicker, L; Lautenschlager, NT; Leedman, P; Vasikaran, S | 1 |
Annerbo, S; Lökk, J; Wahlund, LO | 1 |
Brunetti, N; Forti, P; Licastro, F; Maioli, F; Martelli, M; Porcellini, E; Ravaglia, G; Servadei, L | 1 |
Dwyer, BE; Perry, G; Smith, MA; Takeda, A; Zhu, X | 1 |
Nagy, Z | 1 |
Aupetit, J; Janel, N; Santiard-Baron, D | 1 |
Arning, E; Barbé, F; Bottiglieri, T; Franck, P; Montagne, P; Nicolas, JP; Serot, JM | 1 |
Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M | 1 |
Bastagli, L; Bianchin, M; Bolondi, L; Chiappelli, M; Licastro, F; Maioli, F; Martelli, M; Montesi, F; Paola, F; Ravaglia, G; Tumini, E | 1 |
McCaddon, A; Regland, B | 1 |
Baiguera, S; Conconi, MT; Di Liddo, R; Folin, M; Gallucci, M; Parnigotto, PP; Zanardo, A | 1 |
Ke, XY; Liu, Y; Shen, W; Zhang, YD | 1 |
Cruz-Sanchez, F; DeRosa, S; Howard, A; Pacheco-Quinto, J; Pappolla, MA; Petanceska, S; Refolo, L; Rodriguez de Turco, EB; Sambamurti, K | 1 |
Selhub, J | 1 |
Thompson, J | 1 |
Bauer, K; Fischer, P; Huber, K; Jungwirth, S; Tragl, KH; Zehetmayer, S | 1 |
Arai, H; Furukawa, K; Higuchi, S; Iwasaki, K; Maruyama, M; Matsui, T; Matsushita, S; Nemoto, M; Ootsuki, M; Seki, T; Tanji, H; Tomita, N; Yao, H; Yoshida, Y; Yuzuriha, T | 1 |
Shea, TB | 1 |
McCaddon, A | 1 |
Seshadri, S | 1 |
Arai, H | 1 |
Agnati, LF; Filaferro, M; Forni, A; Franco, R; Fuxe, K; Genedani, S; Leo, G; Woods, AS | 1 |
Iversen, SA; Lyons, B; Rafi, H; Tabet, N; Weaving, G | 1 |
Sato, Y | 1 |
Cabral-Filho, JE; Cavalcanti, MN; D'Almeida, V; da Silva, VC; de Brito-Marques, PR; Freitas, EM; Muniz, MT; Ramos, FJ | 1 |
Anello, G; Babiloni, C; Bartesaghi, S; Benussi, L; Binetti, G; Bosco, P; Cassetta, E; Del Percio, C; Ferri, R; Frisoni, G; Ghidoni, R; Gurzì, M; Lanuzza, B; Lizio, R; Rossini, PM; Squitti, R; Tombini, M | 1 |
Archetti, S; Borroni, B; Cesana, BM; Ferrari, M; Padovani, A | 1 |
Hasegawa, T | 1 |
Boldyrev, AA; Johnson, P | 1 |
Karaman, Y; Köseoglu, E | 1 |
Barkhof, F; Blankenstein, MA; Bouwman, F; Jakobs, C; Mulder, C; Scheltens, P; van der Flier, WM; Veerhuis, R; Verhoeven, NM | 1 |
Bonham, J; Connelly, PJ; Cousland, G; Prentice, NP | 1 |
Chan, A; Chen, S; Rogers, EJ | 1 |
Baboolal, NS; Davis, GK; McKell, S; McRae, A; Ramchandani, J; Seales, D | 1 |
Luchsinger, JA; Noble, JM; Scarmeas, N | 1 |
Cavallaro, RA; Confaloni, A; D'Anselmi, F; Fuso, A; Piscopo, P; Scarpa, S; Zampelli, A | 1 |
Kim, JM; Kim, SW; Shin, HY; Shin, IS; Stewart, R; Yang, SJ; Yoon, JS | 2 |
Dwolatzky, T; Kaplan, Z; Kotler, M; Levine, J; Roitman, S; Sela, BA; Spivak, B; Timinsky, I; Vishne, T | 1 |
Luo, Y; Wang, J; Yang, X; Zhou, X | 1 |
Chen, RC; Chen, ST; Chien, KL; Lu, CJ; Sun, Y | 1 |
Das, UN | 1 |
Toohey, JI | 1 |
De la Fuente, M; Frank, A; Hernanz, A; Navarro, M | 1 |
Bi, XH; Zhang, JW; Zhang, ZX; Zhao, HL | 1 |
Cho, HK; Kim, HJ; Kwon, YH | 1 |
Antolini, L; Conti, E; DeFilippi, F; Facheris, M; Fenaroli, F; Ferrarese, C; Galimberti, G; Isella, V; Perlangeli, V; Piazza, F; Zini, M | 1 |
Hagnelius, NO; Nilsson, TK; Wahlund, LO | 1 |
Dejaeger, E; Dereymaeker, L; Ghekiere, V; Joosten, E; Lesaffre, E; Pelemans, W; Riezler, R | 1 |
Cattell, H; Davies, G; Hudson, P; McCaddon, A; Tandy, S | 1 |
Clarke, R; Jobst, KA; Refsum, H; Smith, AD; Sutton, L; Ueland, PM | 1 |
Miller, JW | 1 |
Breteler, MM | 1 |
Barnetson, L; Budge, M; Bungay, H; Clarke, R; Esiri, M; Frost, C; Joachim, C; King, E; Molyneux, A; Morris, J; Smith, AD | 1 |
Bejarano-Achache, I; Blumenfeld, A; Doron, D; Idelson, M; Pollak, A; Pollak, RD | 1 |
Adoue, D; Albarède, JL; Andrieu, S; Guyonnet, S; Nourhashémi, F; Ousset, PJ; Rolland, Y; Vellas, B | 1 |
Fäldt, R; Gustafson, L; Hultberg, B; Nilsson, K; Warkentin, S | 1 |
Bargossi, AM; Caldarera, M; Cavalli, G; Facchini, A; Forti, P; Franceschi, C; Grossi, G; Maioli, F; Mariani, E; Ravaglia, G; Vettori, C | 1 |
Beilby, J; Rossi, E | 1 |
Barrow, CJ; Beyreuther, K; Bush, AI; Cappai, R; Huang, X; Jobling, MF; Masters, CL; White, AR | 1 |
Artner-Dworzak, E; Fuchs, D; Leblhuber, F; Reibnegger, G; Vrecko, K; Walli, J; Widner, B | 1 |
Rosenberg, IH | 1 |
Blennow, K; Gottfries, CG; Gottfries, J; Lehmann, MW; Regland, B | 1 |
González-Gross, M; Marcos, A; Pietrzik, K | 1 |
Joosten, E | 1 |
Loscalzo, J | 1 |
Beiser, A; D'Agostino, RB; Jacques, PF; Rosenberg, IH; Selhub, J; Seshadri, S; Wilson, PW; Wolf, PA | 1 |
Cutler, RG; Evans, M; Haughey, N; Kruman, II; Kruman, Y; Kumaravel, TS; Lee, J; Lohani, A; Mattson, MP; Pedersen, WA | 1 |
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Friedland, RP; Jacobsen, DW; Mizrahi, EH | 1 |
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Davies, G; Hudson, P; McCaddon, A; Regland, B | 1 |
Budge, M; Hogervorst, E; Molyneux, A; Ribeiro, HM; Smith, AD | 1 |
Green, R; Jagust, WJ; Miller, JW; Mungas, DM; Reed, BR | 1 |
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61 review(s) available for homocysteine and Alzheimer Disease
Article | Year |
---|---|
A disease-modifying treatment for Alzheimer's disease: focus on the trans-sulfuration pathway.
Topics: Alzheimer Disease; Animals; Homocysteine; Humans; Molybdenum; Neuroprotective Agents; Selenocysteine | 2020 |
Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction.
Topics: Aging; Alzheimer Disease; Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Endoplasmic Reticulum Stress; Homocysteine; Humans; Hyperhomocysteinemia; Macular Degeneration; Oxidative Stress | 2020 |
Abnormal Homocysteine Metabolism: An Insight of Alzheimer's Disease from DNA Methylation.
Topics: Aged; Alzheimer Disease; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Neurodegenerative Diseases | 2020 |
Association of
Topics: Adult; Aged; Alleles; Alzheimer Disease; Carbon; Child; Congenital Abnormalities; Female; Genotype; Homocysteine; Humans; Male; Methylmalonic Acid; Neoplasms; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2017 |
Dissecting the Role of 5-Lipoxygenase in the Homocysteine-Induced Alzheimer's Disease Pathology.
Topics: Alzheimer Disease; Animals; Arachidonate 5-Lipoxygenase; Brain; Epigenesis, Genetic; Homocysteine; Humans; Hyperhomocysteinemia | 2018 |
Causes of hyperhomocysteinemia and its pathological significance.
Topics: Alzheimer Disease; Anemia; Animals; Biomarkers; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2018 |
Hyperhomocysteinemia and risk of incident cognitive outcomes: An updated dose-response meta-analysis of prospective cohort studies.
Topics: Alzheimer Disease; Cognition; Cognitive Dysfunction; Cohort Studies; Dementia, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Prospective Studies; Risk Factors | 2019 |
Neuroenhancement with vitamin B12-underestimated neurological significance.
Topics: Alzheimer Disease; Brain; Cognition; Homocysteine; Humans; Incidence; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2013 |
Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis.
Topics: Alcohol Drinking; Alzheimer Disease; Antioxidants; Caffeine; Cognition; Cognition Disorders; Dementia; Diet; Educational Status; Exercise; Fatty Acids, Omega-3; Female; Homocysteine; Humans; Male; Smoking | 2014 |
Folate and homocysteine metabolisms and their roles in the biochemical basis of neuropsychiatry.
Topics: Alzheimer Disease; Autistic Disorder; Biological Transport; Folic Acid; Homocysteine; Humans; Psychotic Disorders | 2014 |
Associations between Homocysteine, Folic Acid, Vitamin B12 and Alzheimer's Disease: Insights from Meta-Analyses.
Topics: Age Factors; Alzheimer Disease; Databases, Bibliographic; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2015 |
Protein N-homocysteinylation: From cellular toxicity to neurodegeneration.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Homocysteine; Humans; Neurodegenerative Diseases; Neurons; Prions; Protein Aggregates | 2015 |
Homocysteine and Alzheimer's Disease: Evidence for a Causal Link from Mendelian Randomization.
Topics: Alzheimer Disease; Data Interpretation, Statistical; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide | 2016 |
Using Multicountry Ecological and Observational Studies to Determine Dietary Risk Factors for Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholesterol; Cooking; Culture; Dairy Products; Diet; Diet, Western; Dietary Carbohydrates; Dietary Fats; Ecology; Glycation End Products, Advanced; Homocysteine; Hot Temperature; Humans; Meat; Metals; Obesity; Oxidative Stress; Risk Factors; Vitamin D | 2016 |
Efficacy of Vitamin B Supplementation on Cognition in Elderly Patients With Cognitive-Related Diseases.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2017 |
[Biochemical alterations in patients with Down syndrome].
Topics: Acetylglucosaminidase; Adult; Alzheimer Disease; Antioxidants; Bilirubin; Blood Proteins; Cystathionine beta-Synthase; Disease Progression; Down Syndrome; Ferritins; Folic Acid; Homocysteine; Humans; Learning; Nootropic Agents; Quality of Life; S100 Proteins; Serum Albumin; Superoxide Dismutase; Transferrin; Vitamin B 12 | 2008 |
Plasma homocysteine and vascular disease in elderly patients with mental illness.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Dementia; Homocysteine; Humans; Mental Disorders; Risk Factors; Vascular Diseases | 2008 |
Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies.
Topics: Alzheimer Disease; Cerebrovascular Disorders; Clinical Trials as Topic; Dementia; Homocysteine; Humans; Neurodegenerative Diseases; Oxidative Stress | 2008 |
Folic acid, neurodegenerative and neuropsychiatric disease.
