homocysteine and Abnormality, Heart

homocysteine has been researched along with Abnormality, Heart in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (7.69)	18.2507
2000's	23 (44.23)	29.6817
2010's	21 (40.38)	24.3611
2020's	4 (7.69)	2.80

Authors

Authors	Studies
Attri, SV; Dash, N; Rohit, MK; Sankhyan, N; Tyagi, R; Verma, S	1
Finnell, RH; Hou, J; Huang, L; Jin, L; Lin, Y; Liu, Z; Ma, J; Mei, X; Nie, J; Qi, D; Saiyin, H; Si, W; Wang, H; Wang, J; Xu, W; Xue, Y; Ye, J; Zhang, T; Zhao, J; Zhao, S; Zhao, Y; Zhu, P	1
Chen, M; Huang, P; Jiang, Z; Lin, N; Shi, H; Sun, X; Wang, L; Yang, S; Yu, R	1
Chu, G; Lai, G; Liang, X; Wang, L; Zhao, Y	1
Baumert, M; Paprotny, M; Surmiak, P	1
Elizabeth, KE; Jissa, VT; Pillai, MR; Praveen, SL; Preethi, NR	1
Bayraktar, N; Gulumser, C; Kocaman, E; Sahin-Uysal, N; Varan, B; Yanık, F	1
Linask, KK	1
Chen, YJ; Duan, WY; Gong, XH; Huang, GY; Jiang, SS; Jin, L; Lu, CQ; Peng, QQ; Qiao, B; Shen, HB; Wang, HY; Zhao, JY	1
Mohammed, D; Rezk, NA; Zidan, HE	1
Gelb, BD	1
Alanay, Y; Alehan, D; Alikasifoglu, M; Sahiner, UM; Tuncbilek, E	1
Kimura, A	1
Cleves, MA; Erickson, SW; Hobbs, CA; Li, J; Li, M; Macleod, SL; Malik, S; Nick, T; Tang, X	1
Li, Y; Pan, W; Sun, L; Sun, S; Wang, S; Xie, Y; Zhang, Z	1
Dong, X; Wei, Y; Wu, X; Yang, R; Yang, Y	1
Jiang, Y; Liu, C; Mei, J; Qian, X; Yang, H; Zhang, S; Zhang, W	1
Dao, J; Li, M; Song, X; Zhu, W	1
He, X; Hong, X; Kang, F; Li, L; Sun, Q; Zeng, F	1
Iovannisci, DM; Kuehl, K; Lammer, EJ; Loffredo, C; Shaw, GM	1
Alves da Silva, AF; Biselli, JM; Carvalho, VM; Eberlin, MN; Goloni-Bertollo, EM; Haddad, R; Machado, FB; Medina-Acosta, E; Pavarino-Bertelli, EC; Vannucchi, H; Zampieri, BL	1
Caudill, MA; Chan, J; Deng, L; Mikael, LG; Pickell, L; Rozen, R; Wu, Q; Yan, J	1
Eijkemans, MJ; Laven, JS; Lindemans, J; Smedts, HP; Steegers, EA; Steegers-Theunissen, RP; Valkenburg, O; van Uitert, EM	1
de Jonge, R; de Vries, JH; Looman, CW; Obermann-Borst, SA; Steegers, EA; Steegers-Theunissen, RP; Vujkovic, M; Wildhagen, MF	1
Alva-Espinoza, C; Arámbula-Meraz, E; Galaviz-Hernández, C; García-Cavazos, R; Ramírez-Dueñas, Mde L; Rangel-Villalobos, H; Sánchez-Urbina, R; Sierra-Ramírez, JA; Torres-Saldúa, R	1
Cevik, A; Gulbahar, O; Kula, S; Oguz, D; Olgunturk, R; Pasaoglu, H; Sanli, C; Tunaoglu, FS	1
Chowdhury, S; Cleves, MA; Erickson, SW; Hobbs, CA; Hu, P; James, SJ; MacLeod, SL; Melnyk, S	1
Rosenquist, TH	1
Chen, X; Hu, B; Li, Y; Zhao, X	1
Cheng, J; Dao, J; Zhao, R; Zhu, W	1
Deng, B; Li, J; Li, W; Tian, Y	1
Boot, MJ; Gittenberger-de Groot, AC; Poelmann, RE; Steegers-Theunissen, RP; van Iperen, L	1
Cleves, MA; Hobbs, CA; James, SJ; Melnyk, S; Zhao, W	2
Cheng, J; Dao, JJ; Li, MY; Li, SQ; Li, Y; Yan, LY; Zhu, WL	1
Cheng, J; Dao, JJ; Li, SQ; Li, Y; Zhu, WL	1
Cohn, JS; Li, D; Liu, Y; Pickell, L; Rozen, R; Wu, Q	1
Cleves, MA; Hobbs, CA; James, SJ; Jernigan, S; Lu, Y; Malik, S; Melnyk, S	1
Bi, Z; Dong, J; Li, Y; Lu, D; Song, F; Wang, G; Wu, J; Zhao, L	1
Cleves, MA; Hobbs, CA; James, SJ; Malik, S; Melnyk, S; Zhao, W	1
Brosstad, F; Holmstrøm, H; Ruud, E; Wesenberg, F	1
Cheng, J; Dao, JJ; Li, SQ; Zhu, WL	1
de Jonge, R; de Vries, JH; Hop, WC; Steegers-Theunissen, RP; Ursem, NT; Verkleij-Hagoort, AC	1
Arrieta, SR; D'Almeida, V; Galdieri, LC; Pedra, CA; Silva, CM	1
Champion, HC; Claeys, MJ; Kass, DA; Moens, AL; Timmermans, JP; Vrints, CJ	1
Ratashak, SA; Rosenquist, TH; Selhub, J	1
Blom, HJ; Cuypers, MH; Eskes, TK; Haagmans, ML; Kapusta, L; Steegers, EA	1
DuBard, M; Johanning, GL; Johnston, KE; Wenstrom, KD	1
Burwash, IG; Chan, KL; Ghani, M; Woodend, K	1
Chen, G; Li, S; Li, Y	1
Chen, X; Li, S; Li, Y; Li, Z; Qi, P	1
Burgoon, JM; Nadeau, M; Sadler, TW; Selhub, J	1

Reviews

3 review(s) available for homocysteine and Abnormality, Heart

Article	Year
Recent advances in understanding the genetics of congenital heart defects. Current opinion in pediatrics, 2013, Volume: 25, Issue:5 Topics: Child; Child, Preschool; DNA Copy Number Variations; Folic Acid; Gene-Environment Interaction; Genes, Modifier; Genome-Wide Association Study; Heart Defects, Congenital; Homocysteine; Humans; Infant; Molecular Sequence Data; Mutation	2013
