homocysteine and Age-Related Memory Disorders

homocysteine has been researched along with Age-Related Memory Disorders in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.13)18.2507
2000's11 (34.38)29.6817
2010's19 (59.38)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Dos Santos, TM; Kolling, J; Netto, CA; Sanches, EF; Siebert, C; Wyse, ATS1
Barrero, C; Li, JG; Merali, S; Praticò, D1
Jadavji, NM; Pjetri, E; Prieur, EAK; Zeisel, SH1
Cole, PD; Gulinello, ME; Maxwell, RR; Spira, M; Wen, J; Wolf, AJ1
Huang, F; Ke, D; Liu, R; Mahaman, YAR; Salissou, MTM; Wang, JZ; Wang, Q; Wang, X; Wang, Y; Xu, Z; Zhang, B; Zhu, F1
Chen, J; He, ZF; Lu, YQ; Luo, Y; Wang, Y; Yan, BL; Yu, Q1
Chen, R; Hu, J; Liu, R; Liu, X; Tian, Q; Wang, JZ; Wang, P; Wang, Q; Wang, XC; Xia, Y; Zeng, K1
Abdel Baki, SG; Bergold, PJ; Berrocal-Zaragoza, MI; Fernandez-Ballart, JD; Murphy, MM; Quadros, EV; Sequeira, JM1
Ji, ZH; Liu, C; Yu, XY; Zhao, H1
Caudill, MA; Deng, L; Jadavji, NM; Malysheva, O; Rozen, R1
Hiramatsu, M; Kinoshita, S; Kunisawa, K; Nagao, M; Nakashima, N; Nomura, T1
Chen, Y; Hong, Y; Wang, W; Xiao, Z; Yu, L1
Cunha, AA; Dos Santos, TM; Mackedanz, V; Matté, C; Netto, CA; Pereira, LO; Wyse, AT1
Cunningham, M; DeBoynton, VL; Marsh, GM; Martin, RL; Summers, WK1
Cole, PD; Gulinello, M; Li, Y; Vijayanathan, V1
Benetos, A; Boivin, JM; Bracard, S; Fay, R; Felblinger, J; Kearney-Schwartz, A; Lacolley, P; Marteau, JB; Rossignol, P; Visvikis-Siest, S; Watfa, G; Zannad, F1
Ali, N; Cole, PD; Gulinello, M; Vijayanathan, V1
Ellis, KA; Macpherson, H; Pipingas, A; Sali, A1
Humpel, C; Pirchl, M; Sperner-Unterweger, B; Ullrich, C1
Ehrlich, D; Humpel, C1
Chai, GS; Cheng, XS; Jiang, X; Liu, GP; Ma, ZW; Ni, ZF; Wang, JZ; Wang, Q; Xie, AJ1
Franzon, R; Lammers, ML; Matté, C; Netto, CA; Reis, EA; Tagliari, B; Wyse, AT; Zugno, AI1
Carmel, R; James, SJ; Melnyk, S1
Miller, AL1
Bleich, S; Bönsch, D; de Zwaan, M; Frieling, H; Gruss, B; Hillemacher, T; Jacoby, GE; Kornhuber, J; Römer, KD; Röschke, B; Wilhelm, J1
Engedal, K; Nurk, E; Nygaard, HA; Refsum, H; Smith, AD; Tell, GS; Ueland, PM; Vollset, SE1
Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M1
Bertoletti, E; Chilovi, BV; Conti, M; Del Rio, I; Padovani, A; Rozzini, L; Trabucchi, M1
Gustafson, L; Hultberg, B; Nilsson, K1
Barschak, AG; Matté, C; Netto, CA; Scherer, EB; Stefanello, FM; Vargas, CR; Wyse, AT1
Barraud, H; Bronowicki, JP; Guéant, JL; Lalonde, R; Ravey, J; Strazielle, C1
Clarke, R; Jobst, KA; Refsum, H; Smith, AD; Sutton, L; Ueland, PM1

Reviews

1 review(s) available for homocysteine and Age-Related Memory Disorders

ArticleYear
The methionine-homocysteine cycle and its effects on cognitive diseases.
    Alternative medicine review : a journal of clinical therapeutic, 2003, Volume: 8, Issue:1

    Topics: Alzheimer Disease; Cardiovascular Diseases; Cognition Disorders; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Memory Disorders; Methionine; Methionine Adenosyltransferase; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6

2003

Trials

2 trial(s) available for homocysteine and Age-Related Memory Disorders

ArticleYear
Complex antioxidant blend improves memory in community-dwelling seniors.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 19, Issue:2

