homocysteine and Aging

homocysteine has been researched along with Aging in 346 studies

Research

Studies (346)

TimeframeStudies, this research(%)All Research%
pre-19907 (2.02)18.7374
1990's37 (10.69)18.2507
2000's193 (55.78)29.6817
2010's93 (26.88)24.3611
2020's16 (4.62)2.80

Authors

AuthorsStudies
Chen, LK; Lee, WJ; Loh, CH; Peng, LN1
Chen, ZK; Jiang, XY; Ma, T; Sun, XH; Wang, XF; Xu, WD; Yao, S; Zhang, JF1
Cao, Y; Chai, J; Dai, H; Ji, D; Luo, C; Wang, W; Xue, K; Yan, W; Zhang, S; Zhang, X; Zhang, Y1
Atienza, M; Cantero, JL; Palomar-Bonet, M1
Azzini, E; Polito, A; Ruggeri, S1
Bross, P; Carlsen, J; Dipace, G; Gregersen, N; Mosegaard, S; Olsen, RKJ1
McCully, KS5
Jungert, A; Neuhäuser-Berthold, M; Zenke-Philippi, C1
Al-Shabrawey, M; Elsherbiny, NM; Samra, YA; Tawfik, A1
Baccarelli, AA; Boyer, EW; Colicino, E; Gao, X; Nwanaji-Enwerem, JC; Schwartz, J; Vokonas, P; Wang, C1
Bakker, SJL; Berendsen, AAM; Bialecka-Debek, A; de Groot, LCPGM; Deen, CPJ; Fairweather-Tait, S; Feskens, EJM; Franceschi, C; Grootswagers, P; Jennings, A; Kema, IP; Malpuech-Brugère, C; Mensink, M; Meunier, N; Rolf, K; Santoro, A1
Castro, F; Chavez, CA; de Erausquin, GA; Lee, JH; Maestre, GE; Melgarejo, J; Terwilliger, JD1
Gong, W; Jiang, X; Jin, L; Luo, D; Shen, H; Sun, X; Wang, J; Wang, X; Xu, X; Zhang, H1
Dai, C; Fei, Y; Li, J; Shi, Y; Yang, X1
Cameron-Smith, D; Franzke, B; Gillies, NA; Hofmann, M; Milan, AM; Oesen, S; Roy, NC; Schober-Halper, B; Strasser, EM; Tosevska, A; Wagner, KH; Wessner, B1
Arutjunyan, AV; Milyutina, YP; Pustygina, AV; Zaloznyaya, IV1
Cynober, L; Deutz, NE; Engelen, MP; Ligthart-Melis, GC; Simbo, SY; Smriga, M1
Antikainen, H; Dobrowolski, R; Khayati, K1
Day, RS; Luo, ST; Pettee Gabriel, K; Simonsick, EM; Vidoni, ML1
Bodis, M; Geisel, J; Graeber, S; Hübner, U; Obeid, R1
Bosi, C; Brombo, G; Cervellati, C; Morieri, ML; Passaro, A; Trentini, A; Valacchi, G; Zuliani, G; Zurlo, A1
Borowczyk, K; Jakubowski, H; Suliburska, J1
Granic, A; Hill, TR; Jagger, C; Martin-Ruiz, C; Mathers, JC; Mendonça, N; Seal, CJ1
Arning, E; Bottiglieri, T; Hoffman, A; Qian, H; Sontag, E; Sontag, JM; Taleski, G; Wasek, B1
Brodmann, M; Gary, T; Hackl, G; Hafner, F; Jud, P; Meinitzer, A; Seinost, G; Verheyen, N1
Ostrakhovitch, EA; Tabibzadeh, S1
Chrysohoou, C; Critselis, E; Drosatos, A; Foscolou, A; Katsimardos, A; Panagiotakos, DB; Pitsavos, C; Rallidis, LS; Tousoulis, D; Tsirebolos, G1
Casey, MC; Cunningham, C; Hoey, L; Hughes, CF; Laird, E; McCarroll, K; McNulty, H; Molloy, AM; Moore, K; O'Kane, M; Strain, JJ; Tracey, F; Ward, M1
Fu, S; Luan, F; Lv, F; Yao, Y; Zhang, F; Zhao, Y1
Cheng, DM; Huang, CY; Jiang, YG; Kong, HY; Liu, J; Pang, W; Sun, SD1
den Heijer, M; Heymans, MW; Lips, P; Schaap, LA; Swart, KM; van Schoor, NM1
Abo-Krysha, N; Allam, M; Amer, H; El-Sawy, E; Elatti, SA; Fahmy, E1
Brasili, E; Capuani, G; Finamore, A; Marini, F; Mengheri, E; Miccheli, A; Roselli, M; Sciubba, F; Tomassini, A1
Choi, JS; Choi, SW; Jeong, SK; Kim, BH; Kim, HN; Kweon, SS; Lee, YH; Nam, HS; Park, KS; Shin, MH1
Cheng, D; Huang, C; Jiang, Y; Kong, H; Lu, H; Pang, W; Yang, H1
Armitage, J; Bennett, D; Clarke, R; Collins, R; Dangour, AD; de Groot, LC; Eussen, SJ; Galan, P; Grodstein, F; Halsey, J; Hankey, GJ; Lewerin, C; Lewington, S; Lonn, E; Parish, S; Skeaff, M; Spence, JD; Stott, DJ1
Audureau, E; Dicko, M; Giraudier, S; Krypciak, S; Mézière, A; Monié, M; Vairelles, S1
Naziroğlu, M; Övey, İS1
Solomon, LR1
Agrawal, A; Dubey, GP; Ilango, K; Karmakar, D; Kumari, R; Singh, GP; Singh, PK1
Garrard, P; Jacoby, R1
de Jager, CA; Refsum, H; Rosenberg, IH; Smith, AD1
Bennett, D; Clarke, R; Parish, S1
Hopp, FA; Miller, JR; Prkic, I; Stucke, AG; Stuth, EA; Zuperku, EJ1
Harris, E; Macpherson, H; Pipingas, A1
Medina Escobar, P; Meier, DW; Nydegger, U; Risch, C; Risch, L; Risch, M; Sakem, B1
Han, XH; Jia, YG; Liu, YX; Pan, JD; Qu, BG; Su, JL; Wang, H; Wang, YF; Wang, ZD1
Atienza, M; Cantero, JL; Llado-Saz, S1
Chen, Y; Hu, Y; Li, J; Li, T; Mo, Z; Qin, X; Yang, X; Zhang, H1
Brouwer-Brolsma, EM; Brug, J; de Groot, LC; Dhonukshe-Rutten, RA; Enneman, AW; Ham, AC; Lips, P; Sohl, E; Swart, KM; Uitterlinden, AG; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Schoor, NM; van Wijngaarden, JP; Zillikens, MC1
Cui, NH; Han, YD; Huang, ZL; Li, ZH; Qiao, C; Wang, XB; Wei, L; Yan, M; Zheng, F1
Abbondanza, S; Davin, A; Guaita, A; Mangieri, M; Polito, L; Poloni, TE; Vaccaro, R; Villani, S1
Min, JY; Min, KB1
Biolo, G; di Prampero, PE; Gabrijelčič Blenkuš, M; Gasparini, M; Grassi, B; Lazzer, S; Marusic, U; Mazzucco, S; Mohammed, S; Narici, M; Passaro, A; Pišot, R; Reggiani, C; Rittweger, J; Šimunič, B; Toniolo, L1
Refsum, H; Smith, AD1
Andel, R; Gažová, I; Hort, J; Laczó, J; Lerch, O; Marková, H; Pařízková, M; Vyhnálek, M1
Hedman, ÅK; Ingelsson, E; Lind, L; Sundström, J; Zilmer, M1
Spence, JD1
Adachi, T; Kobayashi, Y; Ochi, A1
Brouwer, IA; Elstgeest, LE; Penninx, BW; van Schoor, NM; Visser, M1
Aoki, Y; Era, S; Hasegawa, H; Hashimoto, T; Matsuyama, Y; Shinohara, Y; Soejima, A; Suzuki, Y1
Brahmachari, V; Garg, G; Karthikeyan, G; Kumar, A; Kumar, J; Patowary, A; Ramakrishnan, L; Sengupta, S; Sharma, P1
Dalle-Donne, I; Giustarini, D; Milzani, A; Rossi, R1
Bruce, I; Chin, AV; Coakley, D; Coen, R; Cunningham, CJ; Hamilton, F; Lawlor, BA; Molloy, A; O'Connell, H; Robinson, DJ; Scott, J; Walsh, B1
Brouwer, IA; Clarke, R; Katan, MB; Verhoef, P; Winkels, RM1
Allen, CL; Bayraktutan, U1
Smith, AD2
Cascalheira, JF; Domingues, FC; Faria, MC; Parreira, MC; Viegas, AN1
Gustafson, L; Hultberg, B; Nilsson, K5
Green, R; Luchsinger, JA; Mayeux, R; Miller, J; Tang, MX1
Comijs, HC; Deeg, DJ; Dik, MG; Jonker, C; van den Kommer, TN1
Breteler, MM; de Lau, LM; Johnston, C; Refsum, H; Smith, AD; Uitterlinden, AG; van Meurs, JB1
Badiou, S; Cristol, JP; Dupuy, AM; Durant, R; Jaussent, A; Jeandel, C; Morena, M; Picot, MC; Ventura, E1
de Groot, LC; Knoops, KT; Kromhout, D; Spiro, A; Tucker, KL; van Staveren, WA1
Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J4
Alp, HH; Ates, O; Azizi, S; Baykal, O; Beydemir, S; Cinici, E; Kiziltunc, A; Kocer, I1
Berstad, P; Drevon, CA; Nurk, E; Refsum, H; Smith, AD; Tell, GS; Ueland, PM; Vogiatzoglou, A; Vollset, SE1
Ochudło, S; Opala, G; Siuda, J; Targosz-Gajniak, M1
Druga, R; Folbergrová, J; Haugvicová, R; Otáhal, J; Tsenov, G1
Björkelund, C; Guo, X; Gustafson, D; Lissner, L; Mehlig, K; Ostling, S; Skoog, I; Thelle, DS; Waern, M; Zylberstein, DE1
Colla, M; Endres, M; Kronenberg, G1
Bindels, JG; Blauw, YH; de Groot, CP; Dhonukshe-Rutten, RA; Manders, M; Siebelink, E; van Hoeckel-Prüst, L; van Staveren, WA1
Cagnacci, A; Cannoletta, M; Volpe, A1
Burrin, D; Castillo, L; Chacko, S; Gordon, WE; Hsu, J; Sy, J; Verbruggen, S; Wu, M; Zurakowski, D1
Kuriyama, N; Mitani, S; Mizuno, T; Ozaki, E; Ozasa, K; Shigeta, M; Watanabe, Y; Yokota, S1
Bull, CF; Fenech, MF; Mayrhofer, G; O'Callaghan, NJ1
Burlutsky, G; Flood, VM; Gopinath, B; Mitchell, P; Wang, JJ; Wong, TY1
Calevo, MG; Cotellessa, M; d'Annunzio, G; Giannattasio, A; Gianotti, D; Lorini, R; Minniti, G; Napoli, F1
Butterfield, DA; Calabrese, V; Cornelius, C; Lentile, R; Mancuso, C; Stella, AM1
Li, Y; Liu, Y; Richardson, B; Strickland, FM1
Alpert, DR; Cooke, JP; Crow, MK; Devereux, RB; Lockshin, MD; Perna, M; Roman, MJ; Salmon, JE; Sammaritano, L1
Allen, LH; Garrod, MG; Green, R; Haan, MN; Miller, JW1
Hu, CP; Li, YJ; Tan, GS; Wang, CJ; Xu, KP1
Allen, RH; Davey, A; Hausman, DB; Johnson, MA; Poon, LW; Stabler, SP1
Besanger, A; Biffi, A; Butler, C; Chang, Y; Cloonan, L; Delgado, P; Furie, KL; Gilson, A; Jimenez-Conde, J; Kanakis, A; Massasa, E; Rahman, R; Rosand, J; Rost, NS; Silva, G; Smith, EE; Sonni, S1
Flood, VM; Gopinath, B; McMahon, CM; Mitchell, P; Rochtchina, E1
Barbagallo, M; Belvedere, M; Ciaccio, M; Costanza, G; Dominguez, LJ; Ferlisi, A; Galioto, A; Pineo, A; Putignano, E1
Cheng, DM; Huang, CY; Jiang, YG; Kong, HY; Pang, W; Yang, HP1
Basu, S; Chakrabarti, S; Pal, K; Saha, A; Sinha, M1
Eckert, R; Herrmann, W; Kasoha, M; Kirsch, SH; Obeid, R1
Chen, S; Chen, X; Chen, Y; Chu, W; Ho, CL; Hu, X; Leung, EY; Mok, V; Schmidt, R; Tang, WK; Wong, A; Wong, KK; Wong, KS; Wong, ST; Xiong, Y1
Ahtiluoto, S; Hooshmand, B; Kåreholt, I; Kivipelto, M; Laatikainen, T; Leiviskä, J; Rusanen, M; Soininen, H; Solomon, A; Winblad, B1
Breilmann, J; Brunner, C; Neuhäuser-Berthold, M; Pons-Kühnemann, J; Richter, M1
Rosenberg, IH; Selhub, J; Troen, A1
Beran-Praher, M; Fuchs, D; Haller, H; Leblhuber, F; Schroecksnadel, K; Steiner, K1
Almeida, OP; Flicker, L; Ford, AH; Hankey, GJ; Norman, P; van Bockxmeer, FM1
Brown, B; Huang, MH; Kado, D; Karlamangla, A; Seeman, T1
Chatthanawaree, W1
Apeland, T; Bates, CJ; Drabløs, PA; Hervig, T; Mansoor, MA; Stakkestad, JA; Wentzel-Larsen, T1
Firbank, MJ; Ford, GA; Hansrani, M; Harrington, F; McKeith, IG; Narayan, SK; O'Brien, JT; Saxby, BK; Stansby, G1
Alevizaki, M; Mantzou, A; Mara, C; Panoutsopoulos, A; Papageorgiou, G; Saltiki, K; Terzidis, K; Tourli, P; Tsagalis, G1
de Groot, RH; Durga, J; Jolles, J; Kok, FJ; Schiepers, OJ; van Boxtel, MP; Verhoef, P1
Ames, D; Bush, AI; Ellis, KA; Faux, NG; Fowler, CJ; Laws, SM; Martins, RN; Masters, CL; Pertile, KK; Porter, L; Rembach, A; Rowe, CC; Rumble, RL; Szoeke, C; Taddei, K; Taddei, T; Trounson, BO; Villemagne, VL; Ward, V1
Chen, MF; Jeng, JS; Liau, CS; Su, TC; Torng, PL1
Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M1
Ganapathy, P; Peachey, NS; Smith, SB; Sturgill-Short, G; Tawfik, A; Yu, M1
Goto, M; Iwaki-Egawa, S; Watanabe, Y1
Casson, RI; Dodds, L; Ho, V; King, WD; Massey, TE; Perkins, SL1
Kim, JH; Lee, DC1
Alverson, PB; Ayling, JE; Bailey, SW; Boilson, A; Daly, L; Kelleher, CC; MacCooey, A; McDermott, AP; Scott, JM; Shirley, I; Shrivastava, A; Staines, A; Sweeney, MR1
de Groot, LC; Geerlings, MI; Jochemsen, HM; Kampman, E; Kloppenborg, RP; Mali, WP; van der Graaf, Y1
Blom, HJ; Farkas, M; Jessen, F; Linnebank, M; Popp, J; Semmler, A; Smith, DE; Smulders, YM1
Elanchezhian, R; Lynch, DW; Madson, CJ; Palsamy, P; Shinohara, T1
Aung, KC; Feng, L; Ng, TP; Scherer, SC; Yap, KB1
Ehlert, U; Kuebler, U; La Marca, R; Linnebank, M; Semmler, A; Stoffel-Wagner, B; Wirtz, PH1
Attia, JR; Carru, C; Mangoni, AA; McEvoy, M; Zinellu, A1
Forman, DE1
Haugvicová, R; Kubová, H; Mares, P1
Dong, C; Goldschmidt-Clermont, PJ; Yoon, W1
Coccheri, S; Cosmi, B; Grossi, G; Legnani, C; Musolesi, S; Palareti, G; Sassi, S1
Baydas, G; Canatan, H; Canpolat, S; Cikim, G; Gursu, MF; Kelestimur, H; Yasar, A1
Korczyn, AD1
Lain, KY; Lykins, DL; Majors, AK; Powers, RW; Roberts, JM; Sims, CJ1
Breteler, MM; Clarke, R; Den Heijer, T; Hofman, A; Jolles, J; Koudstaal, PJ; Prins, ND1
Bradley, KM; Budge, MM; Pereira, EA; Williams, JH1
Bertrais, S; de Courcy, GP; Ducros, V; Favier, A; Franchisseur, C; Galan, P; Guilland, JC; Hercberg, S; Maurel, M; Mennen, LI; Nicolas, JP; Zarebska, M1
Bucur, A; Kado, DM; Rowe, JW; Seeman, T; Selhub, J1
Grodstein, F; Stampfer, MJ1
Mattson, MP; Shea, TB1
Arnone, G; Forti, P; Maioli, F; Mariani, E; Muscari, A; Nativio, V; Ravaglia, G; Sacchetti, L; Talerico, T1
Mattson, MP1
Aleksic, N; Cushman, M; Folsom, AR; Heckbert, SR; Psaty, BM; Rosamond, WD; Tsai, AW; Tsai, MY; Yanez, ND1
Blom, HJ; Bosma, H; Bosmans, E; De Bruijn, C; de Vente, J; Delanghe, J; Jolles, J; Lütjohann, D; Maes, M; Steinbusch, HW; Teunissen, CE; van Boxtel, MP; von Bergmann, K; Wauters, A1
Ganji, V; Kafai, MR3
Bailey, LB; Gregory, JF; Herrlinger-Garcia, K; Kauwell, GP; Theriaque, DW; Wolfe, JM1
