homocysteine and Alzheimer Disease

homocysteine has been researched along with Alzheimer Disease in 346 studies

Research

Studies (346)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (1.16)18.2507
2000's170 (49.13)29.6817
2010's140 (40.46)24.3611
2020's32 (9.25)2.80

Authors

AuthorsStudies
de Paula, AMB; Engedal, K; Felício, LFF; Kristiansen, KM; Leão, LL; Monteiro-Junior, RS; Santos, SHS; Tangen, GG1
Baldinelli, S; Fiori, C; Luzzi, S; Papiri, G; Silvestrini, M; Toraldo, A; Viticchi, G1
Gupta, JK; Srivastava, R; Varshney, KK; Verma, N1
Abd El Moneim, RA; El-Mezayen, NS; El-Rewini, SH1
Liu, C; Luo, G; Wang, X1
Cicognola, C; Frölich, K; Londos, E; Nyholm, E; Torkpoor, R1
Liu, Q; Liu, X; Meng, Y; Shi, L; Zhang, L; Zhang, W; Zhang, X1
Jia, J; Li, T; Quan, M; Song, Y1
Guo, R; He, J; Quan, L; Zhou, K1
Alexander, GE; Bharadwaj, PK; Habeck, CG; Hishaw, GA; Huentelman, MJ; Raichlen, DA; Song, H; Trouard, TP1
Futschek, IE; Haslacher, H; Lehrner, J; Schernhammer, E; Stögmann, E1
Dionne, IJ; Maltais, M; Rolland, Y; St-Martin, P1
Darabi, M; Hoseinlar, SF; Laghousi, D; Nikanfar, M; Nourazarian, A; Shademan, B1
Bian, J; Jiao, X; Li, Y; Liu, G; Song, Y; Tang, B; Wang, X; Xie, X; Zhang, J; Zhao, Y1
Bottiglieri, T; Fardo, DW; Johnson, SN; Qiao, Q; Rogers, CB; Sudduth, TL; Weekman, EM; Wilcock, DM; Xie, K1
Chung, HW; Hsu, YH; Tu, MC; Wu, WC; Yang, JJ1
An, P; Chen, H; Du, Y; Gao, Y; Huang, G; Ji, Y; Liu, S; Lv, X; Ma, F; Song, A; Sun, C; Wang, G; Wang, X; Xu, W; Zhao, J; Zhou, X1
Berge, G; Bråthen, G; Edlund, AK; Giannisis, A; Grøntvedt, GR; Lauridsen, C; Nielsen, HM; Patra, K; Sando, SB; White, LR1
An, Y; Feng, L; Qin, Z; Tao, L; Wang, Y; Xiao, R; Zhang, X1
Abohamza, E; Berry, T; Moustafa, AA1
Guo, J; Li, Y; Meng, H; Niu, X; Zhang, W; Zhao, Y1
An, DD; Liu, R; Lu, YM; Ohlmeyer, M; Shu, XJ; Wan, L; Wang, JZ; Wang, XC; Wei, H; Westermarck, J; Xie, JZ; Zeng, Y; Zhang, HL1
Al-Shabrawey, M; Alhusban, S; Elsherbiny, NM; Jadeja, R; Kira, D; Martin, P; Samra, YA; Sharma, I; Tawfik, A1
Chen, S; Furuta, Y; Hata, J; Hirakawa, Y; Honda, T; Kitazono, T; Ninomiya, T; Ohara, T; Oishi, E; Sakata, S; Shibata, M; Yoshida, D1
Al-Shabrawey, M; Elsherbiny, NM; Samra, YA; Tawfik, A1
Nazıroğlu, M; Övey, İS1
Liu, B; Pi, T; Shi, J1
Bouyahia, A; de Souto Barreto, P; Fischer, C; Giudici, KV; Lu, WH; Mangin, JF; Rolland, Y; Vellas, B1
Arocha-Oriol, C; Calvo-Rodríguez, M; Díaz-Domínguez, M; Eugenia, M; García-Klibanski, M; Guerra-Hernández, M; Herrera-Javier, D; Jesús, J; Lanyau-Domínguez, Y; Macías-Matos, C; María, G; Noriega-Fernández, L; Sánchez-Gil, Y; Suárez-Medina, R1
Gabelli, C; Reffo, A1
Chen, H; Chen, J; Fu, G; Han, H; Li, X; Wang, F; Wu, W; Zhou, D; Zhou, J1
Cascavilla, L; Ciccone, F; D'Onofrio, G; Germano, C; Greco, A; Lauriola, M; Paris, F1
Adsi, H; Bera, S; Do, TD; Frenkel, D; Gartner, M; Gazit, E; Kreiser, T; Laor Bar-Yosef, D; Levy, D; Oluwatoba, DS; Sade Yazdi, D; Shaham-Niv, S; Sigal, S; Zaguri, D1
Bae, JB; Han, JW; Jhoo, JH; Kim, BJ; Kim, JL; Kim, KW; Kim, SG; Kim, TH; Kwak, KP; Lee, DW; Lee, DY; Lee, JJ; Lee, K; Lee, SB; Moon, SW; Park, JH; Ryu, SH; Song, J; Youn, JC1
Gan, Y; Jiang, H; Li, H; Liu, M; Yao, S; Yin, G; Yin, P; Yu, T; Zhang, Y1
Barrero, C; Li, JG; Merali, S; Praticò, D1
He, J; Huang, M; Lin, Y; Pu, Z; Xu, W1
Bowman, GL; Collino, S; Corthésy, J; Da Silva, L; Dayon, L; Descombes, P; Guiraud, SP; Henry, H; Kussmann, M; Marquis, J; Martin, FJ; Métairon, S; Migliavacca, E; Montoliu, I; Moullet, B; Oikonomidi, A; Popp, J; Tautvydaitė, D; Wojcik, J1
Alexopoulos, P; Arbones, M; Badel, A; Camproux, AC; Delabar, JM; Dubois, B; Feraudet-Tarisse, C; Janel, N; Lagarde, J; Lamari, F; Lamourette, P; Paul, JL; Potier, MC; Sarazin, M; Simon, S1
Ding, S; Sun, J; Wen, S; Zhou, J1
Huang, G; Ji, L; Ma, F; Song, A; Wu, T; Zhang, M; Zhao, J1
Filhine-Trésarrieu, P; Guéant, JL; Levy, J; Namour, F; Oussalah, A1
Chang, CC; Chang, WN; Chen, PC; Chen, SF; Hsu, SW; Huang, CW; Hwang, LC; Lee, CC; Wu, MK1
Farina, N; Hart, K; Jernerén, F; Tabet, N; Turner, C1
Bennett, DA; De Jager, PL; Felsky, D; Nazeri, A; Roostaei, T; Schneider, JA; Voineskos, AN1
Andrieu, S; Bowman, GL; Caussé, E; Cesari, M; Coley, N; De Souto Barreto, P; Hooper, C; Payoux, P; Salabert, AS; Vellas, B; Weiner, M1
Di Meco, A; Li, JG; Praticò, D1
Bosi, C; Brombo, G; Cervellati, C; Morieri, ML; Passaro, A; Trentini, A; Valacchi, G; Zuliani, G; Zurlo, A1
Kim, H; Kim, J; Kwon, Y; Roh, H1
Hamano, T; Hayashi, K; Ikawa, M; Kanaan, NM; Kuriyama, M; Nakamoto, Y; Shirafuji, N; Yamamura, O; Yen, SH; Yoshida, H1
Bao, J; Chen, D; Huang, F; Ke, D; Liu, R; Mahaman, YAR; Salissou, MTM; Wang, JZ; Wang, Q; Wang, X; Wang, Y; Wei, Z; Wu, M; Zhang, B1
Barrero, C; Di Meco, A; Li, JG; Merali, S; Praticò, D1
Benakova, H; Fisar, Z; Hroudova, J; Jirak, R; Kitzlerova, E; Lelkova, P; Martasek, P; Raboch, J; Zverova, M1
Arning, E; Bottiglieri, T; Hoffman, A; Qian, H; Sontag, E; Sontag, JM; Taleski, G; Wasek, B1
Adamkov, M; Kalenska, D; Kovalska, L; Kovalska, M; Lehotsky, J; Tatarkova, Z; Tomascova, A; Tothova, B1
Bhadelia, RA; Folstein, MF; Qiu, WQ; Rosenberg, IH; Scott, TM1
Guo, J; Li, Q; Ni, S; Wang, JZ; Yang, Y1
Cortina-Borja, M; Lehmann, DJ1
Huang, F; Ke, D; Liu, R; Mahaman, YAR; Salissou, MTM; Wang, JZ; Wang, Q; Wang, X; Wang, Y; Xu, Z; Zhang, B; Zhu, F1
Andrews, RD; de Leon, MJ; Ganzer, C; Isaacson, RS; Matthews, DC; Mosconi, L; Osorio, RS; Quinn, C; Sterling, J; Vallabhajosula, S; Walters, MJ1
Caccamo, A; Dave, N; Ferreira, E; Huentelman, MJ; Naymik, M; Oddo, S; Piras, IS; Tran, A; Velazquez, R; Winslow, W1
Chen, S; Zhou, F1
Basun, H; Cederholm, T; Eriksdotter, M; Faxen-Irving, G; Freund-Levi, Y; Hjorth, E; Jernerén, F; Palmblad, J; Refsum, H; Schultzberg, M; Smith, AD; Turner, C; Wahlund, LO1
Ferreirós, N; Fleck, SC; Geisslinger, G; Gurke, R; Schmidt, D; Thomas, D1
Barber, RC; Edwards, M; Hall, JR; Johnson, LA; O'Bryant, SE; Singh, M; Wiechmann, AR; Winter, AS1
Cheek, L; Jones, E; Smith, E; Tabet, N; Veryard, L; Weaving, G; Wickramasinghe, A1
Chang, AY; Chang, CC; Chang, WN; Chang, YT; Chen, NC; Huang, CW; Huang, SH; Lee, CC; Lui, CC1
Fischer, P; Hinterberger, M; Huber, K; Jungwirth, S; Krampla, W; Krugluger, W; Leitha, T; Tragl, KH; Zehetmayer, S1
Fekih-Mrissa, N; Gritli, N; Klai, S; Mansour, M; Mansouri, L; Mrissa, R1
de Jager, CA; Douaud, G; Jacoby, R; Nichols, TE; Refsum, H; Smith, AD; Smith, SM1
Cheng, DM; Huang, CY; Jiang, YG; Kong, HY; Liu, J; Pang, W; Sun, SD1
Cheng, YY; Hong, Y; Hou, Y; Li, YL; Niu, C; Yu, LX1
Chen, J; He, ZF; Lu, YQ; Luo, Y; Wang, Y; Yan, BL; Yu, Q1
Goutzourelas, N; Gubandru, M; Ilie, M; Kouretas, D; Margina, D; Tsarouhas, K; Tsatsakis, AM; Tsitsimpikou, C1
Erkinjuntti, T; Hooshmand, B; Kivipelto, M; Mäkelä, M; Myllykangas, L; Oinas, M; Paetau, A; Polvikoski, T; Scheltens, P; Solomon, A; Sulkava, R; Tanskanen, M; van Straaten, EC1
Bendini, M; Boldrini, P; Di Paola, F; Gallucci, M; Grossi, E; Zanardo, A1
Arab, A; Bogari, N; Elhawary, NA; Hewedi, D; Shaibah, H; Tayeb, MT; Teama, S1
Bergamini, CM; Bosi, C; Cervellati, C; Cremonini, E; Magon, S; Passaro, A; Pilotto, A; Romani, A; Seripa, D; Zuliani, G1
Gröber, U; Kisters, K; Schmidt, J1
Gard, PR; Nilforooshan, R; Richardson, C; Tabet, N; Weaving, G1
Byun, MS; Choe, YM; Choi, HJ; Han, JY; Kim, YK; Lee, DY; Lee, JM; Park, J; Seo, EH; Sohn, BK; Woo, JI; Yoon, EJ1
Barber, RC; Cunningham, R; Edwards, M; Hall, JR; Johnson, LA; O'Bryant, SE; Singh, M; Wiechmann, AR1
Benaková, H; Fisar, Z; Hroudová, J; Jirák, R; Kitzlerová, E; Raboch, J; Zvĕrová, M1
Barrero, C; Chu, J; Li, JG; Merali, S; Praticò, D1
Belarbi, S; Bendini, M; Chelouti, H; Djerdjouri, B; El Hadi Cherifi, M; Kacimi, G; Khelil, M; Nazef, K; Tazir, M1
Beydoun, HA; Beydoun, MA; Gamaldo, AA; Teel, A; Wang, Y; Zonderman, AB1
Chen, H; Cui, W; Kong, L; Wang, C; Wang, J; Yi, L; Yu, H; Zheng, Z1
Li, JG; Praticò, D1
Baierle, M; Bordignon, S; Breusing, N; Duarte, MM; Emanuelli, T; Garcia, SC; Grune, T; Oldenburg, L; Somacal, S; Trentini, CM; Veit, JC; Vencato, PH; Zibetti, M1
Devčić, S; Glamuzina, L; Mihanovic, M; Ruljancic, N1
Rabinovitz, S; Yehuda, S1
Bian, J; Chen, C; Cheng, Y; Gao, S; Hake, AM; Hendrie, HC; Jin, Y; Kettler, C; Li, P; Liu, J; Ma, F; Murrell, JR; Su, L; Unverzagt, FW; Yang, L1
Joshi, SH; Madsen, SK; Rajagopalan, P; Thompson, PM; Toga, AW1
Chang, N; Jang, W; Kim, G; Kim, H; Kim, SY1
Chen, H; Huang, G; Ji, L; Ji, Y; Liu, S; Ma, F; Wu, T; Zhang, M; Zheng, M; Zhou, Y1
Coşar, A; Gültepe, M; Ipçioğlu, OM; Ozcan, O1
Cavallaro, RA; Desiderio, C; Di Napoli, A; Fuso, A; Gervasoni, J; Giardina, B; Nicolia, V; Persichilli, S; Scarpa, S1
Ji, HF; Shen, L1
Chung, YI; Ha, JK; Kim, HJ; Kim, JH; Kim, TH; Kim, YH; Lee, BD; Lee, YM; Moon, E; Mun, CW; Park, JM1
Kalani, A; Kamat, PK; Kyles, P; Tyagi, N1
Bonuccelli, U; Bosco, P; Coppedè, F; Haslberger, A; Migliore, L; Petrozzi, L; Ragalmuto, A; Salluzzo, MG; Siciliano, G; Stoccoro, A; Tannorella, P; Tognoni, G1
Atienza, M; Cantero, JL; Llado-Saz, S1
Fenech, M; Thomas, P1
Albaladejo, MD; Morillas-Ruiz, JM; Rubio-Perez, JM; Vidal-Guevara, ML; Zafrilla, P1
Dar, TA; Kumar, T; Sharma, GS; Singh, LR1
Chwedorowicz, A; Chwedorowicz, R; Gustaw Rothenberg, K; Raszewski, G1
Hao, F; Hu, Q; Li, J; Teng, W; Wang, N1
Bäckman, L; Ertl-Wagner, B; Fratiglioni, L; Hooshmand, B; Kalpouzos, G; Kåreholt, I; Kivipelto, M; Laukka, EJ; Mangialasche, F; Mühlmann, M; Refsum, H; Smith, AD; Solomon, A; Wang, R1
Glick, JL; McMillan, PA1
Cui, Y; Kong, X; Wei, W; Wei, Y; Zhang, J; Zheng, L1
Narr, KL; Roussotte, FF; Small, GW; Thompson, PM1
Coppedè, F; Grossi, E; Migliore, L; Stoccoro, A; Tannorella, P1
Gao, XJ; Gong, JB; Ma, J; Qian, LJ; Wang, SD; Xie, F; Zhang, L; Zhao, Y1
Grant, WB1
Hasegawa, T; Ukai, W1
Nichols, J1
Beiser, AS; Benjamin, EJ; Chen, TC; Kaess, B; Preis, SR; Rahman, F; Satizabal, C; Seshadri, S; Vasan, RS; Weinstein, G1
Cui, XP; Mu, JS; Ye, JX; Zhang, DM1
Oláh, E; V Oláh, A; Varga, P1
Fuchs, D; Greilberger, J; Greilberger, M; Koidl, C; Lamprecht, M; Leblhuber, F; Oettl, K; Schroecksnadel, K1
Shea, TB; Tchantchou, F1
Gustafson, L; Hultberg, B; Nilsson, K9
Aisen, PS; Bottiglieri, T; Diaz-Arrastia, R; Jin, S; Sano, M; Schneider, LS; Stokes, KT; Thal, LJ; Thomas, RG; van Dyck, CH; Weiner, MF1
Bennett, DA; Clarke, RJ1
Cao, D; Desmond, R; Lah, JJ; Levey, AI; Li, L; Rahman, A; Zamrini, E1
Lucassen, PJ; Marlatt, MW; Perry, G; Smith, MA; Zhu, X1
Green, R; Luchsinger, JA; Mayeux, R; Miller, J; Tang, MX1
Huang, H; Jiang, P; Liu, XQ; Yan, Y1
Barcikowska, M; Chodakowska-Zebrowska, M; Czapski, GA; Gabryelewicz, T; Karciauskas, G; Kobryś, M; Pfeffer, A; Religa, D; Strosznajder, JB; Styczyńska, M1
de la Plata, CM; Diaz-Arrastia, R; Fields, BA; Gong, YH; Hynan, LS; Qu, BX; Rosenberg, RN; Weiner, MF; Womack, KB1
Almeida, S; Cascalheira, JF; Castro, R; Domingues, FC; Faria, MC; João, SS; Palmeira, M; Pinhanços, SS1
Dai, D; Li, K; Liu, S; Wang, B; Yao, L; Yao, S1
Bednarska-Makaruk, M; Bochyńska, A; Graban, A; Lipczyńska-Łojkowska, W; Rodo, M; Ryglewicz, D; Wehr, H1
Ochudło, S; Opala, G; Siuda, J; Targosz-Gajniak, M1
Pratico, D1
Machanic, BI1
Colla, M; Endres, M; Kronenberg, G1
Annerbo, S; Bäckman, L; Fratiglioni, L; Hultdin, J; Kivipelto, M; Lökk, J; Viitanen, M1
Beaumont, H; Jacoby, R; King, E; Oulhaj, A; Refsum, H; Smith, AD; Williams, J1
Hiraoka, M; Kagawa, Y; Kageyama, M1
Cvetanovska, G; Frommann, I; Jessen, F; Kölsch, H; Kornhuber, J; Lewczuk, P; Linnebank, M; Maier, W; Popp, J; Smulders, Y1
Humpel, C; Pirchl, M1
Baboolal, N; Davis, G; McRae, A; Nayak, S1
Annerbo, S; Kivipelto, M; Lokk, J1
Alajbegovic, A; Fajkic, A; Hadzovic-Dzuvo, A; Kulo, A; Lepara, D; Lepara, O; Nakas-Icindic, E; Sofic, E; Valjevac, A; Zaciragic, A1
Gould, TJ; Kruger, WD; Portugal, GS; Pratico, D; Wang, H; Zhuo, JM1
Abe, T; Isobe, C; Terayama, Y1
Escobedo, JO; Lim, S; Samoei, GK; Sibrian-Vazquez, M; Strongin, RM1
Hasegawa, T; Kitazawa, M; LaFerla, FM; Mikoda, N1
Chang, RC; Ho, YS; So, KF; Yang, XF; Yu, MS; Yuen, WH1
Griffiths, HR; Li, L; Nelles, G; Polidori, MC; Sies, H; Stahl, W; Willets, RS1