    Topics: Aged; Antioxidants; Drug Therapy, Combination; Female; Geriatric Assessment; Homocysteine; Humans; Male; Memory Disorders; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Residence Characteristics

2010
Memory improvements in elderly women following 16 weeks treatment with a combined multivitamin, mineral and herbal supplement: A randomized controlled trial.
    Psychopharmacology, 2012, Volume: 220, Issue:2

    Topics: Aged; Aged, 80 and over; Biomarkers; Dietary Supplements; Double-Blind Method; Female; Homocysteine; Humans; Inflammation Mediators; Memory Disorders; Middle Aged; Minerals; Oxidative Stress; Phytotherapy; Psychological Tests; Reaction Time; Vitamins

2012

Other Studies

29 other study(ies) available for homocysteine and Age-Related Memory Disorders

ArticleYear
Chronic mild hyperhomocysteinemia induces anxiety-like symptoms, aversive memory deficits and hippocampus atrophy in adult rats: New insights into physiopathological mechanisms.
    Brain research, 2020, 02-01, Volume: 1728

    Topics: Adenosine Triphosphate; Animals; Anxiety; Atrophy; Avoidance Learning; Chronic Disease; DNA Damage; Electron Transport Complex IV; Hippocampus; Homocysteine; Hyperhomocysteinemia; Male; Memory Disorders; Open Field Test; Oxidative Stress; Rats; Rats, Wistar

2020
Genetic absence of ALOX5 protects from homocysteine-induced memory impairment, tau phosphorylation and synaptic pathology.
    Human molecular genetics, 2017, 05-15, Volume: 26, Issue:10

    Topics: Animals; Arachidonate 5-Lipoxygenase; Brain; Disease Models, Animal; Female; Homocysteine; Humans; Male; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurodegenerative Diseases; Phosphorylation; Synapses

2017
Reduced brain volume and impaired memory in betaine homocysteine S-methyltransferase knockout mice.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2017, Volume: 42, Issue:11

    Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Brain; Gene Deletion; Homocysteine; Magnetic Resonance Imaging; Male; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size

2017
Methotrexate causes persistent deficits in memory and executive function in a juvenile animal model.
    Neuropharmacology, 2018, 09-01, Volume: 139

    Topics: Animals; Brain; Cell Proliferation; Cognition Disorders; Executive Function; Female; Folic Acid Antagonists; Homocysteine; Male; Memory Disorders; Methotrexate; Microglia; Pattern Recognition, Visual; Rats, Long-Evans; Recognition, Psychology; Spatial Memory

2018
Methanolic extract of
    Aging, 2018, 11-12, Volume: 10, Issue:11

    Topics: Alzheimer Disease; Animals; Homocysteine; Hyperhomocysteinemia; Male; Memory Disorders; Methanol; Neurons; Oxidative Stress; Phosphorus Compounds; Phosphotransferases; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Tamaricaceae; tau Proteins

2018
Hydroxysafflor yellow A ameliorates homocysteine-induced Alzheimer-like pathologic dysfunction and memory/synaptic disorder.
    Rejuvenation research, 2013, Volume: 16, Issue:6

    Topics: Alzheimer Disease; Animals; Blotting, Western; Chalcone; Enzyme-Linked Immunosorbent Assay; Homocysteine; Male; Maze Learning; Memory Disorders; Quinones; Rats; Rats, Sprague-Dawley; Synapses

2013
Novel multipotent AChEI-CCB attenuates hyperhomocysteinemia-induced memory deficits and Neuropathologies in rats.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 42, Issue:3

    Topics: Animals; Brain Diseases; Calcium Channel Blockers; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Drug Therapy, Combination; Hippocampus; Homocysteine; Hyperhomocysteinemia; Indans; Male; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Nifedipine; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Silver Staining; Tacrine

2014
Folate deficiency in rat pups during weaning causes learning and memory deficits.
    The British journal of nutrition, 2014, Oct-28, Volume: 112, Issue:8

    Topics: Animals; Behavior, Animal; Brain; Cerebellum; Diet; Disease Susceptibility; Female; Folic Acid; Folic Acid Deficiency; Hippocampus; Homocysteine; Lactation; Learning Disabilities; Liver; Male; Maternal Nutritional Physiological Phenomena; Memory Disorders; Memory, Long-Term; Neurons; Rats, Long-Evans; Spatial Learning; Weaning

2014
Neuroprotection and mechanisms of atractylenolide III in preventing learning and memory impairment induced by chronic high-dose homocysteine administration in rats.
    Neuroscience, 2015, Apr-02, Volume: 290