Gustafson, L; Hultberg, B; Isaksson, A; Nilsson, K1
Balas, D; Bouzigon, E; Emeriau, JP; Parrot, F; Rainfray, M; Salles-Montaudon, N1
Blom, AH; Bosma, H; de Bruijn, C; de Vente, J; Jolles, J; Steinbusch, HW; Teunissen, CE; Van Boxtel, MP; Wauters, BA1
Debanne, SM; Friedland, RP; Jacobsen, DW; Lerner, AJ; Mizrahi, EH; Petot, GJ; Traore, F1
Crimmins, EM; Hayward, M; Johnston, M; Seeman, T1
Selley, ML1
Chada, L; McGaw, J; Nakano, E; Powers, HJ; Taylor, CJ1
Bodis, M; Geisel, J; Herrmann, W; Hübner, U; Knapp, JP; Obeid, R; Schorr, H1
Geisel, J; Herrmann, W; Obeid, R; Schorr, H1
Ahn, C; Aronow, WS; Storey, SG; Suryadevara, V1
Bernick, C; Carr, JJ; Cushman, M; Hess, DL; Katz, R; Longstreth, WT; Malinow, MR; Olson, J; Schwartz, SM1
Allen, JC; Boyd, LC; Hoffman, M; Sauls, DL1
Collins, G; Dawson, H; Deep-Dixit, V; Pyle, R; Taub, DD1
Bermudez, OI; Gao, X; Tucker, KL1
Bakun, P; Dallal, GE; Olson, B; Rosenberg, IH; Selhub, J; Tucker, KL1
Andersen, ML; Bignotto, M; D'Almeida, V; Martins, PJ; Santos, RF; Tufik, S1
Clarke, S; Vitali, R1
Hartmann, B; Krems, C; Lührmann, PM; Neuhäuser-Berthold, M; Strassburg, A1
Frick, B; Fuchs, D; Leblhuber, F; Neurauter, G; Schroecksnadel, K1
Bursztyn, M1
Arranz-Peña, ML; Luis, DD; Pérez-Castrillón, JL1
Allen, LH; Green, R; Haan, MN; Miller, JW; Ramos, MI1
Bald, E; Chwatko, G; Iciek, M; Lorenc-Koci, E; Włodek, L1
Ferrari, CK1
Almeida, OP; Flicker, L; Lautenschlager, NT; Leedman, P; van Bockxmeer, FM; Vasikaran, S1
Aleman, A; de Haan, EH; Muller, M; van der Schouw, YT1
Huang, MH; Kado, DM; Karlamangla, AS; Rowe, JW; Seeman, TE; Selhub, J; Troen, A1
Chetrit, A; Dankner, R; Lubin, F; Sela, BA1
Andersen, ML; Benedito-Silva, AA; D'Almeida, V; Galdieri, LC; Martins, PJ; Souza, FG; Tufik, S1
Engedal, K; Hestad, K; Kveberg, B1
Ito, T; Sakuta, H; Suzuki, T; Yasuda, H1
Andria, G; Scala, I; Sebastio, G1
Cesari, M; Pessina, AC; Rossi, GP; Sticchi, D1
Afman, L; Blom, HJ; den Heijer, M; Oppenraay-van Emmerzaal, D; Thomas, CM; van Beynum, IM1
Bruschi, F; Crosignani, PG; Daguati, R; Dal Pino, D; Di Pace, R; Fiore, V; Maffioletti, C; Melotti, D; Moroni, S; Parazzini, F; Rossi, M1
Motobayashi, S; Nakamuro, K; Okuno, T; Ueno, H1
Belmaker, RH; Levine, J; Osher, Y; Sela, BA1
Dainty, JR; de Meer, K; Finglas, PM; Jakobs, C; Kok, RM; Smith, DE; Smulders, YM; Stehouwer, CD1
Doherty, GH; Foister, NS; Mackie, JB; Oldreive, CE1
Bottiglieri, T; Diaz-Arrastia, R1
Brunetti, N; Forti, P; Licastro, F; Maioli, F; Martelli, M; Porcellini, E; Ravaglia, G; Servadei, L1
Qiao, N; Rosenberg, I; Scott, T; Spiro, A; Tucker, KL1
Chen, JH; Hashmi, A; Kuo, HK; Lipsitz, LA; Milberg, WP; Sorond, FA1
Chillemi, R; D'Agata, A; Minucci, A; Musumeci, S; Persichilli, S; Simpore, J1
de Craen, AJ; Frölich, M; Gussekloo, J; Jolles, J; Mooijaart, SP; Stott, DJ; Westendorp, RG1
Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M1
Allen, LH; Green, R; Haan, MN; Jagust, WJ; Miller, JW; Mungas, DM; Ramos, MI1
Breuillé, D; Buffière, C; Gimonet, J; Mercier, S; Mirand, PP; Obled, C; Papet, I1
Duranay, M; Parpucu, H; Senes, M; Tekeli, N; Yilmaz, FM; Yilmaz, G; Yücel, D1
Gensler, G; Klein, ML; Milton, RC; Seddon, JM1
Arvanitidou, M; Makedou, A; Mavromichalis, I; Papandreou, D; Rousso, I2
Herrmann, W; Obeid, R1
Ingenbleek, Y1
Bjelland, I; Gjesdal, CG; Nurk, E; Nygård, O; Refsum, H; Smith, AD; Tell, GS; Tverdal, A; Ueland, PM; Vollset, SE1
Bode-Böger, SM; Bukowska, A; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Täger, M1
Abe, Y; Akashi, S; Aoyagi, K; Hara, T; Kusano, Y; Maeda, T; Nakashima, K; Nakazato, M; Takamura, N; Wada, M1
Bauer, K; Fischer, P; Huber, K; Jungwirth, S; Tragl, KH; Zehetmayer, S1
Carlsson, CM1
Caccamo, D; Chirico, C; Condello, S; Ferlazzo, N; Gorgone, G; Ientile, R; Picerno, I; Visalli, G1
Dyer, CB; Goodwin, JS; Kala, G; Kelly, PA; Mathews Oliver, SA; Smith, SM; Zwart, SR1
Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB1
Födinger, M; Hubmann, M; Huemer, M; Krumpholz, R; Simma, B; Ulmer, H; Vonblon, K1
Alaveras, A; Harris, F; Kalofoutis, A; Kalofoutis, C; Phoenix, D; Piperi, C; Singh, J; Zisaki, A1
Bianchin, M; Chiappelli, M; Forti, P; Licastro, F; Maioli, F; Montesi, F; Patterson, C; Ravaglia, G1
Chuah, L; Feng, L; Kua, EH; Ng, TP; Niti, M1
Becker, G; Fassbender, K; Herrmann, W; Kasoha, M; Knapp, JP; Kostopoulos, P; Obeid, R1
Anteunis, LJ; Durga, J; Kok, FJ; Schouten, E; Verhoef, P1
Greenwald, SE1
Feinstein, D; Ilie, JI; Jurivich, DA; Perez, FP; Zhou, X1
Aronow, WS1
Aiello, AE; Allen, LH; Green, R; Haan, MN; Jagust, WJ; Miller, JW; Mungas, DM; Whitmer, RA1
Elia, M; Guéant, JL; Romano, A1
Anello, G; Benamghar, L; Bosco, P; Calabrese, S; Fontaine, T; Guéant, JL; Guéant-Rodriguez, RM; Romano, A; Spada, RS; Stella, G1
Anello, G; Benamghar, L; Bosco, P; Calabrese, S; Castellano, A; Fajardo, A; Guéant, JL; Guéant-Rodriguez, RM; Lipari, L; Proto, C; Romano, A; Sirna, S; Spada, RS; Stella, G1
Lavie, L; Lavie, P1
Fernández, S; González, S; Huerta, JM; Lasheras, C; Patterson, AM1
Doherty, GH1
Cushman, M; Jenny, NS; Katz, R; Psaty, BM; Reiner, AP; Schwartz, SM; Zakai, NA1
Bean, JF; Chen, JH; Kuo, HK; Leveille, SG; Liao, KC; Tai, TY; Yen, CJ; Yu, YH1
Sohal, RS; Toroser, D1
Hasegawa, T1
Albers, U; Alder, M; Barrios, L; Castillo, MJ; Gonzalez-Gross, M; Pietrzik, K; Sola, R1
Chou, YF; Huang, RF; Yu, CC1
Breteler, MM; de Lau, LM; Johnston, C; Refsum, H; Smith, AD1
Boziki, M; Gavalas, E; Kountouras, J; Zavos, C1
Allen, RH; Barbosa, PR; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Luchessi, AD; Stabler, SP; Trentin, R1
Barschak, AG; Matté, C; Netto, CA; Scherer, EB; Stefanello, FM; Vargas, CR; Wyse, AT1
Fanghänel, J; Gedrange, T; Maile, S; Proff, P; Weingärtner, J1
Allen, RH; De Chicchis, AR; Johnson, MA; Park, S; Shea-Miller, K; Stabler, SP1
Abe, Y; Aoyagi, K; Kusano, Y; Maeda, T; Nakashima, K; Nakazato, M; Takamura, N; Wada, M1
Barraud, H; Bronowicki, JP; Guéant, JL; Lalonde, R; Ravey, J; Strazielle, C1
Schulz, RJ1
Blom, H; den Heijer, M; Hogeveen, M; Kluijtmans, L; van Beynum, I; van Rooij, A1
Brachet, P; Cardinault, N; Chanson, A; D'Incan, M; Martin, JF; Rock, E; Souteyrand, P1
Bi, XH; Zhang, JW; Zhang, ZX; Zhao, HL1
Chabannes, B; Cronenberger, L; Gharib, A; Pacheco, H; Sarda, N1
Adão, M; Azinheira, J; Bordalo e Sá, AL; Ferreira, NC; Luís, AS; Pina, JE; Reis, HP; Reis, RP; Santos, L; Vilaverde, MM1
García-Cuevas, M; Pérez-Olleros, L; Ruiz-Roso, B; Varela-Moreiras, G1
Allen, RH; Lindenbaum, J; Rosenberg, IH; Stabler, SP; Wilson, PW1
Jacques, PF; Rosenberg, IH; Rush, D; Selhub, J; Wilson, PW1
McCully, KS; Olszewski, AJ1
Riggs, KM; Rush, D; Spiro, A; Tucker, K1
Dybkjaer, L; Lyngbak, M; Møller, J; Pedersen, AM; Rasmussen, K1
Joosten, E; Lesaffre, E; Riezler, R1
Arheart, K; Chaudhary, D; Dennis, V; Green, R; Gupta, A; Jacobsen, DW; Kutner, M; Mayer, EL; Robinson, K; Selhub, J; Vigo, P1
Azen, C; Carmel, R; Green, R; Howard, JM; Jacobsen, DW1
Folbergrová, J1
Eckfeldt, JH; Folsom, AR; Garg, UC; McGovern, P; Moyer, YS; Tsai, MY; Zheng, ZJ1
Baumgartner, RN; Garry, PJ; Koehler, KM; Pareo-Tubbeh, SL; Romero, LJ1
Dejaeger, E; Dereymaeker, L; Ghekiere, V; Joosten, E; Lesaffre, E; Pelemans, W; Riezler, R1
Folbergrová, J; Haugvicová, R; Lisý, V; Stastný, F1
Rosenberg, IH2
Grobbee, DE; Kok, FJ; Kruyssen, DA; Refsum, H; Schouten, EG; Ueland, PM; Verhoef, P; Witteman, JC1
Bostom, A; Selhub, J; Sutton-Tyrrell, K; Zeigler-Johnson, C1
Bottiglieri, T; Lowenthal, D; Parnetti, L1
Nygård, O; Refsum, H; Ueland, PM; Vollset, SE2
Chook, P; Sanderson, JE; Woo, KS; Young, RP1
Artuch, R; Lambruschini, N; Moyano, D; Valls, C; Vilaseca, MA1
Clarke, R; Frost, C; Khaw, KT; Refsum, H; Sherliker, P; Ueland, PM; Ulvik, A; Woodhouse, P1
Fex, G; Grubb, A; Hultberg, B; Leksell, H; Nilsson, JE; Norlund, L; Schenck, H1
Clarke, R; Jobst, KA; Refsum, H; Smith, AD; Sutton, L; Ueland, PM1
Ubbink, JB1
Wilcken, B; Wilcken, DE1
Berglund, L; Berne, C; Brattström, L; Refsum, H; Ueland, PM; Wollesen, F1
Appel, LJ; Maguire, MG; Miller, ER; Selhub, J; Stolzenberg-Solomon, RZ1
Moustapha, A; Robinson, K1
Bodis, M; Geisel, J; Herrmann, W; Quast, S; Schultze, H; Ullrich, M1
Aranda, JV; Bardin, CL; Hoffer, LJ; Hongsprabhas, P; Kovacs, LB; Papageorgiou, AN; Saboohi, F1
Bächli, E; Fehr, J1
Baggott, JE1
Angst, C; Fowler, B; Haefeli, WE; Litynski, P; Loehrer, F; Todesco, L1
Chao, CL; Kuo, TL; Lee, YT1
Hackam, DG; Peterson, JC; Spence, JD1
Bagley, LC; Miller, J; Rosenberg, IH; Selhub, J1
Archbold, GP; Harmon, DL; Lennox, S; Linton, T; McMaster, D; McNulty, H; Rea, IM; Whitehead, AS; Woodside, JV; Young, IS1
Arnalich, F; Fernández-Vivancos, E; Hernanz, A; Salazar, RM1
Stabler, SP1
Krumdieck, CL; Prince, CW1
Barnetson, L; Budge, M; de Jager, C; Hogervorst, E; Iversen, SD; Johnston, C; King, E; Milwain, E; Smith, AD1
Arnalich, F; Fernández-Vivancos, E; Hernanz, A; Montiel, C; Vazquez, JJ1
McCarty, MF1
Refsum, H; Schneede, J; Ueland, PM1
Berner, B; Odum, L; Parving, A1
Dodson, PM; Jones, AF; Marr, JE; Martin, N; Martin, SC; Rauz, S1
Bülow, I; Knudsen, N; Laurberg, P; Ovesen, L; Perrild, H; Rasmussen, LB1
Delvin, EE; Genest, J; Lambert, M; Merouani, A; Rozen, R1
Blumberg, JB; Dallal, G; McKay, DL; Perrone, G; Rasmussen, H1
Delport, R1
Caldarera, M; Cucinotta, D; Dalmonte, E; Forti, P; Grossi, G; Macini, P; Maioli, F; Ravaglia, G; Zanardi, V1
Arakawa, K; Coetzee, GA; Lee, HP; Ong, CN; Saw, SM; Yu, MC; Yuan, JM1
Bargossi, AM; Caldarera, M; Cavalli, G; Facchini, A; Forti, P; Franceschi, C; Grossi, G; Maioli, F; Mariani, E; Ravaglia, G; Vettori, C1
Braconi, M; Franceschi, C; Mazzanti, L; Mutus, B; Paolisso, G; Rabini, RA; Ragno, E; Rappelli, A; Rizzo, MR1
Halsted, CH1
Allen, RH; Baumgartner, RN; Garry, PJ; Koehler, KM; Rimm, EB; Stabler, SP1
Dekou, V; Ebrahim, S; Gudnason, V; Humphries, SE; Lennon, L; Papacosta, O; Refsum, H; Ueland, PM; Whincup, P1
Arai, Y; Ebihara, Y; Hirose, N; Homma, S; Nakazawa, S; Shimizu, K; Takayama, M; Yamamura, K1
Bousquet, B; Gamra, S; Gourmel, B; Houze, P; Madelaine, I1
Alberti, L; Calzoni, F; Fellin, R; Passaro, A; Solini, A; Vanini, A; Zamboni, PF1
Duell, PB; Kario, K; Kato, H; Matsuo, T; Miyata, T; Sakata, T; Shimada, K1
González-Gross, M; Marcos, A; Pietrzik, K1
Naurath, HJ1
Delvin, EE; Genest, J; Lambert, M; Merouani, A; Robitaille, P; Rozen, R1
Suzuki, M; Wilcox, BJ; Wilcox, CD1
Blennow, K; Hill, D; Hudson, P; McCaddon, A; Regland, B1
Panini, R; Salvioli, G; Scarpetta, G; Ventura, P; Verlato, C1
Andrés, P; Bermejo, LM; Faci, M; Jiménez, A; Lolo, JM; Lopez-Sobaler, AM; Lozano, MC; Ortega, RM; Requejo, AM1
Anderson, PH; Block, PC; Duell, PB; Evans, AA; Graf, EE; Hess, DL; Irvin-Jones, A; Kruger, WD; Malinow, MR; Upson, BM; Wang, L; Williams, MA1
Bissoli, L; Bosello, O; Brocco, G; Di Francesco, V; Faccini, G; Mandragona, R; Mazzali, G; Tosoni, P; Zamboni, M; Zivelonghi, A; Zoico, E1
Buysschaert, M; Dramais, AS; Hermans, MP; Jamart, J; Wallemacq, P1
Bates, CJ; Gregory, J; Mansoor, MA; Pentiev, K; Prentice, A1
Berger, K; Collins, AR; Deary, IJ; Duthie, SJ; Leaper, S; Whalley, LJ1
Brodaty, H; Looi, JC; Sachdev, PS; Valenzuela, M; Wang, XL1
Duan, W; Kruman, II; Mattson, MP1
Bermudez, OI; Kwan, LL; Tucker, KL1
Cornatzer, WE; Duerre, JA; Hoffman, DR1
Kjellström, T; Nordström, M1
Andersson, A; Brattström, L; Hamfelt, A; Hultberg, B; Isaksson, A; Israelsson, B1
Gharib, A; Reynaud, D; Sarda, N1
Brattström, LE; Hardebo, JE; Hultberg, BL1
Carnegie, PR; Jones, GM1
Johnston, GA1
Finkelstein, JD; Harris, BJ; Kyle, W1