Jang, Y; Kwon, YH; Park, YJ1
Bosco, P; Cento, RM; Costantini, B; Ferri, R; Lanzone, A; Macrì, F; Perri, C; Proto, C; Suriano, R; Villa, P1
Cornelli, U1
Prakasam, A; Ramesh, BN; Rao, KS; Rao, TS; Sambamurti, K1
Borroni, B; Conti, E; Ferrarese, C; Galimberti, G; Isella, V; Padovani, A; Perlangeli, MV; Piazza, F; Pogliani, EM; Speranza, T1
Lovestone, S; Thambisetty, M1
Hudson, PR; McCaddon, A1
Chang, PY; Chen, CH; Lu, SC1
Handels, R; van Rossum, IA; Visser, PJ; Vos, S1
Aisen, PS; Blennow, K; Clark, CM; Dean, R; Jack, CR; Jagust, W; Korecka, M; Lee, VM; Lewczuk, P; Petersen, RC; Potter, WZ; Shaw, LM; Siemers, E; Simon, A; Soares, H; Toga, AW; Trojanowski, JQ; Vandeerstichele, H; Weiner, MW1
Chang, CC; Chang, WN; Chen, C; Chen, CF; Huang, CW; Juang, YY; Lin, YT; Lu, CH; Lui, CC; Tu, MC; Wang, YL1
Blom, H; Cvetanovska, G; Farkas, M; Jessen, F; Kölsch, H; Kulic, L; Linnebank, M; Popp, J; Semmler, A; Smith, D; Smulders, Y; Stoffel-Wagner, B; Weller, M1
Basu, S; Chakrabarti, S; Pal, K; Saha, A; Sinha, M1
Chen, CS; Chou, MC; Lai, CL; Liao, YC; Liu, CK; Yang, YH; Yeh, YC; Yen, CF1
Gong, YH; Hynan, LS; Qu, BX; Rosenberg, RN; Rossetti, H; Weiner, MF; Womack, KB1
Chang, CC; Chang, WN; Chen, C; Chen, CF; Chen, NC; Huang, CW; Lin, YT; Lui, CC; Tu, MC; Wang, YL1
Sui, R; Zhang, L1
Albaladejo, MD; Morillas-Ruiz, JM; Parra, S; Rubio-Perez, JM; Vidal-Guevara, ML; Zafrilla, P1
Adachi, K; Akatsu, H; Hosono, T; Jung, CG; Komano, H; Michikawa, M; Minagawa, H; Ohtsuka, C; Takahashi, S; Terayama, Y; Wakita, H; Watanabe, A1
Ahtiluoto, S; Hooshmand, B; Kåreholt, I; Kivipelto, M; Laatikainen, T; Leiviskä, J; Rusanen, M; Soininen, H; Solomon, A; Winblad, B1
Fuchs, D; Greilberger, J; Greilberger, M; Leblhuber, F; Tafeit, E; Wintersteiger, R1
Ahmed, HH1
Choi, KC; Kwok, T; Lam, LC; Law, CB; Lee, J; Pan, PC; Yung, CY1
Sachdev, PS1
Ben Othman, L; Bennamou, S; Charfeddine, B; Dridi, H; Golmard, JL; Jacob, N; Lammouchi, T; Limem, K; Smach, MA1
Hua, X; Jack, CR; Rajagopalan, P; Thompson, PM; Toga, AW; Weiner, MW1
Callahan, CM; Hendrie, HC1
Praticò, D; Wang, H; Zhuo, JM1
Cheung, MW; Fu, E; Ho, RC; Mak, A; Ng, A; Win, HH; Zaw, MH1
Broadbent, D; Gurton, J; Houston, L; Moore, V; Nilforooshan, R; Tabet, N; Weaving, G1
Ames, D; Bush, AI; Ellis, KA; Faux, NG; Fowler, CJ; Laws, SM; Martins, RN; Masters, CL; Pertile, KK; Porter, L; Rembach, A; Rowe, CC; Rumble, RL; Szoeke, C; Taddei, K; Taddei, T; Trounson, BO; Villemagne, VL; Ward, V1
Chen, Z; Guo, ZY; Hu, J; Liu, D; Tan, L; Wang, JZ; Wang, Q; Zhao, N; Zhou, P; Zhu, LQ1
Caldarazzo lenco, E; Coppedè, F; Migheli, F; Migliore, L; Monzani, F; Nacmias, B; Pezzini, I; Piaceri, I; Polini, A; Ricci, G; Siciliano, G; Sorbi, S; Tannorella, P1
Chang, YS; Chen, CS; Huang, MF; Yeh, YC1
Alexopoulos, P; Bickel, H; Kurz, A; Perneczky, R1
Ahmadian, S; Aryapour, H; Hoveizi, E; Karima, O; Khodadadi, S; Riazi, GH1
Abbiati, V; Emanuele, E; Martinelli, V; Ricevuti, G1
Borowczyk, K; Jakubowski, H; Shih, DM1
Jagust, WJ; Lo, RY1
Fujishiro, H; Hasegawa, T; Hatano, T; Hattori, N; Ichiba, M; Iseki, E; Kasanuki, K; Matsumoto, SE; Tabira, T; Yamada, T1
Jakubowski, H; Perła-Kaján, J1
Arlt, S; Böger, RH; Jahn, H; Jessen, F; Kölsch, H; Linnebank, M; Popp, J; Schwedhelm, E; Smulders, Y1
Chang, N; Kim, G; Kim, H; Kim, KN; Kim, SY; Son, JI; Tamura, T1
Arıoğul, S; Cankurtaran, ES; Cankurtaran, M; Halil, M; Kuyumcu, ME; Oztürk, ZA; Ulger, Z; Yavuz, BB; Yesil, Y1
Morris, MS2
Chai, GS; Cheng, XS; Jiang, X; Liu, GP; Ma, ZW; Ni, ZF; Wang, JZ; Wang, Q; Xie, AJ1
Cacciapuoti, F1
Czapski, GA; Maruszak, A; Safranow, K; Strosznajder, JB; Styczyńska, M; Żekanowski, C1
Sano, M1
Korczyn, AD1
Dynan, KB; Lawson, JT; McIlroy, SP; Passmore, AP; Patterson, CC1
Agosti, C; Borroni, B; Di Luca, M; Padovani, A; Panzali, AF1
Lyons-Weiler, J; Rogers, E; Shea, TB1
O'Connell, TC; Williams, JH1
Breteler, MM; Clarke, R; den Heijer, T; Hofman, A; Koudstaal, PJ; Oudkerk, M; Vermeer, SE1
Barber, J; Davies, G; Hill, D; Hudson, P; Lloyd, A; McCaddon, A; Regland, B1
Mattson, MP; Shea, TB1
Mattson, MP1
Miller, AL1
Leboeuf, R1
Bleich, S; Falkai, P; Kessler, H; Supprian, T1
Blom, HJ; Bosma, H; Bosmans, E; De Bruijn, C; de Vente, J; Delanghe, J; Jolles, J; Lütjohann, D; Maes, M; Steinbusch, HW; Teunissen, CE; van Boxtel, MP; von Bergmann, K; Wauters, A1
Chan, SL; Mattson, MP; Pak, KJ1
Debanne, SM; Friedland, RP; Jacobsen, DW; Lerner, AJ; Mizrahi, EH; Petot, GJ; Traore, F1
Barcikowska, M; Chodakowska, M; Gabryelewicz, T; Golebiowski, M; Luczywek, E; Peplonska, B; Pfeffer, A; Religa, D; Stepien, K; Styczynska, M; Wasiak, B; Winblad, B1
Seshadri, S; Wolf, PA1
Bleich, S; Kornhuber, J; Wiltfang, J1
Selley, ML3
Peskin, ER; Pfeiffer, EA; Porsteinsson, AP; Schneider, LS1
Costa, M; Hoff, AL; Sommer, BR1
Czeizel, E; Kalina, A1
Religa, D; Winblad, B1
Sachdev, P1
Anello, G; Bosco, P; Caraci, F; Daval, JL; Ferri, R; Guéant, JL; Guéant-Rodríguez, RM; Namour, B; Pourié, G; Romano, A; Spada, R1
Marcusson, J; Nägga, K; Rådberg, C1
Isoe-Wada, K; Kowa, H; Kusumi, M; Nakashima, K; Nakaso, K; Takeshima, T; Urakami, K; Wakutani, Y; Yano, H; Yasui, K1
Qi, JS; Qiao, JT; Qin, Y1
Dwyer, BE; Perry, G; Raina, AK; Smith, MA1
Arai, H; Maruyama, M; Matsui, T; Nemoto, M; Ootsuki, M; Sasaki, H; Tanji, H; Tomita, N1
Combrinck, M; Hogervorst, E; Smith, AD; van Osch, LA1
Green, R; Luchsinger, JA; Mayeux, R; Miller, J; Shea, S; Tang, MX1
Anello, G; Bosco, P; Caraci, F; Ferri, R; Guéant, JL; Guéant-Rodríguez, RM; Namour, B; Romano, A; Spada, RS; Tringali, G1
Acres, J; Almeida, OP; Flicker, L; Jamrozik, K; Martins, RN; Norman, P; Taddei, K; Thomas, J1
Bicíková, M; Hampl, R; Havlíková, H; Hill, M; Jirák, R; Rípová, D; Tallová, J1
Forloni, G; Fragiacomo, C; Lucca, U; Pezzati, R; Quadri, P; Tettamanti, M; Zanda, E1
Davies, G; Duguid, J; Gray, R; Hill, D; Hudson, P; McCaddon, A; Tandy, S1
Fowler, B; Heun, R; Jeub, M; Klockgether, T; Koch, HG; Kölsch, H; Linnebank, A; Linnebank, M; Suormala, T; Wüllner, U1
Alagona, G; Bella, R; Carnemolla, A; Ferri, R; Malaguarnera, M; Pennisi, G1
Agnati, LF; Antonelli, F; Cortelli, P; Fuxe, K; Galantucci, M; Genedani, S; Guidolin, D; Rasio, G1
Adunsky, A; Bowirrat, A; Debanne, SM; Dibello, PM; Friedland, RP; Jacobsen, DW; Korczyn, AD; Lerner, AJ; Mizrahi, EH; Petot, GJ; Traore, F1
Agnati, LF; Ferré, S; Filaferro, M; Franco, R; Fuxe, K; Galantucci, M; Genedani, S; Mora, F; Rasio, G; Saltini, S1
Cavallaro, RA; D'Anselmi, F; Fuso, A; Scarpa, S; Seminara, L1
Harbrecht, U; Hentschel, F; Heun, R; Jessen, F; Kölsch, H; Kreis, M; Linnebank, M; Lütjohann, D; Maier, W; Schulz, A; Thelen, KM; von Bergmann, K; Wüllner, U1
Huang, MH; Kado, DM; Karlamangla, AS; Rowe, JW; Seeman, TE; Selhub, J; Troen, A1
Bresolin, N; Comi, GP; Del Bo, R; Dominici, R; Fenoglio, C; Forloni, G; Galbiati, S; Galimberti, D; Gatti, A; Guidi, I; Lovati, C; Mariani, C; Pomati, S; Scarpini, E; Venturelli, E; Virgilio, R1
Andrews, LG; Liu, L; Tollefsbol, TO; Ulrey, CL1
Anello, G; Barone, C; Bosco, P; Gérard, P; Guéant, JL; Guéant-Rodríguez, RM; Romano, A; Romano, C1
Araki, W; Hasegawa, T; Jo, DG; Mattson, MP; Nakagawa, M; Saito, T; Ukai, W; Xu, X; Yamada, T1
Domínguez, RO; Famulari, AL; Guareschi, EM; Marschoff, ER; Pagano, MA; Serra, JA1
Isobe, C; Murata, T; Sato, C; Terayama, Y1
Flirski, M; Sobow, T1
Bindels, JG; Blom, HJ; de Groot, LC; Hoefnagels, WH; Manders, M; van Staveren, WA; Vasse, E1
Almeida, OP; Flicker, L; Lautenschlager, NT; Leedman, P; Vasikaran, S1
Annerbo, S; Lökk, J; Wahlund, LO1
Brunetti, N; Forti, P; Licastro, F; Maioli, F; Martelli, M; Porcellini, E; Ravaglia, G; Servadei, L1
Dwyer, BE; Perry, G; Smith, MA; Takeda, A; Zhu, X1
Nagy, Z1
Aupetit, J; Janel, N; Santiard-Baron, D1
Arning, E; Barbé, F; Bottiglieri, T; Franck, P; Montagne, P; Nicolas, JP; Serot, JM1
Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M1
Bastagli, L; Bianchin, M; Bolondi, L; Chiappelli, M; Licastro, F; Maioli, F; Martelli, M; Montesi, F; Paola, F; Ravaglia, G; Tumini, E1
McCaddon, A; Regland, B1
Baiguera, S; Conconi, MT; Di Liddo, R; Folin, M; Gallucci, M; Parnigotto, PP; Zanardo, A1
Ke, XY; Liu, Y; Shen, W; Zhang, YD1
Cruz-Sanchez, F; DeRosa, S; Howard, A; Pacheco-Quinto, J; Pappolla, MA; Petanceska, S; Refolo, L; Rodriguez de Turco, EB; Sambamurti, K1
Selhub, J1
Thompson, J1
Bauer, K; Fischer, P; Huber, K; Jungwirth, S; Tragl, KH; Zehetmayer, S1
Arai, H; Furukawa, K; Higuchi, S; Iwasaki, K; Maruyama, M; Matsui, T; Matsushita, S; Nemoto, M; Ootsuki, M; Seki, T; Tanji, H; Tomita, N; Yao, H; Yoshida, Y; Yuzuriha, T1
Shea, TB1
McCaddon, A1
Seshadri, S1
Arai, H1
Agnati, LF; Filaferro, M; Forni, A; Franco, R; Fuxe, K; Genedani, S; Leo, G; Woods, AS1
Iversen, SA; Lyons, B; Rafi, H; Tabet, N; Weaving, G1
Sato, Y1
Cabral-Filho, JE; Cavalcanti, MN; D'Almeida, V; da Silva, VC; de Brito-Marques, PR; Freitas, EM; Muniz, MT; Ramos, FJ1
Anello, G; Babiloni, C; Bartesaghi, S; Benussi, L; Binetti, G; Bosco, P; Cassetta, E; Del Percio, C; Ferri, R; Frisoni, G; Ghidoni, R; Gurzì, M; Lanuzza, B; Lizio, R; Rossini, PM; Squitti, R; Tombini, M1
Archetti, S; Borroni, B; Cesana, BM; Ferrari, M; Padovani, A1
Hasegawa, T1
Boldyrev, AA; Johnson, P1
Karaman, Y; Köseoglu, E1
Barkhof, F; Blankenstein, MA; Bouwman, F; Jakobs, C; Mulder, C; Scheltens, P; van der Flier, WM; Veerhuis, R; Verhoeven, NM1
Bonham, J; Connelly, PJ; Cousland, G; Prentice, NP1
Chan, A; Chen, S; Rogers, EJ1
Baboolal, NS; Davis, GK; McKell, S; McRae, A; Ramchandani, J; Seales, D1
Luchsinger, JA; Noble, JM; Scarmeas, N1
Cavallaro, RA; Confaloni, A; D'Anselmi, F; Fuso, A; Piscopo, P; Scarpa, S; Zampelli, A1
Kim, JM; Kim, SW; Shin, HY; Shin, IS; Stewart, R; Yang, SJ; Yoon, JS2
Dwolatzky, T; Kaplan, Z; Kotler, M; Levine, J; Roitman, S; Sela, BA; Spivak, B; Timinsky, I; Vishne, T1
Luo, Y; Wang, J; Yang, X; Zhou, X1
Chen, RC; Chen, ST; Chien, KL; Lu, CJ; Sun, Y1
Das, UN1
Toohey, JI1
De la Fuente, M; Frank, A; Hernanz, A; Navarro, M1
Bi, XH; Zhang, JW; Zhang, ZX; Zhao, HL1
Cho, HK; Kim, HJ; Kwon, YH1
Antolini, L; Conti, E; DeFilippi, F; Facheris, M; Fenaroli, F; Ferrarese, C; Galimberti, G; Isella, V; Perlangeli, V; Piazza, F; Zini, M1
Hagnelius, NO; Nilsson, TK; Wahlund, LO1
Dejaeger, E; Dereymaeker, L; Ghekiere, V; Joosten, E; Lesaffre, E; Pelemans, W; Riezler, R1
Cattell, H; Davies, G; Hudson, P; McCaddon, A; Tandy, S1
Clarke, R; Jobst, KA; Refsum, H; Smith, AD; Sutton, L; Ueland, PM1
Miller, JW1
Breteler, MM1
Barnetson, L; Budge, M; Bungay, H; Clarke, R; Esiri, M; Frost, C; Joachim, C; King, E; Molyneux, A; Morris, J; Smith, AD1
Bejarano-Achache, I; Blumenfeld, A; Doron, D; Idelson, M; Pollak, A; Pollak, RD1
Adoue, D; Albarède, JL; Andrieu, S; Guyonnet, S; Nourhashémi, F; Ousset, PJ; Rolland, Y; Vellas, B1
Fäldt, R; Gustafson, L; Hultberg, B; Nilsson, K; Warkentin, S1
Bargossi, AM; Caldarera, M; Cavalli, G; Facchini, A; Forti, P; Franceschi, C; Grossi, G; Maioli, F; Mariani, E; Ravaglia, G; Vettori, C1
Beilby, J; Rossi, E1
Barrow, CJ; Beyreuther, K; Bush, AI; Cappai, R; Huang, X; Jobling, MF; Masters, CL; White, AR1
Artner-Dworzak, E; Fuchs, D; Leblhuber, F; Reibnegger, G; Vrecko, K; Walli, J; Widner, B1
Rosenberg, IH1
Blennow, K; Gottfries, CG; Gottfries, J; Lehmann, MW; Regland, B1
González-Gross, M; Marcos, A; Pietrzik, K1
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Loscalzo, J1
Beiser, A; D'Agostino, RB; Jacques, PF; Rosenberg, IH; Selhub, J; Seshadri, S; Wilson, PW; Wolf, PA1
Cutler, RG; Evans, M; Haughey, N; Kruman, II; Kruman, Y; Kumaravel, TS; Lee, J; Lohani, A; Mattson, MP; Pedersen, WA1
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Friedland, RP; Jacobsen, DW; Mizrahi, EH1
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Davies, G; Hudson, P; McCaddon, A; Regland, B1
Budge, M; Hogervorst, E; Molyneux, A; Ribeiro, HM; Smith, AD1
Green, R; Jagust, WJ; Miller, JW; Mungas, DM; Reed, BR1
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Rogers, E; Shea, TB1
Auer, J; Berent, R; Eber, B1