Topics: Aging; Alzheimer Disease; Animals; Brain; Clinical Trials as Topic; Dementia, Vascular; Depression; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Molecular Structure; Neurodegenerative Diseases; Neuronal Plasticity; Stroke; Vitamin B Complex | 2009 |
Neuronutrition and Alzheimer's disease.
Topics: Aged; Alcohol Drinking; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Avitaminosis; Brain; Diet; Energy Intake; Female; Homocysteine; Humans; Hypercholesterolemia; Male; Middle Aged; Nerve Degeneration; Nutrition Therapy; Oxidative Stress; Phosphorylation; Point Mutation; Vitamin E | 2010 |
Blood-based biomarkers of Alzheimer's disease: challenging but feasible.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; C-Reactive Protein; Genetic Markers; Homocysteine; Humans; Longitudinal Studies; Proteomics; RNA | 2010 |
L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline.
Topics: Acetylcysteine; Alzheimer Disease; Cognition Disorders; Free Radical Scavengers; Homocysteine; Humans; Oxidative Stress; Plaque, Amyloid; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex | 2010 |
Biomarkers as predictors for conversion from mild cognitive impairment to Alzheimer-type dementia: implications for trial design.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Clinical Trials as Topic; Cognition Disorders; Disease Progression; Homocysteine; Humans; Lipid Metabolism; Peptide Fragments; tau Proteins | 2010 |
Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Biomarkers; Cognition Disorders; Cross-Sectional Studies; Diagnostic Imaging; Homocysteine; Humans; Isoprostanes; Peptide Fragments; Positron-Emission Tomography; Prospective Studies; Reproducibility of Results; tau Proteins; Thiazoles | 2010 |
Is hyperhomocysteinemia an Alzheimer's disease (AD) risk factor, an AD marker, or neither?
Topics: Alzheimer Disease; Animals; Biomarkers; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2011 |
Is high homocysteine level a risk factor for cognitive decline in elderly? A systematic review, meta-analysis, and meta-regression.
Topics: Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Regression Analysis; Risk Factors; Vitamin B 12 | 2011 |
Linking atherosclerosis to Alzheimer's disease: focus on biomarkers.
Topics: Alzheimer Disease; Atherosclerosis; Biomarkers; C-Reactive Protein; Cystatin C; Homocysteine; Humans; Lipoprotein(a); Osteoprotegerin; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2012 |
Paraoxonase 1 and homocysteine metabolism.
Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Atherosclerosis; Coronary Artery Disease; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipoproteins, HDL; Mice; Oxidative Stress; Stroke | 2012 |
The role of B vitamins in preventing and treating cognitive impairment and decline.
Topics: Alzheimer Disease; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylation; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Lowering homocysteine levels with folic acid and B-vitamins do not reduce early atherosclerosis, but could interfere with cognitive decline and Alzheimer's disease.
Topics: Alzheimer Disease; Atherosclerosis; Cognition; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2013 |
Prevention of Alzheimer's disease: where we stand.
Topics: Alzheimer Disease; Anti-Inflammatory Agents; Cognition; Estrogen Replacement Therapy; Female; Ginkgo biloba; Homocysteine; Humans; Lipid Metabolism; Male; Primary Prevention | 2002 |
Homocysteine, folate deprivation and Alzheimer neuropathology.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Nerve Degeneration | 2002 |
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke | 2003 |
The methionine-homocysteine cycle and its effects on cognitive diseases.
Topics: Alzheimer Disease; Cardiovascular Diseases; Cognition Disorders; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Memory Disorders; Methionine; Methionine Adenosyltransferase; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2003 |
Homocysteine and Alzheimer's disease.
Topics: Age Factors; Aged; Alzheimer Disease; Apolipoproteins E; Brain; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Nutrition Policy; Risk Factors; Sex Factors; United States; Vitamin B 12; Vitamin B 6 | 2003 |
[Homocysteine and dementia].
Topics: Alzheimer Disease; Biomarkers; Cerebral Amyloid Angiopathy; Dementia; Dementia, Vascular; Disease Progression; Homocysteine; Humans; Risk Factors | 2003 |
Homocysteine and Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Homocysteine; Hyperhomocysteinemia; Risk Factors | 2003 |
Choosing treatment for Alzheimer's patients and their caregivers.
Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents; Anticonvulsants; Antipsychotic Agents; Caregivers; Cholinesterase Inhibitors; Depression; Ginkgo biloba; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phytotherapy; Plant Extracts; Professional-Family Relations; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Risk Factors; Social Support; Vitamin E | 2003 |
[Public health control of hyperhomocysteinemia and its consequences].
Topics: Alzheimer Disease; Canada; Cardiovascular Diseases; Flour; Folic Acid; Food, Fortified; Hematinics; Homocysteine; Humans; Hungary; Hyperhomocysteinemia; Neoplasms; Neural Tube Defects; Primary Prevention; Public Health; Randomized Controlled Trials as Topic; United Kingdom; United States; Vitamin B Complex; Vitamin B Deficiency | 2003 |
Therapeutic strategies for Alzheimer's disease based on new molecular mechanisms.
Topics: Alzheimer Disease; Amyloidosis; Cholinesterase Inhibitors; Homocysteine; Humans | 2003 |
[Homocysteine and neuropsychiatric disorders].
Topics: Alzheimer Disease; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mental Disorders; Parkinson Disease; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6 | 2004 |
[Homocysteine and Alzheimer's disease].
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Homocysteine; Humans; Hyperhomocysteinemia | 2004 |
The impact of metabolism on DNA methylation.
Topics: Alzheimer Disease; Animals; Arteriosclerosis; DNA Methylation; Folic Acid; Gene Expression Regulation; Glycine N-Methyltransferase; Homocysteine; Humans; Methionine; Methyltransferases; Models, Biological; S-Adenosylmethionine | 2005 |
Biochemical markers and risk factors of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholesterol; Cytokines; Free Radicals; Homocysteine; Humans; Inflammation; Oxidation-Reduction; Oxidative Stress; Phosphorylation; tau Proteins | 2005 |
Ferric cycle activity and Alzheimer disease.
Topics: Alzheimer Disease; Animals; Brain Chemistry; Cell Cycle; Heme; Homocysteine; Humans; Iron; Models, Biological; Oxidative Stress | 2005 |
Interleukin-1beta and interleukin-6 gene polymorphisms as risk factors for AD: a prospective study.
Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Dementia; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Interleukin-1; Interleukin-6; Male; Polymorphism, Genetic; Prospective Studies; Risk Factors | 2006 |
The many facets of hyperhomocysteinemia: studies from the Framingham cohorts.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Massachusetts; Middle Aged; Risk Factors; Stroke; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
Vitamins and minerals 4: overview of folate and the B vitamins.
Topics: Alzheimer Disease; Cardiovascular Diseases; Chemoprevention; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neoplasms; Primary Prevention; Risk Factors; Risk Reduction Behavior; Vitamin B 12; Vitamin B 6 | 2006 |
Homocysteine and cognition--a historical perspective.
Topics: Alzheimer Disease; Anemia, Pernicious; Cognition Disorders; Folic Acid Deficiency; History, 19th Century; History, 20th Century; History, 21st Century; Homocysteine; Humans; Vitamin B 12 Deficiency | 2006 |
Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease?
Topics: Alzheimer Disease; Dementia; Homocysteine; Humans; Risk Assessment; Risk Factors | 2006 |
[Importance of vascular aspects in Alzheimer's disease].
Topics: Accidental Falls; Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cause of Death; Cerebral Infarction; Diabetes Complications; Homocysteine; Humans; Hyperlipidemias; Hypertension; Life Style; Pneumonia, Aspiration; Risk Factors | 2006 |
[Immobilization and hip fracture].
Topics: Aged; Alzheimer Disease; Bone Density; Female; Hip Fractures; Homocysteine; Humans; Immobilization; Randomized Controlled Trials as Topic; Vitamin K | 2006 |
Homocysteine and its derivatives as possible modulators of neuronal and non-neuronal cell glutamate receptors in Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Calcium; Cell Death; Free Radicals; Homocysteine; Humans; Lymphocytes; Neurons; Oxidative Stress; Reactive Oxygen Species; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2007 |
Diet and Alzheimer's disease.
Topics: Alzheimer Disease; Antioxidants; Brain; Caloric Restriction; Diet Therapy; Dietary Fats; Food, Formulated; Homocysteine; Humans; Oxidative Stress; Randomized Controlled Trials as Topic; Vitamins | 2007 |
Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer's disease--but how and why?
Topics: Alzheimer Disease; Animals; Arachidonic Acid; Cognition; Dementia; Depression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Folic Acid; Homocysteine; Humans; Inflammation Mediators; Nitric Oxide | 2008 |
Homocysteine and Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Homocysteine; Humans; Logistic Models; Risk Factors | 1999 |
Number 58: homocysteine and disease.
Topics: Alzheimer Disease; Animals; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Diet; Folic Acid; Homocysteine; Humans; Neural Tube Defects | 2000 |
B vitamins, homocysteine, and neurocognitive function.
Topics: Aging; Alzheimer Disease; Cognition Disorders; Gastritis, Atrophic; Homocysteine; Humans; Nutritional Status; Vitamin B Deficiency | 2001 |
Nutrition and cognitive impairment in the elderly.
Topics: Aged; Aging; Alzheimer Disease; Antioxidants; Avitaminosis; Dementia; Dementia, Vascular; Dietary Supplements; Educational Status; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hypertension; Life Style; Nutritional Physiological Phenomena; Nutritional Status; Risk Factors; Stroke; Vitamin B 12 Deficiency | 2001 |
Homocysteine, vascular dementia and Alzheimer's disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Double-Blind Method; Folic Acid; Homocysteine; Humans; Middle Aged; Placebos; Risk Factors; Time Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Plasma homocysteine: a new risk factor for Alzheimer's disease?
Topics: Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2002 |
17 trial(s) available for homocysteine and Alzheimer Disease
Article | Year |
---|---|
Clinical efficacy of acupuncture combined with Western medicine in the treatment of mild to moderate Alzheimer disease: A protocol of a randomized controlled trial.
Topics: Activities of Daily Living; Acupuncture Therapy; Alzheimer Disease; Donepezil; Double-Blind Method; Homocysteine; Humans; Prospective Studies; Randomized Controlled Trials as Topic; Single-Blind Method; Superoxide Dismutase; Treatment Outcome | 2022 |
Cross-sectional and prospective associations between homocysteine and a frailty index: A post-hoc analysis of the multidomain Alzheimer's prevention trial (MAPT).
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cross-Sectional Studies; Fatty Acids, Omega-3; Frailty; Homocysteine; Humans | 2023 |
Dietary intakes and biomarker patterns of folate, vitamin B
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Pyrophosphatases; Thioredoxin Reductase 1; Vitamin B 12; Vitamin B 6 | 2019 |
Association between malnutrition and hyperhomocysteine in Alzheimer's disease patients and diet intervention of betaine.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Betaine; Case-Control Studies; Dementia; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Memory; Nerve Tissue Proteins; Risk Factors | 2017 |
Cross-Sectional Associations of Total Plasma Homocysteine with Cortical β-Amyloid Independently and as a Function of Omega 3 Polyunsaturated Fatty Acid Status in Older Adults at Risk of Dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Cross-Sectional Studies; Dementia; Fatty Acids, Omega-3; Female; Homocysteine; Humans; Male; Risk Factors | 2017 |
Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study.
Topics: Aged; Alzheimer Disease; Cognition; Dietary Supplements; Fatty Acids, Omega-3; Female; Homocysteine; Humans; Male; Treatment Outcome | 2019 |
Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment.