    Topics: Animals; Apoptosis; Caspase 3; Cells, Cultured; Hippocampus; Homocysteine; Lactones; Learning Disabilities; Male; Maze Learning; Memory Disorders; Neurons; Neuroprotective Agents; Protein Kinase C; Random Allocation; Rats, Wistar; Reactive Oxygen Species; Sesquiterpenes; Spatial Memory

2015
MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring.
    Neuroscience, 2015, Aug-06, Volume: 300

    Topics: Animals; Apoptosis; Body Weight; Choline Deficiency; Choline O-Acetyltransferase; Disease Models, Animal; Female; Folic Acid Deficiency; Hippocampus; Homocysteine; Homocystinuria; Male; Maternal Nutritional Physiological Phenomena; Maze Learning; Memory Disorders; Memory, Short-Term; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Transgenic; Muscle Spasticity; Neurogenesis; Organ Size; Pregnancy; Pregnancy Complications; Psychotic Disorders; Recognition, Psychology

2015
Betaine prevents homocysteine-induced memory impairment via matrix metalloproteinase-9 in the frontal cortex.
    Behavioural brain research, 2015, Oct-01, Volume: 292

    Topics: Animals; Betaine; Drug Interactions; Frontal Lobe; Homocysteine; Hyperhomocysteinemia; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; Memory Disorders; Mice

2015
Multi-Vitamin B Supplementation Reverses Hypoxia-Induced Tau Hyperphosphorylation and Improves Memory Function in Adult Mice.
    Journal of Alzheimer's disease : JAD, 2016, 08-04, Volume: 54, Issue:1

    Topics: Animals; Avoidance Learning; Cerebral Cortex; Choline; Dietary Supplements; Disease Models, Animal; Folic Acid; Glycogen Synthase Kinase 3 beta; Hippocampus; Homocysteine; Hypoxia; Male; Maze Learning; Memory; Memory Disorders; Mice; Phosphorylation; tau Proteins; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2016
Acute homocysteine administration impairs memory consolidation on inhibitory avoidance task and decreases hippocampal brain-derived neurotrophic factor immunocontent: prevention by folic acid treatment.
    Neuroscience, 2009, Nov-10, Volume: 163, Issue:4

    Topics: Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Folic Acid; Hippocampus; Homocysteine; Hyperhomocysteinemia; Memory; Memory Disorders; Memory, Short-Term; Motor Activity; Parietal Lobe; Random Allocation; Rats; Rats, Wistar; Time Factors; Vitamin B Complex

2009
Intrathecal methotrexate induces focal cognitive deficits and increases cerebrospinal fluid homocysteine.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 95, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Behavior, Animal; Cisterna Magna; Cognition Disorders; Disease Models, Animal; Folic Acid; Folic Acid Antagonists; Homocysteine; Inflammation Mediators; Injections, Spinal; Male; Memory Disorders; Methotrexate; Motor Activity; Neuropsychological Tests; Psychomotor Performance; Rats; Rats, Long-Evans; Recognition, Psychology; Time Factors

2010
Association study of gene polymorphisms involved in vascular alterations in elderly hypertensives with subjective memory complaints.
    Dementia and geriatric cognitive disorders, 2010, Volume: 30, Issue:5

    Topics: Aged; Aged, 80 and over; Apolipoproteins E; Blood Pressure; Blood Vessels; Cognition Disorders; Cross-Sectional Studies; Data Interpretation, Statistical; Female; Genetic Association Studies; Genetic Variation; Genotype; Homocysteine; Humans; Hypertension; Inflammation; Lipid Metabolism; Magnetic Resonance Imaging; Male; Memory Disorders; Middle Aged; Multigene Family; Polymorphism, Genetic; Thrombosis

2010
Persistent cognitive deficits, induced by intrathecal methotrexate, are associated with elevated CSF concentrations of excitotoxic glutamate analogs and can be reversed by an NMDA antagonist.
    Behavioural brain research, 2011, Dec-01, Volume: 225, Issue:2

    Topics: Animals; Cognition Disorders; Dextromethorphan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Folic Acid; Glutamic Acid; Homocysteine; Humans; Injections, Spinal; Male; Memory Disorders; Methotrexate; Rats; Rats, Long-Evans; Recognition, Psychology

2011
Homocysteine has anti-inflammatory properties in a hypercholesterolemic rat model in vivo.
    Molecular and cellular neurosciences, 2012, Volume: 49, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Disease Models, Animal; Homocysteine; Hypercholesterolemia; Immunohistochemistry; Inflammation; Learning; Male; Memory Disorders; Rats; Rats, Sprague-Dawley