Folate, homocysteine and the cardiac neural crest. Developmental dynamics : an official publication of the American Association of Anatomists, 2013, Volume: 242, Issue:3 Topics: Animals; DNA Methylation; Folate Receptor 1; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Mitosis; Neural Crest	2013
Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:5 Topics: Animals; Atherosclerosis; Cardiovascular Agents; Cardiovascular Diseases; Endothelium, Vascular; Folic Acid; Heart Defects, Congenital; Hemodynamics; Homocysteine; Humans; Nitric Oxide; Nitric Oxide Synthase Type III	2008

Other Studies

49 other study(ies) available for homocysteine and Abnormality, Heart

Article	Year
Folate Deficiency: A Possible Association with Congenital Heart Defects. Indian journal of pediatrics, 2022, Volume: 89, Issue:10 Topics: Cross-Sectional Studies; Folic Acid; Folic Acid Deficiency; Heart Defects, Congenital; Homocysteine; Humans; Infant; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency	2022
Inhibiting MARSs reduces hyperhomocysteinemia-associated neural tube and congenital heart defects. EMBO molecular medicine, 2020, 03-06, Volume: 12, Issue:3 Topics: Animals; Female; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Male; Methionine-tRNA Ligase; Mice; Mice, Inbred C57BL; Neural Tube Defects; Rats; Rats, Sprague-Dawley; United States	2020
Study on Maternal SNPs of MTHFR Gene and HCY Level Related to Congenital Heart Diseases. Pediatric cardiology, 2021, Volume: 42, Issue:1 Topics: Adult; Case-Control Studies; Child; Female; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Mutation; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Surveys and Questionnaires; Young Adult	2021
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases. Experimental cell research, 2017, 06-01, Volume: 355, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Cells, Cultured; Female; Heart Defects, Congenital; Homocysteine; Humans; Microfilament Proteins; Pregnancy; Proteasome Endopeptidase Complex; Rats	2017
Abnormal Biomarkers of Homocysteine Metabolism in Neonates with Conotruncal Heart Defects. BioMed research international, 2017, Volume: 2017 Topics: Biomarkers; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Male; Metabolic Networks and Pathways	2017
Folate, vitamin B12, homocysteine and polymorphisms in folate metabolizing genes in children with congenital heart disease and their mothers. European journal of clinical nutrition, 2017, Volume: 71, Issue:12 Topics: Adult; Case-Control Studies; Child; Child, Preschool; Ferredoxin-NADP Reductase; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Heart Defects, Congenital; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Polymorphism, Single Nucleotide; Risk Factors; Socioeconomic Factors; Vitamin B 12; Young Adult	2017
Maternal and cord blood homocysteine, vitamin B12, folate, and B-type natriuretic peptide levels at term for predicting congenital heart disease of the neonate: A case-control study. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2020, Volume: 33, Issue:15 Topics: Case-Control Studies; Female; Fetal Blood; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Natriuretic Peptide, Brain; Pregnancy; Vitamin B 12	2020
The heart-placenta axis in the first month of pregnancy: induction and prevention of cardiovascular birth defects. Journal of pregnancy, 2013, Volume: 2013 Topics: Animals; Birds; Cell Differentiation; Dietary Supplements; Disease Models, Animal; Ethanol; Female; Folic Acid; Folic Acid Deficiency; Gestational Age; Heart; Heart Defects, Congenital; Homocysteine; Humans; Lithium Compounds; Maternal Exposure; Mice; Myocytes, Cardiac; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Signal Transduction; Wnt Proteins	2013