Topics: Alzheimer Disease; Bayes Theorem; England; Hippocampus; Homocysteine; Humans; Image Processing, Computer-Assisted; Linear Models; Longitudinal Studies; Magnetic Resonance Imaging; Nerve Degeneration; Temporal Lobe; Vitamin B Complex | 2013 |
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Psychiatric Status Rating Scales; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Treatment of Alzheimer's disease with a cholinesterase inhibitor combined with antioxidants.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Bisphenol A-Glycidyl Methacrylate; Cholinesterase Inhibitors; Cohort Studies; Donepezil; Double-Blind Method; Drug Therapy, Combination; Female; Homocysteine; Humans; Indans; Male; Models, Biological; Oxidative Stress; Piperidines; Polyurethanes; Proteoglycans; Reactive Oxygen Species; Time Factors; Treatment Outcome | 2010 |
Effect of an antioxidant drink on homocysteine levels in Alzheimer's patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cross-Sectional Studies; Double-Blind Method; Female; Flavonoids; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Oxidative Stress; Phenols; Polyphenols; Statistics, Nonparametric; Treatment Outcome; Vitamin B 12 | 2010 |
A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Hong Kong; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Patient Dropouts; Vitamin B 12; Vitamin B Complex | 2011 |
Increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Arginine; Enzyme Inhibitors; Female; Homocysteine; Humans; Male; Matched-Pair Analysis; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Reference Values; Statistics as Topic | 2003 |
Folic acid supplementation in dementia: a preliminary report.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Prevalence; Risk Factors | 2003 |
Absence of macrocytic anaemia in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anemia, Macrocytic; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Platelet Count; Sex Factors; Vitamin B 12 | 2004 |
Influence of the Glu298Asp polymorphism of NOS3 on age at onset and homocysteine levels in AD patients.
Topics: Age Distribution; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Substitution; Female; Genetic Predisposition to Disease; Genetic Testing; Glutamine; Homocysteine; Humans; Italy; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Risk Assessment; Risk Factors; Statistics as Topic | 2005 |
A randomised double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Analysis of Variance; Chi-Square Distribution; Cholinesterase Inhibitors; Dietary Supplements; Donepezil; Double-Blind Method; Female; Folic Acid; Folic Acid Deficiency; Galantamine; Homocysteine; Humans; Indans; Male; Mental Status Schedule; Phenylcarbamates; Piperidines; Placebos; Rivastigmine; Treatment Outcome; Vitamin B Complex; Vitamins | 2008 |
Efficacy of multivitamin supplementation containing vitamins B6 and B12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: a 26-week, randomized, double-blind, placebo-controlled study in Taiwanese patients.
Topics: Aged; Alzheimer Disease; Asian People; Cholinesterase Inhibitors; Donepezil; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Indans; Male; Piperidines; Taiwan; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
268 other study(ies) available for homocysteine and Alzheimer Disease
Article | Year |
---|---|
The Link between Exercise and Homocysteine in the Alzheimer's Disease: A Bioinformatic Network Model.
Topics: Alzheimer Disease; Brain; Cognitive Dysfunction; Computational Biology; Exercise; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress | 2021 |
Association between homocysteine levels and cognitive profile in Alzheimer's Disease.
Topics: Alzheimer Disease; Cognition; Cross-Sectional Studies; Homocysteine; Humans; Neuropsychological Tests | 2021 |
Ameliorative Effect of Acetyl L-carnitine in Alzheimer's Disease via Downregulating of Homocysteine Levels in Hyperhomocysteinemia Induced Cognitive Deficit in Mouse Model.
Topics: Acetylcarnitine; Acetylcholinesterase; Alzheimer Disease; Animals; Cognition; Homocysteine; Hyperhomocysteinemia; Mice; Neuroinflammatory Diseases | 2021 |
Vitamin B12 as a cholinergic system modulator and blood brain barrier integrity restorer in Alzheimer's disease.
Topics: Alzheimer Disease; Blood-Brain Barrier; Cholinergic Agents; Folic Acid; Homocysteine; Humans; Receptors, Cholinergic; Vitamin B 12 | 2022 |
MiR-483-3p improves learning and memory abilities via XPO1 in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Exportin 1 Protein; Homocysteine; Karyopherins; MicroRNAs; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear | 2022 |
A Retrospective Study on Clinical Assessment of Cognitive Impairment in a Swedish Cohort: Is There Inequality Between Natives and Foreign-Born?
Topics: Albumins; Alzheimer Disease; Atrophy; Biomarkers; Calcium; Cognitive Dysfunction; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Retrospective Studies; Sweden; Thyrotropin; Vitamin B 12 | 2022 |
Diagnostic Values of Advanced Glycation End Products and Homocysteine in Patients with Alzheimer's Disease and Sarcopenia.
Topics: Aged; Alzheimer Disease; Glycation End Products, Advanced; Homocysteine; Humans; ROC Curve; Sarcopenia | 2022 |
Serum Homocysteine, Vitamin B12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia.
Topics: Alzheimer Disease; Cognitive Dysfunction; Dementia, Vascular; Folic Acid; Frontotemporal Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2022 |
Association of homocysteine-related subcortical brain atrophy with white matter lesion volume and cognition in healthy aging.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atrophy; Brain; Cognition; Cognitive Dysfunction; Healthy Aging; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; White Matter | 2023 |
Homocysteine - A predictor for five year-mortality in patients with subjective cognitive decline, mild cognitive impairment and Alzheimer's dementia.
Topics: Alzheimer Disease; Cognition; Cognitive Dysfunction; Disease Progression; Homocysteine; Humans; Neuropsychological Tests; Retrospective Studies | 2023 |
Diagnostic Value of ATG5, Apo-Lipoprotein B-48, Thyroid Hormones, and Homocysteine in Patients with Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Apolipoprotein B-48; Autophagy-Related Protein 5; Folic Acid; Homocysteine; Humans; Middle Aged; Thyroid Hormones; Vitamin B 12 | 2023 |
In Situ Fluorescence Imaging Reveals Contribution of Cerebral Hydroxyl Radicals in Hyperhomocysteinemia-Induced Alzheimer-like Dementia.
Topics: Alzheimer Disease; Animals; Homocysteine; Hydroxyl Radical; Hyperhomocysteinemia; Mice; Optical Imaging; Risk Factors | 2023 |
Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes.
Topics: Alzheimer Disease; Animals; Atorvastatin; Cognition; Cognitive Dysfunction; Dementia, Vascular; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Mice | 2023 |
Neurovascular Correlates of Cobalamin, Folate, and Homocysteine in Dementia.
Topics: Alzheimer Disease; Brain; Brain Ischemia; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2023 |
Association of Leukocyte Telomere Length with Mild Cognitive Impairment and Alzheimer's Disease: Role of Folate and Homocysteine.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Correlation of Data; Female; Folic Acid; Homocysteine; Humans; Leukocytes; Male; Middle Aged; Telomere Shortening | 2019 |
Plasma Apolipoprotein E Monomer and Dimer Profile and Relevance to Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Apolipoprotein A-II; Apolipoprotein E3; Apolipoprotein E4; Biomarkers; Cognitive Dysfunction; Female; Homocysteine; Homozygote; Humans; Male; Protein Structure, Quaternary; tau Proteins | 2019 |
The relationship between cognitive impairment and homocysteine in a B12 and folate deficient population in China: A cross-sectional study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; China; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; HEK293 Cells; Homocysteine; Humans; Male; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Sulfonamides | 2020 |
Homocysteine Induces Inflammation in Retina and Brain.
Topics: Alzheimer Disease; Animals; Brain; Diabetic Retinopathy; Homocysteine; Humans; Inflammation; Macular Degeneration; Mice; Mice, Knockout; Retina; U937 Cells | 2020 |
Serum homocysteine and risk of dementia in Japan.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Dementia, Vascular; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors | 2020 |
Effects of homocysteine and memantine on oxidative stress related TRP cation channels in
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Calcium; Caspase 3; Caspase 9; Female; Hippocampus; Homocysteine; Male; Memantine; Membrane Potential, Mitochondrial; Mice; Models, Biological; Neurons; Oxidative Stress; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Transient Receptor Potential Channels | 2021 |
Biological and Neuroimaging Markers as Predictors of 5-Year Incident Frailty in Older Adults: A Secondary Analysis of the MAPT Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; C-Reactive Protein; Fatty Acids, Omega-3; Frail Elderly; Frailty; Homocysteine; Humans; Neuroimaging | 2021 |
Levels of Vitamins and Homocysteine in Older Adults with Alzheimer Disease or Mild Cognitive Impairment in Cuba.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognitive Dysfunction; Cross-Sectional Studies; Cuba; Homocysteine; Humans; Vitamins | 2020 |
Hyperhomocysteinemia and Dementia Associated With Severe Cortical Atrophy, but No Amyloid Burden.
Topics: Aged; Alzheimer Disease; Atrophy; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 2022 |
Changes in Biothiol Levels Are Closely Associated with Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Biomarkers; Brain; Cysteine; Down-Regulation; Early Diagnosis; Female; Fluorescent Dyes; Glutathione; Homocysteine; Humans; Male; Mice; Middle Aged; PC12 Cells; Rats; Spectrometry, Fluorescence; Sulfhydryl Compounds; Up-Regulation; Vitamin B 6; Vitamin B Complex | 2021 |
Relationship of Homocysteine Plasma Levels with Mild Cognitive Impairment, Alzheimer's Disease, Vascular Dementia, Psychobehavioral, and Functional Complications.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Brief Psychiatric Rating Scale; Cognitive Dysfunction; Dementia, Vascular; Female; Homocysteine; Humans; Interviews as Topic; Male | 2021 |
Homocysteine fibrillar assemblies display cross-talk with Alzheimer's disease β-amyloid polypeptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Brain; Cell Death; Cell Line, Tumor; Disease Models, Animal; Homocysteine; Humans; Ion Mobility Spectrometry; Kinetics; Mice, Transgenic; Models, Biological; Polyphenols; Saccharomyces cerevisiae | 2021 |
Hypohomocysteinemia may increases the risk of dementia and Alzheimer's disease: A nationwide population-based prospective cohort study.
Topics: Aged; Alzheimer Disease; Dementia; Dietary Supplements; Female; Homocysteine; Humans; Independent Living; Male; Middle Aged; Proportional Hazards Models; Prospective Studies | 2021 |
Direct Quantification and Visualization of Homocysteine, Cysteine, and Glutathione in Alzheimer's and Parkinson's Disease Model Tissues.
Topics: Alzheimer Disease; Animals; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Humans; Mice; Parkinson Disease | 2021 |
Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Diet; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hydroxyurea; Inflammation; Lipoxygenase; Male; Mice, Transgenic; Phenotype; Phosphorylation; Synapses; tau Proteins; Up-Regulation; Vitamin B Complex; Vitamin B Deficiency | 2017 |
Oxidative Stress Markers and Metal Ions are Correlated With Cognitive Function in Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; C-Reactive Protein; Cations; Ceruloplasmin; Copper; Female; Homocysteine; Humans; Iron; Male; Oxidative Stress; Severity of Illness Index; Uric Acid; Zinc | 2017 |
One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond.
Topics: Aged; Alzheimer Disease; Biomarkers; Carbon; Carbon Compounds, Inorganic; Cognition Disorders; Comorbidity; Female; Homocysteine; Humans; Male; Prevalence; Risk Factors; Switzerland | 2017 |
Combined assessment of DYRK1A, BDNF and homocysteine levels as diagnostic marker for Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Animals; Antibodies, Monoclonal; Biomarkers; Brain-Derived Neurotrophic Factor; Dyrk Kinases; Female; Homocysteine; Humans; Male; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; ROC Curve | 2017 |
Plasma Homocysteine and Serum Folate and Vitamin B
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12 | 2017 |
Effects of Homocysteine on white matter diffusion parameters in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Algorithms; Alzheimer Disease; Anisotropy; Brain; Cross-Sectional Studies; Diffusion Tensor Imaging; Female; Homocysteine; Humans; Male; Neuroimaging; White Matter | 2017 |
Homocysteine concentrations in the cognitive progression of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition; Disease Progression; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Mental Status and Dementia Tests; Neuropsychological Tests; Nutrition Assessment; Nutritional Status; Surveys and Questionnaires; Time Factors; Up-Regulation; Vitamin B 12 | 2017 |
Genetic influence of plasma homocysteine on Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Atrophy; Cognitive Dysfunction; Female; Genetic Association Studies; Genetic Predisposition to Disease; Gray Matter; Homocysteine; Humans; Male; Multifactorial Inheritance; Risk Factors; tau Proteins; White People | 2018 |
Low-grade systemic inflammation is associated with functional disability in elderly people affected by dementia.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; C-Reactive Protein; Case-Control Studies; Cognitive Dysfunction; Dementia; Disability Evaluation; Disease Progression; Female; Geriatric Assessment; Homocysteine; Humans; Inflammation; Italy; Male; Reference Values; Retrospective Studies | 2018 |
Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.