Reviews

50 review(s) available for homocysteine and Aging

ArticleYear
Homocysteine: Its Possible Emerging Role in At-Risk Population Groups.
    International journal of molecular sciences, 2020, Feb-20, Volume: 21, Issue:4

    Topics: Aging; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Cardiovascular Diseases; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Neurodegenerative Diseases; Osteoporosis; Pre-Eclampsia; Pregnancy; Risk Factors

2020
Riboflavin Deficiency-Implications for General Human Health and Inborn Errors of Metabolism.
    International journal of molecular sciences, 2020, May-28, Volume: 21, Issue:11

    Topics: Acyl-CoA Dehydrogenases; Aging; Animals; Diet; Electron Transport; Energy Metabolism; Fatty Acids; Female; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Genetic Variation; Homocysteine; Humans; Immune System; Metabolism, Inborn Errors; Mitochondria; Mutation; Phenotype; Pregnancy; Protein Folding; Riboflavin; Riboflavin Deficiency

2020
Environmental Pollution, Oxidative Stress and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis and Aging.
    Annals of clinical and laboratory science, 2020, Volume: 50, Issue:3

    Topics: Aging; Animals; Atherosclerosis; Carcinogenesis; Electromagnetic Fields; Environmental Pollution; Fluorides; Glycine; Glyphosate; Homocysteine; Humans; Hyperhomocysteinemia; Mitochondria; Neoplasms; Oxidative Phosphorylation; Oxidative Stress; Vitamin B 12

2020
Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction.
    Biomolecules, 2020, 07-29, Volume: 10, Issue:8

    Topics: Aging; Alzheimer Disease; Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Endoplasmic Reticulum Stress; Homocysteine; Humans; Hyperhomocysteinemia; Macular Degeneration; Oxidative Stress

2020
Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging.
    Annals of clinical and laboratory science, 2020, Volume: 50, Issue:5

    Topics: Aging; Animals; Arteriosclerosis; Cholesterol; Diterpenes; Homocysteine; Humans; Mitochondria; NAD; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Phosphorylation; Permeability; Squalene; Tocotrienols; Vitamin B 12

2020
A Novel Review of Homocysteine and Pregnancy Complications.
    BioMed research international, 2021, Volume: 2021

    Topics: Abortion, Habitual; Aging; Birth Weight; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency

2021
    Annals of clinical and laboratory science, 2018, Volume: 48, Issue:5

    Topics: Aging; Animals; Atherosclerosis; Calcium; Cellular Senescence; Dementia; Homocysteine; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NAD; Nitric Oxide; Oxidative Phosphorylation; Telomere

2018
Homocysteine Metabolism, Atherosclerosis, and Diseases of Aging.
    Comprehensive Physiology, 2015, Dec-15, Volume: 6, Issue:1

    Topics: Aging; Animals; Atherosclerosis; Homocysteine; Humans

2015
Homocysteine, B Vitamins, and Cognitive Impairment.
    Annual review of nutrition, 2016, 07-17, Volume: 36

    Topics: Aging; Animals; Biomarkers; Cerebrovascular Circulation; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nootropic Agents; Nutritional Status; Practice Guidelines as Topic; Risk Factors; Vitamin B 12; Vitamin B 6

2016
Risk factors for ischaemic stroke.
    International journal of stroke : official journal of the International Stroke Society, 2008, Volume: 3, Issue:2

    Topics: Aging; Atherosclerosis; Atrial Fibrillation; Brain Ischemia; Heart Failure; Homocysteine; Humans; Hypertension; Leukocyte Count; Risk Factors; Stroke; Waist-Hip Ratio

2008
The worldwide challenge of the dementias: a role for B vitamins and homocysteine?
    Food and nutrition bulletin, 2008, Volume: 29, Issue:2 Suppl

    Topics: Aged; Aged, 80 and over; Aging; Dementia; Environment; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B Complex

2008
Folic acid, neurodegenerative and neuropsychiatric disease.
    Current molecular medicine, 2009, Volume: 9, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Brain; Clinical Trials as Topic; Dementia, Vascular; Depression; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Molecular Structure; Neurodegenerative Diseases; Neuronal Plasticity; Stroke; Vitamin B Complex

2009
B vitamins and the aging brain.
    Nutrition reviews, 2010, Volume: 68 Suppl 2

    Topics: Aged; Aging; Brain; Cognition Disorders; Homocysteine; Humans; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex

2010
Biomarkers of cobalamin (vitamin B12) deficiency and its application.
    The journal of nutrition, health & aging, 2011, Volume: 15, Issue:3

    Topics: Aging; Biomarkers; Cognition Disorders; Erythrocyte Indices; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency

2011
DNA methylation and atherosclerosis.
    The Journal of nutrition, 2002, Volume: 132, Issue:8 Suppl

    Topics: Aging; Arteriosclerosis; DNA Methylation; Gene Silencing; Homocysteine; Humans

2002
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
    Trends in neurosciences, 2003, Volume: 26, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke

2003
The role of genetic factors in the development of hyperhomocysteinemia.
    Clinical chemistry and laboratory medicine, 2003, Volume: 41, Issue:11

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Aged, 80 and over; Aging; Catechol O-Methyltransferase; Diet, Vegetarian; Folic Acid Deficiency; Genotype; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Mutation; Thymidylate Synthase; Transcobalamins; Vitamin B 12 Deficiency

2003
The immunoregulatory effects of homocysteine and its intermediates on T-lymphocyte function.
    Mechanisms of ageing and development, 2004, Volume: 125, Issue:2

    Topics: Aged; Aging; Apoptosis; Homocysteine; Humans; T-Lymphocytes

2004
Functional foods, herbs and nutraceuticals: towards biochemical mechanisms of healthy aging.
    Biogerontology, 2004, Volume: 5, Issue:5

    Topics: Aging; Antioxidants; Chelating Agents; Food; Heart Diseases; Herbal Medicine; Homocysteine; Humans; Lipoproteins, LDL; Mitochondrial Diseases; Oxidative Stress

2004
Health implications of homocysteine and folates: possible preventive measures.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2005, Volume: 15, Issue:2

    Topics: Aging; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Preventive Medicine; Risk Factors; Sex Characteristics

2005
Is homocysteine important as risk factor for coronary heart disease?
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2005, Volume: 15, Issue:2

    Topics: Aging; Coronary Disease; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prospective Studies; Risk Factors; Sex Characteristics

2005
High homocysteine serum levels in young male schizophrenia and bipolar patients and in an animal model.
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aging; Animals; Behavior, Animal; Bipolar Disorder; Disease Models, Animal; Homocysteine; Humans; Male; Mice; Middle Aged; Schizophrenia; Sex Factors

2005
The role of homocysteine in multisystem age-related problems: a systematic review.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2005, Volume: 60, Issue:9

    Topics: Aging; Animals; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors

2005
Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia.
    FEBS letters, 2006, May-29, Volume: 580, Issue:13

    Topics: Aging; Animals; Central Nervous System; Dementia; Homocysteine; Humans; Neurodegenerative Diseases; Rats

2006
The nutritional relationship linking sulfur to nitrogen in living organisms.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Aging; Animals; Body Composition; Diet; Homeostasis; Homocysteine; Humans; Methionine; Methylation; Nitrates; Nitrogen; Nutritional Physiological Phenomena; Oxidation-Reduction; Plants, Edible; Prealbumin; Protein Deficiency; Stress, Physiological; Sulfates; Sulfur

2006
The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Adult; Aged; Aging; Bone Density; Cardiovascular Diseases; Cognition Disorders; Depression; Disease; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mortality; Norway; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors

2006
Homocysteine lowering with folic acid and vitamin B supplements: effects on cardiovascular disease in older adults.
    Drugs & aging, 2006, Volume: 23, Issue:6

    Topics: Adult; Aging; Animals; Cardiovascular Diseases; Clinical Trials as Topic; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex; Vitamin B Deficiency

2006
Ageing of the conduit arteries.
    The Journal of pathology, 2007, Volume: 211, Issue:2

    Topics: Aging; Arteries; Blood Pressure; Calcinosis; Elasticity; Elastin; Endothelium, Vascular; Fetal Development; Glycation End Products, Advanced; Homocysteine; Humans; Matrix Metalloproteinases; Stress, Mechanical

2007
Peripheral arterial disease.
    Geriatrics, 2007, Volume: 62, Issue:1

    Topics: Aging; Diabetes Mellitus; Dyslipidemias; Foot; Homocysteine; Humans; Hypertension; Hypothyroidism; Peripheral Vascular Diseases; Pharmaceutical Preparations; Risk Factors; Skin Care; Smoking; Smoking Cessation

2007
Homocysteine: more than just a matter of life and death.
    Experimental neurology, 2007, Volume: 205, Issue:1

    Topics: Aging; Animals; Homocysteine; Humans; Neurodegenerative Diseases; Neurotoxins; Risk Factors

2007
Homocysteine as a biomarker for cognitive dysfunction in the elderly.
    Current opinion in clinical nutrition and metabolic care, 2007, Volume: 10, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Cognition Disorders; Diagnosis, Differential; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Predictive Value of Tests; Vitamin B Complex

2007
Homocysteine metabolism and the oxidative modification of proteins and lipids.
    Free radical biology & medicine, 1993, Volume: 14, Issue:6

    Topics: Aging; Animals; Arteriosclerosis; Free Radicals; Homocysteine; Humans; Lipid Metabolism; Models, Biological; Oxidation-Reduction; Proteins; Sulfhydryl Compounds

1993
Folate nutrition and older adults: challenges and opportunities.
    Journal of the American Dietetic Association, 1997, Volume: 97, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Food, Fortified; Homocysteine; Homocystinuria; Humans; Male; Nutritional Status; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency

1997
Nutrition and senescence.
    Nutrition reviews, 1997, Volume: 55, Issue:1 Pt 2

    Topics: Adipose Tissue; Aging; Homocysteine; Humans; Life Expectancy; Nutritional Physiological Phenomena

1997
Role of homocysteine in age-related vascular and non-vascular diseases.
    Aging (Milan, Italy), 1997, Volume: 9, Issue:4

    Topics: Aged; Aging; Alcoholism; Central Nervous System; Cerebrovascular Disorders; Cognition; Coronary Disease; Depression; Estrogens; Female; Folic Acid Deficiency; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Peripheral Vascular Diseases; Renal Replacement Therapy; Vascular Diseases; Vitamin B 12 Deficiency

1997
New risk factors for coronary heart disease in Asia.
    International journal of cardiology, 1997, Dec-01, Volume: 62 Suppl 1

    Topics: Adult; Aged; Aging; Asia; Child; Cholesterol, HDL; Coronary Disease; Endothelium, Vascular; Homocysteine; Humans; Hyperlipidemias; Insulin Resistance; Middle Aged; Obesity; Risk Factors; Smoking

1997
Should all elderly people receive folate supplements?
    Drugs & aging, 1998, Volume: 13, Issue:6

    Topics: Aged; Aging; Coronary Disease; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Nutritional Requirements; Nutritional Status

1998
B vitamins and homocysteine in cardiovascular disease and aging.
    Annals of the New York Academy of Sciences, 1998, Nov-20, Volume: 854

    Topics: Aging; Cardiovascular Diseases; Diet; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Pyridoxine; Risk Factors; Vitamin B 12; Vitamin B Deficiency

1998
Homocysteine: an emerging age-related cardiovascular risk factor.
    Geriatrics, 1999, Volume: 54, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Menopause; Methionine; Middle Aged; Prevalence; Primary Health Care; Risk Factors

1999
[Diagnosis of vitamin B12 deficiency: only apparently child's play].
    Schweizerische medizinische Wochenschrift, 1999, Jun-12, Volume: 129, Issue:23

    Topics: Aging; Anemia, Pernicious; Blood Cell Count; Diagnosis, Differential; Folic Acid Deficiency; Gastritis, Atrophic; Gastroscopy; Homocysteine; Humans; Methylmalonic Acid; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency

1999
B vitamins, homocysteine, and neurocognitive function in the elderly.
    The American journal of clinical nutrition, 2000, Volume: 71, Issue:2

    Topics: Aging; Animals; Brain; Cognition Disorders; Homocysteine; Humans; Methionine; Tetrahydrofolates; Vitamin B Deficiency

2000
Mechanisms of homocysteine toxicity on connective tissues: implications for the morbidity of aging.
    The Journal of nutrition, 2000, Volume: 130, Issue:2S Suppl

    Topics: Aging; Animals; Chronic Disease; Connective Tissue; Epidermal Growth Factor; Homocysteine; Humans; Hyperhomocysteinemia

2000
Biological and environmental determinants of plasma homocysteine.
    Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:3

    Topics: Adult; Aged; Aging; Alcohol Drinking; Child; Cystathionine beta-Synthase; Diagnosis-Related Groups; Dietary Proteins; Endocrine System Diseases; Female; Folic Acid Antagonists; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Inflammation; Intestinal Diseases; Life Style; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Niacin; Nitrous Oxide; Norway; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Renal Insufficiency; Smoking; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency

2000
Hyperhomocyst(e)inemia, related vitamins and dementias.
    The journal of nutrition, health & aging, 2000, Volume: 4, Issue:4

    Topics: Aged; Aging; Dementia; Dietary Supplements; Folic Acid Deficiency; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B 12 Deficiency

2000
[Suggestions from a centenarian study--aging and inflammation].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001, Volume: 38, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Homocysteine; Humans; Inflammation; Nutritional Status; Quality of Life; von Willebrand Factor

2001
B vitamins, homocysteine, and neurocognitive function.
    Nutrition reviews, 2001, Volume: 59, Issue:8 Pt 2

    Topics: Aging; Alzheimer Disease; Cognition Disorders; Gastritis, Atrophic; Homocysteine; Humans; Nutritional Status; Vitamin B Deficiency

2001
Nutrition and cognitive impairment in the elderly.
    The British journal of nutrition, 2001, Volume: 86, Issue:3

    Topics: Aged; Aging; Alzheimer Disease; Antioxidants; Avitaminosis; Dementia; Dementia, Vascular; Dietary Supplements; Educational Status; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hypertension; Life Style; Nutritional Physiological Phenomena; Nutritional Status; Risk Factors; Stroke; Vitamin B 12 Deficiency

2001
Implications from and for food cultures for cardiovascular disease: longevity.
    Asia Pacific journal of clinical nutrition, 2001, Volume: 10, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Antioxidants; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Diet; Female; Gonadal Steroid Hormones; Homocysteine; Humans; Japan; Life Style; Longevity; Male; Neoplasms, Hormone-Dependent; Risk Factors

2001
Homocysteine, B vitamins, and cognitive deficit in the elderly.
    The American journal of clinical nutrition, 2002, Volume: 75, Issue:5

    Topics: Aging; Cognition Disorders; Folic Acid; Homocysteine; Humans; Vitamin B 12

2002
Folic acid and homocysteine in age-related disease.
    Ageing research reviews, 2002, Volume: 1, Issue:1

    Topics: Aged; Aging; Cardiovascular Diseases; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Mental Disorders; Neoplasms; Neurodegenerative Diseases; Stroke

2002

Trials

28 trial(s) available for homocysteine and Aging

ArticleYear
Nutritional supplementation alters associations between one-carbon metabolites and cardiometabolic risk profiles in older adults: a secondary analysis of the Vienna Active Ageing Study.
    European journal of nutrition, 2022, Volume: 61, Issue:1

    Topics: Aged; Aging; Betaine; Carbon; Cardiovascular Diseases; Choline; Dietary Supplements; Female; Homocysteine; Humans; Male

2022
Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2018, Volume: 28, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Calcium Carbonate; Cholecalciferol; CpG Islands; Dietary Supplements; DNA Methylation; Double-Blind Method; Epigenesis, Genetic; Female; Folic Acid; Germany; Homocysteine; Humans; Male; Middle Aged; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2018
Homocysteine, Thioretinaco Ozonide, and Oxidative Phosphorylation in Cancer and Aging: A Proposed Clinical Trial Protocol.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1866

    Topics: Adult; Aged; Aging; Drugs, Investigational; Homocysteine; Humans; Licensure; Middle Aged; Neoplasms; Oxidative Phosphorylation; Vitamin B 12

2019
B vitamin supplementation improves cognitive function in the middle aged and elderly with hyperhomocysteinemia.
    Nutritional neuroscience, 2016, Volume: 19, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; China; Cognitive Dysfunction; Dietary Supplements; Elder Nutritional Physiological Phenomena; Female; Folic Acid; Follow-Up Studies; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nursing Homes; Prevalence; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12; Vitamin B 6

2016
Improved blood biomarkers but no cognitive effects from 16 weeks of multivitamin supplementation in healthy older adults.
    Nutrients, 2015, May-19, Volume: 7, Issue:5

    Topics: Aged; Aging; Biomarkers; C-Reactive Protein; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Female; Homocysteine; Humans; Lipids; Male; Middle Aged; Oxidative Stress; Reference Values; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamins

2015
Serum Homocysteine Concentration Is Significantly Associated with Inflammatory/Immune Factors.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; C-Reactive Protein; Complement C4; Homocysteine; Humans; Immunoglobulin M; Immunologic Factors; Inflammation Mediators; Male; Middle Aged

2015
A Randomized Controlled Trial to Examine the Effect of 2-Year Vitamin B12 and Folic Acid Supplementation on Physical Performance, Strength, and Falling: Additional Findings from the B-PROOF Study.
    Calcified tissue international, 2016, Volume: 98, Issue:1

    Topics: Accidental Falls; Aged; Aged, 80 and over; Aging; Dietary Supplements; Female; Folic Acid; Hand Strength; Homocysteine; Humans; Male; Motor Activity; Osteoporotic Fractures; Physical Fitness; Vitamin B 12

2016
Bread cofortified with folic acid and vitamin B-12 improves the folate and vitamin B-12 status of healthy older people: a randomized controlled trial.
    The American journal of clinical nutrition, 2008, Volume: 88, Issue:2

    Topics: Aged; Aging; Bread; Double-Blind Method; Erythrocytes; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency

2008
Effect of a nutrient-enriched drink on dietary intake and nutritional status in institutionalised elderly.
    European journal of clinical nutrition, 2009, Volume: 63, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Anthropometry; Double-Blind Method; Energy Intake; Female; Food, Fortified; Health Status; Homes for the Aged; Homocysteine; Humans; Male; Malnutrition; Micronutrients; Minerals; Nursing Homes; Nutritional Requirements; Nutritional Status; Vitamins; Weight Gain

2009
Concentrations of unmetabolized folic acid and primary folate forms in plasma after folic acid treatment in older adults.
    Metabolism: clinical and experimental, 2011, Volume: 60, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex

2011
Cortical and frontal atrophy are associated with cognitive impairment in age-related confluent white-matter lesion.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:1

    Topics: Aged; Aging; Atrophy; Cerebral Amyloid Angiopathy; Cerebral Cortex; Cognition Disorders; Double-Blind Method; Executive Function; Female; Frontal Lobe; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Predictive Value of Tests; Regression Analysis; Stroke

2011
DNA methylation and cognitive functioning in healthy older adults.
    The British journal of nutrition, 2012, Volume: 107, Issue:5