Genetic variants reducing MTR gene expression increase the risk of congenital heart disease in Han Chinese populations. European heart journal, 2014, Volume: 35, Issue:11 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Asian People; Case-Control Studies; DNA Methylation; Ferredoxin-NADP Reductase; Gene Expression; Genetic Predisposition to Disease; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; MicroRNAs; Risk Factors; Transcription, Genetic	2014
MTHFR C677T and A1298C gene polymorphisms and their relation to homocysteine level in Egyptian children with congenital heart diseases. Gene, 2013, Oct-15, Volume: 529, Issue:1 Topics: Alleles; Case-Control Studies; Child; Child, Preschool; Egypt; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Factors	2013
Methylene tetrahydrofolate reductase polymorphisms and homocysteine level in heart defects. Pediatrics international : official journal of the Japan Pediatric Society, 2014, Volume: 56, Issue:2 Topics: Child; Female; Heart Defects, Congenital; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic	2014
Departure from the Hardy-Weinberg equilibrium. Gene, 2014, Mar-10, Volume: 537, Issue:2 Topics: Female; Heart Defects, Congenital; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic	2014
Conotruncal heart defects and common variants in maternal and fetal genes in folate, homocysteine, and transsulfuration pathways. Birth defects research. Part A, Clinical and molecular teratology, 2014, Volume: 100, Issue:2 Topics: Adult; Bayes Theorem; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Glutamate-Cysteine Ligase; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Polymorphism, Single Nucleotide; Pregnancy; Prospective Studies; Risk Factors; Thymidylate Synthase	2014
Potential biomarkers predicting risk of pulmonary hypertension in congenital heart disease: the role of homocysteine and hydrogen sulfide. Chinese medical journal, 2014, Volume: 127, Issue:5 Topics: Biomarkers; Child; Child, Preschool; Female; Heart Defects, Congenital; Homocysteine; Humans; Hydrogen Sulfide; Hypertension, Pulmonary; Infant; Infant, Newborn; Male; Prospective Studies	2014
[Correlation between endogenous sulfur dioxide and homocysteine in children with pulmonary arterial hypertension associated with congenital heart disease]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2014, Volume: 52, Issue:8 Topics: Biomarkers; Case-Control Studies; Child, Preschool; Ductus Arteriosus, Patent; Familial Primary Pulmonary Hypertension; Female; Heart Defects, Congenital; Heart Septal Defects; Hemodynamics; Homocysteine; Humans; Infant; Male; Sulfur Dioxide	2014
[Correlation between offspring congenital heart disease and MTHFR 677C/T polymorphism and general status of pregnant women]. Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2015, Volume: 36, Issue:10 Topics: Case-Control Studies; Female; Folic Acid; Gene Frequency; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Prevalence	2015
[CBS gene variations and serum homocysteine level associated with congenital heart defects]. Wei sheng yan jiu = Journal of hygiene research, 2008, Volume: 37, Issue:4 Topics: Adult; Alleles; Case-Control Studies; Child; China; Cystathionine beta-Synthase; Female; Genetic Variation; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Inheritance Patterns; Male; Nuclear Family; Risk Factors	2008
Zinc antagonizes homocysteine-induced fetal heart defects in rats. Cardiovascular toxicology, 2009, Volume: 9, Issue:3 Topics: Animals; Female; Fetal Heart; Heart Defects, Congenital; Homocysteine; Pregnancy; Rats; Rats, Sprague-Dawley; Zinc	2009
Association of congenital cardiovascular malformations with 33 single nucleotide polymorphisms of selected cardiovascular disease-related genes. Birth defects research. Part A, Clinical and molecular teratology, 2010, Volume: 88, Issue:2 Topics: Aortic Coarctation; Aortic Valve Stenosis; Blood Coagulation; Blood Pressure; Cell Communication; Dietary Supplements; Female; Heart Defects, Congenital; Heart Septal Defects, Atrial; Homocysteine; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Prospective Studies; Pulmonary Valve Stenosis; Racial Groups	2010