Topics: Alzheimer Disease; Animals; Brain; Cell Line, Tumor; Cyclin-Dependent Kinase 5; Disease Models, Animal; Glycogen Synthase Kinase 3; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Transgenic; Neurofibrillary Tangles; Phosphorylation; Protein Aggregation, Pathological; Protein Phosphatase 2; tau Proteins; Tauopathies | 2018 |
Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Cognition Disorders; Disease Models, Animal; Homocysteine; Male; Maze Learning; Moringa oleifera; Nerve Tissue Proteins; Neurons; Oxidative Stress; Peptide Fragments; Phosphorylation; Plant Extracts; Rats; Rats, Sprague-Dawley; Silver Staining; tau Proteins | 2018 |
Elevated levels of brain homocysteine directly modulate the pathological phenotype of a mouse model of tauopathy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Arachidonate 5-Lipoxygenase; Brain; Disease Models, Animal; Female; Homocysteine; Male; Mice; Mice, Transgenic; Phenotype; Phosphorylation; Synapses; tau Proteins; Tauopathies | 2019 |
Interplay between the APOE Genotype and Possible Plasma Biomarkers in Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Biomarkers; Female; Genotype; Homocysteine; Humans; Hydrocortisone; Male; Melatonin; Middle Aged; Prolactin | 2018 |
Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Female; Folic Acid; Glycogen Synthase Kinase 3 beta; Homocysteine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Transgenic; Mutation; Phosphorylation | 2018 |
Association of Induced Hyperhomocysteinemia with Alzheimer's Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury.
Topics: Alzheimer Disease; Animals; Cerebral Cortex; Homocysteine; Hyperhomocysteinemia; Male; Nerve Degeneration; Rats; Rats, Wistar; Reperfusion Injury | 2018 |
Small Vessel Cerebrovascular Pathology Identified by Magnetic Resonance Imaging Is Prevalent in Alzheimer's Disease and Mild Cognitive Impairment: A Potential Target for Intervention.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain Infarction; Cerebrovascular Disorders; Cognitive Dysfunction; Cross-Sectional Studies; Disease Progression; Female; Homocysteine; Humans; Image Processing, Computer-Assisted; Independent Living; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Risk Factors | 2018 |
Folate/Vitamin B Alleviates Hyperhomocysteinemia-Induced Alzheimer-Like Pathologies in Rat Retina.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Dietary Supplements; Disease Models, Animal; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Rats, Sprague-Dawley; Retina; Retinal Vessels; tau Proteins; Vitamin B 12 | 2019 |
Genetic influence of plasma homocysteine on Alzheimer's disease.
Topics: Alzheimer Disease; Cognitive Dysfunction; Genetic Association Studies; Homocysteine; Humans | 2019 |
Methanolic extract of
Topics: Alzheimer Disease; Animals; Homocysteine; Hyperhomocysteinemia; Male; Memory Disorders; Methanol; Neurons; Oxidative Stress; Phosphorus Compounds; Phosphotransferases; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Tamaricaceae; tau Proteins | 2018 |
Associations of lifestyle and vascular risk factors with Alzheimer's brain biomarker changes during middle age: a 3-year longitudinal study in the broader New York City area.
Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Brain; Brain Chemistry; Diet; Glucose; Homocysteine; Humans; Life Style; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; New York City; Positron-Emission Tomography; Prospective Studies; Risk Factors; Vascular Diseases | 2018 |
Maternal choline supplementation ameliorates Alzheimer's disease pathology by reducing brain homocysteine levels across multiple generations.
Topics: Alzheimer Disease; Animals; Brain; Choline; Dietary Supplements; Disease Models, Animal; Female; Homocysteine; Male; Mice; Mice, Transgenic | 2020 |
A validated LC-MS/MS method for the determination of homocysteic acid in biological samples.
Topics: Algorithms; Alzheimer Disease; Body Fluids; Calibration; Chromatography, Liquid; Female; Healthy Volunteers; Homocysteine; Humans; Male; Oxygen; Quality Control; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2019 |
Biomarkers of vascular risk, systemic inflammation, and microvascular pathology and neuropsychiatric symptoms in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biomarkers; C-Reactive Protein; Capillaries; Cerebrovascular Disorders; Cholesterol; Cohort Studies; Cytokines; Data Interpretation, Statistical; Educational Status; Female; Homocysteine; Humans; Inflammation; Male; Neuropsychological Tests; Predictive Value of Tests; Psychiatric Status Rating Scales; Risk Assessment; Sex Characteristics; Texas; Triglycerides | 2013 |
Pro-inflammatory cytokines IL-1β and TNF-α are not associated with plasma homocysteine concentration in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chi-Square Distribution; Female; Homocysteine; Humans; Interleukin-1beta; Logistic Models; Male; Tumor Necrosis Factor-alpha | 2013 |
Impact of homocysteine on cortical perfusion and cognitive decline in mild Alzheimer's dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cerebrovascular Circulation; Cognition Disorders; Disease Progression; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Perfusion; Risk Factors; Tomography, Emission-Computed, Single-Photon | 2013 |
High cortisol and low folate are the only routine blood tests predicting probable Alzheimer's disease after age 75-results of the Vienna Transdanube Aging Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Apolipoprotein E4; Austria; Cohort Studies; Confidence Intervals; Diagnostic Tests, Routine; Female; Folic Acid; Hematologic Tests; Homocysteine; Humans; Hydrocortisone; Longitudinal Studies; Male; Odds Ratio; Prognosis; Risk Factors | 2013 |
Association of methylenetetrahydrofolate reductase polymorphisms with susceptibility to Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Mutation, Missense; Polymorphism, Genetic; Risk Factors | 2013 |
Homocysteine levels and cognitive function scores measured with MMSE and BCAT of middle-aged and elderly subjects in Tianjin City.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; China; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intelligence Tests; Linear Models; Male; Middle Aged; Neuropsychological Tests; Prevalence; Sex Factors; Surveys and Questionnaires | 2013 |
[The clinical studies of hyperhomocysteinemia and Alzheimer's disease].
Topics: Alzheimer Disease; Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 2013 |
Hydroxysafflor yellow A ameliorates homocysteine-induced Alzheimer-like pathologic dysfunction and memory/synaptic disorder.
Topics: Alzheimer Disease; Animals; Blotting, Western; Chalcone; Enzyme-Linked Immunosorbent Assay; Homocysteine; Male; Maze Learning; Memory Disorders; Quinones; Rats; Rats, Sprague-Dawley; Synapses | 2013 |
Alzheimer's disease treated patients showed different patterns for oxidative stress and inflammation markers.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Arginine; Biomarkers; Case-Control Studies; Endothelium, Vascular; Female; Glutathione; Homocysteine; Humans; Inflammation; Interleukin-6; Male; Oxidative Stress; Protein Carbonylation; Tumor Necrosis Factor-alpha | 2013 |
Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study.
Topics: Aged, 80 and over; alpha-Synuclein; Alzheimer Disease; Apolipoproteins E; Cerebral Amyloid Angiopathy; Cerebrovascular Disorders; Community Health Planning; Diagnosis; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neurofibrillary Tangles; Plaque, Amyloid | 2013 |
Serum folate, homocysteine, brain atrophy, and auto-CM system: The Treviso Dementia (TREDEM) study.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Atrophy; Brain; Brain Mapping; Disability Evaluation; Female; Folic Acid; Homocysteine; Humans; Italy; Male; Middle Aged; Neuroimaging; Neuropsychological Tests; Outpatients; Retrospective Studies | 2014 |
The MTHFR 677T allele may influence the severity and biochemical risk factors of Alzheimer's disease in an Egyptian population.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholesterol; Egypt; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12 | 2013 |
Oxidative balance, homocysteine, and uric acid levels in older patients with Late Onset Alzheimer's Disease or Vascular Dementia.
Topics: Advanced Oxidation Protein Products; Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cognitive Dysfunction; Dementia, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Hydrogen Peroxide; Male; Neuropsychological Tests; Oxidative Stress; Retrospective Studies; Tomography, X-Ray Computed; Uric Acid | 2014 |
Impaired renal function and biomarkers of vascular disease in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Biomarkers; Case-Control Studies; Creatinine; Female; Glomerular Filtration Rate; Homocysteine; Humans; Kidney Diseases; Male; Mental Status Schedule; Multivariate Analysis; Risk Factors; Vascular Diseases | 2014 |
Association of homocysteine with hippocampal volume independent of cerebral amyloid and vascular burden.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cognition Disorders; Cognitive Dysfunction; Female; Hippocampus; Homocysteine; Humans; Linear Models; Male; Middle Aged; Risk Factors | 2014 |
The impact of APOE status on relationship of biomarkers of vascular risk and systemic inflammation to neuropsychiatric symptoms in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Biomarkers; Cholesterol; Cytokines; Female; Homocysteine; Humans; Inflammation; Male; Psychiatric Status Rating Scales; Regression, Psychology; Sex Factors; Triglycerides | 2014 |
Plasma homocysteine in Alzheimer's disease with or without co-morbid depressive symptoms.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Comorbidity; Depressive Disorder; Female; Homocysteine; Humans; Male; Middle Aged; Severity of Illness Index | 2014 |
Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cell Line, Tumor; Cognition Disorders; Diet; Disease Models, Animal; Homocysteine; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neuroblastoma; Neurofibrillary Tangles; Plaque, Amyloid; Presenilin-1; Signal Transduction; tau Proteins | 2014 |
Hyperhomocysteinemia is a risk factor for Alzheimer's disease in an Algerian population.
Topics: Aged; Aged, 80 and over; Algeria; Alzheimer Disease; Case-Control Studies; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Risk Factors; Thyrotropin; Uric Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
Correlation between behavioural and psychological symptoms of Alzheimer type dementia and plasma homocysteine concentration.
Topics: Adult; Aged; Alzheimer Disease; Female; Homocysteine; Humans; Male; Middle Aged; Severity of Illness Index | 2014 |
High levels of homocysteine results in cerebral amyloid angiopathy in mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animal Feed; Animals; Brain; Cerebral Amyloid Angiopathy; Diet; Disease Models, Animal; Female; Homocysteine; Hyperhomocysteinemia; Male; Mice, Transgenic; Random Allocation | 2015 |
Fatty acid status and its relationship to cognitive decline and homocysteine levels in the elderly.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cognition; Cognition Disorders; Dementia; Diet; Docosahexaenoic Acids; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Geriatric Assessment; Homocysteine; Humans; Lipids; Male; Memory; Nutritional Status; Risk Factors | 2014 |
There are no differences in IL-6, CRP and homocystein concentrations between women whose mothers had AD and women whose mothers did not have AD.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Brain; C-Reactive Protein; Cross-Sectional Studies; Female; Homocysteine; Humans; Interleukin-6; Middle Aged; Mothers | 2014 |
Fatty acids rehabilitated long-term neurodegenerative: like symptoms in olfactory bulbectomized rats.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Body Temperature Regulation; Brain; Cholesterol; Cytokines; Disease Models, Animal; Eating; Fatty Acids; Homocysteine; Iron; Male; Maze Learning; Motor Activity; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Olfactory Bulb; Rats, Long-Evans; Synaptosomes | 2015 |
The relationship between cholesterol and cognitive function is homocysteine-dependent.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; China; Cholesterol; Cross-Sectional Studies; Dementia; Female; Homocysteine; Humans; Hypercholesterolemia; Lipoproteins, HDL; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Psychometrics; Risk Factors; Statistics as Topic; Triglycerides | 2014 |
Higher homocysteine associated with thinner cortical gray matter in 803 participants from the Alzheimer's Disease Neuroimaging Initiative.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atrophy; Biomarkers; Female; Folic Acid; Gray Matter; Homocysteine; Humans; Life Style; Magnetic Resonance Imaging; Male; Neuroimaging; Risk Factors; Vitamin B Complex | 2015 |
Association between intake of B vitamins and cognitive function in elderly Koreans with cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Republic of Korea; Vitamin B 12; Vitamin B Complex | 2014 |
Associations between Alzheimer's disease and blood homocysteine, vitamin B12, and folate: a case-control study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Chromatography, High Pressure Liquid; Cognition Disorders; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Psychiatric Status Rating Scales; Retrospective Studies; Surveys and Questionnaires; Vitamin B 12 | 2015 |
Plasma thiols levels in Alzheimer's disease mice under diet-induced hyperhomocysteinemia: effect of S-adenosylmethionine and superoxide-dismutase supplementation.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Chromatography; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; S-Adenosylmethionine; Sulfhydryl Compounds; Superoxide Dismutase | 2015 |
Apolipoprotein E genotype modulates effects of vitamin B12 and homocysteine on grey matter volume in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Case-Control Studies; Female; Genotype; Gray Matter; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Republic of Korea; Vitamin B 12 | 2016 |
Hydrogen Sulfide Ameliorates Homocysteine-Induced Alzheimer's Disease-Like Pathology, Blood-Brain Barrier Disruption, and Synaptic Disorder.