Reviews

61 review(s) available for homocysteine and Alzheimer Disease

ArticleYear
A disease-modifying treatment for Alzheimer's disease: focus on the trans-sulfuration pathway.
    Reviews in the neurosciences, 2020, Apr-28, Volume: 31, Issue:3

    Topics: Alzheimer Disease; Animals; Homocysteine; Humans; Molybdenum; Neuroprotective Agents; Selenocysteine

2020
Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction.
    Biomolecules, 2020, 07-29, Volume: 10, Issue:8

    Topics: Aging; Alzheimer Disease; Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Endoplasmic Reticulum Stress; Homocysteine; Humans; Hyperhomocysteinemia; Macular Degeneration; Oxidative Stress

2020
Abnormal Homocysteine Metabolism: An Insight of Alzheimer's Disease from DNA Methylation.
    Behavioural neurology, 2020, Volume: 2020

    Topics: Aged; Alzheimer Disease; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Neurodegenerative Diseases

2020
Association of
    The American journal of clinical nutrition, 2017, Volume: 106, Issue:4

    Topics: Adult; Aged; Alleles; Alzheimer Disease; Carbon; Child; Congenital Abnormalities; Female; Genotype; Homocysteine; Humans; Male; Methylmalonic Acid; Neoplasms; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; White People

2017
Dissecting the Role of 5-Lipoxygenase in the Homocysteine-Induced Alzheimer's Disease Pathology.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 62, Issue:3

    Topics: Alzheimer Disease; Animals; Arachidonate 5-Lipoxygenase; Brain; Epigenesis, Genetic; Homocysteine; Humans; Hyperhomocysteinemia

2018
Causes of hyperhomocysteinemia and its pathological significance.
    Archives of pharmacal research, 2018, Volume: 41, Issue:4

    Topics: Alzheimer Disease; Anemia; Animals; Biomarkers; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors

2018
Hyperhomocysteinemia and risk of incident cognitive outcomes: An updated dose-response meta-analysis of prospective cohort studies.
    Ageing research reviews, 2019, Volume: 51

    Topics: Alzheimer Disease; Cognition; Cognitive Dysfunction; Cohort Studies; Dementia, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Prospective Studies; Risk Factors

2019
Neuroenhancement with vitamin B12-underestimated neurological significance.
    Nutrients, 2013, Dec-12, Volume: 5, Issue:12

    Topics: Alzheimer Disease; Brain; Cognition; Homocysteine; Humans; Incidence; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2013
Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis.
    BMC public health, 2014, Jun-24, Volume: 14

    Topics: Alcohol Drinking; Alzheimer Disease; Antioxidants; Caffeine; Cognition; Cognition Disorders; Dementia; Diet; Educational Status; Exercise; Fatty Acids, Omega-3; Female; Homocysteine; Humans; Male; Smoking

2014
Folate and homocysteine metabolisms and their roles in the biochemical basis of neuropsychiatry.
    Turkish journal of medical sciences, 2014, Volume: 44, Issue:1

    Topics: Alzheimer Disease; Autistic Disorder; Biological Transport; Folic Acid; Homocysteine; Humans; Psychotic Disorders

2014
Associations between Homocysteine, Folic Acid, Vitamin B12 and Alzheimer's Disease: Insights from Meta-Analyses.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 46, Issue:3

    Topics: Age Factors; Alzheimer Disease; Databases, Bibliographic; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12

2015
Protein N-homocysteinylation: From cellular toxicity to neurodegeneration.
    Biochimica et biophysica acta, 2015, Volume: 1850, Issue:11

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Homocysteine; Humans; Neurodegenerative Diseases; Neurons; Prions; Protein Aggregates

2015
Homocysteine and Alzheimer's Disease: Evidence for a Causal Link from Mendelian Randomization.
    Journal of Alzheimer's disease : JAD, 2016, 03-22, Volume: 52, Issue:2

    Topics: Alzheimer Disease; Data Interpretation, Statistical; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide

2016
Using Multicountry Ecological and Observational Studies to Determine Dietary Risk Factors for Alzheimer's Disease.
    Journal of the American College of Nutrition, 2016, Volume: 35, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholesterol; Cooking; Culture; Dairy Products; Diet; Diet, Western; Dietary Carbohydrates; Dietary Fats; Ecology; Glycation End Products, Advanced; Homocysteine; Hot Temperature; Humans; Meat; Metals; Obesity; Oxidative Stress; Risk Factors; Vitamin D

2016
Efficacy of Vitamin B Supplementation on Cognition in Elderly Patients With Cognitive-Related Diseases.
    Journal of geriatric psychiatry and neurology, 2017, Volume: 30, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2017
[Biochemical alterations in patients with Down syndrome].
    Orvosi hetilap, 2008, Jun-29, Volume: 149, Issue:26

    Topics: Acetylglucosaminidase; Adult; Alzheimer Disease; Antioxidants; Bilirubin; Blood Proteins; Cystathionine beta-Synthase; Disease Progression; Down Syndrome; Ferritins; Folic Acid; Homocysteine; Humans; Learning; Nootropic Agents; Quality of Life; S100 Proteins; Serum Albumin; Superoxide Dismutase; Transferrin; Vitamin B 12

2008
Plasma homocysteine and vascular disease in elderly patients with mental illness.
    Clinical chemistry and laboratory medicine, 2008, Volume: 46, Issue:11

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Dementia; Homocysteine; Humans; Mental Disorders; Risk Factors; Vascular Diseases

2008
Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies.
    Journal of Alzheimer's disease : JAD, 2008, Volume: 15, Issue:2

    Topics: Alzheimer Disease; Cerebrovascular Disorders; Clinical Trials as Topic; Dementia; Homocysteine; Humans; Neurodegenerative Diseases; Oxidative Stress

2008
Folic acid, neurodegenerative and neuropsychiatric disease.
    Current molecular medicine, 2009, Volume: 9, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Brain; Clinical Trials as Topic; Dementia, Vascular; Depression; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Molecular Structure; Neurodegenerative Diseases; Neuronal Plasticity; Stroke; Vitamin B Complex

2009
Neuronutrition and Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 19, Issue:4

    Topics: Aged; Alcohol Drinking; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Avitaminosis; Brain; Diet; Energy Intake; Female; Homocysteine; Humans; Hypercholesterolemia; Male; Middle Aged; Nerve Degeneration; Nutrition Therapy; Oxidative Stress; Phosphorylation; Point Mutation; Vitamin E

2010
Blood-based biomarkers of Alzheimer's disease: challenging but feasible.
    Biomarkers in medicine, 2010, Volume: 4, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; C-Reactive Protein; Genetic Markers; Homocysteine; Humans; Longitudinal Studies; Proteomics; RNA

2010
L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline.
    CNS spectrums, 2010, Volume: 15, Issue:1 Suppl 1

    Topics: Acetylcysteine; Alzheimer Disease; Cognition Disorders; Free Radical Scavengers; Homocysteine; Humans; Oxidative Stress; Plaque, Amyloid; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex

2010
Biomarkers as predictors for conversion from mild cognitive impairment to Alzheimer-type dementia: implications for trial design.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Clinical Trials as Topic; Cognition Disorders; Disease Progression; Homocysteine; Humans; Lipid Metabolism; Peptide Fragments; tau Proteins

2010
Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2010, Volume: 6, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Biomarkers; Cognition Disorders; Cross-Sectional Studies; Diagnostic Imaging; Homocysteine; Humans; Isoprostanes; Peptide Fragments; Positron-Emission Tomography; Prospective Studies; Reproducibility of Results; tau Proteins; Thiazoles

2010
Is hyperhomocysteinemia an Alzheimer's disease (AD) risk factor, an AD marker, or neither?
    Trends in pharmacological sciences, 2011, Volume: 32, Issue:9

    Topics: Alzheimer Disease; Animals; Biomarkers; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors

2011
Is high homocysteine level a risk factor for cognitive decline in elderly? A systematic review, meta-analysis, and meta-regression.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2011, Volume: 19, Issue:7

    Topics: Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Regression Analysis; Risk Factors; Vitamin B 12

2011
Linking atherosclerosis to Alzheimer's disease: focus on biomarkers.
    Frontiers in bioscience (Elite edition), 2012, 01-01, Volume: 4, Issue:2

    Topics: Alzheimer Disease; Atherosclerosis; Biomarkers; C-Reactive Protein; Cystatin C; Homocysteine; Humans; Lipoprotein(a); Osteoprotegerin; Receptor for Advanced Glycation End Products; Receptors, Immunologic

2012
Paraoxonase 1 and homocysteine metabolism.
    Amino acids, 2012, Volume: 43, Issue:4

    Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Atherosclerosis; Coronary Artery Disease; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipoproteins, HDL; Mice; Oxidative Stress; Stroke

2012
The role of B vitamins in preventing and treating cognitive impairment and decline.
    Advances in nutrition (Bethesda, Md.), 2012, Nov-01, Volume: 3, Issue:6

    Topics: Alzheimer Disease; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylation; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency

2012
Lowering homocysteine levels with folic acid and B-vitamins do not reduce early atherosclerosis, but could interfere with cognitive decline and Alzheimer's disease.
    Journal of thrombosis and thrombolysis, 2013, Volume: 36, Issue:3

    Topics: Alzheimer Disease; Atherosclerosis; Cognition; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex

2013
Prevention of Alzheimer's disease: where we stand.
    Current neurology and neuroscience reports, 2002, Volume: 2, Issue:5

    Topics: Alzheimer Disease; Anti-Inflammatory Agents; Cognition; Estrogen Replacement Therapy; Female; Ginkgo biloba; Homocysteine; Humans; Lipid Metabolism; Male; Primary Prevention

2002
Homocysteine, folate deprivation and Alzheimer neuropathology.
    Journal of Alzheimer's disease : JAD, 2002, Volume: 4, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Nerve Degeneration

2002
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
    Trends in neurosciences, 2003, Volume: 26, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke

2003
The methionine-homocysteine cycle and its effects on cognitive diseases.
    Alternative medicine review : a journal of clinical therapeutic, 2003, Volume: 8, Issue:1

    Topics: Alzheimer Disease; Cardiovascular Diseases; Cognition Disorders; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Memory Disorders; Methionine; Methionine Adenosyltransferase; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6

2003
Homocysteine and Alzheimer's disease.
    Journal of the American Dietetic Association, 2003, Volume: 103, Issue:3

    Topics: Age Factors; Aged; Alzheimer Disease; Apolipoproteins E; Brain; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Nutrition Policy; Risk Factors; Sex Factors; United States; Vitamin B 12; Vitamin B 6

2003
[Homocysteine and dementia].
    Fortschritte der Neurologie-Psychiatrie, 2003, Volume: 71, Issue:3

    Topics: Alzheimer Disease; Biomarkers; Cerebral Amyloid Angiopathy; Dementia; Dementia, Vascular; Disease Progression; Homocysteine; Humans; Risk Factors

2003
Homocysteine and Alzheimer's disease.
    The Lancet. Neurology, 2003, Volume: 2, Issue:7

    Topics: Alzheimer Disease; Brain; Homocysteine; Hyperhomocysteinemia; Risk Factors

2003
Choosing treatment for Alzheimer's patients and their caregivers.
    Geriatrics, 2003, Volume: 58 Suppl 1

    Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents; Anticonvulsants; Antipsychotic Agents; Caregivers; Cholinesterase Inhibitors; Depression; Ginkgo biloba; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phytotherapy; Plant Extracts; Professional-Family Relations; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Risk Factors; Social Support; Vitamin E

2003
[Public health control of hyperhomocysteinemia and its consequences].
    Orvosi hetilap, 2003, Oct-05, Volume: 144, Issue:40

    Topics: Alzheimer Disease; Canada; Cardiovascular Diseases; Flour; Folic Acid; Food, Fortified; Hematinics; Homocysteine; Humans; Hungary; Hyperhomocysteinemia; Neoplasms; Neural Tube Defects; Primary Prevention; Public Health; Randomized Controlled Trials as Topic; United Kingdom; United States; Vitamin B Complex; Vitamin B Deficiency

2003
Therapeutic strategies for Alzheimer's disease based on new molecular mechanisms.
    Acta neurobiologiae experimentalis, 2003, Volume: 63, Issue:4

    Topics: Alzheimer Disease; Amyloidosis; Cholinesterase Inhibitors; Homocysteine; Humans

2003
[Homocysteine and neuropsychiatric disorders].
    Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2004, Volume: 26, Issue:1

    Topics: Alzheimer Disease; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mental Disorders; Parkinson Disease; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6

2004
[Homocysteine and Alzheimer's disease].
    Sheng li ke xue jin zhan [Progress in physiology], 2004, Volume: 35, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Homocysteine; Humans; Hyperhomocysteinemia

2004
The impact of metabolism on DNA methylation.
    Human molecular genetics, 2005, Apr-15, Volume: 14 Spec No 1

    Topics: Alzheimer Disease; Animals; Arteriosclerosis; DNA Methylation; Folic Acid; Gene Expression Regulation; Glycine N-Methyltransferase; Homocysteine; Humans; Methionine; Methyltransferases; Models, Biological; S-Adenosylmethionine

2005
Biochemical markers and risk factors of Alzheimer's disease.
    Current Alzheimer research, 2005, Volume: 2, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholesterol; Cytokines; Free Radicals; Homocysteine; Humans; Inflammation; Oxidation-Reduction; Oxidative Stress; Phosphorylation; tau Proteins

2005
Ferric cycle activity and Alzheimer disease.
    Current neurovascular research, 2005, Volume: 2, Issue:3

    Topics: Alzheimer Disease; Animals; Brain Chemistry; Cell Cycle; Heme; Homocysteine; Humans; Iron; Models, Biological; Oxidative Stress

2005
Interleukin-1beta and interleukin-6 gene polymorphisms as risk factors for AD: a prospective study.
    Experimental gerontology, 2006, Volume: 41, Issue:1

    Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Dementia; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Interleukin-1; Interleukin-6; Male; Polymorphism, Genetic; Prospective Studies; Risk Factors

2006
The many facets of hyperhomocysteinemia: studies from the Framingham cohorts.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Massachusetts; Middle Aged; Risk Factors; Stroke; Vascular Diseases; Vitamin B 12; Vitamin B 6

2006
Vitamins and minerals 4: overview of folate and the B vitamins.
    Community practitioner : the journal of the Community Practitioners' & Health Visitors' Association, 2006, Volume: 79, Issue:6

    Topics: Alzheimer Disease; Cardiovascular Diseases; Chemoprevention; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neoplasms; Primary Prevention; Risk Factors; Risk Reduction Behavior; Vitamin B 12; Vitamin B 6

2006
Homocysteine and cognition--a historical perspective.
    Journal of Alzheimer's disease : JAD, 2006, Volume: 9, Issue:4

    Topics: Alzheimer Disease; Anemia, Pernicious; Cognition Disorders; Folic Acid Deficiency; History, 19th Century; History, 20th Century; History, 21st Century; Homocysteine; Humans; Vitamin B 12 Deficiency

2006
Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease?
    Journal of Alzheimer's disease : JAD, 2006, Volume: 9, Issue:4

    Topics: Alzheimer Disease; Dementia; Homocysteine; Humans; Risk Assessment; Risk Factors

2006
[Importance of vascular aspects in Alzheimer's disease].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2006, Volume: 43, Issue:4

    Topics: Accidental Falls; Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cause of Death; Cerebral Infarction; Diabetes Complications; Homocysteine; Humans; Hyperlipidemias; Hypertension; Life Style; Pneumonia, Aspiration; Risk Factors

2006
[Immobilization and hip fracture].
    Clinical calcium, 2006, Volume: 16, Issue:12

    Topics: Aged; Alzheimer Disease; Bone Density; Female; Hip Fractures; Homocysteine; Humans; Immobilization; Randomized Controlled Trials as Topic; Vitamin K

2006
Homocysteine and its derivatives as possible modulators of neuronal and non-neuronal cell glutamate receptors in Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2007, Volume: 11, Issue:2

    Topics: Alzheimer Disease; Brain; Calcium; Cell Death; Free Radicals; Homocysteine; Humans; Lymphocytes; Neurons; Oxidative Stress; Reactive Oxygen Species; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate

2007
Diet and Alzheimer's disease.
    Current neurology and neuroscience reports, 2007, Volume: 7, Issue:5

    Topics: Alzheimer Disease; Antioxidants; Brain; Caloric Restriction; Diet Therapy; Dietary Fats; Food, Formulated; Homocysteine; Humans; Oxidative Stress; Randomized Controlled Trials as Topic; Vitamins

2007
Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer's disease--but how and why?
    Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 78, Issue:1

    Topics: Alzheimer Disease; Animals; Arachidonic Acid; Cognition; Dementia; Depression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Folic Acid; Homocysteine; Humans; Inflammation Mediators; Nitric Oxide

2008
Homocysteine and Alzheimer's disease.
    Nutrition reviews, 1999, Volume: 57, Issue:4

    Topics: Aged; Alzheimer Disease; Case-Control Studies; Homocysteine; Humans; Logistic Models; Risk Factors

1999
Number 58: homocysteine and disease.
    Pathology, 2000, Volume: 32, Issue:4

    Topics: Alzheimer Disease; Animals; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Diet; Folic Acid; Homocysteine; Humans; Neural Tube Defects

2000
B vitamins, homocysteine, and neurocognitive function.
    Nutrition reviews, 2001, Volume: 59, Issue:8 Pt 2

    Topics: Aging; Alzheimer Disease; Cognition Disorders; Gastritis, Atrophic; Homocysteine; Humans; Nutritional Status; Vitamin B Deficiency