Double aneuploidy (48,XXY,+21) of maternal origin in a child born to a 13-year-old mother: evaluation of the maternal folate metabolism. Genetic counseling (Geneva, Switzerland), 2009, Volume: 20, Issue:3 Topics: Adolescent; Alleles; Aneuploidy; Brazil; Chromosomes, Human, X; Chromosomes, Human, Y; DNA Mutational Analysis; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Carrier Screening; Genotype; Heart Defects, Congenital; Homocysteine; Homozygote; Humans; Infant; Klinefelter Syndrome; Male; Meiosis; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Nondisjunction, Genetic; Polymorphism, Genetic; Pregnancy; Pregnancy in Adolescence; Sex Chromosome Aberrations; Trisomy	2009
Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice. The American journal of clinical nutrition, 2010, Volume: 91, Issue:4 Topics: Animals; Choline; Diet; Female; Fetal Heart; Heart; Heart Defects, Congenital; Homocysteine; Lipotropic Agents; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Pregnancy; Pregnancy Outcome; Prenatal Nutritional Physiological Phenomena; Riboflavin; Vitamin B Complex	2010
A derangement of the maternal lipid profile is associated with an elevated risk of congenital heart disease in the offspring. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2012, Volume: 22, Issue:6 Topics: Adult; Apolipoproteins B; Body Mass Index; Case-Control Studies; Child; Cholesterol, LDL; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Hyperglycemia; Hyperhomocysteinemia; Logistic Models; Multivariate Analysis; Odds Ratio; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Young Adult	2012
A maternal dietary pattern characterised by fish and seafood in association with the risk of congenital heart defects in the offspring. BJOG : an international journal of obstetrics and gynaecology, 2011, Volume: 118, Issue:10 Topics: Adult; Biomarkers; Case-Control Studies; Feeding Behavior; Female; Fish Products; Heart Defects, Congenital; Homocysteine; Humans; Methylation; Netherlands; Odds Ratio; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Seafood; Surveys and Questionnaires; Vitamin B Complex	2011
Methylenetetrahydrofolate reductase gene 677CT polymorphism and isolated congenital heart disease in a Mexican population. Revista espanola de cardiologia (English ed.), 2012, Volume: 65, Issue:2 Topics: Adolescent; Adult; Alleles; Child; Child, Preschool; DNA; Female; Folic Acid; Gene Frequency; Heart Defects, Congenital; Homocysteine; Humans; Infant; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Polymerase Chain Reaction; Polymorphism, Genetic; Pregnancy; Prenatal Care; Young Adult	2012
Elevated homocysteine and asymmetric dimethyl arginine levels in pulmonary hypertension associated with congenital heart disease. Pediatric cardiology, 2012, Volume: 33, Issue:8 Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiac Catheterization; Case-Control Studies; Child; Child, Preschool; Echocardiography; Enzyme-Linked Immunosorbent Assay; Familial Primary Pulmonary Hypertension; Heart Defects, Congenital; Hemodynamics; Homocysteine; Humans; Hypertension, Pulmonary; Infant; Nitric Oxide; Predictive Value of Tests; ROC Curve; Sensitivity and Specificity; Statistics, Nonparametric	2012
Associations between maternal genotypes and metabolites implicated in congenital heart defects. Molecular genetics and metabolism, 2012, Volume: 107, Issue:3 Topics: Adult; Asymptomatic Diseases; Carbon-Nitrogen Ligases; Case-Control Studies; Catalase; DNA (Cytosine-5-)-Methyltransferases; DNA Modification Methylases; DNA Repair Enzymes; Female; Folic Acid; Genotype; Glutathione; Glutathione Peroxidase; Heart Defects, Congenital; Homocysteine; Humans; Life Style; Male; Methionine; Methionine Adenosyltransferase; Polymorphism, Single Nucleotide; Risk; Tumor Suppressor Proteins	2012
[Relationship between homocysteine-induced apoptosis and teratogenesis in developing avian embryo]. Wei sheng yan jiu = Journal of hygiene research, 1999, Sep-30, Volume: 28, Issue:5 Topics: Animals; Apoptosis; Chick Embryo; Heart Defects, Congenital; Homocysteine; Neural Tube Defects	1999