Topics: Alzheimer Disease; Animals; Antigens, CD; Avoidance Learning; Blood-Brain Barrier; Cadherins; Cerebrovascular Circulation; Claudin-5; Cystathionine beta-Synthase; Dizocilpine Maleate; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Homocysteine; Hydrogen Sulfide; Intercellular Adhesion Molecule-1; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Memory; Mice, Inbred C57BL; Microtubule-Associated Proteins; Microvessels; Nerve Tissue Proteins; Permeability; RNA, Messenger; Synapses | 2016 |
Methylation analysis of multiple genes in blood DNA of Alzheimer's disease and healthy individuals.
Topics: 5' Untranslated Regions; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid Precursor Protein Secretases; Apolipoprotein E4; Aspartic Acid Endopeptidases; Biomarkers; Case-Control Studies; CpG Islands; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Presenilin-1; Promoter Regions, Genetic; Sex Factors; Vitamin B 12 | 2015 |
Increased levels of plasma amyloid-beta are related to cortical thinning and cognitive decline in cognitively normal elderly subjects.
Topics: Aged; Aging; Alzheimer Disease; Amyloid beta-Peptides; Cerebral Cortex; Cognition; Cognition Disorders; Female; Homocysteine; Humans; Male; Peptide Fragments; Risk Factors | 2015 |
Buccal Cytome Biomarkers and Their Association with Plasma Folate, Vitamin B12 and Homocysteine in Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Biomarkers; Cheek; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2015 |
Effects of an antioxidant beverage on biomarkers of oxidative stress in Alzheimer's patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Aged, 80 and over; Alanine Transaminase; Alzheimer Disease; Antioxidants; Aspartate Aminotransferases; Beverages; Biomarkers; Body Mass Index; C-Reactive Protein; Case-Control Studies; Deoxyguanosine; Female; Ferritins; Folic Acid; Glutathione Peroxidase; Homocysteine; Humans; Isoprostanes; Lipids; Male; Malus; Oxidative Stress; Plant Extracts; Protein Carbonylation; Superoxide Dismutase; Tea; Vitamin B 12 | 2016 |
Homocysteine, antioxidant vitamins and lipids as biomarkers of neurodegeneration in Alzheimer's disease versus non-Alzheimer's dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Biomarkers; Cognition Disorders; Dementia; Female; Homocysteine; Humans; Lipids; Male; Middle Aged; Vitamins | 2016 |
Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study.
Topics: Aged; Alzheimer Disease; Amino Acids, Sulfur; Atrophy; Brain; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Risk Factors; Statistics as Topic; Sweden; Vitamin B 12; White Matter | 2016 |
A multipronged, nutritional-based strategy for managing Alzheimer's disease.
Topics: Aged; Albumins; Aluminum; Alzheimer Disease; Amyloid beta-Peptides; Animals; Atrophy; Blood-Brain Barrier; Brain; Carbohydrate Metabolism; Diabetes Mellitus; Dietary Supplements; Gray Matter; Homocysteine; Humans; Learning; Magnesium; Magnesium Deficiency; Memory; Middle Aged; Models, Theoretical; N-Methylaspartate; Nutritional Sciences; Plasma Exchange; Rats; Silicic Acid; Vitamin B Complex | 2016 |
Conversion from MCI to AD in patients with the APOE ε4 genotype: Prediction by plasma HCY and serum BDNF.
Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Biomarkers; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Disease Progression; Female; Genotype; Homocysteine; Humans; Male; Sensitivity and Specificity | 2016 |
The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration.
Topics: Aged; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2) | 2016 |
Artificial Neural Networks Link One-Carbon Metabolism to Gene-Promoter Methylation in Alzheimer's Disease.
Topics: Age Factors; Aged; Alzheimer Disease; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Biomarkers; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neural Networks, Computer; Presenilin-1; Promoter Regions, Genetic; Sex Factors; Vitamin B 12 | 2016 |
The involvement of homocysteine in stress-induced Aβ precursor protein misprocessing and related cognitive decline in rats.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Hippocampus; Homocysteine; Male; Protein Processing, Post-Translational; Rats, Sprague-Dawley; Stress, Psychological | 2016 |
Targeting therapy for homocysteic acid in the blood represents a potential recovery treatment for cognition in Alzheimer's disease patients.
Topics: Alzheimer Disease; Animals; Antibodies; Cognition Disorders; Disease Models, Animal; Homocysteine; Mice | 2016 |
Testing for homocysteine in clinical practice.
Topics: Alzheimer Disease; Blood Chemical Analysis; Cardiovascular Diseases; Cognition Disorders; Delivery of Health Care; Homocysteine; Humans; Hyperhomocysteinemia; Practice Patterns, Physicians' | 2017 |
Clinical and Environmental Correlates of Serum BDNF: A Descriptive Study with Plausible Implications for AD Research.
Topics: Adult; Alzheimer Disease; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Cohort Studies; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Linear Models; Male; Middle Aged; Psychiatric Status Rating Scales; Tumor Necrosis Factor-alpha | 2017 |
Malondialdehyde, carbonyl proteins and albumin-disulphide as useful oxidative markers in mild cognitive impairment and Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biomarkers; Case-Control Studies; Cognition Disorders; Disulfides; Female; Folic Acid; Homocysteine; Humans; Male; Malondialdehyde; Middle Aged; Neopterin; Nerve Degeneration; Oxidative Stress; Protein Carbonylation; Serum Albumin; Severity of Illness Index; Vitamin B 12 | 2008 |
Folate deprivation, the methionine cycle, and Alzheimer's disease.
Topics: Alzheimer Disease; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Methionine | 2008 |
C-reactive protein: vascular risk marker in elderly patients with mental illness.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; C-Reactive Protein; Cerebrovascular Disorders; Cognition Disorders; Cystatin C; Depression; Female; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Risk Factors | 2008 |
B vitamins for prevention of cognitive decline: insufficient evidence to justify treatment.
Topics: Alzheimer Disease; Cognition; Cognition Disorders; Dietary Supplements; Homocysteine; Humans; Vitamin B Complex | 2008 |
Cognitive performance and plasma levels of homocysteine, vitamin B12, folate and lipids in patients with Alzheimer disease.
Topics: Aged; Alzheimer Disease; Cholesterol, HDL; Cholesterol, LDL; Cognition; Cross-Sectional Studies; Databases, Factual; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Psychomotor Performance; Sex Characteristics; Triglycerides; Vitamin B 12 | 2008 |
Higher folate intake is related to lower risk of Alzheimer's disease in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Male; Nutrition Assessment; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
[Plasma levels of endogenous hydrogen sulfide and homocysteine in patients with Alzheimer's disease and vascular dementia and the significance thereof].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Female; Homocysteine; Humans; Hydrogen Sulfide; Male; Middle Aged; Psychiatric Status Rating Scales | 2008 |
Association between genetic and environmental factors and the risk of Alzheimer's disease.
Topics: Alzheimer Disease; Apolipoproteins E; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hypercholesterolemia; Methylenetetrahydrofolate Reductase (NADPH2); Nitric Oxide Synthase Type III; Risk Factors; Vitamin B 12 | 2008 |
Brain MRI, apoliprotein E genotype, and plasma homocysteine in American Indian Alzheimer disease patients and Indian controls.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Brain; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Indians, North American; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Polymorphism, Genetic | 2009 |
Serum homocysteine: interplay with other circulating and genetic factors in association to Alzheimer's type dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; C-Reactive Protein; Case-Control Studies; Estradiol; Female; Homocysteine; Humans; Male; Middle Aged; Mutation; Polymorphism, Restriction Fragment Length; Testosterone; Tetrahydrofolates; Urea; Uric Acid | 2009 |
Interaction between interleukin-8 and methylenetetrahydrofolate reductase genes modulates Alzheimer's disease risk.
Topics: Aged; Alleles; Alzheimer Disease; China; Female; Gene Frequency; Genotype; Homocysteine; Humans; Interleukin-8; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment | 2009 |
Paraoxonase activity and dementia.
Topics: Aged; Alzheimer Disease; Aryldialkylphosphatase; Cholesterol; Cholesterol, HDL; Cognition Disorders; Dementia; Dementia, Vascular; Female; Homocysteine; Humans; Immunoenzyme Techniques; Male; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Sequence Analysis, DNA; Spectrophotometry; Triglycerides | 2009 |
Cerebral white matter lesions in patients with dementia - from MCI to severe Alzheimer's disease.
Topics: Aged; Aging; Alzheimer Disease; Brain; Cognition Disorders; Disease Progression; Female; Homocysteine; Humans; Hypertension; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated | 2009 |
High-dose B vitamin supplements and Alzheimer disease.
Topics: Alzheimer Disease; Cognition Disorders; Dietary Supplements; Homocysteine; Humans; Reference Values; Vitamin B Complex | 2009 |
High-dose B vitamin supplements and Alzheimer disease.
Topics: Alzheimer Disease; Blood-Brain Barrier; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Vitamin B Complex | 2009 |
Homocysteine and holo-transcobalamin and the risk of dementia and Alzheimers disease: a prospective study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Community Health Planning; Dementia; Female; Homocysteine; Humans; Male; Models, Anatomic; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Transcobalamins | 2009 |
Homocysteine as a predictor of cognitive decline in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Cohort Studies; Female; Homocysteine; Humans; Longitudinal Studies; Male; Neuropsychological Tests; Nonlinear Dynamics; Predictive Value of Tests | 2010 |
Relationship between genetic polymorphism, serum folate and homocysteine in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide | 2008 |
Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; Case-Control Studies; Female; Genotype; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Neuropsychological Tests; Peptide Fragments; S-Adenosylmethionine; tau Proteins; Tetrahydrofolates; Young Adult | 2009 |
[Does acidosis in brain play a role in Alzheimer's disease?].
Topics: Acidosis; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Brain; Brain Ischemia; Cell Death; Cerebral Arteries; Cholesterol; Homocysteine; Humans; Inflammation; Lactic Acid; Neurons; Risk Factors; tau Proteins | 2009 |
Sialic acid, homocysteine and CRP: potential markers for dementia.