2001
Nutrition and cognitive impairment in the elderly.
    The British journal of nutrition, 2001, Volume: 86, Issue:3

    Topics: Aged; Aging; Alzheimer Disease; Antioxidants; Avitaminosis; Dementia; Dementia, Vascular; Dietary Supplements; Educational Status; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hypertension; Life Style; Nutritional Physiological Phenomena; Nutritional Status; Risk Factors; Stroke; Vitamin B 12 Deficiency

2001
Homocysteine, vascular dementia and Alzheimer's disease.
    Clinical chemistry and laboratory medicine, 2001, Volume: 39, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Double-Blind Method; Folic Acid; Homocysteine; Humans; Middle Aged; Placebos; Risk Factors; Time Factors; Vitamin B 12; Vitamin B 6

2001
Plasma homocysteine: a new risk factor for Alzheimer's disease?
    The Israel Medical Association journal : IMAJ, 2002, Volume: 4, Issue:3

    Topics: Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12

2002

Trials

17 trial(s) available for homocysteine and Alzheimer Disease

ArticleYear
Clinical efficacy of acupuncture combined with Western medicine in the treatment of mild to moderate Alzheimer disease: A protocol of a randomized controlled trial.
    Medicine, 2022, Sep-30, Volume: 101, Issue:39

    Topics: Activities of Daily Living; Acupuncture Therapy; Alzheimer Disease; Donepezil; Double-Blind Method; Homocysteine; Humans; Prospective Studies; Randomized Controlled Trials as Topic; Single-Blind Method; Superoxide Dismutase; Treatment Outcome

2022
Cross-sectional and prospective associations between homocysteine and a frailty index: A post-hoc analysis of the multidomain Alzheimer's prevention trial (MAPT).
    Experimental gerontology, 2023, Volume: 172

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cross-Sectional Studies; Fatty Acids, Omega-3; Frailty; Homocysteine; Humans

2023
Dietary intakes and biomarker patterns of folate, vitamin B
    Clinical epigenetics, 2019, 10-11, Volume: 11, Issue:1

    Topics: Aged; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Pyrophosphatases; Thioredoxin Reductase 1; Vitamin B 12; Vitamin B 6

2019
Association between malnutrition and hyperhomocysteine in Alzheimer's disease patients and diet intervention of betaine.
    Journal of clinical laboratory analysis, 2017, Volume: 31, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Betaine; Case-Control Studies; Dementia; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Memory; Nerve Tissue Proteins; Risk Factors

2017
Cross-Sectional Associations of Total Plasma Homocysteine with Cortical β-Amyloid Independently and as a Function of Omega 3 Polyunsaturated Fatty Acid Status in Older Adults at Risk of Dementia.
    The journal of nutrition, health & aging, 2017, Volume: 21, Issue:10

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Cross-Sectional Studies; Dementia; Fatty Acids, Omega-3; Female; Homocysteine; Humans; Male; Risk Factors

2017
Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 69, Issue:1

    Topics: Aged; Alzheimer Disease; Cognition; Dietary Supplements; Fatty Acids, Omega-3; Female; Homocysteine; Humans; Male; Treatment Outcome

2019
Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Jun-04, Volume: 110, Issue:23

    Topics: Alzheimer Disease; Bayes Theorem; England; Hippocampus; Homocysteine; Humans; Image Processing, Computer-Assisted; Linear Models; Longitudinal Studies; Magnetic Resonance Imaging; Nerve Degeneration; Temporal Lobe; Vitamin B Complex

2013
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial.
    JAMA, 2008, Oct-15, Volume: 300, Issue:15

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Psychiatric Status Rating Scales; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2008
Treatment of Alzheimer's disease with a cholinesterase inhibitor combined with antioxidants.
    Neuro-degenerative diseases, 2010, Volume: 7, Issue:1-3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Bisphenol A-Glycidyl Methacrylate; Cholinesterase Inhibitors; Cohort Studies; Donepezil; Double-Blind Method; Drug Therapy, Combination; Female; Homocysteine; Humans; Indans; Male; Models, Biological; Oxidative Stress; Piperidines; Polyurethanes; Proteoglycans; Reactive Oxygen Species; Time Factors; Treatment Outcome

2010
Effect of an antioxidant drink on homocysteine levels in Alzheimer's patients.
    Journal of the neurological sciences, 2010, Dec-15, Volume: 299, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cross-Sectional Studies; Double-Blind Method; Female; Flavonoids; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Oxidative Stress; Phenols; Polyphenols; Statistics, Nonparametric; Treatment Outcome; Vitamin B 12

2010
A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people.
    Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Hong Kong; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Patient Dropouts; Vitamin B 12; Vitamin B Complex

2011
Increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with Alzheimer's disease.
    Neurobiology of aging, 2003, Volume: 24, Issue:7

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Arginine; Enzyme Inhibitors; Female; Homocysteine; Humans; Male; Matched-Pair Analysis; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Reference Values; Statistics as Topic

2003
Folic acid supplementation in dementia: a preliminary report.
    Journal of geriatric psychiatry and neurology, 2003, Volume: 16, Issue:3

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Prevalence; Risk Factors

2003
Absence of macrocytic anaemia in Alzheimer's disease.
    Clinical and laboratory haematology, 2004, Volume: 26, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anemia, Macrocytic; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Platelet Count; Sex Factors; Vitamin B 12

2004
Influence of the Glu298Asp polymorphism of NOS3 on age at onset and homocysteine levels in AD patients.
    Neurobiology of aging, 2005, Volume: 26, Issue:6

    Topics: Age Distribution; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Substitution; Female; Genetic Predisposition to Disease; Genetic Testing; Glutamine; Homocysteine; Humans; Italy; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Risk Assessment; Risk Factors; Statistics as Topic

2005
A randomised double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer's disease.
    International journal of geriatric psychiatry, 2008, Volume: 23, Issue:2

    Topics: Aged; Alzheimer Disease; Analysis of Variance; Chi-Square Distribution; Cholinesterase Inhibitors; Dietary Supplements; Donepezil; Double-Blind Method; Female; Folic Acid; Folic Acid Deficiency; Galantamine; Homocysteine; Humans; Indans; Male; Mental Status Schedule; Phenylcarbamates; Piperidines; Placebos; Rivastigmine; Treatment Outcome; Vitamin B Complex; Vitamins

2008
Efficacy of multivitamin supplementation containing vitamins B6 and B12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: a 26-week, randomized, double-blind, placebo-controlled study in Taiwanese patients.
    Clinical therapeutics, 2007, Volume: 29, Issue:10

    Topics: Aged; Alzheimer Disease; Asian People; Cholinesterase Inhibitors; Donepezil; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Indans; Male; Piperidines; Taiwan; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2007

Other Studies

268 other study(ies) available for homocysteine and Alzheimer Disease

ArticleYear
The Link between Exercise and Homocysteine in the Alzheimer's Disease: A Bioinformatic Network Model.
    CNS & neurological disorders drug targets, 2021, Volume: 20, Issue:9

    Topics: Alzheimer Disease; Brain; Cognitive Dysfunction; Computational Biology; Exercise; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress

2021
Association between homocysteine levels and cognitive profile in Alzheimer's Disease.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 94

    Topics: Alzheimer Disease; Cognition; Cross-Sectional Studies; Homocysteine; Humans; Neuropsychological Tests

2021
Ameliorative Effect of Acetyl L-carnitine in Alzheimer's Disease via Downregulating of Homocysteine Levels in Hyperhomocysteinemia Induced Cognitive Deficit in Mouse Model.
    Drug metabolism letters, 2021, Volume: 14, Issue:3

    Topics: Acetylcarnitine; Acetylcholinesterase; Alzheimer Disease; Animals; Cognition; Homocysteine; Hyperhomocysteinemia; Mice; Neuroinflammatory Diseases

2021
Vitamin B12 as a cholinergic system modulator and blood brain barrier integrity restorer in Alzheimer's disease.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2022, Jul-01, Volume: 174

    Topics: Alzheimer Disease; Blood-Brain Barrier; Cholinergic Agents; Folic Acid; Homocysteine; Humans; Receptors, Cholinergic; Vitamin B 12

2022
MiR-483-3p improves learning and memory abilities via XPO1 in Alzheimer's disease.
    Brain and behavior, 2022, Volume: 12, Issue:8

    Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Exportin 1 Protein; Homocysteine; Karyopherins; MicroRNAs; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear

2022
A Retrospective Study on Clinical Assessment of Cognitive Impairment in a Swedish Cohort: Is There Inequality Between Natives and Foreign-Born?
    Journal of Alzheimer's disease : JAD, 2022, Volume: 89, Issue:4

    Topics: Albumins; Alzheimer Disease; Atrophy; Biomarkers; Calcium; Cognitive Dysfunction; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Retrospective Studies; Sweden; Thyrotropin; Vitamin B 12

2022
Diagnostic Values of Advanced Glycation End Products and Homocysteine in Patients with Alzheimer's Disease and Sarcopenia.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: Aged; Alzheimer Disease; Glycation End Products, Advanced; Homocysteine; Humans; ROC Curve; Sarcopenia

2022
Serum Homocysteine, Vitamin B12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia.
    Journal of Alzheimer's disease : JAD, 2022, Volume: 90, Issue:2

    Topics: Alzheimer Disease; Cognitive Dysfunction; Dementia, Vascular; Folic Acid; Frontotemporal Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12

2022
Association of homocysteine-related subcortical brain atrophy with white matter lesion volume and cognition in healthy aging.
    Neurobiology of aging, 2023, Volume: 121

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atrophy; Brain; Cognition; Cognitive Dysfunction; Healthy Aging; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; White Matter

2023
Homocysteine - A predictor for five year-mortality in patients with subjective cognitive decline, mild cognitive impairment and Alzheimer's dementia.
    Experimental gerontology, 2023, Volume: 172

    Topics: Alzheimer Disease; Cognition; Cognitive Dysfunction; Disease Progression; Homocysteine; Humans; Neuropsychological Tests; Retrospective Studies

2023
Diagnostic Value of ATG5, Apo-Lipoprotein B-48, Thyroid Hormones, and Homocysteine in Patients with Alzheimer's Disease.
    Clinical laboratory, 2023, Mar-01, Volume: 69, Issue:3

    Topics: Aged; Alzheimer Disease; Apolipoprotein B-48; Autophagy-Related Protein 5; Folic Acid; Homocysteine; Humans; Middle Aged; Thyroid Hormones; Vitamin B 12

2023
In Situ Fluorescence Imaging Reveals Contribution of Cerebral Hydroxyl Radicals in Hyperhomocysteinemia-Induced Alzheimer-like Dementia.
    Analytical chemistry, 2023, 07-04, Volume: 95, Issue:26

    Topics: Alzheimer Disease; Animals; Homocysteine; Hydroxyl Radical; Hyperhomocysteinemia; Mice; Optical Imaging; Risk Factors

2023
Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes.
    Journal of neuroinflammation, 2023, Sep-01, Volume: 20, Issue:1

    Topics: Alzheimer Disease; Animals; Atorvastatin; Cognition; Cognitive Dysfunction; Dementia, Vascular; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Mice

2023
Neurovascular Correlates of Cobalamin, Folate, and Homocysteine in Dementia.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 96, Issue:3

    Topics: Alzheimer Disease; Brain; Brain Ischemia; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Vitamin B 12

2023
Association of Leukocyte Telomere Length with Mild Cognitive Impairment and Alzheimer's Disease: Role of Folate and Homocysteine.
    Dementia and geriatric cognitive disorders, 2019, Volume: 48, Issue:1-2

    Topics: Aged; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Correlation of Data; Female; Folic Acid; Homocysteine; Humans; Leukocytes; Male; Middle Aged; Telomere Shortening

2019
Plasma Apolipoprotein E Monomer and Dimer Profile and Relevance to Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 71, Issue:4

    Topics: Aged; Alzheimer Disease; Apolipoprotein A-II; Apolipoprotein E3; Apolipoprotein E4; Biomarkers; Cognitive Dysfunction; Female; Homocysteine; Homozygote; Humans; Male; Protein Structure, Quaternary; tau Proteins

2019
The relationship between cognitive impairment and homocysteine in a B12 and folate deficient population in China: A cross-sectional study.
    Medicine, 2019, Volume: 98, Issue:47

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; China; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency

2019
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:3

    Topics: Alzheimer Disease; Animals; Disease Models, Animal; HEK293 Cells; Homocysteine; Humans; Male; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Sulfonamides

2020
Homocysteine Induces Inflammation in Retina and Brain.
    Biomolecules, 2020, 03-03, Volume: 10, Issue:3

    Topics: Alzheimer Disease; Animals; Brain; Diabetic Retinopathy; Homocysteine; Humans; Inflammation; Macular Degeneration; Mice; Mice, Knockout; Retina; U937 Cells

2020
Serum homocysteine and risk of dementia in Japan.
    Journal of neurology, neurosurgery, and psychiatry, 2020, Volume: 91, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Dementia, Vascular; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors

2020
Effects of homocysteine and memantine on oxidative stress related TRP cation channels in
    Journal of receptor and signal transduction research, 2021, Volume: 41, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Calcium; Caspase 3; Caspase 9; Female; Hippocampus; Homocysteine; Male; Memantine; Membrane Potential, Mitochondrial; Mice; Models, Biological; Neurons; Oxidative Stress; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Transient Receptor Potential Channels

2021
Biological and Neuroimaging Markers as Predictors of 5-Year Incident Frailty in Older Adults: A Secondary Analysis of the MAPT Study.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2021, 10-13, Volume: 76, Issue:11

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; C-Reactive Protein; Fatty Acids, Omega-3; Frail Elderly; Frailty; Homocysteine; Humans; Neuroimaging

2021
Levels of Vitamins and Homocysteine in Older Adults with Alzheimer Disease or Mild Cognitive Impairment in Cuba.
    MEDICC review, 2020, Volume: 22, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognitive Dysfunction; Cross-Sectional Studies; Cuba; Homocysteine; Humans; Vitamins

2020
Hyperhomocysteinemia and Dementia Associated With Severe Cortical Atrophy, but No Amyloid Burden.
    Journal of geriatric psychiatry and neurology, 2022, Volume: 35, Issue:1

    Topics: Aged; Alzheimer Disease; Atrophy; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia

2022
Changes in Biothiol Levels Are Closely Associated with Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 82, Issue:2

    Topics: Alzheimer Disease; Animals; Biomarkers; Brain; Cysteine; Down-Regulation; Early Diagnosis; Female; Fluorescent Dyes; Glutathione; Homocysteine; Humans; Male; Mice; Middle Aged; PC12 Cells; Rats; Spectrometry, Fluorescence; Sulfhydryl Compounds; Up-Regulation; Vitamin B 6; Vitamin B Complex

2021
Relationship of Homocysteine Plasma Levels with Mild Cognitive Impairment, Alzheimer's Disease, Vascular Dementia, Psychobehavioral, and Functional Complications.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 82, Issue:1

    Topics: Activities of Daily Living; Aged; Alzheimer Disease; Brief Psychiatric Rating Scale; Cognitive Dysfunction; Dementia, Vascular; Female; Homocysteine; Humans; Interviews as Topic; Male

2021
Homocysteine fibrillar assemblies display cross-talk with Alzheimer's disease β-amyloid polypeptide.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 06-15, Volume: 118, Issue:24

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Brain; Cell Death; Cell Line, Tumor; Disease Models, Animal; Homocysteine; Humans; Ion Mobility Spectrometry; Kinetics; Mice, Transgenic; Models, Biological; Polyphenols; Saccharomyces cerevisiae

2021
Hypohomocysteinemia may increases the risk of dementia and Alzheimer's disease: A nationwide population-based prospective cohort study.
    Clinical nutrition (Edinburgh, Scotland), 2021, Volume: 40, Issue:7

    Topics: Aged; Alzheimer Disease; Dementia; Dietary Supplements; Female; Homocysteine; Humans; Independent Living; Male; Middle Aged; Proportional Hazards Models; Prospective Studies

2021
Direct Quantification and Visualization of Homocysteine, Cysteine, and Glutathione in Alzheimer's and Parkinson's Disease Model Tissues.
    Analytical chemistry, 2021, 07-20, Volume: 93, Issue:28

    Topics: Alzheimer Disease; Animals; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Humans; Mice; Parkinson Disease

2021
Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.
    Scientific reports, 2017, 04-06, Volume: 7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Diet; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hydroxyurea; Inflammation; Lipoxygenase; Male; Mice, Transgenic; Phenotype; Phosphorylation; Synapses; tau Proteins; Up-Regulation; Vitamin B Complex; Vitamin B Deficiency

2017
Oxidative Stress Markers and Metal Ions are Correlated With Cognitive Function in Alzheimer's Disease.
    American journal of Alzheimer's disease and other dementias, 2017, Volume: 32, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; C-Reactive Protein; Cations; Ceruloplasmin; Copper; Female; Homocysteine; Humans; Iron; Male; Oxidative Stress; Severity of Illness Index; Uric Acid; Zinc

2017
One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond.
    Alzheimer's research & therapy, 2017, Jun-17, Volume: 9, Issue:1

    Topics: Aged; Alzheimer Disease; Biomarkers; Carbon; Carbon Compounds, Inorganic; Cognition Disorders; Comorbidity; Female; Homocysteine; Humans; Male; Prevalence; Risk Factors; Switzerland

2017
Combined assessment of DYRK1A, BDNF and homocysteine levels as diagnostic marker for Alzheimer's disease.
    Translational psychiatry, 2017, 06-20, Volume: 7, Issue:6

    Topics: Aged; Alzheimer Disease; Animals; Antibodies, Monoclonal; Biomarkers; Brain-Derived Neurotrophic Factor; Dyrk Kinases; Female; Homocysteine; Humans; Male; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; ROC Curve

2017
Plasma Homocysteine and Serum Folate and Vitamin B
    Nutrients, 2017, Jul-08, Volume: 9, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12

2017
Effects of Homocysteine on white matter diffusion parameters in Alzheimer's disease.
    BMC neurology, 2017, Oct-06, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Algorithms; Alzheimer Disease; Anisotropy; Brain; Cross-Sectional Studies; Diffusion Tensor Imaging; Female; Homocysteine; Humans; Male; Neuroimaging; White Matter

2017
Homocysteine concentrations in the cognitive progression of Alzheimer's disease.
    Experimental gerontology, 2017, 12-01, Volume: 99

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition; Disease Progression; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Mental Status and Dementia Tests; Neuropsychological Tests; Nutrition Assessment; Nutritional Status; Surveys and Questionnaires; Time Factors; Up-Regulation; Vitamin B 12