[Relations of methionine synthase gene variation with congenital heart disease]. Wei sheng yan jiu = Journal of hygiene research, 2004, Volume: 33, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Child; Child, Preschool; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutathione; Heart Defects, Congenital; Heart Septal Defects; Homocysteine; Humans; Infant; Male; Polymorphism, Genetic; Vitamin B 12	2004
[Effects of taurine on the heart defects in chick embryos which induced by homocysteine]. Wei sheng yan jiu = Journal of hygiene research, 2004, Volume: 33, Issue:2 Topics: Animals; Chick Embryo; Heart Defects, Congenital; Homocysteine; Taurine	2004
Cardiac outflow tract malformations in chick embryos exposed to homocysteine. Cardiovascular research, 2004, Nov-01, Volume: 64, Issue:2 Topics: Animals; Apoptosis; Cell Movement; Chick Embryo; DNA-Binding Proteins; Gene Expression Regulation, Developmental; Heart; Heart Defects, Congenital; Homocysteine; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Neural Crest; Transcription Factors	2004
Congenital heart defects and abnormal maternal biomarkers of methionine and homocysteine metabolism. The American journal of clinical nutrition, 2005, Volume: 81, Issue:1 Topics: Adult; Arkansas; Biomarkers; Case-Control Studies; Female; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Life Style; Methionine; Pregnancy; Registries; Risk Factors; S-Adenosylhomocysteine	2005
[Study of serum Hcy and polymorphisms of Hcy metabolic enzymes in 192 families affected by congenital heart disease]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2005, Feb-18, Volume: 37, Issue:1 Topics: Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Vitamin B 12	2005
Relationship between polymorphism of methylenetetrahydrofolate dehydrogenase and congenital heart defect. Biomedical and environmental sciences : BES, 2005, Volume: 18, Issue:1 Topics: Adolescent; Adult; Case-Control Studies; Child; Child, Preschool; China; Female; Folic Acid; Gene Frequency; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mutation; Polymorphism, Genetic	2005
Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice. The American journal of clinical nutrition, 2005, Volume: 82, Issue:1 Topics: Animals; Diet; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Heart Defects, Congenital; Homocysteine; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Pregnancy	2005
Congenital heart defects and maternal biomarkers of oxidative stress. The American journal of clinical nutrition, 2005, Volume: 82, Issue:3 Topics: Adult; Arkansas; Biomarkers; Case-Control Studies; Dipeptides; Female; Folic Acid; Glutathione; Glutathione Disulfide; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Life Style; Oxidative Stress; Pregnancy; Pregnancy Complications; Registries; Risk Factors; S-Adenosylhomocysteine; Vitamin B 6	2005
Congenital heart defects, maternal homocysteine, smoking, and the 677 C>T polymorphism in the methylenetetrahydrofolate reductase gene: evaluating gene-environment interactions. American journal of obstetrics and gynecology, 2006, Volume: 194, Issue:1 Topics: Adult; Case-Control Studies; Cytosine; Female; Genetic Predisposition to Disease; Genotype; Heart Defects, Congenital; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Smoking; Thymine	2006
Homocysteine, hRIP3 and congenital cardiovascular malformations. Anatomy and embryology, 2006, Volume: 211, Issue:3 Topics: Amino Acid Sequence; Animals; Cells, Cultured; Heart; Heart Defects, Congenital; Homocysteine; Humans; Mice; Molecular Sequence Data; Myocytes, Cardiac; Protein Kinases; Receptor-Interacting Protein Serine-Threonine Kinases	2006
Maternal homocysteine and congenital heart defects. Journal of the American College of Cardiology, 2006, Feb-07, Volume: 47, Issue:3 Topics: Adult; Biomarkers; Female; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Pregnancy; Prenatal Diagnosis	2006