Topics: Aged; Alzheimer Disease; Biomarkers; C-Reactive Protein; Dementia; Female; Homocysteine; Humans; Male; N-Acetylneuraminic Acid; Reproducibility of Results; Sensitivity and Specificity | 2009 |
A prospective study on the development of Alzheimer's disease with regard to thyroid-stimulating hormone and homocysteine.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Cohort Studies; Creatinine; Disease Progression; Female; Homocysteine; Humans; Male; Neuropsychological Tests; Prospective Studies; Risk Assessment; Socioeconomic Factors; Sweden; Thyrotropin | 2009 |
Elevated serum homocysteine level is not associated with serum C-reactive protein in patients with probable Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Blood Pressure; Body Mass Index; C-Reactive Protein; Cognition Disorders; Female; Homocysteine; Humans; Male; Neuropsychological Tests; Sex Factors | 2009 |
Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Brain; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Down-Regulation; Female; Food, Formulated; Glycogen Synthase Kinase 3; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Transgenic; Plaque, Amyloid; Serine | 2010 |
Homocysteine may contribute to pathogenesis of RNA damage in brains with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Brain; Case-Control Studies; Female; Guanosine; Homocysteine; Humans; Male; Middle Aged; RNA; Statistics as Topic | 2009 |
Homocystamides promote free-radical and oxidative damage to proteins.
Topics: Alzheimer Disease; Cardiovascular Diseases; Congenital Abnormalities; Free Radicals; Homocysteine; Humans; Hydrogen Bonding; Kinetics; Lysine; Osteoporosis; Oxidative Stress; Protein Processing, Post-Translational; Renal Insufficiency; Serum Albumin | 2010 |
Treatment of Alzheimer's disease with anti-homocysteic acid antibody in 3xTg-AD male mice.
Topics: Alzheimer Disease; Animals; Antibodies; Homocysteine; Immunohistochemistry; Immunotherapy; Male; Maze Learning; Mice; Mice, Transgenic | 2010 |
Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons.
Topics: Alzheimer Disease; Animals; Apoptosis; Caspase 3; Cerebral Cortex; DNA Fragmentation; Drugs, Chinese Herbal; Homocysteine; Hydro-Lyases; Neurons; Neuroprotective Agents; Phosphorylation; Phytotherapy; Rats; Rats, Sprague-Dawley; tau Proteins | 2010 |
Oxidative LDL modification is increased in vascular dementia and is inversely associated with cognitive performance.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Cognition Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Oxidation-Reduction | 2010 |
Protective effect of isoflavones against homocysteine-mediated neuronal degeneration in SH-SY5Y cells.
Topics: Alzheimer Disease; Apoptosis; Cell Line, Tumor; Endoplasmic Reticulum; Homocysteine; Humans; Isoflavones; Nerve Degeneration; Neurons; Protective Agents; S-Adenosylhomocysteine | 2010 |
Fasting and post-methionine homocysteine levels in Alzheimers disease and vascular dementia.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cohort Studies; Dementia, Vascular; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Statistics, Nonparametric; Vitamin B 12 | 2009 |
Increased tissue factor pathway inhibitor and homocysteine in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biomarkers; Female; Homocysteine; Humans; Lipoproteins; Male; Reproducibility of Results; Sensitivity and Specificity | 2012 |
S-adenosylhomocysteine: a better marker of the development of Alzheimer's disease than homocysteine?
Topics: Alzheimer Disease; Animals; Biomarkers; Homocysteine; Humans; S-Adenosylhomocysteine | 2010 |
Impacts of hyper-homocysteinemia and white matter hyper-intensity in Alzheimer's disease patients with normal creatinine: an MRI-based study with longitudinal follow-up.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Blood Glucose; Brain; Cholesterol; Cross-Sectional Studies; Fasting; Female; Homocysteine; Humans; Logistic Models; Longitudinal Studies; Magnetic Resonance Imaging; Male; Mental Status Schedule; Nerve Fibers, Myelinated; Neuropsychological Tests | 2010 |
S-adenosylmethionine is decreased in the cerebrospinal fluid of patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Apolipoprotein E4; Chi-Square Distribution; Cross-Sectional Studies; Fasting; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Mental Status Schedule; Middle Aged; S-Adenosylmethionine; White People | 2010 |
Aging and antioxidants modulate rat brain levels of homocysteine and dehydroepiandrosterone sulphate (DHEA-S): implications in the pathogenesis of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Animals; Antioxidants; Brain; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Homocysteine; Rats; Rats, Wistar | 2010 |
Plasma homocysteine levels and major depressive disorders in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Depressive Disorder, Major; Female; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Severity of Illness Index | 2010 |
The relationship of cardiovascular risk factors to Alzheimer disease in Choctaw Indians.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Cardiovascular Diseases; Case-Control Studies; Diabetes Mellitus; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hypertension; Indians, North American; Male; Middle Aged; Oklahoma; Risk Factors; Statistics, Nonparametric; White People | 2011 |
Hyperhomocysteinemia in Alzheimer dementia patients and cognitive decline after 6 months follow-up period.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cognition Disorders; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Retrospective Studies | 2010 |
Depression, Parkinson disease, Alzheimer disease. The homocysteine hypothesis.
Topics: Alzheimer Disease; Depression; Homocysteine; Humans; Parkinson Disease | 2010 |
Homocysteine, another risk factor for Alzheimer disease, impairs apolipoprotein E3 function.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apolipoprotein E3; Apolipoprotein E4; Brain; Disulfides; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Mice; Mice, Knockout; Protein Multimerization; Risk Factors | 2010 |
Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal study.
Topics: Aged; Aging; Alzheimer Disease; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Dementia; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Mental Status Schedule; Odds Ratio; Risk Factors; Transcobalamins | 2010 |
Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation.
Topics: Aged; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neopterin; Oxidative Stress; Protein Carbonylation; Reference Values; Tryptophan; Vitamin B 12 | 2010 |
Modulatory effects of vitamin E, acetyl-L-carnitine and α-lipoic acid on new potential biomarkers for Alzheimer's disease in rat model.
Topics: Alzheimer Disease; Animals; Antioxidants; Biomarkers; Brain; Carnitine; Cholinesterase Inhibitors; Dietary Supplements; Disease Models, Animal; Donepezil; Enzyme-Linked Immunosorbent Assay; Homocysteine; Indans; Insulin-Like Growth Factor I; Interleukin-1beta; Male; Piperidines; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tumor Necrosis Factor-alpha; Vitamin E | 2012 |
Alzheimer disease: homocysteine and alzheimer disease: an intervention study.
Topics: Alzheimer Disease; Homocysteine; Humans; Randomized Controlled Trials as Topic; Vitamin B Complex | 2011 |
Folate and homocysteine in the cerebrospinal fluid of patients with Alzheimer's disease or dementia: a case control study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Dementia; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Retrospective Studies; Statistics, Nonparametric; Tunisia | 2011 |
Homocysteine effects on brain volumes mapped in 732 elderly individuals.
Topics: Aged; Alzheimer Disease; Brain; Brain Mapping; Cognition Disorders; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male | 2011 |
Biomarkers for cognitive decline: opportunities and challenges.
Topics: Aged; Alzheimer Disease; Biomarkers; Dementia; Homocysteine; Humans | 2011 |
Homocysteine in Alzheimer's disease: role of dietary folate, vitamin B6 and B12.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Diet; Diet Records; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6 | 2011 |
Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; Australia; Brain; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Vitamin B 12 | 2011 |
Acetyl-L-carnitine attenuates homocysteine-induced Alzheimer-like histopathological and behavioral abnormalities.
Topics: Acetylcarnitine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Brain; Disease Models, Animal; Hippocampus; Homocysteine; Male; Maze Learning; Phosphorylation; Rats; Rats, Sprague-Dawley; Silver Staining; tau Proteins | 2011 |
Folate, homocysteine, vitamin B12, and polymorphisms of genes participating in one-carbon metabolism in late-onset Alzheimer's disease patients and healthy controls.
Topics: Age of Onset; Aged; Alleles; Alzheimer Disease; Biomarkers; Case-Control Studies; Female; Folic Acid; Genotype; Health; Homocysteine; Humans; Male; Polymorphism, Genetic; Vitamin B 12 | 2012 |
Plasma homocysteine level and apathy in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apathy; Female; Homocysteine; Humans; Male; Sex Factors | 2011 |
Cognitive reserve, homocysteine, and cognition in the Bavarian School Sisters Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Educational Status; Female; Homocysteine; Humans | 2011 |
Effect of N-homocysteinylation on physicochemical and cytotoxic properties of amyloid β-peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Chemical Phenomena; Cytotoxins; Homocysteine; Humans; Hyperhomocysteinemia; PC12 Cells; Protein Multimerization; Protein Processing, Post-Translational; Rats; Structure-Activity Relationship | 2012 |
Metabolism and neurotoxicity of homocysteine thiolactone in mice: evidence for a protective role of paraoxonase 1.
Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Brain; Epilepsy; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kidney; Liver; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Degeneration; Spleen | 2012 |
Predicting missing biomarker data in a longitudinal study of Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognitive Dysfunction; Cohort Studies; Dementia, Vascular; Fluorodeoxyglucose F18; Homocysteine; Humans; Logistic Models; Longitudinal Studies; Magnetic Resonance Imaging; Neuropsychological Tests; Patient Dropouts; Peptide Fragments; Positron-Emission Tomography; Research Design; Risk Factors; tau Proteins | 2012 |
Urinary homocysteic acid levels correlate with mini-mental state examination scores in Alzheimer's disease patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Electrochemistry; Female; Homocysteine; Humans; Male; Mental Status Schedule; Middle Aged; Smoking; Statistics as Topic | 2012 |
Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Biomarkers; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylmethionine; Young Adult | 2012 |
Elevated plasma homocysteine level is not primarily related to Alzheimer's disease.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Relationship of cognitive function with B vitamin status, homocysteine, and tissue factor pathway inhibitor in cognitively impaired elderly: a cross-sectional survey.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Mental Status Schedule; Neuropsychological Tests; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Altered levels of homocysteine and serum natural antioxidants links oxidative damage to Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Neuropsychological Tests; Oxidative Stress | 2013 |
Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.
Topics: Alzheimer Disease; Animals; Betaine; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Male; Memory Disorders; Rats; Rats, Sprague-Dawley | 2013 |
Association between plasma biomarkers, CDK5 polymorphism and the risk of Alzheimer's disease.
Topics: Alzheimer Disease; Apolipoproteins E; Cyclin-Dependent Kinase 5; Female; Folic Acid; Genetic Association Studies; Genotype; Homocysteine; Humans; Lipids; Male; Meta-Analysis as Topic; Middle Aged; Polymorphism, Genetic; Riboflavin | 2012 |
Optimal use of markers for cobalamin and folate status in a psychogeriatric population.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 2002 |
Homocysteine, stroke, and dementia.
Topics: Aging; Alzheimer Disease; Causality; Comorbidity; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Vitamin B Complex | 2002 |
Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland.
Topics: Aged; Alleles; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Comorbidity; Dementia, Vascular; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Northern Ireland; Nutritional Status; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Risk Assessment; Risk Factors; Statistical Distributions; Stroke | 2002 |
Homocysteine, vitamin B6, and vascular disease in patients with AD.
Topics: Aged; Alzheimer Disease; Female; Homocysteine; Humans; Male; Vascular Diseases; Vitamin B 6 | 2002 |
Differential relations between cognition and 15N isotopic content of hair in elderly people with dementia and controls.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Animals; Case-Control Studies; Chi-Square Distribution; Diet; Diet Records; Diet, Vegetarian; Female; Fishes; Hair; Homocysteine; Humans; Male; Middle Aged; Nitrogen Isotopes; Regression Analysis | 2002 |
Homocysteine and brain atrophy on MRI of non-demented elderly.
Topics: Aged; Alzheimer Disease; Amygdala; Analysis of Variance; Biomarkers; Brain; Cross-Sectional Studies; Female; Hippocampus; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged | 2003 |
Folate delivers head-to-toe health advantages. The B vitamin that benefits unborn babies may also protect the hearts and minds (and colons) of adults.
Topics: Alzheimer Disease; Anencephaly; Colonic Neoplasms; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Male; Pregnancy; Spinal Dysraphism; Stroke | 2002 |
Feeding the aging brain.
Topics: Aging; Alzheimer Disease; Antioxidants; Brain; Cholesterol; Diet; Dietary Fats; Exercise; Fish Oils; Homocysteine; Humans; Hypertension; United States | 2003 |
Alzheimer's disease and total plasma aminothiols.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Cysteine; Folic Acid; Glutathione; Homocysteine; Humans; Mental Status Schedule; Neuropsychological Tests; Prognosis; Reference Values; Vitamin B 12 | 2003 |
Will caloric restriction and folate protect against AD and PD?