2017
Genetic influence of plasma homocysteine on Alzheimer's disease.
    Neurobiology of aging, 2018, Volume: 62

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Atrophy; Cognitive Dysfunction; Female; Genetic Association Studies; Genetic Predisposition to Disease; Gray Matter; Homocysteine; Humans; Male; Multifactorial Inheritance; Risk Factors; tau Proteins; White People

2018
Low-grade systemic inflammation is associated with functional disability in elderly people affected by dementia.
    GeroScience, 2018, Volume: 40, Issue:1

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; C-Reactive Protein; Case-Control Studies; Cognitive Dysfunction; Dementia; Disability Evaluation; Disease Progression; Female; Geriatric Assessment; Homocysteine; Humans; Inflammation; Italy; Male; Reference Values; Retrospective Studies

2018
Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.
    International journal of molecular sciences, 2018, Mar-17, Volume: 19, Issue:3

    Topics: Alzheimer Disease; Animals; Brain; Cell Line, Tumor; Cyclin-Dependent Kinase 5; Disease Models, Animal; Glycogen Synthase Kinase 3; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Transgenic; Neurofibrillary Tangles; Phosphorylation; Protein Aggregation, Pathological; Protein Phosphatase 2; tau Proteins; Tauopathies

2018
Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 63, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Cognition Disorders; Disease Models, Animal; Homocysteine; Male; Maze Learning; Moringa oleifera; Nerve Tissue Proteins; Neurons; Oxidative Stress; Peptide Fragments; Phosphorylation; Plant Extracts; Rats; Rats, Sprague-Dawley; Silver Staining; tau Proteins

2018
Elevated levels of brain homocysteine directly modulate the pathological phenotype of a mouse model of tauopathy.
    Molecular psychiatry, 2019, Volume: 24, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Arachidonate 5-Lipoxygenase; Brain; Disease Models, Animal; Female; Homocysteine; Male; Mice; Mice, Transgenic; Phenotype; Phosphorylation; Synapses; tau Proteins; Tauopathies

2019
Interplay between the APOE Genotype and Possible Plasma Biomarkers in Alzheimer's Disease.
    Current Alzheimer research, 2018, Volume: 15, Issue:10

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Biomarkers; Female; Genotype; Homocysteine; Humans; Hydrocortisone; Male; Melatonin; Middle Aged; Prolactin

2018
Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 64, Issue:1

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Female; Folic Acid; Glycogen Synthase Kinase 3 beta; Homocysteine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Transgenic; Mutation; Phosphorylation

2018
Association of Induced Hyperhomocysteinemia with Alzheimer's Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury.
    Neurochemical research, 2018, Volume: 43, Issue:9

    Topics: Alzheimer Disease; Animals; Cerebral Cortex; Homocysteine; Hyperhomocysteinemia; Male; Nerve Degeneration; Rats; Rats, Wistar; Reperfusion Injury

2018
Small Vessel Cerebrovascular Pathology Identified by Magnetic Resonance Imaging Is Prevalent in Alzheimer's Disease and Mild Cognitive Impairment: A Potential Target for Intervention.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 65, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain Infarction; Cerebrovascular Disorders; Cognitive Dysfunction; Cross-Sectional Studies; Disease Progression; Female; Homocysteine; Humans; Image Processing, Computer-Assisted; Independent Living; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Risk Factors

2018
Folate/Vitamin B Alleviates Hyperhomocysteinemia-Induced Alzheimer-Like Pathologies in Rat Retina.
    Neuroscience bulletin, 2019, Volume: 35, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Dietary Supplements; Disease Models, Animal; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Rats, Sprague-Dawley; Retina; Retinal Vessels; tau Proteins; Vitamin B 12

2019
Genetic influence of plasma homocysteine on Alzheimer's disease.
    Neurobiology of aging, 2019, Volume: 76

    Topics: Alzheimer Disease; Cognitive Dysfunction; Genetic Association Studies; Homocysteine; Humans

2019
Methanolic extract of
    Aging, 2018, 11-12, Volume: 10, Issue:11

    Topics: Alzheimer Disease; Animals; Homocysteine; Hyperhomocysteinemia; Male; Memory Disorders; Methanol; Neurons; Oxidative Stress; Phosphorus Compounds; Phosphotransferases; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Tamaricaceae; tau Proteins

2018
Associations of lifestyle and vascular risk factors with Alzheimer's brain biomarker changes during middle age: a 3-year longitudinal study in the broader New York City area.
    BMJ open, 2018, 11-25, Volume: 8, Issue:11

    Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Brain; Brain Chemistry; Diet; Glucose; Homocysteine; Humans; Life Style; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; New York City; Positron-Emission Tomography; Prospective Studies; Risk Factors; Vascular Diseases

2018
Maternal choline supplementation ameliorates Alzheimer's disease pathology by reducing brain homocysteine levels across multiple generations.
    Molecular psychiatry, 2020, Volume: 25, Issue:10

    Topics: Alzheimer Disease; Animals; Brain; Choline; Dietary Supplements; Disease Models, Animal; Female; Homocysteine; Male; Mice; Mice, Transgenic

2020
A validated LC-MS/MS method for the determination of homocysteic acid in biological samples.
    Journal of pharmaceutical and biomedical analysis, 2019, Sep-10, Volume: 174

    Topics: Algorithms; Alzheimer Disease; Body Fluids; Calibration; Chromatography, Liquid; Female; Healthy Volunteers; Homocysteine; Humans; Male; Oxygen; Quality Control; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry

2019
Biomarkers of vascular risk, systemic inflammation, and microvascular pathology and neuropsychiatric symptoms in Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2013, Volume: 35, Issue:2

    Topics: Aged; Alzheimer Disease; Biomarkers; C-Reactive Protein; Capillaries; Cerebrovascular Disorders; Cholesterol; Cohort Studies; Cytokines; Data Interpretation, Statistical; Educational Status; Female; Homocysteine; Humans; Inflammation; Male; Neuropsychological Tests; Predictive Value of Tests; Psychiatric Status Rating Scales; Risk Assessment; Sex Characteristics; Texas; Triglycerides

2013
Pro-inflammatory cytokines IL-1β and TNF-α are not associated with plasma homocysteine concentration in Alzheimer's disease.
    Current Alzheimer research, 2013, Volume: 10, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chi-Square Distribution; Female; Homocysteine; Humans; Interleukin-1beta; Logistic Models; Male; Tumor Necrosis Factor-alpha

2013
Impact of homocysteine on cortical perfusion and cognitive decline in mild Alzheimer's dementia.
    European journal of neurology, 2013, Volume: 20, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cerebrovascular Circulation; Cognition Disorders; Disease Progression; Female; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Perfusion; Risk Factors; Tomography, Emission-Computed, Single-Photon

2013
High cortisol and low folate are the only routine blood tests predicting probable Alzheimer's disease after age 75-results of the Vienna Transdanube Aging Study.
    Journal of the American Geriatrics Society, 2013, Volume: 61, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Apolipoprotein E4; Austria; Cohort Studies; Confidence Intervals; Diagnostic Tests, Routine; Female; Folic Acid; Hematologic Tests; Homocysteine; Humans; Hydrocortisone; Longitudinal Studies; Male; Odds Ratio; Prognosis; Risk Factors

2013
Association of methylenetetrahydrofolate reductase polymorphisms with susceptibility to Alzheimer's disease.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:9

    Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Mutation, Missense; Polymorphism, Genetic; Risk Factors

2013
Homocysteine levels and cognitive function scores measured with MMSE and BCAT of middle-aged and elderly subjects in Tianjin City.
    The journal of nutrition, health & aging, 2013, Volume: 17, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; China; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intelligence Tests; Linear Models; Male; Middle Aged; Neuropsychological Tests; Prevalence; Sex Factors; Surveys and Questionnaires

2013
[The clinical studies of hyperhomocysteinemia and Alzheimer's disease].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2013, Volume: 29, Issue:2

    Topics: Alzheimer Disease; Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia

2013
Hydroxysafflor yellow A ameliorates homocysteine-induced Alzheimer-like pathologic dysfunction and memory/synaptic disorder.
    Rejuvenation research, 2013, Volume: 16, Issue:6

    Topics: Alzheimer Disease; Animals; Blotting, Western; Chalcone; Enzyme-Linked Immunosorbent Assay; Homocysteine; Male; Maze Learning; Memory Disorders; Quinones; Rats; Rats, Sprague-Dawley; Synapses

2013
Alzheimer's disease treated patients showed different patterns for oxidative stress and inflammation markers.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Arginine; Biomarkers; Case-Control Studies; Endothelium, Vascular; Female; Glutathione; Homocysteine; Humans; Inflammation; Interleukin-6; Male; Oxidative Stress; Protein Carbonylation; Tumor Necrosis Factor-alpha

2013
Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study.
    Brain : a journal of neurology, 2013, Volume: 136, Issue:Pt 9

    Topics: Aged, 80 and over; alpha-Synuclein; Alzheimer Disease; Apolipoproteins E; Cerebral Amyloid Angiopathy; Cerebrovascular Disorders; Community Health Planning; Diagnosis; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neurofibrillary Tangles; Plaque, Amyloid

2013
Serum folate, homocysteine, brain atrophy, and auto-CM system: The Treviso Dementia (TREDEM) study.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 38, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Atrophy; Brain; Brain Mapping; Disability Evaluation; Female; Folic Acid; Homocysteine; Humans; Italy; Male; Middle Aged; Neuroimaging; Neuropsychological Tests; Outpatients; Retrospective Studies

2014
The MTHFR 677T allele may influence the severity and biochemical risk factors of Alzheimer's disease in an Egyptian population.
    Disease markers, 2013, Volume: 35, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholesterol; Egypt; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12

2013
Oxidative balance, homocysteine, and uric acid levels in older patients with Late Onset Alzheimer's Disease or Vascular Dementia.
    Journal of the neurological sciences, 2014, Feb-15, Volume: 337, Issue:1-2

    Topics: Advanced Oxidation Protein Products; Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cognitive Dysfunction; Dementia, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Hydrogen Peroxide; Male; Neuropsychological Tests; Oxidative Stress; Retrospective Studies; Tomography, X-Ray Computed; Uric Acid

2014
Impaired renal function and biomarkers of vascular disease in Alzheimer's disease.
    Current Alzheimer research, 2014, Volume: 11, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Biomarkers; Case-Control Studies; Creatinine; Female; Glomerular Filtration Rate; Homocysteine; Humans; Kidney Diseases; Male; Mental Status Schedule; Multivariate Analysis; Risk Factors; Vascular Diseases

2014
Association of homocysteine with hippocampal volume independent of cerebral amyloid and vascular burden.
    Neurobiology of aging, 2014, Volume: 35, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cognition Disorders; Cognitive Dysfunction; Female; Hippocampus; Homocysteine; Humans; Linear Models; Male; Middle Aged; Risk Factors

2014
The impact of APOE status on relationship of biomarkers of vascular risk and systemic inflammation to neuropsychiatric symptoms in Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 40, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Biomarkers; Cholesterol; Cytokines; Female; Homocysteine; Humans; Inflammation; Male; Psychiatric Status Rating Scales; Regression, Psychology; Sex Factors; Triglycerides

2014
Plasma homocysteine in Alzheimer's disease with or without co-morbid depressive symptoms.
    Neuro endocrinology letters, 2014, Volume: 35, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Comorbidity; Depressive Disorder; Female; Homocysteine; Humans; Male; Middle Aged; Severity of Illness Index

2014
Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles.
    Annals of neurology, 2014, Volume: 75, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cell Line, Tumor; Cognition Disorders; Diet; Disease Models, Animal; Homocysteine; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neuroblastoma; Neurofibrillary Tangles; Plaque, Amyloid; Presenilin-1; Signal Transduction; tau Proteins

2014
Hyperhomocysteinemia is a risk factor for Alzheimer's disease in an Algerian population.
    Archives of medical research, 2014, Volume: 45, Issue:3

    Topics: Aged; Aged, 80 and over; Algeria; Alzheimer Disease; Case-Control Studies; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Risk Factors; Thyrotropin; Uric Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2014
Correlation between behavioural and psychological symptoms of Alzheimer type dementia and plasma homocysteine concentration.
    BioMed research international, 2014, Volume: 2014

    Topics: Adult; Aged; Alzheimer Disease; Female; Homocysteine; Humans; Male; Middle Aged; Severity of Illness Index

2014
High levels of homocysteine results in cerebral amyloid angiopathy in mice.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 43, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animal Feed; Animals; Brain; Cerebral Amyloid Angiopathy; Diet; Disease Models, Animal; Female; Homocysteine; Hyperhomocysteinemia; Male; Mice, Transgenic; Random Allocation

2015
Fatty acid status and its relationship to cognitive decline and homocysteine levels in the elderly.
    Nutrients, 2014, Sep-12, Volume: 6, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cognition; Cognition Disorders; Dementia; Diet; Docosahexaenoic Acids; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Geriatric Assessment; Homocysteine; Humans; Lipids; Male; Memory; Nutritional Status; Risk Factors

2014
There are no differences in IL-6, CRP and homocystein concentrations between women whose mothers had AD and women whose mothers did not have AD.
    Psychiatry research, 2014, Dec-30, Volume: 220, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Brain; C-Reactive Protein; Cross-Sectional Studies; Female; Homocysteine; Humans; Interleukin-6; Middle Aged; Mothers

2014
Fatty acids rehabilitated long-term neurodegenerative: like symptoms in olfactory bulbectomized rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:5

    Topics: Alzheimer Disease; Animals; Avoidance Learning; Body Temperature Regulation; Brain; Cholesterol; Cytokines; Disease Models, Animal; Eating; Fatty Acids; Homocysteine; Iron; Male; Maze Learning; Motor Activity; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Olfactory Bulb; Rats, Long-Evans; Synaptosomes

2015
The relationship between cholesterol and cognitive function is homocysteine-dependent.
    Clinical interventions in aging, 2014, Volume: 9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; China; Cholesterol; Cross-Sectional Studies; Dementia; Female; Homocysteine; Humans; Hypercholesterolemia; Lipoproteins, HDL; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Psychometrics; Risk Factors; Statistics as Topic; Triglycerides

2014
Higher homocysteine associated with thinner cortical gray matter in 803 participants from the Alzheimer's Disease Neuroimaging Initiative.
    Neurobiology of aging, 2015, Volume: 36 Suppl 1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atrophy; Biomarkers; Female; Folic Acid; Gray Matter; Homocysteine; Humans; Life Style; Magnetic Resonance Imaging; Male; Neuroimaging; Risk Factors; Vitamin B Complex

2015
Association between intake of B vitamins and cognitive function in elderly Koreans with cognitive impairment.
    Nutrition journal, 2014, Dec-17, Volume: 13, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Republic of Korea; Vitamin B 12; Vitamin B Complex

2014
Associations between Alzheimer's disease and blood homocysteine, vitamin B12, and folate: a case-control study.
    Current Alzheimer research, 2015, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Chromatography, High Pressure Liquid; Cognition Disorders; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Psychiatric Status Rating Scales; Retrospective Studies; Surveys and Questionnaires; Vitamin B 12

2015
Plasma thiols levels in Alzheimer's disease mice under diet-induced hyperhomocysteinemia: effect of S-adenosylmethionine and superoxide-dismutase supplementation.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 44, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Chromatography; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; S-Adenosylmethionine; Sulfhydryl Compounds; Superoxide Dismutase

2015
Apolipoprotein E genotype modulates effects of vitamin B12 and homocysteine on grey matter volume in Alzheimer's disease.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2016, Volume: 16, Issue:1

    Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Case-Control Studies; Female; Genotype; Gray Matter; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Republic of Korea; Vitamin B 12

2016
Hydrogen Sulfide Ameliorates Homocysteine-Induced Alzheimer's Disease-Like Pathology, Blood-Brain Barrier Disruption, and Synaptic Disorder.
    Molecular neurobiology, 2016, Volume: 53, Issue:4

    Topics: Alzheimer Disease; Animals; Antigens, CD; Avoidance Learning; Blood-Brain Barrier; Cadherins; Cerebrovascular Circulation; Claudin-5; Cystathionine beta-Synthase; Dizocilpine Maleate; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Homocysteine; Hydrogen Sulfide; Intercellular Adhesion Molecule-1; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Memory; Mice, Inbred C57BL; Microtubule-Associated Proteins; Microvessels; Nerve Tissue Proteins; Permeability; RNA, Messenger; Synapses

2016
Methylation analysis of multiple genes in blood DNA of Alzheimer's disease and healthy individuals.
    Neuroscience letters, 2015, Jul-23, Volume: 600

    Topics: 5' Untranslated Regions; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid Precursor Protein Secretases; Apolipoprotein E4; Aspartic Acid Endopeptidases; Biomarkers; Case-Control Studies; CpG Islands; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Presenilin-1; Promoter Regions, Genetic; Sex Factors; Vitamin B 12

2015
Increased levels of plasma amyloid-beta are related to cortical thinning and cognitive decline in cognitively normal elderly subjects.
    Neurobiology of aging, 2015, Volume: 36, Issue:10

    Topics: Aged; Aging; Alzheimer Disease; Amyloid beta-Peptides; Cerebral Cortex; Cognition; Cognition Disorders; Female; Homocysteine; Humans; Male; Peptide Fragments; Risk Factors

2015
Buccal Cytome Biomarkers and Their Association with Plasma Folate, Vitamin B12 and Homocysteine in Alzheimer's Disease.
    Journal of nutrigenetics and nutrigenomics, 2015, Volume: 8, Issue:2

    Topics: Aged; Alzheimer Disease; Biomarkers; Cheek; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12

2015
Effects of an antioxidant beverage on biomarkers of oxidative stress in Alzheimer's patients.
    European journal of nutrition, 2016, Volume: 55, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Aged, 80 and over; Alanine Transaminase; Alzheimer Disease; Antioxidants; Aspartate Aminotransferases; Beverages; Biomarkers; Body Mass Index; C-Reactive Protein; Case-Control Studies; Deoxyguanosine; Female; Ferritins; Folic Acid; Glutathione Peroxidase; Homocysteine; Humans; Isoprostanes; Lipids; Male; Malus; Oxidative Stress; Plant Extracts; Protein Carbonylation; Superoxide Dismutase; Tea; Vitamin B 12

2016
Homocysteine, antioxidant vitamins and lipids as biomarkers of neurodegeneration in Alzheimer's disease versus non-Alzheimer's dementia.
    Annals of agricultural and environmental medicine : AAEM, 2016, Volume: 23, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Biomarkers; Cognition Disorders; Dementia; Female; Homocysteine; Humans; Lipids; Male; Middle Aged; Vitamins