Children with acute lymphoblastic leukaemia have high plasma levels of total homocysteine at time of diagnosis. Scandinavian journal of clinical and laboratory investigation, 2006, Volume: 66, Issue:1 Topics: Adolescent; Antithrombins; Child; Child, Preschool; Heart Defects, Congenital; Homocysteine; Humans; Infant; Lipoprotein(a); Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein C; Protein S; Remission Induction; Risk Factors; Thrombosis	2006
[Relations between serum homocysteine and folic acid levels with congenital heart disease]. Wei sheng yan jiu = Journal of hygiene research, 2005, Volume: 34, Issue:6 Topics: Adolescent; Adult; Case-Control Studies; Child; Child, Preschool; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Infant; Male; Parents; Vitamin B 12; Young Adult	2005
Dietary intake of B-vitamins in mothers born a child with a congenital heart defect. European journal of nutrition, 2006, Volume: 45, Issue:8 Topics: Adult; Case-Control Studies; Dietary Proteins; Educational Status; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Logistic Models; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Nutritional Status; Pregnancy; Pregnancy Complications; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex	2006
Homocysteine concentrations and molecular analysis in patients with congenital heart defects. Archives of medical research, 2007, Volume: 38, Issue:2 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Alleles; Carbon-Nitrogen Ligases; Child, Preschool; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Heart Defects, Congenital; Homocysteine; Humans; Male; Mutation; Vitamin B 12	2007
Homocysteine induces congenital defects of the heart and neural tube: effect of folic acid. Proceedings of the National Academy of Sciences of the United States of America, 1996, Dec-24, Volume: 93, Issue:26 Topics: Animals; Chick Embryo; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Folic Acid; Gastrula; Heart Defects, Congenital; Homocysteine; Mice; Neural Tube Defects; Teratogens	1996
Congenital heart defects and maternal derangement of homocysteine metabolism. The Journal of pediatrics, 1999, Volume: 135, Issue:6 Topics: Adult; Case-Control Studies; Female; Heart Defects, Congenital; Homocysteine; Humans; Infant; Mothers; Postpartum Period; Risk Factors	1999
Association of the C677T methylenetetrahydrofolate reductase mutation and elevated homocysteine levels with congenital cardiac malformations. American journal of obstetrics and gynecology, 2001, Volume: 184, Issue:5 Topics: Amniotic Fluid; Chromatography, High Pressure Liquid; Electrophoresis, Agar Gel; Female; Fetal Heart; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Pregnancy	2001
Case-controlled study to assess risk factors for aortic stenosis in congenitally bicuspid aortic valve. The American journal of cardiology, 2001, Sep-15, Volume: 88, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Case-Control Studies; Cholesterol, HDL; Echocardiography; Female; Heart Defects, Congenital; Homocysteine; Humans; Incidence; Male; Medical Records; Middle Aged; Ontario; Prospective Studies; Risk Factors; Surveys and Questionnaires	2001
[The relationship between HCY-2 gene and congenital heart teratogenesis in early chick embryos]. Zhonghua yi xue za zhi, 2000, Volume: 80, Issue:2 Topics: Animals; Cardiovascular System; Chick Embryo; Heart Defects, Congenital; Homocysteine; Immunohistochemistry; Teratogens	2000
[Effects of homocysteine on cardiovascular development in early chicken embryo]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1999, Volume: 33, Issue:3 Topics: Animals; Cardiovascular System; Chick Embryo; Folic Acid; Heart Defects, Congenital; Homocysteine; Vitamin B 12	1999
Investigation of the effects of folate deficiency on embryonic development through the establishment of a folate deficient mouse model. Teratology, 2002, Volume: 65, Issue:5 Topics: Animals; Body Weight; Cleft Palate; Disease Models, Animal; Female; Folic Acid; Folic Acid Deficiency; Heart Defects, Congenital; Homocysteine; Male; Mice; Mice, Inbred ICR; Neural Tube Defects; Pregnancy	2002