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Animals; Brain; Brain-Derived Neurotrophic Factor; Caloric Restriction; Disease Models, Animal; Energy Intake; Folic Acid; Homocysteine; Humans; Middle Aged; Neurons; Oxidative Stress; Parkinson Disease; Rats; Risk Factors | 2003 |
Diet and Alzheimer's disease.
Topics: Alzheimer Disease; Anticholesteremic Agents; Antioxidants; Brain; Cholesterol, HDL; Cholesterol, LDL; Fatty Acids, Omega-3; Homocysteine; Humans; Hypercholesterolemia | 2003 |
[Serum markers in relation to cognitive functioning in an aging population: results of the Maastricht Aging Study (MAAS)].
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Biomarkers; C-Reactive Protein; Cholesterol; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Haptoglobins; Homocysteine; Humans; Lanosterol; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Psychomotor Performance | 2003 |
Homocysteine and folate deficiency sensitize oligodendrocytes to the cell death-promoting effects of a presenilin-1 mutation and amyloid beta-peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cell Death; Cells, Cultured; Disease Models, Animal; DNA Damage; Enzyme Inhibitors; Folic Acid Deficiency; Homocysteine; Membrane Proteins; Mice; Mice, Mutant Strains; Mutation; Nerve Fibers, Myelinated; Oligodendroglia; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Presenilin-1; Tumor Suppressor Protein p53; Up-Regulation | 2003 |
Plasma total homocysteine levels, dietary vitamin B6 and folate intake in AD and healthy aging.
Topics: Adult; Aging; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Cholesterol; Educational Status; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Serum Albumin; Smoking; Triglycerides; Vitamin B 6 | 2003 |
Homocysteine, apolipoproteine E and methylenetetrahydrofolate reductase in Alzheimer's disease and mild cognitive impairment.
Topics: Aged; Alzheimer Disease; Apolipoproteins E; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12 | 2003 |
Homocysteine and the brain: vascular risk factor or neurotoxin?
Topics: Aged; Alzheimer Disease; Brain; Case-Control Studies; Clinical Trials as Topic; Dementia, Vascular; Homocysteine; Humans; Neurotoxins; Risk Factors; Vascular Diseases | 2003 |
Memantine in moderate-to-severe Alzheimer's disease.
Topics: Alzheimer Disease; Excitatory Amino Acid Antagonists; Homocysteine; Humans; Hyperhomocysteinemia; Memantine; N-Methylaspartate | 2003 |
Homocysteine and methylenetetrahydrofolate reductase polymorphism in Alzheimer's disease.
Topics: Age Factors; Aged; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Case-Control Studies; Confidence Intervals; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Polymorphism, Genetic; Pteroylpolyglutamic Acids; Regression Analysis; Statistics, Nonparametric; Transcobalamins; Vitamin B 12 | 2004 |
CT brain findings in clinical dementia investigation--underestimation of mixed dementia.
Topics: Aged; Alzheimer Disease; Atrophy; Basal Ganglia; Cerebral Infarction; Dementia; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Male; Temporal Lobe; Tomography, X-Ray Computed | 2004 |
A haplotype of the methylenetetrahydrofolate reductase gene is protective against late-onset Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Brain; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Haplotypes; Homocysteine; Humans; Immunity, Innate; Japan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic | 2004 |
Homocysteine and Alzheimer's disease: a modifiable risk?
Topics: Alzheimer Disease; Brain; Cystathionine beta-Synthase; Homocysteine; Humans; Risk Factors | 2004 |
Cerebrospinal fluid tau protein and periventricular white matter lesions in patients with mild cognitive impairment: implications for 2 major pathways.
Topics: Aged; Alzheimer Disease; Apolipoproteins E; Biomarkers; Brain; Cognition Disorders; Dementia; Disease Progression; Female; Follow-Up Studies; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Prospective Studies; Radiography; Risk Factors; tau Proteins | 2004 |
Low thyroid-stimulating hormone as an independent risk factor for Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Comorbidity; Creatinine; Diabetes Mellitus; England; Female; Follow-Up Studies; Homocysteine; Humans; Hypertension; Male; Odds Ratio; Reference Values; Risk Factors; Serum Albumin; Smoking; Thyrotropin; Thyroxine | 2004 |
Plasma homocysteine levels and risk of Alzheimer disease.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Comorbidity; Confounding Factors, Epidemiologic; Cross-Sectional Studies; Cysteine; Dementia; Diabetes Mellitus; Ethnicity; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Neuropsychological Tests; New York City; Prevalence; Risk Factors; Sampling Studies; Stroke; Vitamin B 12; Vitamin B 6 | 2004 |
Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons.
Topics: Alzheimer Disease; Amidohydrolases; Animals; Antioxidants; Arginine; Brain; Cells, Cultured; Cognition Disorders; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Feedback, Physiological; Homocysteine; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Proline; Rats; Thiocarbamates; Up-Regulation | 2004 |
Association of IL-1 RN*2 allele and methionine synthase 2756 AA genotype with dementia severity of sporadic Alzheimer's disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alleles; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Female; Genotype; Homocysteine; Humans; Interleukin-1; Italy; Male; Middle Aged; Polymorphism, Genetic; Severity of Illness Index | 2004 |
Homocysteine, Alzheimer genes and proteins, and measures of cognition and depression in older men.
Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Depression; Gene Expression; Homocysteine; Humans; Male; Neuropsychological Tests; Point Mutation; Polymerase Chain Reaction; Severity of Illness Index; Surveys and Questionnaires; Tetrahydrofolates | 2004 |
Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia.
Topics: 17-alpha-Hydroxypregnenolone; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dementia, Vascular; Dipeptides; Female; Glutathione; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Predictive Value of Tests; Pregnenolone; Radioimmunoassay; Sensitivity and Specificity; Sex Factors; Statistics, Nonparametric; Sulfhydryl Compounds | 2004 |
Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cognition Disorders; Cross-Sectional Studies; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Risk Factors; Switzerland; Vitamin B 12 | 2004 |
Plasma homocysteine concentration relates to the severity but not to the duration of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Disease Progression; Female; Homocysteine; Humans; Male; Regression Analysis; Statistics, Nonparametric; Time Factors | 2004 |
Increased homocysteine and decreased adenosine formation in Alzheimer's disease.
Topics: Adenosine; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cerebrovascular Disorders; Down-Regulation; Female; Homocysteine; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Neuroprotective Agents; Predictive Value of Tests; S-Adenosylhomocysteine; Up-Regulation | 2004 |
Lack of genetic dispositions to hyperhomocysteinemia in Alzheimer disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Age Factors; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Chi-Square Distribution; Cystathionine beta-Synthase; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Genetic; Sex Factors; Survival Analysis | 2004 |
Homocysteine, vitamin B12 and folate in vascular dementia and in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Case-Control Studies; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neurons; Nutritional Status; Oxidative Stress; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Studies on homocysteine and dehydroepiandrosterone sulphate plasma levels in Alzheimer's disease patients and in Parkinson's disease patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dehydroepiandrosterone Sulfate; Female; Homocysteine; Humans; Male; Middle Aged; Parkinson Disease | 2004 |
Plasma homocysteine, vitamin B12 and folate in Alzheimer's patients and healthy Arabs in Israel.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arabs; Case-Control Studies; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Israel; Male; Odds Ratio; Vitamin B 12 | 2004 |
Studies on homocysteine plasma levels in Alzheimer's patients. Relevance for neurodegeneration.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Female; Homocysteine; Humans; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2005 |
S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Brain; Cell Line, Tumor; Culture Media, Serum-Free; DNA Methylation; Endopeptidases; Folic Acid Deficiency; Gene Expression; Homocysteine; Humans; Membrane Proteins; Presenilin-1; Promoter Regions, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2005 |
Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Cholesterol; Dementia, Vascular; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germany; Glutathione Transferase; Homocysteine; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Point Mutation; Polymorphism, Genetic; Stroke | 2004 |
Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
Topics: Aged; Aging; Alzheimer Disease; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Longitudinal Studies; Male; Risk Factors; Vitamin B 12; Vitamin B 6 | 2005 |
Plasma homocysteine concentration and its relation to symptoms of vascular disease in psychogeriatric patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Protein S; Vascular Diseases; Vitamin B 12 | 2005 |
Homocysteine and related genetic polymorphisms in Down's syndrome IQ.
Topics: Alleles; Alzheimer Disease; Apolipoproteins E; Diagnostic and Statistical Manual of Mental Disorders; Down Syndrome; Folic Acid; Homocysteine; Humans; Intelligence; Karyotyping; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Transcobalamins; Vitamin B 12 | 2005 |
Homocysteic acid induces intraneuronal accumulation of neurotoxic Abeta42: implications for the pathogenesis of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; CHO Cells; Cricetinae; Cricetulus; Endopeptidases; Enzyme Inhibitors; Homocysteine; Humans; Inclusion Bodies; Neurons; Peptide Fragments; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2005 |
Homocysteine, vitamin B 12 and folate in Alzheimer's and vascular dementias: the paradoxical effect of the superimposed type II diabetes mellitus condition.
Topics: Aged; Alzheimer Disease; Analysis of Variance; Dementia, Vascular; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2005 |
Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease.
Topics: Aged; Alzheimer Disease; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Male; Middle Aged; Parkinson Disease | 2005 |
Homocysteine and cognitive function in institutionalised elderly A cross-sectional analysis.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition; Cross-Sectional Studies; Female; Geriatric Assessment; Homes for the Aged; Homocysteine; Humans; Linear Models; Male; Psychiatric Status Rating Scales | 2006 |
Subjective memory complaints with and without objective memory impairment: relationship with risk factors for dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Anxiety; Apolipoprotein E4; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Risk Factors; Self-Assessment; Sick Role; Western Australia | 2005 |
The relation between homocysteine levels and development of Alzheimer's disease in mild cognitive impairment patients.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Creatinine; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Sex Characteristics; Thyrotropin; Vitamin B 12; Vitamins | 2005 |
Homocysteine and folate as risk factors for dementia and Alzheimer disease.
Topics: Aged; Aging; Alzheimer Disease; Cognition; Cohort Studies; Cross-Sectional Studies; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Italy; Male; Prospective Studies; Risk Factors; Seroepidemiologic Studies | 2005 |
Cell cycle-related protein expression in Alzheimer's disease and vascular disease.
Topics: Aged; Alzheimer Disease; Apolipoproteins E; Apoptosis; Cerebrovascular Disorders; Homocysteine; Humans | 2003 |
Plasma homocysteine levels are not increased in murine models of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Biomarkers; Disease Models, Animal; Homocysteine; Humans; Mice; Mice, Transgenic; Risk Factors | 2005 |
Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimer's disease.
Topics: Adult; Aged; Alzheimer Disease; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged | 2005 |
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12 | 2005 |
Homocysteine and cognition--no longer a hypothesis?
Topics: Aged; Alzheimer Disease; Cognition; Cognition Disorders; Homocysteine; Humans; Methionine; Models, Biological; Models, Theoretical; Neurodegenerative Diseases; Vitamin B 12; Vitamins | 2006 |
A cross-sectional study of homocysteine-, NO-levels, and CT-findings in Alzheimer dementia, vascular dementia and controls.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Cross-Sectional Studies; Dementia, Vascular; Homocysteine; Humans; Nitric Oxide; Tomography, X-Ray Computed | 2005 |
Plasma homocysteine and vascular disease in psychogeriatric patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Confusion; Dementia; Dementia, Vascular; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Middle Aged; Natriuretic Peptide, Brain; Neuropsychological Tests; Peptide Fragments; Reference Values; Risk Factors; Vitamin B 12 | 2006 |
Relationship of homocysteine and gene polymorphisms of its related metabolic enzymes with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cystathionine beta-Synthase; Female; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length | 2005 |
Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta peptide levels.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Animals; Blotting, Western; Brain; Brain Chemistry; Cell Count; Cystathionine beta-Synthase; Disease Models, Animal; Female; Homocysteine; Immunohistochemistry; Male; Mice; Mice, Transgenic; Mutation; Neurons; Polymerase Chain Reaction; Sex Factors | 2006 |
Relation between vascular risk factors and cognition at age 75.