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Aging; Cognitive Dysfunction; Cross-Sectional Studies; Cytosine; DNA Methylation; Double-Blind Method; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Genetic Association Studies; Homocysteine; Humans; Leukocytes; Male; Middle Aged; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales

2012
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
    The British journal of nutrition, 2012, Volume: 108, Issue:7

    Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause

2012
Folate catabolite excretion is responsive to changes in dietary folate intake in elderly women.
    The American journal of clinical nutrition, 2003, Volume: 77, Issue:4

    Topics: 4-Aminobenzoic Acid; Aged; Aged, 80 and over; Aging; Diet; DNA Methylation; Erythrocytes; Female; Folic Acid; Glutamates; Homocysteine; Humans; Kinetics; Middle Aged; Nutritional Status; para-Aminobenzoates

2003
Increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with Alzheimer's disease.
    Neurobiology of aging, 2003, Volume: 24, Issue:7

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Arginine; Enzyme Inhibitors; Female; Homocysteine; Humans; Male; Matched-Pair Analysis; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Reference Values; Statistics as Topic

2003
Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial.
    The American journal of clinical nutrition, 2004, Volume: 79, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Double-Blind Method; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6

2004
[6S]5-methyltetrahydrofolate or folic acid supplementation and absorption and initial elimination of folate in young and middle-aged adults.
    European journal of clinical nutrition, 2005, Volume: 59, Issue:12

    Topics: Adult; Aging; Area Under Curve; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Intestinal Absorption; Male; Middle Aged; Tetrahydrofolates

2005
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
    Poultry science, 2006, Volume: 85, Issue:10

    Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation

2006
Effects of folic acid supplementation on hearing in older adults: a randomized, controlled trial.
    Annals of internal medicine, 2007, Jan-02, Volume: 146, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Auditory Threshold; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Hearing Loss, Sensorineural; Homocysteine; Humans; Male; Middle Aged

2007
Age-related hearing loss, methylmalonic acid, and vitamin B12 status in older adults.
    Journal of nutrition for the elderly, 2006, Volume: 25, Issue:3-4

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cohort Studies; Creatinine; Dietary Supplements; Dose-Response Relationship, Drug; Female; Geriatric Assessment; Hearing Loss; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Socioeconomic Factors; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2006
Decreased plasma folate concentration in young and elderly healthy subjects after a short-term supplementation with isotretinoin.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2008, Volume: 22, Issue:1

    Topics: Acne Vulgaris; Adult; Aged; Aging; Dermatologic Agents; Dietary Supplements; Folic Acid; Homocysteine; Humans; Isotretinoin; Male; Tetrahydrofolates

2008
High homocysteine levels are independently related to isolated systolic hypertension in older adults.
    Circulation, 1997, Sep-16, Volume: 96, Issue:6

    Topics: Aged; Aging; Arteriosclerosis; Case-Control Studies; Elasticity; Female; Homocysteine; Humans; Hypertension; Male; Middle Aged; Prevalence; Risk Factors; Systole

1997
Association of dietary protein intake and coffee consumption with serum homocysteine concentrations in an older population.
    The American journal of clinical nutrition, 1999, Volume: 69, Issue:3

    Topics: Aged; Aging; Antioxidants; Body Mass Index; Coffee; Coronary Artery Disease; Diet Records; Dietary Proteins; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Linear Models; Male; Middle Aged; Vitamins

1999
Hyperhomocysteinemia in high-aged subjects: relation of B-vitamins, folic acid, renal function and the methylenetetrahydrofolate reductase mutation.
    Atherosclerosis, 1999, Volume: 144, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Regression Analysis; Risk Assessment; Risk Factors; Statistics, Nonparametric; Vitamin B 12

1999
What level of plasma homocyst(e)ine should be treated? Effects of vitamin therapy on progression of carotid atherosclerosis in patients with homocyst(e)ine levels above and below 14 micromol/L.
    American journal of hypertension, 2000, Volume: 13, Issue:1 Pt 1

    Topics: Aging; Arteriosclerosis; Carotid Artery Diseases; Disease Progression; Female; Homocysteine; Humans; Hypolipidemic Agents; Lipids; Male; Middle Aged; Risk Factors; Sex Characteristics; Vitamins

2000
Influence of methylenetetrahydrofolate reductase genotype, age, vitamin B-12, and folate status on plasma homocysteine in children.
    The American journal of clinical nutrition, 2000, Volume: 72, Issue:6

    Topics: Adolescent; Aging; Chi-Square Distribution; Child; Child, Preschool; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Radioimmunoassay; Vitamin B 12

2000
Multivitamin/mineral supplementation improves plasma B-vitamin status and homocysteine concentration in healthy older adults consuming a folate-fortified diet.
    The Journal of nutrition, 2000, Volume: 130, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cerebrovascular Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Minerals; Nutritional Status; Pyridoxal Phosphate; Risk Factors; Vitamin B 12; Vitamin B Complex; Vitamins

2000
Plasma homocysteine concentration in children with chronic renal failure.
    Pediatric nephrology (Berlin, Germany), 2001, Volume: 16, Issue:10

    Topics: Adolescent; Aging; Child; Child, Preschool; Diet; Female; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Infant; Kidney Failure, Chronic; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Renal Dialysis; Vitamin B 12

2001

Other Studies

268 other study(ies) available for homocysteine and Aging

ArticleYear
Sex-different associations between serum homocysteine, high-sensitivity C-reactive protein and sarcopenia: Results from I-Lan Longitudinal Aging Study.
    Experimental gerontology, 2020, Volume: 132

    Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Female; Hand Strength; Homocysteine; Humans; Logistic Models; Longitudinal Studies; Male; Middle Aged; Risk Factors; Sarcopenia; Sex Characteristics; Walk Test

2020
Genetic Variants of Homocysteine Metabolism, Homocysteine, and Frailty - Rugao Longevity and Ageing Study.
    The journal of nutrition, health & aging, 2020, Volume: 24, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Female; Frailty; Homocysteine; Humans; Longevity; Male; Polymorphism, Genetic

2020
Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Aging; Animals; Autophagy; Cells, Cultured; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Male; Metalloporphyrins; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley

2020
Blood total antioxidant status is associated with cortical glucose uptake and factors related to accelerated aging.
    Brain structure & function, 2020, Volume: 225, Issue:2

    Topics: Aged; Aging; Antioxidants; Brain; Female; Fluorodeoxyglucose F18; Glucose; Homocysteine; Humans; Male; Middle Aged; Oxygen Radical Absorbance Capacity; Positron-Emission Tomography

2020
Dynamics and interactions of cobalamin and folate status during advanced aging - a longitudinal study in a community-dwelling cohort with multiple follow-ups.
    Nutrition journal, 2020, 07-02, Volume: 19, Issue:1

    Topics: Aged; Aging; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Independent Living; Longitudinal Studies; Vitamin B 12

2020
Associations of Plasma Folate and Vitamin B6 With Blood DNA Methylation Age: An Analysis of One-Carbon Metabolites in the VA Normative Aging Study.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2021, 04-30, Volume: 76, Issue:5

    Topics: Aged; Aging; Biomarkers; CpG Islands; DNA Methylation; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Regression Analysis; Veterans; Vitamin B 12; Vitamin B 6

2021
Vitamin B-6 intake is related to physical performance in European older adults: results of the New Dietary Strategies Addressing the Specific Needs of the Elderly Population for Healthy Aging in Europe (NU-AGE) study.
    The American journal of clinical nutrition, 2021, 04-06, Volume: 113, Issue:4

    Topics: Aged; Aging; Diet; Dietary Supplements; Europe; Exercise; Female; Hand Strength; Healthy Aging; Homocysteine; Humans; Male; Nutritional Status; Physical Functional Performance; Vitamin B 6

2021
Total Plasma Homocysteine and Depressive Symptoms in Older Hispanics.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 82, Issue:s1

    Topics: Aged; Aging; Biomarkers; Cohort Studies; Cross-Sectional Studies; Depression; Female; Hispanic or Latino; Homocysteine; Humans; Male; Middle Aged; Venezuela

2021
Plasma homocysteine and macular thickness in older adults-the Rugao Longevity and Aging Study.
    Eye (London, England), 2022, Volume: 36, Issue:5

    Topics: Aged; Aging; Cohort Studies; Cross-Sectional Studies; Female; Homocysteine; Humans; Longevity; Male; Nerve Fibers; Prospective Studies; Retinal Ganglion Cells

2022
[Age-related changes in biogenic amine content and oxidative stress profile in the rat hypothalamus in hyperhomocysteinemia].
    Advances in gerontology = Uspekhi gerontologii, 2016, Volume: 29, Issue:2

    Topics: Aging; Animals; Biogenic Amines; Female; Gonadotropin-Releasing Hormone; Homocysteine; Hyperhomocysteinemia; Hypothalamus; Oxidative Stress; Rats; Rats, Wistar

2016
Tolerance to increased supplemented dietary intakes of methionine in healthy older adults.
    The American journal of clinical nutrition, 2017, Volume: 106, Issue:2

    Topics: Aged; Aging; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Reference Values

2017
Amino acid metabolites, mTORC1 and aging.
    Aging, 2017, Jul-17, Volume: 9, Issue:7

    Topics: Aging; Amino Acids; Animals; Homocysteine; Humans; Mechanistic Target of Rapamycin Complex 1; Up-Regulation

2017
Vitamin B12 and Homocysteine Associations with Gait Speed in Older Adults: The Baltimore Longitudinal Study of Aging.
    The journal of nutrition, health & aging, 2017, Volume: 21, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Baltimore; Female; Folic Acid; Gait; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Middle Aged; Vitamin B 12; Walking Speed

2017
Low-grade systemic inflammation is associated with functional disability in elderly people affected by dementia.
    GeroScience, 2018, Volume: 40, Issue:1

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; C-Reactive Protein; Case-Control Studies; Cognitive Dysfunction; Dementia; Disability Evaluation; Disease Progression; Female; Geriatric Assessment; Homocysteine; Humans; Inflammation; Italy; Male; Reference Values; Retrospective Studies

2018
Demethylation of methionine and keratin damage in human hair.
    Amino acids, 2018, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Copper; Female; Hair; Homocysteine; Humans; Infant; Iron; Keratins; Male; Methionine; Methylation; Middle Aged

2018
Elevated Total Homocysteine in All Participants and Plasma Vitamin B12 Concentrations in Women Are Associated With All-Cause and Cardiovascular Mortality in the Very Old: The Newcastle 85+ Study.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2018, 08-10, Volume: 73, Issue:9

    Topics: Aged, 80 and over; Aging; Biomarkers; Cardiovascular Diseases; Correlation of Data; Demography; Erythrocytes; Female; Folic Acid; Health Status Disparities; Homocysteine; Humans; Male; Risk Assessment; Risk Factors; Sex Factors; Socioeconomic Factors; United Kingdom; Vitamin B 12

2018
Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 64, Issue:1

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Female; Folic Acid; Glycogen Synthase Kinase 3 beta; Homocysteine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Transgenic; Mutation; Phosphorylation

2018
Age-dependent effects of homocysteine and dimethylarginines on cardiovascular mortality in claudicant patients with lower extremity arterial disease.
    Heart and vessels, 2018, Volume: 33, Issue:12

    Topics: Aged; Aging; Arginine; Austria; Cardiovascular Diseases; Female; Homocysteine; Humans; Incidence; Intermittent Claudication; Lower Extremity; Male; Prospective Studies; Risk Factors; Survival Rate

2018
Homocysteine and age-associated disorders.
    Ageing research reviews, 2019, Volume: 49

    Topics: Aged; Aging; Bone Diseases; Chronic Disease; Hearing Loss; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Quality of Life; Renal Insufficiency; Risk Factors

2019
The association between homocysteine levels, Mediterranean diet and cardiovascular disease: a case-control study.
    International journal of food sciences and nutrition, 2019, Volume: 70, Issue:5

    Topics: Acute Coronary Syndrome; Adult; Age Factors; Aged; Aging; Cardiovascular Diseases; Case-Control Studies; Diet, Mediterranean; Female; Homocysteine; Humans; Life Style; Logistic Models; Male; Middle Aged; Regression Analysis; Sex Factors

2019
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study.
    Journal of the American Medical Directors Association, 2019, Volume: 20, Issue:5

    Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Homocysteine; Humans; Ireland; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B Complex

2019
Serum Homocysteine Levels Had Important Associations with Activity and Quality of Daily Living in Chinese Centenarians.
    The journal of nutrition, health & aging, 2019, Volume: 23, Issue:5

    Topics: Activities of Daily Living; Aged, 80 and over; Aging; Asian People; China; Cohort Studies; Female; Homocysteine; Humans; Male; Quality of Life

2019
Homocysteine levels and cognitive function scores measured with MMSE and BCAT of middle-aged and elderly subjects in Tianjin City.
    The journal of nutrition, health & aging, 2013, Volume: 17, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; China; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Intelligence Tests; Linear Models; Male; Middle Aged; Neuropsychological Tests; Prevalence; Sex Factors; Surveys and Questionnaires

2013
Elevated homocysteine levels are associated with low muscle strength and functional limitations in older persons.
    The journal of nutrition, health & aging, 2013, Volume: 17, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Creatinine; Cross-Sectional Studies; Female; Follow-Up Studies; Hand Strength; Homocysteine; Humans; Longitudinal Studies; Male; Muscle Strength; Muscle, Skeletal; Walking

2013
Association between total plasma homocysteine level and cognitive functions in elderly Egyptian subjects.
    Journal of the neurological sciences, 2013, Sep-15, Volume: 332, Issue:1-2

    Topics: Aged; Aging; Basilar Artery; Cognition Disorders; Egypt; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Mental Status Schedule; Neuropsychological Tests; Vertebral Artery

2013
Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice.
    The Journal of nutrition, 2013, Volume: 143, Issue:10

    Topics: Age Factors; Aging; Animals; Bifidobacterium; Feces; Homocysteine; Intestines; Lactobacillus acidophilus; Magnetic Resonance Spectroscopy; Male; Metabolic Networks and Pathways; Metabolome; Mice; Mice, Inbred BALB C; NAD; Niacin; Niacinamide; Pentanoic Acids; Phenylacetates; Probiotics; Sarcosine; Xylose

2013
Methylenetetrahydrofolate reductase 677 genotype-specific reference values for plasma homocysteine and serum folate concentrations in korean population aged 45 to 74 years: the Namwon study.
    Journal of Korean medical science, 2014, Volume: 29, Issue:5

    Topics: Age Factors; Aged; Aging; Cohort Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Reference Values; Republic of Korea; Sex Factors

2014
Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals.
    The American journal of clinical nutrition, 2014, Volume: 100, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Randomized Controlled Trials as Topic; Vitamin B Complex

2014
B12 deficiency increases with age in hospitalized patients: a study on 14,904 samples.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2014, Volume: 69, Issue:12

    Topics: Adolescent; Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aging; Female; Follow-Up Studies; Hemoglobins; Homocysteine; Humans; Inpatients; Male; Middle Aged; Morbidity; Paris; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2014
Homocysteine and cytosolic GSH depletion induce apoptosis and oxidative toxicity through cytosolic calcium overload in the hippocampus of aged mice: involvement of TRPM2 and TRPV1 channels.
    Neuroscience, 2015, Jan-22, Volume: 284

    Topics: Aging; Animals; Antimetabolites; Apoptosis; Buthionine Sulfoximine; Calcium; Capsaicin; Cells, Cultured; Cytosol; Glutathione; Hippocampus; Homocysteine; Hydrogen Peroxide; Male; Mice, Inbred C57BL; Neurons; Oxidative Stress; TRPM Cation Channels; TRPV Cation Channels

2015
Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress.
    European journal of clinical nutrition, 2015, Volume: 69, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Alcohol Drinking; Connecticut; Diabetes Mellitus; Dietary Supplements; Female; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Neurocognitive Disorders; Oxidative Stress; Primary Health Care; Renal Insufficiency; Retrospective Studies; Risk Factors; Smoking; Vitamin B 12; Vitamin B 12 Deficiency

2015
Age dependent levels of plasma homocysteine and cognitive performance.
    Behavioural brain research, 2015, Apr-15, Volume: 283

    Topics: Adolescent; Adult; Aged; Aging; Attention; C-Reactive Protein; Cognition; Depression; Female; Folic Acid; Homocysteine; Humans; India; Interleukin-6; Male; Mental Recall; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Surveys and Questionnaires; Vitamin B 12; Young Adult

2015
B-vitamin trials meta-analysis: less than meets the eye.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:2

    Topics: Aging; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex

2015
Homocysteine lowering, B vitamins, and cognitive aging.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:2

    Topics: Aging; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex

2015
Reply to Garrard and Jacoby and Smith et al.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:2

    Topics: Aging; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex

2015
Opioid-induced Respiratory Depression Is Only Partially Mediated by the preBötzinger Complex in Young and Adult Rabbits In Vivo.
    Anesthesiology, 2015, Volume: 122, Issue:6

    Topics: Aging; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Homocysteine; Male; Naloxone; Narcotic Antagonists; Neurons; Rabbits; Respiratory Insufficiency

2015
Vitamin B12 and folate levels in healthy Swiss senior citizens: a prospective study evaluating reference intervals and decision limits.
    BMC geriatrics, 2015, Jul-11, Volume: 15

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Erythrocyte Count; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Reference Values; ROC Curve; Sex Factors; Switzerland; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency

2015
Causes of Thickening of Carotid Intima-Media Thickness in Patients With Alcoholic Liver Disease: A Prospective Observational Study.
    Medicine, 2015, Volume: 94, Issue:28

    Topics: Aging; Blood Glucose; Body Mass Index; Carotid Arteries; Carotid Intima-Media Thickness; Cytokines; Female; Homocysteine; Humans; Lipids; Liver Diseases, Alcoholic; Male; Oxidative Stress; Prospective Studies; Tunica Intima; Uric Acid

2015
Increased levels of plasma amyloid-beta are related to cortical thinning and cognitive decline in cognitively normal elderly subjects.
    Neurobiology of aging, 2015, Volume: 36, Issue:10

    Topics: Aged; Aging; Alzheimer Disease; Amyloid beta-Peptides; Cerebral Cortex; Cognition; Cognition Disorders; Female; Homocysteine; Humans; Male; Peptide Fragments; Risk Factors

2015
Associations of Polymorphisms in MTHFR Gene with the Risk of Age-Related Cataract in Chinese Han Population: A Genotype-Phenotype Analysis.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Asian People; Case-Control Studies; Cataract; Female; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6