2016
Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study.
    JAMA psychiatry, 2016, 06-01, Volume: 73, Issue:6

    Topics: Aged; Alzheimer Disease; Amino Acids, Sulfur; Atrophy; Brain; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Risk Factors; Statistics as Topic; Sweden; Vitamin B 12; White Matter

2016
A multipronged, nutritional-based strategy for managing Alzheimer's disease.
    Medical hypotheses, 2016, Volume: 91

    Topics: Aged; Albumins; Aluminum; Alzheimer Disease; Amyloid beta-Peptides; Animals; Atrophy; Blood-Brain Barrier; Brain; Carbohydrate Metabolism; Diabetes Mellitus; Dietary Supplements; Gray Matter; Homocysteine; Humans; Learning; Magnesium; Magnesium Deficiency; Memory; Middle Aged; Models, Theoretical; N-Methylaspartate; Nutritional Sciences; Plasma Exchange; Rats; Silicic Acid; Vitamin B Complex

2016
Conversion from MCI to AD in patients with the APOE ε4 genotype: Prediction by plasma HCY and serum BDNF.
    Neuroscience letters, 2016, 07-28, Volume: 626

    Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Biomarkers; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Disease Progression; Female; Genotype; Homocysteine; Humans; Male; Sensitivity and Specificity

2016
The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration.
    Neuroreport, 2016, 08-17, Volume: 27, Issue:12

    Topics: Aged; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2)

2016
Artificial Neural Networks Link One-Carbon Metabolism to Gene-Promoter Methylation in Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2016, 07-01, Volume: 53, Issue:4

    Topics: Age Factors; Aged; Alzheimer Disease; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Biomarkers; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neural Networks, Computer; Presenilin-1; Promoter Regions, Genetic; Sex Factors; Vitamin B 12

2016
The involvement of homocysteine in stress-induced Aβ precursor protein misprocessing and related cognitive decline in rats.
    Cell stress & chaperones, 2016, Volume: 21, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Hippocampus; Homocysteine; Male; Protein Processing, Post-Translational; Rats, Sprague-Dawley; Stress, Psychological

2016
Targeting therapy for homocysteic acid in the blood represents a potential recovery treatment for cognition in Alzheimer's disease patients.
    Aging, 2016, 09-14, Volume: 8, Issue:9

    Topics: Alzheimer Disease; Animals; Antibodies; Cognition Disorders; Disease Models, Animal; Homocysteine; Mice

2016
Testing for homocysteine in clinical practice.
    Nutrition and health, 2017, Volume: 23, Issue:1

    Topics: Alzheimer Disease; Blood Chemical Analysis; Cardiovascular Diseases; Cognition Disorders; Delivery of Health Care; Homocysteine; Humans; Hyperhomocysteinemia; Practice Patterns, Physicians'

2017
Clinical and Environmental Correlates of Serum BDNF: A Descriptive Study with Plausible Implications for AD Research.
    Current Alzheimer research, 2017, Volume: 14, Issue:7

    Topics: Adult; Alzheimer Disease; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Cohort Studies; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Linear Models; Male; Middle Aged; Psychiatric Status Rating Scales; Tumor Necrosis Factor-alpha

2017
Malondialdehyde, carbonyl proteins and albumin-disulphide as useful oxidative markers in mild cognitive impairment and Alzheimer's disease.
    Free radical research, 2008, Volume: 42, Issue:7

    Topics: Aged; Alzheimer Disease; Biomarkers; Case-Control Studies; Cognition Disorders; Disulfides; Female; Folic Acid; Homocysteine; Humans; Male; Malondialdehyde; Middle Aged; Neopterin; Nerve Degeneration; Oxidative Stress; Protein Carbonylation; Serum Albumin; Severity of Illness Index; Vitamin B 12

2008
Folate deprivation, the methionine cycle, and Alzheimer's disease.
    Vitamins and hormones, 2008, Volume: 79

    Topics: Alzheimer Disease; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Methionine

2008
C-reactive protein: vascular risk marker in elderly patients with mental illness.
    Dementia and geriatric cognitive disorders, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; C-Reactive Protein; Cerebrovascular Disorders; Cognition Disorders; Cystatin C; Depression; Female; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Risk Factors

2008
B vitamins for prevention of cognitive decline: insufficient evidence to justify treatment.
    JAMA, 2008, Oct-15, Volume: 300, Issue:15

    Topics: Alzheimer Disease; Cognition; Cognition Disorders; Dietary Supplements; Homocysteine; Humans; Vitamin B Complex

2008
Cognitive performance and plasma levels of homocysteine, vitamin B12, folate and lipids in patients with Alzheimer disease.
    Dementia and geriatric cognitive disorders, 2008, Volume: 26, Issue:4

    Topics: Aged; Alzheimer Disease; Cholesterol, HDL; Cholesterol, LDL; Cognition; Cross-Sectional Studies; Databases, Factual; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Psychomotor Performance; Sex Characteristics; Triglycerides; Vitamin B 12

2008
Higher folate intake is related to lower risk of Alzheimer's disease in the elderly.
    The journal of nutrition, health & aging, 2008, Volume: 12, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Male; Nutrition Assessment; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2008
[Plasma levels of endogenous hydrogen sulfide and homocysteine in patients with Alzheimer's disease and vascular dementia and the significance thereof].
    Zhonghua yi xue za zhi, 2008, Aug-19, Volume: 88, Issue:32

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Female; Homocysteine; Humans; Hydrogen Sulfide; Male; Middle Aged; Psychiatric Status Rating Scales

2008
Association between genetic and environmental factors and the risk of Alzheimer's disease.
    Folia neuropathologica, 2008, Volume: 46, Issue:4

    Topics: Alzheimer Disease; Apolipoproteins E; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hypercholesterolemia; Methylenetetrahydrofolate Reductase (NADPH2); Nitric Oxide Synthase Type III; Risk Factors; Vitamin B 12

2008
Brain MRI, apoliprotein E genotype, and plasma homocysteine in American Indian Alzheimer disease patients and Indian controls.
    Current Alzheimer research, 2009, Volume: 6, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Brain; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Indians, North American; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Polymorphism, Genetic

2009
Serum homocysteine: interplay with other circulating and genetic factors in association to Alzheimer's type dementia.
    Clinical biochemistry, 2009, Volume: 42, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; C-Reactive Protein; Case-Control Studies; Estradiol; Female; Homocysteine; Humans; Male; Middle Aged; Mutation; Polymorphism, Restriction Fragment Length; Testosterone; Tetrahydrofolates; Urea; Uric Acid

2009
Interaction between interleukin-8 and methylenetetrahydrofolate reductase genes modulates Alzheimer's disease risk.
    Dementia and geriatric cognitive disorders, 2009, Volume: 27, Issue:3

    Topics: Aged; Alleles; Alzheimer Disease; China; Female; Gene Frequency; Genotype; Homocysteine; Humans; Interleukin-8; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment

2009
Paraoxonase activity and dementia.
    Journal of the neurological sciences, 2009, Aug-15, Volume: 283, Issue:1-2

    Topics: Aged; Alzheimer Disease; Aryldialkylphosphatase; Cholesterol; Cholesterol, HDL; Cognition Disorders; Dementia; Dementia, Vascular; Female; Homocysteine; Humans; Immunoenzyme Techniques; Male; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Sequence Analysis, DNA; Spectrophotometry; Triglycerides

2009
Cerebral white matter lesions in patients with dementia - from MCI to severe Alzheimer's disease.
    Journal of the neurological sciences, 2009, Aug-15, Volume: 283, Issue:1-2

    Topics: Aged; Aging; Alzheimer Disease; Brain; Cognition Disorders; Disease Progression; Female; Homocysteine; Humans; Hypertension; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated

2009
High-dose B vitamin supplements and Alzheimer disease.
    JAMA, 2009, Mar-11, Volume: 301, Issue:10

    Topics: Alzheimer Disease; Cognition Disorders; Dietary Supplements; Homocysteine; Humans; Reference Values; Vitamin B Complex

2009
High-dose B vitamin supplements and Alzheimer disease.
    JAMA, 2009, Mar-11, Volume: 301, Issue:10

    Topics: Alzheimer Disease; Blood-Brain Barrier; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Vitamin B Complex

2009
Homocysteine and holo-transcobalamin and the risk of dementia and Alzheimers disease: a prospective study.
    European journal of neurology, 2009, Volume: 16, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Community Health Planning; Dementia; Female; Homocysteine; Humans; Male; Models, Anatomic; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Transcobalamins

2009
Homocysteine as a predictor of cognitive decline in Alzheimer's disease.
    International journal of geriatric psychiatry, 2010, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Cohort Studies; Female; Homocysteine; Humans; Longitudinal Studies; Male; Neuropsychological Tests; Nonlinear Dynamics; Predictive Value of Tests

2010
Relationship between genetic polymorphism, serum folate and homocysteine in Alzheimer's disease.
    Asia-Pacific journal of public health, 2008, Volume: 20 Suppl

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide

2008
Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2009, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; Case-Control Studies; Female; Genotype; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Neuropsychological Tests; Peptide Fragments; S-Adenosylmethionine; tau Proteins; Tetrahydrofolates; Young Adult

2009
[Does acidosis in brain play a role in Alzheimer's disease?].
    Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater, 2009, Volume: 23, Issue:3

    Topics: Acidosis; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Brain; Brain Ischemia; Cell Death; Cerebral Arteries; Cholesterol; Homocysteine; Humans; Inflammation; Lactic Acid; Neurons; Risk Factors; tau Proteins

2009
Sialic acid, homocysteine and CRP: potential markers for dementia.
    Neuroscience letters, 2009, Nov-20, Volume: 465, Issue:3

    Topics: Aged; Alzheimer Disease; Biomarkers; C-Reactive Protein; Dementia; Female; Homocysteine; Humans; Male; N-Acetylneuraminic Acid; Reproducibility of Results; Sensitivity and Specificity

2009
A prospective study on the development of Alzheimer's disease with regard to thyroid-stimulating hormone and homocysteine.
    Dementia and geriatric cognitive disorders, 2009, Volume: 28, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Cohort Studies; Creatinine; Disease Progression; Female; Homocysteine; Humans; Male; Neuropsychological Tests; Prospective Studies; Risk Assessment; Socioeconomic Factors; Sweden; Thyrotropin

2009
Elevated serum homocysteine level is not associated with serum C-reactive protein in patients with probable Alzheimer's disease.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:12

    Topics: Aged; Alzheimer Disease; Blood Pressure; Body Mass Index; C-Reactive Protein; Cognition Disorders; Female; Homocysteine; Humans; Male; Neuropsychological Tests; Sex Factors

2009
Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease.
    Current Alzheimer research, 2010, Volume: 7, Issue:2

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Brain; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Down-Regulation; Female; Food, Formulated; Glycogen Synthase Kinase 3; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Transgenic; Plaque, Amyloid; Serine

2010
Homocysteine may contribute to pathogenesis of RNA damage in brains with Alzheimer's disease.
    Neuro-degenerative diseases, 2009, Volume: 6, Issue:5-6

    Topics: Aged; Alzheimer Disease; Brain; Case-Control Studies; Female; Guanosine; Homocysteine; Humans; Male; Middle Aged; RNA; Statistics as Topic

2009
Homocystamides promote free-radical and oxidative damage to proteins.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-12, Volume: 107, Issue:2

    Topics: Alzheimer Disease; Cardiovascular Diseases; Congenital Abnormalities; Free Radicals; Homocysteine; Humans; Hydrogen Bonding; Kinetics; Lysine; Osteoporosis; Oxidative Stress; Protein Processing, Post-Translational; Renal Insufficiency; Serum Albumin

2010
Treatment of Alzheimer's disease with anti-homocysteic acid antibody in 3xTg-AD male mice.
    PloS one, 2010, Jan-20, Volume: 5, Issue:1

    Topics: Alzheimer Disease; Animals; Antibodies; Homocysteine; Immunohistochemistry; Immunotherapy; Male; Maze Learning; Mice; Mice, Transgenic

2010
Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 19, Issue:3

    Topics: Alzheimer Disease; Animals; Apoptosis; Caspase 3; Cerebral Cortex; DNA Fragmentation; Drugs, Chinese Herbal; Homocysteine; Hydro-Lyases; Neurons; Neuroprotective Agents; Phosphorylation; Phytotherapy; Rats; Rats, Sprague-Dawley; tau Proteins

2010
Oxidative LDL modification is increased in vascular dementia and is inversely associated with cognitive performance.
    Free radical research, 2010, Volume: 44, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Cognition Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Oxidation-Reduction

2010
Protective effect of isoflavones against homocysteine-mediated neuronal degeneration in SH-SY5Y cells.
    Amino acids, 2010, Volume: 39, Issue:3

    Topics: Alzheimer Disease; Apoptosis; Cell Line, Tumor; Endoplasmic Reticulum; Homocysteine; Humans; Isoflavones; Nerve Degeneration; Neurons; Protective Agents; S-Adenosylhomocysteine

2010
Fasting and post-methionine homocysteine levels in Alzheimers disease and vascular dementia.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2009, Volume: 79, Issue:3

    Topics: Aged; Alzheimer Disease; Case-Control Studies; Cohort Studies; Dementia, Vascular; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Statistics, Nonparametric; Vitamin B 12

2009
Increased tissue factor pathway inhibitor and homocysteine in Alzheimer's disease.
    Neurobiology of aging, 2012, Volume: 33, Issue:2

    Topics: Aged; Alzheimer Disease; Biomarkers; Female; Homocysteine; Humans; Lipoproteins; Male; Reproducibility of Results; Sensitivity and Specificity

2012
S-adenosylhomocysteine: a better marker of the development of Alzheimer's disease than homocysteine?
    Journal of Alzheimer's disease : JAD, 2010, Volume: 21, Issue:1

    Topics: Alzheimer Disease; Animals; Biomarkers; Homocysteine; Humans; S-Adenosylhomocysteine

2010
Impacts of hyper-homocysteinemia and white matter hyper-intensity in Alzheimer's disease patients with normal creatinine: an MRI-based study with longitudinal follow-up.
    Current Alzheimer research, 2010, Volume: 7, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Blood Glucose; Brain; Cholesterol; Cross-Sectional Studies; Fasting; Female; Homocysteine; Humans; Logistic Models; Longitudinal Studies; Magnetic Resonance Imaging; Male; Mental Status Schedule; Nerve Fibers, Myelinated; Neuropsychological Tests

2010
S-adenosylmethionine is decreased in the cerebrospinal fluid of patients with Alzheimer's disease.
    Neuro-degenerative diseases, 2010, Volume: 7, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Apolipoprotein E4; Chi-Square Distribution; Cross-Sectional Studies; Fasting; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Mental Status Schedule; Middle Aged; S-Adenosylmethionine; White People

2010
Aging and antioxidants modulate rat brain levels of homocysteine and dehydroepiandrosterone sulphate (DHEA-S): implications in the pathogenesis of Alzheimer's disease.
    Neuroscience letters, 2010, Oct-11, Volume: 483, Issue:2

    Topics: Aging; Alzheimer Disease; Animals; Antioxidants; Brain; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Homocysteine; Rats; Rats, Wistar

2010
Plasma homocysteine levels and major depressive disorders in Alzheimer disease.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010, Volume: 18, Issue:11

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Depressive Disorder, Major; Female; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Severity of Illness Index

2010
The relationship of cardiovascular risk factors to Alzheimer disease in Choctaw Indians.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2011, Volume: 19, Issue:5

    Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Cardiovascular Diseases; Case-Control Studies; Diabetes Mellitus; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hypertension; Indians, North American; Male; Middle Aged; Oklahoma; Risk Factors; Statistics, Nonparametric; White People

2011
Hyperhomocysteinemia in Alzheimer dementia patients and cognitive decline after 6 months follow-up period.
    Acta neurologica Taiwanica, 2010, Volume: 19, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cognition Disorders; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Retrospective Studies

2010
Depression, Parkinson disease, Alzheimer disease. The homocysteine hypothesis.
    Neurosciences (Riyadh, Saudi Arabia), 2010, Volume: 15, Issue:3

    Topics: Alzheimer Disease; Depression; Homocysteine; Humans; Parkinson Disease

2010
Homocysteine, another risk factor for Alzheimer disease, impairs apolipoprotein E3 function.
    The Journal of biological chemistry, 2010, Dec-03, Volume: 285, Issue:49

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apolipoprotein E3; Apolipoprotein E4; Brain; Disulfides; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Mice; Mice, Knockout; Protein Multimerization; Risk Factors

2010
Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal study.
    Neurology, 2010, Oct-19, Volume: 75, Issue:16

    Topics: Aged; Aging; Alzheimer Disease; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Dementia; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Mental Status Schedule; Odds Ratio; Risk Factors; Transcobalamins

2010
Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation.
    Clinical laboratory, 2010, Volume: 56, Issue:9-10

    Topics: Aged; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neopterin; Oxidative Stress; Protein Carbonylation; Reference Values; Tryptophan; Vitamin B 12

2010
Modulatory effects of vitamin E, acetyl-L-carnitine and α-lipoic acid on new potential biomarkers for Alzheimer's disease in rat model.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:6

    Topics: Alzheimer Disease; Animals; Antioxidants; Biomarkers; Brain; Carnitine; Cholinesterase Inhibitors; Dietary Supplements; Disease Models, Animal; Donepezil; Enzyme-Linked Immunosorbent Assay; Homocysteine; Indans; Insulin-Like Growth Factor I; Interleukin-1beta; Male; Piperidines; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tumor Necrosis Factor-alpha; Vitamin E

2012
Alzheimer disease: homocysteine and alzheimer disease: an intervention study.
    Nature reviews. Neurology, 2011, Volume: 7, Issue:1

    Topics: Alzheimer Disease; Homocysteine; Humans; Randomized Controlled Trials as Topic; Vitamin B Complex

2011
Folate and homocysteine in the cerebrospinal fluid of patients with Alzheimer's disease or dementia: a case control study.
    European neurology, 2011, Volume: 65, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Dementia; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Retrospective Studies; Statistics, Nonparametric; Tunisia

2011
Homocysteine effects on brain volumes mapped in 732 elderly individuals.
    Neuroreport, 2011, Jun-11, Volume: 22, Issue:8

    Topics: Aged; Alzheimer Disease; Brain; Brain Mapping; Cognition Disorders; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male

2011
Biomarkers for cognitive decline: opportunities and challenges.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2011, Volume: 19, Issue:7

    Topics: Aged; Alzheimer Disease; Biomarkers; Dementia; Homocysteine; Humans

2011
Homocysteine in Alzheimer's disease: role of dietary folate, vitamin B6 and B12.
    International journal of geriatric psychiatry, 2011, Volume: 26, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Diet; Diet Records; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6