Topics: Aged; Aging; Alzheimer Disease; Austria; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Cognition Disorders; Cohort Studies; Comorbidity; Cross-Sectional Studies; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperlipidemias; Hypertension; Lipoproteins; Male; Neuropsychological Tests; Risk Factors; Smoking; Statistics as Topic; Triglycerides | 2006 |
Plasma homocysteine and risk of coexisting silent brain infarction in Alzheimer's disease.
Topics: Aged; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Cell Death; Cerebral Infarction; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Genotype; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neurons; Peptide Fragments; Risk Factors; tau Proteins; Vitamin B 12 | 2005 |
Folate, the methionine cycle, and Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Reactive Oxygen Species; S-Adenosylmethionine | 2006 |
Plasma homocysteine, cobalamin/folate status, and vascular disease in a large population of psychogeriatric patients.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Depressive Disorder; Female; Folic Acid; Hematocrit; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Nutritional Status; Population; Sweden; Vascular Diseases; Vitamin B 12 | 2006 |
Abeta peptides as one of the crucial volume transmission signals in the trophic units and their interactions with homocysteine. Physiological implications and relevance for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cell Communication; Corpus Striatum; Extracellular Space; Glial Fibrillary Acidic Protein; Homocysteine; Male; Nerve Net; Neuroglia; Neurons; Pain Threshold; Peptide Fragments; Plaque, Amyloid; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2007 |
Behavioural and psychological symptoms of Alzheimer type dementia are not correlated with plasma homocysteine concentration.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Neuropsychological Tests; Psychological Tests; Severity of Illness Index; Vitamin B 12 | 2006 |
Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Female; Genetic Markers; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2006 |
Homocysteine and electroencephalographic rhythms in Alzheimer disease: a multicentric study.
Topics: Aged; Alzheimer Disease; Biomarkers; Brain; Cognition Disorders; Electroencephalography; Female; Homocysteine; Humans; Male | 2007 |
Relationship of vascular risk to the progression of Alzheimer disease.
Topics: Alzheimer Disease; Apolipoproteins E; Cerebral Arteries; Cerebrovascular Disorders; Cholesterol; Disease Progression; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperlipidemias; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors | 2007 |
Prolonged stress will induce Alzheimer's disease in elderly people by increased release of homocysteic acid.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Homocysteine; Humans; Mice; Models, Neurological; Rats; Stress, Psychological | 2007 |
Relations between homocysteine, folate and vitamin B12 in vascular dementia and in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Risk Factors; Vitamin B 12 | 2007 |
Association between vitamin B6 and white matter hyperintensities in patients with Alzheimer's disease not mediated by homocysteine metabolism.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Homocysteine; Humans; Magnetic Resonance Imaging; Middle Aged; Vitamin B 6 | 2007 |
Folate deficiency and plasma homocysteine during increased oxidative stress.
Topics: Alzheimer Disease; Animals; Apolipoproteins E; Cardiovascular Diseases; Disease Models, Animal; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Transgenic; Oxidative Stress; Risk Factors | 2007 |
Potential biomarkers for dementia in Trinidad and Tobago.
Topics: Aged; Alzheimer Disease; Animals; Antibodies; Biomarkers; Blood Chemical Analysis; C-Reactive Protein; Dementia, Vascular; Diagnosis, Differential; Female; Homocysteine; Humans; Male; Microglia; Middle Aged; Neuropsychological Tests; Predictive Value of Tests; Rats; Trinidad and Tobago | 2007 |
gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells.
Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Antioxidants; Aspartic Acid Endopeptidases; Blotting, Western; Cell Line, Tumor; DNA Methylation; DNA Primers; Folic Acid; Glioblastoma; Homocysteine; Humans; Neuroblastoma; Oxidative Stress; Polymerase Chain Reaction; Presenilin-1; S-Adenosylmethionine; Up-Regulation; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2007 |
Methylenetetrahydrofolate reductase gene and risk of Alzheimer's disease in Koreans.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Asian People; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2008 |
Elevated serum homocysteine levels in male patients with PTSD.
Topics: Adult; Alzheimer Disease; Chronic Disease; Depression; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Schizophrenia; Stress Disorders, Post-Traumatic; Young Adult | 2008 |
Homocysteine induces tau hyperphosphorylation in rats.
Topics: Alzheimer Disease; Animals; Binding Sites; Brain; Brain Chemistry; Homocysteine; Hyperhomocysteinemia; Injections, Intraventricular; Male; Neurofibrillary Tangles; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; Serine; tau Proteins; Time Factors | 2007 |
Mercaptopropionaldehyde from homocysteine: implications for Alzheimer's disease.
Topics: 3-Mercaptopropionic Acid; Aldehydes; Alzheimer Disease; Amyloid beta-Protein Precursor; Chemical Precipitation; Homocysteine; Humans; Neurofibrillary Tangles; Plaque, Amyloid | 2007 |
Plasma aminothiol compounds, but not serum tumor necrosis factor receptor II and soluble receptor for advanced glycation end products, are related to the cognitive impairment in Alzheimer's disease and mild cognitive impairment patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Cysteine; Down-Regulation; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Tumor Necrosis Factor, Type II; Sulfhydryl Compounds; Up-Regulation | 2007 |
Changes in folate, vitamin B12 and homocysteine associated with incident dementia.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Mental Status Schedule; Neuropsychological Tests; Predictive Value of Tests; Prospective Studies; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Apolipoprotein E4; China; Female; Folic Acid; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk Factors; Sex Factors | 2009 |
Synergistic induction of ER stress by homocysteine and beta-amyloid in SH-SY5Y cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum; Folic Acid; Homocysteine; Humans; Models, Biological; Protein Binding; Reactive Oxygen Species; Ultraviolet Rays | 2008 |
Post-methionine load test: A more sensitive tool to reveal hyperhomocysteinemia in Alzheimer patients?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Sensitivity and Specificity | 2008 |
CSF/serum folate gradient: physiology and determinants with special reference to dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood-Brain Barrier; Case-Control Studies; Choroid Plexus; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Risk Factors; Serum Albumin; Vitamin B 12 | 2008 |
Is metabolic evidence for vitamin B-12 and folate deficiency more frequent in elderly patients with Alzheimer's disease?
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Female; Folic Acid Deficiency; Homocysteine; Hospitalization; Humans; Male; Methylmalonic Acid; Reference Values; Vitamin B 12 Deficiency | 1997 |
Total serum homocysteine in senile dementia of Alzheimer type.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biological Transport, Active; Case-Control Studies; Cognition; Creatinine; Diet; Female; Folic Acid; Homocysteine; Humans; Learning; Male; Memory; Prospective Studies; Psychiatric Status Rating Scales; Reference Values; Regression Analysis; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Memory Disorders; Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Risk Factors; Vascular Diseases; Vitamin B 12 | 1998 |
Vascular involvement in cognitive decline and dementia. Epidemiologic evidence from the Rotterdam Study and the Rotterdam Scan Study.
Topics: Aged; Alzheimer Disease; Arteriosclerosis; Atrial Fibrillation; Brain; Cerebrovascular Circulation; Cognition Disorders; Cross-Sectional Studies; Dementia; Diabetes Mellitus; Female; Homocysteine; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Netherlands; Prospective Studies; Risk Factors; Smoking | 2000 |
Leukoaraiosis at presentation and disease progression during follow-up in histologically confirmed cases of dementia.
Topics: Aged; Alzheimer Disease; Blood Pressure; Brain; Dementia, Vascular; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Mental Status Schedule; Retrospective Studies; Tomography, X-Ray Computed | 2000 |
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene and vascular dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Case-Control Studies; Dementia, Vascular; Female; Gene Frequency; Homocysteine; Humans; Israel; Jews; Male; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Polymorphism, Genetic; Tomography, X-Ray Computed | 2000 |
[Alzheimer's disease: from pathology to preventive methods?].
Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins E; Chromosomes, Human, Pair 19; Homocysteine; Humans; Nutritional Status | 2000 |
Treatment of cobalamin deficiency in dementia, evaluated clinically and with cerebral blood flow measurements.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Circulation; Dementia, Vascular; Female; Homocysteine; Humans; Hydroxocobalamin; Injections, Intramuscular; Male; Methylmalonic Acid; Regional Blood Flow; Vitamin B 12 Deficiency | 2000 |
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Dementia; Dementia, Vascular; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Male; Pyridoxine; Reference Values; Vitamin B 12 | 2000 |
Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Copper; Dose-Response Relationship, Drug; Drug Synergism; Homocysteine; Humans; Kinetics; Mice; Mice, Inbred Strains; Neurons; Neurotoxins; Risk Factors | 2001 |
Hyperhomocysteinemia in dementia.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Pilot Projects; Reference Values; Regression Analysis; Risk Factors; Vitamin B 12 | 2000 |
One-carbon metabolism and other biochemical correlates of cognitive impairment as visualized by principal component analysis.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Atrophy; Brain; Cognition Disorders; Dementia, Vascular; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Reference Values; Severity of Illness Index; tau Proteins; Vitamin B 12 | 2001 |
Nutrition. B vitamins.
Topics: Age Factors; Alzheimer Disease; Diet; Homocysteine; Humans; Myocardial Infarction; Vitamin B 12; Vitamin B 6 | 2001 |
Homocysteine and dementias.
Topics: Alzheimer Disease; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2002 |
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Confounding Factors, Epidemiologic; Dementia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Multivariate Analysis; Proportional Hazards Models; Risk Factors | 2002 |
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Cells, Cultured; Diet; Disease Models, Animal; DNA Damage; DNA Repair; Folic Acid Deficiency; Hippocampus; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Transgenic; Neurons; Rats; Uracil | 2002 |
In praise of folic acid.
Topics: Alzheimer Disease; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Spinal Dysraphism; United States | 2002 |
Homocysteine may raise Alzheimer's risk. Keep homocysteine levels in check by getting enough folic acid in your diet.
Topics: Aged; Alzheimer Disease; Biomarkers; Folic Acid; Homocysteine; Humans | 2002 |
Protein phosphatase 2A methylation: a link between elevated plasma homocysteine and Alzheimer's Disease.
Topics: Alzheimer Disease; Homocysteine; Humans; Methylation; Models, Biological; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Risk Factors; tau Proteins | 2002 |
Functional vitamin B(12) deficiency and Alzheimer disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alzheimer Disease; Brain; Homocysteine; Humans; Hyperhomocysteinemia; Oxidation-Reduction; Oxidative Stress; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Plasma homocysteine levels, cerebrovascular risk factors, and cerebral white matter changes (leukoaraiosis) in patients with Alzheimer disease.
Topics: Aged; Alzheimer Disease; Brain; Brain Diseases; Case-Control Studies; Cerebrovascular Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Nerve Fibers; Risk Factors; Tomography, X-Ray Computed | 2002 |
Homocysteine, vitamin B6, and vascular disease in AD patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Angina Pectoris; Brain Infarction; Coronary Disease; Female; Heart Failure; Homocysteine; Humans; Ischemic Attack, Transient; Male; Myocardial Infarction; Odds Ratio; Pyridoxal Phosphate; Stroke; Vascular Diseases; Vitamin B 6 | 2002 |
Relation between plasma homocysteine and Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Homocysteine; Humans; Male; Matched-Pair Analysis; Vascular Diseases | 2002 |
Brain hydrogen sulfide is severely decreased in Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acids; Blotting, Western; Brain; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Humans; Hydrogen Sulfide; S-Adenosylmethionine | 2002 |
Homocysteine and dementia.
Topics: Alzheimer Disease; Brain; Homocysteine; Humans | 2002 |
Homocysteine and dementia.
Topics: Alzheimer Disease; Blood Chemical Analysis; Fasting; Homocysteine; Humans | 2002 |