2015
High homocysteine and epistasis between MTHFR and APOE: association with cognitive performance in the elderly.
    Experimental gerontology, 2016, Volume: 76

    Topics: Age Factors; Aged; Aging; Apolipoproteins E; Biomarkers; Cognition; Cognition Disorders; Cross-Sectional Studies; Epistasis, Genetic; Executive Function; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Phenotype; Polymorphism, Genetic; Principal Component Analysis; Risk Factors; Up-Regulation

2016
Association between leukocyte telomere length and serum carotenoid in US adults.
    European journal of nutrition, 2017, Volume: 56, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Body Mass Index; Carotenoids; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Folic Acid; Homocysteine; Humans; Leukocytes; Logistic Models; Male; Middle Aged; Nutrition Surveys; Socioeconomic Factors; Telomere; Young Adult

2017
Greater loss in muscle mass and function but smaller metabolic alterations in older compared with younger men following 2 wk of bed rest and recovery.
    Journal of applied physiology (Bethesda, Md. : 1985), 2016, Apr-15, Volume: 120, Issue:8

    Topics: Adult; Aging; Bed Rest; Homocysteine; Humans; Insulin Resistance; Lipids; Male; Middle Aged; Muscle Fibers, Skeletal; Young Adult

2016
Homocysteine and Real-Space Navigation Performance among Non-Demented Older Adults.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 55, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Auditory Perception; Case-Control Studies; Cognitive Dysfunction; Discrimination, Psychological; Female; Homocysteine; Humans; Male; Maze Learning; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Spatial Navigation

2017
DNA methylation patterns associated with oxidative stress in an ageing population.
    BMC medical genomics, 2016, 11-25, Volume: 9, Issue:1

    Topics: Aging; Biomarkers; CpG Islands; DNA Methylation; Glutathione; Homocysteine; Humans; Oxidative Stress

2016
Increased Coagulation With Aging: Importance of Homocysteine and Vitamin B12.
    Circulation journal : official journal of the Japanese Circulation Society, 2017, Jan-25, Volume: 81, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Atrial Fibrillation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Thrombophilia; Vitamin B 12

2017
Increased Coagulation With Aging: Importance of Homocysteine and Vitamin B12 - Reply.
    Circulation journal : official journal of the Japanese Circulation Society, 2017, Jan-25, Volume: 81, Issue:2

    Topics: Aging; Homocysteine; Humans; Hyperhomocysteinemia; Thrombophilia; Vitamin B 12

2017
Vitamin B
    European journal of clinical nutrition, 2017, Volume: 71, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Incidence; Linear Models; Longitudinal Studies; Male; Multivariate Analysis; Netherlands; Proportional Hazards Models; Prospective Studies; Vitamin B 12

2017
[Clinical evaluation of serum albumin reductivity in patients with renal dysfunction: a comparison between conservative renal failure patients and hemodialysis patients].
    Nihon Jinzo Gakkai shi, 2008, Volume: 50, Issue:4

    Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Cysteine; Female; Gas Chromatography-Mass Spectrometry; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Oxidation-Reduction; Renal Dialysis; Renal Insufficiency; Serum Albumin

2008
Detection of altered global DNA methylation in coronary artery disease patients.
    DNA and cell biology, 2008, Volume: 27, Issue:7

    Topics: Adult; Aged; Aging; Apolipoproteins E; Case-Control Studies; Chromosome Mapping; Cohort Studies; Coronary Artery Disease; Diet; DNA Methylation; Genome, Human; Homocysteine; Humans; Middle Aged

2008
Cysteinylation and homocysteinylation of plasma protein thiols during ageing of healthy human beings.
    Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:9B

    Topics: Adult; Aged; Aged, 80 and over; Aging; Antioxidants; Chromatography, High Pressure Liquid; Cysteine; Female; Homocysteine; Humans; Male; Middle Aged; Oxidative Stress; Risk; Sulfhydryl Compounds

2009
Vascular biomarkers of cognitive performance in a community-based elderly population: the Dublin Healthy Ageing study.
    Age and ageing, 2008, Volume: 37, Issue:5

    Topics: Activities of Daily Living; Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Cognition; Cross-Sectional Studies; Female; Homocysteine; Humans; Ireland; Life Style; Male; Memory; Mental Recall; Neuropsychological Tests; Population Surveillance; Up-Regulation; Vascular Diseases; Verbal Learning

2008
Serum homocysteine: relationship with circulating levels of cortisol and ascorbate.
    Annals of nutrition & metabolism, 2008, Volume: 53, Issue:1

    Topics: Aging; Ascorbic Acid; Cardiovascular Diseases; Female; Folic Acid; Health Status; Homocysteine; Humans; Hydrocortisone; Linear Models; Male; Middle Aged; Nutritional Status; Risk Factors

2008
C-reactive protein: vascular risk marker in elderly patients with mental illness.
    Dementia and geriatric cognitive disorders, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; C-Reactive Protein; Cerebrovascular Disorders; Cognition Disorders; Cystatin C; Depression; Female; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Risk Factors

2008
Higher folate intake is related to lower risk of Alzheimer's disease in the elderly.
    The journal of nutrition, health & aging, 2008, Volume: 12, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Male; Nutrition Assessment; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2008
Homocysteine and inflammation: predictors of cognitive decline in older persons?
    Neurobiology of aging, 2010, Volume: 31, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; alpha 1-Antichymotrypsin; Biomarkers; C-Reactive Protein; Cognition; Cognition Disorders; Homocysteine; Humans; Interleukin-6; Longitudinal Studies; Male; Neuropsychological Tests; Risk Factors

2010
Genetic variation in homocysteine metabolism, cognition, and white matter lesions.
    Neurobiology of aging, 2010, Volume: 31, Issue:11

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Aged, 80 and over; Aging; Brain; Cognition; Cross-Sectional Studies; Cystathionine beta-Synthase; Ferredoxin-NADP Reductase; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nerve Fibers, Myelinated; Reduced Folate Carrier Protein; Transcobalamins

2010
Homocysteine and inflammation as main determinants of oxidative stress in the elderly.
    Free radical biology & medicine, 2009, Mar-15, Volume: 46, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; C-Reactive Protein; Cell Line; Enzyme Activation; Female; Homocysteine; Humans; Inflammation; Lipid Metabolism; Male; Monocytes; NADPH Oxidases; Nutrition Assessment; Oxidative Stress; Prealbumin; Superoxides

2009
Do dietary patterns in older men influence change in homocysteine through folate fortification? The Normative Aging Study.
    Public health nutrition, 2009, Volume: 12, Issue:10

    Topics: Aged; Aging; Alcohol Drinking; Boston; Cluster Analysis; Diet; Dietary Supplements; Folic Acid; Food, Fortified; Fruit; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Vegetables; Vitamin B Complex

2009
Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency.
    The American journal of clinical nutrition, 2009, Volume: 89, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Anemia, Pernicious; Cognition Disorders; Drug Interactions; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Middle Aged; Nutrition Surveys; Nutritional Status; Odds Ratio; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency

2009
Decreased serum paraoxonase 1 activity and increased serum homocysteine and malondialdehyde levels in age-related macular degeneration.
    The Tohoku journal of experimental medicine, 2009, Volume: 217, Issue:1

    Topics: Age Distribution; Aged; Aging; Aryldialkylphosphatase; Female; Homocysteine; Humans; Macular Degeneration; Male; Malondialdehyde; Middle Aged

2009
Plasma homocysteine levels and different forms of vascular disease in patients with dementia and other psychogeriatric diseases.
    Dementia and geriatric cognitive disorders, 2009, Volume: 27, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Creatinine; Dementia; Female; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Vascular Diseases

2009
Dietary sources of vitamin B-12 and their association with plasma vitamin B-12 concentrations in the general population: the Hordaland Homocysteine Study.
    The American journal of clinical nutrition, 2009, Volume: 89, Issue:4

    Topics: Aged; Aging; Biological Availability; Cross-Sectional Studies; Dairy Products; Diet; Diet Surveys; Female; Homocysteine; Humans; Male; Middle Aged; Norway; Nutritional Requirements; Nutritional Status; Seafood; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2009
Cerebral white matter lesions in patients with dementia - from MCI to severe Alzheimer's disease.
    Journal of the neurological sciences, 2009, Aug-15, Volume: 283, Issue:1-2

    Topics: Aged; Aging; Alzheimer Disease; Brain; Cognition Disorders; Disease Progression; Female; Homocysteine; Humans; Hypertension; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated

2009
Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats.
    Brain research, 2009, Jun-01, Volume: 1273

    Topics: Aging; Animals; Brain; Convulsants; Cytoprotection; Drug Administration Schedule; Drug Interactions; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Homocysteine; Male; Nerve Degeneration; Neuroprotective Agents; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus; Treatment Outcome

2009
Midlife homocysteine and late-life dementia in women. A prospective population study.
    Neurobiology of aging, 2011, Volume: 32, Issue:3

    Topics: Adult; Aging; Community Health Planning; Confidence Intervals; Dementia; Female; Homocysteine; Humans; Longitudinal Studies; Middle Aged; Neurologic Examination; Proportional Hazards Models; Psychiatric Status Rating Scales; Retrospective Studies; Survival Analysis

2011
High-dose short-term folate administration modifies ambulatory blood pressure in postmenopausal women. A placebo-controlled study.
    European journal of clinical nutrition, 2009, Volume: 63, Issue:10

    Topics: Aging; Blood Pressure; Cardiovascular Diseases; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin; Middle Aged; Postmenopause; Vitamin B Complex

2009
Ontogeny of methionine utilization and splanchnic uptake in critically ill children.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:5

    Topics: Abdomen; Adolescent; Aging; Algorithms; Carbon Dioxide; Child; Child, Preschool; Critical Illness; Diet; Enteral Nutrition; Female; Homocysteine; Humans; Infant; Isotope Labeling; Kinetics; Male; Methionine; Oxidation-Reduction

2009
A cross-sectional study of familial clustering in hyperhomocysteinemia.
    Gerontology, 2010, Volume: 56, Issue:1

    Topics: Aged; Aging; Asian People; Cluster Analysis; Cross-Sectional Studies; Family Health; Female; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Male; Middle Aged; Prevalence; Risk Factors

2010
Telomere length in lymphocytes of older South Australian men may be inversely associated with plasma homocysteine.
    Rejuvenation research, 2009, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Australia; Chromosome Aberrations; Cohort Studies; Female; Homocysteine; Humans; Lymphocytes; Male; Middle Aged; Telomere

2009
The associations between blood levels of homocysteine, folate, vitamin B12, and retinal vascular caliber.
    American journal of ophthalmology, 2009, Volume: 148, Issue:6

    Topics: Aged; Aging; Arterioles; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Photography; Retinal Artery; Retinal Vein; Sex Factors; Smoking; Venules; Vitamin B 12

2009
Folic acid, vitamin B12, and homocysteine levels during fasting and after methionine load in patients with Type 1 diabetes mellitus.
    Journal of endocrinological investigation, 2010, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Aging; Blood Glucose; Case-Control Studies; Child; Diabetes Mellitus, Type 1; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Sex Characteristics; Vitamin B 12; Young Adult

2010
Redox homeostasis and cellular stress response in aging and neurodegeneration.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 610

    Topics: Acetylcarnitine; Aging; Animals; Carbon Monoxide; Gene Regulatory Networks; Heme Oxygenase-1; Homeostasis; Homocysteine; HSP70 Heat-Shock Proteins; Humans; Nerve Degeneration; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Stress, Physiological

2010
Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes.
    Experimental gerontology, 2010, Volume: 45, Issue:4

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aging; Autoimmune Diseases; CD27 Ligand; CD28 Antigens; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Modification Methylases; Female; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Male; Methionine; Micronutrients; Middle Aged; Receptors, KIR; T-Lymphocytes

2010
Relationship of asymmetric dimethylarginine and homocysteine to vascular aging in systemic lupus erythematosus patients.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:6

    Topics: Adult; Aging; Arginine; Carotid Arteries; Female; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Multivariate Analysis; Patient Selection; Prognosis; Severity of Illness Index; Vascular Diseases

2010
Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics.
    European journal of clinical nutrition, 2010, Volume: 64, Issue:5

    Topics: Aged; Aging; Analysis of Variance; California; Female; Genotype; Health Surveys; Hispanic or Latino; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B Complex; White People

2010
Effects of selaginellin on homocysteine-induced senescence in human umbilical vein endothelial cells.
    Journal of cardiovascular pharmacology, 2010, Volume: 55, Issue:6

    Topics: Aging; Antioxidants; beta-Galactosidase; Cell Cycle; Cellular Senescence; Down-Regulation; Endothelial Cells; Endothelium; Homocysteine; Humans; Nitric Oxide Synthase Type III; Reactive Oxygen Species; Umbilical Veins; Up-Regulation

2010
Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:6

    Topics: Aged; Aging; Anemia; Anemia, Macrocytic; Blood Cell Count; Cognition; Cognition Disorders; Cystatin C; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Multivariate Analysis; Nutrition Surveys; Tetrahydrofolates; United States; Vitamin B 12 Deficiency

2010
Vitamin B12 deficiency in African American and white octogenarians and centenarians in Georgia.
    The journal of nutrition, health & aging, 2010, Volume: 14, Issue:5

    Topics: Age Factors; Aged, 80 and over; Aging; Black or African American; Erythrocytes; Female; Folic Acid; Georgia; Homocysteine; Humans; Male; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency; White People

2010
Determinants of white matter hyperintensity volume in patients with acute ischemic stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2010, Volume: 19, Issue:3

    Topics: Adult; Aged; Aging; Biomarkers; Brain; Brain Ischemia; Cohort Studies; Coronary Artery Disease; Female; Homocysteine; Humans; Hypertension; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neurologic Examination; Retrospective Studies; Risk Factors; Stroke

2010
Serum homocysteine and folate concentrations are associated with prevalent age-related hearing loss.
    The Journal of nutrition, 2010, Volume: 140, Issue:8

    Topics: Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Female; Folic Acid; Health Surveys; Hearing Loss; Homocysteine; Humans; Male; Multivariate Analysis; Odds Ratio; Vitamin B 12

2010
Age, homocysteine, and oxidative stress: relation to hypertension and type 2 diabetes mellitus.
    Journal of the American College of Nutrition, 2010, Volume: 29, Issue:1

    Topics: Adult; Age Factors; Aged; Aging; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hypertension; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Reactive Oxygen Species

2010
Polymorphism of MTHFR C677T, serum vitamin levels and cognition in subjects with hyperhomocysteinemia in China.
    Nutritional neuroscience, 2010, Volume: 13, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6; Vitamins

2010
Aging and antioxidants modulate rat brain levels of homocysteine and dehydroepiandrosterone sulphate (DHEA-S): implications in the pathogenesis of Alzheimer's disease.
    Neuroscience letters, 2010, Oct-11, Volume: 483, Issue:2

    Topics: Aging; Alzheimer Disease; Animals; Antioxidants; Brain; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Homocysteine; Rats; Rats, Wistar

2010
Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal study.
    Neurology, 2010, Oct-19, Volume: 75, Issue:16

    Topics: Aged; Aging; Alzheimer Disease; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Dementia; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Mental Status Schedule; Odds Ratio; Risk Factors; Transcobalamins

2010
Effect of antioxidant vitamins on the plasma homocysteine level in a free-living elderly population.
    Annals of nutrition & metabolism, 2010, Volume: 57, Issue:3-4

    Topics: Aged; Aging; Antioxidants; Ascorbic Acid; beta Carotene; Cardiovascular Diseases; Cross-Sectional Studies; Female; Folic Acid; Germany; Glomerular Filtration Rate; Homocysteine; Humans; Longitudinal Studies; Male; Vitamin E; Vitamins

2010
Polyneuropathy and dementia in old age: common inflammatory and vascular parameters.
    Journal of neural transmission (Vienna, Austria : 1996), 2011, Volume: 118, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Cohort Studies; Dementia; Female; Folic Acid; Geriatrics; Homocysteine; Humans; Inflammation; Male; Mental Status Schedule; Neopterin; Neural Conduction; Polyneuropathies; Sural Nerve; Vascular Diseases; Vitamin B 12

2011
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and cognitive impairment: the health in men study.
    Molecular psychiatry, 2012, Volume: 17, Issue:5

    Topics: Aged, 80 and over; Aging; Case-Control Studies; Cognition Disorders; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Men's Health; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide

2012
Do the effects of APOE-ε4 on cognitive function and decline depend upon vitamin status? MacArthur Studies of Successful Aging.
    The journal of nutrition, health & aging, 2011, Volume: 15, Issue:3

    Topics: Aged; Aging; Apolipoprotein E4; Cognition; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Longitudinal Studies; Male; Nutrigenomics; Nutritional Status; United States; Vitamin B Complex

2011
Serum folate is significantly correlated with plasma cysteine concentrations in healthy industry workers.
    Annals of nutrition & metabolism, 2011, Volume: 58, Issue:1

    Topics: Adult; Aged; Aging; Cardiovascular Diseases; Cysteine; Extraction and Processing Industry; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Norway; Risk Factors; Triglycerides; Young Adult

2011
Plasma homocysteine and cognitive decline in older hypertensive subjects.
    International psychogeriatrics, 2011, Volume: 23, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Cognition; Cognition Disorders; Executive Function; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hypertension; Male; Neuropsychological Tests; Risk Factors; Vitamin B 12

2011
Cortisol levels and metabolic parameters in middle- and advanced- age subjects: associations with age.
    Journal of endocrinological investigation, 2011, Volume: 34, Issue:11

    Topics: Aged; Aged, 80 and over; Aging; Blood Glucose; Body Mass Index; Cohort Studies; Cross-Sectional Studies; Female; Greece; Homocysteine; Humans; Hydrocortisone; Insulin; Male; Middle Aged; Waist-Hip Ratio

2011
Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study.
    Journal of Alzheimer's disease : JAD, 2011, Volume: 27, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; Australia; Brain; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Vitamin B 12

2011
Arterial function of carotid and brachial arteries in postmenopausal vegetarians.
    Vascular health and risk management, 2011, Volume: 7