2011
Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study.
    Journal of Alzheimer's disease : JAD, 2011, Volume: 27, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; Australia; Brain; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Vitamin B 12

2011
Acetyl-L-carnitine attenuates homocysteine-induced Alzheimer-like histopathological and behavioral abnormalities.
    Rejuvenation research, 2011, Volume: 14, Issue:6

    Topics: Acetylcarnitine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Brain; Disease Models, Animal; Hippocampus; Homocysteine; Male; Maze Learning; Phosphorylation; Rats; Rats, Sprague-Dawley; Silver Staining; tau Proteins

2011
Folate, homocysteine, vitamin B12, and polymorphisms of genes participating in one-carbon metabolism in late-onset Alzheimer's disease patients and healthy controls.
    Antioxidants & redox signaling, 2012, Jul-15, Volume: 17, Issue:2

    Topics: Age of Onset; Aged; Alleles; Alzheimer Disease; Biomarkers; Case-Control Studies; Female; Folic Acid; Genotype; Health; Homocysteine; Humans; Male; Polymorphism, Genetic; Vitamin B 12

2012
Plasma homocysteine level and apathy in Alzheimer's disease.
    Journal of the American Geriatrics Society, 2011, Volume: 59, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apathy; Female; Homocysteine; Humans; Male; Sex Factors

2011
Cognitive reserve, homocysteine, and cognition in the Bavarian School Sisters Study.
    Journal of the American Geriatrics Society, 2011, Volume: 59, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Educational Status; Female; Homocysteine; Humans

2011
Effect of N-homocysteinylation on physicochemical and cytotoxic properties of amyloid β-peptide.
    FEBS letters, 2012, Jan-20, Volume: 586, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Chemical Phenomena; Cytotoxins; Homocysteine; Humans; Hyperhomocysteinemia; PC12 Cells; Protein Multimerization; Protein Processing, Post-Translational; Rats; Structure-Activity Relationship

2012
Metabolism and neurotoxicity of homocysteine thiolactone in mice: evidence for a protective role of paraoxonase 1.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 30, Issue:2

    Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Brain; Epilepsy; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kidney; Liver; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Degeneration; Spleen

2012
Predicting missing biomarker data in a longitudinal study of Alzheimer disease.
    Neurology, 2012, May-01, Volume: 78, Issue:18

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognitive Dysfunction; Cohort Studies; Dementia, Vascular; Fluorodeoxyglucose F18; Homocysteine; Humans; Logistic Models; Longitudinal Studies; Magnetic Resonance Imaging; Neuropsychological Tests; Patient Dropouts; Peptide Fragments; Positron-Emission Tomography; Research Design; Risk Factors; tau Proteins

2012
Urinary homocysteic acid levels correlate with mini-mental state examination scores in Alzheimer's disease patients.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 31, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Electrochemistry; Female; Homocysteine; Humans; Male; Mental Status Schedule; Middle Aged; Smoking; Statistics as Topic

2012
Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Biomarkers; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylmethionine; Young Adult

2012
Elevated plasma homocysteine level is not primarily related to Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2012, Volume: 34, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency

2012
Relationship of cognitive function with B vitamin status, homocysteine, and tissue factor pathway inhibitor in cognitively impaired elderly: a cross-sectional survey.
    Journal of Alzheimer's disease : JAD, 2013, Volume: 33, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Mental Status Schedule; Neuropsychological Tests; Vitamin B 12; Vitamin B 12 Deficiency

2013
Altered levels of homocysteine and serum natural antioxidants links oxidative damage to Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2013, Volume: 33, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Neuropsychological Tests; Oxidative Stress

2013
Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.
    Journal of neurochemistry, 2013, Volume: 124, Issue:3

    Topics: Alzheimer Disease; Animals; Betaine; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Male; Memory Disorders; Rats; Rats, Sprague-Dawley

2013
Association between plasma biomarkers, CDK5 polymorphism and the risk of Alzheimer's disease.
    Acta neurobiologiae experimentalis, 2012, Volume: 72, Issue:4

    Topics: Alzheimer Disease; Apolipoproteins E; Cyclin-Dependent Kinase 5; Female; Folic Acid; Genetic Association Studies; Genotype; Homocysteine; Humans; Lipids; Male; Meta-Analysis as Topic; Middle Aged; Polymorphism, Genetic; Riboflavin

2012
Optimal use of markers for cobalamin and folate status in a psychogeriatric population.
    International journal of geriatric psychiatry, 2002, Volume: 17, Issue:10

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12

2002
Homocysteine, stroke, and dementia.
    Stroke, 2002, Volume: 33, Issue:10

    Topics: Aging; Alzheimer Disease; Causality; Comorbidity; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Vitamin B Complex

2002
Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland.
    Stroke, 2002, Volume: 33, Issue:10

    Topics: Aged; Alleles; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Comorbidity; Dementia, Vascular; Female; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Northern Ireland; Nutritional Status; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Risk Assessment; Risk Factors; Statistical Distributions; Stroke

2002
Homocysteine, vitamin B6, and vascular disease in patients with AD.
    Neurology, 2002, Nov-12, Volume: 59, Issue:9

    Topics: Aged; Alzheimer Disease; Female; Homocysteine; Humans; Male; Vascular Diseases; Vitamin B 6

2002
Differential relations between cognition and 15N isotopic content of hair in elderly people with dementia and controls.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2002, Volume: 57, Issue:12

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Animals; Case-Control Studies; Chi-Square Distribution; Diet; Diet Records; Diet, Vegetarian; Female; Fishes; Hair; Homocysteine; Humans; Male; Middle Aged; Nitrogen Isotopes; Regression Analysis

2002
Homocysteine and brain atrophy on MRI of non-demented elderly.
    Brain : a journal of neurology, 2003, Volume: 126, Issue:Pt 1

    Topics: Aged; Alzheimer Disease; Amygdala; Analysis of Variance; Biomarkers; Brain; Cross-Sectional Studies; Female; Hippocampus; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged

2003
Folate delivers head-to-toe health advantages. The B vitamin that benefits unborn babies may also protect the hearts and minds (and colons) of adults.
    Health news (Waltham, Mass.), 2002, Volume: 8, Issue:12

    Topics: Alzheimer Disease; Anencephaly; Colonic Neoplasms; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Male; Pregnancy; Spinal Dysraphism; Stroke

2002
Feeding the aging brain.
    Newsweek, 2003, Jan-20, Volume: 141, Issue:3

    Topics: Aging; Alzheimer Disease; Antioxidants; Brain; Cholesterol; Diet; Dietary Fats; Exercise; Fish Oils; Homocysteine; Humans; Hypertension; United States

2003
Alzheimer's disease and total plasma aminothiols.
    Biological psychiatry, 2003, Feb-01, Volume: 53, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Cysteine; Folic Acid; Glutathione; Homocysteine; Humans; Mental Status Schedule; Neuropsychological Tests; Prognosis; Reference Values; Vitamin B 12

2003
Will caloric restriction and folate protect against AD and PD?
    Neurology, 2003, Feb-25, Volume: 60, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Animals; Brain; Brain-Derived Neurotrophic Factor; Caloric Restriction; Disease Models, Animal; Energy Intake; Folic Acid; Homocysteine; Humans; Middle Aged; Neurons; Oxidative Stress; Parkinson Disease; Rats; Risk Factors

2003
Diet and Alzheimer's disease.
    The Harvard mental health letter, 2003, Volume: 19, Issue:8

    Topics: Alzheimer Disease; Anticholesteremic Agents; Antioxidants; Brain; Cholesterol, HDL; Cholesterol, LDL; Fatty Acids, Omega-3; Homocysteine; Humans; Hypercholesterolemia

2003
[Serum markers in relation to cognitive functioning in an aging population: results of the Maastricht Aging Study (MAAS)].
    Tijdschrift voor gerontologie en geriatrie, 2003, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Biomarkers; C-Reactive Protein; Cholesterol; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Haptoglobins; Homocysteine; Humans; Lanosterol; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Psychomotor Performance

2003
Homocysteine and folate deficiency sensitize oligodendrocytes to the cell death-promoting effects of a presenilin-1 mutation and amyloid beta-peptide.
    Neuromolecular medicine, 2003, Volume: 3, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cell Death; Cells, Cultured; Disease Models, Animal; DNA Damage; Enzyme Inhibitors; Folic Acid Deficiency; Homocysteine; Membrane Proteins; Mice; Mice, Mutant Strains; Mutation; Nerve Fibers, Myelinated; Oligodendroglia; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Presenilin-1; Tumor Suppressor Protein p53; Up-Regulation

2003
Plasma total homocysteine levels, dietary vitamin B6 and folate intake in AD and healthy aging.
    The journal of nutrition, health & aging, 2003, Volume: 7, Issue:3

    Topics: Adult; Aging; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Cholesterol; Educational Status; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Serum Albumin; Smoking; Triglycerides; Vitamin B 6

2003
Homocysteine, apolipoproteine E and methylenetetrahydrofolate reductase in Alzheimer's disease and mild cognitive impairment.
    Dementia and geriatric cognitive disorders, 2003, Volume: 16, Issue:2

    Topics: Aged; Alzheimer Disease; Apolipoproteins E; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12

2003
Homocysteine and the brain: vascular risk factor or neurotoxin?
    The Lancet. Neurology, 2003, Volume: 2, Issue:1

    Topics: Aged; Alzheimer Disease; Brain; Case-Control Studies; Clinical Trials as Topic; Dementia, Vascular; Homocysteine; Humans; Neurotoxins; Risk Factors; Vascular Diseases

2003
Memantine in moderate-to-severe Alzheimer's disease.
    The New England journal of medicine, 2003, Aug-07, Volume: 349, Issue:6

    Topics: Alzheimer Disease; Excitatory Amino Acid Antagonists; Homocysteine; Humans; Hyperhomocysteinemia; Memantine; N-Methylaspartate

2003
Homocysteine and methylenetetrahydrofolate reductase polymorphism in Alzheimer's disease.
    Neuroreport, 2004, Apr-09, Volume: 15, Issue:5

    Topics: Age Factors; Aged; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Case-Control Studies; Confidence Intervals; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Polymorphism, Genetic; Pteroylpolyglutamic Acids; Regression Analysis; Statistics, Nonparametric; Transcobalamins; Vitamin B 12

2004
CT brain findings in clinical dementia investigation--underestimation of mixed dementia.
    Dementia and geriatric cognitive disorders, 2004, Volume: 18, Issue:1

    Topics: Aged; Alzheimer Disease; Atrophy; Basal Ganglia; Cerebral Infarction; Dementia; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Male; Temporal Lobe; Tomography, X-Ray Computed

2004
A haplotype of the methylenetetrahydrofolate reductase gene is protective against late-onset Alzheimer's disease.
    Neurobiology of aging, 2004, Volume: 25, Issue:3

    Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Brain; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Haplotypes; Homocysteine; Humans; Immunity, Innate; Japan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic

2004
Homocysteine and Alzheimer's disease: a modifiable risk?
    Free radical biology & medicine, 2004, Jun-01, Volume: 36, Issue:11

    Topics: Alzheimer Disease; Brain; Cystathionine beta-Synthase; Homocysteine; Humans; Risk Factors

2004
Cerebrospinal fluid tau protein and periventricular white matter lesions in patients with mild cognitive impairment: implications for 2 major pathways.
    Archives of neurology, 2004, Volume: 61, Issue:5

    Topics: Aged; Alzheimer Disease; Apolipoproteins E; Biomarkers; Brain; Cognition Disorders; Dementia; Disease Progression; Female; Follow-Up Studies; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Prospective Studies; Radiography; Risk Factors; tau Proteins

2004
Low thyroid-stimulating hormone as an independent risk factor for Alzheimer disease.
    Neurology, 2004, Jun-08, Volume: 62, Issue:11

    Topics: Aged; Aged, 80 and over; Alcohol Drinking; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Comorbidity; Creatinine; Diabetes Mellitus; England; Female; Follow-Up Studies; Homocysteine; Humans; Hypertension; Male; Odds Ratio; Reference Values; Risk Factors; Serum Albumin; Smoking; Thyrotropin; Thyroxine

2004
Plasma homocysteine levels and risk of Alzheimer disease.
    Neurology, 2004, Jun-08, Volume: 62, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Comorbidity; Confounding Factors, Epidemiologic; Cross-Sectional Studies; Cysteine; Dementia; Diabetes Mellitus; Ethnicity; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Neuropsychological Tests; New York City; Prevalence; Risk Factors; Sampling Studies; Stroke; Vitamin B 12; Vitamin B 6

2004
Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons.
    Journal of neuroscience research, 2004, Jul-01, Volume: 77, Issue:1

    Topics: Alzheimer Disease; Amidohydrolases; Animals; Antioxidants; Arginine; Brain; Cells, Cultured; Cognition Disorders; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Feedback, Physiological; Homocysteine; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Proline; Rats; Thiocarbamates; Up-Regulation

2004
Association of IL-1 RN*2 allele and methionine synthase 2756 AA genotype with dementia severity of sporadic Alzheimer's disease.
    Journal of neurology, neurosurgery, and psychiatry, 2004, Volume: 75, Issue:7

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alleles; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Female; Genotype; Homocysteine; Humans; Interleukin-1; Italy; Male; Middle Aged; Polymorphism, Genetic; Severity of Illness Index

2004
Homocysteine, Alzheimer genes and proteins, and measures of cognition and depression in older men.
    Journal of Alzheimer's disease : JAD, 2004, Volume: 6, Issue:3

    Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Depression; Gene Expression; Homocysteine; Humans; Male; Neuropsychological Tests; Point Mutation; Polymerase Chain Reaction; Severity of Illness Index; Surveys and Questionnaires; Tetrahydrofolates

2004
Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia.
    Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:5

    Topics: 17-alpha-Hydroxypregnenolone; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dementia, Vascular; Dipeptides; Female; Glutathione; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Predictive Value of Tests; Pregnenolone; Radioimmunoassay; Sensitivity and Specificity; Sex Factors; Statistics, Nonparametric; Sulfhydryl Compounds

2004
Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cognition Disorders; Cross-Sectional Studies; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Risk Factors; Switzerland; Vitamin B 12

2004
Plasma homocysteine concentration relates to the severity but not to the duration of Alzheimer's disease.
    International journal of geriatric psychiatry, 2004, Volume: 19, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Disease Progression; Female; Homocysteine; Humans; Male; Regression Analysis; Statistics, Nonparametric; Time Factors

2004
Increased homocysteine and decreased adenosine formation in Alzheimer's disease.
    Neurological research, 2004, Volume: 26, Issue:5

    Topics: Adenosine; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cerebrovascular Disorders; Down-Regulation; Female; Homocysteine; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Neuroprotective Agents; Predictive Value of Tests; S-Adenosylhomocysteine; Up-Regulation

2004
Lack of genetic dispositions to hyperhomocysteinemia in Alzheimer disease.
    American journal of medical genetics. Part A, 2004, Nov-15, Volume: 131, Issue:1

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Age Factors; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Chi-Square Distribution; Cystathionine beta-Synthase; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Genetic; Sex Factors; Survival Analysis

2004
Homocysteine, vitamin B12 and folate in vascular dementia and in Alzheimer disease.
    Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Case-Control Studies; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neurons; Nutritional Status; Oxidative Stress; Vitamin B 12; Vitamin B 12 Deficiency

2004
Studies on homocysteine and dehydroepiandrosterone sulphate plasma levels in Alzheimer's disease patients and in Parkinson's disease patients.
    Neurotoxicity research, 2004, Volume: 6, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dehydroepiandrosterone Sulfate; Female; Homocysteine; Humans; Male; Middle Aged; Parkinson Disease

2004
Plasma homocysteine, vitamin B12 and folate in Alzheimer's patients and healthy Arabs in Israel.
    Journal of the neurological sciences, 2004, Dec-15, Volume: 227, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arabs; Case-Control Studies; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Israel; Male; Odds Ratio; Vitamin B 12

2004
Studies on homocysteine plasma levels in Alzheimer's patients. Relevance for neurodegeneration.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Female; Homocysteine; Humans; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2005
S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production.
    Molecular and cellular neurosciences, 2005, Volume: 28, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Brain; Cell Line, Tumor; Culture Media, Serum-Free; DNA Methylation; Endopeptidases; Folic Acid Deficiency; Gene Expression; Homocysteine; Humans; Membrane Proteins; Presenilin-1; Promoter Regions, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency

2005
Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke.
    Neurology, 2004, Dec-28, Volume: 63, Issue:12

    Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Cholesterol; Dementia, Vascular; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germany; Glutathione Transferase; Homocysteine; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Point Mutation; Polymorphism, Genetic; Stroke

2004
Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
    The American journal of medicine, 2005, Volume: 118, Issue:2

    Topics: Aged; Aging; Alzheimer Disease; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Longitudinal Studies; Male; Risk Factors; Vitamin B 12; Vitamin B 6

2005
Plasma homocysteine concentration and its relation to symptoms of vascular disease in psychogeriatric patients.
    Dementia and geriatric cognitive disorders, 2005, Volume: 20, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Protein S; Vascular Diseases; Vitamin B 12

2005
Homocysteine and related genetic polymorphisms in Down's syndrome IQ.
    Journal of neurology, neurosurgery, and psychiatry, 2005, Volume: 76, Issue:5

    Topics: Alleles; Alzheimer Disease; Apolipoproteins E; Diagnostic and Statistical Manual of Mental Disorders; Down Syndrome; Folic Acid; Homocysteine; Humans; Intelligence; Karyotyping; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Transcobalamins; Vitamin B 12

2005
Homocysteic acid induces intraneuronal accumulation of neurotoxic Abeta42: implications for the pathogenesis of Alzheimer's disease.
    Journal of neuroscience research, 2005, Jun-15, Volume: 80, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; CHO Cells; Cricetinae; Cricetulus; Endopeptidases; Enzyme Inhibitors; Homocysteine; Humans; Inclusion Bodies; Neurons; Peptide Fragments; Rats; Rats, Sprague-Dawley; Rats, Wistar

2005
Homocysteine, vitamin B 12 and folate in Alzheimer's and vascular dementias: the paradoxical effect of the superimposed type II diabetes mellitus condition.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 359, Issue:1-2

    Topics: Aged; Alzheimer Disease; Analysis of Variance; Dementia, Vascular; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12

2005
Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease.
    Life sciences, 2005, Aug-26, Volume: 77, Issue:15

    Topics: Aged; Alzheimer Disease; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Male; Middle Aged; Parkinson Disease