2012
Chronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood-brain barrier leakage in rats in vivo.
    Journal of the neurological sciences, 2012, Nov-15, Volume: 322, Issue:1-2

    Topics: Animals; Blood-Brain Barrier; Cholesterol; Cholinergic Neurons; Dietary Supplements; Disease Models, Animal; Ethanol; Homocysteine; Hypercholesterolemia; Hyperhomocysteinemia; Inflammation; Male; Maze Learning; Memory Disorders; Rats; Rats, Sprague-Dawley; Risk Factors; Space Perception; Time Factors

2012
Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.
    Journal of neurochemistry, 2013, Volume: 124, Issue:3

    Topics: Alzheimer Disease; Animals; Betaine; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Male; Memory Disorders; Rats; Rats, Sprague-Dawley

2013
Pretreatment with vitamins E and C prevent the impairment of memory caused by homocysteine administration in rats.
    Metabolic brain disease, 2002, Volume: 17, Issue:3

    Topics: Animals; Antioxidants; Avoidance Learning; Homocysteine; Male; Memory Disorders; Oxidative Stress; Rats; Rats, Wistar; Vitamin E

2002
Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.
    Blood, 2003, Apr-15, Volume: 101, Issue:8

    Topics: Anemia; Anemia, Pernicious; Cysteine; Dipeptides; Folic Acid; Glutathione; Homocysteine; Humans; Memory Disorders; Methionine; Movement Disorders; Nervous System Diseases; Retrospective Studies; S-Adenosylmethionine; Sensation Disorders; Vitamin B 12; Vitamin B 12 Deficiency

2003
Cognitive impairment and its association with homocysteine plasma levels in females with eating disorders - findings from the HEaD-study.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Anorexia Nervosa; Brain; Brain Chemistry; Bulimia Nervosa; Case-Control Studies; Cognition Disorders; Feeding and Eating Disorders; Female; Homocysteine; Humans; Long-Term Potentiation; Memory; Memory Disorders; Middle Aged; Neuropsychological Tests; Prospective Studies; Receptors, N-Methyl-D-Aspartate; Sex Factors; Synaptic Transmission; Up-Regulation

2005
Plasma total homocysteine and memory in the elderly: the Hordaland Homocysteine Study.
    Annals of neurology, 2005, Volume: 58, Issue:6

    Topics: Aged; Biomarkers; Cross-Sectional Studies; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Memory; Memory Disorders; Prospective Studies; Risk Factors; Vitamin B 12

2005
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.
    Neurology, 2005, Nov-08, Volume: 65, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12

2005
Angiotensin converting enzyme (ACE) inhibitors modulate the rate of progression of amnestic mild cognitive impairment.
    International journal of geriatric psychiatry, 2006, Volume: 21, Issue:6

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Cognition Disorders; Dementia; Disease Progression; Educational Status; Female; Homocysteine; Humans; Male; Memory Disorders; Neuropsychological Tests; Prognosis; Psychiatric Status Rating Scales; Risk Factors

2006
Plasma homocysteine is elevated in elderly patients with memory complaints and vascular disease.
    Dementia and geriatric cognitive disorders, 2007, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Brain; Cognition Disorders; Female; Homocysteine; Humans; Male; Memory Disorders; Middle Aged; Reference Values; Vascular Diseases

2007
Concurrent folate treatment prevents Na+,K+-ATPase activity inhibition and memory impairments caused by chronic hyperhomocysteinemia during rat development.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2007, Volume: 25, Issue:8

    Topics: Aging; Animals; Chronic Disease; Cognition; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Motor Activity; Nerve Tissue Proteins; Parietal Lobe; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Space Perception; Synaptic Membranes; Thiobarbituric Acid Reactive Substances; Vitamins

2007
Effects of a B-vitamin-deficient diet on exploratory activity, motor coordination, and spatial learning in young adult Balb/c mice.
    Brain research, 2008, Jan-10, Volume: 1188

    Topics: Age Factors; Aging; Animals; Body Weight; Brain; Disease Models, Animal; Drinking; Eating; Exploratory Behavior; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Hyperkinesis; Learning Disabilities; Male; Memory Disorders; Mice; Motor Skills Disorders; Movement; Movement Disorders; Space Perception; Vitamin B 12 Deficiency; Vitamin B Deficiency

2008
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.
    Archives of neurology, 1998, Volume: 55, Issue:11

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Memory Disorders; Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Risk Factors; Vascular Diseases; Vitamin B 12

1998
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