    Topics: Age Factors; Aging; Biomarkers; Blood Glucose; Brachial Artery; C-Reactive Protein; Carotid Artery, Common; Chi-Square Distribution; Compliance; Cross-Sectional Studies; Diet, Vegetarian; Female; Homocysteine; Humans; Linear Models; Lipids; Lipoprotein(a); Middle Aged; Postmenopause; Pulsatile Flow; Taiwan; Ultrasonography, Doppler, Pulsed; Vascular Resistance; Vitamin B 12

2011
Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia.
    Experimental eye research, 2012, Volume: 96, Issue:1

    Topics: Aging; Animals; Cystathionine beta-Synthase; Dark Adaptation; Disease Models, Animal; Electroretinography; Evoked Potentials, Visual; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Retina; Retinal Pigment Epithelium; Visual Acuity; Visual Cortex

2012
Ageing in Werner syndrome.
    Bioscience trends, 2012, Volume: 6, Issue:1

    Topics: Adult; Aged, 80 and over; Aging; Arginine; Female; Health; Homocysteine; Humans; Lysine; Male; Middle Aged; Werner Syndrome

2012
Relationships among biomarkers of one-carbon metabolism.
    Molecular biology reports, 2012, Volume: 39, Issue:7

    Topics: Adult; Aging; Biomarkers; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Vitamin B 12; Young Adult

2012
Mitochondrial DNA copy number in peripheral blood is associated with femoral neck bone mineral density in postmenopausal women.
    The Journal of rheumatology, 2012, Volume: 39, Issue:7

    Topics: Absorptiometry, Photon; Adiponectin; Aging; Blood Pressure; Body Mass Index; Bone Density; C-Reactive Protein; DNA, Mitochondrial; Exercise; Female; Femur Neck; Homocysteine; Humans; Lipids; Middle Aged; Osteocalcin; Osteoporosis, Postmenopausal; Vitamin D; Waist Circumference

2012
Unmetabolized folic acid prevalence is widespread in the older Irish population despite the lack of a mandatory fortification program.
    The American journal of clinical nutrition, 2012, Volume: 96, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Cohort Studies; Cross-Sectional Studies; Diet; Erythrocytes; Female; Folic Acid; Food, Fortified; Health Promotion; Homocysteine; Humans; Ireland; Male; Middle Aged; Nutrition Policy; Vitamin B 12; Vitamin B 12 Deficiency; Voluntary Programs

2012
Homocysteine, progression of ventricular enlargement, and cognitive decline: the Second Manifestations of ARTerial disease-Magnetic Resonance study.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2013, Volume: 9, Issue:3

    Topics: Aged; Aging; Atherosclerosis; Atrophy; Biomarkers; Cerebral Infarction; Cerebral Ventricles; Cognition Disorders; Disease Progression; Executive Function; Female; Homocysteine; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Risk Factors

2013
Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid.
    Clinical chemistry and laboratory medicine, 2012, Mar-24, Volume: 50, Issue:9

    Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Vitamin B 12

2012
Age-related cataracts: homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection.
    Chemico-biological interactions, 2012, Oct-25, Volume: 200, Issue:1

    Topics: Active Transport, Cell Nucleus; Aging; Animals; Antioxidants; Cataract; Cattle; Cell Death; Cell Nucleus; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Homocysteine; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Time Factors; Unfolded Protein Response

2012
Elevated plasma homocysteine level is not primarily related to Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2012, Volume: 34, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency

2012
Homocysteine, folate, vitamin B-12, and physical function in older adults: cross-sectional findings from the Singapore Longitudinal Ageing Study.
    The American journal of clinical nutrition, 2012, Volume: 96, Issue:6

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Gait; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Middle Aged; Mobility Limitation; Postural Balance; Prospective Studies; Singapore; Vitamin B 12; Vitamin B 12 Deficiency

2012
Plasma homocysteine levels increase following stress in older but not younger men.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:8

    Topics: Adult; Aged; Aging; Homocysteine; Humans; Hydrocortisone; Male; Middle Aged; Saliva; Stress, Psychological

2013
Transsulfuration pathway thiols and methylated arginines: the Hunter Community Study.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aging; Amidohydrolases; Arginine; Australia; C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Community Medicine; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Taurine

2013
Paradigm of vascular aging: conceptual strides slowed by technical limitations.
    Journal of the American Geriatrics Society, 2002, Volume: 50, Issue:6

    Topics: Aging; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Endothelium, Vascular; Exercise; Homocysteine; Humans

2002
Interaction of excitatory amino acid agonists with cortical afterdischarges in developing rats.
    Epilepsia, 2002, Volume: 43 Suppl 5

    Topics: Aging; Animals; Cerebral Cortex; Electric Stimulation; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Homocysteine; Kainic Acid; N-Methylaspartate; Rats; Rats, Wistar

2002
Influence of age, sex and vitamin status on fasting and post-methionine load plasma homocysteine levels.
    Haematologica, 2002, Volume: 87, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Fasting; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Sex Characteristics; Time Factors; Vitamins

2002
Effects of pinealectomy on the levels and the circadian rhythm of plasma homocysteine in rats.
    Journal of pineal research, 2002, Volume: 33, Issue:3

    Topics: Aged; Aging; Animals; Circadian Rhythm; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pineal Gland; Rats; Risk Factors

2002
Elevated serum methylmalonic acid concentrations are common among elderly Americans.
    The Journal of nutrition, 2002, Volume: 132, Issue:9

    Topics: Adult; Aged; Aging; Black or African American; Creatinine; Female; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Vitamin B 12; Vitamin B 12 Deficiency; White People

2002
Homocysteine, stroke, and dementia.
    Stroke, 2002, Volume: 33, Issue:10

    Topics: Aging; Alzheimer Disease; Causality; Comorbidity; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Vitamin B Complex

2002
Plasma homocysteine and malondialdehyde are correlated in an age- and gender-specific manner.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:11

    Topics: Adult; Age Factors; Aged; Aging; Biomarkers; Female; Homocysteine; Humans; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Reference Values; Risk Factors; Sex Characteristics; Sex Factors; Vascular Diseases

2002
Homocysteine and cognitive function in the elderly: the Rotterdam Scan Study.
    Neurology, 2002, Nov-12, Volume: 59, Issue:9

    Topics: Aged; Aging; Atrophy; Brain; Cognition; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Psychomotor Performance

2002
Minimal hippocampal width relates to plasma homocysteine in community-dwelling older people.
    Age and ageing, 2002, Volume: 31, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Atrophy; Cluster Analysis; Female; Geriatric Assessment; Hippocampus; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Residence Characteristics

2002
Homocysteine, cardiovascular disease risk factors, and habitual diet in the French Supplementation with Antioxidant Vitamins and Minerals Study.
    The American journal of clinical nutrition, 2002, Volume: 76, Issue:6

    Topics: Adult; Aging; Alcohol Drinking; Antioxidants; Apolipoproteins B; Blood Glucose; Body Constitution; Body Mass Index; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Coffee; Dietary Fiber; Dietary Supplements; Energy Intake; Erythrocytes; Exercise; Fasting; Female; Folic Acid; France; Homocysteine; Humans; Male; Middle Aged; Minerals; Risk Factors; Sex Characteristics; Triglycerides; Vitamin B 12; Vitamin B 6; Vitamins

2002
Homocysteine levels and decline in physical function: MacArthur Studies of Successful Aging.
    The American journal of medicine, 2002, Volume: 113, Issue:7

    Topics: Aged; Aging; Biomarkers; Female; Gait; Homocysteine; Humans; Linear Models; Male; Motor Skills; Muscle Contraction; Odds Ratio; Postural Balance; Prospective Studies; Psychomotor Performance; Risk

2002
Can homocysteine be related to physical functioning?
    The American journal of medicine, 2002, Volume: 113, Issue:7

    Topics: Aged; Aging; Folic Acid; Homocysteine; Humans; Psychomotor Performance; Vitamin B 12; Vitamin B 6

2002
Feeding the aging brain.
    Newsweek, 2003, Jan-20, Volume: 141, Issue:3

    Topics: Aging; Alzheimer Disease; Antioxidants; Brain; Cholesterol; Diet; Dietary Fats; Exercise; Fish Oils; Homocysteine; Humans; Hypertension; United States

2003
Homocysteine and cognitive function in healthy elderly community dwellers in Italy.
    The American journal of clinical nutrition, 2003, Volume: 77, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Dementia; Educational Status; Female; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Life Style; Male; Neuropsychological Tests; Odds Ratio; Risk Factors; Socioeconomic Factors

2003
Will caloric restriction and folate protect against AD and PD?
    Neurology, 2003, Feb-25, Volume: 60, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Animals; Brain; Brain-Derived Neurotrophic Factor; Caloric Restriction; Disease Models, Animal; Energy Intake; Folic Acid; Homocysteine; Humans; Middle Aged; Neurons; Oxidative Stress; Parkinson Disease; Rats; Risk Factors

2003
Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE).
    American journal of hematology, 2003, Volume: 72, Issue:3

    Topics: Aged; Aging; Animals; Case-Control Studies; Cohort Studies; Factor V; Female; Genotype; Homocysteine; Humans; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Risk Factors; Venous Thrombosis

2003
[Serum markers in relation to cognitive functioning in an aging population: results of the Maastricht Aging Study (MAAS)].
    Tijdschrift voor gerontologie en geriatrie, 2003, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Biomarkers; C-Reactive Protein; Cholesterol; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Haptoglobins; Homocysteine; Humans; Lanosterol; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Psychomotor Performance

2003
Demographic, health, lifestyle, and blood vitamin determinants of serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey, 1988-1994.
    The American journal of clinical nutrition, 2003, Volume: 77, Issue:4

    Topics: Adult; Aged; Aging; Alcohol Drinking; Alcoholic Beverages; Beer; Black People; Body Mass Index; Cotinine; Dietary Supplements; Erythrocytes; Female; Folic Acid; Health Status; Hispanic or Latino; Homocysteine; Humans; Life Style; Linear Models; Male; Middle Aged; Nutrition Surveys; Sex Characteristics; Vitamin B 12; Vitamins; White People; Wine

2003
Folate deficiency is a common finding in psychogeriatric patients.
    Aging clinical and experimental research, 2002, Volume: 14, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Regression Analysis; Vitamin B 12

2002
Prevalence and mechanisms of hyperhomocysteinemia in elderly hospitalized patients.
    The journal of nutrition, health & aging, 2003, Volume: 7, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutritional Status; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency

2003
Homocysteine: a marker for cognitive performance? A longitudinal follow-up study.
    The journal of nutrition, health & aging, 2003, Volume: 7, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Cognition; Cognition Disorders; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Psychomotor Performance; Risk Factors; Vitamin B 12

2003
Plasma total homocysteine levels, dietary vitamin B6 and folate intake in AD and healthy aging.
    The journal of nutrition, health & aging, 2003, Volume: 7, Issue:3

    Topics: Adult; Aging; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Cholesterol; Educational Status; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Serum Albumin; Smoking; Triglycerides; Vitamin B 6

2003
Age differences in allostatic load: an index of physiological dysregulation.
    Experimental gerontology, 2003, Volume: 38, Issue:7

    Topics: Adaptation, Physiological; Adult; Aging; Biomarkers; Body Mass Index; C-Reactive Protein; Creatinine; Cross-Sectional Studies; Fibrinogen; Health Status Indicators; Health Surveys; Homocysteine; Humans; Hypertension; Middle Aged; Peak Expiratory Flow Rate; Risk Factors; Selection Bias; Serum Albumin; Stress, Physiological; United States

2003
Hyperhomocystinemia in children with inflammatory bowel disease.
    Journal of pediatric gastroenterology and nutrition, 2003, Volume: 37, Issue:5

    Topics: Adolescent; Aging; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Tetrahydrofolates; Thromboembolism; Vitamin B 12; von Willebrand Factor

2003
Functional vitamin B12 deficiency and determination of holotranscobalamin in populations at risk.
    Clinical chemistry and laboratory medicine, 2003, Volume: 41, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Diet, Vegetarian; Female; Folic Acid; Germany; Homocysteine; Humans; Kidney Diseases; Male; Methylmalonic Acid; Middle Aged; Risk; Syria; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency

2003
Association of plasma homocysteine in elderly persons with atherosclerotic vascular disease and dementia, atherosclerotic vascular disease without dementia, dementia without atherosclerotic vascular disease, and no dementia or atherosclerotic vascular dis
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2003, Volume: 58, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Arteriosclerosis; Biomarkers; Case-Control Studies; Cohort Studies; Dementia; Female; Geriatric Assessment; Homes for the Aged; Homocysteine; Humans; Male; Middle Aged; Nursing Homes; Probability; Prognosis; Reference Values; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Vascular Diseases

2003
Plasma total homocysteine levels and cranial magnetic resonance imaging findings in elderly persons: the Cardiovascular Health Study.
    Archives of neurology, 2004, Volume: 61, Issue:1

    Topics: Aged; Aging; Brain; Brain Infarction; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Odds Ratio; Radiography; Risk Factors

2004
Differences in the metabolic response to exogenous homocysteine in juvenile and adult rabbits.
    The Journal of nutritional biochemistry, 2004, Volume: 15, Issue:2

    Topics: Aging; Animals; Disease Models, Animal; Fatty Acids; Folic Acid; Glutathione; Homocysteine; Lipid Peroxidation; Liver; Metabolic Clearance Rate; Rabbits; Thiobarbituric Acid Reactive Substances

2004
Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in Hispanic and non-Hispanic white elders.
    The Journal of nutrition, 2004, Volume: 134, Issue:4

    Topics: Aged; Aging; C-Reactive Protein; Diet; Female; Fruit; Hispanic or Latino; Homocysteine; Humans; Male; Massachusetts; Odds Ratio; Vegetables

2004
Effects of paradoxical sleep deprivation on blood parameters associated with cardiovascular risk in aged rats.
    Experimental gerontology, 2004, Volume: 39, Issue:5

    Topics: Age Factors; Aging; Animals; Blood Viscosity; Cardiovascular Diseases; Cholesterol; Folic Acid; Homocysteine; Lipoproteins; Male; Rats; Rats, Wistar; Risk Factors; Sleep Deprivation; Triglycerides; Vitamin B 12

2004
Improved rotorod performance and hyperactivity in mice deficient in a protein repair methyltransferase.
    Behavioural brain research, 2004, Aug-12, Volume: 153, Issue:1

    Topics: Age Factors; Aging; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Diet, Reducing; Exploratory Behavior; Genotype; Homocysteine; Hyperkinesis; Mice; Mice, Knockout; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rotarod Performance Test; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereotyped Behavior; Survival Rate; Time Factors

2004
Effect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and different lifestyle factors.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2004, Volume: 74, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Female; Folic Acid; Germany; Homocysteine; Humans; Life Style; Linear Models; Longitudinal Studies; Male; Methionine; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Sex Characteristics; Smoking; Tea; Vitamin B 12

2004
Increasing production of homocysteine and neopterin and degradation of tryptophan with older age.
    Clinical biochemistry, 2004, Volume: 37, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aging; Dioxygenases; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Macrophages; Male; Middle Aged; Neopterin; T-Lymphocytes; Time Factors; Tryptophan; Vitamin B 12

2004
Homocysteine as a predictive factor for hip fracture in older persons.
    The New England journal of medicine, 2004, Sep-02, Volume: 351, Issue:10

    Topics: Aged; Aging; Creatinine; Glomerular Filtration Rate; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors

2004
Homocysteine as a predictive factor for hip fracture in older persons.
    The New England journal of medicine, 2004, Sep-02, Volume: 351, Issue:10

    Topics: Aged; Aging; Bone Density; Folic Acid Deficiency; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors; Vitamin B Deficiency

2004
Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:4

    Topics: Acculturation; Aged; Aging; California; Cross-Sectional Studies; Depression; Diet; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Sex Factors; Vitamin B 12

2004
Plasma levels of total, free and protein bound thiols as well as sulfane sulfur in different age groups of rats.
    Acta biochimica Polonica, 2004, Volume: 51, Issue:3

    Topics: Aging; Animals; Blood Proteins; Cysteine; Female; Glutathione; Homocysteine; Oxidation-Reduction; Protein Binding; Rats; Rats, Wistar; Sulfhydryl Compounds; Sulfur

2004
Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life.
    Neurobiology of aging, 2005, Volume: 26, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Anxiety; Chi-Square Distribution; Cognition Disorders; Cross-Sectional Studies; Depression; DNA Mutational Analysis; Female; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Personality Inventory; Pteroylpolyglutamic Acids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vitamin B 12

2005
Vascular risk factors and cognitive function in a sample of independently living men.
    Neurobiology of aging, 2005, Volume: 26, Issue:4

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Blood Glucose; Blood Pressure; Body Mass Index; Cardiovascular Physiological Phenomena; Cholesterol; Cognition; Educational Status; Forced Expiratory Flow Rates; Homocysteine; Humans; Male; Memory; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Problem Solving; Psychomotor Performance; Reference Values; Regression Analysis; Risk Factors; Smoking; Task Performance and Analysis; Verbal Learning

2005
Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
    The American journal of medicine, 2005, Volume: 118, Issue:2

    Topics: Aged; Aging; Alzheimer Disease; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Longitudinal Studies; Male; Risk Factors; Vitamin B 12; Vitamin B 6

2005
Life-style habits and homocysteine levels in an elderly population.
    Aging clinical and experimental research, 2004, Volume: 16, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Female; Habits; Homocysteine; Humans; Life Style; Male; Middle Aged; Sex Characteristics

2004
Physiological variation in plasma total homocysteine concentrations in rats.
    Life sciences, 2005, Apr-15, Volume: 76, Issue:22

    Topics: Aging; Animals; Biomarkers; Circadian Rhythm; Disease Models, Animal; Estrous Cycle; Female; Genital Diseases, Female; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar

2005
Low blood pressure is a better predictor of cognitive deficits than the apolipoprotein e4 allele in the oldest old.
    Acta neurologica Scandinavica, 2005, Volume: 111, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Apolipoprotein E4; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Female; Homocysteine; Humans; Hypotension; Male; Mental Status Schedule; Predictive Value of Tests; Prognosis; Sex Factors

2005
Adiponectin levels and cardiovascular risk factors in Japanese men with type 2 diabetes.
    Endocrine journal, 2005, Volume: 52, Issue:2

    Topics: Adiponectin; Adult; Aging; Body Mass Index; Cardiovascular Diseases; Cholesterol, HDL; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Folic Acid; gamma-Glutamyltransferase; Glycated Hemoglobin; Homocysteine; Humans; Intercellular Signaling Peptides and Proteins; Japan; Leukocyte Count; Lipids; Male; Middle Aged; Risk Factors; Smoking