2005
Homocysteine and cognitive function in institutionalised elderly A cross-sectional analysis.
    European journal of nutrition, 2006, Volume: 45, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition; Cross-Sectional Studies; Female; Geriatric Assessment; Homes for the Aged; Homocysteine; Humans; Linear Models; Male; Psychiatric Status Rating Scales

2006
Subjective memory complaints with and without objective memory impairment: relationship with risk factors for dementia.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Anxiety; Apolipoprotein E4; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Risk Factors; Self-Assessment; Sick Role; Western Australia

2005
The relation between homocysteine levels and development of Alzheimer's disease in mild cognitive impairment patients.
    Dementia and geriatric cognitive disorders, 2005, Volume: 20, Issue:4

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Creatinine; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Sex Characteristics; Thyrotropin; Vitamin B 12; Vitamins

2005
Homocysteine and folate as risk factors for dementia and Alzheimer disease.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:3

    Topics: Aged; Aging; Alzheimer Disease; Cognition; Cohort Studies; Cross-Sectional Studies; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Italy; Male; Prospective Studies; Risk Factors; Seroepidemiologic Studies

2005
Cell cycle-related protein expression in Alzheimer's disease and vascular disease.
    International psychogeriatrics, 2003, Volume: 15 Suppl 1

    Topics: Aged; Alzheimer Disease; Apolipoproteins E; Apoptosis; Cerebrovascular Disorders; Homocysteine; Humans

2003
Plasma homocysteine levels are not increased in murine models of Alzheimer's disease.
    Neuroscience research, 2005, Volume: 53, Issue:4

    Topics: Alzheimer Disease; Animals; Biomarkers; Disease Models, Animal; Homocysteine; Humans; Mice; Mice, Transgenic; Risk Factors

2005
Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimer's disease.
    Journal of neurology, neurosurgery, and psychiatry, 2005, Volume: 76, Issue:11

    Topics: Adult; Aged; Alzheimer Disease; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged

2005
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.
    Neurology, 2005, Nov-08, Volume: 65, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12

2005
Homocysteine and cognition--no longer a hypothesis?
    Medical hypotheses, 2006, Volume: 66, Issue:3

    Topics: Aged; Alzheimer Disease; Cognition; Cognition Disorders; Homocysteine; Humans; Methionine; Models, Biological; Models, Theoretical; Neurodegenerative Diseases; Vitamin B 12; Vitamins

2006
A cross-sectional study of homocysteine-, NO-levels, and CT-findings in Alzheimer dementia, vascular dementia and controls.
    Biogerontology, 2005, Volume: 6, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Cross-Sectional Studies; Dementia, Vascular; Homocysteine; Humans; Nitric Oxide; Tomography, X-Ray Computed

2005
Plasma homocysteine and vascular disease in psychogeriatric patients.
    Dementia and geriatric cognitive disorders, 2006, Volume: 21, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Confusion; Dementia; Dementia, Vascular; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Middle Aged; Natriuretic Peptide, Brain; Neuropsychological Tests; Peptide Fragments; Reference Values; Risk Factors; Vitamin B 12

2006
Relationship of homocysteine and gene polymorphisms of its related metabolic enzymes with Alzheimer's disease.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2005, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cystathionine beta-Synthase; Female; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length

2005
Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta peptide levels.
    Neurobiology of disease, 2006, Volume: 22, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Animals; Blotting, Western; Brain; Brain Chemistry; Cell Count; Cystathionine beta-Synthase; Disease Models, Animal; Female; Homocysteine; Immunohistochemistry; Male; Mice; Mice, Transgenic; Mutation; Neurons; Polymerase Chain Reaction; Sex Factors

2006
Relation between vascular risk factors and cognition at age 75.
    Acta neurologica Scandinavica, 2006, Volume: 114, Issue:2

    Topics: Aged; Aging; Alzheimer Disease; Austria; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Cognition Disorders; Cohort Studies; Comorbidity; Cross-Sectional Studies; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperlipidemias; Hypertension; Lipoproteins; Male; Neuropsychological Tests; Risk Factors; Smoking; Statistics as Topic; Triglycerides

2006
Plasma homocysteine and risk of coexisting silent brain infarction in Alzheimer's disease.
    Neuro-degenerative diseases, 2005, Volume: 2, Issue:6

    Topics: Aged; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Cell Death; Cerebral Infarction; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Genotype; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neurons; Peptide Fragments; Risk Factors; tau Proteins; Vitamin B 12

2005
Folate, the methionine cycle, and Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2006, Volume: 9, Issue:4

    Topics: Alzheimer Disease; Brain; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Reactive Oxygen Species; S-Adenosylmethionine

2006
Plasma homocysteine, cobalamin/folate status, and vascular disease in a large population of psychogeriatric patients.
    Dementia and geriatric cognitive disorders, 2006, Volume: 22, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Depressive Disorder; Female; Folic Acid; Hematocrit; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Nutritional Status; Population; Sweden; Vascular Diseases; Vitamin B 12

2006
Abeta peptides as one of the crucial volume transmission signals in the trophic units and their interactions with homocysteine. Physiological implications and relevance for Alzheimer's disease.
    Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cell Communication; Corpus Striatum; Extracellular Space; Glial Fibrillary Acidic Protein; Homocysteine; Male; Nerve Net; Neuroglia; Neurons; Pain Threshold; Peptide Fragments; Plaque, Amyloid; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase

2007
Behavioural and psychological symptoms of Alzheimer type dementia are not correlated with plasma homocysteine concentration.
    Dementia and geriatric cognitive disorders, 2006, Volume: 22, Issue:5-6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Neuropsychological Tests; Psychological Tests; Severity of Illness Index; Vitamin B 12

2006
Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms.
    Arquivos de neuro-psiquiatria, 2006, Volume: 64, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Female; Genetic Markers; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic

2006
Homocysteine and electroencephalographic rhythms in Alzheimer disease: a multicentric study.
    Neuroscience, 2007, Mar-30, Volume: 145, Issue:3

    Topics: Aged; Alzheimer Disease; Biomarkers; Brain; Cognition Disorders; Electroencephalography; Female; Homocysteine; Humans; Male

2007
Relationship of vascular risk to the progression of Alzheimer disease.
    Neurology, 2007, Mar-27, Volume: 68, Issue:13

    Topics: Alzheimer Disease; Apolipoproteins E; Cerebral Arteries; Cerebrovascular Disorders; Cholesterol; Disease Progression; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperlipidemias; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors

2007
Prolonged stress will induce Alzheimer's disease in elderly people by increased release of homocysteic acid.
    Medical hypotheses, 2007, Volume: 69, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Homocysteine; Humans; Mice; Models, Neurological; Rats; Stress, Psychological

2007
Relations between homocysteine, folate and vitamin B12 in vascular dementia and in Alzheimer disease.
    Clinical biochemistry, 2007, Volume: 40, Issue:12

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Risk Factors; Vitamin B 12

2007
Association between vitamin B6 and white matter hyperintensities in patients with Alzheimer's disease not mediated by homocysteine metabolism.
    Journal of the American Geriatrics Society, 2007, Volume: 55, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Homocysteine; Humans; Magnetic Resonance Imaging; Middle Aged; Vitamin B 6

2007
Folate deficiency and plasma homocysteine during increased oxidative stress.
    The New England journal of medicine, 2007, Jul-26, Volume: 357, Issue:4

    Topics: Alzheimer Disease; Animals; Apolipoproteins E; Cardiovascular Diseases; Disease Models, Animal; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Transgenic; Oxidative Stress; Risk Factors

2007
Potential biomarkers for dementia in Trinidad and Tobago.
    Neuroscience letters, 2007, Aug-31, Volume: 424, Issue:1

    Topics: Aged; Alzheimer Disease; Animals; Antibodies; Biomarkers; Blood Chemical Analysis; C-Reactive Protein; Dementia, Vascular; Diagnosis, Differential; Female; Homocysteine; Humans; Male; Microglia; Middle Aged; Neuropsychological Tests; Predictive Value of Tests; Rats; Trinidad and Tobago

2007
gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells.
    Journal of Alzheimer's disease : JAD, 2007, Volume: 11, Issue:3

    Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Antioxidants; Aspartic Acid Endopeptidases; Blotting, Western; Cell Line, Tumor; DNA Methylation; DNA Primers; Folic Acid; Glioblastoma; Homocysteine; Humans; Neuroblastoma; Oxidative Stress; Polymerase Chain Reaction; Presenilin-1; S-Adenosylmethionine; Up-Regulation; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency

2007
Methylenetetrahydrofolate reductase gene and risk of Alzheimer's disease in Koreans.
    International journal of geriatric psychiatry, 2008, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Asian People; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors; Vitamin B 12

2008
Elevated serum homocysteine levels in male patients with PTSD.
    Depression and anxiety, 2008, Volume: 25, Issue:11

    Topics: Adult; Alzheimer Disease; Chronic Disease; Depression; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Schizophrenia; Stress Disorders, Post-Traumatic; Young Adult

2008
Homocysteine induces tau hyperphosphorylation in rats.
    Neuroreport, 2007, Dec-03, Volume: 18, Issue:18

    Topics: Alzheimer Disease; Animals; Binding Sites; Brain; Brain Chemistry; Homocysteine; Hyperhomocysteinemia; Injections, Intraventricular; Male; Neurofibrillary Tangles; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; Serine; tau Proteins; Time Factors

2007
Mercaptopropionaldehyde from homocysteine: implications for Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2007, Volume: 12, Issue:3

    Topics: 3-Mercaptopropionic Acid; Aldehydes; Alzheimer Disease; Amyloid beta-Protein Precursor; Chemical Precipitation; Homocysteine; Humans; Neurofibrillary Tangles; Plaque, Amyloid

2007
Plasma aminothiol compounds, but not serum tumor necrosis factor receptor II and soluble receptor for advanced glycation end products, are related to the cognitive impairment in Alzheimer's disease and mild cognitive impairment patients.
    Neuroimmunomodulation, 2007, Volume: 14, Issue:3-4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Cysteine; Down-Regulation; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Tumor Necrosis Factor, Type II; Sulfhydryl Compounds; Up-Regulation

2007
Changes in folate, vitamin B12 and homocysteine associated with incident dementia.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:8

    Topics: Activities of Daily Living; Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Mental Status Schedule; Neuropsychological Tests; Predictive Value of Tests; Prospective Studies; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency

2008
Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease.
    Neurobiology of aging, 2009, Volume: 30, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Apolipoprotein E4; China; Female; Folic Acid; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk Factors; Sex Factors

2009
Synergistic induction of ER stress by homocysteine and beta-amyloid in SH-SY5Y cells.
    The Journal of nutritional biochemistry, 2008, Volume: 19, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum; Folic Acid; Homocysteine; Humans; Models, Biological; Protein Binding; Reactive Oxygen Species; Ultraviolet Rays

2008
Post-methionine load test: A more sensitive tool to reveal hyperhomocysteinemia in Alzheimer patients?
    Clinical biochemistry, 2008, Volume: 41, Issue:10-11

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Sensitivity and Specificity

2008
CSF/serum folate gradient: physiology and determinants with special reference to dementia.
    Dementia and geriatric cognitive disorders, 2008, Volume: 25, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood-Brain Barrier; Case-Control Studies; Choroid Plexus; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Risk Factors; Serum Albumin; Vitamin B 12

2008
Is metabolic evidence for vitamin B-12 and folate deficiency more frequent in elderly patients with Alzheimer's disease?
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1997, Volume: 52, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Female; Folic Acid Deficiency; Homocysteine; Hospitalization; Humans; Male; Methylmalonic Acid; Reference Values; Vitamin B 12 Deficiency

1997
Total serum homocysteine in senile dementia of Alzheimer type.
    International journal of geriatric psychiatry, 1998, Volume: 13, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biological Transport, Active; Case-Control Studies; Cognition; Creatinine; Diet; Female; Folic Acid; Homocysteine; Humans; Learning; Male; Memory; Prospective Studies; Psychiatric Status Rating Scales; Reference Values; Regression Analysis; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency

1998
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.
    Archives of neurology, 1998, Volume: 55, Issue:11

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Memory Disorders; Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Risk Factors; Vascular Diseases; Vitamin B 12

1998
Vascular involvement in cognitive decline and dementia. Epidemiologic evidence from the Rotterdam Study and the Rotterdam Scan Study.
    Annals of the New York Academy of Sciences, 2000, Volume: 903

    Topics: Aged; Alzheimer Disease; Arteriosclerosis; Atrial Fibrillation; Brain; Cerebrovascular Circulation; Cognition Disorders; Cross-Sectional Studies; Dementia; Diabetes Mellitus; Female; Homocysteine; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Netherlands; Prospective Studies; Risk Factors; Smoking

2000
Leukoaraiosis at presentation and disease progression during follow-up in histologically confirmed cases of dementia.
    Annals of the New York Academy of Sciences, 2000, Volume: 903

    Topics: Aged; Alzheimer Disease; Blood Pressure; Brain; Dementia, Vascular; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Mental Status Schedule; Retrospective Studies; Tomography, X-Ray Computed

2000
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene and vascular dementia.
    Journal of the American Geriatrics Society, 2000, Volume: 48, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Case-Control Studies; Dementia, Vascular; Female; Gene Frequency; Homocysteine; Humans; Israel; Jews; Male; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Polymorphism, Genetic; Tomography, X-Ray Computed

2000
[Alzheimer's disease: from pathology to preventive methods?].
    La Revue de medecine interne, 2000, Volume: 21, Issue:6

    Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins E; Chromosomes, Human, Pair 19; Homocysteine; Humans; Nutritional Status

2000
Treatment of cobalamin deficiency in dementia, evaluated clinically and with cerebral blood flow measurements.
    Aging (Milan, Italy), 2000, Volume: 12, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Circulation; Dementia, Vascular; Female; Homocysteine; Humans; Hydroxocobalamin; Injections, Intramuscular; Male; Methylmalonic Acid; Regional Blood Flow; Vitamin B 12 Deficiency

2000
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment.
    Mechanisms of ageing and development, 2000, Dec-20, Volume: 121, Issue:1-3

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Dementia; Dementia, Vascular; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Male; Pyridoxine; Reference Values; Vitamin B 12

2000
Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways.
    Journal of neurochemistry, 2001, Volume: 76, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Copper; Dose-Response Relationship, Drug; Drug Synergism; Homocysteine; Humans; Kinetics; Mice; Mice, Inbred Strains; Neurons; Neurotoxins; Risk Factors

2001
Hyperhomocysteinemia in dementia.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:12

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Pilot Projects; Reference Values; Regression Analysis; Risk Factors; Vitamin B 12

2000
One-carbon metabolism and other biochemical correlates of cognitive impairment as visualized by principal component analysis.
    Journal of geriatric psychiatry and neurology, 2001,Fall, Volume: 14, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Atrophy; Brain; Cognition Disorders; Dementia, Vascular; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Reference Values; Severity of Illness Index; tau Proteins; Vitamin B 12

2001
Nutrition. B vitamins.
    Harvard health letter, 2001, Volume: 27, Issue:2

    Topics: Age Factors; Alzheimer Disease; Diet; Homocysteine; Humans; Myocardial Infarction; Vitamin B 12; Vitamin B 6

2001
Homocysteine and dementias.
    The New England journal of medicine, 2002, Feb-14, Volume: 346, Issue:7

    Topics: Alzheimer Disease; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex

2002
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.
    The New England journal of medicine, 2002, Feb-14, Volume: 346, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Confounding Factors, Epidemiologic; Dementia; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Multivariate Analysis; Proportional Hazards Models; Risk Factors

2002
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Mar-01, Volume: 22, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Cells, Cultured; Diet; Disease Models, Animal; DNA Damage; DNA Repair; Folic Acid Deficiency; Hippocampus; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Transgenic; Neurons; Rats; Uracil

2002
In praise of folic acid.
    Time, 2002, Feb-25, Volume: 159, Issue:8

    Topics: Alzheimer Disease; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Spinal Dysraphism; United States

2002
Homocysteine may raise Alzheimer's risk. Keep homocysteine levels in check by getting enough folic acid in your diet.
    Health news (Waltham, Mass.), 2002, Volume: 8, Issue:4

    Topics: Aged; Alzheimer Disease; Biomarkers; Folic Acid; Homocysteine; Humans

2002
Protein phosphatase 2A methylation: a link between elevated plasma homocysteine and Alzheimer's Disease.
    FEBS letters, 2002, May-08, Volume: 518, Issue:1-3

    Topics: Alzheimer Disease; Homocysteine; Humans; Methylation; Models, Biological; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Risk Factors; tau Proteins

2002
Functional vitamin B(12) deficiency and Alzheimer disease.
    Neurology, 2002, May-14, Volume: 58, Issue:9

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alzheimer Disease; Brain; Homocysteine; Humans; Hyperhomocysteinemia; Oxidation-Reduction; Oxidative Stress; Vitamin B 12; Vitamin B 12 Deficiency

2002
Plasma homocysteine levels, cerebrovascular risk factors, and cerebral white matter changes (leukoaraiosis) in patients with Alzheimer disease.
    Archives of neurology, 2002, Volume: 59, Issue:5

    Topics: Aged; Alzheimer Disease; Brain; Brain Diseases; Case-Control Studies; Cerebrovascular Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Nerve Fibers; Risk Factors; Tomography, X-Ray Computed

2002
Homocysteine, vitamin B6, and vascular disease in AD patients.
    Neurology, 2002, May-28, Volume: 58, Issue:10

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Angina Pectoris; Brain Infarction; Coronary Disease; Female; Heart Failure; Homocysteine; Humans; Ischemic Attack, Transient; Male; Myocardial Infarction; Odds Ratio; Pyridoxal Phosphate; Stroke; Vascular Diseases; Vitamin B 6

2002
Relation between plasma homocysteine and Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2002, Volume: 14, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Homocysteine; Humans; Male; Matched-Pair Analysis; Vascular Diseases

2002
Brain hydrogen sulfide is severely decreased in Alzheimer's disease.
    Biochemical and biophysical research communications, 2002, May-24, Volume: 293, Issue:5

    Topics: Alzheimer Disease; Amino Acids; Blotting, Western; Brain; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Humans; Hydrogen Sulfide; S-Adenosylmethionine

2002
Homocysteine and dementia.
    The New England journal of medicine, 2002, Jun-20, Volume: 346, Issue:25

    Topics: Alzheimer Disease; Brain; Homocysteine; Humans

2002
Homocysteine and dementia.
    The New England journal of medicine, 2002, Jun-20, Volume: 346, Issue:25

    Topics: Alzheimer Disease; Blood Chemical Analysis; Fasting; Homocysteine; Humans

2002