2005
Total homocysteine and its predictors in Dutch children.
    The American journal of clinical nutrition, 2005, Volume: 81, Issue:5

    Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Infant; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Netherlands; Predictive Value of Tests; Vitamin B 12

2005
Age, menopausal status and homocysteine levels in women around menopause.
    European journal of obstetrics, gynecology, and reproductive biology, 2005, Jun-01, Volume: 120, Issue:2

    Topics: Adult; Aging; Cholesterol, HDL; Female; Homocysteine; Humans; Italy; Menopause; Middle Aged; Postmenopause; Premenopause

2005
Purification and characterization of mouse hepatic enzyme that converts selenomethionine to methylselenol by its alpha,gamma-elimination.
    Biological trace element research, 2005, Volume: 106, Issue:1

    Topics: Aging; Ammonium Sulfate; Animals; Brain; Carbon-Sulfur Lyases; Catalysis; Chromatography; Female; Homocysteine; Homoserine; Humans; Intestine, Large; Kinetics; Liver; Male; Methanol; Methionine; Mice; Mice, Inbred ICR; Muscles; Organoselenium Compounds; Selenium; Selenomethionine; Substrate Specificity; Temperature

2005
Population references for plasma total homocysteine concentrations for U.S. children and adolescents in the post-folic acid fortification era.
    The Journal of nutrition, 2005, Volume: 135, Issue:9

    Topics: Adolescent; Aging; Black People; Child; Child, Preschool; Female; Folic Acid; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Male; Mexican Americans; Osmolar Concentration; Reference Values; Sex Factors; White People

2005
Embryonic cerebellar granule cells are resistant to necrosis induced by homocysteine.
    Brain research. Developmental brain research, 2005, Nov-07, Volume: 160, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Cells, Cultured; Disease Susceptibility; Homocysteine; Hyperhomocysteinemia; Mice; Microscopy, Electron, Transmission; Necrosis; Neurodegenerative Diseases; Neurons

2005
Hyperhomocysteinemia and cognitive function: more than just a casual link?
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:3

    Topics: Aging; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors

2005
Homocysteine and folate as risk factors for dementia and Alzheimer disease.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:3

    Topics: Aged; Aging; Alzheimer Disease; Cognition; Cohort Studies; Cross-Sectional Studies; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Italy; Male; Prospective Studies; Risk Factors; Seroepidemiologic Studies

2005
High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Diet; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2005
Elevated levels of plasma homocysteine in postmenopausal women in Burkina Faso.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Chemical Analysis; Burkina Faso; Coronary Disease; Female; Homocysteine; Humans; Menopause; Middle Aged; Sulfhydryl Compounds

2005
Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Cross-Sectional Studies; Dementia; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Neuropsychological Tests; Prospective Studies; Risk Factors; Vitamin B 12

2005
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.
    Neurology, 2005, Nov-08, Volume: 65, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12

2005
Low folate status is associated with impaired cognitive function and dementia in the Sacramento Area Latino Study on Aging.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; California; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Dementia; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Regression Analysis; Vitamin B Complex

2005
Methionine kinetics are altered in the elderly both in the basal state and after vaccination.
    The American journal of clinical nutrition, 2006, Volume: 83, Issue:2

    Topics: Adult; Aged; Aging; Carbon Isotopes; Cysteine; Deuterium; Female; Homocysteine; Humans; Inflammation; Isotope Labeling; Male; Mathematics; Methionine; Methylation; Nutritional Requirements; Postprandial Period; Vaccination

2006
Cardiovascular risk factors in hemodialysis and peritoneal dialysis patients.
    Scandinavian journal of clinical and laboratory investigation, 2005, Volume: 65, Issue:8

    Topics: Adult; Aging; Apolipoproteins A; Apolipoproteins B; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Female; Homocysteine; Humans; Hypertension; Kidney Diseases; Lipoprotein(a); Male; Peritoneal Dialysis; Renal Dialysis; Risk Factors

2005
C-reactive protein and homocysteine are associated with dietary and behavioral risk factors for age-related macular degeneration.
    Nutrition (Burbank, Los Angeles County, Calif.), 2006, Volume: 22, Issue:4

    Topics: Aging; Antioxidants; Biomarkers; C-Reactive Protein; Homocysteine; Humans; Macular Degeneration; Risk Factors; Smoking; Vitamins

2006
Total serum homocysteine, folate and vitamin B12 in a Greek school age population.
    Clinical nutrition (Edinburgh, Scotland), 2006, Volume: 25, Issue:5

    Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Age Factors; Aging; Blood Pressure; Cardiovascular Diseases; Child; Child Nutritional Physiological Phenomena; Female; Folic Acid; Greece; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Reference Values; Risk Factors; Sex Factors; Social Class; Vitamin B 12; Vitamin B Complex

2006
Effect of L-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging.
    Biochemical and biophysical research communications, 2006, Jul-07, Volume: 345, Issue:3

    Topics: Aging; Arginine; Cells, Cultured; Cellular Senescence; Endothelial Cells; Endothelium, Vascular; Homocysteine; Humans; NG-Nitroarginine Methyl Ester; Oxidative Stress; Telomerase; Time Factors

2006
Evaluation of clinical markers of atherosclerosis in young and elderly Japanese adults.
    Clinical chemistry and laboratory medicine, 2006, Volume: 44, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aging; Asian People; Atherosclerosis; Biomarkers; C-Reactive Protein; Female; Homocysteine; Humans; Male; Middle Aged; Sex Characteristics

2006
Relation between vascular risk factors and cognition at age 75.
    Acta neurologica Scandinavica, 2006, Volume: 114, Issue:2

    Topics: Aged; Aging; Alzheimer Disease; Austria; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Cognition Disorders; Cohort Studies; Comorbidity; Cross-Sectional Studies; Female; Glycated Hemoglobin; Homocysteine; Humans; Hyperlipidemias; Hypertension; Lipoproteins; Male; Neuropsychological Tests; Risk Factors; Smoking; Statistics as Topic; Triglycerides

2006
Homocysteine induces DNA damage and alterations in proliferative capacity of T-lymphocytes: a model for immunosenescence?
    Biogerontology, 2007, Volume: 8, Issue:2

    Topics: Aging; Apoptosis; Cell Cycle; Cell Proliferation; Cells, Cultured; Cellular Senescence; Comet Assay; Concanavalin A; DNA Damage; DNA Fragmentation; Dose-Response Relationship, Drug; Homocysteine; Humans; Lymphocyte Activation; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitogens; T-Lymphocytes

2007
Nutritional status is altered in the self-neglecting elderly.
    The Journal of nutrition, 2006, Volume: 136, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Bone and Bones; C-Reactive Protein; Calcifediol; Elder Abuse; Erythrocytes; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Iron; Male; Nutritional Status; Osteocalcin; Self Care; Sex Characteristics; Vitamin D; Vitamins

2006
Reference range of total serum homocysteine level and dietary indexes in healthy Greek schoolchildren aged 6-15 years.
    The British journal of nutrition, 2006, Volume: 96, Issue:4

    Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Aging; Anthropometry; Blood Pressure; Body Mass Index; Child; Child Nutritional Physiological Phenomena; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Sex Characteristics; Vitamin B 12

2006
Total homocysteine, folate, and cobalamin, and their relation to genetic polymorphisms, lifestyle and body mass index in healthy children and adolescents.
    Pediatric research, 2006, Volume: 60, Issue:6

    Topics: Adolescent; Aging; Blood Pressure; Body Mass Index; Child; Child, Preschool; Cholesterol; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Sex Characteristics; Triglycerides; Vitamin B 12

2006
Population reference values for plasma total homocysteine concentrations in US adults after the fortification of cereals with folic acid.
    The American journal of clinical nutrition, 2006, Volume: 84, Issue:5

    Topics: Adult; Age Distribution; Aged; Aging; Edible Grain; Female; Folic Acid; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Male; Mexican Americans; Middle Aged; Nutrition Surveys; Reference Values; Sex Distribution; White People

2006
Differences in expression of cardiovascular risk factors among type 2 diabetes mellitus patients of different age.
    Annals of the New York Academy of Sciences, 2006, Volume: 1084

    Topics: Adolescent; Adult; Aging; Biomarkers; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Homocysteine; Humans; Male; Reference Values; Risk Factors; Triglycerides

2006
Apolipoprotein E e4 allele affects risk of hyperhomocysteinemia in the elderly.
    The American journal of clinical nutrition, 2006, Volume: 84, Issue:6

    Topics: Aged; Aging; Alleles; Apolipoprotein E4; C-Reactive Protein; Cohort Studies; Confidence Intervals; Dementia; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, VLDL; Male; Odds Ratio; Prospective Studies; Risk Factors; Vascular Diseases

2006
Homocysteine, folate, and vitamin B-12 and cognitive performance in older Chinese adults: findings from the Singapore Longitudinal Ageing Study.
    The American journal of clinical nutrition, 2006, Volume: 84, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; China; Cognition; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Middle Aged; Psychological Tests; Singapore; Vitamin B 12; Vitamin B Complex

2006
Biomarkers of folate and vitamin B12 are related in blood and cerebrospinal fluid.
    Clinical chemistry, 2007, Volume: 53, Issue:2

    Topics: Adult; Aged; Aging; Biomarkers; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12

2007
Summaries for patients. The effect of folic acid on hearing in older adults.
    Annals of internal medicine, 2007, Jan-02, Volume: 146, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Auditory Threshold; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Hearing Loss, Sensorineural; Homocysteine; Humans; Male; Middle Aged

2007
Pathomolecular effects of homocysteine on the aging process: a new theory of aging.
    Medical hypotheses, 2007, Volume: 69, Issue:1

    Topics: Aging; Animals; Homocysteine; Humans; Models, Biological

2007
Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; California; Cognition Disorders; Dementia; Disease Susceptibility; Female; Folic Acid; Health Surveys; Hispanic or Latino; Homocysteine; Humans; Incidence; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12

2007
Associations between folate, vitamin B12, homocysteine and pathologies related to aging: the need to consider complex nutrient-nutrient and gene-nutrient interactions and the functional and socio-economic determinants in population-based studies.
    Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:2

    Topics: Aging; Epidemiology; Folic Acid; Food; Genes; Homocysteine; Humans; Socioeconomic Factors; Vitamin B 12

2007
Association of vitamin B12, folate and homocysteine with functional and pathological characteristics of the elderly in a mountainous village in Sicily.
    Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Diabetes Mellitus; Folic Acid; Homocysteine; Humans; Middle Aged; Neoplasms; Peripheral Vascular Diseases; Sicily; Stroke; Vitamin B 12

2007
Association of thyroid dysfunction with vitamin B12, folate and plasma homocysteine levels in the elderly: a population-based study in Sicily.
    Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Epidemiology; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Sicily; Thyroid Diseases; Vitamin B 12

2007
Elevated plasma homocysteine in older shift-workers: a potential risk factor for cardiovascular morbidity.
    Chronobiology international, 2007, Volume: 24, Issue:1

    Topics: Adult; Aging; C-Reactive Protein; Cardiovascular Diseases; Demography; Employment; Homocysteine; Humans; Israel; Male; Middle Aged; Morbidity; Regression Analysis; Risk Factors; Sleep Disorders, Circadian Rhythm

2007
Homocysteine increases the risk of mortality in elderly individuals.
    The British journal of nutrition, 2007, Volume: 97, Issue:6

    Topics: Aged; Aging; Biomarkers; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Mortality; Selenium; Spain; Survival Analysis; Vitamin B 12

2007
Plasma homocysteine is elevated in elderly patients with memory complaints and vascular disease.
    Dementia and geriatric cognitive disorders, 2007, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Brain; Cognition Disorders; Female; Homocysteine; Humans; Male; Memory Disorders; Middle Aged; Reference Values; Vascular Diseases

2007
Inflammation and hemostasis biomarkers and cardiovascular risk in the elderly: the Cardiovascular Health Study.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:6

    Topics: Aged; Aging; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Cohort Studies; Factor VIII; Female; Fibrinogen; Hemostasis; Homocysteine; Humans; Inflammation Mediators; Interleukin-6; Leukocyte Count; Lipoprotein(a); Male; Prospective Studies; Risk Factors

2007
Relationship of homocysteine levels to quadriceps strength, gait speed, and late-life disability in older adults.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2007, Volume: 62, Issue:4

    Topics: Activities of Daily Living; Aged; Aging; Disability Evaluation; Disabled Persons; Female; Gait; Homocysteine; Humans; Male; Middle Aged; Muscle Strength; Nutrition Surveys; Quadriceps Muscle; Surveys and Questionnaires; Time Factors

2007
Age-associated perturbations in glutathione synthesis in mouse liver.
    The Biochemical journal, 2007, Aug-01, Volume: 405, Issue:3

    Topics: Aging; Amino Acid Sequence; Animals; Cysteine; Dipeptides; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Homocysteine; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phylogeny

2007
Prolonged stress will induce Alzheimer's disease in elderly people by increased release of homocysteic acid.
    Medical hypotheses, 2007, Volume: 69, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Homocysteine; Humans; Mice; Models, Neurological; Rats; Stress, Psychological

2007
Elevated plasma homocysteine concentration in elderly patients with mental illness is mainly related to the presence of vascular disease and not the diagnosis.
    Dementia and geriatric cognitive disorders, 2007, Volume: 24, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Creatinine; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Kidney Function Tests; Male; Mental Disorders; Psychiatric Status Rating Scales; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency

2007
B-vitamins and homocysteine in Spanish institutionalized elderly.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2007, Volume: 77, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Institutionalization; Male; Middle Aged; Regression Analysis; Sex Characteristics; Spain; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency

2007
Changes in mitochondrial DNA deletion, content, and biogenesis in folate-deficient tissues of young rats depend on mitochondrial folate and oxidative DNA injuries.
    The Journal of nutrition, 2007, Volume: 137, Issue:9

    Topics: Aging; Animals; DNA Damage; DNA, Mitochondrial; Folic Acid; Gene Deletion; Homocysteine; Mitochondria; Oxidation-Reduction; Rats; Rats, Wistar; RNA, Messenger

2007
Plasma folate concentration and cognitive performance: Rotterdam Scan Study.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Brain; Cognition; Confidence Intervals; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Memory; Middle Aged; Multivariate Analysis; Netherlands; Odds Ratio; Prospective Studies; Psychomotor Performance

2007
Helicobacter pylori may be involved in cognitive impairment and dementia development through induction of atrophic gastritis, vitamin B-12 folate deficiency, and hyperhomocysteinemia sequence.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Dementia; Folic Acid Deficiency; Gastritis, Atrophic; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency

2007
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women.
    Clinica chimica acta; international journal of clinical chemistry, 2008, Volume: 388, Issue:1-2

    Topics: Adult; Aging; Alleles; Anemia, Iron-Deficiency; Avitaminosis; Brazil; Female; Genotype; Homocysteine; Humans; Methylmalonic Acid; Nutritional Physiological Phenomena; Polymorphism, Genetic; Reproduction; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamins

2008
Concurrent folate treatment prevents Na+,K+-ATPase activity inhibition and memory impairments caused by chronic hyperhomocysteinemia during rat development.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2007, Volume: 25, Issue:8

    Topics: Aging; Animals; Chronic Disease; Cognition; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Motor Activity; Nerve Tissue Proteins; Parietal Lobe; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Space Perception; Synaptic Membranes; Thiobarbituric Acid Reactive Substances; Vitamins

2007
Growth-related changes of parameters of the methylation cycle and jejunal aminopeptidase M in the rat.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 59, Issue:5

    Topics: Aging; Animals; CD13 Antigens; Female; Folic Acid; Growth; Homocysteine; Jejunum; Methylation; Rats; Rats, Inbred Lew; Vitamin B 12

2008
Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese.
    Asia Pacific journal of clinical nutrition, 2007, Volume: 16, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arteriosclerosis; Blood Pressure; Cardiovascular Diseases; Carotid Arteries; Chromatography, High Pressure Liquid; Creatinine; Female; Homocysteine; Humans; Japan; Male; Middle Aged; Risk Factors; Sex Factors; Tunica Intima; Tunica Media; Ultrasonography

2007
Effects of a B-vitamin-deficient diet on exploratory activity, motor coordination, and spatial learning in young adult Balb/c mice.
    Brain research, 2008, Jan-10, Volume: 1188

    Topics: Age Factors; Aging; Animals; Body Weight; Brain; Disease Models, Animal; Drinking; Eating; Exploratory Behavior; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Hyperkinesis; Learning Disabilities; Male; Memory Disorders; Mice; Motor Skills Disorders; Movement; Movement Disorders; Space Perception; Vitamin B 12 Deficiency; Vitamin B Deficiency

2008
Methylmalonic acid values in healthy Dutch children.
    European journal of nutrition, 2008, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aging; Biomarkers; Child; Child, Preschool; Creatinine; Cross-Sectional Studies; Female; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylmalonic Acid; Netherlands; Reference Values; Regression Analysis; Vitamin B 12; Vitamin B 12 Deficiency

2008
Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease.
    Neurobiology of aging, 2009, Volume: 30, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Apolipoprotein E4; China; Female; Folic Acid; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk Factors; Sex Factors

2009
The regional concentrations of S-adenosyl-L-methionine, S-adenosyl-L-homocysteine, and adenosine in rat brain.
    Journal of neurochemistry, 1982, Volume: 38, Issue:3

    Topics: Adenosine; Aging; Animals; Brain; Brain Chemistry; Homocysteine; Male; Pineal Gland; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tissue Distribution

1982
[Homocysteinemia as a risk factor for myocardial infarct--the importance of age and of the homocysteinemia levels].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1995, Volume: 14, Issue:10

    Topics: Adult; Aging; Case-Control Studies; Confidence Intervals; Coronary Disease; Female; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Risk Factors

1995
Effects of ageing on folate metabolism in rats fed a long-term folate deficient diet.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1994, Volume: 64, Issue:4

    Topics: Aging; Animals; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine

1994
Prevalence of cobalamin deficiency in the Framingham elderly population.
    The American journal of clinical nutrition, 1994, Volume: 60, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Cohort Studies; Female; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Intrinsic Factor; Male; Massachusetts; Methylmalonic Acid; Middle Aged; Prevalence; Radioimmunoassay; Reference Values; Surveys and Questionnaires; Vitamin B 12 Deficiency

1994
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population.
    JAMA, 1993, Dec-08, Volume: 270, Issue:22

    Topics: Aged; Aged, 80 and over; Aging; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B Complex

1993
Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study.
    The American journal of clinical nutrition, 1996, Volume: 63, Issue:3

    Topics: Aged; Aging; Cognition; Homocysteine; Humans; Male; Memory; Middle Aged; Pyridoxine; Reference Values; Space Perception; Vitamin B 12

1996
Age- and gender-specific reference intervals for total homocysteine and methylmalonic acid in plasma before and after vitamin supplementation.
    Clinical chemistry, 1996, Volume: 42, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Reference Values; Sex Characteristics; Vitamin B 12; Vitamins

1996
Are different reference intervals for methylmalonic acid and total homocysteine necessary in elderly people?
    European journal of haematology, 1996, Volume: 57, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Reference Values; Vitamin B 12

1996
Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations.
    Circulation, 1996, Dec-01, Volume: 94, Issue:11

    Topics: Aged; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Odds Ratio; Osmolar Concentration; Peritoneal Dialysis, Continuous Ambulatory; Pyridoxine; Renal Dialysis; Risk Factors; Sex Distribution; Vitamin B 12

1996
Hormone replacement therapy and cobalamin status in elderly women.
    The American journal of clinical nutrition, 1996, Volume: 64, Issue:6

    Topics: Aged; Aging; Cohort Studies; Estrogen Replacement Therapy; Female; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12

1996
Glycogen phosphorylase activity in the cerebral cortex of rats during development: effect of homocysteine-induced seizures.
    Brain research, 1995, Oct-02, Volume: 694, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Cerebral Cortex; Cyclic AMP; Homocysteine; Injections; Male; Phosphorylases; Rats; Reference Values; Seizures

1995
Short-term and long-term variability of plasma homocysteine measurement.
    Clinical chemistry, 1997, Volume: 43, Issue:1

    Topics: Adult; Aged; Aging; Analysis of Variance; Female; Homocysteine; Humans; Male; Middle Aged; Reference Values; Sex Characteristics

1997
Is metabolic evidence for vitamin B-12 and folate deficiency more frequent in elderly patients with Alzheimer's disease?
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1997, Volume: 52, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Female; Folic Acid Deficiency; Homocysteine; Hospitalization; Humans; Male; Methylmalonic Acid; Reference Values; Vitamin B 12 Deficiency

1997
Specific [3H]glutamate binding in the cerebral cortex and hippocampus of rats during development: effect of homocysteine-induced seizures.
    Neurochemical research, 1997, Volume: 22, Issue:5

    Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Binding Sites; Cerebral Cortex; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Reference Values; Seizures; Synaptic Membranes; Tritium

1997
Plasma total homocysteine, B vitamins, and risk of coronary atherosclerosis.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:5

    Topics: Adult; Aging; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxal Phosphate; Risk Factors; Sex Characteristics; Vitamin B 12; Vitamin B Complex

1997
Major lifestyle determinants of plasma total homocysteine distribution: the Hordaland Homocysteine Study.
    The American journal of clinical nutrition, 1998, Volume: 67, Issue:2

    Topics: Adult; Aged; Aging; Coffee; Cohort Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Life Style; Male; Reference Values; Sex Factors; Smoking; Surveys and Questionnaires

1998
Plasma total-homocysteine in anorexia nervosa.
    European journal of clinical nutrition, 1998, Volume: 52, Issue:3

    Topics: Adolescent; Aging; Anorexia Nervosa; Child; Chromatography, High Pressure Liquid; Creatinine; Female; Folic Acid; Homocysteine; Humans; Reference Values; Vitamin B 12

1998
Variability and determinants of total homocysteine concentrations in plasma in an elderly population.
    Clinical chemistry, 1998, Volume: 44, Issue:1

    Topics: Aged; Aging; Blood Pressure; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Male; Regression Analysis; Reproducibility of Results; Seasons; Sex Factors; Vitamin B 12

1998
The increase of plasma homocysteine concentrations with age is partly due to the deterioration of renal function as determined by plasma cystatin C.
    Clinical chemistry and laboratory medicine, 1998, Volume: 36, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Creatinine; Cystatin C; Cystatins; Female; Glomerular Filtration Rate; Homocysteine; Humans; Kidney; Male; Middle Aged; Sex Factors; Sweden

1998
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.
    Archives of neurology, 1998, Volume: 55, Issue:11

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Memory Disorders; Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Risk Factors; Vascular Diseases; Vitamin B 12

1998
Plasma total homocysteine and cysteine in relation to glomerular filtration rate in diabetes mellitus.
    Kidney international, 1999, Volume: 55, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Creatinine; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Insulin; Middle Aged; Vitamin B 12

1999
Plasma homocysteine concentrations of preterm infants.
    Biology of the neonate, 1999, Volume: 76, Issue:2

    Topics: Adult; Aging; Cysteine; Female; Gestational Age; Homocysteine; Humans; Infant, Newborn; Infant, Premature; Male; Reference Values

1999
Serum folate and homocysteine concentrations in large population samples of US ethnic and racial groups.
    The American journal of clinical nutrition, 1999, Volume: 70, Issue:5

    Topics: Adolescent; Aging; Child; Female; Folic Acid; Homocysteine; Humans; Male; Mexican Americans; Racial Groups; United States; White People

1999
Methylenetetrahydrofolate reductase polymorphism, plasma homocysteine and age.
    European journal of clinical investigation, 1999, Volume: 29, Issue:12

    Topics: Adult; Aged; Aging; Arteriosclerosis; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic

1999
Effects of methionine-induced hyperhomocysteinemia on endothelium-dependent vasodilation and oxidative status in healthy adults.
    Circulation, 2000, Feb-08, Volume: 101, Issue:5

    Topics: Adult; Aged; Aging; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Oxidation-Reduction; Prospective Studies; Vasodilation

2000
Community-living nonagenarians in northern ireland have lower plasma homocysteine but similar methylenetetrahydrofolate reductase thermolabile genotype prevalence compared to 70-89-year-old subjects.
    Atherosclerosis, 2000, Volume: 149, Issue:1

    Topics: Age Distribution; Aged; Aged, 80 and over; Aging; Chromatography, Liquid; Cross-Sectional Studies; Female; Gene Expression; Genotype; Glomerular Filtration Rate; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Northern Ireland; Oxidoreductases Acting on CH-NH Group Donors; Population Surveillance; Prevalence; Vitamin B Complex

2000
Homocysteine and other thiol compounds in ageing.
    BioFactors (Oxford, England), 2000, Volume: 11, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Cysteine; Female; Glutathione; Homocysteine; Humans; Male; Sulfhydryl Compounds

2000
Using homocysteine and related metabolites to diagnose vitamin deficiency states.
    BioFactors (Oxford, England), 2000, Volume: 11, Issue:1-2

    Topics: Aging; Animals; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency

2000
Plasma total homocysteine and cognitive performance in a volunteer elderly population.
    Annals of the New York Academy of Sciences, 2000, Volume: 903

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Female; Homocysteine; Humans; Longitudinal Studies; Male; Mental Status Schedule; Middle Aged; Reference Values; Regression Analysis

2000
Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey.
    American journal of epidemiology, 2000, Jul-15, Volume: 152, Issue:2

    Topics: Adolescent; Adult; Aged; Aging; Contraceptives, Oral, Hormonal; Creatinine; Estrogens; Female; Folic Acid; Health Surveys; Homocysteine; Hormone Replacement Therapy; Humans; Male; Middle Aged; United States; Vitamin B 12

2000
Changes in the intracellular homocysteine and glutathione content associated with aging.
    Life sciences, 2000, Aug-04, Volume: 67, Issue:11

    Topics: Aged; Aged, 80 and over; Aging; Female; Glutathione; Homocysteine; Humans; Male; Thiobarbituric Acid Reactive Substances; Vitamin E

2000
Increased homocyst(e)ine associated with smoking, chronic inflammation, and aging may reflect acute-phase induction of pyridoxal phosphatase activity.
    Medical hypotheses, 2000, Volume: 55, Issue:4

    Topics: Acute-Phase Reaction; Aged; Aging; Chronic Disease; Coffee; Enzyme Induction; Homocysteine; Homocystine; Humans; Inflammation; Interleukin-6; Liver; Models, Biological; Phosphoric Monoester Hydrolases; Pyridoxine; Smoking

2000
Age-related hearing impairment and B vitamin status.
    Acta oto-laryngologica, 2000, Volume: 120, Issue:5

    Topics: Acoustic Impedance Tests; Age Factors; Aged; Aged, 80 and over; Aging; Audiometry, Pure-Tone; Audiometry, Speech; Female; Folic Acid; Homocysteine; Humans; Male; Presbycusis; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency

2000
Plasma total homocysteine and retinal vascular disease.
    Eye (London, England), 2000, Volume: 14 ( Pt 4)

    Topics: Adult; Age Factors; Aged; Aging; Biomarkers; Creatinine; Female; Homocysteine; Humans; Male; Middle Aged; Retinal Artery Occlusion; Retinal Vein Occlusion; Risk Factors

2000
Folate intake, lifestyle factors, and homocysteine concentrations in younger and older women.
    The American journal of clinical nutrition, 2000, Volume: 72, Issue:5

    Topics: Adult; Aged; Aging; Blood Pressure; Body Mass Index; Coffee; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Life Style; Linear Models; Middle Aged; Reference Values; Smoking

2000
Blood homocysteine and vitamin B levels are not associated with cognitive skills in healthy normally ageing subjects.
    The journal of nutrition, health & aging, 2000, Volume: 4, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cognition; Dementia; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B 12

2000
Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:2

    Topics: Aged; Aging; Asian People; Cohort Studies; Exercise; Female; Folic Acid; Genotype; Homocysteine; Humans; Interviews as Topic; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Prospective Studies; Pyridoxine; Risk Factors; Sex Factors; Singapore; Smoking; Vascular Diseases; Vitamin B 12

2001
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment.
    Mechanisms of ageing and development, 2000, Dec-20, Volume: 121, Issue:1-3

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Dementia; Dementia, Vascular; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Male; Pyridoxine; Reference Values; Vitamin B 12

2000
Cellular resistance to homocysteine: a key for longevity.
    Atherosclerosis, 2000, Volume: 152, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Blood Platelets; Female; Homocysteine; Humans; Longevity; Male; Middle Aged; Nitric Oxide

2000
Lifestyle effects on homocysteine and an alcohol paradox.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:3

    Topics: Aged; Aging; Alcohol Drinking; Animals; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male

2001
Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Cross-Sectional Studies; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Life Style; Linear Models; Male; Methylmalonic Acid; Risk Factors; Smoking; Tea; Vascular Diseases; Vitamin B 12

2001
The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study.
    Atherosclerosis, 2001, Feb-15, Volume: 154, Issue:3

    Topics: Aged; Aging; Alleles; Demography; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Regression Analysis; Sex Characteristics; Vitamin B 12

2001
Simultaneous determination of total plasma glutathione, homocysteine, cysteinylglycine, and methionine by high-performance liquid chromatography with electrochemical detection.
    Journal of clinical laboratory analysis, 2001, Volume: 15, Issue:3

    Topics: Aging; Calibration; Chromatography, High Pressure Liquid; Diabetes Mellitus; Dipeptides; Female; Glutathione; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methionine; Quality Control; Reference Values; Risk Factors; Sensitivity and Specificity

2001
Plasma homocysteine, methylenetetrahydrofolate reductase mutation and carotid damage in elderly healthy women.
    Atherosclerosis, 2001, Volume: 157, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Carotid Arteries; Female; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors

2001
High plasma homocyst(e)ine levels in elderly Japanese patients are associated with increased cardiovascular disease risk independently from markers of coagulation activation and endothelial cell damage.
    Atherosclerosis, 2001, Volume: 157, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Asian People; Biomarkers; Blood Coagulation; Cardiovascular Diseases; Endothelium, Vascular; Factor VIIa; Female; Homocysteine; Humans; Japan; Male; Middle Aged; Peptide Fragments; Prothrombin; Risk Factors

2001
Hyperhomocysteinemia in advanced age.
    Clinical chemistry and laboratory medicine, 2001, Volume: 39, Issue:8

    Topics: Aged; Aging; Chronic Disease; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Time Factors; Vitamin B 6

2001
Transcobalamin polymorphism and homocysteine.
    Blood, 2001, Dec-01, Volume: 98, Issue:12

    Topics: Aged; Aging; Dementia; Female; Genotype; Homocysteine; Humans; Male; Polymorphism, Genetic; Transcobalamins

2001
Hyperhomocysteinemia and related factors in 600 hospitalized elderly subjects.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Dementia; Diabetes Complications; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Kinetics; Linear Models; Male; Methionine; Nutrition Disorders; Odds Ratio; Renal Insufficiency; Vascular Diseases

2001
Homocysteine levels in elderly Spanish people: influence of pyridoxine, vitamin B12 and folic acid intakes.
    The journal of nutrition, health & aging, 2002, Volume: 6, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; Diet Records; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Male; Prospective Studies; Pyridoxine; Spain; Vitamin B 12

2002
Short-term folic acid supplementation induces variable and paradoxical changes in plasma homocyst(e)ine concentrations.
    Lipids, 2001, Volume: 36 Suppl

    Topics: Aged; Aging; Cystathionine beta-Synthase; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Sex Characteristics; Smoking; Vitamins

2001
The Hordaland Homocysteine Studies.
    Lipids, 2001, Volume: 36 Suppl

    Topics: Adult; Aged; Aging; Blood Pressure; Cardiovascular Diseases; Cholesterol; Coffee; Cohort Studies; Diet; Exercise; Female; Homocysteine; Humans; Life Style; Male; Middle Aged; Norway; Pregnancy; Pregnancy Outcome; Risk Factors; Sex Characteristics; Surveys and Questionnaires; Vitamins

2001
Homocysteine and life-style in the elderly.
    Aging (Milan, Italy), 2001, Volume: 13, Issue:6

    Topics: Aged; Aging; Blood Pressure; Creatinine; Female; Geriatric Assessment; Homocysteine; Humans; Life Style; Male; Nutritional Status; Sex Factors; Smoking

2001
Micro- and macrovascular complications and hyperhomocysteinaemia in type 1 diabetic patients.
    Diabetes & metabolism, 2001, Volume: 27, Issue:6

    Topics: Adult; Aging; Blood Pressure; Cholesterol; Cholesterol, HDL; Creatinine; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Retinopathy; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Time Factors

2001
Correlates of plasma homocysteine, cysteine and cysteinyl-glycine in respondents in the British National Diet and Nutrition Survey of young people aged 4-18 years, and a comparison with the survey of people aged 65 years and over.
    The British journal of nutrition, 2002, Volume: 87, Issue:1

    Topics: Adolescent; Aged; Aging; Biomarkers; Child; Child, Preschool; Cysteine; Diet Surveys; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Seasons; Sex Factors; Smoking; United Kingdom; Vitamin B 12; Vitamin B 6

2002
Homocysteine, B vitamin status, and cognitive function in the elderly.
    The American journal of clinical nutrition, 2002, Volume: 75, Issue:5

    Topics: Aged; Aging; Cognition; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Intelligence; Male; Psychological Tests; Vitamin B 12

2002
Relationship between plasma homocysteine levels and brain atrophy in healthy elderly individuals.
    Neurology, 2002, May-28, Volume: 58, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Atrophy; Brain; Female; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged

2002
Low vitamin B-12 intake and status are more prevalent in Hispanic older adults of Caribbean origin than in neighborhood-matched non-Hispanic whites.
    The Journal of nutrition, 2002, Volume: 132, Issue:7

    Topics: Aged; Aged, 80 and over; Aging; Diet; Dominican Republic; Hispanic or Latino; Homocysteine; Humans; Middle Aged; Prevalence; Puerto Rico; Vitamin B 12; Vitamin B 12 Deficiency; White People

2002
Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions.
    Canadian journal of biochemistry, 1979, Volume: 57, Issue:1

    Topics: Aging; Animals; Female; Homocysteine; Liver; Methylation; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine

1979
Age dependency of cystathionine beta-synthase activity in human fibroblasts in homocyst(e)inemia and atherosclerotic vascular disease.
    Atherosclerosis, 1992, Volume: 94, Issue:2-3

    Topics: Adult; Aged; Aging; Arteriosclerosis; Cells, Cultured; Cystathionine beta-Synthase; Down Syndrome; Female; Fibroblasts; Homocysteine; Homocystinuria; Humans; Male; Middle Aged; Skin

1992
Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status.
    European journal of clinical investigation, 1992, Volume: 22, Issue:2

    Topics: Adult; Aged; Aging; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Pyridoxal Phosphate; Sex Characteristics; Vascular Diseases; Vitamin B 12

1992
S-adenosylmethionine, S-adenosylhomocysteine and adenosine system. Age-dependent availability in rat brain.
    Developmental pharmacology and therapeutics, 1989, Volume: 13, Issue:2-4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Brain; Homocysteine; In Vitro Techniques; Kinetics; Male; Membranes; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine

1989
Folic acid responsive postmenopausal homocysteinemia.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:11

    Topics: Adult; Aging; Cystine; Dipeptides; Fasting; Female; Folic Acid; Glycine; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Serine

1985
Methylation of myelin basic protein by enzymes from rat brain.
    Journal of neurochemistry, 1974, Volume: 23, Issue:6

    Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration

1974
Convulsions induced in 10-day-old rats by intraperitional injection of monosodium glutamate and related excitant amino acids.
    Biochemical pharmacology, 1973, Jan-01, Volume: 22, Issue:1

    Topics: Aging; Amino Acids; Amino Acids, Diamino; Animals; Food Additives; Glutamates; Homocysteine; Neurons; Oxalates; Propionates; Rats; Seizures; Time Factors; Toxins, Biological

1973
Methionine metabolism in mammals. Regulation of homocysteine methyltransferases in rat tissue.
    Archives of biochemistry and biophysics, 1971, Volume: 146, Issue:1

    Topics: Aging; Alloxan; Animals; Betaine; Chromatography, Gel; Cycloheximide; Cysteine; Dactinomycin; Dietary Proteins; Enzyme Induction; Enzyme Repression; Glucagon; Homocysteine; Hormones; Liver; Male; Methionine; Methyltransferases; Organ Specificity; Rats; Tetrahydrofolates; Ultracentrifugation

1971